CEL cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CEL
Entrez Gene ID	1056
Full Name	carboxyl ester lipase
Synonyms	BAL,BSDL,BSSL,CELL,CEase,FAP,FAPP,LIPA,MODY8
General protein information	Preferred Names carboxyl ester lipase Names bile salt-activated lipase bile salt-dependent lipase, oncofetal isoform bucelipase carboxyl ester hydrolase carboxyl ester lipase (bile salt-stimulated lipase) cholesterol esterase fetoacinar pancreatic protein lysophospholipase, pancreatic sterol esterase
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 9 Map Location: 9q34.13
Summary	The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat (VNTR) polymorphism in the coding region that may influence the function of the encoded protein. [provided by RefSeq, Jul 2008].
Disorder MIM:	114840
Disorder Html:	Maturity-onset diabetes of the young, type VIII, 609812 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001807.6	NP_001798.3	bile salt-activated lipase precursor
NM_001807.4	NP_001798.2	bile salt-activated lipase precursor
NM_001807.5	NP_001798.3	bile salt-activated lipase precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CEL	XP_003951607.1
Gallus gallus (chicken)	CEL	NP_001013015.1
	CEL	XP_001118455.2
Mus musculus (house mouse)	Cel	NP_034015.1
Danio rerio (zebrafish)	cel.2	XP_005161146.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001722	XP_321363.4
Xenopus tropicalis (tropical clawed frog)	LOC100492444	XP_002936238.2
Bos taurus (cattle)	CEL	NP_001013601.1
Homo sapiens (human)	CEL	NP_001798.2
Canis lupus familiaris (dog)	CEL	XP_548401.1
Rattus norvegicus (Norway rat)	Cel	NP_058693.2
Danio rerio (zebrafish)	cel.1	NP_955901.1
Anopheles gambiae (African malaria mosquito)	COEAE1A	XP_321362.2
Anopheles gambiae (African malaria mosquito)	COEAE6O	XP_312052.3
Xenopus tropicalis (tropical clawed frog)	cel	NP_001120027.1

Gene Ontology
Bibliography

Related articles in PubMed

Copy number variants and VNTR length polymorphisms of the carboxyl-ester lipase (CEL) gene as risk factors in pancreatic cancer.
Dalva M, El Jellas K, Steine SJ, Johansson BB, Ringdal M, Torsvik J, Immervoll H, Hoem D, Laemmerhirt F, Simon P, Lerch MM, Johansson S, Nj?lstad PR, Weiss FU, Fjeld K, Molven A
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]17(1)83-88(2017 Jan - Feb)

Length of Variable Numbers of Tandem Repeats in the Carboxyl Ester Lipase (CEL) Gene May Confer Susceptibility to Alcoholic Liver Cirrhosis but Not Alcoholic Chronic Pancreatitis.
Fjeld K, Beer S, Johnstone M, Zimmer C, M?ssner J, Ruffert C, Krehan M, Zapf C, Nj?lstad PR, Johansson S, Bugert P, Miyajima F, Liloglou T, Brown LJ, Winn SA, Davies K, Latawiec D, Gunson BK, Criddle DN, Pirmohamed M, Gr?tzmann R, Michl P, Greenhalf W, Molven A, Sutton R, Rosendahl J
PloS one11(11)e0165567(2016)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

We could not demonstrate an association between CEL copy number variants and pancreatic cancer. An association is also unlikely for CEL variable number of tandem repeat lengths (VNTR), although analyses in larger materials are necessary to completely exclude an effect of rare VNTR alleles.
Title: Copy number variants and VNTR length polymorphisms of the carboxyl-ester lipase (CEL) gene as risk factors in pancreatic cancer.

CEL deletion mutation increased endoplasmic reticulum stress, activated the unfolded protein response, and caused cell death by apoptosis in chronic pancreatitis.
Title: A Carboxyl Ester Lipase (CEL) Mutant Causes Chronic Pancreatitis by Forming Intracellular Aggregates That Activate Apoptosis.

The CEL gene harbours a variable number of tandem repeats (VNTR) region in exon 11. These results suggest that CEL VNTR lengths might associate with Alcoholic Liver Cirrhosis.
Title: Length of Variable Numbers of Tandem Repeats in the Carboxyl Ester Lipase (CEL) Gene May Confer Susceptibility to Alcoholic Liver Cirrhosis but Not Alcoholic Chronic Pancreatitis.

Data show that the c.1719C > T transition (single nucleotide polymorphism rs488087) present in bile salt-dependent lipase (BSDL) VNTR may be a useful marker for defining a population at risk of developing pancreatic cancer (PC)
Title: Rs488087 single nucleotide polymorphism as predictive risk factor for pancreatic cancers.

Expression of CEL-HYB in originating from a crossover between CEL and its neighboring pseudogene, CELP is associated with chronic pancreatitis.
Title: A recombined allele of the lipase gene CEL and its pseudogene CELP confers susceptibility to chronic pancreatitis.

The following CEL gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CEL cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu107896	NM_001807.6 Latest version!	Homo sapiens carboxyl ester lipase (CEL), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OHu22073	NM_001807.4 Latest version!	Homo sapiens carboxyl ester lipase (CEL), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
View Old Accession Versions >>
OHu107896	NM_001807.5	Homo sapiens carboxyl ester lipase (CEL), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CEL ( NM_001807.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_001798.3 Homo sapiens carboxyl ester lipase (CEL), mRNA.

Price & Availability↑

CloneID	OHu107896
Clone ID Related Accession (Same CDS sequence)	NM_001807.6 , NM_001807.5
Accession Version	NM_001807.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2262bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-19
Organism	Homo sapiens(human)
Product	bile salt-activated lipase precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL162417.23. On Nov 21, 2019 this sequence version replaced NM_001807.5. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGGCGCC TGCAACTGGT TGTGTTGGGC CTCACCTGCT GCTGGGCAGT GGCGAGTGCC 
GCGAAGCTGG GCGCCGTGTA CACAGAAGGT GGGTTCGTGG AAGGCGTCAA TAAGAAGCTC 
GGCCTCCTGG GTGACTCTGT GGACATCTTC AAGGGCATCC CCTTCGCAGC TCCCACCAAG 
GCCCTGGAAA ATCCTCAGCC ACATCCTGGC TGGCAAGGGA CCCTGAAGGC CAAGAACTTC 
AAGAAGAGAT GCCTGCAGGC CACCATCACC CAGGACAGCA CCTACGGGGA TGAAGACTGC 
CTGTACCTCA ACATTTGGGT GCCCCAGGGC AGGAAGCAAG TCTCCCGGGA CCTGCCCGTT 
ATGATCTGGA TCTATGGAGG CGCCTTCCTC ATGGGGTCCG GCCATGGGGC CAACTTCCTC 
AACAACTACC TGTATGACGG CGAGGAGATC GCCACACGCG GAAACGTCAT CGTGGTCACC 
TTCAACTACC GTGTCGGCCC CCTTGGGTTC CTCAGCACTG GGGACGCCAA TCTGCCAGGT 
AACTATGGCC TTCGGGATCA GCACATGGCC ATTGCTTGGG TGAAGAGGAA TATCGCGGCC 
TTCGGGGGGG ACCCCAACAA CATCACGCTC TTCGGGGAGT CTGCTGGAGG TGCCAGCGTC 
TCTCTGCAGA CCCTCTCCCC CTACAACAAG GGCCTCATCC GGCGAGCCAT CAGCCAGAGC 
GGCGTGGCCC TGAGTCCCTG GGTCATCCAG AAAAACCCAC TCTTCTGGGC CAAAAAGGTG 
GCTGAGAAGG TGGGTTGCCC TGTGGGTGAT GCCGCCAGGA TGGCCCAGTG TCTGAAGGTT 
ACTGATCCCC GAGCCCTGAC GCTGGCCTAT AAGGTGCCGC TGGCAGGCCT GGAGTACCCC 
ATGCTGCACT ATGTGGGCTT CGTCCCTGTC ATTGATGGAG ACTTCATCCC CGCTGACCCG 
ATCAACCTGT ACGCCAACGC CGCCGACATC GACTATATAG CAGGCACCAA CAACATGGAC 
GGCCACATCT TCGCCAGCAT CGACATGCCT GCCATCAACA AGGGCAACAA GAAAGTCACG 
GAGGAGGACT TCTACAAGCT GGTCAGTGAG TTCACAATCA CCAAGGGGCT CAGAGGCGCC 
AAGACGACCT TTGATGTCTA CACCGAGTCC TGGGCCCAGG ACCCATCCCA GGAGAATAAG 
AAGAAGACTG TGGTGGACTT TGAGACCGAT GTCCTCTTCC TGGTGCCCAC CGAGATTGCC 
CTAGCCCAGC ACAGAGCCAA TGCCAAGAGT GCCAAGACCT ACGCCTACCT GTTTTCCCAT 
CCCTCTCGGA TGCCCGTCTA CCCCAAATGG GTGGGGGCCG ACCATGCAGA TGACATTCAG 
TACGTTTTCG GGAAGCCCTT CGCCACCCCC ACGGGCTACC GGCCCCAAGA CAGGACAGTC 
TCTAAGGCCA TGATCGCCTA CTGGACCAAC TTTGCCAAAA CAGGGGACCC CAACATGGGC 
GACTCGGCTG TGCCCACACA CTGGGAACCC TACACTACGG AAAACAGCGG CTACCTGGAG 
ATCACCAAGA AGATGGGCAG CAGCTCCATG AAGCGGAGCC TGAGAACCAA CTTCCTGCGC 
TACTGGACCC TCACCTATCT GGCGCTGCCC ACAGTGACCG ACCAGGAGGC CACCCCTGTG 
CCCCCCACAG GGGACTCCGA GGCCACTCCC GTGCCCCCCA CGGGTGACTC CGAGACCGCC 
CCCGTGCCGC CCACGGGTGA CTCCGGGGCC CCCCCCGTGC CGCCCACGGG TGACTCCGGG 
GCCCCCCCCG TGCCGCCCAC GGGTGACTCC GGGGCCCCCC CCGTGCCGCC CACGGGTGAC 
TCCGGGGCCC CCCCCGTGCC GCCCACGGGT GACTCCGGGG CCCCCCCCGT GCCGCCCACG 
GGTGACTCCG GGGCCCCCCC CGTGCCGCCC ACGGGTGACT CCGGGGCCCC CCCCGTGCCG 
CCCACGGGTG ACTCCGGCGC CCCCCCCGTG CCGCCCACGG GTGACGCCGG GCCCCCCCCC 
GTGCCGCCCA CGGGTGACTC CGGCGCCCCC CCCGTGCCGC CCACGGGTGA CTCCGGGGCC 
CCCCCCGTGA CCCCCACGGG TGACTCCGAG ACCGCCCCCG TGCCGCCCAC GGGTGACTCC 
GGGGCCCCCC CTGTGCCCCC CACGGGTGAC TCTGAGGCTG CCCCTGTGCC CCCCACAGAT 
GACTCCAAGG AAGCTCAGAT GCCTGCAGTC ATTAGGTTTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001798.3
CDS	23..2284
Translation	MGRLQLVVLGLTCCWAVASAAKLGAVYTEGGFVEGVNKKLGLLGDSVDIFKGIPFAAPTKALENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPRALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYANAADIDYIAGTNNMDGHIFASIDMPAINKGNKKVTEEDFYKLVSEFTITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPSRMPVYPKWVGADHADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKMGSSSMKRSLRTNFLRYWTLTYLALPTVTDQEATPVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPPTDDSKEAQMPAVIRF

Target ORF information:

RefSeq Version	NM_001807.6
Organism	Homo sapiens(human)
Definition	Homo sapiens carboxyl ester lipase (CEL), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001807.6

ORF Insert Sequence:

ATGGGGCGCC TGCAACTGGT TGTGTTGGGC CTCACCTGCT GCTGGGCAGT GGCGAGTGCC 
GCGAAGCTGG GCGCCGTGTA CACAGAAGGT GGGTTCGTGG AAGGCGTCAA TAAGAAGCTC 
GGCCTCCTGG GTGACTCTGT GGACATCTTC AAGGGCATCC CCTTCGCAGC TCCCACCAAG 
GCCCTGGAAA ATCCTCAGCC ACATCCTGGC TGGCAAGGGA CCCTGAAGGC CAAGAACTTC 
AAGAAGAGAT GCCTGCAGGC CACCATCACC CAGGACAGCA CCTACGGGGA TGAAGACTGC 
CTGTACCTCA ACATTTGGGT GCCCCAGGGC AGGAAGCAAG TCTCCCGGGA CCTGCCCGTT 
ATGATCTGGA TCTATGGAGG CGCCTTCCTC ATGGGGTCCG GCCATGGGGC CAACTTCCTC 
AACAACTACC TGTATGACGG CGAGGAGATC GCCACACGCG GAAACGTCAT CGTGGTCACC 
TTCAACTACC GTGTCGGCCC CCTTGGGTTC CTCAGCACTG GGGACGCCAA TCTGCCAGGT 
AACTATGGCC TTCGGGATCA GCACATGGCC ATTGCTTGGG TGAAGAGGAA TATCGCGGCC 
TTCGGGGGGG ACCCCAACAA CATCACGCTC TTCGGGGAGT CTGCTGGAGG TGCCAGCGTC 
TCTCTGCAGA CCCTCTCCCC CTACAACAAG GGCCTCATCC GGCGAGCCAT CAGCCAGAGC 
GGCGTGGCCC TGAGTCCCTG GGTCATCCAG AAAAACCCAC TCTTCTGGGC CAAAAAGGTG 
GCTGAGAAGG TGGGTTGCCC TGTGGGTGAT GCCGCCAGGA TGGCCCAGTG TCTGAAGGTT 
ACTGATCCCC GAGCCCTGAC GCTGGCCTAT AAGGTGCCGC TGGCAGGCCT GGAGTACCCC 
ATGCTGCACT ATGTGGGCTT CGTCCCTGTC ATTGATGGAG ACTTCATCCC CGCTGACCCG 
ATCAACCTGT ACGCCAACGC CGCCGACATC GACTATATAG CAGGCACCAA CAACATGGAC 
GGCCACATCT TCGCCAGCAT CGACATGCCT GCCATCAACA AGGGCAACAA GAAAGTCACG 
GAGGAGGACT TCTACAAGCT GGTCAGTGAG TTCACAATCA CCAAGGGGCT CAGAGGCGCC 
AAGACGACCT TTGATGTCTA CACCGAGTCC TGGGCCCAGG ACCCATCCCA GGAGAATAAG 
AAGAAGACTG TGGTGGACTT TGAGACCGAT GTCCTCTTCC TGGTGCCCAC CGAGATTGCC 
CTAGCCCAGC ACAGAGCCAA TGCCAAGAGT GCCAAGACCT ACGCCTACCT GTTTTCCCAT 
CCCTCTCGGA TGCCCGTCTA CCCCAAATGG GTGGGGGCCG ACCATGCAGA TGACATTCAG 
TACGTTTTCG GGAAGCCCTT CGCCACCCCC ACGGGCTACC GGCCCCAAGA CAGGACAGTC 
TCTAAGGCCA TGATCGCCTA CTGGACCAAC TTTGCCAAAA CAGGGGACCC CAACATGGGC 
GACTCGGCTG TGCCCACACA CTGGGAACCC TACACTACGG AAAACAGCGG CTACCTGGAG 
ATCACCAAGA AGATGGGCAG CAGCTCCATG AAGCGGAGCC TGAGAACCAA CTTCCTGCGC 
TACTGGACCC TCACCTATCT GGCGCTGCCC ACAGTGACCG ACCAGGAGGC CACCCCTGTG 
CCCCCCACAG GGGACTCCGA GGCCACTCCC GTGCCCCCCA CGGGTGACTC CGAGACCGCC 
CCCGTGCCGC CCACGGGTGA CTCCGGGGCC CCCCCCGTGC CGCCCACGGG TGACTCCGGG 
GCCCCCCCCG TGCCGCCCAC GGGTGACTCC GGGGCCCCCC CCGTGCCGCC CACGGGTGAC 
TCCGGGGCCC CCCCCGTGCC GCCCACGGGT GACTCCGGGG CCCCCCCCGT GCCGCCCACG 
GGTGACTCCG GGGCCCCCCC CGTGCCGCCC ACGGGTGACT CCGGGGCCCC CCCCGTGCCG 
CCCACGGGTG ACTCCGGCGC CCCCCCCGTG CCGCCCACGG GTGACGCCGG GCCCCCCCCC 
GTGCCGCCCA CGGGTGACTC CGGCGCCCCC CCCGTGCCGC CCACGGGTGA CTCCGGGGCC 
CCCCCCGTGA CCCCCACGGG TGACTCCGAG ACCGCCCCCG TGCCGCCCAC GGGTGACTCC 
GGGGCCCCCC CTGTGCCCCC CACGGGTGAC TCTGAGGCTG CCCCTGTGCC CCCCACAGAT 
GACTCCAAGG AAGCTCAGAT GCCTGCAGTC ATTAGGTTTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CEL ( NM_001807.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_001798.3 Homo sapiens carboxyl ester lipase (CEL), mRNA.

Price & Availability↑

CloneID	OHu107896
Clone ID Related Accession (Same CDS sequence)	NM_001807.6 , NM_001807.5
Accession Version	NM_001807.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2262bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-06
Organism	Homo sapiens(human)
Product	bile salt-activated lipase precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL162417.23, BC042510.1, AF081673.1 and AK299965.1. On Jan 4, 2019 this sequence version replaced NM_001807.4. Sequence Note: The 3' terminal exon of this RefSeq is inferred based on aligning transcripts. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGGCGCC TGCAACTGGT TGTGTTGGGC CTCACCTGCT GCTGGGCAGT GGCGAGTGCC 
GCGAAGCTGG GCGCCGTGTA CACAGAAGGT GGGTTCGTGG AAGGCGTCAA TAAGAAGCTC 
GGCCTCCTGG GTGACTCTGT GGACATCTTC AAGGGCATCC CCTTCGCAGC TCCCACCAAG 
GCCCTGGAAA ATCCTCAGCC ACATCCTGGC TGGCAAGGGA CCCTGAAGGC CAAGAACTTC 
AAGAAGAGAT GCCTGCAGGC CACCATCACC CAGGACAGCA CCTACGGGGA TGAAGACTGC 
CTGTACCTCA ACATTTGGGT GCCCCAGGGC AGGAAGCAAG TCTCCCGGGA CCTGCCCGTT 
ATGATCTGGA TCTATGGAGG CGCCTTCCTC ATGGGGTCCG GCCATGGGGC CAACTTCCTC 
AACAACTACC TGTATGACGG CGAGGAGATC GCCACACGCG GAAACGTCAT CGTGGTCACC 
TTCAACTACC GTGTCGGCCC CCTTGGGTTC CTCAGCACTG GGGACGCCAA TCTGCCAGGT 
AACTATGGCC TTCGGGATCA GCACATGGCC ATTGCTTGGG TGAAGAGGAA TATCGCGGCC 
TTCGGGGGGG ACCCCAACAA CATCACGCTC TTCGGGGAGT CTGCTGGAGG TGCCAGCGTC 
TCTCTGCAGA CCCTCTCCCC CTACAACAAG GGCCTCATCC GGCGAGCCAT CAGCCAGAGC 
GGCGTGGCCC TGAGTCCCTG GGTCATCCAG AAAAACCCAC TCTTCTGGGC CAAAAAGGTG 
GCTGAGAAGG TGGGTTGCCC TGTGGGTGAT GCCGCCAGGA TGGCCCAGTG TCTGAAGGTT 
ACTGATCCCC GAGCCCTGAC GCTGGCCTAT AAGGTGCCGC TGGCAGGCCT GGAGTACCCC 
ATGCTGCACT ATGTGGGCTT CGTCCCTGTC ATTGATGGAG ACTTCATCCC CGCTGACCCG 
ATCAACCTGT ACGCCAACGC CGCCGACATC GACTATATAG CAGGCACCAA CAACATGGAC 
GGCCACATCT TCGCCAGCAT CGACATGCCT GCCATCAACA AGGGCAACAA GAAAGTCACG 
GAGGAGGACT TCTACAAGCT GGTCAGTGAG TTCACAATCA CCAAGGGGCT CAGAGGCGCC 
AAGACGACCT TTGATGTCTA CACCGAGTCC TGGGCCCAGG ACCCATCCCA GGAGAATAAG 
AAGAAGACTG TGGTGGACTT TGAGACCGAT GTCCTCTTCC TGGTGCCCAC CGAGATTGCC 
CTAGCCCAGC ACAGAGCCAA TGCCAAGAGT GCCAAGACCT ACGCCTACCT GTTTTCCCAT 
CCCTCTCGGA TGCCCGTCTA CCCCAAATGG GTGGGGGCCG ACCATGCAGA TGACATTCAG 
TACGTTTTCG GGAAGCCCTT CGCCACCCCC ACGGGCTACC GGCCCCAAGA CAGGACAGTC 
TCTAAGGCCA TGATCGCCTA CTGGACCAAC TTTGCCAAAA CAGGGGACCC CAACATGGGC 
GACTCGGCTG TGCCCACACA CTGGGAACCC TACACTACGG AAAACAGCGG CTACCTGGAG 
ATCACCAAGA AGATGGGCAG CAGCTCCATG AAGCGGAGCC TGAGAACCAA CTTCCTGCGC 
TACTGGACCC TCACCTATCT GGCGCTGCCC ACAGTGACCG ACCAGGAGGC CACCCCTGTG 
CCCCCCACAG GGGACTCCGA GGCCACTCCC GTGCCCCCCA CGGGTGACTC CGAGACCGCC 
CCCGTGCCGC CCACGGGTGA CTCCGGGGCC CCCCCCGTGC CGCCCACGGG TGACTCCGGG 
GCCCCCCCCG TGCCGCCCAC GGGTGACTCC GGGGCCCCCC CCGTGCCGCC CACGGGTGAC 
TCCGGGGCCC CCCCCGTGCC GCCCACGGGT GACTCCGGGG CCCCCCCCGT GCCGCCCACG 
GGTGACTCCG GGGCCCCCCC CGTGCCGCCC ACGGGTGACT CCGGGGCCCC CCCCGTGCCG 
CCCACGGGTG ACTCCGGCGC CCCCCCCGTG CCGCCCACGG GTGACGCCGG GCCCCCCCCC 
GTGCCGCCCA CGGGTGACTC CGGCGCCCCC CCCGTGCCGC CCACGGGTGA CTCCGGGGCC 
CCCCCCGTGA CCCCCACGGG TGACTCCGAG ACCGCCCCCG TGCCGCCCAC GGGTGACTCC 
GGGGCCCCCC CTGTGCCCCC CACGGGTGAC TCTGAGGCTG CCCCTGTGCC CCCCACAGAT 
GACTCCAAGG AAGCTCAGAT GCCTGCAGTC ATTAGGTTTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001798.3
CDS	22..2283
Translation	MGRLQLVVLGLTCCWAVASAAKLGAVYTEGGFVEGVNKKLGLLGDSVDIFKGIPFAAPTKALENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPRALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYANAADIDYIAGTNNMDGHIFASIDMPAINKGNKKVTEEDFYKLVSEFTITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPSRMPVYPKWVGADHADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKMGSSSMKRSLRTNFLRYWTLTYLALPTVTDQEATPVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPPTDDSKEAQMPAVIRF

Target ORF information:

RefSeq Version	NM_001807.5
Organism	Homo sapiens(human)
Definition	Homo sapiens carboxyl ester lipase (CEL), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001807.5

ORF Insert Sequence:

ATGGGGCGCC TGCAACTGGT TGTGTTGGGC CTCACCTGCT GCTGGGCAGT GGCGAGTGCC 
GCGAAGCTGG GCGCCGTGTA CACAGAAGGT GGGTTCGTGG AAGGCGTCAA TAAGAAGCTC 
GGCCTCCTGG GTGACTCTGT GGACATCTTC AAGGGCATCC CCTTCGCAGC TCCCACCAAG 
GCCCTGGAAA ATCCTCAGCC ACATCCTGGC TGGCAAGGGA CCCTGAAGGC CAAGAACTTC 
AAGAAGAGAT GCCTGCAGGC CACCATCACC CAGGACAGCA CCTACGGGGA TGAAGACTGC 
CTGTACCTCA ACATTTGGGT GCCCCAGGGC AGGAAGCAAG TCTCCCGGGA CCTGCCCGTT 
ATGATCTGGA TCTATGGAGG CGCCTTCCTC ATGGGGTCCG GCCATGGGGC CAACTTCCTC 
AACAACTACC TGTATGACGG CGAGGAGATC GCCACACGCG GAAACGTCAT CGTGGTCACC 
TTCAACTACC GTGTCGGCCC CCTTGGGTTC CTCAGCACTG GGGACGCCAA TCTGCCAGGT 
AACTATGGCC TTCGGGATCA GCACATGGCC ATTGCTTGGG TGAAGAGGAA TATCGCGGCC 
TTCGGGGGGG ACCCCAACAA CATCACGCTC TTCGGGGAGT CTGCTGGAGG TGCCAGCGTC 
TCTCTGCAGA CCCTCTCCCC CTACAACAAG GGCCTCATCC GGCGAGCCAT CAGCCAGAGC 
GGCGTGGCCC TGAGTCCCTG GGTCATCCAG AAAAACCCAC TCTTCTGGGC CAAAAAGGTG 
GCTGAGAAGG TGGGTTGCCC TGTGGGTGAT GCCGCCAGGA TGGCCCAGTG TCTGAAGGTT 
ACTGATCCCC GAGCCCTGAC GCTGGCCTAT AAGGTGCCGC TGGCAGGCCT GGAGTACCCC 
ATGCTGCACT ATGTGGGCTT CGTCCCTGTC ATTGATGGAG ACTTCATCCC CGCTGACCCG 
ATCAACCTGT ACGCCAACGC CGCCGACATC GACTATATAG CAGGCACCAA CAACATGGAC 
GGCCACATCT TCGCCAGCAT CGACATGCCT GCCATCAACA AGGGCAACAA GAAAGTCACG 
GAGGAGGACT TCTACAAGCT GGTCAGTGAG TTCACAATCA CCAAGGGGCT CAGAGGCGCC 
AAGACGACCT TTGATGTCTA CACCGAGTCC TGGGCCCAGG ACCCATCCCA GGAGAATAAG 
AAGAAGACTG TGGTGGACTT TGAGACCGAT GTCCTCTTCC TGGTGCCCAC CGAGATTGCC 
CTAGCCCAGC ACAGAGCCAA TGCCAAGAGT GCCAAGACCT ACGCCTACCT GTTTTCCCAT 
CCCTCTCGGA TGCCCGTCTA CCCCAAATGG GTGGGGGCCG ACCATGCAGA TGACATTCAG 
TACGTTTTCG GGAAGCCCTT CGCCACCCCC ACGGGCTACC GGCCCCAAGA CAGGACAGTC 
TCTAAGGCCA TGATCGCCTA CTGGACCAAC TTTGCCAAAA CAGGGGACCC CAACATGGGC 
GACTCGGCTG TGCCCACACA CTGGGAACCC TACACTACGG AAAACAGCGG CTACCTGGAG 
ATCACCAAGA AGATGGGCAG CAGCTCCATG AAGCGGAGCC TGAGAACCAA CTTCCTGCGC 
TACTGGACCC TCACCTATCT GGCGCTGCCC ACAGTGACCG ACCAGGAGGC CACCCCTGTG 
CCCCCCACAG GGGACTCCGA GGCCACTCCC GTGCCCCCCA CGGGTGACTC CGAGACCGCC 
CCCGTGCCGC CCACGGGTGA CTCCGGGGCC CCCCCCGTGC CGCCCACGGG TGACTCCGGG 
GCCCCCCCCG TGCCGCCCAC GGGTGACTCC GGGGCCCCCC CCGTGCCGCC CACGGGTGAC 
TCCGGGGCCC CCCCCGTGCC GCCCACGGGT GACTCCGGGG CCCCCCCCGT GCCGCCCACG 
GGTGACTCCG GGGCCCCCCC CGTGCCGCCC ACGGGTGACT CCGGGGCCCC CCCCGTGCCG 
CCCACGGGTG ACTCCGGCGC CCCCCCCGTG CCGCCCACGG GTGACGCCGG GCCCCCCCCC 
GTGCCGCCCA CGGGTGACTC CGGCGCCCCC CCCGTGCCGC CCACGGGTGA CTCCGGGGCC 
CCCCCCGTGA CCCCCACGGG TGACTCCGAG ACCGCCCCCG TGCCGCCCAC GGGTGACTCC 
GGGGCCCCCC CTGTGCCCCC CACGGGTGAC TCTGAGGCTG CCCCTGTGCC CCCCACAGAT 
GACTCCAAGG AAGCTCAGAT GCCTGCAGTC ATTAGGTTTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CEL ( NM_001807.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001798.2 Homo sapiens carboxyl ester lipase (CEL), mRNA.

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CloneID	OHu22073
Clone ID Related Accession (Same CDS sequence)	NM_001807.4
Accession Version	NM_001807.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2271bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	bile salt-activated lipase precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL162417.23, BC042510.1, AF081673.1, AK299965.1 and BE045879.1. This sequence is a reference standard in the RefSeqGene project. On Jan 4, 2013 this sequence version replaced NM_001807.3. Sequence Note: The 3' terminal exon of this RefSeq is inferred based on aligning transcripts. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCTCACCA TGGGGCGCCT GCAACTGGTT GTGTTGGGCC TCACCTGCTG CTGGGCAGTG 
GCGAGTGCCG CGAAGCTGGG CGCCGTGTAC ACAGAAGGTG GGTTCGTGGA AGGCGTCAAT 
AAGAAGCTCG GCCTCCTGGG TGACTCTGTG GACATCTTCA AGGGCATCCC CTTCGCAGCT 
CCCACCAAGG CCCTGGAAAA TCCTCAGCCA CATCCTGGCT GGCAAGGGAC CCTGAAGGCC 
AAGAACTTCA AGAAGAGATG CCTGCAGGCC ACCATCACCC AGGACAGCAC CTACGGGGAT 
GAAGACTGCC TGTACCTCAA CATTTGGGTG CCCCAGGGCA GGAAGCAAGT CTCCCGGGAC 
CTGCCCGTTA TGATCTGGAT CTATGGAGGC GCCTTCCTCA TGGGGTCCGG CCATGGGGCC 
AACTTCCTCA ACAACTACCT GTATGACGGC GAGGAGATCG CCACACGCGG AAACGTCATC 
GTGGTCACCT TCAACTACCG TGTCGGCCCC CTTGGGTTCC TCAGCACTGG GGACGCCAAT 
CTGCCAGGTA ACTATGGCCT TCGGGATCAG CACATGGCCA TTGCTTGGGT GAAGAGGAAT 
ATCGCGGCCT TCGGGGGGGA CCCCAACAAC ATCACGCTCT TCGGGGAGTC TGCTGGAGGT 
GCCAGCGTCT CTCTGCAGAC CCTCTCCCCC TACAACAAGG GCCTCATCCG GCGAGCCATC 
AGCCAGAGCG GCGTGGCCCT GAGTCCCTGG GTCATCCAGA AAAACCCACT CTTCTGGGCC 
AAAAAGGTGG CTGAGAAGGT GGGTTGCCCT GTGGGTGATG CCGCCAGGAT GGCCCAGTGT 
CTGAAGGTTA CTGATCCCCG AGCCCTGACG CTGGCCTATA AGGTGCCGCT GGCAGGCCTG 
GAGTACCCCA TGCTGCACTA TGTGGGCTTC GTCCCTGTCA TTGATGGAGA CTTCATCCCC 
GCTGACCCGA TCAACCTGTA CGCCAACGCC GCCGACATCG ACTATATAGC AGGCACCAAC 
AACATGGACG GCCACATCTT CGCCAGCATC GACATGCCTG CCATCAACAA GGGCAACAAG 
AAAGTCACGG AGGAGGACTT CTACAAGCTG GTCAGTGAGT TCACAATCAC CAAGGGGCTC 
AGAGGCGCCA AGACGACCTT TGATGTCTAC ACCGAGTCCT GGGCCCAGGA CCCATCCCAG 
GAGAATAAGA AGAAGACTGT GGTGGACTTT GAGACCGATG TCCTCTTCCT GGTGCCCACC 
GAGATTGCCC TAGCCCAGCA CAGAGCCAAT GCCAAGAGTG CCAAGACCTA CGCCTACCTG 
TTTTCCCATC CCTCTCGGAT GCCCGTCTAC CCCAAATGGG TGGGGGCCGA CCATGCAGAT 
GACATTCAGT ACGTTTTCGG GAAGCCCTTC GCCACCCCCA CGGGCTACCG GCCCCAAGAC 
AGGACAGTCT CTAAGGCCAT GATCGCCTAC TGGACCAACT TTGCCAAAAC AGGGGACCCC 
AACATGGGCG ACTCGGCTGT GCCCACACAC TGGGAACCCT ACACTACGGA AAACAGCGGC 
TACCTGGAGA TCACCAAGAA GATGGGCAGC AGCTCCATGA AGCGGAGCCT GAGAACCAAC 
TTCCTGCGCT ACTGGACCCT CACCTATCTG GCGCTGCCCA CAGTGACCGA CCAGGAGGCC 
ACCCCTGTGC CCCCCACAGG GGACTCCGAG GCCACTCCCG TGCCCCCCAC GGGTGACTCC 
GAGACCGCCC CCGTGCCGCC CACGGGTGAC TCCGGGGCCC CCCCCGTGCC GCCCACGGGT 
GACTCCGGGG CCCCCCCCGT GCCGCCCACG GGTGACTCCG GGGCCCCCCC CGTGCCGCCC 
ACGGGTGACT CCGGGGCCCC CCCCGTGCCG CCCACGGGTG ACTCCGGGGC CCCCCCCGTG 
CCGCCCACGG GTGACTCCGG GGCCCCCCCC GTGCCGCCCA CGGGTGACTC CGGGGCCCCC 
CCCGTGCCGC CCACGGGTGA CTCCGGCGCC CCCCCCGTGC CGCCCACGGG TGACGCCGGG 
CCCCCCCCCG TGCCGCCCAC GGGTGACTCC GGCGCCCCCC CCGTGCCGCC CACGGGTGAC 
TCCGGGGCCC CCCCCGTGAC CCCCACGGGT GACTCCGAGA CCGCCCCCGT GCCGCCCACG 
GGTGACTCCG GGGCCCCCCC TGTGCCCCCC ACGGGTGACT CTGAGGCTGC CCCTGTGCCC 
CCCACAGATG ACTCCAAGGA AGCTCAGATG CCTGCAGTCA TTAGGTTTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001798.2
CDS	17..2287
Translation	MLTMGRLQLVVLGLTCCWAVASAAKLGAVYTEGGFVEGVNKKLGLLGDSVDIFKGIPFAAPTKALENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPRALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYANAADIDYIAGTNNMDGHIFASIDMPAINKGNKKVTEEDFYKLVSEFTITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPSRMPVYPKWVGADHADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKMGSSSMKRSLRTNFLRYWTLTYLALPTVTDQEATPVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPPTDDSKEAQMPAVIRF

Target ORF information:

RefSeq Version	NM_001807.4
Organism	Homo sapiens(human)
Definition	Homo sapiens carboxyl ester lipase (CEL), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001807.4

ORF Insert Sequence:

ATGCTCACCA TGGGGCGCCT GCAACTGGTT GTGTTGGGCC TCACCTGCTG CTGGGCAGTG 
GCGAGTGCCG CGAAGCTGGG CGCCGTGTAC ACAGAAGGTG GGTTCGTGGA AGGCGTCAAT 
AAGAAGCTCG GCCTCCTGGG TGACTCTGTG GACATCTTCA AGGGCATCCC CTTCGCAGCT 
CCCACCAAGG CCCTGGAAAA TCCTCAGCCA CATCCTGGCT GGCAAGGGAC CCTGAAGGCC 
AAGAACTTCA AGAAGAGATG CCTGCAGGCC ACCATCACCC AGGACAGCAC CTACGGGGAT 
GAAGACTGCC TGTACCTCAA CATTTGGGTG CCCCAGGGCA GGAAGCAAGT CTCCCGGGAC 
CTGCCCGTTA TGATCTGGAT CTATGGAGGC GCCTTCCTCA TGGGGTCCGG CCATGGGGCC 
AACTTCCTCA ACAACTACCT GTATGACGGC GAGGAGATCG CCACACGCGG AAACGTCATC 
GTGGTCACCT TCAACTACCG TGTCGGCCCC CTTGGGTTCC TCAGCACTGG GGACGCCAAT 
CTGCCAGGTA ACTATGGCCT TCGGGATCAG CACATGGCCA TTGCTTGGGT GAAGAGGAAT 
ATCGCGGCCT TCGGGGGGGA CCCCAACAAC ATCACGCTCT TCGGGGAGTC TGCTGGAGGT 
GCCAGCGTCT CTCTGCAGAC CCTCTCCCCC TACAACAAGG GCCTCATCCG GCGAGCCATC 
AGCCAGAGCG GCGTGGCCCT GAGTCCCTGG GTCATCCAGA AAAACCCACT CTTCTGGGCC 
AAAAAGGTGG CTGAGAAGGT GGGTTGCCCT GTGGGTGATG CCGCCAGGAT GGCCCAGTGT 
CTGAAGGTTA CTGATCCCCG AGCCCTGACG CTGGCCTATA AGGTGCCGCT GGCAGGCCTG 
GAGTACCCCA TGCTGCACTA TGTGGGCTTC GTCCCTGTCA TTGATGGAGA CTTCATCCCC 
GCTGACCCGA TCAACCTGTA CGCCAACGCC GCCGACATCG ACTATATAGC AGGCACCAAC 
AACATGGACG GCCACATCTT CGCCAGCATC GACATGCCTG CCATCAACAA GGGCAACAAG 
AAAGTCACGG AGGAGGACTT CTACAAGCTG GTCAGTGAGT TCACAATCAC CAAGGGGCTC 
AGAGGCGCCA AGACGACCTT TGATGTCTAC ACCGAGTCCT GGGCCCAGGA CCCATCCCAG 
GAGAATAAGA AGAAGACTGT GGTGGACTTT GAGACCGATG TCCTCTTCCT GGTGCCCACC 
GAGATTGCCC TAGCCCAGCA CAGAGCCAAT GCCAAGAGTG CCAAGACCTA CGCCTACCTG 
TTTTCCCATC CCTCTCGGAT GCCCGTCTAC CCCAAATGGG TGGGGGCCGA CCATGCAGAT 
GACATTCAGT ACGTTTTCGG GAAGCCCTTC GCCACCCCCA CGGGCTACCG GCCCCAAGAC 
AGGACAGTCT CTAAGGCCAT GATCGCCTAC TGGACCAACT TTGCCAAAAC AGGGGACCCC 
AACATGGGCG ACTCGGCTGT GCCCACACAC TGGGAACCCT ACACTACGGA AAACAGCGGC 
TACCTGGAGA TCACCAAGAA GATGGGCAGC AGCTCCATGA AGCGGAGCCT GAGAACCAAC 
TTCCTGCGCT ACTGGACCCT CACCTATCTG GCGCTGCCCA CAGTGACCGA CCAGGAGGCC 
ACCCCTGTGC CCCCCACAGG GGACTCCGAG GCCACTCCCG TGCCCCCCAC GGGTGACTCC 
GAGACCGCCC CCGTGCCGCC CACGGGTGAC TCCGGGGCCC CCCCCGTGCC GCCCACGGGT 
GACTCCGGGG CCCCCCCCGT GCCGCCCACG GGTGACTCCG GGGCCCCCCC CGTGCCGCCC 
ACGGGTGACT CCGGGGCCCC CCCCGTGCCG CCCACGGGTG ACTCCGGGGC CCCCCCCGTG 
CCGCCCACGG GTGACTCCGG GGCCCCCCCC GTGCCGCCCA CGGGTGACTC CGGGGCCCCC 
CCCGTGCCGC CCACGGGTGA CTCCGGCGCC CCCCCCGTGC CGCCCACGGG TGACGCCGGG 
CCCCCCCCCG TGCCGCCCAC GGGTGACTCC GGCGCCCCCC CCGTGCCGCC CACGGGTGAC 
TCCGGGGCCC CCCCCGTGAC CCCCACGGGT GACTCCGAGA CCGCCCCCGT GCCGCCCACG 
GGTGACTCCG GGGCCCCCCC TGTGCCCCCC ACGGGTGACT CTGAGGCTGC CCCTGTGCCC 
CCCACAGATG ACTCCAAGGA AGCTCAGATG CCTGCAGTCA TTAGGTTTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Copy number variants and VNTR length polymorphisms of the carboxyl-ester lipase (CEL) gene as risk factors in pancreatic cancer.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]17(1)83-88(2017 Jan - Feb)
Dalva M,El Jellas K,Steine SJ,Johansson BB,Ringdal M,Torsvik J,Immervoll H,Hoem D,Laemmerhirt F,Simon P,Lerch MM,Johansson S,Nj?lstad PR,Weiss FU,Fjeld K,Molven A

Length of Variable Numbers of Tandem Repeats in the Carboxyl Ester Lipase (CEL) Gene May Confer Susceptibility to Alcoholic Liver Cirrhosis but Not Alcoholic Chronic Pancreatitis.
PloS one11(11)e0165567(2016)
Fjeld K,Beer S,Johnstone M,Zimmer C,M?ssner J,Ruffert C,Krehan M,Zapf C,Nj?lstad PR,Johansson S,Bugert P,Miyajima F,Liloglou T,Brown LJ,Winn SA,Davies K,Latawiec D,Gunson BK,Criddle DN,Pirmohamed M,Gr?tzmann R,Michl P,Greenhalf W,Molven A,Sutton R,Rosendahl J

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CEL cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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