MAB21L2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MAB21L2
Entrez Gene ID	10586
Full Name	mab-21 like 2
Synonyms	MCOPS14,MCSKS14
General protein information	Preferred Names mab-21 like 2 Names protein mab-21-like 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 4 Map Location: 4q31.3
Summary	This gene is similar to the C. elegans MAB-21 cell fate-determining gene, a downstream target of transforming growth factor-beta signaling. It is thought that this gene may be involved in neural development. The protein encoded by this gene is primarily nuclear, although some cytoplasmic localization has been observed. [provided by RefSeq, Jul 2008].
Disorder MIM:	604357
Disorder Html:	Microphthalmia/coloboma and skeletal dysplasia syndrome, 615877 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_006439.4	NP_006430.1	protein mab-21-like 2
NM_006439.5	NP_006430.1	protein mab-21-like 2

Pathways from BioSystems

Homologies

	MAB21L2	XP_001082398.1
Xenopus tropicalis (tropical clawed frog)	mab21l2	NP_001096455.1
Anopheles gambiae (African malaria mosquito)	MB21L_ANOGA	XP_309230.3
Homo sapiens (human)	MAB21L2	NP_006430.1
Pan troglodytes (chimpanzee)	MAB21L2	XP_001151747.1
Bos taurus (cattle)	MAB21L2	XP_002694365.1
Mus musculus (house mouse)	Mab21l2	NP_035969.2
Canis lupus familiaris (dog)	MAB21L2	XP_867530.2
Rattus norvegicus (Norway rat)	Mab21l2	NP_001102861.1
Danio rerio (zebrafish)	mab21l2	NP_694507.1
Drosophila melanogaster (fruit fly)	CG4766	NP_572287.1

Gene Ontology
Bibliography

Related articles in PubMed

The Male Abnormal Gene Family 21 (Mab21) Members Regulate Eye Development.
Huang ZX, Xiang JW, Zhou L, Nie Q, Wang L, Chen ZG, Hu XH, Xiao Y, Qing WJ, Liu YF, Sun Q, Tang XC, Liu FY, Luo ZW, Liu WB, Li DW
Current molecular medicine16(7)660-667(2016)

A Novel Oculo-Skeletal syndrome with intellectual disability caused by a particular MAB21L2 mutation.
Horn D, Prescott T, Houge G, Br?kke K, Rosendahl K, Nishimura G, FitzPatrick DR, Spranger J
European journal of medical genetics58(8)387-91(2015 Aug)

Mutations in MAB21L2 result in ocular Coloboma, microcornea and cataracts.
Deml B, Kariminejad A, Borujerdi RH, Muheisen S, Reis LM, Semina EV
PLoS genetics11(2)e1005002(2015)

Monoallelic and biallelic mutations in MAB21L2 cause a spectrum of major eye malformations.
Rainger J, Pehlivan D, Johansson S, Bengani H, Sanchez-Pulido L, Williamson KA, Ture M, Barker H, Rosendahl K, Spranger J, Horn D, Meynert A, Floyd JA, Prescott T, Anderson CA, Rainger JK, Karaca E, Gonzaga-Jauregui C, Jhangiani S, Muzny DM, Seawright A, Soares DC, Kharbanda M, Murday V, Finch A, , , Gibbs RA, van Heyningen V, Taylor MS, Yakut T, Knappskog PM, Hurles ME, Ponting CP, Lupski JR, Houge G, FitzPatrick DR
American journal of human genetics94(6)915-23(2014 Jun)

Two murine and human homologs of mab-21, a cell fate determination gene involved in Caenorhabditis elegans neural development.
Mariani M, Baldessari D, Francisconi S, Viggiano L, Rocchi M, Zappavigna V, Malgaretti N, Consalez GG
Human molecular genetics8(13)2397-406(1999 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

mab21 gene family members, mab21l1 and mab21l2, play important roles in regulating eye development. [review]
Title: The Male Abnormal Gene Family 21 (Mab21) Members Regulate Eye Development.

The two unrelated individuals with a novel oculo-skeletal syndrome with intellectual disability described are heterozygous carriers of the same de novo missense mutation c.151C > T (p.Arg51Cys) in MAB21L2.
Title: A Novel Oculo-Skeletal syndrome with intellectual disability caused by a particular MAB21L2 mutation.

These findings support the identification of MAB21L2 as a novel factor involved in human coloboma and highlight the power of genome editing manipulation in model organisms for analysis of the effects of whole exome variation in humans.
Title: Mutations in MAB21L2 result in ocular Coloboma, microcornea and cataracts.

This report provides compelling human genomic and genetic evidence that mutations in MAB21L2 cause major eye malformations.
Title: Monoallelic and biallelic mutations in MAB21L2 cause a spectrum of major eye malformations.

The following MAB21L2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAB21L2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu31799	NM_006439.5 Latest version!	Homo sapiens mab-21 like 2 (MAB21L2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$265.30 $379.00
View Old Accession Versions >>
OHu31799	NM_006439.4	Homo sapiens mab-21 like 2 (MAB21L2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MAB21L2 ( NM_006439.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_006430.1 Homo sapiens mab-21 like 2 (MAB21L2), mRNA.

Price & Availability↑

CloneID	OHu31799
Clone ID Related Accession (Same CDS sequence)	NM_006439.4 , NM_006439.5
Accession Version	NM_006439.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1080bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-23
Organism	Homo sapiens(human)
Product	protein mab-21-like 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC110813.4 and BC009983.2. This sequence is a reference standard in the RefSeqGene project. On Aug 1, 2008 this sequence version replaced NM_006439.3. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this RefSeq transcript is supported by transcript alignments. COMPLETENESS: complete on the 3' end.

ATGATCGCCG CTCAGGCCAA GCTGGTTTAC CAGCTCAATA AGTACTACAC TGAGCGCTGT 
CAGGCGCGCA AGGCGGCCAT CGCCAAAACC ATCCGAGAGG TCTGTAAGGT GGTCTCGGAC 
GTGCTCAAGG AAGTGGAGGT GCAGGAGCCT CGCTTCATCA GCTCCTTGAG CGAGATCGAT 
GCCCGCTACG AGGGGCTCGA GGTCATTTCG CCCACCGAAT TTGAGGTGGT GCTCTACCTA 
AACCAGATGG GCGTCTTCAA CTTCGTGGAC GACGGCTCGC TGCCCGGCTG CGCAGTGCTC 
AAACTGAGCG ATGGGCGGAA GCGGAGCATG TCTCTCTGGG TCGAGTTCAT CACGGCGTCG 
GGCTATCTCT CAGCGCGTAA GATCCGCTCG CGTTTCCAGA CGCTGGTGGC CCAGGCGGTG 
GACAAGTGCA GCTATCGGGA TGTGGTCAAG ATGATCGCGG ACACCAGCGA GGTCAAGTTG 
CGCATCAGGG AGCGCTATGT GGTGCAAATC ACTCCGGCGT TCAAGTGCAC CGGGATCTGG 
CCTCGCAGCG CGGCACAGTG GCCTATGCCC CACATCCCTT GGCCCGGCCC CAATCGGGTG 
GCCGAGGTCA AGGCCGAAGG GTTCAACTTG CTCTCGAAGG AGTGCTACTC GCTGACCGGC 
AAGCAGAGCT CGGCAGAGAG CGACGCCTGG GTGCTACAGT TCGGGGAGGC GGAGAACCGC 
CTGCTGATGG GCGGCTGCCG AAACAAGTGC CTCTCAGTGC TGAAGACTCT GCGGGACCGC 
CACCTGGAGC TACCCGGCCA GCCGCTCAAC AACTACCACA TGAAGACGCT GCTGCTGTAC 
GAGTGCGAGA AACACCCACG AGAAACGGAC TGGGACGAGT CGTGCCTGGG CGACCGGCTC 
AACGGCATCC TGCTGCAGCT CATCTCCTGC CTGCAGTGCC GCCGCTGCCC TCACTACTTT 
CTGCCCAACC TCGACCTCTT TCAGGGCAAG CCCCATTCGG CCCTGGAGAG CGCTGCCAAG 
CAGACCTGGA GGTTGGCCAG GGAAATTCTC ACCAATCCCA AAAGCCTGGA CAAACTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006430.1
CDS	1106..2185
Translation	MIAAQAKLVYQLNKYYTERCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLSEIDARYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMIADTSEVKLRIRERYVVQITPAFKCTGIWPRSAAQWPMPHIPWPGPNRVAEVKAEGFNLLSKECYSLTGKQSSAESDAWVLQFGEAENRLLMGGCRNKCLSVLKTLRDRHLELPGQPLNNYHMKTLLLYECEKHPRETDWDESCLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALESAAKQTWRLAREILTNPKSLDKL

Target ORF information:

RefSeq Version	NM_006439.4
Organism	Homo sapiens(human)
Definition	Homo sapiens mab-21 like 2 (MAB21L2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006439.4

ORF Insert Sequence:

ATGATCGCCG CTCAGGCCAA GCTGGTTTAC CAGCTCAATA AGTACTACAC TGAGCGCTGT 
CAGGCGCGCA AGGCGGCCAT CGCCAAAACC ATCCGAGAGG TCTGTAAGGT GGTCTCGGAC 
GTGCTCAAGG AAGTGGAGGT GCAGGAGCCT CGCTTCATCA GCTCCTTGAG CGAGATCGAT 
GCCCGCTACG AGGGGCTCGA GGTCATTTCG CCCACCGAAT TTGAGGTGGT GCTCTACCTA 
AACCAGATGG GCGTCTTCAA CTTCGTGGAC GACGGCTCGC TGCCCGGCTG CGCAGTGCTC 
AAACTGAGCG ATGGGCGGAA GCGGAGCATG TCTCTCTGGG TCGAGTTCAT CACGGCGTCG 
GGCTATCTCT CAGCGCGTAA GATCCGCTCG CGTTTCCAGA CGCTGGTGGC CCAGGCGGTG 
GACAAGTGCA GCTATCGGGA TGTGGTCAAG ATGATCGCGG ACACCAGCGA GGTCAAGTTG 
CGCATCAGGG AGCGCTATGT GGTGCAAATC ACTCCGGCGT TCAAGTGCAC CGGGATCTGG 
CCTCGCAGCG CGGCACAGTG GCCTATGCCC CACATCCCTT GGCCCGGCCC CAATCGGGTG 
GCCGAGGTCA AGGCCGAAGG GTTCAACTTG CTCTCGAAGG AGTGCTACTC GCTGACCGGC 
AAGCAGAGCT CGGCAGAGAG CGACGCCTGG GTGCTACAGT TCGGGGAGGC GGAGAACCGC 
CTGCTGATGG GCGGCTGCCG AAACAAGTGC CTCTCAGTGC TGAAGACTCT GCGGGACCGC 
CACCTGGAGC TACCCGGCCA GCCGCTCAAC AACTACCACA TGAAGACGCT GCTGCTGTAC 
GAGTGCGAGA AACACCCACG AGAAACGGAC TGGGACGAGT CGTGCCTGGG CGACCGGCTC 
AACGGCATCC TGCTGCAGCT CATCTCCTGC CTGCAGTGCC GCCGCTGCCC TCACTACTTT 
CTGCCCAACC TCGACCTCTT TCAGGGCAAG CCCCATTCGG CCCTGGAGAG CGCTGCCAAG 
CAGACCTGGA GGTTGGCCAG GGAAATTCTC ACCAATCCCA AAAGCCTGGA CAAACTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAB21L2 ( NM_006439.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_006430.1 Homo sapiens mab-21 like 2 (MAB21L2), mRNA.

Price & Availability↑

CloneID	OHu31799
Clone ID Related Accession (Same CDS sequence)	NM_006439.4 , NM_006439.5
Accession Version	NM_006439.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1080bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-24
Organism	Homo sapiens(human)
Product	protein mab-21-like 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC110813.4 and BC009983.2. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_006439.4. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this RefSeq transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript is intronless :: AK055665.1, AF262032.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000317605.6/ ENSP00000324701.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGATCGCCG CTCAGGCCAA GCTGGTTTAC CAGCTCAATA AGTACTACAC TGAGCGCTGT 
CAGGCGCGCA AGGCGGCCAT CGCCAAAACC ATCCGAGAGG TCTGTAAGGT GGTCTCGGAC 
GTGCTCAAGG AAGTGGAGGT GCAGGAGCCT CGCTTCATCA GCTCCTTGAG CGAGATCGAT 
GCCCGCTACG AGGGGCTCGA GGTCATTTCG CCCACCGAAT TTGAGGTGGT GCTCTACCTA 
AACCAGATGG GCGTCTTCAA CTTCGTGGAC GACGGCTCGC TGCCCGGCTG CGCAGTGCTC 
AAACTGAGCG ATGGGCGGAA GCGGAGCATG TCTCTCTGGG TCGAGTTCAT CACGGCGTCG 
GGCTATCTCT CAGCGCGTAA GATCCGCTCG CGTTTCCAGA CGCTGGTGGC CCAGGCGGTG 
GACAAGTGCA GCTATCGGGA TGTGGTCAAG ATGATCGCGG ACACCAGCGA GGTCAAGTTG 
CGCATCAGGG AGCGCTATGT GGTGCAAATC ACTCCGGCGT TCAAGTGCAC CGGGATCTGG 
CCTCGCAGCG CGGCACAGTG GCCTATGCCC CACATCCCTT GGCCCGGCCC CAATCGGGTG 
GCCGAGGTCA AGGCCGAAGG GTTCAACTTG CTCTCGAAGG AGTGCTACTC GCTGACCGGC 
AAGCAGAGCT CGGCAGAGAG CGACGCCTGG GTGCTACAGT TCGGGGAGGC GGAGAACCGC 
CTGCTGATGG GCGGCTGCCG AAACAAGTGC CTCTCAGTGC TGAAGACTCT GCGGGACCGC 
CACCTGGAGC TACCCGGCCA GCCGCTCAAC AACTACCACA TGAAGACGCT GCTGCTGTAC 
GAGTGCGAGA AACACCCACG AGAAACGGAC TGGGACGAGT CGTGCCTGGG CGACCGGCTC 
AACGGCATCC TGCTGCAGCT CATCTCCTGC CTGCAGTGCC GCCGCTGCCC TCACTACTTT 
CTGCCCAACC TCGACCTCTT TCAGGGCAAG CCCCATTCGG CCCTGGAGAG CGCTGCCAAG 
CAGACCTGGA GGTTGGCCAG GGAAATTCTC ACCAATCCCA AAAGCCTGGA CAAACTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006430.1
CDS	880..1959
Translation	MIAAQAKLVYQLNKYYTERCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLSEIDARYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMIADTSEVKLRIRERYVVQITPAFKCTGIWPRSAAQWPMPHIPWPGPNRVAEVKAEGFNLLSKECYSLTGKQSSAESDAWVLQFGEAENRLLMGGCRNKCLSVLKTLRDRHLELPGQPLNNYHMKTLLLYECEKHPRETDWDESCLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALESAAKQTWRLAREILTNPKSLDKL

Target ORF information:

RefSeq Version	NM_006439.5
Organism	Homo sapiens(human)
Definition	Homo sapiens mab-21 like 2 (MAB21L2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006439.5

ORF Insert Sequence:

ATGATCGCCG CTCAGGCCAA GCTGGTTTAC CAGCTCAATA AGTACTACAC TGAGCGCTGT 
CAGGCGCGCA AGGCGGCCAT CGCCAAAACC ATCCGAGAGG TCTGTAAGGT GGTCTCGGAC 
GTGCTCAAGG AAGTGGAGGT GCAGGAGCCT CGCTTCATCA GCTCCTTGAG CGAGATCGAT 
GCCCGCTACG AGGGGCTCGA GGTCATTTCG CCCACCGAAT TTGAGGTGGT GCTCTACCTA 
AACCAGATGG GCGTCTTCAA CTTCGTGGAC GACGGCTCGC TGCCCGGCTG CGCAGTGCTC 
AAACTGAGCG ATGGGCGGAA GCGGAGCATG TCTCTCTGGG TCGAGTTCAT CACGGCGTCG 
GGCTATCTCT CAGCGCGTAA GATCCGCTCG CGTTTCCAGA CGCTGGTGGC CCAGGCGGTG 
GACAAGTGCA GCTATCGGGA TGTGGTCAAG ATGATCGCGG ACACCAGCGA GGTCAAGTTG 
CGCATCAGGG AGCGCTATGT GGTGCAAATC ACTCCGGCGT TCAAGTGCAC CGGGATCTGG 
CCTCGCAGCG CGGCACAGTG GCCTATGCCC CACATCCCTT GGCCCGGCCC CAATCGGGTG 
GCCGAGGTCA AGGCCGAAGG GTTCAACTTG CTCTCGAAGG AGTGCTACTC GCTGACCGGC 
AAGCAGAGCT CGGCAGAGAG CGACGCCTGG GTGCTACAGT TCGGGGAGGC GGAGAACCGC 
CTGCTGATGG GCGGCTGCCG AAACAAGTGC CTCTCAGTGC TGAAGACTCT GCGGGACCGC 
CACCTGGAGC TACCCGGCCA GCCGCTCAAC AACTACCACA TGAAGACGCT GCTGCTGTAC 
GAGTGCGAGA AACACCCACG AGAAACGGAC TGGGACGAGT CGTGCCTGGG CGACCGGCTC 
AACGGCATCC TGCTGCAGCT CATCTCCTGC CTGCAGTGCC GCCGCTGCCC TCACTACTTT 
CTGCCCAACC TCGACCTCTT TCAGGGCAAG CCCCATTCGG CCCTGGAGAG CGCTGCCAAG 
CAGACCTGGA GGTTGGCCAG GGAAATTCTC ACCAATCCCA AAAGCCTGGA CAAACTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The Male Abnormal Gene Family 21 (Mab21) Members Regulate Eye Development.
Current molecular medicine16(7)660-667(2016)
Huang ZX,Xiang JW,Zhou L,Nie Q,Wang L,Chen ZG,Hu XH,Xiao Y,Qing WJ,Liu YF,Sun Q,Tang XC,Liu FY,Luo ZW,Liu WB,Li DW

A Novel Oculo-Skeletal syndrome with intellectual disability caused by a particular MAB21L2 mutation.
European journal of medical genetics58(8)387-91(2015 Aug)
Horn D,Prescott T,Houge G,Br?kke K,Rosendahl K,Nishimura G,FitzPatrick DR,Spranger J

Mutations in MAB21L2 result in ocular Coloboma, microcornea and cataracts.
PLoS genetics11(2)e1005002(2015)
Deml B,Kariminejad A,Borujerdi RH,Muheisen S,Reis LM,Semina EV

Monoallelic and biallelic mutations in MAB21L2 cause a spectrum of major eye malformations.
American journal of human genetics94(6)915-23(2014 Jun)
Rainger J,Pehlivan D,Johansson S,Bengani H,Sanchez-Pulido L,Williamson KA,Ture M,Barker H,Rosendahl K,Spranger J,Horn D,Meynert A,Floyd JA,Prescott T,Anderson CA,Rainger JK,Karaca E,Gonzaga-Jauregui C,Jhangiani S,Muzny DM,Seawright A,Soares DC,Kharbanda M,Murday V,Finch A,,,Gibbs RA,van Heyningen V,Taylor MS,Yakut T,Knappskog PM,Hurles ME,Ponting CP,Lupski JR,Houge G,FitzPatrick DR

Two murine and human homologs of mab-21, a cell fate determination gene involved in Caenorhabditis elegans neural development.
Human molecular genetics8(13)2397-406(1999 Dec)
Mariani M,Baldessari D,Francisconi S,Viggiano L,Rocchi M,Zappavigna V,Malgaretti N,Consalez GG

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MAB21L2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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