Gene Symbol | PLK4 |
Entrez Gene ID | 10733 |
Full Name | polo like kinase 4 |
Synonyms | MCCRP2,SAK,STK18 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a member of the polo family of serine/threonine protein kinases. The protein localizes to centrioles, complex microtubule-based structures found in centrosomes, and regulates centriole duplication during the cell cycle. Three alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jun 2010]. |
Disorder MIM: | |
Disorder Html: | Microcephaly and chorioretinopathy, autosomal recessive, 2, 616171 (3) |