TBL3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TBL3
Entrez Gene ID	10607
Full Name	transducin beta like 3
Synonyms	SAZD,UTP13
General protein information	Preferred Names transducin beta like 3 Names transducin beta-like protein 3 WD repeat-containing protein SAZD WD-repeat protein SAZD
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 16 Map Location: 16p13.3
Summary	The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This gene has multiple polyadenylation sites. It might have multiple alternatively spliced transcript variants but the variants have not been fully described yet. [provided by RefSeq, Jul 2008].
Disorder MIM:	605915

mRNA and Protein(s)

mRNA	Protein	Name
NM_006453.2	NP_006444.2	transducin beta-like protein 3
NM_006453.3	NP_006444.2	transducin beta-like protein 3

Pathways from BioSystems

Homologies

	TBL3	XP_001082569.2
Saccharomyces cerevisiae (baker's yeast)	UTP13	NP_013323.1
Kluyveromyces lactis	KLLA0F13244g	XP_455676.1
Eremothecium gossypii	AGOS_AGR180W	NP_986846.2
Schizosaccharomyces pombe (fission yeast)	utp13	NP_587989.2
Neurospora crassa	NCU03628	XP_961355.1
Mus musculus (house mouse)	Tbl3	NP_663371.2
Rattus norvegicus (Norway rat)	Tbl3	NP_001008278.1
Gallus gallus (chicken)	TBL3	NP_001006166.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009615	XP_318645.4
Canis lupus familiaris (dog)	TBL3	XP_547184.2
Danio rerio (zebrafish)	tbl3	NP_001007403.1
Magnaporthe oryzae (rice blast fungus)	MGG_08178	XP_003715150.1
Homo sapiens (human)	TBL3	NP_006444.2
Bos taurus (cattle)	TBL3	NP_001040084.2
Drosophila melanogaster (fruit fly)	CG1671	NP_610526.1
Arabidopsis thaliana (thale cress)	TOZ	NP_568338.2
Oryza sativa (rice)	Os04g0592700	NP_001053718.1
Xenopus tropicalis (tropical clawed frog)	tbl3	NP_001017314.1
Pan troglodytes (chimpanzee)	TBL3	XP_003314966.1
Caenorhabditis elegans (roundworm)	Y53C12B.1	NP_496100.1

Gene Ontology
Bibliography

Related articles in PubMed

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW
Cell149(6)1393-406(2012 Jun)

Association of genetic variants with hemorrhagic stroke in Japanese individuals.
Yoshida T, Kato K, Yokoi K, Oguri M, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nozawa Y, Yamada Y
International journal of molecular medicine25(4)649-56(2010 Apr)

Association of gene polymorphisms with chronic kidney disease in Japanese individuals.
Yoshida T, Kato K, Yokoi K, Oguri M, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nozawa Y, Yamada Y
International journal of molecular medicine24(4)539-47(2009 Oct)

Nucleolar proteome dynamics.
Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M
Nature433(7021)77-83(2005 Jan)

Functional proteomic analysis of human nucleolus.
Scherl A, Cout? Y, D?on C, Call? A, Kindbeiter K, Sanchez JC, Greco A, Hochstrasser D, Diaz JJ
Molecular biology of the cell13(11)4100-9(2002 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association. (HuGE Navigator)
Title: Association of genetic variants with hemorrhagic stroke in Japanese individuals.

Observational study of gene-disease association. (HuGE Navigator)
Title: Association of gene polymorphisms with chronic kidney disease in Japanese individuals.

The following TBL3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TBL3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29390	NM_006453.3 Latest version!	Homo sapiens transducin beta like 3 (TBL3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu29390	NM_006453.2	Homo sapiens transducin beta like 3 (TBL3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TBL3 ( NM_006453.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_006444.2 Homo sapiens transducin beta like 3 (TBL3), mRNA.

Price & Availability↑

CloneID	OHu29390
Clone ID Related Accession (Same CDS sequence)	NM_006453.2 , NM_006453.3
Accession Version	NM_006453.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2427bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-15
Organism	Homo sapiens(human)
Product	transducin beta-like protein 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC010231.1. On Apr 3, 2002 this sequence version replaced NM_006453.1. ##Evidence-Data-START## Transcript exon combination :: BC010231.1, SRR1803611.267072.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAGAGA CCGCGGCCGG AGTGGGCCGC TTCAAGACCA ACTATGCTGT GGAGCGCAAA 
ATTGAGCCTT TCTACAAGGG CGGAAAAGCA CAGCTGGACC AGACTGGCCA GCACCTCTTC 
TGCGTCTGTG GCACCAGAGT CAACATTCTG GAAGTGGCCT CGGGGGCCGT GCTGCGGAGT 
CTGGAGCAGG AGGACCAGGA GGACATCACT GCCTTTGACC TCAGCCCTGA CAACGAGGTG 
CTGGTGACAG CCAGTCGGGC ATTGCTGCTG GCTCAGTGGG CCTGGCAAGA GGGCAGCGTT 
ACCCGCCTGT GGAAGGCGAT ACACACGGCC CCCGTGGCCA CCATGGCCTT CGACCCCACC 
TCCACTCTGC TAGCCACAGG TGGCTGTGAT GGGGCCGTGC GCGTCTGGGA CATCGTGCGG 
CACTACGGGA CACACCACTT CCGAGGCTCG CCCGGTGTCG TGCACCTAGT GGCCTTCCAC 
CCGGACCCTA CACGCCTGCT GCTCTTCTCC TCGGCCACGG ATGCCGCCAT CCGCGTGTGG 
TCACTGCAGG ACCGGTCATG CCTGGCTGTG CTGACTGCCC ACTACAGCGC CGTCACCTCA 
CTGGCCTTCA GCGCCGACGG CCACACCATG CTCAGCTCCG GCCGTGACAA GATATGTATC 
ATCTGGGACC TTCAGAGCTG CCAGGCCACG AGGACCGTGC CTGTGTTTGA GAGCGTGGAG 
GCTGCTGTGC TGTTGCCAGA GGAGCCAGTG TCCCAGCTGG GTGTGAAGTC CCCAGGGCTG 
TACTTTCTGA CAGCTGGCGA CCAAGGCACT CTGCGCGTGT GGGAGGCAGC TTCTGGGCAG 
TGTGTGTACA CGCAGGCCCA GCCGCCGGGC CCTGGGCAGG AGCTGACCCA CTGCACCCTG 
GCACACACCG CCGGCGTGGT CCTCACCGCC ACCGCCGACC ACAACCTGTT GCTCTACGAG 
GCTCGCTCCC TGCGGCTGCA GAAACAGTTC GCTGGCTACA GTGAGGAGGT TTTGGATGTC 
CGGTTTCTTG GGCCCGAGGA CTCCCACGTT GTCGTGGCCT CCAATAGCCC CTGCCTAAAA 
GTGTTTGAGC TGCAGACGTC AGCCTGCCAG ATCCTCCACG GCCACACGGA TATCGTCCTG 
GCCCTGGATG TGTTCCGGAA GGGGTGGCTC TTTGCCAGCT GTGCCAAGGA TCAGAGCGTC 
CGTATCTGGA GAATGAACAA GGCTGGCCAG GTGATGTGCG TGGCTCAGGG TTCCGGTCAC 
ACACACAGTG TGGGCACCGT CTGCTGCTCT AGGCTGAAGG AGTCCTTCCT GGTGACAGGC 
AGCCAGGACT GCACTGTGAA GCTGTGGCCT CTTCCCAAAG CCTTGCTGTC CAAGAACACA 
GCCCCAGACA ACGGCCCTAT CCTCCTGCAG GCCCAGACCA CTCAGCGCTG CCATGATAAG 
GACATCAACA GCGTGGCTAT TGCCCCCAAC GACAAGCTGC TGGCCACAGG CTCACAGGAC 
CGCACGGCCA AGCTCTGGGC CCTGCCACAG TGCCAGCTGC TGGGTGTCTT CTCAGGCCAC 
CGGCGTGGCC TCTGGTGCGT CCAGTTCTCT CCCATGGACC AGGTGCTGGC CACGGCCTCA 
GCTGATGGCA CCATCAAGCT CTGGGCACTC CAGGACTTCA GCTGTCTCAA GACATTTGAG 
GGGCACGATG CTTCTGTGCT GAAGGTGGCC TTTGTGAGCC GTGGCACGCA GCTGCTGTCC 
AGCGGTTCGG ATGGCCTCGT GAAGCTCTGG ACCATCAAGA ACAACGAGTG TGTGCGGACG 
CTGGATGCCC ACGAGGACAA GGTCTGGGGG CTGCACTGCA GCCGGCTGGA CGACCACGCC 
CTCACTGGGG CCAGTGACTC CCGAGTCATC CTCTGGAAGG ATGTGACCGA GGCGGAGCAG 
GCAGAGGAGC AGGCCAGGCA AGAGGAGCAG GTGGTCAGGC AGCAAGAGCT GGACAACCTG 
CTGCATGAGA AGCGGTACCT GCGGGCGCTG GGCCTGGCCA TCTCCCTGGA TCGGCCCCAC 
ACCGTGCTGA CTGTCATCCA GGCCATCCGG AGGGACCCTG AGGCCTGCGA GAAGCTGGAA 
GCCACCATGC TCCGACTGCG GCGCGACCAG AAAGAGGCCC TGCTGCGCTT CTGCGTCACG 
TGGAACACCA ACTCGCGGCA CTGCCACGAG GCCCAGGCCG TGCTGGGTGT GCTCTTGAGG 
CGAGAGGCCC CCGAGGAGCT GCTGGCCTAC GAAGGCGTGC GGGCAGCGCT TGAGGCCCTG 
CTGCCCTACA CTGAGCGGCA CTTTCAGCGG CTCAGCAGGA CCCTCCAGGC CGCCGCTTTC 
TTGGACTTCC TGTGGCACAA CATGAAGCTC CCTGTGCCGG CCGCCGCCCC CACCCCCTGG 
GAAACCCATA AAGGCGCACT GCCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006444.2
CDS	103..2529
Translation	MAETAAGVGRFKTNYAVERKIEPFYKGGKAQLDQTGQHLFCVCGTRVNILEVASGAVLRSLEQEDQEDITAFDLSPDNEVLVTASRALLLAQWAWQEGSVTRLWKAIHTAPVATMAFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVEAAVLLPEEPVSQLGVKSPGLYFLTAGDQGTLRVWEAASGQCVYTQAQPPGPGQELTHCTLAHTAGVVLTATADHNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLKVFELQTSACQILHGHTDIVLALDVFRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGTVCCSRLKESFLVTGSQDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDKVWGLHCSRLDDHALTGASDSRVILWKDVTEAEQAEEQARQEEQVVRQQELDNLLHEKRYLRALGLAISLDRPHTVLTVIQAIRRDPEACEKLEATMLRLRRDQKEALLRFCVTWNTNSRHCHEAQAVLGVLLRREAPEELLAYEGVRAALEALLPYTERHFQRLSRTLQAAAFLDFLWHNMKLPVPAAAPTPWETHKGALP

Target ORF information:

RefSeq Version	NM_006453.2
Organism	Homo sapiens(human)
Definition	Homo sapiens transducin beta like 3 (TBL3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006453.2

ORF Insert Sequence:

ATGGCAGAGA CCGCGGCCGG AGTGGGCCGC TTCAAGACCA ACTATGCTGT GGAGCGCAAA 
ATTGAGCCTT TCTACAAGGG CGGAAAAGCA CAGCTGGACC AGACTGGCCA GCACCTCTTC 
TGCGTCTGTG GCACCAGAGT CAACATTCTG GAAGTGGCCT CGGGGGCCGT GCTGCGGAGT 
CTGGAGCAGG AGGACCAGGA GGACATCACT GCCTTTGACC TCAGCCCTGA CAACGAGGTG 
CTGGTGACAG CCAGTCGGGC ATTGCTGCTG GCTCAGTGGG CCTGGCAAGA GGGCAGCGTT 
ACCCGCCTGT GGAAGGCGAT ACACACGGCC CCCGTGGCCA CCATGGCCTT CGACCCCACC 
TCCACTCTGC TAGCCACAGG TGGCTGTGAT GGGGCCGTGC GCGTCTGGGA CATCGTGCGG 
CACTACGGGA CACACCACTT CCGAGGCTCG CCCGGTGTCG TGCACCTAGT GGCCTTCCAC 
CCGGACCCTA CACGCCTGCT GCTCTTCTCC TCGGCCACGG ATGCCGCCAT CCGCGTGTGG 
TCACTGCAGG ACCGGTCATG CCTGGCTGTG CTGACTGCCC ACTACAGCGC CGTCACCTCA 
CTGGCCTTCA GCGCCGACGG CCACACCATG CTCAGCTCCG GCCGTGACAA GATATGTATC 
ATCTGGGACC TTCAGAGCTG CCAGGCCACG AGGACCGTGC CTGTGTTTGA GAGCGTGGAG 
GCTGCTGTGC TGTTGCCAGA GGAGCCAGTG TCCCAGCTGG GTGTGAAGTC CCCAGGGCTG 
TACTTTCTGA CAGCTGGCGA CCAAGGCACT CTGCGCGTGT GGGAGGCAGC TTCTGGGCAG 
TGTGTGTACA CGCAGGCCCA GCCGCCGGGC CCTGGGCAGG AGCTGACCCA CTGCACCCTG 
GCACACACCG CCGGCGTGGT CCTCACCGCC ACCGCCGACC ACAACCTGTT GCTCTACGAG 
GCTCGCTCCC TGCGGCTGCA GAAACAGTTC GCTGGCTACA GTGAGGAGGT TTTGGATGTC 
CGGTTTCTTG GGCCCGAGGA CTCCCACGTT GTCGTGGCCT CCAATAGCCC CTGCCTAAAA 
GTGTTTGAGC TGCAGACGTC AGCCTGCCAG ATCCTCCACG GCCACACGGA TATCGTCCTG 
GCCCTGGATG TGTTCCGGAA GGGGTGGCTC TTTGCCAGCT GTGCCAAGGA TCAGAGCGTC 
CGTATCTGGA GAATGAACAA GGCTGGCCAG GTGATGTGCG TGGCTCAGGG TTCCGGTCAC 
ACACACAGTG TGGGCACCGT CTGCTGCTCT AGGCTGAAGG AGTCCTTCCT GGTGACAGGC 
AGCCAGGACT GCACTGTGAA GCTGTGGCCT CTTCCCAAAG CCTTGCTGTC CAAGAACACA 
GCCCCAGACA ACGGCCCTAT CCTCCTGCAG GCCCAGACCA CTCAGCGCTG CCATGATAAG 
GACATCAACA GCGTGGCTAT TGCCCCCAAC GACAAGCTGC TGGCCACAGG CTCACAGGAC 
CGCACGGCCA AGCTCTGGGC CCTGCCACAG TGCCAGCTGC TGGGTGTCTT CTCAGGCCAC 
CGGCGTGGCC TCTGGTGCGT CCAGTTCTCT CCCATGGACC AGGTGCTGGC CACGGCCTCA 
GCTGATGGCA CCATCAAGCT CTGGGCACTC CAGGACTTCA GCTGTCTCAA GACATTTGAG 
GGGCACGATG CTTCTGTGCT GAAGGTGGCC TTTGTGAGCC GTGGCACGCA GCTGCTGTCC 
AGCGGTTCGG ATGGCCTCGT GAAGCTCTGG ACCATCAAGA ACAACGAGTG TGTGCGGACG 
CTGGATGCCC ACGAGGACAA GGTCTGGGGG CTGCACTGCA GCCGGCTGGA CGACCACGCC 
CTCACTGGGG CCAGTGACTC CCGAGTCATC CTCTGGAAGG ATGTGACCGA GGCGGAGCAG 
GCAGAGGAGC AGGCCAGGCA AGAGGAGCAG GTGGTCAGGC AGCAAGAGCT GGACAACCTG 
CTGCATGAGA AGCGGTACCT GCGGGCGCTG GGCCTGGCCA TCTCCCTGGA TCGGCCCCAC 
ACCGTGCTGA CTGTCATCCA GGCCATCCGG AGGGACCCTG AGGCCTGCGA GAAGCTGGAA 
GCCACCATGC TCCGACTGCG GCGCGACCAG AAAGAGGCCC TGCTGCGCTT CTGCGTCACG 
TGGAACACCA ACTCGCGGCA CTGCCACGAG GCCCAGGCCG TGCTGGGTGT GCTCTTGAGG 
CGAGAGGCCC CCGAGGAGCT GCTGGCCTAC GAAGGCGTGC GGGCAGCGCT TGAGGCCCTG 
CTGCCCTACA CTGAGCGGCA CTTTCAGCGG CTCAGCAGGA CCCTCCAGGC CGCCGCTTTC 
TTGGACTTCC TGTGGCACAA CATGAAGCTC CCTGTGCCGG CCGCCGCCCC CACCCCCTGG 
GAAACCCATA AAGGCGCACT GCCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TBL3 ( NM_006453.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_006444.2 Homo sapiens transducin beta like 3 (TBL3), mRNA.

Price & Availability↑

CloneID	OHu29390
Clone ID Related Accession (Same CDS sequence)	NM_006453.2 , NM_006453.3
Accession Version	NM_006453.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2427bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-24
Organism	Homo sapiens(human)
Product	transducin beta-like protein 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC005363.1, BC010231.1 and AC005606.3. On May 17, 2019 this sequence version replaced NM_006453.2. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.260451.1, SRR1803614.197805.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000568546.6/ ENSP00000454836.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCAGAGA CCGCGGCCGG AGTGGGCCGC TTCAAGACCA ACTATGCTGT GGAGCGCAAA 
ATTGAGCCTT TCTACAAGGG CGGAAAAGCA CAGCTGGACC AGACTGGCCA GCACCTCTTC 
TGCGTCTGTG GCACCAGAGT CAACATTCTG GAAGTGGCCT CGGGGGCCGT GCTGCGGAGT 
CTGGAGCAGG AGGACCAGGA GGACATCACT GCCTTTGACC TCAGCCCTGA CAACGAGGTG 
CTGGTGACAG CCAGTCGGGC ATTGCTGCTG GCTCAGTGGG CCTGGCAAGA GGGCAGCGTT 
ACCCGCCTGT GGAAGGCGAT ACACACGGCC CCCGTGGCCA CCATGGCCTT CGACCCCACC 
TCCACTCTGC TAGCCACAGG TGGCTGTGAT GGGGCCGTGC GCGTCTGGGA CATCGTGCGG 
CACTACGGGA CACACCACTT CCGAGGCTCG CCCGGTGTCG TGCACCTAGT GGCCTTCCAC 
CCGGACCCTA CACGCCTGCT GCTCTTCTCC TCGGCCACGG ATGCCGCCAT CCGCGTGTGG 
TCACTGCAGG ACCGGTCATG CCTGGCTGTG CTGACTGCCC ACTACAGCGC CGTCACCTCA 
CTGGCCTTCA GCGCCGACGG CCACACCATG CTCAGCTCCG GCCGTGACAA GATATGTATC 
ATCTGGGACC TTCAGAGCTG CCAGGCCACG AGGACCGTGC CTGTGTTTGA GAGCGTGGAG 
GCTGCTGTGC TGTTGCCAGA GGAGCCAGTG TCCCAGCTGG GTGTGAAGTC CCCAGGGCTG 
TACTTTCTGA CAGCTGGCGA CCAAGGCACT CTGCGCGTGT GGGAGGCAGC TTCTGGGCAG 
TGTGTGTACA CGCAGGCCCA GCCGCCGGGC CCTGGGCAGG AGCTGACCCA CTGCACCCTG 
GCACACACCG CCGGCGTGGT CCTCACCGCC ACCGCCGACC ACAACCTGTT GCTCTACGAG 
GCTCGCTCCC TGCGGCTGCA GAAACAGTTC GCTGGCTACA GTGAGGAGGT TTTGGATGTC 
CGGTTTCTTG GGCCCGAGGA CTCCCACGTT GTCGTGGCCT CCAATAGCCC CTGCCTAAAA 
GTGTTTGAGC TGCAGACGTC AGCCTGCCAG ATCCTCCACG GCCACACGGA TATCGTCCTG 
GCCCTGGATG TGTTCCGGAA GGGGTGGCTC TTTGCCAGCT GTGCCAAGGA TCAGAGCGTC 
CGTATCTGGA GAATGAACAA GGCTGGCCAG GTGATGTGCG TGGCTCAGGG TTCCGGTCAC 
ACACACAGTG TGGGCACCGT CTGCTGCTCT AGGCTGAAGG AGTCCTTCCT GGTGACAGGC 
AGCCAGGACT GCACTGTGAA GCTGTGGCCT CTTCCCAAAG CCTTGCTGTC CAAGAACACA 
GCCCCAGACA ACGGCCCTAT CCTCCTGCAG GCCCAGACCA CTCAGCGCTG CCATGATAAG 
GACATCAACA GCGTGGCTAT TGCCCCCAAC GACAAGCTGC TGGCCACAGG CTCACAGGAC 
CGCACGGCCA AGCTCTGGGC CCTGCCACAG TGCCAGCTGC TGGGTGTCTT CTCAGGCCAC 
CGGCGTGGCC TCTGGTGCGT CCAGTTCTCT CCCATGGACC AGGTGCTGGC CACGGCCTCA 
GCTGATGGCA CCATCAAGCT CTGGGCACTC CAGGACTTCA GCTGTCTCAA GACATTTGAG 
GGGCACGATG CTTCTGTGCT GAAGGTGGCC TTTGTGAGCC GTGGCACGCA GCTGCTGTCC 
AGCGGTTCGG ATGGCCTCGT GAAGCTCTGG ACCATCAAGA ACAACGAGTG TGTGCGGACG 
CTGGATGCCC ACGAGGACAA GGTCTGGGGG CTGCACTGCA GCCGGCTGGA CGACCACGCC 
CTCACTGGGG CCAGTGACTC CCGAGTCATC CTCTGGAAGG ATGTGACCGA GGCGGAGCAG 
GCAGAGGAGC AGGCCAGGCA AGAGGAGCAG GTGGTCAGGC AGCAAGAGCT GGACAACCTG 
CTGCATGAGA AGCGGTACCT GCGGGCGCTG GGCCTGGCCA TCTCCCTGGA TCGGCCCCAC 
ACCGTGCTGA CTGTCATCCA GGCCATCCGG AGGGACCCTG AGGCCTGCGA GAAGCTGGAA 
GCCACCATGC TCCGACTGCG GCGCGACCAG AAAGAGGCCC TGCTGCGCTT CTGCGTCACG 
TGGAACACCA ACTCGCGGCA CTGCCACGAG GCCCAGGCCG TGCTGGGTGT GCTCTTGAGG 
CGAGAGGCCC CCGAGGAGCT GCTGGCCTAC GAAGGCGTGC GGGCAGCGCT TGAGGCCCTG 
CTGCCCTACA CTGAGCGGCA CTTTCAGCGG CTCAGCAGGA CCCTCCAGGC CGCCGCTTTC 
TTGGACTTCC TGTGGCACAA CATGAAGCTC CCTGTGCCGG CCGCCGCCCC CACCCCCTGG 
GAAACCCATA AAGGCGCACT GCCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006444.2
CDS	113..2539
Translation	MAETAAGVGRFKTNYAVERKIEPFYKGGKAQLDQTGQHLFCVCGTRVNILEVASGAVLRSLEQEDQEDITAFDLSPDNEVLVTASRALLLAQWAWQEGSVTRLWKAIHTAPVATMAFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVEAAVLLPEEPVSQLGVKSPGLYFLTAGDQGTLRVWEAASGQCVYTQAQPPGPGQELTHCTLAHTAGVVLTATADHNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLKVFELQTSACQILHGHTDIVLALDVFRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGTVCCSRLKESFLVTGSQDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDKVWGLHCSRLDDHALTGASDSRVILWKDVTEAEQAEEQARQEEQVVRQQELDNLLHEKRYLRALGLAISLDRPHTVLTVIQAIRRDPEACEKLEATMLRLRRDQKEALLRFCVTWNTNSRHCHEAQAVLGVLLRREAPEELLAYEGVRAALEALLPYTERHFQRLSRTLQAAAFLDFLWHNMKLPVPAAAPTPWETHKGALP

Target ORF information:

RefSeq Version	NM_006453.3
Organism	Homo sapiens(human)
Definition	Homo sapiens transducin beta like 3 (TBL3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006453.3

ORF Insert Sequence:

ATGGCAGAGA CCGCGGCCGG AGTGGGCCGC TTCAAGACCA ACTATGCTGT GGAGCGCAAA 
ATTGAGCCTT TCTACAAGGG CGGAAAAGCA CAGCTGGACC AGACTGGCCA GCACCTCTTC 
TGCGTCTGTG GCACCAGAGT CAACATTCTG GAAGTGGCCT CGGGGGCCGT GCTGCGGAGT 
CTGGAGCAGG AGGACCAGGA GGACATCACT GCCTTTGACC TCAGCCCTGA CAACGAGGTG 
CTGGTGACAG CCAGTCGGGC ATTGCTGCTG GCTCAGTGGG CCTGGCAAGA GGGCAGCGTT 
ACCCGCCTGT GGAAGGCGAT ACACACGGCC CCCGTGGCCA CCATGGCCTT CGACCCCACC 
TCCACTCTGC TAGCCACAGG TGGCTGTGAT GGGGCCGTGC GCGTCTGGGA CATCGTGCGG 
CACTACGGGA CACACCACTT CCGAGGCTCG CCCGGTGTCG TGCACCTAGT GGCCTTCCAC 
CCGGACCCTA CACGCCTGCT GCTCTTCTCC TCGGCCACGG ATGCCGCCAT CCGCGTGTGG 
TCACTGCAGG ACCGGTCATG CCTGGCTGTG CTGACTGCCC ACTACAGCGC CGTCACCTCA 
CTGGCCTTCA GCGCCGACGG CCACACCATG CTCAGCTCCG GCCGTGACAA GATATGTATC 
ATCTGGGACC TTCAGAGCTG CCAGGCCACG AGGACCGTGC CTGTGTTTGA GAGCGTGGAG 
GCTGCTGTGC TGTTGCCAGA GGAGCCAGTG TCCCAGCTGG GTGTGAAGTC CCCAGGGCTG 
TACTTTCTGA CAGCTGGCGA CCAAGGCACT CTGCGCGTGT GGGAGGCAGC TTCTGGGCAG 
TGTGTGTACA CGCAGGCCCA GCCGCCGGGC CCTGGGCAGG AGCTGACCCA CTGCACCCTG 
GCACACACCG CCGGCGTGGT CCTCACCGCC ACCGCCGACC ACAACCTGTT GCTCTACGAG 
GCTCGCTCCC TGCGGCTGCA GAAACAGTTC GCTGGCTACA GTGAGGAGGT TTTGGATGTC 
CGGTTTCTTG GGCCCGAGGA CTCCCACGTT GTCGTGGCCT CCAATAGCCC CTGCCTAAAA 
GTGTTTGAGC TGCAGACGTC AGCCTGCCAG ATCCTCCACG GCCACACGGA TATCGTCCTG 
GCCCTGGATG TGTTCCGGAA GGGGTGGCTC TTTGCCAGCT GTGCCAAGGA TCAGAGCGTC 
CGTATCTGGA GAATGAACAA GGCTGGCCAG GTGATGTGCG TGGCTCAGGG TTCCGGTCAC 
ACACACAGTG TGGGCACCGT CTGCTGCTCT AGGCTGAAGG AGTCCTTCCT GGTGACAGGC 
AGCCAGGACT GCACTGTGAA GCTGTGGCCT CTTCCCAAAG CCTTGCTGTC CAAGAACACA 
GCCCCAGACA ACGGCCCTAT CCTCCTGCAG GCCCAGACCA CTCAGCGCTG CCATGATAAG 
GACATCAACA GCGTGGCTAT TGCCCCCAAC GACAAGCTGC TGGCCACAGG CTCACAGGAC 
CGCACGGCCA AGCTCTGGGC CCTGCCACAG TGCCAGCTGC TGGGTGTCTT CTCAGGCCAC 
CGGCGTGGCC TCTGGTGCGT CCAGTTCTCT CCCATGGACC AGGTGCTGGC CACGGCCTCA 
GCTGATGGCA CCATCAAGCT CTGGGCACTC CAGGACTTCA GCTGTCTCAA GACATTTGAG 
GGGCACGATG CTTCTGTGCT GAAGGTGGCC TTTGTGAGCC GTGGCACGCA GCTGCTGTCC 
AGCGGTTCGG ATGGCCTCGT GAAGCTCTGG ACCATCAAGA ACAACGAGTG TGTGCGGACG 
CTGGATGCCC ACGAGGACAA GGTCTGGGGG CTGCACTGCA GCCGGCTGGA CGACCACGCC 
CTCACTGGGG CCAGTGACTC CCGAGTCATC CTCTGGAAGG ATGTGACCGA GGCGGAGCAG 
GCAGAGGAGC AGGCCAGGCA AGAGGAGCAG GTGGTCAGGC AGCAAGAGCT GGACAACCTG 
CTGCATGAGA AGCGGTACCT GCGGGCGCTG GGCCTGGCCA TCTCCCTGGA TCGGCCCCAC 
ACCGTGCTGA CTGTCATCCA GGCCATCCGG AGGGACCCTG AGGCCTGCGA GAAGCTGGAA 
GCCACCATGC TCCGACTGCG GCGCGACCAG AAAGAGGCCC TGCTGCGCTT CTGCGTCACG 
TGGAACACCA ACTCGCGGCA CTGCCACGAG GCCCAGGCCG TGCTGGGTGT GCTCTTGAGG 
CGAGAGGCCC CCGAGGAGCT GCTGGCCTAC GAAGGCGTGC GGGCAGCGCT TGAGGCCCTG 
CTGCCCTACA CTGAGCGGCA CTTTCAGCGG CTCAGCAGGA CCCTCCAGGC CGCCGCTTTC 
TTGGACTTCC TGTGGCACAA CATGAAGCTC CCTGTGCCGG CCGCCGCCCC CACCCCCTGG 
GAAACCCATA AAGGCGCACT GCCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Cell149(6)1393-406(2012 Jun)
Castello A,Fischer B,Eichelbaum K,Horos R,Beckmann BM,Strein C,Davey NE,Humphreys DT,Preiss T,Steinmetz LM,Krijgsveld J,Hentze MW

Association of genetic variants with hemorrhagic stroke in Japanese individuals.
International journal of molecular medicine25(4)649-56(2010 Apr)
Yoshida T,Kato K,Yokoi K,Oguri M,Watanabe S,Metoki N,Yoshida H,Satoh K,Aoyagi Y,Nozawa Y,Yamada Y

Association of gene polymorphisms with chronic kidney disease in Japanese individuals.
International journal of molecular medicine24(4)539-47(2009 Oct)
Yoshida T,Kato K,Yokoi K,Oguri M,Watanabe S,Metoki N,Yoshida H,Satoh K,Aoyagi Y,Nozawa Y,Yamada Y

Nucleolar proteome dynamics.
Nature433(7021)77-83(2005 Jan)
Andersen JS,Lam YW,Leung AK,Ong SE,Lyon CE,Lamond AI,Mann M

Functional proteomic analysis of human nucleolus.
Molecular biology of the cell13(11)4100-9(2002 Nov)
Scherl A,Cout? Y,D?on C,Call? A,Kindbeiter K,Sanchez JC,Greco A,Hochstrasser D,Diaz JJ

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TBL3 cDNA ORF clone, Homo sapiens(human)

Gene

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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