ARID3B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ARID3B
Entrez Gene ID	10620
Full Name	AT-rich interaction domain 3B
Synonyms	BDP,DRIL2
General protein information	Preferred Names AT-rich interaction domain 3B Names AT-rich interactive domain-containing protein 3B ARID domain-containing protein 3B AT rich interactive domain 3B (BRIGHT- like) bright and dead ringer protein bright-like protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 15 Map Location: 15q24.1
Summary	This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA-binding proteins. The encoded protein is homologous with two proteins that bind to the retinoblastoma gene product, and also with the mouse Bright and Drosophila dead ringer proteins. A pseudogene on chromosome 1p31 exists for this gene. Members of the ARID family have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation and possibly in chromatin structure modification. [provided by RefSeq, Jul 2008].
Disorder MIM:	612457

mRNA and Protein(s)

mRNA	Protein	Name
NM_006465.3	NP_006456.1	AT-rich interactive domain-containing protein 3B isoform 2
NM_006465.4	NP_006456.1	AT-rich interactive domain-containing protein 3B isoform 2
NM_001307939.1	NP_001294868.1	AT-rich interactive domain-containing protein 3B isoform 1

Pathways from BioSystems

Homologies

	ARID3B	XP_001099559.2
Pan troglodytes (chimpanzee)	ARID3B	XP_529731.2
Bos taurus (cattle)	ARID3B	NP_001179977.1
Mus musculus (house mouse)	Arid3b	NP_062663.1
Rattus norvegicus (Norway rat)	Arid3b	NP_001102471.1
Xenopus tropicalis (tropical clawed frog)	LOC100496484	XP_004916060.1
Homo sapiens (human)	ARID3B	NP_006456.1
Canis lupus familiaris (dog)	ARID3B	XP_544771.2
Gallus gallus (chicken)	ARID3B	NP_001243086.1

Gene Ontology
Bibliography

Related articles in PubMed

ARID3B: a Novel Regulator of the Kaposi's Sarcoma-Associated Herpesvirus Lytic Cycle.
Wood JJ, Boyne JR, Paulus C, Jackson BR, Nevels MM, Whitehouse A, Hughes DJ
Journal of virology90(20)9543-55(2016 10)

Changes in Gab2 phosphorylation and interaction partners in response to interleukin (IL)-2 stimulation in T-lymphocytes.
Osinalde N, S?nchez-Quiles V, Blagoev B, Kratchmarova I
Scientific reports623530(2016 Mar)

Critical role of ARID3B in the expression of pro-apoptotic p53-target genes and apoptosis.
Pratama E, Tian X, Lestari W, Iseki S, Ichwan SJ, Ikeda MA
Biochemical and biophysical research communications468(1-2)248-54(2015 Dec 4-11)

ARID3B increases ovarian tumor burden and is associated with a cancer stem cell gene signature.
Roy L, Samyesudhas SJ, Carrasco M, Li J, Joseph S, Dahl R, Cowden Dahl KD
Oncotarget5(18)8355-66(2014 Sep)

ARID3B expression in primary breast cancers and breast cancer-derived cell lines.
Oguz Erdogan AS, Ozdemirler N, Oyken M, Alper M, Erson-Bensan AE
Cellular oncology (Dordrecht)37(4)289-96(2014 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

A novel cellular protein (AT-rich interacting domain protein 3B [ARID3B]) that we show is able to temper lytic reactivation.
Title: ARID3B: a Novel Regulator of the Kaposi's Sarcoma-Associated Herpesvirus Lytic Cycle.

Data indicate that the most prominent proteins associating with Gab2 are PTPN11, PIK3R1 and ARID3B.
Title: Changes in Gab2 phosphorylation and interaction partners in response to interleukin (IL)-2 stimulation in T-lymphocytes.

Although ARID3B and ARID3A share overlapping functions, ARID3B play a key role in the expression of pro-apoptotic p53-target genes and apoptosis.
Title: Critical role of ARID3B in the expression of pro-apoptotic p53-target genes and apoptosis.

ARID3B boosts production CD133+ tumor stem cells and increases ovarian cancer progression in vivo.
Title: ARID3B increases ovarian tumor burden and is associated with a cancer stem cell gene signature.

Data report a positive correlation between ER positivity and nuclear ARID3B expression in primary breast cancers, along with a negative correlation with the ERBB2 status.
Title: ARID3B expression in primary breast cancers and breast cancer-derived cell lines.

The following ARID3B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ARID3B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu48062	NM_001307939.1 Latest version!	Homo sapiens AT-rich interaction domain 3B (ARID3B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu30104	NM_006465.4 Latest version!	Homo sapiens AT-rich interaction domain 3B (ARID3B), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	10-12	$307.30 $439.00
View Old Accession Versions >>
OHu30104	NM_006465.3	Homo sapiens AT-rich interaction domain 3B (ARID3B), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	10-12	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ARID3B ( NM_001307939.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001294868.1 Homo sapiens AT-rich interaction domain 3B (ARID3B), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu48062
Clone ID Related Accession (Same CDS sequence)	NM_001307939.1
Accession Version	NM_001307939.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1686bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Homo sapiens(human)
Product	AT-rich interactive domain-containing protein 3B isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC396899.1, BC041792.1, AC100835.2 and AF116846.1. On Apr 17, 2015 this sequence version replaced XM_005254129.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC041792.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCCAC TTCAGCAGCA GCAGCAGCAG CAGCAGCAAC AACAGAAGCA GCCACACCTG 
GCTCCTCTGC AGATGGATGC CAGAGAGAAG CAGGGCCAGC AGATGAGAGA AGCCCAGTTC 
TTGTATGCCC AAAAGCTGGT CACACAGCCG ACTCTCCTTT CCGCCACAGC TGGGAGACCT 
TCTGGCAGCA CTCCCTTAGG TCCCTTAGCC AGAGTTCCAC CCACCGCAGC AGTGGCCCAA 
GTGTTTGAAC GGGGCAACAT GAACTCAGAG CCTGAGGAAG AGGACGGAGG TTTGGAAGAT 
GAGGATGGGG ATGATGAAGT TGCAGAGGTG GCTGAGAAAG AAACCCAGGC TGCTTCAAAA 
TATTTTCATG TGCAGAAAGT AGCTCGCCAA GATCCCAGAG TGGCACCCAT GTCCAATCTA 
CTTCCAGCAC CAGGGCTCCC ACCACATGGA CAACAAGCTA AAGAAGACCA TACCAAAGAT 
GCTTCCAAGG CCTCACCTTC TGTCTCCACA GCAGGACAGC CGAACTGGAA TCTGGATGAG 
CAGCTCAAGC AGAATGGTGG TTTGGCCTGG AGTGATGATG CAGATGGAGG CCGGGGAAGA 
GAGATCTCTC GAGATTTTGC CAAGCTGTAT GAACTGGACG GTGATCCTGA AAGGAAAGAG 
TTCCTGGATG ACCTCTTCGT CTTTATGCAG AAGAGGGGGA CCCCCATCAA CCGAATCCCC 
ATCATGGCCA AACAGATCCT GGACCTGTAC ATGCTGTATA AGCTGGTGAC CGAGAAGGGA 
GGCCTGGTGG AGATCATCAA CAAGAAGATC TGGAGGGAGA TCACCAAAGG CCTAAACCTG 
CCCACATCCA TCACCAGCGC CGCCTTCACC CTCAGGACGC AGTACATGAA GTATCTGTAT 
GCCTATGAGT GTGAGAAGAA AGCCTTGAGT TCCCCAGCCG AGCTCCAGGC AGCAATTGAT 
GGCAACCGCA GGGAGGGCCG GCGGCCCAGC TACAGCTCCT CCCTCTTTGG CTACTCACCT 
GCTGCGGCTA CTGCTGCTGC CGCTGCCGGG GCCCCTGCCC TTCTCTCCCC ACCCAAGATC 
CGCTTTCCCA TCCTTGGGCT TGGCTCCAGC AGTGGTACCA ATACCAGTAG CCCTCGGATA 
TCCCCAGCAA CCACTCTCAG GAAAGGTGAT GGAGCCCCAG TGACAACAGT GCCTGTGCCA 
AATCGTCTGG CTGTGCCCGT GACCTTGGCA AGCCAGCAGG CTGGTACTCG GACCGCCGCA 
CTGGAGCAGC TGCGGGAGCG GCTGGAGTCA GGGGAGCCTG CTGAGAAGAA GGCATCGAGG 
CTGTCTGAGG AGGAGCAGCG CCTGGTGCAG CAGGCCTTCC AGCGCAACTT TTTCAGCATG 
GCACGGCAGC TCCCCATGAA GATCAGGATC AACGGCAGGG CAGAAGACAG AGCAGAGGCC 
TCGGCTGCAG CACTGAACCT GACCACGAGT AGCATTGGGA GCATTAACAT GTCTGTGGAC 
ATCGATGGCA CCACCTATGC AGGTGTGCTG TTTGCCCAGA AGCCTGTGGT CCACCTCATC 
ACGGGGTCTG CTCCCCAGAG CCTCGGCAGC AGCGCCAGCA GCAGCAGCAG CTCTCACTGT 
TCACCAAGTC CTACCTCATC CCGGGGCACC CCCAGCGCAG AGCCCTCCAC CAGCTGGTCC 
CTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001294868.1
CDS	232..1917
Translation	MEPLQQQQQQQQQQQKQPHLAPLQMDAREKQGQQMREAQFLYAQKLVTQPTLLSATAGRPSGSTPLGPLARVPPTAAVAQVFERGNMNSEPEEEDGGLEDEDGDDEVAEVAEKETQAASKYFHVQKVARQDPRVAPMSNLLPAPGLPPHGQQAKEDHTKDASKASPSVSTAGQPNWNLDEQLKQNGGLAWSDDADGGRGREISRDFAKLYELDGDPERKEFLDDLFVFMQKRGTPINRIPIMAKQILDLYMLYKLVTEKGGLVEIINKKIWREITKGLNLPTSITSAAFTLRTQYMKYLYAYECEKKALSSPAELQAAIDGNRREGRRPSYSSSLFGYSPAAATAAAAAGAPALLSPPKIRFPILGLGSSSGTNTSSPRISPATTLRKGDGAPVTTVPVPNRLAVPVTLASQQAGTRTAALEQLRERLESGEPAEKKASRLSEEEQRLVQQAFQRNFFSMARQLPMKIRINGRAEDRAEASAAALNLTTSSIGSINMSVDIDGTTYAGVLFAQKPVVHLITGSAPQSLGSSASSSSSSHCSPSPTSSRGTPSAEPSTSWSL

Target ORF information:

RefSeq Version	NM_001307939.1
Organism	Homo sapiens(human)
Definition	Homo sapiens AT-rich interaction domain 3B (ARID3B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001307939.1

ORF Insert Sequence:

ATGGAGCCAC TTCAGCAGCA GCAGCAGCAG CAGCAGCAAC AACAGAAGCA GCCACACCTG 
GCTCCTCTGC AGATGGATGC CAGAGAGAAG CAGGGCCAGC AGATGAGAGA AGCCCAGTTC 
TTGTATGCCC AAAAGCTGGT CACACAGCCG ACTCTCCTTT CCGCCACAGC TGGGAGACCT 
TCTGGCAGCA CTCCCTTAGG TCCCTTAGCC AGAGTTCCAC CCACCGCAGC AGTGGCCCAA 
GTGTTTGAAC GGGGCAACAT GAACTCAGAG CCTGAGGAAG AGGACGGAGG TTTGGAAGAT 
GAGGATGGGG ATGATGAAGT TGCAGAGGTG GCTGAGAAAG AAACCCAGGC TGCTTCAAAA 
TATTTTCATG TGCAGAAAGT AGCTCGCCAA GATCCCAGAG TGGCACCCAT GTCCAATCTA 
CTTCCAGCAC CAGGGCTCCC ACCACATGGA CAACAAGCTA AAGAAGACCA TACCAAAGAT 
GCTTCCAAGG CCTCACCTTC TGTCTCCACA GCAGGACAGC CGAACTGGAA TCTGGATGAG 
CAGCTCAAGC AGAATGGTGG TTTGGCCTGG AGTGATGATG CAGATGGAGG CCGGGGAAGA 
GAGATCTCTC GAGATTTTGC CAAGCTGTAT GAACTGGACG GTGATCCTGA AAGGAAAGAG 
TTCCTGGATG ACCTCTTCGT CTTTATGCAG AAGAGGGGGA CCCCCATCAA CCGAATCCCC 
ATCATGGCCA AACAGATCCT GGACCTGTAC ATGCTGTATA AGCTGGTGAC CGAGAAGGGA 
GGCCTGGTGG AGATCATCAA CAAGAAGATC TGGAGGGAGA TCACCAAAGG CCTAAACCTG 
CCCACATCCA TCACCAGCGC CGCCTTCACC CTCAGGACGC AGTACATGAA GTATCTGTAT 
GCCTATGAGT GTGAGAAGAA AGCCTTGAGT TCCCCAGCCG AGCTCCAGGC AGCAATTGAT 
GGCAACCGCA GGGAGGGCCG GCGGCCCAGC TACAGCTCCT CCCTCTTTGG CTACTCACCT 
GCTGCGGCTA CTGCTGCTGC CGCTGCCGGG GCCCCTGCCC TTCTCTCCCC ACCCAAGATC 
CGCTTTCCCA TCCTTGGGCT TGGCTCCAGC AGTGGTACCA ATACCAGTAG CCCTCGGATA 
TCCCCAGCAA CCACTCTCAG GAAAGGTGAT GGAGCCCCAG TGACAACAGT GCCTGTGCCA 
AATCGTCTGG CTGTGCCCGT GACCTTGGCA AGCCAGCAGG CTGGTACTCG GACCGCCGCA 
CTGGAGCAGC TGCGGGAGCG GCTGGAGTCA GGGGAGCCTG CTGAGAAGAA GGCATCGAGG 
CTGTCTGAGG AGGAGCAGCG CCTGGTGCAG CAGGCCTTCC AGCGCAACTT TTTCAGCATG 
GCACGGCAGC TCCCCATGAA GATCAGGATC AACGGCAGGG CAGAAGACAG AGCAGAGGCC 
TCGGCTGCAG CACTGAACCT GACCACGAGT AGCATTGGGA GCATTAACAT GTCTGTGGAC 
ATCGATGGCA CCACCTATGC AGGTGTGCTG TTTGCCCAGA AGCCTGTGGT CCACCTCATC 
ACGGGGTCTG CTCCCCAGAG CCTCGGCAGC AGCGCCAGCA GCAGCAGCAG CTCTCACTGT 
TCACCAAGTC CTACCTCATC CCGGGGCACC CCCAGCGCAG AGCCCTCCAC CAGCTGGTCC 
CTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ARID3B ( NM_006465.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_006456.1 Homo sapiens AT-rich interaction domain 3B (ARID3B), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu30104
Clone ID Related Accession (Same CDS sequence)	NM_006465.3 , NM_006465.4
Accession Version	NM_006465.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1683bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-24
Organism	Homo sapiens(human)
Product	AT-rich interactive domain-containing protein 3B isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC396899.1, AF116846.1 and AC100835.2. On Apr 17, 2015 this sequence version replaced NM_006465.2. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region compared to variant 1. It encodes isoform 2 which is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC045545.1, AF116846.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCCAC TTCAGCAGCA GCAGCAGCAG CAGCAGCAAC AACAGAAGCA GCCACACCTG 
GCTCCTCTGC AGATGGATGC CAGAGAGAAG CAGGGCCAGC AGATGAGAGA AGCCCAGTTC 
TTGTATGCCC AAAAGCTGGT CACACAGCCG ACTCTCCTTT CCGCCACAGC TGGGAGACCT 
TCTGGCAGCA CTCCCTTAGG TCCCTTAGCC AGAGTTCCAC CCACCGCAGC AGTGGCCCAA 
GTGTTTGAAC GGGGCAACAT GAACTCAGAG CCTGAGGAAG AGGACGGAGG TTTGGAAGAT 
GAGGATGGGG ATGATGAAGT TGCAGAGGTG GCTGAGAAAG AAACCCAGGC TGCTTCAAAA 
TATTTTCATG TGCAGAAAGT AGCTCGCCAA GATCCCAGAG TGGCACCCAT GTCCAATCTA 
CTTCCAGCAC CAGGGCTCCC ACCACATGGA CAACAAGCTA AAGAAGACCA TACCAAAGAT 
GCTTCCAAGG CCTCACCTTC TGTCTCCACA GCAGGACAGC CGAACTGGAA TCTGGATGAG 
CAGCTCAAGC AGAATGGTGG TTTGGCCTGG AGTGATGATG CAGATGGAGG CCGGGGAAGA 
GAGATCTCTC GAGATTTTGC CAAGCTGTAT GAACTGGACG GTGATCCTGA AAGGAAAGAG 
TTCCTGGATG ACCTCTTCGT CTTTATGCAG AAGAGGGGGA CCCCCATCAA CCGAATCCCC 
ATCATGGCCA AACAGATCCT GGACCTGTAC ATGCTGTATA AGCTGGTGAC CGAGAAGGGA 
GGCCTGGTGG AGATCATCAA CAAGAAGATC TGGAGGGAGA TCACCAAAGG CCTAAACCTG 
CCCACATCCA TCACCAGCGC CGCCTTCACC CTCAGGACGC AGTACATGAA GTATCTGTAT 
GCCTATGAGT GTGAGAAGAA AGCCTTGAGT TCCCCAGCCG AGCTCCAGGC AGCAATTGAT 
GGCAACCGCA GGGAGGGCCG GCGGCCCAGC TACAGCTCCT CCCTCTTTGG CTACTCACCT 
GCTGCGGCTA CTGCTGCTGC CGCTGCCGGG GCCCCTGCCC TTCTCTCCCC ACCCAAGATC 
CGCTTTCCCA TCCTTGGGCT TGGCTCCAGC AGTGGTACCA ATACCAGTAG CCCTCGGATA 
TCCCCAGCAA CCACTCTCAG GAAAGGTGAT GGAGCCCCAG TGACAACAGT GCCTGTGCCA 
AATCGTCTGG CTGTGCCCGT GACCTTGGCA AGCCAGCAGG CTGGTACTCG GACCGCCGCA 
CTGGAGCAGC TGCGGGAGCG GCTGGAGTCA GGGGAGCCTG CTGAGAAGAA GGCATCGAGG 
CTGTCTGAGG AGGAGCAGCG CCTGGTGCAG CAGGCCTTCC AGCGCAACTT TTTCAGCATG 
GCACGGCAGC TCCCCATGAA GATCAGGATC AACGGCAGGG AAGACAGAGC AGAGGCCTCG 
GCTGCAGCAC TGAACCTGAC CACGAGTAGC ATTGGGAGCA TTAACATGTC TGTGGACATC 
GATGGCACCA CCTATGCAGG TGTGCTGTTT GCCCAGAAGC CTGTGGTCCA CCTCATCACG 
GGGTCTGCTC CCCAGAGCCT CGGCAGCAGC GCCAGCAGCA GCAGCAGCTC TCACTGTTCA 
CCAAGTCCTA CCTCATCCCG GGGCACCCCC AGCGCAGAGC CCTCCACCAG CTGGTCCCTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006456.1
CDS	232..1914
Translation	MEPLQQQQQQQQQQQKQPHLAPLQMDAREKQGQQMREAQFLYAQKLVTQPTLLSATAGRPSGSTPLGPLARVPPTAAVAQVFERGNMNSEPEEEDGGLEDEDGDDEVAEVAEKETQAASKYFHVQKVARQDPRVAPMSNLLPAPGLPPHGQQAKEDHTKDASKASPSVSTAGQPNWNLDEQLKQNGGLAWSDDADGGRGREISRDFAKLYELDGDPERKEFLDDLFVFMQKRGTPINRIPIMAKQILDLYMLYKLVTEKGGLVEIINKKIWREITKGLNLPTSITSAAFTLRTQYMKYLYAYECEKKALSSPAELQAAIDGNRREGRRPSYSSSLFGYSPAAATAAAAAGAPALLSPPKIRFPILGLGSSSGTNTSSPRISPATTLRKGDGAPVTTVPVPNRLAVPVTLASQQAGTRTAALEQLRERLESGEPAEKKASRLSEEEQRLVQQAFQRNFFSMARQLPMKIRINGREDRAEASAAALNLTTSSIGSINMSVDIDGTTYAGVLFAQKPVVHLITGSAPQSLGSSASSSSSSHCSPSPTSSRGTPSAEPSTSWSL

Target ORF information:

RefSeq Version	NM_006465.3
Organism	Homo sapiens(human)
Definition	Homo sapiens AT-rich interaction domain 3B (ARID3B), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006465.3

ORF Insert Sequence:

ATGGAGCCAC TTCAGCAGCA GCAGCAGCAG CAGCAGCAAC AACAGAAGCA GCCACACCTG 
GCTCCTCTGC AGATGGATGC CAGAGAGAAG CAGGGCCAGC AGATGAGAGA AGCCCAGTTC 
TTGTATGCCC AAAAGCTGGT CACACAGCCG ACTCTCCTTT CCGCCACAGC TGGGAGACCT 
TCTGGCAGCA CTCCCTTAGG TCCCTTAGCC AGAGTTCCAC CCACCGCAGC AGTGGCCCAA 
GTGTTTGAAC GGGGCAACAT GAACTCAGAG CCTGAGGAAG AGGACGGAGG TTTGGAAGAT 
GAGGATGGGG ATGATGAAGT TGCAGAGGTG GCTGAGAAAG AAACCCAGGC TGCTTCAAAA 
TATTTTCATG TGCAGAAAGT AGCTCGCCAA GATCCCAGAG TGGCACCCAT GTCCAATCTA 
CTTCCAGCAC CAGGGCTCCC ACCACATGGA CAACAAGCTA AAGAAGACCA TACCAAAGAT 
GCTTCCAAGG CCTCACCTTC TGTCTCCACA GCAGGACAGC CGAACTGGAA TCTGGATGAG 
CAGCTCAAGC AGAATGGTGG TTTGGCCTGG AGTGATGATG CAGATGGAGG CCGGGGAAGA 
GAGATCTCTC GAGATTTTGC CAAGCTGTAT GAACTGGACG GTGATCCTGA AAGGAAAGAG 
TTCCTGGATG ACCTCTTCGT CTTTATGCAG AAGAGGGGGA CCCCCATCAA CCGAATCCCC 
ATCATGGCCA AACAGATCCT GGACCTGTAC ATGCTGTATA AGCTGGTGAC CGAGAAGGGA 
GGCCTGGTGG AGATCATCAA CAAGAAGATC TGGAGGGAGA TCACCAAAGG CCTAAACCTG 
CCCACATCCA TCACCAGCGC CGCCTTCACC CTCAGGACGC AGTACATGAA GTATCTGTAT 
GCCTATGAGT GTGAGAAGAA AGCCTTGAGT TCCCCAGCCG AGCTCCAGGC AGCAATTGAT 
GGCAACCGCA GGGAGGGCCG GCGGCCCAGC TACAGCTCCT CCCTCTTTGG CTACTCACCT 
GCTGCGGCTA CTGCTGCTGC CGCTGCCGGG GCCCCTGCCC TTCTCTCCCC ACCCAAGATC 
CGCTTTCCCA TCCTTGGGCT TGGCTCCAGC AGTGGTACCA ATACCAGTAG CCCTCGGATA 
TCCCCAGCAA CCACTCTCAG GAAAGGTGAT GGAGCCCCAG TGACAACAGT GCCTGTGCCA 
AATCGTCTGG CTGTGCCCGT GACCTTGGCA AGCCAGCAGG CTGGTACTCG GACCGCCGCA 
CTGGAGCAGC TGCGGGAGCG GCTGGAGTCA GGGGAGCCTG CTGAGAAGAA GGCATCGAGG 
CTGTCTGAGG AGGAGCAGCG CCTGGTGCAG CAGGCCTTCC AGCGCAACTT TTTCAGCATG 
GCACGGCAGC TCCCCATGAA GATCAGGATC AACGGCAGGG AAGACAGAGC AGAGGCCTCG 
GCTGCAGCAC TGAACCTGAC CACGAGTAGC ATTGGGAGCA TTAACATGTC TGTGGACATC 
GATGGCACCA CCTATGCAGG TGTGCTGTTT GCCCAGAAGC CTGTGGTCCA CCTCATCACG 
GGGTCTGCTC CCCAGAGCCT CGGCAGCAGC GCCAGCAGCA GCAGCAGCTC TCACTGTTCA 
CCAAGTCCTA CCTCATCCCG GGGCACCCCC AGCGCAGAGC CCTCCACCAG CTGGTCCCTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ARID3B ( NM_006465.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_006456.1 Homo sapiens AT-rich interaction domain 3B (ARID3B), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu30104
Clone ID Related Accession (Same CDS sequence)	NM_006465.3 , NM_006465.4
Accession Version	NM_006465.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1683bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-28
Organism	Homo sapiens(human)
Product	AT-rich interactive domain-containing protein 3B isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC396899.1, AF116846.1 and AC100835.2. On Jun 2, 2019 this sequence version replaced NM_006465.3. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region compared to variant 1. It encodes isoform 2 which is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF116846.1, BC045545.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAGCCAC TTCAGCAGCA GCAGCAGCAG CAGCAGCAAC AACAGAAGCA GCCACACCTG 
GCTCCTCTGC AGATGGATGC CAGAGAGAAG CAGGGCCAGC AGATGAGAGA AGCCCAGTTC 
TTGTATGCCC AAAAGCTGGT CACACAGCCG ACTCTCCTTT CCGCCACAGC TGGGAGACCT 
TCTGGCAGCA CTCCCTTAGG TCCCTTAGCC AGAGTTCCAC CCACCGCAGC AGTGGCCCAA 
GTGTTTGAAC GGGGCAACAT GAACTCAGAG CCTGAGGAAG AGGACGGAGG TTTGGAAGAT 
GAGGATGGGG ATGATGAAGT TGCAGAGGTG GCTGAGAAAG AAACCCAGGC TGCTTCAAAA 
TATTTTCATG TGCAGAAAGT AGCTCGCCAA GATCCCAGAG TGGCACCCAT GTCCAATCTA 
CTTCCAGCAC CAGGGCTCCC ACCACATGGA CAACAAGCTA AAGAAGACCA TACCAAAGAT 
GCTTCCAAGG CCTCACCTTC TGTCTCCACA GCAGGACAGC CGAACTGGAA TCTGGATGAG 
CAGCTCAAGC AGAATGGTGG TTTGGCCTGG AGTGATGATG CAGATGGAGG CCGGGGAAGA 
GAGATCTCTC GAGATTTTGC CAAGCTGTAT GAACTGGACG GTGATCCTGA AAGGAAAGAG 
TTCCTGGATG ACCTCTTCGT CTTTATGCAG AAGAGGGGGA CCCCCATCAA CCGAATCCCC 
ATCATGGCCA AACAGATCCT GGACCTGTAC ATGCTGTATA AGCTGGTGAC CGAGAAGGGA 
GGCCTGGTGG AGATCATCAA CAAGAAGATC TGGAGGGAGA TCACCAAAGG CCTAAACCTG 
CCCACATCCA TCACCAGCGC CGCCTTCACC CTCAGGACGC AGTACATGAA GTATCTGTAT 
GCCTATGAGT GTGAGAAGAA AGCCTTGAGT TCCCCAGCCG AGCTCCAGGC AGCAATTGAT 
GGCAACCGCA GGGAGGGCCG GCGGCCCAGC TACAGCTCCT CCCTCTTTGG CTACTCACCT 
GCTGCGGCTA CTGCTGCTGC CGCTGCCGGG GCCCCTGCCC TTCTCTCCCC ACCCAAGATC 
CGCTTTCCCA TCCTTGGGCT TGGCTCCAGC AGTGGTACCA ATACCAGTAG CCCTCGGATA 
TCCCCAGCAA CCACTCTCAG GAAAGGTGAT GGAGCCCCAG TGACAACAGT GCCTGTGCCA 
AATCGTCTGG CTGTGCCCGT GACCTTGGCA AGCCAGCAGG CTGGTACTCG GACCGCCGCA 
CTGGAGCAGC TGCGGGAGCG GCTGGAGTCA GGGGAGCCTG CTGAGAAGAA GGCATCGAGG 
CTGTCTGAGG AGGAGCAGCG CCTGGTGCAG CAGGCCTTCC AGCGCAACTT TTTCAGCATG 
GCACGGCAGC TCCCCATGAA GATCAGGATC AACGGCAGGG AAGACAGAGC AGAGGCCTCG 
GCTGCAGCAC TGAACCTGAC CACGAGTAGC ATTGGGAGCA TTAACATGTC TGTGGACATC 
GATGGCACCA CCTATGCAGG TGTGCTGTTT GCCCAGAAGC CTGTGGTCCA CCTCATCACG 
GGGTCTGCTC CCCAGAGCCT CGGCAGCAGC GCCAGCAGCA GCAGCAGCTC TCACTGTTCA 
CCAAGTCCTA CCTCATCCCG GGGCACCCCC AGCGCAGAGC CCTCCACCAG CTGGTCCCTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006456.1
CDS	189..1871
Translation	MEPLQQQQQQQQQQQKQPHLAPLQMDAREKQGQQMREAQFLYAQKLVTQPTLLSATAGRPSGSTPLGPLARVPPTAAVAQVFERGNMNSEPEEEDGGLEDEDGDDEVAEVAEKETQAASKYFHVQKVARQDPRVAPMSNLLPAPGLPPHGQQAKEDHTKDASKASPSVSTAGQPNWNLDEQLKQNGGLAWSDDADGGRGREISRDFAKLYELDGDPERKEFLDDLFVFMQKRGTPINRIPIMAKQILDLYMLYKLVTEKGGLVEIINKKIWREITKGLNLPTSITSAAFTLRTQYMKYLYAYECEKKALSSPAELQAAIDGNRREGRRPSYSSSLFGYSPAAATAAAAAGAPALLSPPKIRFPILGLGSSSGTNTSSPRISPATTLRKGDGAPVTTVPVPNRLAVPVTLASQQAGTRTAALEQLRERLESGEPAEKKASRLSEEEQRLVQQAFQRNFFSMARQLPMKIRINGREDRAEASAAALNLTTSSIGSINMSVDIDGTTYAGVLFAQKPVVHLITGSAPQSLGSSASSSSSSHCSPSPTSSRGTPSAEPSTSWSL

Target ORF information:

RefSeq Version	NM_006465.4
Organism	Homo sapiens(human)
Definition	Homo sapiens AT-rich interaction domain 3B (ARID3B), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006465.4

ORF Insert Sequence:

ATGGAGCCAC TTCAGCAGCA GCAGCAGCAG CAGCAGCAAC AACAGAAGCA GCCACACCTG 
GCTCCTCTGC AGATGGATGC CAGAGAGAAG CAGGGCCAGC AGATGAGAGA AGCCCAGTTC 
TTGTATGCCC AAAAGCTGGT CACACAGCCG ACTCTCCTTT CCGCCACAGC TGGGAGACCT 
TCTGGCAGCA CTCCCTTAGG TCCCTTAGCC AGAGTTCCAC CCACCGCAGC AGTGGCCCAA 
GTGTTTGAAC GGGGCAACAT GAACTCAGAG CCTGAGGAAG AGGACGGAGG TTTGGAAGAT 
GAGGATGGGG ATGATGAAGT TGCAGAGGTG GCTGAGAAAG AAACCCAGGC TGCTTCAAAA 
TATTTTCATG TGCAGAAAGT AGCTCGCCAA GATCCCAGAG TGGCACCCAT GTCCAATCTA 
CTTCCAGCAC CAGGGCTCCC ACCACATGGA CAACAAGCTA AAGAAGACCA TACCAAAGAT 
GCTTCCAAGG CCTCACCTTC TGTCTCCACA GCAGGACAGC CGAACTGGAA TCTGGATGAG 
CAGCTCAAGC AGAATGGTGG TTTGGCCTGG AGTGATGATG CAGATGGAGG CCGGGGAAGA 
GAGATCTCTC GAGATTTTGC CAAGCTGTAT GAACTGGACG GTGATCCTGA AAGGAAAGAG 
TTCCTGGATG ACCTCTTCGT CTTTATGCAG AAGAGGGGGA CCCCCATCAA CCGAATCCCC 
ATCATGGCCA AACAGATCCT GGACCTGTAC ATGCTGTATA AGCTGGTGAC CGAGAAGGGA 
GGCCTGGTGG AGATCATCAA CAAGAAGATC TGGAGGGAGA TCACCAAAGG CCTAAACCTG 
CCCACATCCA TCACCAGCGC CGCCTTCACC CTCAGGACGC AGTACATGAA GTATCTGTAT 
GCCTATGAGT GTGAGAAGAA AGCCTTGAGT TCCCCAGCCG AGCTCCAGGC AGCAATTGAT 
GGCAACCGCA GGGAGGGCCG GCGGCCCAGC TACAGCTCCT CCCTCTTTGG CTACTCACCT 
GCTGCGGCTA CTGCTGCTGC CGCTGCCGGG GCCCCTGCCC TTCTCTCCCC ACCCAAGATC 
CGCTTTCCCA TCCTTGGGCT TGGCTCCAGC AGTGGTACCA ATACCAGTAG CCCTCGGATA 
TCCCCAGCAA CCACTCTCAG GAAAGGTGAT GGAGCCCCAG TGACAACAGT GCCTGTGCCA 
AATCGTCTGG CTGTGCCCGT GACCTTGGCA AGCCAGCAGG CTGGTACTCG GACCGCCGCA 
CTGGAGCAGC TGCGGGAGCG GCTGGAGTCA GGGGAGCCTG CTGAGAAGAA GGCATCGAGG 
CTGTCTGAGG AGGAGCAGCG CCTGGTGCAG CAGGCCTTCC AGCGCAACTT TTTCAGCATG 
GCACGGCAGC TCCCCATGAA GATCAGGATC AACGGCAGGG AAGACAGAGC AGAGGCCTCG 
GCTGCAGCAC TGAACCTGAC CACGAGTAGC ATTGGGAGCA TTAACATGTC TGTGGACATC 
GATGGCACCA CCTATGCAGG TGTGCTGTTT GCCCAGAAGC CTGTGGTCCA CCTCATCACG 
GGGTCTGCTC CCCAGAGCCT CGGCAGCAGC GCCAGCAGCA GCAGCAGCTC TCACTGTTCA 
CCAAGTCCTA CCTCATCCCG GGGCACCCCC AGCGCAGAGC CCTCCACCAG CTGGTCCCTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ARID3B: a Novel Regulator of the Kaposi's Sarcoma-Associated Herpesvirus Lytic Cycle.
Journal of virology90(20)9543-55(2016 10)
Wood JJ,Boyne JR,Paulus C,Jackson BR,Nevels MM,Whitehouse A,Hughes DJ

Changes in Gab2 phosphorylation and interaction partners in response to interleukin (IL)-2 stimulation in T-lymphocytes.
Scientific reports623530(2016 Mar)
Osinalde N,S?nchez-Quiles V,Blagoev B,Kratchmarova I

Critical role of ARID3B in the expression of pro-apoptotic p53-target genes and apoptosis.
Biochemical and biophysical research communications468(1-2)248-54(2015 Dec 4-11)
Pratama E,Tian X,Lestari W,Iseki S,Ichwan SJ,Ikeda MA

ARID3B increases ovarian tumor burden and is associated with a cancer stem cell gene signature.
Oncotarget5(18)8355-66(2014 Sep)
Roy L,Samyesudhas SJ,Carrasco M,Li J,Joseph S,Dahl R,Cowden Dahl KD

ARID3B expression in primary breast cancers and breast cancer-derived cell lines.
Cellular oncology (Dordrecht)37(4)289-96(2014 Aug)
Oguz Erdogan AS,Ozdemirler N,Oyken M,Alper M,Erson-Bensan AE

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ARID3B cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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