CES1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CES1
Entrez Gene ID	1066
Full Name	carboxylesterase 1
Synonyms	ACAT,CE-1,CEH,CES2,HMSE,HMSE1,PCE-1,REH,SES1,TGH,hCE-1
General protein information	Preferred Names carboxylesterase 1 Names liver carboxylesterase 1 acyl coenzyme A:cholesterol acyltransferase brain carboxylesterase hBr1 carboxylesterase 1 (monocyte/macrophage serine esterase 1) carboxylesterase 2 (liver) cholesteryl ester hydrolase cocaine carboxylesterase egasyn human monocyte/macrophage serine esterase 1 methylumbelliferyl-acetate deacetylase 1 monocyte/macrophage serine esterase retinyl ester hydrolase serine esterase 1 triacylglycerol hydrolase
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 16 Map Location: 16q12.2
Summary	This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Jun 2010].
Disorder MIM:	114835
Disorder Html:	Carboxylesterase 1 deficiency (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_005255774.1	XP_005255831.1	liver carboxylesterase 1 isoform X1
NM_001266.4	NP_001257.4	liver carboxylesterase 1 isoform c precursor
NM_001266.5	NP_001257.4	liver carboxylesterase 1 isoform c precursor
NM_001025195.2	NP_001020366.1	liver carboxylesterase 1 isoform a precursor
NM_001025194.1	NP_001020365.1	liver carboxylesterase 1 isoform b precursor
XM_005255774.2	XP_005255831.1	liver carboxylesterase 1 isoform X1
NM_001025195.1	NP_001020366.1	liver carboxylesterase 1 isoform a precursor
NM_001025194.2	NP_001020365.1	liver carboxylesterase 1 isoform b precursor

Pathways from BioSystems

Homologies

	CES2	XP_001095823.2
Bos taurus (cattle)	BREH1	NP_001012287.1
Gallus gallus (chicken)	LOC769339	XP_004949956.1
Danio rerio (zebrafish)	ces2	NP_001070720.1
Xenopus tropicalis (tropical clawed frog)	ces5a	NP_001265277.1
Xenopus tropicalis (tropical clawed frog)	LOC100493652	XP_004913615.1
Bos taurus (cattle)	CES1	NP_001069022.1
Xenopus tropicalis (tropical clawed frog)	ces2	NP_001072187.1
Bos taurus (cattle)	LOC508916	NP_001039483.1
Danio rerio (zebrafish)	si:ch211-93f2.1	XP_001921966.4
Homo sapiens (human)	CES1	NP_001257.4
Canis lupus familiaris (dog)	CES1	NP_001003085.1
Mus musculus (house mouse)	Ces1d	NP_444430.2
Rattus norvegicus (Norway rat)	Ces1d	NP_579829.3
Gallus gallus (chicken)	CES1	XP_001231970.2
Xenopus tropicalis (tropical clawed frog)	LOC100493819	XP_002935836.2
Xenopus tropicalis (tropical clawed frog)	ces3	NP_001120019.1
Danio rerio (zebrafish)	ces3	NP_001038401.1
Xenopus tropicalis (tropical clawed frog)	LOC100494149	XP_002943465.2
Xenopus tropicalis (tropical clawed frog)	LOC100493994	XP_004913616.1

Gene Ontology
Bibliography

Related articles in PubMed

Silencing Carboxylesterase 1 in Human THP-1 Macrophages Perturbs Genes Regulated by PPARg/RXR and RAR/RXR: Downregulation of CYP27A1-LXR? Signaling.
Mangum LC, Hou X, Borazjani A, Lee JH, Ross MK, Crow JA
The Biochemical journal(2018 Jan)

Effects of Genetic Variants on Carboxylesterase 1 Gene Expression, and Clopidogrel Pharmacokinetics and Antiplatelet Effects.
Neuvonen M, Tarkiainen EK, Tornio A, Hirvensalo P, Tapaninen T, Paile-Hyv?rinen M, Itkonen MK, Holmberg MT, K?rj? V, M?nnist? VT, Neuvonen PJ, Pihlajam?ki J, Backman JT, Niemi M
Basic & clinical pharmacology & toxicology(2017 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

An association was identified with a genetic variation in CES1 and early-onset capecitabine-related toxicity.
Title: Novel Genetic Variants in Carboxylesterase 1 Predict Severe Early-Onset Capecitabine-Related Toxicity.

Reduced CES1 expression/activity could promote development of METH-PAH.
Title: Reduced carboxylesterase 1 is associated with endothelial injury in methamphetamine-induced pulmonary arterial hypertension.

The intestinal transport of oseltamivir, a hCE1 substrate, could be evaluated in subclone #78 cell monolayers.
Title: Establishment and Characterization of a Novel Caco-2 Subclone with a Similar Low Expression Level of Human Carboxylesterase 1 to Human Small Intestine.

These data suggest that CES1 genetic variants and gender are important contributing factors to variability in dabigatran etexilate activation in humans.
Title: Dabigatran etexilate activation is affected by the CES1 genetic polymorphism G143E (rs71647871) and gender.

Our study identified CYP2C19*3 and CES1 rs8192950 as genetic polymorphisms related to recurrent ischemic events in patients with extracranial or intracranial occlusive disease, demonstrating the important roles of CYP2C19 and CES1 in patients treated with clopidogrel
Title: Impact of genetic polymorphisms related to clopidogrel or acetylsalicylic acid pharmacology on clinical outcome in Chinese patients with symptomatic extracranial or intracranial stenosis.

The following CES1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CES1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu13480	NM_001266.5 Latest version!	Homo sapiens carboxylesterase 1 (CES1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu13494	NM_001025194.2 Latest version!	Homo sapiens carboxylesterase 1 (CES1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu18153	NM_001025195.2 Latest version!	Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu49244	XM_005255774.2 Latest version!	Homo sapiens carboxylesterase 1 (CES1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
View Old Accession Versions >>
OHu13480	NM_001266.4	Homo sapiens carboxylesterase 1 (CES1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu49244	XM_005255774.1	Homo sapiens carboxylesterase 1 (CES1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu18153	NM_001025195.1	Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
OHu13494	NM_001025194.1	Homo sapiens carboxylesterase 1 (CES1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CES1 ( NM_001266.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001257.4 Homo sapiens carboxylesterase 1 (CES1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu13480
Clone ID Related Accession (Same CDS sequence)	NM_001266.4 , NM_001266.5
Accession Version	NM_001266.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1701bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Homo sapiens(human)
Product	liver carboxylesterase 1 isoform c precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AU139632.1, L07765.1 and BC012418.1. On or before Mar 4, 2006 this sequence version replaced XM_945034.1, XM_941222.1, NM_001266.3. Transcript Variant: This variant (3) uses a different in-frame splice site at the end of two separate exons compared to variant 1. The resulting isoform (c) has the same N- and C-termini but is shorter by 2 aa compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC012418.1, AK290623.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTGGCTCC GTGCCTTTAT CCTGGCCACT CTCTCTGCTT CCGCGGCTTG GGGGCATCCG 
TCCTCGCCAC CTGTGGTGGA CACCGTGCAT GGCAAAGTGC TGGGGAAGTT CGTCAGCTTA 
GAAGGATTTG CACAGCCTGT GGCCATTTTC CTGGGAATCC CTTTTGCCAA GCCGCCTCTT 
GGACCCCTGA GGTTTACTCC ACCGCAGCCT GCAGAACCAT GGAGCTTTGT GAAGAATGCC 
ACCTCGTACC CTCCTATGTG CACCCAAGAT CCCAAGGCGG GGCAGTTACT CTCAGAGCTA 
TTTACAAACC GAAAGGAGAA CATTCCTCTC AAGCTTTCTG AAGACTGTCT TTACCTCAAT 
ATTTACACTC CTGCTGACTT GACCAAGAAA AACAGGCTGC CGGTGATGGT GTGGATCCAC 
GGAGGGGGGC TGATGGTGGG TGCGGCATCA ACCTATGATG GGCTGGCCCT TGCTGCCCAT 
GAAAACGTGG TGGTGGTGAC CATTCAATAT CGCCTGGGCA TCTGGGGATT CTTCAGCACA 
GGGGATGAAC ACAGCCGGGG GAACTGGGGT CACCTGGACC AGGTGGCTGC CCTGCGCTGG 
GTCCAGGACA ACATTGCCAG CTTTGGAGGG AACCCAGGCT CTGTGACCAT CTTTGGAGAG 
TCAGCGGGAG GAGAAAGTGT CTCTGTTCTT GTTTTGTCTC CATTGGCCAA GAACCTCTTC 
CACCGGGCCA TTTCTGAGAG TGGCGTGGCC CTCACTTCTG TTCTGGTGAA GAAAGGTGAT 
GTCAAGCCCT TGGCTGAGCA AATTGCTATC ACTGCTGGGT GCAAAACCAC CACCTCTGCT 
GTCATGGTTC ACTGCCTGCG ACAGAAGACG GAAGAGGAGC TCTTGGAGAC GACATTGAAA 
ATGAAATTCT TATCTCTGGA CTTACAGGGA GACCCCAGAG AGAGTCAACC CCTTCTGGGC 
ACTGTGATTG ATGGGATGCT GCTGCTGAAA ACACCTGAAG AGCTTCAAGC TGAAAGGAAT 
TTCCACACTG TCCCCTACAT GGTCGGAATT AACAAGCAGG AGTTTGGCTG GTTGATTCCA 
ATGTTGATGA GCTATCCACT CTCCGAAGGG CAACTGGACC AGAAGACAGC CATGTCACTC 
CTGTGGAAGT CCTATCCCCT TGTTTGCATT GCTAAGGAAC TGATTCCAGA AGCCACTGAG 
AAATACTTAG GAGGAACAGA CGACACTGTC AAAAAGAAAG ACCTGTTCCT GGACTTGATA 
GCAGATGTGA TGTTTGGTGT CCCATCTGTG ATTGTGGCCC GGAACCACAG AGATGCTGGA 
GCACCCACCT ACATGTATGA GTTTCAGTAC CGTCCAAGCT TCTCATCAGA CATGAAACCC 
AAGACGGTGA TAGGAGACCA CGGGGATGAG CTCTTCTCCG TCTTTGGGGC CCCATTTTTA 
AAAGAGGGTG CCTCAGAAGA GGAGATCAGA CTTAGCAAGA TGGTGATGAA ATTCTGGGCC 
AACTTTGCTC GCAATGGAAA CCCCAATGGG GAAGGGCTGC CCCACTGGCC AGAGTACAAC 
CAGAAGGAAG GGTATCTGCA GATTGGTGCC AACACCCAGG CGGCCCAGAA GCTGAAGGAC 
AAAGAAGTAG CTTTCTGGAC CAACCTCTTT GCCAAGAAGG CAGTGGAGAA GCCACCCCAG 
ACAGAACACA TAGAGCTGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001257.4
CDS	109..1809
Translation	MWLRAFILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEVAFWTNLFAKKAVEKPPQTEHIEL

Target ORF information:

RefSeq Version	NM_001266.4
Organism	Homo sapiens(human)
Definition	Homo sapiens carboxylesterase 1 (CES1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001266.4

ORF Insert Sequence:

ATGTGGCTCC GTGCCTTTAT CCTGGCCACT CTCTCTGCTT CCGCGGCTTG GGGGCATCCG 
TCCTCGCCAC CTGTGGTGGA CACCGTGCAT GGCAAAGTGC TGGGGAAGTT CGTCAGCTTA 
GAAGGATTTG CACAGCCTGT GGCCATTTTC CTGGGAATCC CTTTTGCCAA GCCGCCTCTT 
GGACCCCTGA GGTTTACTCC ACCGCAGCCT GCAGAACCAT GGAGCTTTGT GAAGAATGCC 
ACCTCGTACC CTCCTATGTG CACCCAAGAT CCCAAGGCGG GGCAGTTACT CTCAGAGCTA 
TTTACAAACC GAAAGGAGAA CATTCCTCTC AAGCTTTCTG AAGACTGTCT TTACCTCAAT 
ATTTACACTC CTGCTGACTT GACCAAGAAA AACAGGCTGC CGGTGATGGT GTGGATCCAC 
GGAGGGGGGC TGATGGTGGG TGCGGCATCA ACCTATGATG GGCTGGCCCT TGCTGCCCAT 
GAAAACGTGG TGGTGGTGAC CATTCAATAT CGCCTGGGCA TCTGGGGATT CTTCAGCACA 
GGGGATGAAC ACAGCCGGGG GAACTGGGGT CACCTGGACC AGGTGGCTGC CCTGCGCTGG 
GTCCAGGACA ACATTGCCAG CTTTGGAGGG AACCCAGGCT CTGTGACCAT CTTTGGAGAG 
TCAGCGGGAG GAGAAAGTGT CTCTGTTCTT GTTTTGTCTC CATTGGCCAA GAACCTCTTC 
CACCGGGCCA TTTCTGAGAG TGGCGTGGCC CTCACTTCTG TTCTGGTGAA GAAAGGTGAT 
GTCAAGCCCT TGGCTGAGCA AATTGCTATC ACTGCTGGGT GCAAAACCAC CACCTCTGCT 
GTCATGGTTC ACTGCCTGCG ACAGAAGACG GAAGAGGAGC TCTTGGAGAC GACATTGAAA 
ATGAAATTCT TATCTCTGGA CTTACAGGGA GACCCCAGAG AGAGTCAACC CCTTCTGGGC 
ACTGTGATTG ATGGGATGCT GCTGCTGAAA ACACCTGAAG AGCTTCAAGC TGAAAGGAAT 
TTCCACACTG TCCCCTACAT GGTCGGAATT AACAAGCAGG AGTTTGGCTG GTTGATTCCA 
ATGTTGATGA GCTATCCACT CTCCGAAGGG CAACTGGACC AGAAGACAGC CATGTCACTC 
CTGTGGAAGT CCTATCCCCT TGTTTGCATT GCTAAGGAAC TGATTCCAGA AGCCACTGAG 
AAATACTTAG GAGGAACAGA CGACACTGTC AAAAAGAAAG ACCTGTTCCT GGACTTGATA 
GCAGATGTGA TGTTTGGTGT CCCATCTGTG ATTGTGGCCC GGAACCACAG AGATGCTGGA 
GCACCCACCT ACATGTATGA GTTTCAGTAC CGTCCAAGCT TCTCATCAGA CATGAAACCC 
AAGACGGTGA TAGGAGACCA CGGGGATGAG CTCTTCTCCG TCTTTGGGGC CCCATTTTTA 
AAAGAGGGTG CCTCAGAAGA GGAGATCAGA CTTAGCAAGA TGGTGATGAA ATTCTGGGCC 
AACTTTGCTC GCAATGGAAA CCCCAATGGG GAAGGGCTGC CCCACTGGCC AGAGTACAAC 
CAGAAGGAAG GGTATCTGCA GATTGGTGCC AACACCCAGG CGGCCCAGAA GCTGAAGGAC 
AAAGAAGTAG CTTTCTGGAC CAACCTCTTT GCCAAGAAGG CAGTGGAGAA GCCACCCCAG 
ACAGAACACA TAGAGCTGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CES1 ( NM_001266.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_001257.4 Homo sapiens carboxylesterase 1 (CES1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu13480
Clone ID Related Accession (Same CDS sequence)	NM_001266.4 , NM_001266.5
Accession Version	NM_001266.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1701bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	liver carboxylesterase 1 isoform c precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AU139632.1, L07765.1 and BC012418.1. On Jun 2, 2019 this sequence version replaced NM_001266.4. Transcript Variant: This variant (3) uses a different in-frame splice site at the end of two separate exons compared to variant 1. The resulting isoform (c) has the same N- and C-termini but is shorter by 2 aa compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC012418.1, AK290623.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTGGCTCC GTGCCTTTAT CCTGGCCACT CTCTCTGCTT CCGCGGCTTG GGGGCATCCG 
TCCTCGCCAC CTGTGGTGGA CACCGTGCAT GGCAAAGTGC TGGGGAAGTT CGTCAGCTTA 
GAAGGATTTG CACAGCCTGT GGCCATTTTC CTGGGAATCC CTTTTGCCAA GCCGCCTCTT 
GGACCCCTGA GGTTTACTCC ACCGCAGCCT GCAGAACCAT GGAGCTTTGT GAAGAATGCC 
ACCTCGTACC CTCCTATGTG CACCCAAGAT CCCAAGGCGG GGCAGTTACT CTCAGAGCTA 
TTTACAAACC GAAAGGAGAA CATTCCTCTC AAGCTTTCTG AAGACTGTCT TTACCTCAAT 
ATTTACACTC CTGCTGACTT GACCAAGAAA AACAGGCTGC CGGTGATGGT GTGGATCCAC 
GGAGGGGGGC TGATGGTGGG TGCGGCATCA ACCTATGATG GGCTGGCCCT TGCTGCCCAT 
GAAAACGTGG TGGTGGTGAC CATTCAATAT CGCCTGGGCA TCTGGGGATT CTTCAGCACA 
GGGGATGAAC ACAGCCGGGG GAACTGGGGT CACCTGGACC AGGTGGCTGC CCTGCGCTGG 
GTCCAGGACA ACATTGCCAG CTTTGGAGGG AACCCAGGCT CTGTGACCAT CTTTGGAGAG 
TCAGCGGGAG GAGAAAGTGT CTCTGTTCTT GTTTTGTCTC CATTGGCCAA GAACCTCTTC 
CACCGGGCCA TTTCTGAGAG TGGCGTGGCC CTCACTTCTG TTCTGGTGAA GAAAGGTGAT 
GTCAAGCCCT TGGCTGAGCA AATTGCTATC ACTGCTGGGT GCAAAACCAC CACCTCTGCT 
GTCATGGTTC ACTGCCTGCG ACAGAAGACG GAAGAGGAGC TCTTGGAGAC GACATTGAAA 
ATGAAATTCT TATCTCTGGA CTTACAGGGA GACCCCAGAG AGAGTCAACC CCTTCTGGGC 
ACTGTGATTG ATGGGATGCT GCTGCTGAAA ACACCTGAAG AGCTTCAAGC TGAAAGGAAT 
TTCCACACTG TCCCCTACAT GGTCGGAATT AACAAGCAGG AGTTTGGCTG GTTGATTCCA 
ATGTTGATGA GCTATCCACT CTCCGAAGGG CAACTGGACC AGAAGACAGC CATGTCACTC 
CTGTGGAAGT CCTATCCCCT TGTTTGCATT GCTAAGGAAC TGATTCCAGA AGCCACTGAG 
AAATACTTAG GAGGAACAGA CGACACTGTC AAAAAGAAAG ACCTGTTCCT GGACTTGATA 
GCAGATGTGA TGTTTGGTGT CCCATCTGTG ATTGTGGCCC GGAACCACAG AGATGCTGGA 
GCACCCACCT ACATGTATGA GTTTCAGTAC CGTCCAAGCT TCTCATCAGA CATGAAACCC 
AAGACGGTGA TAGGAGACCA CGGGGATGAG CTCTTCTCCG TCTTTGGGGC CCCATTTTTA 
AAAGAGGGTG CCTCAGAAGA GGAGATCAGA CTTAGCAAGA TGGTGATGAA ATTCTGGGCC 
AACTTTGCTC GCAATGGAAA CCCCAATGGG GAAGGGCTGC CCCACTGGCC AGAGTACAAC 
CAGAAGGAAG GGTATCTGCA GATTGGTGCC AACACCCAGG CGGCCCAGAA GCTGAAGGAC 
AAAGAAGTAG CTTTCTGGAC CAACCTCTTT GCCAAGAAGG CAGTGGAGAA GCCACCCCAG 
ACAGAACACA TAGAGCTGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001257.4
CDS	42..1742
Translation	MWLRAFILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEVAFWTNLFAKKAVEKPPQTEHIEL

Target ORF information:

RefSeq Version	NM_001266.5
Organism	Homo sapiens(human)
Definition	Homo sapiens carboxylesterase 1 (CES1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001266.5

ORF Insert Sequence:

ATGTGGCTCC GTGCCTTTAT CCTGGCCACT CTCTCTGCTT CCGCGGCTTG GGGGCATCCG 
TCCTCGCCAC CTGTGGTGGA CACCGTGCAT GGCAAAGTGC TGGGGAAGTT CGTCAGCTTA 
GAAGGATTTG CACAGCCTGT GGCCATTTTC CTGGGAATCC CTTTTGCCAA GCCGCCTCTT 
GGACCCCTGA GGTTTACTCC ACCGCAGCCT GCAGAACCAT GGAGCTTTGT GAAGAATGCC 
ACCTCGTACC CTCCTATGTG CACCCAAGAT CCCAAGGCGG GGCAGTTACT CTCAGAGCTA 
TTTACAAACC GAAAGGAGAA CATTCCTCTC AAGCTTTCTG AAGACTGTCT TTACCTCAAT 
ATTTACACTC CTGCTGACTT GACCAAGAAA AACAGGCTGC CGGTGATGGT GTGGATCCAC 
GGAGGGGGGC TGATGGTGGG TGCGGCATCA ACCTATGATG GGCTGGCCCT TGCTGCCCAT 
GAAAACGTGG TGGTGGTGAC CATTCAATAT CGCCTGGGCA TCTGGGGATT CTTCAGCACA 
GGGGATGAAC ACAGCCGGGG GAACTGGGGT CACCTGGACC AGGTGGCTGC CCTGCGCTGG 
GTCCAGGACA ACATTGCCAG CTTTGGAGGG AACCCAGGCT CTGTGACCAT CTTTGGAGAG 
TCAGCGGGAG GAGAAAGTGT CTCTGTTCTT GTTTTGTCTC CATTGGCCAA GAACCTCTTC 
CACCGGGCCA TTTCTGAGAG TGGCGTGGCC CTCACTTCTG TTCTGGTGAA GAAAGGTGAT 
GTCAAGCCCT TGGCTGAGCA AATTGCTATC ACTGCTGGGT GCAAAACCAC CACCTCTGCT 
GTCATGGTTC ACTGCCTGCG ACAGAAGACG GAAGAGGAGC TCTTGGAGAC GACATTGAAA 
ATGAAATTCT TATCTCTGGA CTTACAGGGA GACCCCAGAG AGAGTCAACC CCTTCTGGGC 
ACTGTGATTG ATGGGATGCT GCTGCTGAAA ACACCTGAAG AGCTTCAAGC TGAAAGGAAT 
TTCCACACTG TCCCCTACAT GGTCGGAATT AACAAGCAGG AGTTTGGCTG GTTGATTCCA 
ATGTTGATGA GCTATCCACT CTCCGAAGGG CAACTGGACC AGAAGACAGC CATGTCACTC 
CTGTGGAAGT CCTATCCCCT TGTTTGCATT GCTAAGGAAC TGATTCCAGA AGCCACTGAG 
AAATACTTAG GAGGAACAGA CGACACTGTC AAAAAGAAAG ACCTGTTCCT GGACTTGATA 
GCAGATGTGA TGTTTGGTGT CCCATCTGTG ATTGTGGCCC GGAACCACAG AGATGCTGGA 
GCACCCACCT ACATGTATGA GTTTCAGTAC CGTCCAAGCT TCTCATCAGA CATGAAACCC 
AAGACGGTGA TAGGAGACCA CGGGGATGAG CTCTTCTCCG TCTTTGGGGC CCCATTTTTA 
AAAGAGGGTG CCTCAGAAGA GGAGATCAGA CTTAGCAAGA TGGTGATGAA ATTCTGGGCC 
AACTTTGCTC GCAATGGAAA CCCCAATGGG GAAGGGCTGC CCCACTGGCC AGAGTACAAC 
CAGAAGGAAG GGTATCTGCA GATTGGTGCC AACACCCAGG CGGCCCAGAA GCTGAAGGAC 
AAAGAAGTAG CTTTCTGGAC CAACCTCTTT GCCAAGAAGG CAGTGGAGAA GCCACCCCAG 
ACAGAACACA TAGAGCTGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CES1 ( NM_001025194.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001020365.1 Homo sapiens carboxylesterase 1 (CES1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu13494
Clone ID Related Accession (Same CDS sequence)	NM_001025194.1 , NM_001025194.2
Accession Version	NM_001025194.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1704bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Homo sapiens(human)
Product	liver carboxylesterase 1 isoform b precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AU139632.1, AB119995.1 and BC012418.1. On Sep 20, 2006 this sequence version replaced XM_001130190.1. Transcript Variant: This variant (2) uses a different in-frame splice site at the end of a coding exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter by 1 aa compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC110338.1, AB119995.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTGGCTCC GTGCCTTTAT CCTGGCCACT CTCTCTGCTT CCGCGGCTTG GGGGCATCCG 
TCCTCGCCAC CTGTGGTGGA CACCGTGCAT GGCAAAGTGC TGGGGAAGTT CGTCAGCTTA 
GAAGGATTTG CACAGCCTGT GGCCATTTTC CTGGGAATCC CTTTTGCCAA GCCGCCTCTT 
GGACCCCTGA GGTTTACTCC ACCGCAGCCT GCAGAACCAT GGAGCTTTGT GAAGAATGCC 
ACCTCGTACC CTCCTATGTG CACCCAAGAT CCCAAGGCGG GGCAGTTACT CTCAGAGCTA 
TTTACAAACC GAAAGGAGAA CATTCCTCTC AAGCTTTCTG AAGACTGTCT TTACCTCAAT 
ATTTACACTC CTGCTGACTT GACCAAGAAA AACAGGCTGC CGGTGATGGT GTGGATCCAC 
GGAGGGGGGC TGATGGTGGG TGCGGCATCA ACCTATGATG GGCTGGCCCT TGCTGCCCAT 
GAAAACGTGG TGGTGGTGAC CATTCAATAT CGCCTGGGCA TCTGGGGATT CTTCAGCACA 
GGGGATGAAC ACAGCCGGGG GAACTGGGGT CACCTGGACC AGGTGGCTGC CCTGCGCTGG 
GTCCAGGACA ACATTGCCAG CTTTGGAGGG AACCCAGGCT CTGTGACCAT CTTTGGAGAG 
TCAGCGGGAG GAGAAAGTGT CTCTGTTCTT GTTTTGTCTC CATTGGCCAA GAACCTCTTC 
CACCGGGCCA TTTCTGAGAG TGGCGTGGCC CTCACTTCTG TTCTGGTGAA GAAAGGTGAT 
GTCAAGCCCT TGGCTGAGCA AATTGCTATC ACTGCTGGGT GCAAAACCAC CACCTCTGCT 
GTCATGGTTC ACTGCCTGCG ACAGAAGACG GAAGAGGAGC TCTTGGAGAC GACATTGAAA 
ATGAAATTCT TATCTCTGGA CTTACAGGGA GACCCCAGAG AGAGTCAACC CCTTCTGGGC 
ACTGTGATTG ATGGGATGCT GCTGCTGAAA ACACCTGAAG AGCTTCAAGC TGAAAGGAAT 
TTCCACACTG TCCCCTACAT GGTCGGAATT AACAAGCAGG AGTTTGGCTG GTTGATTCCA 
ATGCAGTTGA TGAGCTATCC ACTCTCCGAA GGGCAACTGG ACCAGAAGAC AGCCATGTCA 
CTCCTGTGGA AGTCCTATCC CCTTGTTTGC ATTGCTAAGG AACTGATTCC AGAAGCCACT 
GAGAAATACT TAGGAGGAAC AGACGACACT GTCAAAAAGA AAGACCTGTT CCTGGACTTG 
ATAGCAGATG TGATGTTTGG TGTCCCATCT GTGATTGTGG CCCGGAACCA CAGAGATGCT 
GGAGCACCCA CCTACATGTA TGAGTTTCAG TACCGTCCAA GCTTCTCATC AGACATGAAA 
CCCAAGACGG TGATAGGAGA CCACGGGGAT GAGCTCTTCT CCGTCTTTGG GGCCCCATTT 
TTAAAAGAGG GTGCCTCAGA AGAGGAGATC AGACTTAGCA AGATGGTGAT GAAATTCTGG 
GCCAACTTTG CTCGCAATGG AAACCCCAAT GGGGAAGGGC TGCCCCACTG GCCAGAGTAC 
AACCAGAAGG AAGGGTATCT GCAGATTGGT GCCAACACCC AGGCGGCCCA GAAGCTGAAG 
GACAAAGAAG TAGCTTTCTG GACCAACCTC TTTGCCAAGA AGGCAGTGGA GAAGCCACCC 
CAGACAGAAC ACATAGAGCT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001020365.1
CDS	109..1812
Translation	MWLRAFILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEVAFWTNLFAKKAVEKPPQTEHIEL

Target ORF information:

RefSeq Version	NM_001025194.1
Organism	Homo sapiens(human)
Definition	Homo sapiens carboxylesterase 1 (CES1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001025194.1

ORF Insert Sequence:

ATGTGGCTCC GTGCCTTTAT CCTGGCCACT CTCTCTGCTT CCGCGGCTTG GGGGCATCCG 
TCCTCGCCAC CTGTGGTGGA CACCGTGCAT GGCAAAGTGC TGGGGAAGTT CGTCAGCTTA 
GAAGGATTTG CACAGCCTGT GGCCATTTTC CTGGGAATCC CTTTTGCCAA GCCGCCTCTT 
GGACCCCTGA GGTTTACTCC ACCGCAGCCT GCAGAACCAT GGAGCTTTGT GAAGAATGCC 
ACCTCGTACC CTCCTATGTG CACCCAAGAT CCCAAGGCGG GGCAGTTACT CTCAGAGCTA 
TTTACAAACC GAAAGGAGAA CATTCCTCTC AAGCTTTCTG AAGACTGTCT TTACCTCAAT 
ATTTACACTC CTGCTGACTT GACCAAGAAA AACAGGCTGC CGGTGATGGT GTGGATCCAC 
GGAGGGGGGC TGATGGTGGG TGCGGCATCA ACCTATGATG GGCTGGCCCT TGCTGCCCAT 
GAAAACGTGG TGGTGGTGAC CATTCAATAT CGCCTGGGCA TCTGGGGATT CTTCAGCACA 
GGGGATGAAC ACAGCCGGGG GAACTGGGGT CACCTGGACC AGGTGGCTGC CCTGCGCTGG 
GTCCAGGACA ACATTGCCAG CTTTGGAGGG AACCCAGGCT CTGTGACCAT CTTTGGAGAG 
TCAGCGGGAG GAGAAAGTGT CTCTGTTCTT GTTTTGTCTC CATTGGCCAA GAACCTCTTC 
CACCGGGCCA TTTCTGAGAG TGGCGTGGCC CTCACTTCTG TTCTGGTGAA GAAAGGTGAT 
GTCAAGCCCT TGGCTGAGCA AATTGCTATC ACTGCTGGGT GCAAAACCAC CACCTCTGCT 
GTCATGGTTC ACTGCCTGCG ACAGAAGACG GAAGAGGAGC TCTTGGAGAC GACATTGAAA 
ATGAAATTCT TATCTCTGGA CTTACAGGGA GACCCCAGAG AGAGTCAACC CCTTCTGGGC 
ACTGTGATTG ATGGGATGCT GCTGCTGAAA ACACCTGAAG AGCTTCAAGC TGAAAGGAAT 
TTCCACACTG TCCCCTACAT GGTCGGAATT AACAAGCAGG AGTTTGGCTG GTTGATTCCA 
ATGCAGTTGA TGAGCTATCC ACTCTCCGAA GGGCAACTGG ACCAGAAGAC AGCCATGTCA 
CTCCTGTGGA AGTCCTATCC CCTTGTTTGC ATTGCTAAGG AACTGATTCC AGAAGCCACT 
GAGAAATACT TAGGAGGAAC AGACGACACT GTCAAAAAGA AAGACCTGTT CCTGGACTTG 
ATAGCAGATG TGATGTTTGG TGTCCCATCT GTGATTGTGG CCCGGAACCA CAGAGATGCT 
GGAGCACCCA CCTACATGTA TGAGTTTCAG TACCGTCCAA GCTTCTCATC AGACATGAAA 
CCCAAGACGG TGATAGGAGA CCACGGGGAT GAGCTCTTCT CCGTCTTTGG GGCCCCATTT 
TTAAAAGAGG GTGCCTCAGA AGAGGAGATC AGACTTAGCA AGATGGTGAT GAAATTCTGG 
GCCAACTTTG CTCGCAATGG AAACCCCAAT GGGGAAGGGC TGCCCCACTG GCCAGAGTAC 
AACCAGAAGG AAGGGTATCT GCAGATTGGT GCCAACACCC AGGCGGCCCA GAAGCTGAAG 
GACAAAGAAG TAGCTTTCTG GACCAACCTC TTTGCCAAGA AGGCAGTGGA GAAGCCACCC 
CAGACAGAAC ACATAGAGCT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CES1 ( NM_001025194.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001020365.1 Homo sapiens carboxylesterase 1 (CES1), transcript variant 2, mRNA.

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CloneID	OHu13494
Clone ID Related Accession (Same CDS sequence)	NM_001025194.1 , NM_001025194.2
Accession Version	NM_001025194.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1704bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-25
Organism	Homo sapiens(human)
Product	liver carboxylesterase 1 isoform b precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AU139632.1, AB119995.1 and BC012418.1. On Jun 2, 2019 this sequence version replaced NM_001025194.1. Transcript Variant: This variant (2) uses a different in-frame splice site at the end of a coding exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter by 1 aa compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189664.131430.1, BC110338.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTGGCTCC GTGCCTTTAT CCTGGCCACT CTCTCTGCTT CCGCGGCTTG GGGGCATCCG 
TCCTCGCCAC CTGTGGTGGA CACCGTGCAT GGCAAAGTGC TGGGGAAGTT CGTCAGCTTA 
GAAGGATTTG CACAGCCTGT GGCCATTTTC CTGGGAATCC CTTTTGCCAA GCCGCCTCTT 
GGACCCCTGA GGTTTACTCC ACCGCAGCCT GCAGAACCAT GGAGCTTTGT GAAGAATGCC 
ACCTCGTACC CTCCTATGTG CACCCAAGAT CCCAAGGCGG GGCAGTTACT CTCAGAGCTA 
TTTACAAACC GAAAGGAGAA CATTCCTCTC AAGCTTTCTG AAGACTGTCT TTACCTCAAT 
ATTTACACTC CTGCTGACTT GACCAAGAAA AACAGGCTGC CGGTGATGGT GTGGATCCAC 
GGAGGGGGGC TGATGGTGGG TGCGGCATCA ACCTATGATG GGCTGGCCCT TGCTGCCCAT 
GAAAACGTGG TGGTGGTGAC CATTCAATAT CGCCTGGGCA TCTGGGGATT CTTCAGCACA 
GGGGATGAAC ACAGCCGGGG GAACTGGGGT CACCTGGACC AGGTGGCTGC CCTGCGCTGG 
GTCCAGGACA ACATTGCCAG CTTTGGAGGG AACCCAGGCT CTGTGACCAT CTTTGGAGAG 
TCAGCGGGAG GAGAAAGTGT CTCTGTTCTT GTTTTGTCTC CATTGGCCAA GAACCTCTTC 
CACCGGGCCA TTTCTGAGAG TGGCGTGGCC CTCACTTCTG TTCTGGTGAA GAAAGGTGAT 
GTCAAGCCCT TGGCTGAGCA AATTGCTATC ACTGCTGGGT GCAAAACCAC CACCTCTGCT 
GTCATGGTTC ACTGCCTGCG ACAGAAGACG GAAGAGGAGC TCTTGGAGAC GACATTGAAA 
ATGAAATTCT TATCTCTGGA CTTACAGGGA GACCCCAGAG AGAGTCAACC CCTTCTGGGC 
ACTGTGATTG ATGGGATGCT GCTGCTGAAA ACACCTGAAG AGCTTCAAGC TGAAAGGAAT 
TTCCACACTG TCCCCTACAT GGTCGGAATT AACAAGCAGG AGTTTGGCTG GTTGATTCCA 
ATGCAGTTGA TGAGCTATCC ACTCTCCGAA GGGCAACTGG ACCAGAAGAC AGCCATGTCA 
CTCCTGTGGA AGTCCTATCC CCTTGTTTGC ATTGCTAAGG AACTGATTCC AGAAGCCACT 
GAGAAATACT TAGGAGGAAC AGACGACACT GTCAAAAAGA AAGACCTGTT CCTGGACTTG 
ATAGCAGATG TGATGTTTGG TGTCCCATCT GTGATTGTGG CCCGGAACCA CAGAGATGCT 
GGAGCACCCA CCTACATGTA TGAGTTTCAG TACCGTCCAA GCTTCTCATC AGACATGAAA 
CCCAAGACGG TGATAGGAGA CCACGGGGAT GAGCTCTTCT CCGTCTTTGG GGCCCCATTT 
TTAAAAGAGG GTGCCTCAGA AGAGGAGATC AGACTTAGCA AGATGGTGAT GAAATTCTGG 
GCCAACTTTG CTCGCAATGG AAACCCCAAT GGGGAAGGGC TGCCCCACTG GCCAGAGTAC 
AACCAGAAGG AAGGGTATCT GCAGATTGGT GCCAACACCC AGGCGGCCCA GAAGCTGAAG 
GACAAAGAAG TAGCTTTCTG GACCAACCTC TTTGCCAAGA AGGCAGTGGA GAAGCCACCC 
CAGACAGAAC ACATAGAGCT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001020365.1
CDS	42..1745
Translation	MWLRAFILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEVAFWTNLFAKKAVEKPPQTEHIEL

Target ORF information:

RefSeq Version	NM_001025194.2
Organism	Homo sapiens(human)
Definition	Homo sapiens carboxylesterase 1 (CES1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001025194.2

ORF Insert Sequence:

ATGTGGCTCC GTGCCTTTAT CCTGGCCACT CTCTCTGCTT CCGCGGCTTG GGGGCATCCG 
TCCTCGCCAC CTGTGGTGGA CACCGTGCAT GGCAAAGTGC TGGGGAAGTT CGTCAGCTTA 
GAAGGATTTG CACAGCCTGT GGCCATTTTC CTGGGAATCC CTTTTGCCAA GCCGCCTCTT 
GGACCCCTGA GGTTTACTCC ACCGCAGCCT GCAGAACCAT GGAGCTTTGT GAAGAATGCC 
ACCTCGTACC CTCCTATGTG CACCCAAGAT CCCAAGGCGG GGCAGTTACT CTCAGAGCTA 
TTTACAAACC GAAAGGAGAA CATTCCTCTC AAGCTTTCTG AAGACTGTCT TTACCTCAAT 
ATTTACACTC CTGCTGACTT GACCAAGAAA AACAGGCTGC CGGTGATGGT GTGGATCCAC 
GGAGGGGGGC TGATGGTGGG TGCGGCATCA ACCTATGATG GGCTGGCCCT TGCTGCCCAT 
GAAAACGTGG TGGTGGTGAC CATTCAATAT CGCCTGGGCA TCTGGGGATT CTTCAGCACA 
GGGGATGAAC ACAGCCGGGG GAACTGGGGT CACCTGGACC AGGTGGCTGC CCTGCGCTGG 
GTCCAGGACA ACATTGCCAG CTTTGGAGGG AACCCAGGCT CTGTGACCAT CTTTGGAGAG 
TCAGCGGGAG GAGAAAGTGT CTCTGTTCTT GTTTTGTCTC CATTGGCCAA GAACCTCTTC 
CACCGGGCCA TTTCTGAGAG TGGCGTGGCC CTCACTTCTG TTCTGGTGAA GAAAGGTGAT 
GTCAAGCCCT TGGCTGAGCA AATTGCTATC ACTGCTGGGT GCAAAACCAC CACCTCTGCT 
GTCATGGTTC ACTGCCTGCG ACAGAAGACG GAAGAGGAGC TCTTGGAGAC GACATTGAAA 
ATGAAATTCT TATCTCTGGA CTTACAGGGA GACCCCAGAG AGAGTCAACC CCTTCTGGGC 
ACTGTGATTG ATGGGATGCT GCTGCTGAAA ACACCTGAAG AGCTTCAAGC TGAAAGGAAT 
TTCCACACTG TCCCCTACAT GGTCGGAATT AACAAGCAGG AGTTTGGCTG GTTGATTCCA 
ATGCAGTTGA TGAGCTATCC ACTCTCCGAA GGGCAACTGG ACCAGAAGAC AGCCATGTCA 
CTCCTGTGGA AGTCCTATCC CCTTGTTTGC ATTGCTAAGG AACTGATTCC AGAAGCCACT 
GAGAAATACT TAGGAGGAAC AGACGACACT GTCAAAAAGA AAGACCTGTT CCTGGACTTG 
ATAGCAGATG TGATGTTTGG TGTCCCATCT GTGATTGTGG CCCGGAACCA CAGAGATGCT 
GGAGCACCCA CCTACATGTA TGAGTTTCAG TACCGTCCAA GCTTCTCATC AGACATGAAA 
CCCAAGACGG TGATAGGAGA CCACGGGGAT GAGCTCTTCT CCGTCTTTGG GGCCCCATTT 
TTAAAAGAGG GTGCCTCAGA AGAGGAGATC AGACTTAGCA AGATGGTGAT GAAATTCTGG 
GCCAACTTTG CTCGCAATGG AAACCCCAAT GGGGAAGGGC TGCCCCACTG GCCAGAGTAC 
AACCAGAAGG AAGGGTATCT GCAGATTGGT GCCAACACCC AGGCGGCCCA GAAGCTGAAG 
GACAAAGAAG TAGCTTTCTG GACCAACCTC TTTGCCAAGA AGGCAGTGGA GAAGCCACCC 
CAGACAGAAC ACATAGAGCT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CES1 ( NM_001025195.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001020366.1 Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu18153
Clone ID Related Accession (Same CDS sequence)	NM_001025195.2 , NM_001025195.1
Accession Version	NM_001025195.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1707bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-25
Organism	Homo sapiens(human)
Product	liver carboxylesterase 1 isoform a precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AU139632.1, CB137639.1, L07764.1 and BC012418.1. This sequence is a reference standard in the RefSeqGene project. On Jun 2, 2019 this sequence version replaced NM_001025195.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DRR138522.1513432.1, SRR5189664.146968.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTGGCTCC GTGCCTTTAT CCTGGCCACT CTCTCTGCTT CCGCGGCTTG GGCAGGGCAT 
CCGTCCTCGC CACCTGTGGT GGACACCGTG CATGGCAAAG TGCTGGGGAA GTTCGTCAGC 
TTAGAAGGAT TTGCACAGCC TGTGGCCATT TTCCTGGGAA TCCCTTTTGC CAAGCCGCCT 
CTTGGACCCC TGAGGTTTAC TCCACCGCAG CCTGCAGAAC CATGGAGCTT TGTGAAGAAT 
GCCACCTCGT ACCCTCCTAT GTGCACCCAA GATCCCAAGG CGGGGCAGTT ACTCTCAGAG 
CTATTTACAA ACCGAAAGGA GAACATTCCT CTCAAGCTTT CTGAAGACTG TCTTTACCTC 
AATATTTACA CTCCTGCTGA CTTGACCAAG AAAAACAGGC TGCCGGTGAT GGTGTGGATC 
CACGGAGGGG GGCTGATGGT GGGTGCGGCA TCAACCTATG ATGGGCTGGC CCTTGCTGCC 
CATGAAAACG TGGTGGTGGT GACCATTCAA TATCGCCTGG GCATCTGGGG ATTCTTCAGC 
ACAGGGGATG AACACAGCCG GGGGAACTGG GGTCACCTGG ACCAGGTGGC TGCCCTGCGC 
TGGGTCCAGG ACAACATTGC CAGCTTTGGA GGGAACCCAG GCTCTGTGAC CATCTTTGGA 
GAGTCAGCGG GAGGAGAAAG TGTCTCTGTT CTTGTTTTGT CTCCATTGGC CAAGAACCTC 
TTCCACCGGG CCATTTCTGA GAGTGGCGTG GCCCTCACTT CTGTTCTGGT GAAGAAAGGT 
GATGTCAAGC CCTTGGCTGA GCAAATTGCT ATCACTGCTG GGTGCAAAAC CACCACCTCT 
GCTGTCATGG TTCACTGCCT GCGACAGAAG ACGGAAGAGG AGCTCTTGGA GACGACATTG 
AAAATGAAAT TCTTATCTCT GGACTTACAG GGAGACCCCA GAGAGAGTCA ACCCCTTCTG 
GGCACTGTGA TTGATGGGAT GCTGCTGCTG AAAACACCTG AAGAGCTTCA AGCTGAAAGG 
AATTTCCACA CTGTCCCCTA CATGGTCGGA ATTAACAAGC AGGAGTTTGG CTGGTTGATT 
CCAATGCAGT TGATGAGCTA TCCACTCTCC GAAGGGCAAC TGGACCAGAA GACAGCCATG 
TCACTCCTGT GGAAGTCCTA TCCCCTTGTT TGCATTGCTA AGGAACTGAT TCCAGAAGCC 
ACTGAGAAAT ACTTAGGAGG AACAGACGAC ACTGTCAAAA AGAAAGACCT GTTCCTGGAC 
TTGATAGCAG ATGTGATGTT TGGTGTCCCA TCTGTGATTG TGGCCCGGAA CCACAGAGAT 
GCTGGAGCAC CCACCTACAT GTATGAGTTT CAGTACCGTC CAAGCTTCTC ATCAGACATG 
AAACCCAAGA CGGTGATAGG AGACCACGGG GATGAGCTCT TCTCCGTCTT TGGGGCCCCA 
TTTTTAAAAG AGGGTGCCTC AGAAGAGGAG ATCAGACTTA GCAAGATGGT GATGAAATTC 
TGGGCCAACT TTGCTCGCAA TGGAAACCCC AATGGGGAAG GGCTGCCCCA CTGGCCAGAG 
TACAACCAGA AGGAAGGGTA TCTGCAGATT GGTGCCAACA CCCAGGCGGC CCAGAAGCTG 
AAGGACAAAG AAGTAGCTTT CTGGACCAAC CTCTTTGCCA AGAAGGCAGT GGAGAAGCCA 
CCCCAGACAG AACACATAGA GCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001020366.1
CDS	42..1748
Translation	MWLRAFILATLSASAAWAGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEVAFWTNLFAKKAVEKPPQTEHIEL

Target ORF information:

RefSeq Version	NM_001025195.2
Organism	Homo sapiens(human)
Definition	Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001025195.2

ORF Insert Sequence:

ATGTGGCTCC GTGCCTTTAT CCTGGCCACT CTCTCTGCTT CCGCGGCTTG GGCAGGGCAT 
CCGTCCTCGC CACCTGTGGT GGACACCGTG CATGGCAAAG TGCTGGGGAA GTTCGTCAGC 
TTAGAAGGAT TTGCACAGCC TGTGGCCATT TTCCTGGGAA TCCCTTTTGC CAAGCCGCCT 
CTTGGACCCC TGAGGTTTAC TCCACCGCAG CCTGCAGAAC CATGGAGCTT TGTGAAGAAT 
GCCACCTCGT ACCCTCCTAT GTGCACCCAA GATCCCAAGG CGGGGCAGTT ACTCTCAGAG 
CTATTTACAA ACCGAAAGGA GAACATTCCT CTCAAGCTTT CTGAAGACTG TCTTTACCTC 
AATATTTACA CTCCTGCTGA CTTGACCAAG AAAAACAGGC TGCCGGTGAT GGTGTGGATC 
CACGGAGGGG GGCTGATGGT GGGTGCGGCA TCAACCTATG ATGGGCTGGC CCTTGCTGCC 
CATGAAAACG TGGTGGTGGT GACCATTCAA TATCGCCTGG GCATCTGGGG ATTCTTCAGC 
ACAGGGGATG AACACAGCCG GGGGAACTGG GGTCACCTGG ACCAGGTGGC TGCCCTGCGC 
TGGGTCCAGG ACAACATTGC CAGCTTTGGA GGGAACCCAG GCTCTGTGAC CATCTTTGGA 
GAGTCAGCGG GAGGAGAAAG TGTCTCTGTT CTTGTTTTGT CTCCATTGGC CAAGAACCTC 
TTCCACCGGG CCATTTCTGA GAGTGGCGTG GCCCTCACTT CTGTTCTGGT GAAGAAAGGT 
GATGTCAAGC CCTTGGCTGA GCAAATTGCT ATCACTGCTG GGTGCAAAAC CACCACCTCT 
GCTGTCATGG TTCACTGCCT GCGACAGAAG ACGGAAGAGG AGCTCTTGGA GACGACATTG 
AAAATGAAAT TCTTATCTCT GGACTTACAG GGAGACCCCA GAGAGAGTCA ACCCCTTCTG 
GGCACTGTGA TTGATGGGAT GCTGCTGCTG AAAACACCTG AAGAGCTTCA AGCTGAAAGG 
AATTTCCACA CTGTCCCCTA CATGGTCGGA ATTAACAAGC AGGAGTTTGG CTGGTTGATT 
CCAATGCAGT TGATGAGCTA TCCACTCTCC GAAGGGCAAC TGGACCAGAA GACAGCCATG 
TCACTCCTGT GGAAGTCCTA TCCCCTTGTT TGCATTGCTA AGGAACTGAT TCCAGAAGCC 
ACTGAGAAAT ACTTAGGAGG AACAGACGAC ACTGTCAAAA AGAAAGACCT GTTCCTGGAC 
TTGATAGCAG ATGTGATGTT TGGTGTCCCA TCTGTGATTG TGGCCCGGAA CCACAGAGAT 
GCTGGAGCAC CCACCTACAT GTATGAGTTT CAGTACCGTC CAAGCTTCTC ATCAGACATG 
AAACCCAAGA CGGTGATAGG AGACCACGGG GATGAGCTCT TCTCCGTCTT TGGGGCCCCA 
TTTTTAAAAG AGGGTGCCTC AGAAGAGGAG ATCAGACTTA GCAAGATGGT GATGAAATTC 
TGGGCCAACT TTGCTCGCAA TGGAAACCCC AATGGGGAAG GGCTGCCCCA CTGGCCAGAG 
TACAACCAGA AGGAAGGGTA TCTGCAGATT GGTGCCAACA CCCAGGCGGC CCAGAAGCTG 
AAGGACAAAG AAGTAGCTTT CTGGACCAAC CTCTTTGCCA AGAAGGCAGT GGAGAAGCCA 
CCCCAGACAG AACACATAGA GCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CES1 ( NM_001025195.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001020366.1 Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.

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CloneID	OHu18153
Clone ID Related Accession (Same CDS sequence)	NM_001025195.2 , NM_001025195.1
Accession Version	NM_001025195.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1707bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Homo sapiens(human)
Product	liver carboxylesterase 1 isoform a precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AU139632.1, CB137639.1, L07764.1 and BC012418.1. This sequence is a reference standard in the RefSeqGene project. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK292209.1, SRR1660805.166838.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTGGCTCC GTGCCTTTAT CCTGGCCACT CTCTCTGCTT CCGCGGCTTG GGCAGGGCAT 
CCGTCCTCGC CACCTGTGGT GGACACCGTG CATGGCAAAG TGCTGGGGAA GTTCGTCAGC 
TTAGAAGGAT TTGCACAGCC TGTGGCCATT TTCCTGGGAA TCCCTTTTGC CAAGCCGCCT 
CTTGGACCCC TGAGGTTTAC TCCACCGCAG CCTGCAGAAC CATGGAGCTT TGTGAAGAAT 
GCCACCTCGT ACCCTCCTAT GTGCACCCAA GATCCCAAGG CGGGGCAGTT ACTCTCAGAG 
CTATTTACAA ACCGAAAGGA GAACATTCCT CTCAAGCTTT CTGAAGACTG TCTTTACCTC 
AATATTTACA CTCCTGCTGA CTTGACCAAG AAAAACAGGC TGCCGGTGAT GGTGTGGATC 
CACGGAGGGG GGCTGATGGT GGGTGCGGCA TCAACCTATG ATGGGCTGGC CCTTGCTGCC 
CATGAAAACG TGGTGGTGGT GACCATTCAA TATCGCCTGG GCATCTGGGG ATTCTTCAGC 
ACAGGGGATG AACACAGCCG GGGGAACTGG GGTCACCTGG ACCAGGTGGC TGCCCTGCGC 
TGGGTCCAGG ACAACATTGC CAGCTTTGGA GGGAACCCAG GCTCTGTGAC CATCTTTGGA 
GAGTCAGCGG GAGGAGAAAG TGTCTCTGTT CTTGTTTTGT CTCCATTGGC CAAGAACCTC 
TTCCACCGGG CCATTTCTGA GAGTGGCGTG GCCCTCACTT CTGTTCTGGT GAAGAAAGGT 
GATGTCAAGC CCTTGGCTGA GCAAATTGCT ATCACTGCTG GGTGCAAAAC CACCACCTCT 
GCTGTCATGG TTCACTGCCT GCGACAGAAG ACGGAAGAGG AGCTCTTGGA GACGACATTG 
AAAATGAAAT TCTTATCTCT GGACTTACAG GGAGACCCCA GAGAGAGTCA ACCCCTTCTG 
GGCACTGTGA TTGATGGGAT GCTGCTGCTG AAAACACCTG AAGAGCTTCA AGCTGAAAGG 
AATTTCCACA CTGTCCCCTA CATGGTCGGA ATTAACAAGC AGGAGTTTGG CTGGTTGATT 
CCAATGCAGT TGATGAGCTA TCCACTCTCC GAAGGGCAAC TGGACCAGAA GACAGCCATG 
TCACTCCTGT GGAAGTCCTA TCCCCTTGTT TGCATTGCTA AGGAACTGAT TCCAGAAGCC 
ACTGAGAAAT ACTTAGGAGG AACAGACGAC ACTGTCAAAA AGAAAGACCT GTTCCTGGAC 
TTGATAGCAG ATGTGATGTT TGGTGTCCCA TCTGTGATTG TGGCCCGGAA CCACAGAGAT 
GCTGGAGCAC CCACCTACAT GTATGAGTTT CAGTACCGTC CAAGCTTCTC ATCAGACATG 
AAACCCAAGA CGGTGATAGG AGACCACGGG GATGAGCTCT TCTCCGTCTT TGGGGCCCCA 
TTTTTAAAAG AGGGTGCCTC AGAAGAGGAG ATCAGACTTA GCAAGATGGT GATGAAATTC 
TGGGCCAACT TTGCTCGCAA TGGAAACCCC AATGGGGAAG GGCTGCCCCA CTGGCCAGAG 
TACAACCAGA AGGAAGGGTA TCTGCAGATT GGTGCCAACA CCCAGGCGGC CCAGAAGCTG 
AAGGACAAAG AAGTAGCTTT CTGGACCAAC CTCTTTGCCA AGAAGGCAGT GGAGAAGCCA 
CCCCAGACAG AACACATAGA GCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001020366.1
CDS	109..1815
Translation	MWLRAFILATLSASAAWAGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEVAFWTNLFAKKAVEKPPQTEHIEL

Target ORF information:

RefSeq Version	NM_001025195.1
Organism	Homo sapiens(human)
Definition	Homo sapiens carboxylesterase 1 (CES1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001025195.1

ORF Insert Sequence:

ATGTGGCTCC GTGCCTTTAT CCTGGCCACT CTCTCTGCTT CCGCGGCTTG GGCAGGGCAT 
CCGTCCTCGC CACCTGTGGT GGACACCGTG CATGGCAAAG TGCTGGGGAA GTTCGTCAGC 
TTAGAAGGAT TTGCACAGCC TGTGGCCATT TTCCTGGGAA TCCCTTTTGC CAAGCCGCCT 
CTTGGACCCC TGAGGTTTAC TCCACCGCAG CCTGCAGAAC CATGGAGCTT TGTGAAGAAT 
GCCACCTCGT ACCCTCCTAT GTGCACCCAA GATCCCAAGG CGGGGCAGTT ACTCTCAGAG 
CTATTTACAA ACCGAAAGGA GAACATTCCT CTCAAGCTTT CTGAAGACTG TCTTTACCTC 
AATATTTACA CTCCTGCTGA CTTGACCAAG AAAAACAGGC TGCCGGTGAT GGTGTGGATC 
CACGGAGGGG GGCTGATGGT GGGTGCGGCA TCAACCTATG ATGGGCTGGC CCTTGCTGCC 
CATGAAAACG TGGTGGTGGT GACCATTCAA TATCGCCTGG GCATCTGGGG ATTCTTCAGC 
ACAGGGGATG AACACAGCCG GGGGAACTGG GGTCACCTGG ACCAGGTGGC TGCCCTGCGC 
TGGGTCCAGG ACAACATTGC CAGCTTTGGA GGGAACCCAG GCTCTGTGAC CATCTTTGGA 
GAGTCAGCGG GAGGAGAAAG TGTCTCTGTT CTTGTTTTGT CTCCATTGGC CAAGAACCTC 
TTCCACCGGG CCATTTCTGA GAGTGGCGTG GCCCTCACTT CTGTTCTGGT GAAGAAAGGT 
GATGTCAAGC CCTTGGCTGA GCAAATTGCT ATCACTGCTG GGTGCAAAAC CACCACCTCT 
GCTGTCATGG TTCACTGCCT GCGACAGAAG ACGGAAGAGG AGCTCTTGGA GACGACATTG 
AAAATGAAAT TCTTATCTCT GGACTTACAG GGAGACCCCA GAGAGAGTCA ACCCCTTCTG 
GGCACTGTGA TTGATGGGAT GCTGCTGCTG AAAACACCTG AAGAGCTTCA AGCTGAAAGG 
AATTTCCACA CTGTCCCCTA CATGGTCGGA ATTAACAAGC AGGAGTTTGG CTGGTTGATT 
CCAATGCAGT TGATGAGCTA TCCACTCTCC GAAGGGCAAC TGGACCAGAA GACAGCCATG 
TCACTCCTGT GGAAGTCCTA TCCCCTTGTT TGCATTGCTA AGGAACTGAT TCCAGAAGCC 
ACTGAGAAAT ACTTAGGAGG AACAGACGAC ACTGTCAAAA AGAAAGACCT GTTCCTGGAC 
TTGATAGCAG ATGTGATGTT TGGTGTCCCA TCTGTGATTG TGGCCCGGAA CCACAGAGAT 
GCTGGAGCAC CCACCTACAT GTATGAGTTT CAGTACCGTC CAAGCTTCTC ATCAGACATG 
AAACCCAAGA CGGTGATAGG AGACCACGGG GATGAGCTCT TCTCCGTCTT TGGGGCCCCA 
TTTTTAAAAG AGGGTGCCTC AGAAGAGGAG ATCAGACTTA GCAAGATGGT GATGAAATTC 
TGGGCCAACT TTGCTCGCAA TGGAAACCCC AATGGGGAAG GGCTGCCCCA CTGGCCAGAG 
TACAACCAGA AGGAAGGGTA TCTGCAGATT GGTGCCAACA CCCAGGCGGC CCAGAAGCTG 
AAGGACAAAG AAGTAGCTTT CTGGACCAAC CTCTTTGCCA AGAAGGCAGT GGAGAAGCCA 
CCCCAGACAG AACACATAGA GCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CES1 ( XM_005255774.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_005255831.1 Homo sapiens carboxylesterase 1 (CES1), transcript variant X1, mRNA.

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CloneID	OHu49244
Clone ID Related Accession (Same CDS sequence)	XM_005255774.1 , XM_005255774.2
Accession Version	XM_005255774.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1704bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	liver carboxylesterase 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGGCTCC GTGCCTTTAT CCTGGCCACT CTCTCTGCTT CCGCGGCTTG GGCAGGGCAT 
CCGTCCTCGC CACCTGTGGT GGACACCGTG CATGGCAAAG TGCTGGGGAA GTTCGTCAGC 
TTAGAAGGAT TTGCACAGCC TGTGGCCATT TTCCTGGGAA TCCCTTTTGC CAAGCCGCCT 
CTTGGACCCC TGAGGTTTAC TCCACCGCAG CCTGCAGAAC CATGGAGCTT TGTGAAGAAT 
GCCACCTCGT ACCCTCCTAT GTGCACCCAA GATCCCAAGG CGGGGCAGTT ACTCTCAGAG 
CTATTTACAA ACCGAAAGGA GAACATTCCT CTCAAGCTTT CTGAAGACTG TCTTTACCTC 
AATATTTACA CTCCTGCTGA CTTGACCAAG AAAAACAGGC TGCCGGTGAT GGTGTGGATC 
CACGGAGGGG GGCTGATGGT GGGTGCGGCA TCAACCTATG ATGGGCTGGC CCTTGCTGCC 
CATGAAAACG TGGTGGTGGT GACCATTCAA TATCGCCTGG GCATCTGGGG ATTCTTCAGC 
ACAGGGGATG AACACAGCCG GGGGAACTGG GGTCACCTGG ACCAGGTGGC TGCCCTGCGC 
TGGGTCCAGG ACAACATTGC CAGCTTTGGA GGGAACCCAG GCTCTGTGAC CATCTTTGGA 
GAGTCAGCGG GAGGAGAAAG TGTCTCTGTT CTTGTTTTGT CTCCATTGGC CAAGAACCTC 
TTCCACCGGG CCATTTCTGA GAGTGGCGTG GCCCTCACTT CTGTTCTGGT GAAGAAAGGT 
GATGTCAAGC CCTTGGCTGA GCAAATTGCT ATCACTGCTG GGTGCAAAAC CACCACCTCT 
GCTGTCATGG TTCACTGCCT GCGACAGAAG ACGGAAGAGG AGCTCTTGGA GACGACATTG 
AAAATGAAAT TCTTATCTCT GGACTTACAG GGAGACCCCA GAGAGAGTCA ACCCCTTCTG 
GGCACTGTGA TTGATGGGAT GCTGCTGCTG AAAACACCTG AAGAGCTTCA AGCTGAAAGG 
AATTTCCACA CTGTCCCCTA CATGGTCGGA ATTAACAAGC AGGAGTTTGG CTGGTTGATT 
CCAATGTTGA TGAGCTATCC ACTCTCCGAA GGGCAACTGG ACCAGAAGAC AGCCATGTCA 
CTCCTGTGGA AGTCCTATCC CCTTGTTTGC ATTGCTAAGG AACTGATTCC AGAAGCCACT 
GAGAAATACT TAGGAGGAAC AGACGACACT GTCAAAAAGA AAGACCTGTT CCTGGACTTG 
ATAGCAGATG TGATGTTTGG TGTCCCATCT GTGATTGTGG CCCGGAACCA CAGAGATGCT 
GGAGCACCCA CCTACATGTA TGAGTTTCAG TACCGTCCAA GCTTCTCATC AGACATGAAA 
CCCAAGACGG TGATAGGAGA CCACGGGGAT GAGCTCTTCT CCGTCTTTGG GGCCCCATTT 
TTAAAAGAGG GTGCCTCAGA AGAGGAGATC AGACTTAGCA AGATGGTGAT GAAATTCTGG 
GCCAACTTTG CTCGCAATGG AAACCCCAAT GGGGAAGGGC TGCCCCACTG GCCAGAGTAC 
AACCAGAAGG AAGGGTATCT GCAGATTGGT GCCAACACCC AGGCGGCCCA GAAGCTGAAG 
GACAAAGAAG TAGCTTTCTG GACCAACCTC TTTGCCAAGA AGGCAGTGGA GAAGCCACCC 
CAGACAGAAC ACATAGAGCT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005255831.1
CDS	132..1835
Translation	MWLRAFILATLSASAAWAGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEVAFWTNLFAKKAVEKPPQTEHIEL

Target ORF information:

RefSeq Version	XM_005255774.1
Organism	Homo sapiens(human)
Definition	Homo sapiens carboxylesterase 1 (CES1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005255774.1

ORF Insert Sequence:

ATGTGGCTCC GTGCCTTTAT CCTGGCCACT CTCTCTGCTT CCGCGGCTTG GGCAGGGCAT 
CCGTCCTCGC CACCTGTGGT GGACACCGTG CATGGCAAAG TGCTGGGGAA GTTCGTCAGC 
TTAGAAGGAT TTGCACAGCC TGTGGCCATT TTCCTGGGAA TCCCTTTTGC CAAGCCGCCT 
CTTGGACCCC TGAGGTTTAC TCCACCGCAG CCTGCAGAAC CATGGAGCTT TGTGAAGAAT 
GCCACCTCGT ACCCTCCTAT GTGCACCCAA GATCCCAAGG CGGGGCAGTT ACTCTCAGAG 
CTATTTACAA ACCGAAAGGA GAACATTCCT CTCAAGCTTT CTGAAGACTG TCTTTACCTC 
AATATTTACA CTCCTGCTGA CTTGACCAAG AAAAACAGGC TGCCGGTGAT GGTGTGGATC 
CACGGAGGGG GGCTGATGGT GGGTGCGGCA TCAACCTATG ATGGGCTGGC CCTTGCTGCC 
CATGAAAACG TGGTGGTGGT GACCATTCAA TATCGCCTGG GCATCTGGGG ATTCTTCAGC 
ACAGGGGATG AACACAGCCG GGGGAACTGG GGTCACCTGG ACCAGGTGGC TGCCCTGCGC 
TGGGTCCAGG ACAACATTGC CAGCTTTGGA GGGAACCCAG GCTCTGTGAC CATCTTTGGA 
GAGTCAGCGG GAGGAGAAAG TGTCTCTGTT CTTGTTTTGT CTCCATTGGC CAAGAACCTC 
TTCCACCGGG CCATTTCTGA GAGTGGCGTG GCCCTCACTT CTGTTCTGGT GAAGAAAGGT 
GATGTCAAGC CCTTGGCTGA GCAAATTGCT ATCACTGCTG GGTGCAAAAC CACCACCTCT 
GCTGTCATGG TTCACTGCCT GCGACAGAAG ACGGAAGAGG AGCTCTTGGA GACGACATTG 
AAAATGAAAT TCTTATCTCT GGACTTACAG GGAGACCCCA GAGAGAGTCA ACCCCTTCTG 
GGCACTGTGA TTGATGGGAT GCTGCTGCTG AAAACACCTG AAGAGCTTCA AGCTGAAAGG 
AATTTCCACA CTGTCCCCTA CATGGTCGGA ATTAACAAGC AGGAGTTTGG CTGGTTGATT 
CCAATGTTGA TGAGCTATCC ACTCTCCGAA GGGCAACTGG ACCAGAAGAC AGCCATGTCA 
CTCCTGTGGA AGTCCTATCC CCTTGTTTGC ATTGCTAAGG AACTGATTCC AGAAGCCACT 
GAGAAATACT TAGGAGGAAC AGACGACACT GTCAAAAAGA AAGACCTGTT CCTGGACTTG 
ATAGCAGATG TGATGTTTGG TGTCCCATCT GTGATTGTGG CCCGGAACCA CAGAGATGCT 
GGAGCACCCA CCTACATGTA TGAGTTTCAG TACCGTCCAA GCTTCTCATC AGACATGAAA 
CCCAAGACGG TGATAGGAGA CCACGGGGAT GAGCTCTTCT CCGTCTTTGG GGCCCCATTT 
TTAAAAGAGG GTGCCTCAGA AGAGGAGATC AGACTTAGCA AGATGGTGAT GAAATTCTGG 
GCCAACTTTG CTCGCAATGG AAACCCCAAT GGGGAAGGGC TGCCCCACTG GCCAGAGTAC 
AACCAGAAGG AAGGGTATCT GCAGATTGGT GCCAACACCC AGGCGGCCCA GAAGCTGAAG 
GACAAAGAAG TAGCTTTCTG GACCAACCTC TTTGCCAAGA AGGCAGTGGA GAAGCCACCC 
CAGACAGAAC ACATAGAGCT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CES1 ( XM_005255774.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005255831.1 Homo sapiens carboxylesterase 1 (CES1), transcript variant X1, mRNA.

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CloneID	OHu49244
Clone ID Related Accession (Same CDS sequence)	XM_005255774.1 , XM_005255774.2
Accession Version	XM_005255774.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1704bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	liver carboxylesterase 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005255774.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGGCTCC GTGCCTTTAT CCTGGCCACT CTCTCTGCTT CCGCGGCTTG GGCAGGGCAT 
CCGTCCTCGC CACCTGTGGT GGACACCGTG CATGGCAAAG TGCTGGGGAA GTTCGTCAGC 
TTAGAAGGAT TTGCACAGCC TGTGGCCATT TTCCTGGGAA TCCCTTTTGC CAAGCCGCCT 
CTTGGACCCC TGAGGTTTAC TCCACCGCAG CCTGCAGAAC CATGGAGCTT TGTGAAGAAT 
GCCACCTCGT ACCCTCCTAT GTGCACCCAA GATCCCAAGG CGGGGCAGTT ACTCTCAGAG 
CTATTTACAA ACCGAAAGGA GAACATTCCT CTCAAGCTTT CTGAAGACTG TCTTTACCTC 
AATATTTACA CTCCTGCTGA CTTGACCAAG AAAAACAGGC TGCCGGTGAT GGTGTGGATC 
CACGGAGGGG GGCTGATGGT GGGTGCGGCA TCAACCTATG ATGGGCTGGC CCTTGCTGCC 
CATGAAAACG TGGTGGTGGT GACCATTCAA TATCGCCTGG GCATCTGGGG ATTCTTCAGC 
ACAGGGGATG AACACAGCCG GGGGAACTGG GGTCACCTGG ACCAGGTGGC TGCCCTGCGC 
TGGGTCCAGG ACAACATTGC CAGCTTTGGA GGGAACCCAG GCTCTGTGAC CATCTTTGGA 
GAGTCAGCGG GAGGAGAAAG TGTCTCTGTT CTTGTTTTGT CTCCATTGGC CAAGAACCTC 
TTCCACCGGG CCATTTCTGA GAGTGGCGTG GCCCTCACTT CTGTTCTGGT GAAGAAAGGT 
GATGTCAAGC CCTTGGCTGA GCAAATTGCT ATCACTGCTG GGTGCAAAAC CACCACCTCT 
GCTGTCATGG TTCACTGCCT GCGACAGAAG ACGGAAGAGG AGCTCTTGGA GACGACATTG 
AAAATGAAAT TCTTATCTCT GGACTTACAG GGAGACCCCA GAGAGAGTCA ACCCCTTCTG 
GGCACTGTGA TTGATGGGAT GCTGCTGCTG AAAACACCTG AAGAGCTTCA AGCTGAAAGG 
AATTTCCACA CTGTCCCCTA CATGGTCGGA ATTAACAAGC AGGAGTTTGG CTGGTTGATT 
CCAATGTTGA TGAGCTATCC ACTCTCCGAA GGGCAACTGG ACCAGAAGAC AGCCATGTCA 
CTCCTGTGGA AGTCCTATCC CCTTGTTTGC ATTGCTAAGG AACTGATTCC AGAAGCCACT 
GAGAAATACT TAGGAGGAAC AGACGACACT GTCAAAAAGA AAGACCTGTT CCTGGACTTG 
ATAGCAGATG TGATGTTTGG TGTCCCATCT GTGATTGTGG CCCGGAACCA CAGAGATGCT 
GGAGCACCCA CCTACATGTA TGAGTTTCAG TACCGTCCAA GCTTCTCATC AGACATGAAA 
CCCAAGACGG TGATAGGAGA CCACGGGGAT GAGCTCTTCT CCGTCTTTGG GGCCCCATTT 
TTAAAAGAGG GTGCCTCAGA AGAGGAGATC AGACTTAGCA AGATGGTGAT GAAATTCTGG 
GCCAACTTTG CTCGCAATGG AAACCCCAAT GGGGAAGGGC TGCCCCACTG GCCAGAGTAC 
AACCAGAAGG AAGGGTATCT GCAGATTGGT GCCAACACCC AGGCGGCCCA GAAGCTGAAG 
GACAAAGAAG TAGCTTTCTG GACCAACCTC TTTGCCAAGA AGGCAGTGGA GAAGCCACCC 
CAGACAGAAC ACATAGAGCT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005255831.1
CDS	73..1776
Translation	MWLRAFILATLSASAAWAGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEVAFWTNLFAKKAVEKPPQTEHIEL

Target ORF information:

RefSeq Version	XM_005255774.2
Organism	Homo sapiens(human)
Definition	Homo sapiens carboxylesterase 1 (CES1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005255774.2

ORF Insert Sequence:

ATGTGGCTCC GTGCCTTTAT CCTGGCCACT CTCTCTGCTT CCGCGGCTTG GGCAGGGCAT 
CCGTCCTCGC CACCTGTGGT GGACACCGTG CATGGCAAAG TGCTGGGGAA GTTCGTCAGC 
TTAGAAGGAT TTGCACAGCC TGTGGCCATT TTCCTGGGAA TCCCTTTTGC CAAGCCGCCT 
CTTGGACCCC TGAGGTTTAC TCCACCGCAG CCTGCAGAAC CATGGAGCTT TGTGAAGAAT 
GCCACCTCGT ACCCTCCTAT GTGCACCCAA GATCCCAAGG CGGGGCAGTT ACTCTCAGAG 
CTATTTACAA ACCGAAAGGA GAACATTCCT CTCAAGCTTT CTGAAGACTG TCTTTACCTC 
AATATTTACA CTCCTGCTGA CTTGACCAAG AAAAACAGGC TGCCGGTGAT GGTGTGGATC 
CACGGAGGGG GGCTGATGGT GGGTGCGGCA TCAACCTATG ATGGGCTGGC CCTTGCTGCC 
CATGAAAACG TGGTGGTGGT GACCATTCAA TATCGCCTGG GCATCTGGGG ATTCTTCAGC 
ACAGGGGATG AACACAGCCG GGGGAACTGG GGTCACCTGG ACCAGGTGGC TGCCCTGCGC 
TGGGTCCAGG ACAACATTGC CAGCTTTGGA GGGAACCCAG GCTCTGTGAC CATCTTTGGA 
GAGTCAGCGG GAGGAGAAAG TGTCTCTGTT CTTGTTTTGT CTCCATTGGC CAAGAACCTC 
TTCCACCGGG CCATTTCTGA GAGTGGCGTG GCCCTCACTT CTGTTCTGGT GAAGAAAGGT 
GATGTCAAGC CCTTGGCTGA GCAAATTGCT ATCACTGCTG GGTGCAAAAC CACCACCTCT 
GCTGTCATGG TTCACTGCCT GCGACAGAAG ACGGAAGAGG AGCTCTTGGA GACGACATTG 
AAAATGAAAT TCTTATCTCT GGACTTACAG GGAGACCCCA GAGAGAGTCA ACCCCTTCTG 
GGCACTGTGA TTGATGGGAT GCTGCTGCTG AAAACACCTG AAGAGCTTCA AGCTGAAAGG 
AATTTCCACA CTGTCCCCTA CATGGTCGGA ATTAACAAGC AGGAGTTTGG CTGGTTGATT 
CCAATGTTGA TGAGCTATCC ACTCTCCGAA GGGCAACTGG ACCAGAAGAC AGCCATGTCA 
CTCCTGTGGA AGTCCTATCC CCTTGTTTGC ATTGCTAAGG AACTGATTCC AGAAGCCACT 
GAGAAATACT TAGGAGGAAC AGACGACACT GTCAAAAAGA AAGACCTGTT CCTGGACTTG 
ATAGCAGATG TGATGTTTGG TGTCCCATCT GTGATTGTGG CCCGGAACCA CAGAGATGCT 
GGAGCACCCA CCTACATGTA TGAGTTTCAG TACCGTCCAA GCTTCTCATC AGACATGAAA 
CCCAAGACGG TGATAGGAGA CCACGGGGAT GAGCTCTTCT CCGTCTTTGG GGCCCCATTT 
TTAAAAGAGG GTGCCTCAGA AGAGGAGATC AGACTTAGCA AGATGGTGAT GAAATTCTGG 
GCCAACTTTG CTCGCAATGG AAACCCCAAT GGGGAAGGGC TGCCCCACTG GCCAGAGTAC 
AACCAGAAGG AAGGGTATCT GCAGATTGGT GCCAACACCC AGGCGGCCCA GAAGCTGAAG 
GACAAAGAAG TAGCTTTCTG GACCAACCTC TTTGCCAAGA AGGCAGTGGA GAAGCCACCC 
CAGACAGAAC ACATAGAGCT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Silencing Carboxylesterase 1 in Human THP-1 Macrophages Perturbs Genes Regulated by PPARg/RXR and RAR/RXR: Downregulation of CYP27A1-LXR? Signaling.
The Biochemical journal(2018 Jan)
Mangum LC,Hou X,Borazjani A,Lee JH,Ross MK,Crow JA

Effects of Genetic Variants on Carboxylesterase 1 Gene Expression, and Clopidogrel Pharmacokinetics and Antiplatelet Effects.
Basic & clinical pharmacology & toxicology(2017 Oct)
Neuvonen M,Tarkiainen EK,Tornio A,Hirvensalo P,Tapaninen T,Paile-Hyv?rinen M,Itkonen MK,Holmberg MT,K?rj? V,M?nnist? VT,Neuvonen PJ,Pihlajam?ki J,Backman JT,Niemi M

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CES1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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