APPBP2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	APPBP2
Entrez Gene ID	10513
Full Name	amyloid beta precursor protein binding protein 2
Synonyms	APP-BP2,HS.84084,PAT1
General protein information	Preferred Names amyloid beta precursor protein binding protein 2 Names amyloid protein-binding protein 2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 protein interacting with APP tail 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q23.2
Summary	The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. The encoded protein may be involved in regulating cell death. This gene has been found to be highly expressed in breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013].
Disorder MIM:	605324

mRNA and Protein(s)

mRNA	Protein	Name
NM_006380.4	NP_006371.2	amyloid protein-binding protein 2 isoform 1
XM_011524199.2	XP_011522501.1	amyloid protein-binding protein 2 isoform X2
NM_001282476.1	NP_001269405.1	amyloid protein-binding protein 2 isoform 2
NM_006380.5	NP_006371.2	amyloid protein-binding protein 2 isoform 1
NM_006380.3	NP_006371.2	amyloid protein-binding protein 2 isoform 1
XM_011524198.2	XP_011522500.1	amyloid protein-binding protein 2 isoform X1
XM_011524198.3	XP_011522500.1	amyloid protein-binding protein 2 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	APPBP2	XP_001136833.2
Mus musculus (house mouse)	Appbp2	NP_080101.1
Gallus gallus (chicken)	APPBP2	NP_001025894.1
Homo sapiens (human)	APPBP2	NP_006371.2
	APPBP2	XP_001107544.2
Canis lupus familiaris (dog)	APPBP2	XP_537708.2
Bos taurus (cattle)	APPBP2	XP_002695688.2
Rattus norvegicus (Norway rat)	Appbp2	NP_001094439.1
Danio rerio (zebrafish)	appbp2	NP_997798.1
Drosophila melanogaster (fruit fly)	Pat1	NP_572328.1
Xenopus tropicalis (tropical clawed frog)	appbp2	XP_002933870.1

Gene Ontology
Bibliography

Related articles in PubMed

Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.
So J, Pasculescu A, Dai AY, Williton K, James A, Nguyen V, Creixell P, Schoof EM, Sinclair J, Barrios-Rodiles M, Gu J, Krizus A, Williams R, Olhovsky M, Dennis JW, Wrana JL, Linding R, Jorgensen C, Pawson T, Colwill K
Science signaling8(371)rs3(2015 Apr)

Amyloid-? precursor protein facilitates the regulator of calcineurin 1-mediated apoptosis by downregulating proteasome subunit ? type-5 and proteasome subunit ? type-7.
Wu Y, Deng Y, Zhang S, Luo Y, Cai F, Zhang Z, Zhou W, Li T, Song W
Neurobiology of aging36(1)169-77(2015 Jan)

PAT1 induces cell death signal and SET mislocalization into the cytoplasm by increasing APP/APLP2 at the cell surface.
Briand S, Facchinetti P, Clamagirand C, Madeira A, Pommet JM, Pimplikar SW, Allinquant B
Neurobiology of aging32(6)1099-113(2011 Jun)

Pat1 proteins: a life in translation, translation repression and mRNA decay.
Marnef A, Standart N
Biochemical Society transactions38(6)1602-7(2010 Dec)

Association of the herpes simplex virus type 1 Us11 gene product with the cellular kinesin light-chain-related protein PAT1 results in the redistribution of both polypeptides.
Benboudjema L, Mulvey M, Gao Y, Pimplikar SW, Mohr I
Journal of virology77(17)9192-203(2003 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

It facilitates the regulator of calcineurin 1-mediated apoptosis by downregulating proteasome subunits.
Title: Amyloid-? precursor protein facilitates the regulator of calcineurin 1-mediated apoptosis by downregulating proteasome subunit ? type-5 and proteasome subunit ? type-7.

Association of the herpes simplex virus type 1 Us11 gene product with the cellular kinesin light-chain-related protein PAT1 results in the redistribution of both polypeptides.
Title: Association of the herpes simplex virus type 1 Us11 gene product with the cellular kinesin light-chain-related protein PAT1 results in the redistribution of both polypeptides.

The following APPBP2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the APPBP2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu01798	NM_006380.5 Latest version!	Homo sapiens amyloid beta precursor protein binding protein 2 (APPBP2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu64078	XM_011524198.3 Latest version!	Homo sapiens amyloid beta precursor protein binding protein 2 (APPBP2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
OHu64079	XM_011524199.2 Latest version!	Homo sapiens amyloid beta precursor protein binding protein 2 (APPBP2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
OHu08252	NM_001282476.1 Latest version!	Homo sapiens amyloid beta precursor protein binding protein 2 (APPBP2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
View Old Accession Versions >>
OHu01798	NM_006380.4	Homo sapiens amyloid beta precursor protein binding protein 2 (APPBP2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu01798	NM_006380.3	Homo sapiens amyloid beta precursor protein binding protein 2 (APPBP2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu64078	XM_011524198.2	Homo sapiens amyloid beta precursor protein binding protein 2 (APPBP2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

APPBP2 ( NM_006380.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_006371.2 Homo sapiens amyloid beta precursor protein binding protein 2 (APPBP2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu01798
Clone ID Related Accession (Same CDS sequence)	NM_006380.4 , NM_006380.5 , NM_006380.3
Accession Version	NM_006380.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1758bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Homo sapiens(human)
Product	amyloid protein-binding protein 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC011921.14, BP222365.1, D86981.1 and AC037475.9. On Nov 22, 2018 this sequence version replaced NM_006380.3. Transcript Variant: This variant (1) represents the longer transcript and the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.31040.1, D86981.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGCCG TGGAACTAGA GTGGATCCCA GAGACTCTCT ATAACACCGC CATCTCCGCT 
GTCGTGGACA ACTACATCCG CTCCCGCCGA GACATCCGCT CCTTGCCCGA GAACATCCAG 
TTTGATGTTT ACTACAAGCT TTACCAACAG GGACGCTTAT GTCAACTGGG CAGTGAATTT 
TGTGAATTGG AAGTTTTTGC TAAAGTACTG AGAGCTTTGG ATAAAAGACA TTTGCTTCAT 
CATTGTTTTC AGGCTTTGAT GGATCATGGT GTTAAAGTTG CTTCAGTCTT GGCCTACTCA 
TTCAGTAGGC GGTGCTCTTA TATAGCAGAA TCAGATGCTG CAGTAAAGGA AAAAGCCATT 
CAGGTTGGCT TTGTTTTAGG TGGCTTTCTT TCAGATGCAG GCTGGTACAG TGATGCTGAG 
AAAGTTTTTC TGTCCTGCCT TCAGTTGTGT ACTCTACACG ATGAGATGCT TCATTGGTTT 
CGTGCAGTAG AATGTTGTGT GAGGTTGCTT CATGTGCGAA ATGGAAACTG CAAATATCAT 
TTGGGTGAAG AAACATTTAA ATTAGCTCAG ACATATATGG ATAAACTATC AAAACATGGC 
CAGCAAGCAA ATAAAGCTGC ACTCTATGGA GAACTGTGTG CACTCCTATT TGCAAAAAGT 
CACTATGATG AGGCATACAA ATGGTGCATC GAGGCAATGA AAGAAATTAC AGCAGGCTTA 
CCAGTGAAAG TTGTGGTGGA TGTCTTAAGA CAAGCTTCTA AGGCTTGTGT AGTAAAACGT 
GAATTTAAGA AGGCAGAACA GTTAATTAAA CATGCAGTGT ATTTGGCACG GGATCATTTT 
GGATCCAAAC ACCCAAAATA TTCTGATACA CTGCTAGATT ATGGGTTCTA CTTACTCAAT 
GTAGATAATA TCTGTCAGTC TGTTGCAATT TATCAGGCAG CCCTTGACAT TAGACAGTCA 
GTGTTTGGTG GCAAAAATAT CCACGTAGCA ACAGCTCATG AAGATTTGGC CTACTCTTCT 
TATGTCCACC AGTATAGCTC TGGGAAATTT GACAATGCAC TATTTCATGC AGAAAGAGCT 
ATTGGTATCA TTACCCACAT CCTACCTGAA GATCATCTTC TTTTGGCTTC TTCAAAGAGG 
GTGAAAGCAC TTATTTTAGA GGAGATTGCA ATTGATTGTC ATAATAAGGA AACTGAACAG 
AGGCTGCTTC AAGAAGCTCA TGATTTGCAC CTGTCTTCAC TCCAACTAGC TAAAAAAGCT 
TTTGGGGAAT TTAATGTACA GACTGCAAAA CACTATGGAA ACCTTGGAAG ACTTTATCAG 
TCAATGAGAA AATTTAAGGA AGCTGAAGAA ATGCACATCA AAGCAATTCA GATTAAAGAA 
CAACTTCTTG GTCAAGAAGA TTATGAAGTA GCCCTTTCAG TGGGACATCT GGCTTCTTTA 
TATAATTATG ACATGAATCA GTATGAAAAT GCTGAGAAAC TTTATTTGCG ATCTATAGCA 
ATTGGGAAGA AACTTTTTGG TGAGGGCTAC AGTGGACTAG AATATGATTA TCGAGGTCTC 
ATTAAACTTT ACAACTCCAT TGGAAATTAC GAGAAAGTGT TTGAATATCA CAATGTTCTG 
TCTAACTGGA ACCGGTTGCG AGATCGGCAA TATTCAGTGA CAGATGCTCT TGAAGATGTC 
AGCACCAGCC CCCAGTCCAC TGAAGAAGTG GTGCAGTCCT TCCTGATTTC TCAGAATGTC 
GAGGGACCGA GCTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006371.2
CDS	312..2069
Translation	MAAVELEWIPETLYNTAISAVVDNYIRSRRDIRSLPENIQFDVYYKLYQQGRLCQLGSEFCELEVFAKVLRALDKRHLLHHCFQALMDHGVKVASVLAYSFSRRCSYIAESDAAVKEKAIQVGFVLGGFLSDAGWYSDAEKVFLSCLQLCTLHDEMLHWFRAVECCVRLLHVRNGNCKYHLGEETFKLAQTYMDKLSKHGQQANKAALYGELCALLFAKSHYDEAYKWCIEAMKEITAGLPVKVVVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLNVDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEKVFEYHNVLSNWNRLRDRQYSVTDALEDVSTSPQSTEEVVQSFLISQNVEGPSC

Target ORF information:

RefSeq Version	NM_006380.4
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor protein binding protein 2 (APPBP2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006380.4

ORF Insert Sequence:

ATGGCGGCCG TGGAACTAGA GTGGATCCCA GAGACTCTCT ATAACACCGC CATCTCCGCT 
GTCGTGGACA ACTACATCCG CTCCCGCCGA GACATCCGCT CCTTGCCCGA GAACATCCAG 
TTTGATGTTT ACTACAAGCT TTACCAACAG GGACGCTTAT GTCAACTGGG CAGTGAATTT 
TGTGAATTGG AAGTTTTTGC TAAAGTACTG AGAGCTTTGG ATAAAAGACA TTTGCTTCAT 
CATTGTTTTC AGGCTTTGAT GGATCATGGT GTTAAAGTTG CTTCAGTCTT GGCCTACTCA 
TTCAGTAGGC GGTGCTCTTA TATAGCAGAA TCAGATGCTG CAGTAAAGGA AAAAGCCATT 
CAGGTTGGCT TTGTTTTAGG TGGCTTTCTT TCAGATGCAG GCTGGTACAG TGATGCTGAG 
AAAGTTTTTC TGTCCTGCCT TCAGTTGTGT ACTCTACACG ATGAGATGCT TCATTGGTTT 
CGTGCAGTAG AATGTTGTGT GAGGTTGCTT CATGTGCGAA ATGGAAACTG CAAATATCAT 
TTGGGTGAAG AAACATTTAA ATTAGCTCAG ACATATATGG ATAAACTATC AAAACATGGC 
CAGCAAGCAA ATAAAGCTGC ACTCTATGGA GAACTGTGTG CACTCCTATT TGCAAAAAGT 
CACTATGATG AGGCATACAA ATGGTGCATC GAGGCAATGA AAGAAATTAC AGCAGGCTTA 
CCAGTGAAAG TTGTGGTGGA TGTCTTAAGA CAAGCTTCTA AGGCTTGTGT AGTAAAACGT 
GAATTTAAGA AGGCAGAACA GTTAATTAAA CATGCAGTGT ATTTGGCACG GGATCATTTT 
GGATCCAAAC ACCCAAAATA TTCTGATACA CTGCTAGATT ATGGGTTCTA CTTACTCAAT 
GTAGATAATA TCTGTCAGTC TGTTGCAATT TATCAGGCAG CCCTTGACAT TAGACAGTCA 
GTGTTTGGTG GCAAAAATAT CCACGTAGCA ACAGCTCATG AAGATTTGGC CTACTCTTCT 
TATGTCCACC AGTATAGCTC TGGGAAATTT GACAATGCAC TATTTCATGC AGAAAGAGCT 
ATTGGTATCA TTACCCACAT CCTACCTGAA GATCATCTTC TTTTGGCTTC TTCAAAGAGG 
GTGAAAGCAC TTATTTTAGA GGAGATTGCA ATTGATTGTC ATAATAAGGA AACTGAACAG 
AGGCTGCTTC AAGAAGCTCA TGATTTGCAC CTGTCTTCAC TCCAACTAGC TAAAAAAGCT 
TTTGGGGAAT TTAATGTACA GACTGCAAAA CACTATGGAA ACCTTGGAAG ACTTTATCAG 
TCAATGAGAA AATTTAAGGA AGCTGAAGAA ATGCACATCA AAGCAATTCA GATTAAAGAA 
CAACTTCTTG GTCAAGAAGA TTATGAAGTA GCCCTTTCAG TGGGACATCT GGCTTCTTTA 
TATAATTATG ACATGAATCA GTATGAAAAT GCTGAGAAAC TTTATTTGCG ATCTATAGCA 
ATTGGGAAGA AACTTTTTGG TGAGGGCTAC AGTGGACTAG AATATGATTA TCGAGGTCTC 
ATTAAACTTT ACAACTCCAT TGGAAATTAC GAGAAAGTGT TTGAATATCA CAATGTTCTG 
TCTAACTGGA ACCGGTTGCG AGATCGGCAA TATTCAGTGA CAGATGCTCT TGAAGATGTC 
AGCACCAGCC CCCAGTCCAC TGAAGAAGTG GTGCAGTCCT TCCTGATTTC TCAGAATGTC 
GAGGGACCGA GCTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APPBP2 ( NM_006380.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_006371.2 Homo sapiens amyloid beta precursor protein binding protein 2 (APPBP2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu01798
Clone ID Related Accession (Same CDS sequence)	NM_006380.4 , NM_006380.5 , NM_006380.3
Accession Version	NM_006380.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1758bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-14
Organism	Homo sapiens(human)
Product	amyloid protein-binding protein 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC011921.14 and AC037475.9. On Aug 31, 2019 this sequence version replaced NM_006380.4. Transcript Variant: This variant (1) represents the longer transcript and the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: D86981.1, SRR1660807.31040.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000083182.8/ ENSP00000083182.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGCCG TGGAACTAGA GTGGATCCCA GAGACTCTCT ATAACACCGC CATCTCCGCT 
GTCGTGGACA ACTACATCCG CTCCCGCCGA GACATCCGCT CCTTGCCCGA GAACATCCAG 
TTTGATGTTT ACTACAAGCT TTACCAACAG GGACGCTTAT GTCAACTGGG CAGTGAATTT 
TGTGAATTGG AAGTTTTTGC TAAAGTACTG AGAGCTTTGG ATAAAAGACA TTTGCTTCAT 
CATTGTTTTC AGGCTTTGAT GGATCATGGT GTTAAAGTTG CTTCAGTCTT GGCCTACTCA 
TTCAGTAGGC GGTGCTCTTA TATAGCAGAA TCAGATGCTG CAGTAAAGGA AAAAGCCATT 
CAGGTTGGCT TTGTTTTAGG TGGCTTTCTT TCAGATGCAG GCTGGTACAG TGATGCTGAG 
AAAGTTTTTC TGTCCTGCCT TCAGTTGTGT ACTCTACACG ATGAGATGCT TCATTGGTTT 
CGTGCAGTAG AATGTTGTGT GAGGTTGCTT CATGTGCGAA ATGGAAACTG CAAATATCAT 
TTGGGTGAAG AAACATTTAA ATTAGCTCAG ACATATATGG ATAAACTATC AAAACATGGC 
CAGCAAGCAA ATAAAGCTGC ACTCTATGGA GAACTGTGTG CACTCCTATT TGCAAAAAGT 
CACTATGATG AGGCATACAA ATGGTGCATC GAGGCAATGA AAGAAATTAC AGCAGGCTTA 
CCAGTGAAAG TTGTGGTGGA TGTCTTAAGA CAAGCTTCTA AGGCTTGTGT AGTAAAACGT 
GAATTTAAGA AGGCAGAACA GTTAATTAAA CATGCAGTGT ATTTGGCACG GGATCATTTT 
GGATCCAAAC ACCCAAAATA TTCTGATACA CTGCTAGATT ATGGGTTCTA CTTACTCAAT 
GTAGATAATA TCTGTCAGTC TGTTGCAATT TATCAGGCAG CCCTTGACAT TAGACAGTCA 
GTGTTTGGTG GCAAAAATAT CCACGTAGCA ACAGCTCATG AAGATTTGGC CTACTCTTCT 
TATGTCCACC AGTATAGCTC TGGGAAATTT GACAATGCAC TATTTCATGC AGAAAGAGCT 
ATTGGTATCA TTACCCACAT CCTACCTGAA GATCATCTTC TTTTGGCTTC TTCAAAGAGG 
GTGAAAGCAC TTATTTTAGA GGAGATTGCA ATTGATTGTC ATAATAAGGA AACTGAACAG 
AGGCTGCTTC AAGAAGCTCA TGATTTGCAC CTGTCTTCAC TCCAACTAGC TAAAAAAGCT 
TTTGGGGAAT TTAATGTACA GACTGCAAAA CACTATGGAA ACCTTGGAAG ACTTTATCAG 
TCAATGAGAA AATTTAAGGA AGCTGAAGAA ATGCACATCA AAGCAATTCA GATTAAAGAA 
CAACTTCTTG GTCAAGAAGA TTATGAAGTA GCCCTTTCAG TGGGACATCT GGCTTCTTTA 
TATAATTATG ACATGAATCA GTATGAAAAT GCTGAGAAAC TTTATTTGCG ATCTATAGCA 
ATTGGGAAGA AACTTTTTGG TGAGGGCTAC AGTGGACTAG AATATGATTA TCGAGGTCTC 
ATTAAACTTT ACAACTCCAT TGGAAATTAC GAGAAAGTGT TTGAATATCA CAATGTTCTG 
TCTAACTGGA ACCGGTTGCG AGATCGGCAA TATTCAGTGA CAGATGCTCT TGAAGATGTC 
AGCACCAGCC CCCAGTCCAC TGAAGAAGTG GTGCAGTCCT TCCTGATTTC TCAGAATGTC 
GAGGGACCGA GCTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006371.2
CDS	312..2069
Translation	MAAVELEWIPETLYNTAISAVVDNYIRSRRDIRSLPENIQFDVYYKLYQQGRLCQLGSEFCELEVFAKVLRALDKRHLLHHCFQALMDHGVKVASVLAYSFSRRCSYIAESDAAVKEKAIQVGFVLGGFLSDAGWYSDAEKVFLSCLQLCTLHDEMLHWFRAVECCVRLLHVRNGNCKYHLGEETFKLAQTYMDKLSKHGQQANKAALYGELCALLFAKSHYDEAYKWCIEAMKEITAGLPVKVVVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLNVDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEKVFEYHNVLSNWNRLRDRQYSVTDALEDVSTSPQSTEEVVQSFLISQNVEGPSC

Target ORF information:

RefSeq Version	NM_006380.5
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor protein binding protein 2 (APPBP2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006380.5

ORF Insert Sequence:

ATGGCGGCCG TGGAACTAGA GTGGATCCCA GAGACTCTCT ATAACACCGC CATCTCCGCT 
GTCGTGGACA ACTACATCCG CTCCCGCCGA GACATCCGCT CCTTGCCCGA GAACATCCAG 
TTTGATGTTT ACTACAAGCT TTACCAACAG GGACGCTTAT GTCAACTGGG CAGTGAATTT 
TGTGAATTGG AAGTTTTTGC TAAAGTACTG AGAGCTTTGG ATAAAAGACA TTTGCTTCAT 
CATTGTTTTC AGGCTTTGAT GGATCATGGT GTTAAAGTTG CTTCAGTCTT GGCCTACTCA 
TTCAGTAGGC GGTGCTCTTA TATAGCAGAA TCAGATGCTG CAGTAAAGGA AAAAGCCATT 
CAGGTTGGCT TTGTTTTAGG TGGCTTTCTT TCAGATGCAG GCTGGTACAG TGATGCTGAG 
AAAGTTTTTC TGTCCTGCCT TCAGTTGTGT ACTCTACACG ATGAGATGCT TCATTGGTTT 
CGTGCAGTAG AATGTTGTGT GAGGTTGCTT CATGTGCGAA ATGGAAACTG CAAATATCAT 
TTGGGTGAAG AAACATTTAA ATTAGCTCAG ACATATATGG ATAAACTATC AAAACATGGC 
CAGCAAGCAA ATAAAGCTGC ACTCTATGGA GAACTGTGTG CACTCCTATT TGCAAAAAGT 
CACTATGATG AGGCATACAA ATGGTGCATC GAGGCAATGA AAGAAATTAC AGCAGGCTTA 
CCAGTGAAAG TTGTGGTGGA TGTCTTAAGA CAAGCTTCTA AGGCTTGTGT AGTAAAACGT 
GAATTTAAGA AGGCAGAACA GTTAATTAAA CATGCAGTGT ATTTGGCACG GGATCATTTT 
GGATCCAAAC ACCCAAAATA TTCTGATACA CTGCTAGATT ATGGGTTCTA CTTACTCAAT 
GTAGATAATA TCTGTCAGTC TGTTGCAATT TATCAGGCAG CCCTTGACAT TAGACAGTCA 
GTGTTTGGTG GCAAAAATAT CCACGTAGCA ACAGCTCATG AAGATTTGGC CTACTCTTCT 
TATGTCCACC AGTATAGCTC TGGGAAATTT GACAATGCAC TATTTCATGC AGAAAGAGCT 
ATTGGTATCA TTACCCACAT CCTACCTGAA GATCATCTTC TTTTGGCTTC TTCAAAGAGG 
GTGAAAGCAC TTATTTTAGA GGAGATTGCA ATTGATTGTC ATAATAAGGA AACTGAACAG 
AGGCTGCTTC AAGAAGCTCA TGATTTGCAC CTGTCTTCAC TCCAACTAGC TAAAAAAGCT 
TTTGGGGAAT TTAATGTACA GACTGCAAAA CACTATGGAA ACCTTGGAAG ACTTTATCAG 
TCAATGAGAA AATTTAAGGA AGCTGAAGAA ATGCACATCA AAGCAATTCA GATTAAAGAA 
CAACTTCTTG GTCAAGAAGA TTATGAAGTA GCCCTTTCAG TGGGACATCT GGCTTCTTTA 
TATAATTATG ACATGAATCA GTATGAAAAT GCTGAGAAAC TTTATTTGCG ATCTATAGCA 
ATTGGGAAGA AACTTTTTGG TGAGGGCTAC AGTGGACTAG AATATGATTA TCGAGGTCTC 
ATTAAACTTT ACAACTCCAT TGGAAATTAC GAGAAAGTGT TTGAATATCA CAATGTTCTG 
TCTAACTGGA ACCGGTTGCG AGATCGGCAA TATTCAGTGA CAGATGCTCT TGAAGATGTC 
AGCACCAGCC CCCAGTCCAC TGAAGAAGTG GTGCAGTCCT TCCTGATTTC TCAGAATGTC 
GAGGGACCGA GCTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APPBP2 ( NM_006380.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_006371.2 Homo sapiens amyloid beta precursor protein binding protein 2 (APPBP2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu01798
Clone ID Related Accession (Same CDS sequence)	NM_006380.4 , NM_006380.5 , NM_006380.3
Accession Version	NM_006380.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1758bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	amyloid protein-binding protein 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP222365.1, D86981.1 and AC037475.9. On Sep 11, 2013 this sequence version replaced NM_006380.2. Transcript Variant: This variant (1) represents the longer transcript and the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: D86981.1, SRR1660805.258332.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCCG TGGAACTAGA GTGGATCCCA GAGACTCTCT ATAACACCGC CATCTCCGCT 
GTCGTGGACA ACTACATCCG CTCCCGCCGA GACATCCGCT CCTTGCCCGA GAACATCCAG 
TTTGATGTTT ACTACAAGCT TTACCAACAG GGACGCTTAT GTCAACTGGG CAGTGAATTT 
TGTGAATTGG AAGTTTTTGC TAAAGTACTG AGAGCTTTGG ATAAAAGACA TTTGCTTCAT 
CATTGTTTTC AGGCTTTGAT GGATCATGGT GTTAAAGTTG CTTCAGTCTT GGCCTACTCA 
TTCAGTAGGC GGTGCTCTTA TATAGCAGAA TCAGATGCTG CAGTAAAGGA AAAAGCCATT 
CAGGTTGGCT TTGTTTTAGG TGGCTTTCTT TCAGATGCAG GCTGGTACAG TGATGCTGAG 
AAAGTTTTTC TGTCCTGCCT TCAGTTGTGT ACTCTACACG ATGAGATGCT TCATTGGTTT 
CGTGCAGTAG AATGTTGTGT GAGGTTGCTT CATGTGCGAA ATGGAAACTG CAAATATCAT 
TTGGGTGAAG AAACATTTAA ATTAGCTCAG ACATATATGG ATAAACTATC AAAACATGGC 
CAGCAAGCAA ATAAAGCTGC ACTCTATGGA GAACTGTGTG CACTCCTATT TGCAAAAAGT 
CACTATGATG AGGCATACAA ATGGTGCATC GAGGCAATGA AAGAAATTAC AGCAGGCTTA 
CCAGTGAAAG TTGTGGTGGA TGTCTTAAGA CAAGCTTCTA AGGCTTGTGT AGTAAAACGT 
GAATTTAAGA AGGCAGAACA GTTAATTAAA CATGCAGTGT ATTTGGCACG GGATCATTTT 
GGATCCAAAC ACCCAAAATA TTCTGATACA CTGCTAGATT ATGGGTTCTA CTTACTCAAT 
GTAGATAATA TCTGTCAGTC TGTTGCAATT TATCAGGCAG CCCTTGACAT TAGACAGTCA 
GTGTTTGGTG GCAAAAATAT CCACGTAGCA ACAGCTCATG AAGATTTGGC CTACTCTTCT 
TATGTCCACC AGTATAGCTC TGGGAAATTT GACAATGCAC TATTTCATGC AGAAAGAGCT 
ATTGGTATCA TTACCCACAT CCTACCTGAA GATCATCTTC TTTTGGCTTC TTCAAAGAGG 
GTGAAAGCAC TTATTTTAGA GGAGATTGCA ATTGATTGTC ATAATAAGGA AACTGAACAG 
AGGCTGCTTC AAGAAGCTCA TGATTTGCAC CTGTCTTCAC TCCAACTAGC TAAAAAAGCT 
TTTGGGGAAT TTAATGTACA GACTGCAAAA CACTATGGAA ACCTTGGAAG ACTTTATCAG 
TCAATGAGAA AATTTAAGGA AGCTGAAGAA ATGCACATCA AAGCAATTCA GATTAAAGAA 
CAACTTCTTG GTCAAGAAGA TTATGAAGTA GCCCTTTCAG TGGGACATCT GGCTTCTTTA 
TATAATTATG ACATGAATCA GTATGAAAAT GCTGAGAAAC TTTATTTGCG ATCTATAGCA 
ATTGGGAAGA AACTTTTTGG TGAGGGCTAC AGTGGACTAG AATATGATTA TCGAGGTCTC 
ATTAAACTTT ACAACTCCAT TGGAAATTAC GAGAAAGTGT TTGAATATCA CAATGTTCTG 
TCTAACTGGA ACCGGTTGCG AGATCGGCAA TATTCAGTGA CAGATGCTCT TGAAGATGTC 
AGCACCAGCC CCCAGTCCAC TGAAGAAGTG GTGCAGTCCT TCCTGATTTC TCAGAATGTC 
GAGGGACCGA GCTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006371.2
CDS	310..2067
Translation	MAAVELEWIPETLYNTAISAVVDNYIRSRRDIRSLPENIQFDVYYKLYQQGRLCQLGSEFCELEVFAKVLRALDKRHLLHHCFQALMDHGVKVASVLAYSFSRRCSYIAESDAAVKEKAIQVGFVLGGFLSDAGWYSDAEKVFLSCLQLCTLHDEMLHWFRAVECCVRLLHVRNGNCKYHLGEETFKLAQTYMDKLSKHGQQANKAALYGELCALLFAKSHYDEAYKWCIEAMKEITAGLPVKVVVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLNVDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEKVFEYHNVLSNWNRLRDRQYSVTDALEDVSTSPQSTEEVVQSFLISQNVEGPSC

Target ORF information:

RefSeq Version	NM_006380.3
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor protein binding protein 2 (APPBP2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006380.3

ORF Insert Sequence:

ATGGCGGCCG TGGAACTAGA GTGGATCCCA GAGACTCTCT ATAACACCGC CATCTCCGCT 
GTCGTGGACA ACTACATCCG CTCCCGCCGA GACATCCGCT CCTTGCCCGA GAACATCCAG 
TTTGATGTTT ACTACAAGCT TTACCAACAG GGACGCTTAT GTCAACTGGG CAGTGAATTT 
TGTGAATTGG AAGTTTTTGC TAAAGTACTG AGAGCTTTGG ATAAAAGACA TTTGCTTCAT 
CATTGTTTTC AGGCTTTGAT GGATCATGGT GTTAAAGTTG CTTCAGTCTT GGCCTACTCA 
TTCAGTAGGC GGTGCTCTTA TATAGCAGAA TCAGATGCTG CAGTAAAGGA AAAAGCCATT 
CAGGTTGGCT TTGTTTTAGG TGGCTTTCTT TCAGATGCAG GCTGGTACAG TGATGCTGAG 
AAAGTTTTTC TGTCCTGCCT TCAGTTGTGT ACTCTACACG ATGAGATGCT TCATTGGTTT 
CGTGCAGTAG AATGTTGTGT GAGGTTGCTT CATGTGCGAA ATGGAAACTG CAAATATCAT 
TTGGGTGAAG AAACATTTAA ATTAGCTCAG ACATATATGG ATAAACTATC AAAACATGGC 
CAGCAAGCAA ATAAAGCTGC ACTCTATGGA GAACTGTGTG CACTCCTATT TGCAAAAAGT 
CACTATGATG AGGCATACAA ATGGTGCATC GAGGCAATGA AAGAAATTAC AGCAGGCTTA 
CCAGTGAAAG TTGTGGTGGA TGTCTTAAGA CAAGCTTCTA AGGCTTGTGT AGTAAAACGT 
GAATTTAAGA AGGCAGAACA GTTAATTAAA CATGCAGTGT ATTTGGCACG GGATCATTTT 
GGATCCAAAC ACCCAAAATA TTCTGATACA CTGCTAGATT ATGGGTTCTA CTTACTCAAT 
GTAGATAATA TCTGTCAGTC TGTTGCAATT TATCAGGCAG CCCTTGACAT TAGACAGTCA 
GTGTTTGGTG GCAAAAATAT CCACGTAGCA ACAGCTCATG AAGATTTGGC CTACTCTTCT 
TATGTCCACC AGTATAGCTC TGGGAAATTT GACAATGCAC TATTTCATGC AGAAAGAGCT 
ATTGGTATCA TTACCCACAT CCTACCTGAA GATCATCTTC TTTTGGCTTC TTCAAAGAGG 
GTGAAAGCAC TTATTTTAGA GGAGATTGCA ATTGATTGTC ATAATAAGGA AACTGAACAG 
AGGCTGCTTC AAGAAGCTCA TGATTTGCAC CTGTCTTCAC TCCAACTAGC TAAAAAAGCT 
TTTGGGGAAT TTAATGTACA GACTGCAAAA CACTATGGAA ACCTTGGAAG ACTTTATCAG 
TCAATGAGAA AATTTAAGGA AGCTGAAGAA ATGCACATCA AAGCAATTCA GATTAAAGAA 
CAACTTCTTG GTCAAGAAGA TTATGAAGTA GCCCTTTCAG TGGGACATCT GGCTTCTTTA 
TATAATTATG ACATGAATCA GTATGAAAAT GCTGAGAAAC TTTATTTGCG ATCTATAGCA 
ATTGGGAAGA AACTTTTTGG TGAGGGCTAC AGTGGACTAG AATATGATTA TCGAGGTCTC 
ATTAAACTTT ACAACTCCAT TGGAAATTAC GAGAAAGTGT TTGAATATCA CAATGTTCTG 
TCTAACTGGA ACCGGTTGCG AGATCGGCAA TATTCAGTGA CAGATGCTCT TGAAGATGTC 
AGCACCAGCC CCCAGTCCAC TGAAGAAGTG GTGCAGTCCT TCCTGATTTC TCAGAATGTC 
GAGGGACCGA GCTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APPBP2 ( XM_011524198.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011522500.1 Homo sapiens amyloid beta precursor protein binding protein 2 (APPBP2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu64078
Clone ID Related Accession (Same CDS sequence)	XM_011524198.2 , XM_011524198.3
Accession Version	XM_011524198.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1500bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	amyloid protein-binding protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011524198.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATCATG GTGTTAAAGT TGCTTCAGTC TTGGCCTACT CATTCAGTAG GCGGTGCTCT 
TATATAGCAG AATCAGATGC TGCAGTAAAG GAAAAAGCCA TTCAGGTTGG CTTTGTTTTA 
GGTGGCTTTC TTTCAGATGC AGGCTGGTAC AGTGATGCTG AGAAAGTTTT TCTGTCCTGC 
CTTCAGTTGT GTACTCTACA CGATGAGATG CTTCATTGGT TTCGTGCAGT AGAATGTTGT 
GTGAGGTTGC TTCATGTGCG AAATGGAAAC TGCAAATATC ATTTGGGTGA AGAAACATTT 
AAATTAGCTC AGACATATAT GGATAAACTA TCAAAACATG GCCAGCAAGC AAATAAAGCT 
GCACTCTATG GAGAACTGTG TGCACTCCTA TTTGCAAAAA GTCACTATGA TGAGGCATAC 
AAATGGTGCA TCGAGGCAAT GAAAGAAATT ACAGCAGGCT TACCAGTGAA AGTTGTGGTG 
GATGTCTTAA GACAAGCTTC TAAGGCTTGT GTAGTAAAAC GTGAATTTAA GAAGGCAGAA 
CAGTTAATTA AACATGCAGT GTATTTGGCA CGGGATCATT TTGGATCCAA ACACCCAAAA 
TATTCTGATA CACTGCTAGA TTATGGGTTC TACTTACTCA ATGTAGATAA TATCTGTCAG 
TCTGTTGCAA TTTATCAGGC AGCCCTTGAC ATTAGACAGT CAGTGTTTGG TGGCAAAAAT 
ATCCACGTAG CAACAGCTCA TGAAGATTTG GCCTACTCTT CTTATGTCCA CCAGTATAGC 
TCTGGGAAAT TTGACAATGC ACTATTTCAT GCAGAAAGAG CTATTGGTAT CATTACCCAC 
ATCCTACCTG AAGATCATCT TCTTTTGGCT TCTTCAAAGA GGGTGAAAGC ACTTATTTTA 
GAGGAGATTG CAATTGATTG TCATAATAAG GAAACTGAAC AGAGGCTGCT TCAAGAAGCT 
CATGATTTGC ACCTGTCTTC ACTCCAACTA GCTAAAAAAG CTTTTGGGGA ATTTAATGTA 
CAGACTGCAA AACACTATGG AAACCTTGGA AGACTTTATC AGTCAATGAG AAAATTTAAG 
GAAGCTGAAG AAATGCACAT CAAAGCAATT CAGATTAAAG AACAACTTCT TGGTCAAGAA 
GATTATGAAG TAGCCCTTTC AGTGGGACAT CTGGCTTCTT TATATAATTA TGACATGAAT 
CAGTATGAAA ATGCTGAGAA ACTTTATTTG CGATCTATAG CAATTGGGAA GAAACTTTTT 
GGTGAGGGCT ACAGTGGACT AGAATATGAT TATCGAGGTC TCATTAAACT TTACAACTCC 
ATTGGAAATT ACGAGAAAGT GTTTGAATAT CACAATGTTC TGTCTAACTG GAACCGGTTG 
CGAGATCGGC AATATTCAGT GACAGATGCT CTTGAAGATG TCAGCACCAG CCCCCAGTCC 
ACTGAAGAAG TGGTGCAGTC CTTCCTGATT TCTCAGAATG TCGAGGGACC GAGCTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011522500.1
CDS	295..1794
Translation	MDHGVKVASVLAYSFSRRCSYIAESDAAVKEKAIQVGFVLGGFLSDAGWYSDAEKVFLSCLQLCTLHDEMLHWFRAVECCVRLLHVRNGNCKYHLGEETFKLAQTYMDKLSKHGQQANKAALYGELCALLFAKSHYDEAYKWCIEAMKEITAGLPVKVVVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLNVDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEKVFEYHNVLSNWNRLRDRQYSVTDALEDVSTSPQSTEEVVQSFLISQNVEGPSC

Target ORF information:

RefSeq Version	XM_011524198.2
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor protein binding protein 2 (APPBP2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011524198.2

ORF Insert Sequence:

ATGGATCATG GTGTTAAAGT TGCTTCAGTC TTGGCCTACT CATTCAGTAG GCGGTGCTCT 
TATATAGCAG AATCAGATGC TGCAGTAAAG GAAAAAGCCA TTCAGGTTGG CTTTGTTTTA 
GGTGGCTTTC TTTCAGATGC AGGCTGGTAC AGTGATGCTG AGAAAGTTTT TCTGTCCTGC 
CTTCAGTTGT GTACTCTACA CGATGAGATG CTTCATTGGT TTCGTGCAGT AGAATGTTGT 
GTGAGGTTGC TTCATGTGCG AAATGGAAAC TGCAAATATC ATTTGGGTGA AGAAACATTT 
AAATTAGCTC AGACATATAT GGATAAACTA TCAAAACATG GCCAGCAAGC AAATAAAGCT 
GCACTCTATG GAGAACTGTG TGCACTCCTA TTTGCAAAAA GTCACTATGA TGAGGCATAC 
AAATGGTGCA TCGAGGCAAT GAAAGAAATT ACAGCAGGCT TACCAGTGAA AGTTGTGGTG 
GATGTCTTAA GACAAGCTTC TAAGGCTTGT GTAGTAAAAC GTGAATTTAA GAAGGCAGAA 
CAGTTAATTA AACATGCAGT GTATTTGGCA CGGGATCATT TTGGATCCAA ACACCCAAAA 
TATTCTGATA CACTGCTAGA TTATGGGTTC TACTTACTCA ATGTAGATAA TATCTGTCAG 
TCTGTTGCAA TTTATCAGGC AGCCCTTGAC ATTAGACAGT CAGTGTTTGG TGGCAAAAAT 
ATCCACGTAG CAACAGCTCA TGAAGATTTG GCCTACTCTT CTTATGTCCA CCAGTATAGC 
TCTGGGAAAT TTGACAATGC ACTATTTCAT GCAGAAAGAG CTATTGGTAT CATTACCCAC 
ATCCTACCTG AAGATCATCT TCTTTTGGCT TCTTCAAAGA GGGTGAAAGC ACTTATTTTA 
GAGGAGATTG CAATTGATTG TCATAATAAG GAAACTGAAC AGAGGCTGCT TCAAGAAGCT 
CATGATTTGC ACCTGTCTTC ACTCCAACTA GCTAAAAAAG CTTTTGGGGA ATTTAATGTA 
CAGACTGCAA AACACTATGG AAACCTTGGA AGACTTTATC AGTCAATGAG AAAATTTAAG 
GAAGCTGAAG AAATGCACAT CAAAGCAATT CAGATTAAAG AACAACTTCT TGGTCAAGAA 
GATTATGAAG TAGCCCTTTC AGTGGGACAT CTGGCTTCTT TATATAATTA TGACATGAAT 
CAGTATGAAA ATGCTGAGAA ACTTTATTTG CGATCTATAG CAATTGGGAA GAAACTTTTT 
GGTGAGGGCT ACAGTGGACT AGAATATGAT TATCGAGGTC TCATTAAACT TTACAACTCC 
ATTGGAAATT ACGAGAAAGT GTTTGAATAT CACAATGTTC TGTCTAACTG GAACCGGTTG 
CGAGATCGGC AATATTCAGT GACAGATGCT CTTGAAGATG TCAGCACCAG CCCCCAGTCC 
ACTGAAGAAG TGGTGCAGTC CTTCCTGATT TCTCAGAATG TCGAGGGACC GAGCTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APPBP2 ( XM_011524198.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011522500.1 Homo sapiens amyloid beta precursor protein binding protein 2 (APPBP2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu64078
Clone ID Related Accession (Same CDS sequence)	XM_011524198.2 , XM_011524198.3
Accession Version	XM_011524198.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1500bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	amyloid protein-binding protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011524198.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATCATG GTGTTAAAGT TGCTTCAGTC TTGGCCTACT CATTCAGTAG GCGGTGCTCT 
TATATAGCAG AATCAGATGC TGCAGTAAAG GAAAAAGCCA TTCAGGTTGG CTTTGTTTTA 
GGTGGCTTTC TTTCAGATGC AGGCTGGTAC AGTGATGCTG AGAAAGTTTT TCTGTCCTGC 
CTTCAGTTGT GTACTCTACA CGATGAGATG CTTCATTGGT TTCGTGCAGT AGAATGTTGT 
GTGAGGTTGC TTCATGTGCG AAATGGAAAC TGCAAATATC ATTTGGGTGA AGAAACATTT 
AAATTAGCTC AGACATATAT GGATAAACTA TCAAAACATG GCCAGCAAGC AAATAAAGCT 
GCACTCTATG GAGAACTGTG TGCACTCCTA TTTGCAAAAA GTCACTATGA TGAGGCATAC 
AAATGGTGCA TCGAGGCAAT GAAAGAAATT ACAGCAGGCT TACCAGTGAA AGTTGTGGTG 
GATGTCTTAA GACAAGCTTC TAAGGCTTGT GTAGTAAAAC GTGAATTTAA GAAGGCAGAA 
CAGTTAATTA AACATGCAGT GTATTTGGCA CGGGATCATT TTGGATCCAA ACACCCAAAA 
TATTCTGATA CACTGCTAGA TTATGGGTTC TACTTACTCA ATGTAGATAA TATCTGTCAG 
TCTGTTGCAA TTTATCAGGC AGCCCTTGAC ATTAGACAGT CAGTGTTTGG TGGCAAAAAT 
ATCCACGTAG CAACAGCTCA TGAAGATTTG GCCTACTCTT CTTATGTCCA CCAGTATAGC 
TCTGGGAAAT TTGACAATGC ACTATTTCAT GCAGAAAGAG CTATTGGTAT CATTACCCAC 
ATCCTACCTG AAGATCATCT TCTTTTGGCT TCTTCAAAGA GGGTGAAAGC ACTTATTTTA 
GAGGAGATTG CAATTGATTG TCATAATAAG GAAACTGAAC AGAGGCTGCT TCAAGAAGCT 
CATGATTTGC ACCTGTCTTC ACTCCAACTA GCTAAAAAAG CTTTTGGGGA ATTTAATGTA 
CAGACTGCAA AACACTATGG AAACCTTGGA AGACTTTATC AGTCAATGAG AAAATTTAAG 
GAAGCTGAAG AAATGCACAT CAAAGCAATT CAGATTAAAG AACAACTTCT TGGTCAAGAA 
GATTATGAAG TAGCCCTTTC AGTGGGACAT CTGGCTTCTT TATATAATTA TGACATGAAT 
CAGTATGAAA ATGCTGAGAA ACTTTATTTG CGATCTATAG CAATTGGGAA GAAACTTTTT 
GGTGAGGGCT ACAGTGGACT AGAATATGAT TATCGAGGTC TCATTAAACT TTACAACTCC 
ATTGGAAATT ACGAGAAAGT GTTTGAATAT CACAATGTTC TGTCTAACTG GAACCGGTTG 
CGAGATCGGC AATATTCAGT GACAGATGCT CTTGAAGATG TCAGCACCAG CCCCCAGTCC 
ACTGAAGAAG TGGTGCAGTC CTTCCTGATT TCTCAGAATG TCGAGGGACC GAGCTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011522500.1
CDS	295..1794
Translation	MDHGVKVASVLAYSFSRRCSYIAESDAAVKEKAIQVGFVLGGFLSDAGWYSDAEKVFLSCLQLCTLHDEMLHWFRAVECCVRLLHVRNGNCKYHLGEETFKLAQTYMDKLSKHGQQANKAALYGELCALLFAKSHYDEAYKWCIEAMKEITAGLPVKVVVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLNVDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEKVFEYHNVLSNWNRLRDRQYSVTDALEDVSTSPQSTEEVVQSFLISQNVEGPSC

Target ORF information:

RefSeq Version	XM_011524198.3
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor protein binding protein 2 (APPBP2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011524198.3

ORF Insert Sequence:

ATGGATCATG GTGTTAAAGT TGCTTCAGTC TTGGCCTACT CATTCAGTAG GCGGTGCTCT 
TATATAGCAG AATCAGATGC TGCAGTAAAG GAAAAAGCCA TTCAGGTTGG CTTTGTTTTA 
GGTGGCTTTC TTTCAGATGC AGGCTGGTAC AGTGATGCTG AGAAAGTTTT TCTGTCCTGC 
CTTCAGTTGT GTACTCTACA CGATGAGATG CTTCATTGGT TTCGTGCAGT AGAATGTTGT 
GTGAGGTTGC TTCATGTGCG AAATGGAAAC TGCAAATATC ATTTGGGTGA AGAAACATTT 
AAATTAGCTC AGACATATAT GGATAAACTA TCAAAACATG GCCAGCAAGC AAATAAAGCT 
GCACTCTATG GAGAACTGTG TGCACTCCTA TTTGCAAAAA GTCACTATGA TGAGGCATAC 
AAATGGTGCA TCGAGGCAAT GAAAGAAATT ACAGCAGGCT TACCAGTGAA AGTTGTGGTG 
GATGTCTTAA GACAAGCTTC TAAGGCTTGT GTAGTAAAAC GTGAATTTAA GAAGGCAGAA 
CAGTTAATTA AACATGCAGT GTATTTGGCA CGGGATCATT TTGGATCCAA ACACCCAAAA 
TATTCTGATA CACTGCTAGA TTATGGGTTC TACTTACTCA ATGTAGATAA TATCTGTCAG 
TCTGTTGCAA TTTATCAGGC AGCCCTTGAC ATTAGACAGT CAGTGTTTGG TGGCAAAAAT 
ATCCACGTAG CAACAGCTCA TGAAGATTTG GCCTACTCTT CTTATGTCCA CCAGTATAGC 
TCTGGGAAAT TTGACAATGC ACTATTTCAT GCAGAAAGAG CTATTGGTAT CATTACCCAC 
ATCCTACCTG AAGATCATCT TCTTTTGGCT TCTTCAAAGA GGGTGAAAGC ACTTATTTTA 
GAGGAGATTG CAATTGATTG TCATAATAAG GAAACTGAAC AGAGGCTGCT TCAAGAAGCT 
CATGATTTGC ACCTGTCTTC ACTCCAACTA GCTAAAAAAG CTTTTGGGGA ATTTAATGTA 
CAGACTGCAA AACACTATGG AAACCTTGGA AGACTTTATC AGTCAATGAG AAAATTTAAG 
GAAGCTGAAG AAATGCACAT CAAAGCAATT CAGATTAAAG AACAACTTCT TGGTCAAGAA 
GATTATGAAG TAGCCCTTTC AGTGGGACAT CTGGCTTCTT TATATAATTA TGACATGAAT 
CAGTATGAAA ATGCTGAGAA ACTTTATTTG CGATCTATAG CAATTGGGAA GAAACTTTTT 
GGTGAGGGCT ACAGTGGACT AGAATATGAT TATCGAGGTC TCATTAAACT TTACAACTCC 
ATTGGAAATT ACGAGAAAGT GTTTGAATAT CACAATGTTC TGTCTAACTG GAACCGGTTG 
CGAGATCGGC AATATTCAGT GACAGATGCT CTTGAAGATG TCAGCACCAG CCCCCAGTCC 
ACTGAAGAAG TGGTGCAGTC CTTCCTGATT TCTCAGAATG TCGAGGGACC GAGCTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APPBP2 ( XM_011524199.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011522501.1 Homo sapiens amyloid beta precursor protein binding protein 2 (APPBP2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu64079
Clone ID Related Accession (Same CDS sequence)	XM_011524199.2
Accession Version	XM_011524199.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1182bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	amyloid protein-binding protein 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011524199.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATAAAC TATCAAAACA TGGCCAGCAA GCAAATAAAG CTGCACTCTA TGGAGAACTG 
TGTGCACTCC TATTTGCAAA AAGTCACTAT GATGAGGCAT ACAAATGGTG CATCGAGGCA 
ATGAAAGAAA TTACAGCAGG CTTACCAGTG AAAGTTGTGG TGGATGTCTT AAGACAAGCT 
TCTAAGGCTT GTGTAGTAAA ACGTGAATTT AAGAAGGCAG AACAGTTAAT TAAACATGCA 
GTGTATTTGG CACGGGATCA TTTTGGATCC AAACACCCAA AATATTCTGA TACACTGCTA 
GATTATGGGT TCTACTTACT CAATGTAGAT AATATCTGTC AGTCTGTTGC AATTTATCAG 
GCAGCCCTTG ACATTAGACA GTCAGTGTTT GGTGGCAAAA ATATCCACGT AGCAACAGCT 
CATGAAGATT TGGCCTACTC TTCTTATGTC CACCAGTATA GCTCTGGGAA ATTTGACAAT 
GCACTATTTC ATGCAGAAAG AGCTATTGGT ATCATTACCC ACATCCTACC TGAAGATCAT 
CTTCTTTTGG CTTCTTCAAA GAGGGTGAAA GCACTTATTT TAGAGGAGAT TGCAATTGAT 
TGTCATAATA AGGAAACTGA ACAGAGGCTG CTTCAAGAAG CTCATGATTT GCACCTGTCT 
TCACTCCAAC TAGCTAAAAA AGCTTTTGGG GAATTTAATG TACAGACTGC AAAACACTAT 
GGAAACCTTG GAAGACTTTA TCAGTCAATG AGAAAATTTA AGGAAGCTGA AGAAATGCAC 
ATCAAAGCAA TTCAGATTAA AGAACAACTT CTTGGTCAAG AAGATTATGA AGTAGCCCTT 
TCAGTGGGAC ATCTGGCTTC TTTATATAAT TATGACATGA ATCAGTATGA AAATGCTGAG 
AAACTTTATT TGCGATCTAT AGCAATTGGG AAGAAACTTT TTGGTGAGGG CTACAGTGGA 
CTAGAATATG ATTATCGAGG TCTCATTAAA CTTTACAACT CCATTGGAAA TTACGAGAAA 
GTGTTTGAAT ATCACAATGT TCTGTCTAAC TGGAACCGGT TGCGAGATCG GCAATATTCA 
GTGACAGATG CTCTTGAAGA TGTCAGCACC AGCCCCCAGT CCACTGAAGA AGTGGTGCAG 
TCCTTCCTGA TTTCTCAGAA TGTCGAGGGA CCGAGCTGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011522501.1
CDS	98..1279
Translation	MDKLSKHGQQANKAALYGELCALLFAKSHYDEAYKWCIEAMKEITAGLPVKVVVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLNVDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEKVFEYHNVLSNWNRLRDRQYSVTDALEDVSTSPQSTEEVVQSFLISQNVEGPSC

Target ORF information:

RefSeq Version	XM_011524199.2
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor protein binding protein 2 (APPBP2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011524199.2

ORF Insert Sequence:

ATGGATAAAC TATCAAAACA TGGCCAGCAA GCAAATAAAG CTGCACTCTA TGGAGAACTG 
TGTGCACTCC TATTTGCAAA AAGTCACTAT GATGAGGCAT ACAAATGGTG CATCGAGGCA 
ATGAAAGAAA TTACAGCAGG CTTACCAGTG AAAGTTGTGG TGGATGTCTT AAGACAAGCT 
TCTAAGGCTT GTGTAGTAAA ACGTGAATTT AAGAAGGCAG AACAGTTAAT TAAACATGCA 
GTGTATTTGG CACGGGATCA TTTTGGATCC AAACACCCAA AATATTCTGA TACACTGCTA 
GATTATGGGT TCTACTTACT CAATGTAGAT AATATCTGTC AGTCTGTTGC AATTTATCAG 
GCAGCCCTTG ACATTAGACA GTCAGTGTTT GGTGGCAAAA ATATCCACGT AGCAACAGCT 
CATGAAGATT TGGCCTACTC TTCTTATGTC CACCAGTATA GCTCTGGGAA ATTTGACAAT 
GCACTATTTC ATGCAGAAAG AGCTATTGGT ATCATTACCC ACATCCTACC TGAAGATCAT 
CTTCTTTTGG CTTCTTCAAA GAGGGTGAAA GCACTTATTT TAGAGGAGAT TGCAATTGAT 
TGTCATAATA AGGAAACTGA ACAGAGGCTG CTTCAAGAAG CTCATGATTT GCACCTGTCT 
TCACTCCAAC TAGCTAAAAA AGCTTTTGGG GAATTTAATG TACAGACTGC AAAACACTAT 
GGAAACCTTG GAAGACTTTA TCAGTCAATG AGAAAATTTA AGGAAGCTGA AGAAATGCAC 
ATCAAAGCAA TTCAGATTAA AGAACAACTT CTTGGTCAAG AAGATTATGA AGTAGCCCTT 
TCAGTGGGAC ATCTGGCTTC TTTATATAAT TATGACATGA ATCAGTATGA AAATGCTGAG 
AAACTTTATT TGCGATCTAT AGCAATTGGG AAGAAACTTT TTGGTGAGGG CTACAGTGGA 
CTAGAATATG ATTATCGAGG TCTCATTAAA CTTTACAACT CCATTGGAAA TTACGAGAAA 
GTGTTTGAAT ATCACAATGT TCTGTCTAAC TGGAACCGGT TGCGAGATCG GCAATATTCA 
GTGACAGATG CTCTTGAAGA TGTCAGCACC AGCCCCCAGT CCACTGAAGA AGTGGTGCAG 
TCCTTCCTGA TTTCTCAGAA TGTCGAGGGA CCGAGCTGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APPBP2 ( NM_001282476.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269405.1 Homo sapiens amyloid beta precursor protein binding protein 2 (APPBP2), transcript variant 2, mRNA.

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CloneID	OHu08252
Clone ID Related Accession (Same CDS sequence)	NM_001282476.1
Accession Version	NM_001282476.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1545bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-07
Organism	Homo sapiens(human)
Product	amyloid protein-binding protein 2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP222365.1, D86981.1 and AC037475.9. Transcript Variant: This variant (2) lacks an in-frame exon in the 5' coding region, compared to variant (1). The encoded isoform (2) is shorter, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.57639.1, AK307666.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTTACTA CAAGACATTT GCTTCATCAT TGTTTTCAGG CTTTGATGGA TCATGGTGTT 
AAAGTTGCTT CAGTCTTGGC CTACTCATTC AGTAGGCGGT GCTCTTATAT AGCAGAATCA 
GATGCTGCAG TAAAGGAAAA AGCCATTCAG GTTGGCTTTG TTTTAGGTGG CTTTCTTTCA 
GATGCAGGCT GGTACAGTGA TGCTGAGAAA GTTTTTCTGT CCTGCCTTCA GTTGTGTACT 
CTACACGATG AGATGCTTCA TTGGTTTCGT GCAGTAGAAT GTTGTGTGAG GTTGCTTCAT 
GTGCGAAATG GAAACTGCAA ATATCATTTG GGTGAAGAAA CATTTAAATT AGCTCAGACA 
TATATGGATA AACTATCAAA ACATGGCCAG CAAGCAAATA AAGCTGCACT CTATGGAGAA 
CTGTGTGCAC TCCTATTTGC AAAAAGTCAC TATGATGAGG CATACAAATG GTGCATCGAG 
GCAATGAAAG AAATTACAGC AGGCTTACCA GTGAAAGTTG TGGTGGATGT CTTAAGACAA 
GCTTCTAAGG CTTGTGTAGT AAAACGTGAA TTTAAGAAGG CAGAACAGTT AATTAAACAT 
GCAGTGTATT TGGCACGGGA TCATTTTGGA TCCAAACACC CAAAATATTC TGATACACTG 
CTAGATTATG GGTTCTACTT ACTCAATGTA GATAATATCT GTCAGTCTGT TGCAATTTAT 
CAGGCAGCCC TTGACATTAG ACAGTCAGTG TTTGGTGGCA AAAATATCCA CGTAGCAACA 
GCTCATGAAG ATTTGGCCTA CTCTTCTTAT GTCCACCAGT ATAGCTCTGG GAAATTTGAC 
AATGCACTAT TTCATGCAGA AAGAGCTATT GGTATCATTA CCCACATCCT ACCTGAAGAT 
CATCTTCTTT TGGCTTCTTC AAAGAGGGTG AAAGCACTTA TTTTAGAGGA GATTGCAATT 
GATTGTCATA ATAAGGAAAC TGAACAGAGG CTGCTTCAAG AAGCTCATGA TTTGCACCTG 
TCTTCACTCC AACTAGCTAA AAAAGCTTTT GGGGAATTTA ATGTACAGAC TGCAAAACAC 
TATGGAAACC TTGGAAGACT TTATCAGTCA ATGAGAAAAT TTAAGGAAGC TGAAGAAATG 
CACATCAAAG CAATTCAGAT TAAAGAACAA CTTCTTGGTC AAGAAGATTA TGAAGTAGCC 
CTTTCAGTGG GACATCTGGC TTCTTTATAT AATTATGACA TGAATCAGTA TGAAAATGCT 
GAGAAACTTT ATTTGCGATC TATAGCAATT GGGAAGAAAC TTTTTGGTGA GGGCTACAGT 
GGACTAGAAT ATGATTATCG AGGTCTCATT AAACTTTACA ACTCCATTGG AAATTACGAG 
AAAGTGTTTG AATATCACAA TGTTCTGTCT AACTGGAACC GGTTGCGAGA TCGGCAATAT 
TCAGTGACAG ATGCTCTTGA AGATGTCAGC ACCAGCCCCC AGTCCACTGA AGAAGTGGTG 
CAGTCCTTCC TGATTTCTCA GAATGTCGAG GGACCGAGCT GCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269405.1
CDS	434..1978
Translation	MFTTRHLLHHCFQALMDHGVKVASVLAYSFSRRCSYIAESDAAVKEKAIQVGFVLGGFLSDAGWYSDAEKVFLSCLQLCTLHDEMLHWFRAVECCVRLLHVRNGNCKYHLGEETFKLAQTYMDKLSKHGQQANKAALYGELCALLFAKSHYDEAYKWCIEAMKEITAGLPVKVVVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLNVDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEKVFEYHNVLSNWNRLRDRQYSVTDALEDVSTSPQSTEEVVQSFLISQNVEGPSC

Target ORF information:

RefSeq Version	NM_001282476.1
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor protein binding protein 2 (APPBP2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282476.1

ORF Insert Sequence:

ATGTTTACTA CAAGACATTT GCTTCATCAT TGTTTTCAGG CTTTGATGGA TCATGGTGTT 
AAAGTTGCTT CAGTCTTGGC CTACTCATTC AGTAGGCGGT GCTCTTATAT AGCAGAATCA 
GATGCTGCAG TAAAGGAAAA AGCCATTCAG GTTGGCTTTG TTTTAGGTGG CTTTCTTTCA 
GATGCAGGCT GGTACAGTGA TGCTGAGAAA GTTTTTCTGT CCTGCCTTCA GTTGTGTACT 
CTACACGATG AGATGCTTCA TTGGTTTCGT GCAGTAGAAT GTTGTGTGAG GTTGCTTCAT 
GTGCGAAATG GAAACTGCAA ATATCATTTG GGTGAAGAAA CATTTAAATT AGCTCAGACA 
TATATGGATA AACTATCAAA ACATGGCCAG CAAGCAAATA AAGCTGCACT CTATGGAGAA 
CTGTGTGCAC TCCTATTTGC AAAAAGTCAC TATGATGAGG CATACAAATG GTGCATCGAG 
GCAATGAAAG AAATTACAGC AGGCTTACCA GTGAAAGTTG TGGTGGATGT CTTAAGACAA 
GCTTCTAAGG CTTGTGTAGT AAAACGTGAA TTTAAGAAGG CAGAACAGTT AATTAAACAT 
GCAGTGTATT TGGCACGGGA TCATTTTGGA TCCAAACACC CAAAATATTC TGATACACTG 
CTAGATTATG GGTTCTACTT ACTCAATGTA GATAATATCT GTCAGTCTGT TGCAATTTAT 
CAGGCAGCCC TTGACATTAG ACAGTCAGTG TTTGGTGGCA AAAATATCCA CGTAGCAACA 
GCTCATGAAG ATTTGGCCTA CTCTTCTTAT GTCCACCAGT ATAGCTCTGG GAAATTTGAC 
AATGCACTAT TTCATGCAGA AAGAGCTATT GGTATCATTA CCCACATCCT ACCTGAAGAT 
CATCTTCTTT TGGCTTCTTC AAAGAGGGTG AAAGCACTTA TTTTAGAGGA GATTGCAATT 
GATTGTCATA ATAAGGAAAC TGAACAGAGG CTGCTTCAAG AAGCTCATGA TTTGCACCTG 
TCTTCACTCC AACTAGCTAA AAAAGCTTTT GGGGAATTTA ATGTACAGAC TGCAAAACAC 
TATGGAAACC TTGGAAGACT TTATCAGTCA ATGAGAAAAT TTAAGGAAGC TGAAGAAATG 
CACATCAAAG CAATTCAGAT TAAAGAACAA CTTCTTGGTC AAGAAGATTA TGAAGTAGCC 
CTTTCAGTGG GACATCTGGC TTCTTTATAT AATTATGACA TGAATCAGTA TGAAAATGCT 
GAGAAACTTT ATTTGCGATC TATAGCAATT GGGAAGAAAC TTTTTGGTGA GGGCTACAGT 
GGACTAGAAT ATGATTATCG AGGTCTCATT AAACTTTACA ACTCCATTGG AAATTACGAG 
AAAGTGTTTG AATATCACAA TGTTCTGTCT AACTGGAACC GGTTGCGAGA TCGGCAATAT 
TCAGTGACAG ATGCTCTTGA AGATGTCAGC ACCAGCCCCC AGTCCACTGA AGAAGTGGTG 
CAGTCCTTCC TGATTTCTCA GAATGTCGAG GGACCGAGCT GCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.
Science signaling8(371)rs3(2015 Apr)
So J,Pasculescu A,Dai AY,Williton K,James A,Nguyen V,Creixell P,Schoof EM,Sinclair J,Barrios-Rodiles M,Gu J,Krizus A,Williams R,Olhovsky M,Dennis JW,Wrana JL,Linding R,Jorgensen C,Pawson T,Colwill K

Amyloid-? precursor protein facilitates the regulator of calcineurin 1-mediated apoptosis by downregulating proteasome subunit ? type-5 and proteasome subunit ? type-7.
Neurobiology of aging36(1)169-77(2015 Jan)
Wu Y,Deng Y,Zhang S,Luo Y,Cai F,Zhang Z,Zhou W,Li T,Song W

PAT1 induces cell death signal and SET mislocalization into the cytoplasm by increasing APP/APLP2 at the cell surface.
Neurobiology of aging32(6)1099-113(2011 Jun)
Briand S,Facchinetti P,Clamagirand C,Madeira A,Pommet JM,Pimplikar SW,Allinquant B

Pat1 proteins: a life in translation, translation repression and mRNA decay.
Biochemical Society transactions38(6)1602-7(2010 Dec)
Marnef A,Standart N

Association of the herpes simplex virus type 1 Us11 gene product with the cellular kinesin light-chain-related protein PAT1 results in the redistribution of both polypeptides.
Journal of virology77(17)9192-203(2003 Sep)
Benboudjema L,Mulvey M,Gao Y,Pimplikar SW,Mohr I

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APPBP2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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