DNPH1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	DNPH1
Entrez Gene ID	10591
Full Name	2'-deoxynucleoside 5'-phosphate N-hydrolase 1
Synonyms	C6orf108,RCL,dJ330M21.3
General protein information	Preferred Names 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 Names 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 c-Myc-responsive protein RCL c-Myc-responsive protein Rcl deoxyribonucleoside 5'-monophosphate N-glycosidase putative c-Myc-responsive
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6p21.1
Summary	This gene was identified on the basis of its stimulation by c-Myc protein. The latter is a transcription factor that participates in the regulation of cell proliferation, differentiation, and apoptosis. The exact function of this gene is not known but studies in rat suggest a role in cellular proliferation and c-Myc-mediated transformation. Two alternative transcripts encoding different proteins have been described. [provided by RefSeq, Jul 2008].

mRNA and Protein(s)

mRNA	Protein	Name
NM_199184.1	NP_954653.1	2'-deoxynucleoside 5'-phosphate N-hydrolase 1 isoform 2
NM_199184.2	NP_954653.1	2'-deoxynucleoside 5'-phosphate N-hydrolase 1 isoform 2
NM_006443.3	NP_006434.1	2'-deoxynucleoside 5'-phosphate N-hydrolase 1 isoform 1
NM_006443.2	NP_006434.1	2'-deoxynucleoside 5'-phosphate N-hydrolase 1 isoform 1

Pathways from BioSystems

Homologies

	C4H6orf108	XP_001093715.1
Mus musculus (house mouse)	Dnph1	NP_997044.2
Rattus norvegicus (Norway rat)	Dnph1	NP_598209.1
Canis lupus familiaris (dog)	C12H6orf108	XP_538931.3
Pan troglodytes (chimpanzee)	C6H6orf108	XP_518907.1
Bos taurus (cattle)	C23H6orf108	XP_003587733.2
Danio rerio (zebrafish)	dnph1	NP_001156671.1
Homo sapiens (human)	DNPH1	NP_006434.1

Gene Ontology
Bibliography

Related articles in PubMed

6-(Hetero)Arylpurine nucleotides as inhibitors of the oncogenic target DNPH1: synthesis, structural studies and cytotoxic activities.
Amiable C, Paoletti J, Haouz A, Padilla A, Labesse G, Kaminski PA, Pochet S
European journal of medicinal chemistry85418-37(2014 Oct)

Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects.
Deng X, Sabino EC, Cunha-Neto E, Ribeiro AL, Ianni B, Mady C, Busch MP, Seielstad M,
PloS one8(11)e79629(2013)

Analysis of proteomic changes induced upon cellular differentiation of the human intestinal cell line Caco-2.
Buhrke T, Lengler I, Lampen A
Development, growth & differentiation53(3)411-26(2011 Apr)

Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells.
Lee OH, Kim H, He Q, Baek HJ, Yang D, Chen LY, Liang J, Chae HK, Safari A, Liu D, Songyang Z
Molecular & cellular proteomics : MCP10(2)M110.001628(2011 Feb)

Probing the active site of the deoxynucleotide N-hydrolase Rcl encoded by the rat gene c6orf108.
Dupouy C, Zhang C, Padilla A, Pochet S, Kaminski PA
The Journal of biological chemistry285(53)41806-14(2010 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

analysis of human deoxynucleotide N-hydrolase Rcl and rat gene c6orf108
Title: Probing the active site of the deoxynucleotide N-hydrolase Rcl encoded by the rat gene c6orf108.

characterization of the human Rcl gene, we cloned its promoter, Rcl is a bona fide target gene of ETV1.
Title: Rcl is a novel ETV1/ER81 target gene upregulated in breast tumors.

The following DNPH1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DNPH1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu13024	NM_199184.2 Latest version!	Homo sapiens 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 (DNPH1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu13145	NM_006443.3 Latest version!	Homo sapiens 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 (DNPH1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu13024	NM_199184.1	Homo sapiens 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 (DNPH1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu13145	NM_006443.2	Homo sapiens 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 (DNPH1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

DNPH1 ( NM_199184.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_954653.1 Homo sapiens 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 (DNPH1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu13024
Clone ID Related Accession (Same CDS sequence)	NM_199184.1 , NM_199184.2
Accession Version	NM_199184.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 447bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-15
Organism	Homo sapiens(human)
Product	2'-deoxynucleoside 5'-phosphate N-hydrolase 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF040105.1, BC011683.2 and BQ052226.1. Transcript Variant: This variant (2) includes an additional segment in the 3' coding region, compared to variant 1, that causes a frameshift. The resulting protein (isoform 2) has a shorter and distinct C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: ERR279836.7988.1, SRR1163655.449615.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGCTG CCATGGTGCC GGGGCGCAGC GAGAGCTGGG AGCGCGGGGA GCCTGGCCGC 
CCGGCCCTGT ACTTCTGCGG GAGCATTCGC GGCGGACGCG AGGACAGGAC GCTGTACGAG 
CGGATCGTGT CTCGGCTGCG GCGATTCGGG ACAGTGCTCA CCGAGCACGT GGCGGCCGCC 
GAGCTGGGCG CGCGCGGGGA AGAGGCTGCT GGGGGTGACA GGCTCATCCA TGAGCAGGAC 
CTGGAGTGGC TGCAGCAGGC GGACGTGGTC GTGGCAGAAG TGACACAGCC ATCCTTGGGT 
GTAGGCTATG AGCTGGGCCG GGCCGTGGCC TTTAACAAGC GGATCCTGTG CCTGTTCCGC 
CCGCAGTCTG GCCGCGGTGA GCACCCCAAG CCTCCCTCCT GGCTTTCTAT GGACCCAGCC 
CTCAGCTCCT TCCCTGGTGG GCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_954653.1
CDS	18..464
Translation	MAAAMVPGRSESWERGEPGRPALYFCGSIRGGREDRTLYERIVSRLRRFGTVLTEHVAAAELGARGEEAAGGDRLIHEQDLEWLQQADVVVAEVTQPSLGVGYELGRAVAFNKRILCLFRPQSGRGEHPKPPSWLSMDPALSSFPGGL

Target ORF information:

RefSeq Version	NM_199184.1
Organism	Homo sapiens(human)
Definition	Homo sapiens 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 (DNPH1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_199184.1

ORF Insert Sequence:

ATGGCTGCTG CCATGGTGCC GGGGCGCAGC GAGAGCTGGG AGCGCGGGGA GCCTGGCCGC 
CCGGCCCTGT ACTTCTGCGG GAGCATTCGC GGCGGACGCG AGGACAGGAC GCTGTACGAG 
CGGATCGTGT CTCGGCTGCG GCGATTCGGG ACAGTGCTCA CCGAGCACGT GGCGGCCGCC 
GAGCTGGGCG CGCGCGGGGA AGAGGCTGCT GGGGGTGACA GGCTCATCCA TGAGCAGGAC 
CTGGAGTGGC TGCAGCAGGC GGACGTGGTC GTGGCAGAAG TGACACAGCC ATCCTTGGGT 
GTAGGCTATG AGCTGGGCCG GGCCGTGGCC TTTAACAAGC GGATCCTGTG CCTGTTCCGC 
CCGCAGTCTG GCCGCGGTGA GCACCCCAAG CCTCCCTCCT GGCTTTCTAT GGACCCAGCC 
CTCAGCTCCT TCCCTGGTGG GCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DNPH1 ( NM_199184.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_954653.1 Homo sapiens 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 (DNPH1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu13024
Clone ID Related Accession (Same CDS sequence)	NM_199184.1 , NM_199184.2
Accession Version	NM_199184.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 447bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-01
Organism	Homo sapiens(human)
Product	2'-deoxynucleoside 5'-phosphate N-hydrolase 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL133375.25, AF040105.1, BC011683.2 and BQ052226.1. On Jun 2, 2019 this sequence version replaced NM_199184.1. Transcript Variant: This variant (2) includes an additional segment in the 3' coding region, compared to variant 1, that causes a frameshift. The resulting protein (isoform 2) has a shorter and distinct C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: ERR279836.7988.1, ERR1172420.2497.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGCTG CCATGGTGCC GGGGCGCAGC GAGAGCTGGG AGCGCGGGGA GCCTGGCCGC 
CCGGCCCTGT ACTTCTGCGG GAGCATTCGC GGCGGACGCG AGGACAGGAC GCTGTACGAG 
CGGATCGTGT CTCGGCTGCG GCGATTCGGG ACAGTGCTCA CCGAGCACGT GGCGGCCGCC 
GAGCTGGGCG CGCGCGGGGA AGAGGCTGCT GGGGGTGACA GGCTCATCCA TGAGCAGGAC 
CTGGAGTGGC TGCAGCAGGC GGACGTGGTC GTGGCAGAAG TGACACAGCC ATCCTTGGGT 
GTAGGCTATG AGCTGGGCCG GGCCGTGGCC TTTAACAAGC GGATCCTGTG CCTGTTCCGC 
CCGCAGTCTG GCCGCGGTGA GCACCCCAAG CCTCCCTCCT GGCTTTCTAT GGACCCAGCC 
CTCAGCTCCT TCCCTGGTGG GCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_954653.1
CDS	26..472
Translation	MAAAMVPGRSESWERGEPGRPALYFCGSIRGGREDRTLYERIVSRLRRFGTVLTEHVAAAELGARGEEAAGGDRLIHEQDLEWLQQADVVVAEVTQPSLGVGYELGRAVAFNKRILCLFRPQSGRGEHPKPPSWLSMDPALSSFPGGL

Target ORF information:

RefSeq Version	NM_199184.2
Organism	Homo sapiens(human)
Definition	Homo sapiens 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 (DNPH1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_199184.2

ORF Insert Sequence:

ATGGCTGCTG CCATGGTGCC GGGGCGCAGC GAGAGCTGGG AGCGCGGGGA GCCTGGCCGC 
CCGGCCCTGT ACTTCTGCGG GAGCATTCGC GGCGGACGCG AGGACAGGAC GCTGTACGAG 
CGGATCGTGT CTCGGCTGCG GCGATTCGGG ACAGTGCTCA CCGAGCACGT GGCGGCCGCC 
GAGCTGGGCG CGCGCGGGGA AGAGGCTGCT GGGGGTGACA GGCTCATCCA TGAGCAGGAC 
CTGGAGTGGC TGCAGCAGGC GGACGTGGTC GTGGCAGAAG TGACACAGCC ATCCTTGGGT 
GTAGGCTATG AGCTGGGCCG GGCCGTGGCC TTTAACAAGC GGATCCTGTG CCTGTTCCGC 
CCGCAGTCTG GCCGCGGTGA GCACCCCAAG CCTCCCTCCT GGCTTTCTAT GGACCCAGCC 
CTCAGCTCCT TCCCTGGTGG GCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DNPH1 ( NM_006443.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_006434.1 Homo sapiens 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 (DNPH1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu13145
Clone ID Related Accession (Same CDS sequence)	NM_006443.3 , NM_006443.2
Accession Version	NM_006443.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 525bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-03
Organism	Homo sapiens(human)
Product	2'-deoxynucleoside 5'-phosphate N-hydrolase 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL133375.25, BM747628.1 and BC011683.2. On Jun 2, 2019 this sequence version replaced NM_006443.2. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EU585603.1, BC011683.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2153946 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCTGCTG CCATGGTGCC GGGGCGCAGC GAGAGCTGGG AGCGCGGGGA GCCTGGCCGC 
CCGGCCCTGT ACTTCTGCGG GAGCATTCGC GGCGGACGCG AGGACAGGAC GCTGTACGAG 
CGGATCGTGT CTCGGCTGCG GCGATTCGGG ACAGTGCTCA CCGAGCACGT GGCGGCCGCC 
GAGCTGGGCG CGCGCGGGGA AGAGGCTGCT GGGGGTGACA GGCTCATCCA TGAGCAGGAC 
CTGGAGTGGC TGCAGCAGGC GGACGTGGTC GTGGCAGAAG TGACACAGCC ATCCTTGGGT 
GTAGGCTATG AGCTGGGCCG GGCCGTGGCC TTTAACAAGC GGATCCTGTG CCTGTTCCGC 
CCGCAGTCTG GCCGCGTGCT TTCGGCCATG ATCCGGGGAG CAGCAGATGG CTCTCGGTTC 
CAGGTGTGGG ACTATGAGGA GGGAGAGGTG GAGGCCCTGC TGGATCGATA CTTCGAGGCT 
GATCCTCCAG GGCAGGTGGC TGCCTCCCCT GACCCAACCA CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006434.1
CDS	26..550
Translation	MAAAMVPGRSESWERGEPGRPALYFCGSIRGGREDRTLYERIVSRLRRFGTVLTEHVAAAELGARGEEAAGGDRLIHEQDLEWLQQADVVVAEVTQPSLGVGYELGRAVAFNKRILCLFRPQSGRVLSAMIRGAADGSRFQVWDYEEGEVEALLDRYFEADPPGQVAASPDPTT

Target ORF information:

RefSeq Version	NM_006443.3
Organism	Homo sapiens(human)
Definition	Homo sapiens 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 (DNPH1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006443.3

ORF Insert Sequence:

ATGGCTGCTG CCATGGTGCC GGGGCGCAGC GAGAGCTGGG AGCGCGGGGA GCCTGGCCGC 
CCGGCCCTGT ACTTCTGCGG GAGCATTCGC GGCGGACGCG AGGACAGGAC GCTGTACGAG 
CGGATCGTGT CTCGGCTGCG GCGATTCGGG ACAGTGCTCA CCGAGCACGT GGCGGCCGCC 
GAGCTGGGCG CGCGCGGGGA AGAGGCTGCT GGGGGTGACA GGCTCATCCA TGAGCAGGAC 
CTGGAGTGGC TGCAGCAGGC GGACGTGGTC GTGGCAGAAG TGACACAGCC ATCCTTGGGT 
GTAGGCTATG AGCTGGGCCG GGCCGTGGCC TTTAACAAGC GGATCCTGTG CCTGTTCCGC 
CCGCAGTCTG GCCGCGTGCT TTCGGCCATG ATCCGGGGAG CAGCAGATGG CTCTCGGTTC 
CAGGTGTGGG ACTATGAGGA GGGAGAGGTG GAGGCCCTGC TGGATCGATA CTTCGAGGCT 
GATCCTCCAG GGCAGGTGGC TGCCTCCCCT GACCCAACCA CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DNPH1 ( NM_006443.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_006434.1 Homo sapiens 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 (DNPH1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu13145
Clone ID Related Accession (Same CDS sequence)	NM_006443.3 , NM_006443.2
Accession Version	NM_006443.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 525bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-15
Organism	Homo sapiens(human)
Product	2'-deoxynucleoside 5'-phosphate N-hydrolase 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM747628.1 and BC011683.2. On Dec 4, 2003 this sequence version replaced NM_006443.1. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.58347.1, SRR1163655.313594.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2153946 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGCTG CCATGGTGCC GGGGCGCAGC GAGAGCTGGG AGCGCGGGGA GCCTGGCCGC 
CCGGCCCTGT ACTTCTGCGG GAGCATTCGC GGCGGACGCG AGGACAGGAC GCTGTACGAG 
CGGATCGTGT CTCGGCTGCG GCGATTCGGG ACAGTGCTCA CCGAGCACGT GGCGGCCGCC 
GAGCTGGGCG CGCGCGGGGA AGAGGCTGCT GGGGGTGACA GGCTCATCCA TGAGCAGGAC 
CTGGAGTGGC TGCAGCAGGC GGACGTGGTC GTGGCAGAAG TGACACAGCC ATCCTTGGGT 
GTAGGCTATG AGCTGGGCCG GGCCGTGGCC TTTAACAAGC GGATCCTGTG CCTGTTCCGC 
CCGCAGTCTG GCCGCGTGCT TTCGGCCATG ATCCGGGGAG CAGCAGATGG CTCTCGGTTC 
CAGGTGTGGG ACTATGAGGA GGGAGAGGTG GAGGCCCTGC TGGATCGATA CTTCGAGGCT 
GATCCTCCAG GGCAGGTGGC TGCCTCCCCT GACCCAACCA CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006434.1
CDS	18..542
Translation	MAAAMVPGRSESWERGEPGRPALYFCGSIRGGREDRTLYERIVSRLRRFGTVLTEHVAAAELGARGEEAAGGDRLIHEQDLEWLQQADVVVAEVTQPSLGVGYELGRAVAFNKRILCLFRPQSGRVLSAMIRGAADGSRFQVWDYEEGEVEALLDRYFEADPPGQVAASPDPTT

Target ORF information:

RefSeq Version	NM_006443.2
Organism	Homo sapiens(human)
Definition	Homo sapiens 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 (DNPH1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006443.2

ORF Insert Sequence:

ATGGCTGCTG CCATGGTGCC GGGGCGCAGC GAGAGCTGGG AGCGCGGGGA GCCTGGCCGC 
CCGGCCCTGT ACTTCTGCGG GAGCATTCGC GGCGGACGCG AGGACAGGAC GCTGTACGAG 
CGGATCGTGT CTCGGCTGCG GCGATTCGGG ACAGTGCTCA CCGAGCACGT GGCGGCCGCC 
GAGCTGGGCG CGCGCGGGGA AGAGGCTGCT GGGGGTGACA GGCTCATCCA TGAGCAGGAC 
CTGGAGTGGC TGCAGCAGGC GGACGTGGTC GTGGCAGAAG TGACACAGCC ATCCTTGGGT 
GTAGGCTATG AGCTGGGCCG GGCCGTGGCC TTTAACAAGC GGATCCTGTG CCTGTTCCGC 
CCGCAGTCTG GCCGCGTGCT TTCGGCCATG ATCCGGGGAG CAGCAGATGG CTCTCGGTTC 
CAGGTGTGGG ACTATGAGGA GGGAGAGGTG GAGGCCCTGC TGGATCGATA CTTCGAGGCT 
GATCCTCCAG GGCAGGTGGC TGCCTCCCCT GACCCAACCA CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

6-(Hetero)Arylpurine nucleotides as inhibitors of the oncogenic target DNPH1: synthesis, structural studies and cytotoxic activities.
European journal of medicinal chemistry85418-37(2014 Oct)
Amiable C,Paoletti J,Haouz A,Padilla A,Labesse G,Kaminski PA,Pochet S

Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects.
PloS one8(11)e79629(2013)
Deng X,Sabino EC,Cunha-Neto E,Ribeiro AL,Ianni B,Mady C,Busch MP,Seielstad M,

Analysis of proteomic changes induced upon cellular differentiation of the human intestinal cell line Caco-2.
Development, growth & differentiation53(3)411-26(2011 Apr)
Buhrke T,Lengler I,Lampen A

Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells.
Molecular & cellular proteomics : MCP10(2)M110.001628(2011 Feb)
Lee OH,Kim H,He Q,Baek HJ,Yang D,Chen LY,Liang J,Chae HK,Safari A,Liu D,Songyang Z

Probing the active site of the deoxynucleotide N-hydrolase Rcl encoded by the rat gene c6orf108.
The Journal of biological chemistry285(53)41806-14(2010 Dec)
Dupouy C,Zhang C,Padilla A,Pochet S,Kaminski PA

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DNPH1 cDNA ORF clone, Homo sapiens(human)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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