Gene Symbol | CORIN |
Entrez Gene ID | 10699 |
Full Name | corin, serine peptidase |
Synonyms | ATC2,CRN,Lrp4,PEE5,TMPRSS10 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. The encoded protein converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013]. |
Disorder MIM: | |
Disorder Html: | Preeclampsia/eclampsia 5, 614595 (3) |