ADCY1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ADCY1
Entrez Gene ID	107
Full Name	adenylate cyclase 1
Synonyms	AC1,DFNB44
General protein information	Preferred Names adenylate cyclase 1 Names adenylate cyclase type 1 3',5'-cyclic AMP synthetase ATP pyrophosphate-lyase 1 Ca(2+)/calmodulin-activated adenylyl cyclase adenyl cyclase adenylate cyclase 1 (brain) adenylate cyclase type I adenylyl cyclase 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7p12.3
Summary	This gene encodes a member of the of adenylate cyclase gene family that is primarily expressed in the brain. This protein is regulated by calcium/calmodulin concentration and may be involved in brain development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013].
Disorder MIM:	103072
Disorder Html:	?Deafness, autosomal recessive 44, 610154 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_021116.2	NP_066939.1	adenylate cyclase type 1 isoform 1
XM_005249585.2	XP_005249642.1	adenylate cyclase type 1 isoform X2
XM_005249584.3	XP_005249641.1	adenylate cyclase type 1 isoform X1
NM_021116.3	NP_066939.1	adenylate cyclase type 1 isoform 1
NM_021116.4	NP_066939.1	adenylate cyclase type 1 isoform 1
NM_001281768.1	NP_001268697.1	adenylate cyclase type 1 isoform 2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	ADCY1	XP_519081.3
	ADCY1	XP_001086268.1
Mus musculus (house mouse)	Adcy1	NP_033752.1
Gallus gallus (chicken)	ADCY1	XP_418883.4
Xenopus tropicalis (tropical clawed frog)	adcy1	XP_002933461.1
Danio rerio (zebrafish)	adcy1a	NP_001161821.1
Homo sapiens (human)	ADCY1	NP_066939.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000727	XP_559367.4
Canis lupus familiaris (dog)	ADCY1	XP_849081.3
Bos taurus (cattle)	ADCY1	NP_776654.1
Rattus norvegicus (Norway rat)	Adcy1	NP_001100709.1
Drosophila melanogaster (fruit fly)	rut	NP_511156.2

Gene Ontology
Bibliography

Related articles in PubMed

Protein kinase A inhibition facilitates the antitumor activity of xanthohumol, a valosin-containing protein inhibitor.
Shikata Y, Yoshimaru T, Komatsu M, Katoh H, Sato R, Kanagaki S, Okazaki Y, Toyokuni S, Tashiro E, Ishikawa S, Katagiri T, Imoto M
Cancer science108(4)785-794(2017 Apr)

Identification of a selective small-molecule inhibitor of type 1 adenylyl cyclase activity with analgesic properties.
Brust TF, Alongkronrusmee D, Soto-Velasquez M, Baldwin TA, Ye Z, Dai M, Dessauer CW, van Rijn RM, Watts VJ
Science signaling10(467)(2017 Feb)

STC1 interference on calcitonin family of receptors signaling during osteoblastogenesis via adenylate cyclase inhibition.
Terra SR, Cardoso JC, F?lix RC, Martins LA, Souza DO, Guma FC, Can?rio AV, Schein V
Molecular and cellular endocrinology40378-87(2015 Mar)

Membranous adenylyl cyclase 1 activation is regulated by oxidation of N- and C-terminal methionine residues in calmodulin.
L?bker C, Urbauer RJ, Moskovitz J, Dove S, Weisemann J, Fedorova M, Urbauer JL, Seifert R
Biochemical pharmacology93(2)196-209(2015 Jan)

Overexpression of the type 1 adenylyl cyclase in the forebrain leads to deficits of behavioral inhibition.
Chen X, Cao H, Saraf A, Zweifel LS, Storm DR
The Journal of neuroscience : the official journal of the Society for Neuroscience35(1)339-51(2015 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data show that the adenylate cyclase (AC) pathway as genes relating to the antitumor activity of xanthohumol (XN) against tumor cells, and the pathway regulates various cellular functions via activating protein kinase A (PKA)-dependent phosphorylation.
Title: Protein kinase A inhibition facilitates the antitumor activity of xanthohumol, a valosin-containing protein inhibitor.

data indicate that ST034307 is a selective small-molecule inhibitor of AC1 and suggest that selective AC1 inhibitors may be useful for managing pain.
Title: Identification of a selective small-molecule inhibitor of type 1 adenylyl cyclase activity with analgesic properties.

STC1 interferes with CALCRL signaling during osteoblastogenesis via adenylate cyclase inhibition.
Title: STC1 interference on calcitonin family of receptors signaling during osteoblastogenesis via adenylate cyclase inhibition.

AC1 catalytic activity can be adjusted by mediating calmodulin activation of AC1 by reversible methionine oxidation in calmodulin.
Title: Membranous adenylyl cyclase 1 activation is regulated by oxidation of N- and C-terminal methionine residues in calmodulin.

Increased expression of AC1 in the forebrain leads to deficits in behavioral inhibition.
Title: Overexpression of the type 1 adenylyl cyclase in the forebrain leads to deficits of behavioral inhibition.

The following ADCY1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ADCY1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu30550	NM_021116.4 Latest version!	Homo sapiens adenylate cyclase 1 (ADCY1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$399.50-$559.30 $799.00
OHu00606	NM_001281768.1 Latest version!	Homo sapiens adenylate cyclase 1 (ADCY1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu41062	XM_005249584.3 Latest version!	Homo sapiens adenylate cyclase 1 (ADCY1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$475.30 $679.00
OHu41063	XM_005249585.2 Latest version!	Homo sapiens adenylate cyclase 1 (ADCY1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
View Old Accession Versions >>
OHu30550	NM_021116.2	Homo sapiens adenylate cyclase 1 (ADCY1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$399.50-$559.30 $799.00
OHu30550	NM_021116.3	Homo sapiens adenylate cyclase 1 (ADCY1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$399.50-$559.30 $799.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ADCY1 ( NM_021116.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_066939.1 Homo sapiens adenylate cyclase 1 (ADCY1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu30550
Clone ID Related Accession (Same CDS sequence)	NM_021116.2 , NM_021116.3 , NM_021116.4
Accession Version	NM_021116.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3360bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-05-01
Organism	Homo sapiens(Human)
Product	adenylate cyclase type 1 isoform 1
Comment	REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF497515.1, AB209496.1 and AC091439.5. This sequence is a reference standard in the RefSeqGene project. On Feb 22, 2008 this sequence version replaced NM_021116.1. Transcript Variant: This variant (1) represents the loner transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB209496.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144120 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGGGG CGCCGCGCGG CGGAGGCGGC GGCGGAGGCG GCGCGGGCGA GCCCGGGGGC 
GCCGAGCGGG CGGCCGGGAC AAGCCGCCGG CGCGGGCTCC GGGCGTGCGA CGAGGAGTTC 
GCTTGCCCAG AGCTGGAGGC GCTGTTCCGC GGCTACACGC TGCGGCTGGA GCAGGCGGCC 
ACGCTGAAGG CGCTGGCCGT TCTCAGCCTG CTGGCGGGCG CGCTGGCGCT GGCCGAGCTG 
CTGGGCGCGC CGGGGCCCGC GCCCGGCCTG GCCAAGGGCT CACACCCGGT GCACTGCGTC 
CTCTTCCTGG CGCTGCTCGT GGTAACCAAC GTCCGGTCCC TGCAGGTGCC CCAGCTGCAG 
CAGGTCGGCC AGCTGGCGCT GCTCTTCAGC CTCACCTTCG CGCTGCTCTG CTGTCCTTTC 
GCGCTGGGCG GCCCCGCCCG GGGTTCCGCC GGGGCCGCTG GGGGGCCAGC GACCGCCGAA 
CAAGGGGTTT GGCAGCTCCT TTTGGTCACC TTCGTGTCCT ATGCCTTGCT GCCCGTGCGC 
AGCCTGCTGG CCATAGGCTT TGGGCTCGTG GTGGCTGCGT CGCACTTGCT GGTCACAGCC 
ACCTTGGTCC CCGCCAAGCG CCCACGTCTC TGGAGGACGC TCGGTGCCAA TGCCTTGCTC 
TTCGTCGGTG TGAACATGTA TGGGGTCTTT GTGCGGATTC TGACTGAGCG TTCACAGAGG 
AAGGCGTTCC TGCAGGCCCG GAGCTGCATT GAGGACCGAC TGAGGCTGGA GGATGAGAAC 
GAGAAGCAGG AGCGGCTCCT CATGAGCCTC CTGCCCCGGA ACGTTGCCAT GGAGATGAAG 
GAGGACTTCC TGAAGCCCCC TGAGAGGATT TTCCACAAGA TTTACATCCA GAGGCACGAC 
AATGTGAGCA TCCTGTTTGC TGACATCGTG GGTTTCACGG GCTTGGCATC CCAGTGCACA 
GCCCAGGAGC TGGTGAAACT CCTCAATGAG CTCTTCGGCA AGTTCGATGA ATTAGCCACG 
GAGAACCACT GTCGCCGCAT CAAGATTCTC GGGGACTGCT ACTACTGCGT GTCGGGCCTC 
ACCCAGCCCA AGACTGACCA TGCCCACTGC TGTGTGGAGA TGGGACTCGA CATGATTGAT 
ACCATCACAT CTGTGGCTGA AGCCACCGAG GTGGATCTGA ACATGCGTGT GGGTCTGCAC 
ACGGGCAGGG TCCTCTGTGG TGTCCTGGGC TTGCGCAAGT GGCAGTACGA CGTGTGGTCC 
AATGATGTGA CCTTGGCCAA TGTCATGGAA GCCGCTGGCC TGCCAGGGAA GGTTCATATC 
ACAAAGACGA CCCTAGCGTG CTTGAATGGG GACTACGAGG TAGAACCGGG TTACGGACAT 
GAGAGGAACA GTTTCTTGAA AACTCATAAC ATCGAAACCT TTTTTATTGT GCCATCCCAT 
CGCCGAAAGA TATTTCCAGG CCTGATTCTC TCAGATATAA AACCGGCCAA AAGGATGAAG 
TTCAAGACTG TCTGCTACCT GCTGGTGCAG CTCATGCACT GCCGGAAAAT GTTCAAGGCC 
GAGATCCCCT TCTCCAATGT CATGACCTGC GAGGACGATG ACAAGCGGAG GGCATTAAGA 
ACAGCCTCGG AAAAACTCAG AAACCGCTCA TCTTTTTCTA CCAACGTTGT CTACACCACC 
CCGGGCACTC GCGTCAACAG GTACATCAGC CGCCTCTTAG AAGCCCGCCA GACAGAGCTG 
GAGATGGCAG ACCTGAACTT CTTTACCCTG AAGTACAAAC ATGTCGAACG GGAGCAAAAG 
TACCACCAGC TTCAGGACGA GTATTTCACC AGCGCCGTTG TCCTCACCCT CATCCTGGCT 
GCCTTATTTG GCCTTGTCTA CCTTCTAATA TTCCCACAGA GTGTGGTCGT CCTGCTCCTG 
CTAGTATTCT GCATCTGCTT CCTGGTGGCC TGTGTCCTGT ACCTGCACAT CACCCGGGTC 
CAGTGTTTTC CAGGGTGCCT GACGATTCAG ATTCGCACTG TCCTGTGTAT TTTCATAGTG 
GTCTTAATCT ACTCAGTAGC CCAAGGTTGT GTGGTGGGCT GCCTGCCTTG GGCCTGGAGC 
TCCAAGCCCA ACAGTTCCCT GGTGGTCCTT TCGTCTGGGG GCCAGCGCAC AGCCCTGCCC 
ACCCTGCCCT GCGAGTCTAC ACACCATGCC CTGCTCTGCT GCCTGGTGGG CACCCTCCCG 
CTAGCCATAT TTTTCCGGGT GTCCTCCTTG CCAAAAATGA TCCTGCTCTC CGGGCTCACC 
ACGTCCTACA TCCTCGTTCT GGAGCTCAGC GGATACACCA GGACTGGGGG TGGTGCCGTC 
TCCGGGCGCA GCTACGAGCC GATTGTGGCC ATCCTGCTCT TCTCCTGTGC GCTGGCCCTG 
CATGCCAGGC AGGTGGACAT CAGGCTGAGG CTGGACTACC TCTGGGCCGC ACAGGCAGAG 
GAGGAGCGAG AGGACATGGA GAAGGTGAAG CTGGACAACA GGCGCATCCT CTTCAACCTC 
CTGCCGGCCC ACGTCGCCCA GCACTTCCTC ATGTCCAACC CTCGGAACAT GGACCTCTAC 
TACCAGTCCT ACTCCCAGGT GGGCGTCATG TTTGCCTCCA TCCCCAACTT CAATGACTTC 
TACATCGAGC TGGACGGCAA CAACATGGGG GTGGAGTGTC TGCGGCTTCT CAACGAGATC 
ATCGCCGACT TTGACGAGCT CATGGAAAAA GACTTTTACA AGGACATAGA GAAGATCAAG 
ACCATCGGGA GCACCTACAT GGCCGCTGTG GGGCTAGCGC CCACCTCGGG GACCAAGGCT 
AAGAAGTCCA TCTCCTCCCA CCTGAGCACG CTGGCGGACT TTGCCATTGA GATGTTTGAC 
GTTCTGGATG AAATCAACTA CCAGTCTTAC AACGACTTTG TCCTCCGAGT TGGCATCAAT 
GTTGGCCCTG TGGTGGCTGG AGTGATTGGC GCTCGCAGGC CCCAGTACGA CATCTGGGGA 
AACACAGTCA ACGTGGCCAG TCGGATGGAT AGCACAGGGG TCCAGGGCAG AATCCAGGTG 
ACTGAGGAAG TCCACCGGCT GCTGAGAAGG TGCCCCTACC ACTTTGTGTG CCGAGGCAAA 
GTCAGTGTCA AGGGCAAAGG CGAGATGTTG ACATACTTTC TAGAAGGCAG GACTGATGGA 
AACGGCTCCC AAATCAGGTC CCTGGGCTTG GATCGGAAAA TGTGTCCATT TGGGAGAGCT 
GGCCTTCAGG GCAGACGTCC CCCCGTGTGC CCCATGCCTG GCGTCTCAGT CAGGGCTGGG 
CTCCCTCCAC ACTCCCCAGG CCAGTACCTG CCCTCTGCAG CAGCTGGGAA GGAGGCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_066939.1
CDS	19..3378
Translation	MAGAPRGGGGGGGGAGEPGGAERAAGTSRRRGLRACDEEFACPELEALFRGYTLRLEQAATLKALAVLSLLAGALALAELLGAPGPAPGLAKGSHPVHCVLFLALLVVTNVRSLQVPQLQQVGQLALLFSLTFALLCCPFALGGPARGSAGAAGGPATAEQGVWQLLLVTFVSYALLPVRSLLAIGFGLVVAASHLLVTATLVPAKRPRLWRTLGANALLFVGVNMYGVFVRILTERSQRKAFLQARSCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGYGHERNSFLKTHNIETFFIVPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKRRALRTASEKLRNRSSFSTNVVYTTPGTRVNRYISRLLEARQTELEMADLNFFTLKYKHVEREQKYHQLQDEYFTSAVVLTLILAALFGLVYLLIFPQSVVVLLLLVFCICFLVACVLYLHITRVQCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWAWSSKPNSSLVVLSSGGQRTALPTLPCESTHHALLCCLVGTLPLAIFFRVSSLPKMILLSGLTTSYILVLELSGYTRTGGGAVSGRSYEPIVAILLFSCALALHARQVDIRLRLDYLWAAQAEEEREDMEKVKLDNRRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEIIADFDELMEKDFYKDIEKIKTIGSTYMAAVGLAPTSGTKAKKSISSHLSTLADFAIEMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGRIQVTEEVHRLLRRCPYHFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQIRSLGLDRKMCPFGRAGLQGRRPPVCPMPGVSVRAGLPPHSPGQYLPSAAAGKEA

Target ORF information:

RefSeq Version	NM_021116.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens adenylate cyclase 1 (ADCY1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021116.2

ORF Insert Sequence:

ATGGCGGGGG CGCCGCGCGG CGGAGGCGGC GGCGGAGGCG GCGCGGGCGA GCCCGGGGGC 
GCCGAGCGGG CGGCCGGGAC AAGCCGCCGG CGCGGGCTCC GGGCGTGCGA CGAGGAGTTC 
GCTTGCCCAG AGCTGGAGGC GCTGTTCCGC GGCTACACGC TGCGGCTGGA GCAGGCGGCC 
ACGCTGAAGG CGCTGGCCGT TCTCAGCCTG CTGGCGGGCG CGCTGGCGCT GGCCGAGCTG 
CTGGGCGCGC CGGGGCCCGC GCCCGGCCTG GCCAAGGGCT CACACCCGGT GCACTGCGTC 
CTCTTCCTGG CGCTGCTCGT GGTAACCAAC GTCCGGTCCC TGCAGGTGCC CCAGCTGCAG 
CAGGTCGGCC AGCTGGCGCT GCTCTTCAGC CTCACCTTCG CGCTGCTCTG CTGTCCTTTC 
GCGCTGGGCG GCCCCGCCCG GGGTTCCGCC GGGGCCGCTG GGGGGCCAGC GACCGCCGAA 
CAAGGGGTTT GGCAGCTCCT TTTGGTCACC TTCGTGTCCT ATGCCTTGCT GCCCGTGCGC 
AGCCTGCTGG CCATAGGCTT TGGGCTCGTG GTGGCTGCGT CGCACTTGCT GGTCACAGCC 
ACCTTGGTCC CCGCCAAGCG CCCACGTCTC TGGAGGACGC TCGGTGCCAA TGCCTTGCTC 
TTCGTCGGTG TGAACATGTA TGGGGTCTTT GTGCGGATTC TGACTGAGCG TTCACAGAGG 
AAGGCGTTCC TGCAGGCCCG GAGCTGCATT GAGGACCGAC TGAGGCTGGA GGATGAGAAC 
GAGAAGCAGG AGCGGCTCCT CATGAGCCTC CTGCCCCGGA ACGTTGCCAT GGAGATGAAG 
GAGGACTTCC TGAAGCCCCC TGAGAGGATT TTCCACAAGA TTTACATCCA GAGGCACGAC 
AATGTGAGCA TCCTGTTTGC TGACATCGTG GGTTTCACGG GCTTGGCATC CCAGTGCACA 
GCCCAGGAGC TGGTGAAACT CCTCAATGAG CTCTTCGGCA AGTTCGATGA ATTAGCCACG 
GAGAACCACT GTCGCCGCAT CAAGATTCTC GGGGACTGCT ACTACTGCGT GTCGGGCCTC 
ACCCAGCCCA AGACTGACCA TGCCCACTGC TGTGTGGAGA TGGGACTCGA CATGATTGAT 
ACCATCACAT CTGTGGCTGA AGCCACCGAG GTGGATCTGA ACATGCGTGT GGGTCTGCAC 
ACGGGCAGGG TCCTCTGTGG TGTCCTGGGC TTGCGCAAGT GGCAGTACGA CGTGTGGTCC 
AATGATGTGA CCTTGGCCAA TGTCATGGAA GCCGCTGGCC TGCCAGGGAA GGTTCATATC 
ACAAAGACGA CCCTAGCGTG CTTGAATGGG GACTACGAGG TAGAACCGGG TTACGGACAT 
GAGAGGAACA GTTTCTTGAA AACTCATAAC ATCGAAACCT TTTTTATTGT GCCATCCCAT 
CGCCGAAAGA TATTTCCAGG CCTGATTCTC TCAGATATAA AACCGGCCAA AAGGATGAAG 
TTCAAGACTG TCTGCTACCT GCTGGTGCAG CTCATGCACT GCCGGAAAAT GTTCAAGGCC 
GAGATCCCCT TCTCCAATGT CATGACCTGC GAGGACGATG ACAAGCGGAG GGCATTAAGA 
ACAGCCTCGG AAAAACTCAG AAACCGCTCA TCTTTTTCTA CCAACGTTGT CTACACCACC 
CCGGGCACTC GCGTCAACAG GTACATCAGC CGCCTCTTAG AAGCCCGCCA GACAGAGCTG 
GAGATGGCAG ACCTGAACTT CTTTACCCTG AAGTACAAAC ATGTCGAACG GGAGCAAAAG 
TACCACCAGC TTCAGGACGA GTATTTCACC AGCGCCGTTG TCCTCACCCT CATCCTGGCT 
GCCTTATTTG GCCTTGTCTA CCTTCTAATA TTCCCACAGA GTGTGGTCGT CCTGCTCCTG 
CTAGTATTCT GCATCTGCTT CCTGGTGGCC TGTGTCCTGT ACCTGCACAT CACCCGGGTC 
CAGTGTTTTC CAGGGTGCCT GACGATTCAG ATTCGCACTG TCCTGTGTAT TTTCATAGTG 
GTCTTAATCT ACTCAGTAGC CCAAGGTTGT GTGGTGGGCT GCCTGCCTTG GGCCTGGAGC 
TCCAAGCCCA ACAGTTCCCT GGTGGTCCTT TCGTCTGGGG GCCAGCGCAC AGCCCTGCCC 
ACCCTGCCCT GCGAGTCTAC ACACCATGCC CTGCTCTGCT GCCTGGTGGG CACCCTCCCG 
CTAGCCATAT TTTTCCGGGT GTCCTCCTTG CCAAAAATGA TCCTGCTCTC CGGGCTCACC 
ACGTCCTACA TCCTCGTTCT GGAGCTCAGC GGATACACCA GGACTGGGGG TGGTGCCGTC 
TCCGGGCGCA GCTACGAGCC GATTGTGGCC ATCCTGCTCT TCTCCTGTGC GCTGGCCCTG 
CATGCCAGGC AGGTGGACAT CAGGCTGAGG CTGGACTACC TCTGGGCCGC ACAGGCAGAG 
GAGGAGCGAG AGGACATGGA GAAGGTGAAG CTGGACAACA GGCGCATCCT CTTCAACCTC 
CTGCCGGCCC ACGTCGCCCA GCACTTCCTC ATGTCCAACC CTCGGAACAT GGACCTCTAC 
TACCAGTCCT ACTCCCAGGT GGGCGTCATG TTTGCCTCCA TCCCCAACTT CAATGACTTC 
TACATCGAGC TGGACGGCAA CAACATGGGG GTGGAGTGTC TGCGGCTTCT CAACGAGATC 
ATCGCCGACT TTGACGAGCT CATGGAAAAA GACTTTTACA AGGACATAGA GAAGATCAAG 
ACCATCGGGA GCACCTACAT GGCCGCTGTG GGGCTAGCGC CCACCTCGGG GACCAAGGCT 
AAGAAGTCCA TCTCCTCCCA CCTGAGCACG CTGGCGGACT TTGCCATTGA GATGTTTGAC 
GTTCTGGATG AAATCAACTA CCAGTCTTAC AACGACTTTG TCCTCCGAGT TGGCATCAAT 
GTTGGCCCTG TGGTGGCTGG AGTGATTGGC GCTCGCAGGC CCCAGTACGA CATCTGGGGA 
AACACAGTCA ACGTGGCCAG TCGGATGGAT AGCACAGGGG TCCAGGGCAG AATCCAGGTG 
ACTGAGGAAG TCCACCGGCT GCTGAGAAGG TGCCCCTACC ACTTTGTGTG CCGAGGCAAA 
GTCAGTGTCA AGGGCAAAGG CGAGATGTTG ACATACTTTC TAGAAGGCAG GACTGATGGA 
AACGGCTCCC AAATCAGGTC CCTGGGCTTG GATCGGAAAA TGTGTCCATT TGGGAGAGCT 
GGCCTTCAGG GCAGACGTCC CCCCGTGTGC CCCATGCCTG GCGTCTCAGT CAGGGCTGGG 
CTCCCTCCAC ACTCCCCAGG CCAGTACCTG CCCTCTGCAG CAGCTGGGAA GGAGGCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADCY1 ( NM_021116.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_066939.1 Homo sapiens adenylate cyclase 1 (ADCY1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu30550
Clone ID Related Accession (Same CDS sequence)	NM_021116.2 , NM_021116.3 , NM_021116.4
Accession Version	NM_021116.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3360bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-27
Organism	Homo sapiens(human)
Product	adenylate cyclase type 1 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC069008.6, AF497515.1, AB209496.1 and AC091439.5. This sequence is a reference standard in the RefSeqGene project. On Jun 20, 2017 this sequence version replaced NM_021116.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB209496.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGGGG CGCCGCGCGG CGGAGGCGGC GGCGGAGGCG GCGCGGGCGA GCCCGGGGGC 
GCCGAGCGGG CGGCCGGGAC AAGCCGCCGG CGCGGGCTCC GGGCGTGCGA CGAGGAGTTC 
GCTTGCCCAG AGCTGGAGGC GCTGTTCCGC GGCTACACGC TGCGGCTGGA GCAGGCGGCC 
ACGCTGAAGG CGCTGGCCGT TCTCAGCCTG CTGGCGGGCG CGCTGGCGCT GGCCGAGCTG 
CTGGGCGCGC CGGGGCCCGC GCCCGGCCTG GCCAAGGGCT CACACCCGGT GCACTGCGTC 
CTCTTCCTGG CGCTGCTCGT GGTAACCAAC GTCCGGTCCC TGCAGGTGCC CCAGCTGCAG 
CAGGTCGGCC AGCTGGCGCT GCTCTTCAGC CTCACCTTCG CGCTGCTCTG CTGTCCTTTC 
GCGCTGGGCG GCCCCGCCCG GGGTTCCGCC GGGGCCGCTG GGGGGCCAGC GACCGCCGAA 
CAAGGGGTTT GGCAGCTCCT TTTGGTCACC TTCGTGTCCT ATGCCTTGCT GCCCGTGCGC 
AGCCTGCTGG CCATAGGCTT TGGGCTCGTG GTGGCTGCGT CGCACTTGCT GGTCACAGCC 
ACCTTGGTCC CCGCCAAGCG CCCACGTCTC TGGAGGACGC TCGGTGCCAA TGCCTTGCTC 
TTCGTCGGTG TGAACATGTA TGGGGTCTTT GTGCGGATTC TGACTGAGCG TTCACAGAGG 
AAGGCGTTCC TGCAGGCCCG GAGCTGCATT GAGGACCGAC TGAGGCTGGA GGATGAGAAC 
GAGAAGCAGG AGCGGCTCCT CATGAGCCTC CTGCCCCGGA ACGTTGCCAT GGAGATGAAG 
GAGGACTTCC TGAAGCCCCC TGAGAGGATT TTCCACAAGA TTTACATCCA GAGGCACGAC 
AATGTGAGCA TCCTGTTTGC TGACATCGTG GGTTTCACGG GCTTGGCATC CCAGTGCACA 
GCCCAGGAGC TGGTGAAACT CCTCAATGAG CTCTTCGGCA AGTTCGATGA ATTAGCCACG 
GAGAACCACT GTCGCCGCAT CAAGATTCTC GGGGACTGCT ACTACTGCGT GTCGGGCCTC 
ACCCAGCCCA AGACTGACCA TGCCCACTGC TGTGTGGAGA TGGGACTCGA CATGATTGAT 
ACCATCACAT CTGTGGCTGA AGCCACCGAG GTGGATCTGA ACATGCGTGT GGGTCTGCAC 
ACGGGCAGGG TCCTCTGTGG TGTCCTGGGC TTGCGCAAGT GGCAGTACGA CGTGTGGTCC 
AATGATGTGA CCTTGGCCAA TGTCATGGAA GCCGCTGGCC TGCCAGGGAA GGTTCATATC 
ACAAAGACGA CCCTAGCGTG CTTGAATGGG GACTACGAGG TAGAACCGGG TTACGGACAT 
GAGAGGAACA GTTTCTTGAA AACTCATAAC ATCGAAACCT TTTTTATTGT GCCATCCCAT 
CGCCGAAAGA TATTTCCAGG CCTGATTCTC TCAGATATAA AACCGGCCAA AAGGATGAAG 
TTCAAGACTG TCTGCTACCT GCTGGTGCAG CTCATGCACT GCCGGAAAAT GTTCAAGGCC 
GAGATCCCCT TCTCCAATGT CATGACCTGC GAGGACGATG ACAAGCGGAG GGCATTAAGA 
ACAGCCTCGG AAAAACTCAG AAACCGCTCA TCTTTTTCTA CCAACGTTGT CTACACCACC 
CCGGGCACTC GCGTCAACAG GTACATCAGC CGCCTCTTAG AAGCCCGCCA GACAGAGCTG 
GAGATGGCAG ACCTGAACTT CTTTACCCTG AAGTACAAAC ATGTCGAACG GGAGCAAAAG 
TACCACCAGC TTCAGGACGA GTATTTCACC AGCGCCGTTG TCCTCACCCT CATCCTGGCT 
GCCTTATTTG GCCTTGTCTA CCTTCTAATA TTCCCACAGA GTGTGGTCGT CCTGCTCCTG 
CTAGTATTCT GCATCTGCTT CCTGGTGGCC TGTGTCCTGT ACCTGCACAT CACCCGGGTC 
CAGTGTTTTC CAGGGTGCCT GACGATTCAG ATTCGCACTG TCCTGTGTAT TTTCATAGTG 
GTCTTAATCT ACTCAGTAGC CCAAGGTTGT GTGGTGGGCT GCCTGCCTTG GGCCTGGAGC 
TCCAAGCCCA ACAGTTCCCT GGTGGTCCTT TCGTCTGGGG GCCAGCGCAC AGCCCTGCCC 
ACCCTGCCCT GCGAGTCTAC ACACCATGCC CTGCTCTGCT GCCTGGTGGG CACCCTCCCG 
CTAGCCATAT TTTTCCGGGT GTCCTCCTTG CCAAAAATGA TCCTGCTCTC CGGGCTCACC 
ACGTCCTACA TCCTCGTTCT GGAGCTCAGC GGATACACCA GGACTGGGGG TGGTGCCGTC 
TCCGGGCGCA GCTACGAGCC GATTGTGGCC ATCCTGCTCT TCTCCTGTGC GCTGGCCCTG 
CATGCCAGGC AGGTGGACAT CAGGCTGAGG CTGGACTACC TCTGGGCCGC ACAGGCAGAG 
GAGGAGCGAG AGGACATGGA GAAGGTGAAG CTGGACAACA GGCGCATCCT CTTCAACCTC 
CTGCCGGCCC ACGTCGCCCA GCACTTCCTC ATGTCCAACC CTCGGAACAT GGACCTCTAC 
TACCAGTCCT ACTCCCAGGT GGGCGTCATG TTTGCCTCCA TCCCCAACTT CAATGACTTC 
TACATCGAGC TGGACGGCAA CAACATGGGG GTGGAGTGTC TGCGGCTTCT CAACGAGATC 
ATCGCCGACT TTGACGAGCT CATGGAAAAA GACTTTTACA AGGACATAGA GAAGATCAAG 
ACCATCGGGA GCACCTACAT GGCCGCTGTG GGGCTAGCGC CCACCTCGGG GACCAAGGCT 
AAGAAGTCCA TCTCCTCCCA CCTGAGCACG CTGGCGGACT TTGCCATTGA GATGTTTGAC 
GTTCTGGATG AAATCAACTA CCAGTCTTAC AACGACTTTG TCCTCCGAGT TGGCATCAAT 
GTTGGCCCTG TGGTGGCTGG AGTGATTGGC GCTCGCAGGC CCCAGTACGA CATCTGGGGA 
AACACAGTCA ACGTGGCCAG TCGGATGGAT AGCACAGGGG TCCAGGGCAG AATCCAGGTG 
ACTGAGGAAG TCCACCGGCT GCTGAGAAGG TGCCCCTACC ACTTTGTGTG CCGAGGCAAA 
GTCAGTGTCA AGGGCAAAGG CGAGATGTTG ACATACTTTC TAGAAGGCAG GACTGATGGA 
AACGGCTCCC AAATCAGGTC CCTGGGCTTG GATCGGAAAA TGTGTCCATT TGGGAGAGCT 
GGCCTTCAGG GCAGACGTCC CCCCGTGTGC CCCATGCCTG GCGTCTCAGT CAGGGCTGGG 
CTCCCTCCAC ACTCCCCAGG CCAGTACCTG CCCTCTGCAG CAGCTGGGAA GGAGGCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_066939.1
CDS	23..3382
Translation	MAGAPRGGGGGGGGAGEPGGAERAAGTSRRRGLRACDEEFACPELEALFRGYTLRLEQAATLKALAVLSLLAGALALAELLGAPGPAPGLAKGSHPVHCVLFLALLVVTNVRSLQVPQLQQVGQLALLFSLTFALLCCPFALGGPARGSAGAAGGPATAEQGVWQLLLVTFVSYALLPVRSLLAIGFGLVVAASHLLVTATLVPAKRPRLWRTLGANALLFVGVNMYGVFVRILTERSQRKAFLQARSCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGYGHERNSFLKTHNIETFFIVPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKRRALRTASEKLRNRSSFSTNVVYTTPGTRVNRYISRLLEARQTELEMADLNFFTLKYKHVEREQKYHQLQDEYFTSAVVLTLILAALFGLVYLLIFPQSVVVLLLLVFCICFLVACVLYLHITRVQCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWAWSSKPNSSLVVLSSGGQRTALPTLPCESTHHALLCCLVGTLPLAIFFRVSSLPKMILLSGLTTSYILVLELSGYTRTGGGAVSGRSYEPIVAILLFSCALALHARQVDIRLRLDYLWAAQAEEEREDMEKVKLDNRRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEIIADFDELMEKDFYKDIEKIKTIGSTYMAAVGLAPTSGTKAKKSISSHLSTLADFAIEMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGRIQVTEEVHRLLRRCPYHFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQIRSLGLDRKMCPFGRAGLQGRRPPVCPMPGVSVRAGLPPHSPGQYLPSAAAGKEA

Target ORF information:

RefSeq Version	NM_021116.3
Organism	Homo sapiens(human)
Definition	Homo sapiens adenylate cyclase 1 (ADCY1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021116.3

ORF Insert Sequence:

ATGGCGGGGG CGCCGCGCGG CGGAGGCGGC GGCGGAGGCG GCGCGGGCGA GCCCGGGGGC 
GCCGAGCGGG CGGCCGGGAC AAGCCGCCGG CGCGGGCTCC GGGCGTGCGA CGAGGAGTTC 
GCTTGCCCAG AGCTGGAGGC GCTGTTCCGC GGCTACACGC TGCGGCTGGA GCAGGCGGCC 
ACGCTGAAGG CGCTGGCCGT TCTCAGCCTG CTGGCGGGCG CGCTGGCGCT GGCCGAGCTG 
CTGGGCGCGC CGGGGCCCGC GCCCGGCCTG GCCAAGGGCT CACACCCGGT GCACTGCGTC 
CTCTTCCTGG CGCTGCTCGT GGTAACCAAC GTCCGGTCCC TGCAGGTGCC CCAGCTGCAG 
CAGGTCGGCC AGCTGGCGCT GCTCTTCAGC CTCACCTTCG CGCTGCTCTG CTGTCCTTTC 
GCGCTGGGCG GCCCCGCCCG GGGTTCCGCC GGGGCCGCTG GGGGGCCAGC GACCGCCGAA 
CAAGGGGTTT GGCAGCTCCT TTTGGTCACC TTCGTGTCCT ATGCCTTGCT GCCCGTGCGC 
AGCCTGCTGG CCATAGGCTT TGGGCTCGTG GTGGCTGCGT CGCACTTGCT GGTCACAGCC 
ACCTTGGTCC CCGCCAAGCG CCCACGTCTC TGGAGGACGC TCGGTGCCAA TGCCTTGCTC 
TTCGTCGGTG TGAACATGTA TGGGGTCTTT GTGCGGATTC TGACTGAGCG TTCACAGAGG 
AAGGCGTTCC TGCAGGCCCG GAGCTGCATT GAGGACCGAC TGAGGCTGGA GGATGAGAAC 
GAGAAGCAGG AGCGGCTCCT CATGAGCCTC CTGCCCCGGA ACGTTGCCAT GGAGATGAAG 
GAGGACTTCC TGAAGCCCCC TGAGAGGATT TTCCACAAGA TTTACATCCA GAGGCACGAC 
AATGTGAGCA TCCTGTTTGC TGACATCGTG GGTTTCACGG GCTTGGCATC CCAGTGCACA 
GCCCAGGAGC TGGTGAAACT CCTCAATGAG CTCTTCGGCA AGTTCGATGA ATTAGCCACG 
GAGAACCACT GTCGCCGCAT CAAGATTCTC GGGGACTGCT ACTACTGCGT GTCGGGCCTC 
ACCCAGCCCA AGACTGACCA TGCCCACTGC TGTGTGGAGA TGGGACTCGA CATGATTGAT 
ACCATCACAT CTGTGGCTGA AGCCACCGAG GTGGATCTGA ACATGCGTGT GGGTCTGCAC 
ACGGGCAGGG TCCTCTGTGG TGTCCTGGGC TTGCGCAAGT GGCAGTACGA CGTGTGGTCC 
AATGATGTGA CCTTGGCCAA TGTCATGGAA GCCGCTGGCC TGCCAGGGAA GGTTCATATC 
ACAAAGACGA CCCTAGCGTG CTTGAATGGG GACTACGAGG TAGAACCGGG TTACGGACAT 
GAGAGGAACA GTTTCTTGAA AACTCATAAC ATCGAAACCT TTTTTATTGT GCCATCCCAT 
CGCCGAAAGA TATTTCCAGG CCTGATTCTC TCAGATATAA AACCGGCCAA AAGGATGAAG 
TTCAAGACTG TCTGCTACCT GCTGGTGCAG CTCATGCACT GCCGGAAAAT GTTCAAGGCC 
GAGATCCCCT TCTCCAATGT CATGACCTGC GAGGACGATG ACAAGCGGAG GGCATTAAGA 
ACAGCCTCGG AAAAACTCAG AAACCGCTCA TCTTTTTCTA CCAACGTTGT CTACACCACC 
CCGGGCACTC GCGTCAACAG GTACATCAGC CGCCTCTTAG AAGCCCGCCA GACAGAGCTG 
GAGATGGCAG ACCTGAACTT CTTTACCCTG AAGTACAAAC ATGTCGAACG GGAGCAAAAG 
TACCACCAGC TTCAGGACGA GTATTTCACC AGCGCCGTTG TCCTCACCCT CATCCTGGCT 
GCCTTATTTG GCCTTGTCTA CCTTCTAATA TTCCCACAGA GTGTGGTCGT CCTGCTCCTG 
CTAGTATTCT GCATCTGCTT CCTGGTGGCC TGTGTCCTGT ACCTGCACAT CACCCGGGTC 
CAGTGTTTTC CAGGGTGCCT GACGATTCAG ATTCGCACTG TCCTGTGTAT TTTCATAGTG 
GTCTTAATCT ACTCAGTAGC CCAAGGTTGT GTGGTGGGCT GCCTGCCTTG GGCCTGGAGC 
TCCAAGCCCA ACAGTTCCCT GGTGGTCCTT TCGTCTGGGG GCCAGCGCAC AGCCCTGCCC 
ACCCTGCCCT GCGAGTCTAC ACACCATGCC CTGCTCTGCT GCCTGGTGGG CACCCTCCCG 
CTAGCCATAT TTTTCCGGGT GTCCTCCTTG CCAAAAATGA TCCTGCTCTC CGGGCTCACC 
ACGTCCTACA TCCTCGTTCT GGAGCTCAGC GGATACACCA GGACTGGGGG TGGTGCCGTC 
TCCGGGCGCA GCTACGAGCC GATTGTGGCC ATCCTGCTCT TCTCCTGTGC GCTGGCCCTG 
CATGCCAGGC AGGTGGACAT CAGGCTGAGG CTGGACTACC TCTGGGCCGC ACAGGCAGAG 
GAGGAGCGAG AGGACATGGA GAAGGTGAAG CTGGACAACA GGCGCATCCT CTTCAACCTC 
CTGCCGGCCC ACGTCGCCCA GCACTTCCTC ATGTCCAACC CTCGGAACAT GGACCTCTAC 
TACCAGTCCT ACTCCCAGGT GGGCGTCATG TTTGCCTCCA TCCCCAACTT CAATGACTTC 
TACATCGAGC TGGACGGCAA CAACATGGGG GTGGAGTGTC TGCGGCTTCT CAACGAGATC 
ATCGCCGACT TTGACGAGCT CATGGAAAAA GACTTTTACA AGGACATAGA GAAGATCAAG 
ACCATCGGGA GCACCTACAT GGCCGCTGTG GGGCTAGCGC CCACCTCGGG GACCAAGGCT 
AAGAAGTCCA TCTCCTCCCA CCTGAGCACG CTGGCGGACT TTGCCATTGA GATGTTTGAC 
GTTCTGGATG AAATCAACTA CCAGTCTTAC AACGACTTTG TCCTCCGAGT TGGCATCAAT 
GTTGGCCCTG TGGTGGCTGG AGTGATTGGC GCTCGCAGGC CCCAGTACGA CATCTGGGGA 
AACACAGTCA ACGTGGCCAG TCGGATGGAT AGCACAGGGG TCCAGGGCAG AATCCAGGTG 
ACTGAGGAAG TCCACCGGCT GCTGAGAAGG TGCCCCTACC ACTTTGTGTG CCGAGGCAAA 
GTCAGTGTCA AGGGCAAAGG CGAGATGTTG ACATACTTTC TAGAAGGCAG GACTGATGGA 
AACGGCTCCC AAATCAGGTC CCTGGGCTTG GATCGGAAAA TGTGTCCATT TGGGAGAGCT 
GGCCTTCAGG GCAGACGTCC CCCCGTGTGC CCCATGCCTG GCGTCTCAGT CAGGGCTGGG 
CTCCCTCCAC ACTCCCCAGG CCAGTACCTG CCCTCTGCAG CAGCTGGGAA GGAGGCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADCY1 ( NM_021116.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_066939.1 Homo sapiens adenylate cyclase 1 (ADCY1), transcript variant 1, mRNA.

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CloneID	OHu30550
Clone ID Related Accession (Same CDS sequence)	NM_021116.2 , NM_021116.3 , NM_021116.4
Accession Version	NM_021116.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3360bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-02
Organism	Homo sapiens(human)
Product	adenylate cyclase type 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC069008.6, AF497515.1, AB209496.1 and AC091439.5. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_021116.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB209496.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144120 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000297323.12/ ENSP00000297323.7 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGGGG CGCCGCGCGG CGGAGGCGGC GGCGGAGGCG GCGCGGGCGA GCCCGGGGGC 
GCCGAGCGGG CGGCCGGGAC AAGCCGCCGG CGCGGGCTCC GGGCGTGCGA CGAGGAGTTC 
GCTTGCCCAG AGCTGGAGGC GCTGTTCCGC GGCTACACGC TGCGGCTGGA GCAGGCGGCC 
ACGCTGAAGG CGCTGGCCGT TCTCAGCCTG CTGGCGGGCG CGCTGGCGCT GGCCGAGCTG 
CTGGGCGCGC CGGGGCCCGC GCCCGGCCTG GCCAAGGGCT CACACCCGGT GCACTGCGTC 
CTCTTCCTGG CGCTGCTCGT GGTAACCAAC GTCCGGTCCC TGCAGGTGCC CCAGCTGCAG 
CAGGTCGGCC AGCTGGCGCT GCTCTTCAGC CTCACCTTCG CGCTGCTCTG CTGTCCTTTC 
GCGCTGGGCG GCCCCGCCCG GGGTTCCGCC GGGGCCGCTG GGGGGCCAGC GACCGCCGAA 
CAAGGGGTTT GGCAGCTCCT TTTGGTCACC TTCGTGTCCT ATGCCTTGCT GCCCGTGCGC 
AGCCTGCTGG CCATAGGCTT TGGGCTCGTG GTGGCTGCGT CGCACTTGCT GGTCACAGCC 
ACCTTGGTCC CCGCCAAGCG CCCACGTCTC TGGAGGACGC TCGGTGCCAA TGCCTTGCTC 
TTCGTCGGTG TGAACATGTA TGGGGTCTTT GTGCGGATTC TGACTGAGCG TTCACAGAGG 
AAGGCGTTCC TGCAGGCCCG GAGCTGCATT GAGGACCGAC TGAGGCTGGA GGATGAGAAC 
GAGAAGCAGG AGCGGCTCCT CATGAGCCTC CTGCCCCGGA ACGTTGCCAT GGAGATGAAG 
GAGGACTTCC TGAAGCCCCC TGAGAGGATT TTCCACAAGA TTTACATCCA GAGGCACGAC 
AATGTGAGCA TCCTGTTTGC TGACATCGTG GGTTTCACGG GCTTGGCATC CCAGTGCACA 
GCCCAGGAGC TGGTGAAACT CCTCAATGAG CTCTTCGGCA AGTTCGATGA ATTAGCCACG 
GAGAACCACT GTCGCCGCAT CAAGATTCTC GGGGACTGCT ACTACTGCGT GTCGGGCCTC 
ACCCAGCCCA AGACTGACCA TGCCCACTGC TGTGTGGAGA TGGGACTCGA CATGATTGAT 
ACCATCACAT CTGTGGCTGA AGCCACCGAG GTGGATCTGA ACATGCGTGT GGGTCTGCAC 
ACGGGCAGGG TCCTCTGTGG TGTCCTGGGC TTGCGCAAGT GGCAGTACGA CGTGTGGTCC 
AATGATGTGA CCTTGGCCAA TGTCATGGAA GCCGCTGGCC TGCCAGGGAA GGTTCATATC 
ACAAAGACGA CCCTAGCGTG CTTGAATGGG GACTACGAGG TAGAACCGGG TTACGGACAT 
GAGAGGAACA GTTTCTTGAA AACTCATAAC ATCGAAACCT TTTTTATTGT GCCATCCCAT 
CGCCGAAAGA TATTTCCAGG CCTGATTCTC TCAGATATAA AACCGGCCAA AAGGATGAAG 
TTCAAGACTG TCTGCTACCT GCTGGTGCAG CTCATGCACT GCCGGAAAAT GTTCAAGGCC 
GAGATCCCCT TCTCCAATGT CATGACCTGC GAGGACGATG ACAAGCGGAG GGCATTAAGA 
ACAGCCTCGG AAAAACTCAG AAACCGCTCA TCTTTTTCTA CCAACGTTGT CTACACCACC 
CCGGGCACTC GCGTCAACAG GTACATCAGC CGCCTCTTAG AAGCCCGCCA GACAGAGCTG 
GAGATGGCAG ACCTGAACTT CTTTACCCTG AAGTACAAAC ATGTCGAACG GGAGCAAAAG 
TACCACCAGC TTCAGGACGA GTATTTCACC AGCGCCGTTG TCCTCACCCT CATCCTGGCT 
GCCTTATTTG GCCTTGTCTA CCTTCTAATA TTCCCACAGA GTGTGGTCGT CCTGCTCCTG 
CTAGTATTCT GCATCTGCTT CCTGGTGGCC TGTGTCCTGT ACCTGCACAT CACCCGGGTC 
CAGTGTTTTC CAGGGTGCCT GACGATTCAG ATTCGCACTG TCCTGTGTAT TTTCATAGTG 
GTCTTAATCT ACTCAGTAGC CCAAGGTTGT GTGGTGGGCT GCCTGCCTTG GGCCTGGAGC 
TCCAAGCCCA ACAGTTCCCT GGTGGTCCTT TCGTCTGGGG GCCAGCGCAC AGCCCTGCCC 
ACCCTGCCCT GCGAGTCTAC ACACCATGCC CTGCTCTGCT GCCTGGTGGG CACCCTCCCG 
CTAGCCATAT TTTTCCGGGT GTCCTCCTTG CCAAAAATGA TCCTGCTCTC CGGGCTCACC 
ACGTCCTACA TCCTCGTTCT GGAGCTCAGC GGATACACCA GGACTGGGGG TGGTGCCGTC 
TCCGGGCGCA GCTACGAGCC GATTGTGGCC ATCCTGCTCT TCTCCTGTGC GCTGGCCCTG 
CATGCCAGGC AGGTGGACAT CAGGCTGAGG CTGGACTACC TCTGGGCCGC ACAGGCAGAG 
GAGGAGCGAG AGGACATGGA GAAGGTGAAG CTGGACAACA GGCGCATCCT CTTCAACCTC 
CTGCCGGCCC ACGTCGCCCA GCACTTCCTC ATGTCCAACC CTCGGAACAT GGACCTCTAC 
TACCAGTCCT ACTCCCAGGT GGGCGTCATG TTTGCCTCCA TCCCCAACTT CAATGACTTC 
TACATCGAGC TGGACGGCAA CAACATGGGG GTGGAGTGTC TGCGGCTTCT CAACGAGATC 
ATCGCCGACT TTGACGAGCT CATGGAAAAA GACTTTTACA AGGACATAGA GAAGATCAAG 
ACCATCGGGA GCACCTACAT GGCCGCTGTG GGGCTAGCGC CCACCTCGGG GACCAAGGCT 
AAGAAGTCCA TCTCCTCCCA CCTGAGCACG CTGGCGGACT TTGCCATTGA GATGTTTGAC 
GTTCTGGATG AAATCAACTA CCAGTCTTAC AACGACTTTG TCCTCCGAGT TGGCATCAAT 
GTTGGCCCTG TGGTGGCTGG AGTGATTGGC GCTCGCAGGC CCCAGTACGA CATCTGGGGA 
AACACAGTCA ACGTGGCCAG TCGGATGGAT AGCACAGGGG TCCAGGGCAG AATCCAGGTG 
ACTGAGGAAG TCCACCGGCT GCTGAGAAGG TGCCCCTACC ACTTTGTGTG CCGAGGCAAA 
GTCAGTGTCA AGGGCAAAGG CGAGATGTTG ACATACTTTC TAGAAGGCAG GACTGATGGA 
AACGGCTCCC AAATCAGGTC CCTGGGCTTG GATCGGAAAA TGTGTCCATT TGGGAGAGCT 
GGCCTTCAGG GCAGACGTCC CCCCGTGTGC CCCATGCCTG GCGTCTCAGT CAGGGCTGGG 
CTCCCTCCAC ACTCCCCAGG CCAGTACCTG CCCTCTGCAG CAGCTGGGAA GGAGGCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_066939.1
CDS	177..3536
Translation	MAGAPRGGGGGGGGAGEPGGAERAAGTSRRRGLRACDEEFACPELEALFRGYTLRLEQAATLKALAVLSLLAGALALAELLGAPGPAPGLAKGSHPVHCVLFLALLVVTNVRSLQVPQLQQVGQLALLFSLTFALLCCPFALGGPARGSAGAAGGPATAEQGVWQLLLVTFVSYALLPVRSLLAIGFGLVVAASHLLVTATLVPAKRPRLWRTLGANALLFVGVNMYGVFVRILTERSQRKAFLQARSCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGYGHERNSFLKTHNIETFFIVPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKRRALRTASEKLRNRSSFSTNVVYTTPGTRVNRYISRLLEARQTELEMADLNFFTLKYKHVEREQKYHQLQDEYFTSAVVLTLILAALFGLVYLLIFPQSVVVLLLLVFCICFLVACVLYLHITRVQCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWAWSSKPNSSLVVLSSGGQRTALPTLPCESTHHALLCCLVGTLPLAIFFRVSSLPKMILLSGLTTSYILVLELSGYTRTGGGAVSGRSYEPIVAILLFSCALALHARQVDIRLRLDYLWAAQAEEEREDMEKVKLDNRRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEIIADFDELMEKDFYKDIEKIKTIGSTYMAAVGLAPTSGTKAKKSISSHLSTLADFAIEMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGRIQVTEEVHRLLRRCPYHFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQIRSLGLDRKMCPFGRAGLQGRRPPVCPMPGVSVRAGLPPHSPGQYLPSAAAGKEA

Target ORF information:

RefSeq Version	NM_021116.4
Organism	Homo sapiens(human)
Definition	Homo sapiens adenylate cyclase 1 (ADCY1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021116.4

ORF Insert Sequence:

ATGGCGGGGG CGCCGCGCGG CGGAGGCGGC GGCGGAGGCG GCGCGGGCGA GCCCGGGGGC 
GCCGAGCGGG CGGCCGGGAC AAGCCGCCGG CGCGGGCTCC GGGCGTGCGA CGAGGAGTTC 
GCTTGCCCAG AGCTGGAGGC GCTGTTCCGC GGCTACACGC TGCGGCTGGA GCAGGCGGCC 
ACGCTGAAGG CGCTGGCCGT TCTCAGCCTG CTGGCGGGCG CGCTGGCGCT GGCCGAGCTG 
CTGGGCGCGC CGGGGCCCGC GCCCGGCCTG GCCAAGGGCT CACACCCGGT GCACTGCGTC 
CTCTTCCTGG CGCTGCTCGT GGTAACCAAC GTCCGGTCCC TGCAGGTGCC CCAGCTGCAG 
CAGGTCGGCC AGCTGGCGCT GCTCTTCAGC CTCACCTTCG CGCTGCTCTG CTGTCCTTTC 
GCGCTGGGCG GCCCCGCCCG GGGTTCCGCC GGGGCCGCTG GGGGGCCAGC GACCGCCGAA 
CAAGGGGTTT GGCAGCTCCT TTTGGTCACC TTCGTGTCCT ATGCCTTGCT GCCCGTGCGC 
AGCCTGCTGG CCATAGGCTT TGGGCTCGTG GTGGCTGCGT CGCACTTGCT GGTCACAGCC 
ACCTTGGTCC CCGCCAAGCG CCCACGTCTC TGGAGGACGC TCGGTGCCAA TGCCTTGCTC 
TTCGTCGGTG TGAACATGTA TGGGGTCTTT GTGCGGATTC TGACTGAGCG TTCACAGAGG 
AAGGCGTTCC TGCAGGCCCG GAGCTGCATT GAGGACCGAC TGAGGCTGGA GGATGAGAAC 
GAGAAGCAGG AGCGGCTCCT CATGAGCCTC CTGCCCCGGA ACGTTGCCAT GGAGATGAAG 
GAGGACTTCC TGAAGCCCCC TGAGAGGATT TTCCACAAGA TTTACATCCA GAGGCACGAC 
AATGTGAGCA TCCTGTTTGC TGACATCGTG GGTTTCACGG GCTTGGCATC CCAGTGCACA 
GCCCAGGAGC TGGTGAAACT CCTCAATGAG CTCTTCGGCA AGTTCGATGA ATTAGCCACG 
GAGAACCACT GTCGCCGCAT CAAGATTCTC GGGGACTGCT ACTACTGCGT GTCGGGCCTC 
ACCCAGCCCA AGACTGACCA TGCCCACTGC TGTGTGGAGA TGGGACTCGA CATGATTGAT 
ACCATCACAT CTGTGGCTGA AGCCACCGAG GTGGATCTGA ACATGCGTGT GGGTCTGCAC 
ACGGGCAGGG TCCTCTGTGG TGTCCTGGGC TTGCGCAAGT GGCAGTACGA CGTGTGGTCC 
AATGATGTGA CCTTGGCCAA TGTCATGGAA GCCGCTGGCC TGCCAGGGAA GGTTCATATC 
ACAAAGACGA CCCTAGCGTG CTTGAATGGG GACTACGAGG TAGAACCGGG TTACGGACAT 
GAGAGGAACA GTTTCTTGAA AACTCATAAC ATCGAAACCT TTTTTATTGT GCCATCCCAT 
CGCCGAAAGA TATTTCCAGG CCTGATTCTC TCAGATATAA AACCGGCCAA AAGGATGAAG 
TTCAAGACTG TCTGCTACCT GCTGGTGCAG CTCATGCACT GCCGGAAAAT GTTCAAGGCC 
GAGATCCCCT TCTCCAATGT CATGACCTGC GAGGACGATG ACAAGCGGAG GGCATTAAGA 
ACAGCCTCGG AAAAACTCAG AAACCGCTCA TCTTTTTCTA CCAACGTTGT CTACACCACC 
CCGGGCACTC GCGTCAACAG GTACATCAGC CGCCTCTTAG AAGCCCGCCA GACAGAGCTG 
GAGATGGCAG ACCTGAACTT CTTTACCCTG AAGTACAAAC ATGTCGAACG GGAGCAAAAG 
TACCACCAGC TTCAGGACGA GTATTTCACC AGCGCCGTTG TCCTCACCCT CATCCTGGCT 
GCCTTATTTG GCCTTGTCTA CCTTCTAATA TTCCCACAGA GTGTGGTCGT CCTGCTCCTG 
CTAGTATTCT GCATCTGCTT CCTGGTGGCC TGTGTCCTGT ACCTGCACAT CACCCGGGTC 
CAGTGTTTTC CAGGGTGCCT GACGATTCAG ATTCGCACTG TCCTGTGTAT TTTCATAGTG 
GTCTTAATCT ACTCAGTAGC CCAAGGTTGT GTGGTGGGCT GCCTGCCTTG GGCCTGGAGC 
TCCAAGCCCA ACAGTTCCCT GGTGGTCCTT TCGTCTGGGG GCCAGCGCAC AGCCCTGCCC 
ACCCTGCCCT GCGAGTCTAC ACACCATGCC CTGCTCTGCT GCCTGGTGGG CACCCTCCCG 
CTAGCCATAT TTTTCCGGGT GTCCTCCTTG CCAAAAATGA TCCTGCTCTC CGGGCTCACC 
ACGTCCTACA TCCTCGTTCT GGAGCTCAGC GGATACACCA GGACTGGGGG TGGTGCCGTC 
TCCGGGCGCA GCTACGAGCC GATTGTGGCC ATCCTGCTCT TCTCCTGTGC GCTGGCCCTG 
CATGCCAGGC AGGTGGACAT CAGGCTGAGG CTGGACTACC TCTGGGCCGC ACAGGCAGAG 
GAGGAGCGAG AGGACATGGA GAAGGTGAAG CTGGACAACA GGCGCATCCT CTTCAACCTC 
CTGCCGGCCC ACGTCGCCCA GCACTTCCTC ATGTCCAACC CTCGGAACAT GGACCTCTAC 
TACCAGTCCT ACTCCCAGGT GGGCGTCATG TTTGCCTCCA TCCCCAACTT CAATGACTTC 
TACATCGAGC TGGACGGCAA CAACATGGGG GTGGAGTGTC TGCGGCTTCT CAACGAGATC 
ATCGCCGACT TTGACGAGCT CATGGAAAAA GACTTTTACA AGGACATAGA GAAGATCAAG 
ACCATCGGGA GCACCTACAT GGCCGCTGTG GGGCTAGCGC CCACCTCGGG GACCAAGGCT 
AAGAAGTCCA TCTCCTCCCA CCTGAGCACG CTGGCGGACT TTGCCATTGA GATGTTTGAC 
GTTCTGGATG AAATCAACTA CCAGTCTTAC AACGACTTTG TCCTCCGAGT TGGCATCAAT 
GTTGGCCCTG TGGTGGCTGG AGTGATTGGC GCTCGCAGGC CCCAGTACGA CATCTGGGGA 
AACACAGTCA ACGTGGCCAG TCGGATGGAT AGCACAGGGG TCCAGGGCAG AATCCAGGTG 
ACTGAGGAAG TCCACCGGCT GCTGAGAAGG TGCCCCTACC ACTTTGTGTG CCGAGGCAAA 
GTCAGTGTCA AGGGCAAAGG CGAGATGTTG ACATACTTTC TAGAAGGCAG GACTGATGGA 
AACGGCTCCC AAATCAGGTC CCTGGGCTTG GATCGGAAAA TGTGTCCATT TGGGAGAGCT 
GGCCTTCAGG GCAGACGTCC CCCCGTGTGC CCCATGCCTG GCGTCTCAGT CAGGGCTGGG 
CTCCCTCCAC ACTCCCCAGG CCAGTACCTG CCCTCTGCAG CAGCTGGGAA GGAGGCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADCY1 ( NM_001281768.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001268697.1 Homo sapiens adenylate cyclase 1 (ADCY1), transcript variant 2, mRNA.

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CloneID	OHu00606
Clone ID Related Accession (Same CDS sequence)	NM_001281768.1
Accession Version	NM_001281768.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1017bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-01
Organism	Homo sapiens(human)
Product	adenylate cyclase type 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC041473.1. Transcript Variant: This variant (2) differs in the 5' and 3' UTR and has multiple differences in the coding region compared to variant 1. The encoded isoform (2) has a shorter N-terminus and a distinct C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC041473.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTATGGGG TCTTTGTGCG GATTCTGACT GAGCGTTCAC AGAGGAAGGC GTTCCTGCAG 
GCCCGGAGCT GCATTGAGGA CCGACTGAGG CTGGAGGATG AGAACGAGAA GCAGGAGCGG 
CTCCTCATGA GCCTCCTGCC CCGGAACGTT GCCATGGAGA TGAAGGAGGA CTTCCTGAAG 
CCCCCTGAGA GGATTTTCCA CAAGATTTAC ATCCAGAGGC ACGACAATGT GAGCATCCTG 
TTTGCTGACA TCGTGGGTTT CACGGGCTTG GCATCCCAGT GCACAGCCCA GGAGCTGGTG 
AAACTCCTCA ATGAGCTCTT CGGCAAGTTC GATGAATTAG CCACGGAGAA CCACTGTCGC 
CGCATCAAGA TTCTCGGGGA CTGCTACTAC TGCGTGTCGG GCCTCACCCA GCCCAAGACT 
GACCATGCCC ACTGCTGTGT GGAGATGGGA CTCGACATGA TTGATACCAT CACATCTGTG 
GCTGAAGCCA CCGAGGTGGA TCTGAACATG CGTGTGGGTC TGCACACGGG CAGGGTCCTC 
TGTGGTGTCC TGGGCTTGCG CAAGTGGCAG TACGACGTGT GGTCCAATGA TGTGACCTTG 
GCCAATGTCA TGGAAGCCGC TGGCCTGCCA GGGAAGGTTC ATATCACAAA GACGACCCTA 
GCGTGCTTGA ATGGGGACTA CGAGGTAGAA CCGGGTTACG GACATGAGAG GAACAGTTTC 
TTGAAAACTC ATAACATCGA AACCTTTTTT ATTGTGCCAT CCCATCGCCG AAAGATATTT 
CCAGGCCTGA TTCTCTCAGA TATAAAACCG GCCAAAAGGA TGAAGTTCAA GACTGTCTGC 
TACCTGCTGG TGCAGCTCAT GCACTGCCGG AAAATGTTCA AGGCCGAGAT CCCCTTCTCC 
AATGTCATGA CCTGCGAGGA CGATGACAAG GTTCAGATCC ATCCCTCACT GAGTGGCCTG 
GATGTCCTCC TGGGGTTTTG GTCTCCCACC CTGCAACGGG GACGACTGTG CACGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001268697.1
CDS	380..1396
Translation	MYGVFVRILTERSQRKAFLQARSCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGYGHERNSFLKTHNIETFFIVPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKVQIHPSLSGLDVLLGFWSPTLQRGRLCT

Target ORF information:

RefSeq Version	NM_001281768.1
Organism	Homo sapiens(human)
Definition	Homo sapiens adenylate cyclase 1 (ADCY1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001281768.1

ORF Insert Sequence:

ATGTATGGGG TCTTTGTGCG GATTCTGACT GAGCGTTCAC AGAGGAAGGC GTTCCTGCAG 
GCCCGGAGCT GCATTGAGGA CCGACTGAGG CTGGAGGATG AGAACGAGAA GCAGGAGCGG 
CTCCTCATGA GCCTCCTGCC CCGGAACGTT GCCATGGAGA TGAAGGAGGA CTTCCTGAAG 
CCCCCTGAGA GGATTTTCCA CAAGATTTAC ATCCAGAGGC ACGACAATGT GAGCATCCTG 
TTTGCTGACA TCGTGGGTTT CACGGGCTTG GCATCCCAGT GCACAGCCCA GGAGCTGGTG 
AAACTCCTCA ATGAGCTCTT CGGCAAGTTC GATGAATTAG CCACGGAGAA CCACTGTCGC 
CGCATCAAGA TTCTCGGGGA CTGCTACTAC TGCGTGTCGG GCCTCACCCA GCCCAAGACT 
GACCATGCCC ACTGCTGTGT GGAGATGGGA CTCGACATGA TTGATACCAT CACATCTGTG 
GCTGAAGCCA CCGAGGTGGA TCTGAACATG CGTGTGGGTC TGCACACGGG CAGGGTCCTC 
TGTGGTGTCC TGGGCTTGCG CAAGTGGCAG TACGACGTGT GGTCCAATGA TGTGACCTTG 
GCCAATGTCA TGGAAGCCGC TGGCCTGCCA GGGAAGGTTC ATATCACAAA GACGACCCTA 
GCGTGCTTGA ATGGGGACTA CGAGGTAGAA CCGGGTTACG GACATGAGAG GAACAGTTTC 
TTGAAAACTC ATAACATCGA AACCTTTTTT ATTGTGCCAT CCCATCGCCG AAAGATATTT 
CCAGGCCTGA TTCTCTCAGA TATAAAACCG GCCAAAAGGA TGAAGTTCAA GACTGTCTGC 
TACCTGCTGG TGCAGCTCAT GCACTGCCGG AAAATGTTCA AGGCCGAGAT CCCCTTCTCC 
AATGTCATGA CCTGCGAGGA CGATGACAAG GTTCAGATCC ATCCCTCACT GAGTGGCCTG 
GATGTCCTCC TGGGGTTTTG GTCTCCCACC CTGCAACGGG GACGACTGTG CACGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADCY1 ( XM_005249584.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005249641.1 Homo sapiens adenylate cyclase 1 (ADCY1), transcript variant X1, mRNA.

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CloneID	OHu41062
Clone ID Related Accession (Same CDS sequence)	XM_005249584.3
Accession Version	XM_005249584.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2940bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	adenylate cyclase type 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005249584.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGGGG CGCCGCGCGG CGGAGGCGGC GGCGGAGGCG GCGCGGGCGA GCCCGGGGGC 
GCCGAGCGGG CGGCCGGGAC AAGCCGCCGG CGCGGGCTCC GGGCGTGCGA CGAGGAGTTC 
GCTTGCCCAG AGCTGGAGGC GCTGTTCCGC GGCTACACGC TGCGGCTGGA GCAGGCGGCC 
ACGCTGAAGG CGCTGGCCGT TCTCAGCCTG CTGGCGGGCG CGCTGGCGCT GGCCGAGCTG 
CTGGGCGCGC CGGGGCCCGC GCCCGGCCTG GCCAAGGGCT CACACCCGGT GCACTGCGTC 
CTCTTCCTGG CGCTGCTCGT GGTAACCAAC GTCCGGTCCC TGCAGGTGCC CCAGCTGCAG 
CAGGTCGGCC AGCTGGCGCT GCTCTTCAGC CTCACCTTCG CGCTGCTCTG CTGTCCTTTC 
GCGCTGGGCG GCCCCGCCCG GGGTTCCGCC GGGGCCGCTG GGGGGCCAGC GACCGCCGAA 
CAAGGGGTTT GGCAGCTCCT TTTGGTCACC TTCGTGTCCT ATGCCTTGCT GCCCGTGCGC 
AGCCTGCTGG CCATAGGCTT TGGGCTCGTG GTGGCTGCGT CGCACTTGCT GGTCACAGCC 
ACCTTGGTCC CCGCCAAGCG CCCACGTCTC TGGAGGACGC TCGGTGCCAA TGCCTTGCTC 
TTCGTCGGTG TGAACATGTA TGGGGTCTTT GTGCGGATTC TGACTGAGCG TTCACAGAGG 
AAGGCGTTCC TGCAGGCCCG GAGCTGCATT GAGGACCGAC TGAGGCTGGA GGATGAGAAC 
GAGAAGCAGG AGCGGCTCCT CATGAGCCTC CTGCCCCGGA ACGTTGCCAT GGAGATGAAG 
GAGGACTTCC TGAAGCCCCC TGAGAGGATT TTCCACAAGA TTTACATCCA GAGGCACGAC 
AATGTGAGCA TCCTGTTTGC TGACATCGTG GGTTTCACGG GCTTGGCATC CCAGTGCACA 
GCCCAGGAGC TGGTGAAACT CCTCAATGAG CTCTTCGGCA AGTTCGATGA ATTAGCCACG 
GAGAACCACT GTCGCCGCAT CAAGATTCTC GGGGACTGCT ACTACTGCGT GTCGGGCCTC 
ACCCAGCCCA AGACTGACCA TGCCCACTGC TGTGTGGAGA TGGGACTCGA CATGATTGAT 
ACCATCACAT CTGTGGCTGA AGCCACCGAG GTGGATCTGA ACATGCGTGT GGGTCTGCAC 
ACGGGCAGGG TCCTCTGTGG TGTCCTGGGC TTGCGCAAGT GGCAGTACGA CGTGTGGTCC 
AATGATGTGA CCTTGGCCAA TGTCATGGAA GCCGCTGGCC TGCCAGGGAA GGTTCATATC 
ACAAAGACGA CCCTAGCGTG CTTGAATGGG GACTACGAGG TAGAACCGGG TTACGGACAT 
GAGAGGAACA GTTTCTTGAA AACTCATAAC ATCGAAACCT TTTTTATTGT GCCATCCCAT 
CGCCGAAAGA TATTTCCAGG CCTGATTCTC TCAGATATAA AACCGGCCAA AAGGATGAAG 
TTCAAGACTG TCTGCTACCT GCTGGTGCAG CTCATGCACT GCCGGAAAAT GTTCAAGGCC 
GAGATCCCCT TCTCCAATGT CATGACCTGC GAGGACGATG ACAAGCGGAG GGCATTAAGA 
ACAGCCTCGG AAAAACTCAG AAACCGCTCA TCTTTTTCTA CCAACGTTGT CTACACCACC 
CCGGGCACTC GCGTCAACAG GTACATCAGC CGCCTCTTAG AAGCCCGCCA GACAGAGCTG 
GAGATGGCAG ACCTGAACTT CTTTACCCTG AAGTACAAAC ATGTCGAACG GGAGCAAAAG 
TACCACCAGC TTCAGGACGA GTATTTCACC AGCGCCGTTG TCCTCACCCT CATCCTGGCT 
GCCTTATTTG GCCTTGTCTA CCTTCTAATA TTCCCACAGA GTGTGGTCGT CCTGCTCCTG 
CTAGTATTCT GCATCTGCTT CCTGGTGGCC TGTGTCCTGT ACCTGCACAT CACCCGGGTC 
CAGTGTTTTC CAGGGTGCCT GACGATTCAG ATTCGCACTG TCCTGTGTAT TTTCATAGTG 
GTCTTAATCT ACTCAGTAGC CCAAGGTTGT GTGGTGGGCT GCCTGCCTTG GGCCTGGAGC 
TCCAAGCCCA ACAGTTCCCT GGTGGTCCTT TCGTCTGGGG GCCAGCGCAC AGCCCTGCCC 
ACCCTGCCCT GCGAGTCTAC ACACCATGCC CTGCTCTGCT GCCTGGTGGG CACCCTCCCG 
CTAGCCATAT TTTTCCGGGT GTCCTCCTTG CCAAAAATGA TCCTGCTCTC CGGGCTCACC 
ACGTCCTACA TCCTCGTTCT GGAGCTCAGC GGATACACCA GGACTGGGGG TGGTGCCGTC 
TCCGGGCGCA GCTACGAGCC GATTGTGGCC ATCCTGCTCT TCTCCTGTGC GCTGGCCCTG 
CATGCCAGGC AGGTGGACAT CAGGCTGAGG CTGGACTACC TCTGGGCCGC ACAGGCAGAG 
GAGGAGCGAG AGGACATGGA GAAGGTGAAG CTGGACAACA GGCGCATCCT CTTCAACCTC 
CTGCCGGCCC ACGTCGCCCA GCACTTCCTC ATGTCCAACC CTCGGAACAT GGACCTCTAC 
TACCAGTCCT ACTCCCAGGT GGGCGTCATG TTTGCCTCCA TCCCCAACTT CAATGACTTC 
TACATCGAGC TGGACGGCAA CAACATGGGG GTGGAGTGTC TGCGGCTTCT CAACGAGATC 
ATCGCCGACT TTGACGAGCT CATGGAAAAA GACTTTTACA AGGACATAGA GAAGATCAAG 
ACCATCGGGA GCACCTACAT GGCCGCTGTG GGGCTAGCGC CCACCTCGGG GACCAAGGCT 
AAGAAGTCCA TCTCCTCCCA CCTGAGCACG CTGGCGGACT TTGCCATTGA GATGTTTGAC 
GTTCTGGATG AAATCAACTA CCAGTCTTAC AACGACTTTG TCCTCCGAGT TGGTGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005249641.1
CDS	17..2956
Translation	MAGAPRGGGGGGGGAGEPGGAERAAGTSRRRGLRACDEEFACPELEALFRGYTLRLEQAATLKALAVLSLLAGALALAELLGAPGPAPGLAKGSHPVHCVLFLALLVVTNVRSLQVPQLQQVGQLALLFSLTFALLCCPFALGGPARGSAGAAGGPATAEQGVWQLLLVTFVSYALLPVRSLLAIGFGLVVAASHLLVTATLVPAKRPRLWRTLGANALLFVGVNMYGVFVRILTERSQRKAFLQARSCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGYGHERNSFLKTHNIETFFIVPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKRRALRTASEKLRNRSSFSTNVVYTTPGTRVNRYISRLLEARQTELEMADLNFFTLKYKHVEREQKYHQLQDEYFTSAVVLTLILAALFGLVYLLIFPQSVVVLLLLVFCICFLVACVLYLHITRVQCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWAWSSKPNSSLVVLSSGGQRTALPTLPCESTHHALLCCLVGTLPLAIFFRVSSLPKMILLSGLTTSYILVLELSGYTRTGGGAVSGRSYEPIVAILLFSCALALHARQVDIRLRLDYLWAAQAEEEREDMEKVKLDNRRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEIIADFDELMEKDFYKDIEKIKTIGSTYMAAVGLAPTSGTKAKKSISSHLSTLADFAIEMFDVLDEINYQSYNDFVLRVGD

Target ORF information:

RefSeq Version	XM_005249584.3
Organism	Homo sapiens(human)
Definition	Homo sapiens adenylate cyclase 1 (ADCY1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005249584.3

ORF Insert Sequence:

ATGGCGGGGG CGCCGCGCGG CGGAGGCGGC GGCGGAGGCG GCGCGGGCGA GCCCGGGGGC 
GCCGAGCGGG CGGCCGGGAC AAGCCGCCGG CGCGGGCTCC GGGCGTGCGA CGAGGAGTTC 
GCTTGCCCAG AGCTGGAGGC GCTGTTCCGC GGCTACACGC TGCGGCTGGA GCAGGCGGCC 
ACGCTGAAGG CGCTGGCCGT TCTCAGCCTG CTGGCGGGCG CGCTGGCGCT GGCCGAGCTG 
CTGGGCGCGC CGGGGCCCGC GCCCGGCCTG GCCAAGGGCT CACACCCGGT GCACTGCGTC 
CTCTTCCTGG CGCTGCTCGT GGTAACCAAC GTCCGGTCCC TGCAGGTGCC CCAGCTGCAG 
CAGGTCGGCC AGCTGGCGCT GCTCTTCAGC CTCACCTTCG CGCTGCTCTG CTGTCCTTTC 
GCGCTGGGCG GCCCCGCCCG GGGTTCCGCC GGGGCCGCTG GGGGGCCAGC GACCGCCGAA 
CAAGGGGTTT GGCAGCTCCT TTTGGTCACC TTCGTGTCCT ATGCCTTGCT GCCCGTGCGC 
AGCCTGCTGG CCATAGGCTT TGGGCTCGTG GTGGCTGCGT CGCACTTGCT GGTCACAGCC 
ACCTTGGTCC CCGCCAAGCG CCCACGTCTC TGGAGGACGC TCGGTGCCAA TGCCTTGCTC 
TTCGTCGGTG TGAACATGTA TGGGGTCTTT GTGCGGATTC TGACTGAGCG TTCACAGAGG 
AAGGCGTTCC TGCAGGCCCG GAGCTGCATT GAGGACCGAC TGAGGCTGGA GGATGAGAAC 
GAGAAGCAGG AGCGGCTCCT CATGAGCCTC CTGCCCCGGA ACGTTGCCAT GGAGATGAAG 
GAGGACTTCC TGAAGCCCCC TGAGAGGATT TTCCACAAGA TTTACATCCA GAGGCACGAC 
AATGTGAGCA TCCTGTTTGC TGACATCGTG GGTTTCACGG GCTTGGCATC CCAGTGCACA 
GCCCAGGAGC TGGTGAAACT CCTCAATGAG CTCTTCGGCA AGTTCGATGA ATTAGCCACG 
GAGAACCACT GTCGCCGCAT CAAGATTCTC GGGGACTGCT ACTACTGCGT GTCGGGCCTC 
ACCCAGCCCA AGACTGACCA TGCCCACTGC TGTGTGGAGA TGGGACTCGA CATGATTGAT 
ACCATCACAT CTGTGGCTGA AGCCACCGAG GTGGATCTGA ACATGCGTGT GGGTCTGCAC 
ACGGGCAGGG TCCTCTGTGG TGTCCTGGGC TTGCGCAAGT GGCAGTACGA CGTGTGGTCC 
AATGATGTGA CCTTGGCCAA TGTCATGGAA GCCGCTGGCC TGCCAGGGAA GGTTCATATC 
ACAAAGACGA CCCTAGCGTG CTTGAATGGG GACTACGAGG TAGAACCGGG TTACGGACAT 
GAGAGGAACA GTTTCTTGAA AACTCATAAC ATCGAAACCT TTTTTATTGT GCCATCCCAT 
CGCCGAAAGA TATTTCCAGG CCTGATTCTC TCAGATATAA AACCGGCCAA AAGGATGAAG 
TTCAAGACTG TCTGCTACCT GCTGGTGCAG CTCATGCACT GCCGGAAAAT GTTCAAGGCC 
GAGATCCCCT TCTCCAATGT CATGACCTGC GAGGACGATG ACAAGCGGAG GGCATTAAGA 
ACAGCCTCGG AAAAACTCAG AAACCGCTCA TCTTTTTCTA CCAACGTTGT CTACACCACC 
CCGGGCACTC GCGTCAACAG GTACATCAGC CGCCTCTTAG AAGCCCGCCA GACAGAGCTG 
GAGATGGCAG ACCTGAACTT CTTTACCCTG AAGTACAAAC ATGTCGAACG GGAGCAAAAG 
TACCACCAGC TTCAGGACGA GTATTTCACC AGCGCCGTTG TCCTCACCCT CATCCTGGCT 
GCCTTATTTG GCCTTGTCTA CCTTCTAATA TTCCCACAGA GTGTGGTCGT CCTGCTCCTG 
CTAGTATTCT GCATCTGCTT CCTGGTGGCC TGTGTCCTGT ACCTGCACAT CACCCGGGTC 
CAGTGTTTTC CAGGGTGCCT GACGATTCAG ATTCGCACTG TCCTGTGTAT TTTCATAGTG 
GTCTTAATCT ACTCAGTAGC CCAAGGTTGT GTGGTGGGCT GCCTGCCTTG GGCCTGGAGC 
TCCAAGCCCA ACAGTTCCCT GGTGGTCCTT TCGTCTGGGG GCCAGCGCAC AGCCCTGCCC 
ACCCTGCCCT GCGAGTCTAC ACACCATGCC CTGCTCTGCT GCCTGGTGGG CACCCTCCCG 
CTAGCCATAT TTTTCCGGGT GTCCTCCTTG CCAAAAATGA TCCTGCTCTC CGGGCTCACC 
ACGTCCTACA TCCTCGTTCT GGAGCTCAGC GGATACACCA GGACTGGGGG TGGTGCCGTC 
TCCGGGCGCA GCTACGAGCC GATTGTGGCC ATCCTGCTCT TCTCCTGTGC GCTGGCCCTG 
CATGCCAGGC AGGTGGACAT CAGGCTGAGG CTGGACTACC TCTGGGCCGC ACAGGCAGAG 
GAGGAGCGAG AGGACATGGA GAAGGTGAAG CTGGACAACA GGCGCATCCT CTTCAACCTC 
CTGCCGGCCC ACGTCGCCCA GCACTTCCTC ATGTCCAACC CTCGGAACAT GGACCTCTAC 
TACCAGTCCT ACTCCCAGGT GGGCGTCATG TTTGCCTCCA TCCCCAACTT CAATGACTTC 
TACATCGAGC TGGACGGCAA CAACATGGGG GTGGAGTGTC TGCGGCTTCT CAACGAGATC 
ATCGCCGACT TTGACGAGCT CATGGAAAAA GACTTTTACA AGGACATAGA GAAGATCAAG 
ACCATCGGGA GCACCTACAT GGCCGCTGTG GGGCTAGCGC CCACCTCGGG GACCAAGGCT 
AAGAAGTCCA TCTCCTCCCA CCTGAGCACG CTGGCGGACT TTGCCATTGA GATGTTTGAC 
GTTCTGGATG AAATCAACTA CCAGTCTTAC AACGACTTTG TCCTCCGAGT TGGTGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADCY1 ( XM_005249585.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005249642.1 Homo sapiens adenylate cyclase 1 (ADCY1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu41063
Clone ID Related Accession (Same CDS sequence)	XM_005249585.2
Accession Version	XM_005249585.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1692bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	adenylate cyclase type 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005249585.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGGGG CGCCGCGCGG CGGAGGCGGC GGCGGAGGCG GCGCGGGCGA GCCCGGGGGC 
GCCGAGCGGG CGGCCGGGAC AAGCCGCCGG CGCGGGCTCC GGGCGTGCGA CGAGGAGTTC 
GCTTGCCCAG AGCTGGAGGC GCTGTTCCGC GGCTACACGC TGCGGCTGGA GCAGGCGGCC 
ACGCTGAAGG CGCTGGCCGT TCTCAGCCTG CTGGCGGGCG CGCTGGCGCT GGCCGAGCTG 
CTGGGCGCGC CGGGGCCCGC GCCCGGCCTG GCCAAGGGCT CACACCCGGT GCACTGCGTC 
CTCTTCCTGG CGCTGCTCGT GGTAACCAAC GTCCGGTCCC TGCAGGTGCC CCAGCTGCAG 
CAGGTCGGCC AGCTGGCGCT GCTCTTCAGC CTCACCTTCG CGCTGCTCTG CTGTCCTTTC 
GCGCTGGGCG GCCCCGCCCG GGGTTCCGCC GGGGCCGCTG GGGGGCCAGC GACCGCCGAA 
CAAGGGGTTT GGCAGCTCCT TTTGGTCACC TTCGTGTCCT ATGCCTTGCT GCCCGTGCGC 
AGCCTGCTGG CCATAGGCTT TGGGCTCGTG GTGGCTGCGT CGCACTTGCT GGTCACAGCC 
ACCTTGGTCC CCGCCAAGCG CCCACGTCTC TGGAGGACGC TCGGTGCCAA TGCCTTGCTC 
TTCGTCGGTG TGAACATGTA TGGGGTCTTT GTGCGGATTC TGACTGAGCG TTCACAGAGG 
AAGGCGTTCC TGCAGGCCCG GAGCTGCATT GAGGACCGAC TGAGGCTGGA GGATGAGAAC 
GAGAAGCAGG AGCGGCTCCT CATGAGCCTC CTGCCCCGGA ACGTTGCCAT GGAGATGAAG 
GAGGACTTCC TGAAGCCCCC TGAGAGGATT TTCCACAAGA TTTACATCCA GAGGCACGAC 
AATGTGAGCA TCCTGTTTGC TGACATCGTG GGTTTCACGG GCTTGGCATC CCAGTGCACA 
GCCCAGGAGC TGGTGAAACT CCTCAATGAG CTCTTCGGCA AGTTCGATGA ATTAGCCACG 
GAGAACCACT GTCGCCGCAT CAAGATTCTC GGGGACTGCT ACTACTGCGT GTCGGGCCTC 
ACCCAGCCCA AGACTGACCA TGCCCACTGC TGTGTGGAGA TGGGACTCGA CATGATTGAT 
ACCATCACAT CTGTGGCTGA AGCCACCGAG GTGGATCTGA ACATGCGTGT GGGTCTGCAC 
ACGGGCAGGG TCCTCTGTGG TGTCCTGGGC TTGCGCAAGT GGCAGTACGA CGTGTGGTCC 
AATGATGTGA CCTTGGCCAA TGTCATGGAA GCCGCTGGCC TGCCAGGGAA GGTTCATATC 
ACAAAGACGA CCCTAGCGTG CTTGAATGGG GACTACGAGG TAGAACCGGG TTACGGACAT 
GAGAGGAACA GTTTCTTGAA AACTCATAAC ATCGAAACCT TTTTTATTGT GCCATCCCAT 
CGCCGAAAGA TATTTCCAGG CCTGATTCTC TCAGATATAA AACCGGCCAA AAGGATGAAG 
TTCAAGACTG TCTGCTACCT GCTGGTGCAG CTCATGCACT GCCGGAAAAT GTTCAAGGCC 
GAGATCCCCT TCTCCAATGT CATGACCTGC GAGGACGATG ACAAGGTTCA GATCCATCCC 
TCACTGAGTG GCCTGGATGT CCTCCTGGGG TTTTGGTCTC CCACCCTGCA ACGGGGACGA 
CTGTGCACGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005249642.1
CDS	17..1708
Translation	MAGAPRGGGGGGGGAGEPGGAERAAGTSRRRGLRACDEEFACPELEALFRGYTLRLEQAATLKALAVLSLLAGALALAELLGAPGPAPGLAKGSHPVHCVLFLALLVVTNVRSLQVPQLQQVGQLALLFSLTFALLCCPFALGGPARGSAGAAGGPATAEQGVWQLLLVTFVSYALLPVRSLLAIGFGLVVAASHLLVTATLVPAKRPRLWRTLGANALLFVGVNMYGVFVRILTERSQRKAFLQARSCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGYGHERNSFLKTHNIETFFIVPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKVQIHPSLSGLDVLLGFWSPTLQRGRLCT

Target ORF information:

RefSeq Version	XM_005249585.2
Organism	Homo sapiens(human)
Definition	Homo sapiens adenylate cyclase 1 (ADCY1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005249585.2

ORF Insert Sequence:

ATGGCGGGGG CGCCGCGCGG CGGAGGCGGC GGCGGAGGCG GCGCGGGCGA GCCCGGGGGC 
GCCGAGCGGG CGGCCGGGAC AAGCCGCCGG CGCGGGCTCC GGGCGTGCGA CGAGGAGTTC 
GCTTGCCCAG AGCTGGAGGC GCTGTTCCGC GGCTACACGC TGCGGCTGGA GCAGGCGGCC 
ACGCTGAAGG CGCTGGCCGT TCTCAGCCTG CTGGCGGGCG CGCTGGCGCT GGCCGAGCTG 
CTGGGCGCGC CGGGGCCCGC GCCCGGCCTG GCCAAGGGCT CACACCCGGT GCACTGCGTC 
CTCTTCCTGG CGCTGCTCGT GGTAACCAAC GTCCGGTCCC TGCAGGTGCC CCAGCTGCAG 
CAGGTCGGCC AGCTGGCGCT GCTCTTCAGC CTCACCTTCG CGCTGCTCTG CTGTCCTTTC 
GCGCTGGGCG GCCCCGCCCG GGGTTCCGCC GGGGCCGCTG GGGGGCCAGC GACCGCCGAA 
CAAGGGGTTT GGCAGCTCCT TTTGGTCACC TTCGTGTCCT ATGCCTTGCT GCCCGTGCGC 
AGCCTGCTGG CCATAGGCTT TGGGCTCGTG GTGGCTGCGT CGCACTTGCT GGTCACAGCC 
ACCTTGGTCC CCGCCAAGCG CCCACGTCTC TGGAGGACGC TCGGTGCCAA TGCCTTGCTC 
TTCGTCGGTG TGAACATGTA TGGGGTCTTT GTGCGGATTC TGACTGAGCG TTCACAGAGG 
AAGGCGTTCC TGCAGGCCCG GAGCTGCATT GAGGACCGAC TGAGGCTGGA GGATGAGAAC 
GAGAAGCAGG AGCGGCTCCT CATGAGCCTC CTGCCCCGGA ACGTTGCCAT GGAGATGAAG 
GAGGACTTCC TGAAGCCCCC TGAGAGGATT TTCCACAAGA TTTACATCCA GAGGCACGAC 
AATGTGAGCA TCCTGTTTGC TGACATCGTG GGTTTCACGG GCTTGGCATC CCAGTGCACA 
GCCCAGGAGC TGGTGAAACT CCTCAATGAG CTCTTCGGCA AGTTCGATGA ATTAGCCACG 
GAGAACCACT GTCGCCGCAT CAAGATTCTC GGGGACTGCT ACTACTGCGT GTCGGGCCTC 
ACCCAGCCCA AGACTGACCA TGCCCACTGC TGTGTGGAGA TGGGACTCGA CATGATTGAT 
ACCATCACAT CTGTGGCTGA AGCCACCGAG GTGGATCTGA ACATGCGTGT GGGTCTGCAC 
ACGGGCAGGG TCCTCTGTGG TGTCCTGGGC TTGCGCAAGT GGCAGTACGA CGTGTGGTCC 
AATGATGTGA CCTTGGCCAA TGTCATGGAA GCCGCTGGCC TGCCAGGGAA GGTTCATATC 
ACAAAGACGA CCCTAGCGTG CTTGAATGGG GACTACGAGG TAGAACCGGG TTACGGACAT 
GAGAGGAACA GTTTCTTGAA AACTCATAAC ATCGAAACCT TTTTTATTGT GCCATCCCAT 
CGCCGAAAGA TATTTCCAGG CCTGATTCTC TCAGATATAA AACCGGCCAA AAGGATGAAG 
TTCAAGACTG TCTGCTACCT GCTGGTGCAG CTCATGCACT GCCGGAAAAT GTTCAAGGCC 
GAGATCCCCT TCTCCAATGT CATGACCTGC GAGGACGATG ACAAGGTTCA GATCCATCCC 
TCACTGAGTG GCCTGGATGT CCTCCTGGGG TTTTGGTCTC CCACCCTGCA ACGGGGACGA 
CTGTGCACGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Protein kinase A inhibition facilitates the antitumor activity of xanthohumol, a valosin-containing protein inhibitor.
Cancer science108(4)785-794(2017 Apr)
Shikata Y,Yoshimaru T,Komatsu M,Katoh H,Sato R,Kanagaki S,Okazaki Y,Toyokuni S,Tashiro E,Ishikawa S,Katagiri T,Imoto M

Identification of a selective small-molecule inhibitor of type 1 adenylyl cyclase activity with analgesic properties.
Science signaling10(467)(2017 Feb)
Brust TF,Alongkronrusmee D,Soto-Velasquez M,Baldwin TA,Ye Z,Dai M,Dessauer CW,van Rijn RM,Watts VJ

STC1 interference on calcitonin family of receptors signaling during osteoblastogenesis via adenylate cyclase inhibition.
Molecular and cellular endocrinology40378-87(2015 Mar)
Terra SR,Cardoso JC,F?lix RC,Martins LA,Souza DO,Guma FC,Can?rio AV,Schein V

Membranous adenylyl cyclase 1 activation is regulated by oxidation of N- and C-terminal methionine residues in calmodulin.
Biochemical pharmacology93(2)196-209(2015 Jan)
L?bker C,Urbauer RJ,Moskovitz J,Dove S,Weisemann J,Fedorova M,Urbauer JL,Seifert R

Overexpression of the type 1 adenylyl cyclase in the forebrain leads to deficits of behavioral inhibition.
The Journal of neuroscience : the official journal of the Society for Neuroscience35(1)339-51(2015 Jan)
Chen X,Cao H,Saraf A,Zweifel LS,Storm DR

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ADCY1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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