TOMM40 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TOMM40
Entrez Gene ID	10452
Full Name	translocase of outer mitochondrial membrane 40
Synonyms	C19orf1,D19S1177E,PER-EC1,PEREC1,TOM40
General protein information	Preferred Names translocase of outer mitochondrial membrane 40 Names mitochondrial import receptor subunit TOM40 homolog mitochondrial outer membrane protein p38.5 protein Haymaker translocase of outer membrane 40 kDa subunit homolog translocase of outer mitochondrial membrane 40 homolog
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.32
Summary	The protein encoded by this gene is localized in the outer membrane of the mitochondria. It is the channel-forming subunit of the translocase of the mitochondrial outer membrane (TOM) complex that is essential for import of protein precursors into mitochondria. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2015].
Disorder MIM:	608061

mRNA and Protein(s)

mRNA	Protein	Name
XM_005258411.3	XP_005258468.1	mitochondrial import receptor subunit TOM40 homolog isoform X1
NM_001128917.1	NP_001122389.1	mitochondrial import receptor subunit TOM40 homolog
NM_001128917.2	NP_001122389.1	mitochondrial import receptor subunit TOM40 homolog
NM_001128916.1	NP_001122388.1	mitochondrial import receptor subunit TOM40 homolog
XM_005258411.4	XP_005258468.1	mitochondrial import receptor subunit TOM40 homolog isoform X1
NM_006114.2	NP_006105.1	mitochondrial import receptor subunit TOM40 homolog
NM_006114.3	NP_006105.1	mitochondrial import receptor subunit TOM40 homolog

Pathways from BioSystems

Homologies

Drosophila melanogaster (fruit fly)	tomboy40	NP_610213.1
Saccharomyces cerevisiae (baker's yeast)	TOM40	NP_013930.1
	TOMM40	XP_001109661.1
Drosophila melanogaster (fruit fly)	Tom40	NP_001259313.1
Caenorhabditis elegans (roundworm)	tomm-40	NP_495912.1
Kluyveromyces lactis	KLLA0F06292g	XP_455365.1
Eremothecium gossypii	AGOS_AFL183C	NP_985367.1
Xenopus tropicalis (tropical clawed frog)	tomm40	NP_989125.1
Homo sapiens (human)	TOMM40	NP_006105.1
Bos taurus (cattle)	TOMM40	NP_001068906.1
Rattus norvegicus (Norway rat)	Tomm40	NP_997685.1
Danio rerio (zebrafish)	tomm40	NP_955908.1
Schizosaccharomyces pombe (fission yeast)	tom40	NP_595546.2
Arabidopsis thaliana (thale cress)	AT1G50400	NP_175457.1
Canis lupus familiaris (dog)	TOMM40	XP_852633.1
Magnaporthe oryzae (rice blast fungus)	MGG_08637	XP_003711067.1
Neurospora crassa	NCU01179	XP_961545.1
Mus musculus (house mouse)	Tomm40	NP_001103218.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007871	XP_317621.2

Gene Ontology
Bibliography

Related articles in PubMed

Neuropathologic features of TOMM40 '523 variant on late-life cognitive decline.
Yu L, Lutz MW, Farfel JM, Wilson RS, Burns DK, Saunders AM, De Jager PL, Barnes LL, Schneider JA, Bennett DA
Alzheimer's & dementia : the journal of the Alzheimer's Association13(12)1380-1388(2017 Dec)

The biological foundation of the genetic association of TOMM40 with late-onset Alzheimer's disease.
Zeitlow K, Charlambous L, Ng I, Gagrani S, Mihovilovic M, Luo S, Rock DL, Saunders A, Roses AD, Gottschalk WK
Biochimica et biophysica acta1863(11)2973-2986(2017 Nov)

Family history and TOMM40 '523 interactive associations with memory in middle-aged and Alzheimer's disease cohorts.
Willette AA, Webb JL, Lutz MW, Bendlin BB, Wennberg AM, Oh JM, Roses A, Koscik RL, Hermann BP, Dowling NM, Asthana S, Johnson SC,
Alzheimer's & dementia : the journal of the Alzheimer's Association13(11)1217-1225(2017 Nov)

APOE ?4-TOMM40 '523 haplotypes and the risk of Alzheimer's disease in older Caucasian and African Americans.
Yu L, Lutz MW, Wilson RS, Burns DK, Roses AD, Saunders AM, Yang J, Gaiteri C, De Jager PL, Barnes LL, Bennett DA
PloS one12(7)e0180356(2017)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Among white women, three single nucleotide polymorphisms (SNPs) (rs2075650 [TOMM40], rs4420638 [APOC1], and rs429358 [APOE]) were significantly associated with survival to 90 years after correction for multiple testing (p < .001); rs4420638 and rs429358 were also significantly associated with healthy aging (p = .02). In African American women, no SNP was associated with longevity. In Hispanic women, 7 SNPs in linkage dise
Title: Replication of Genome-Wide Association Study Findings of Longevity in White, African American, and Hispanic Women: The Women's Health Initiative.

Our data provide support for TOMM40 variant repeat length as an important contributor to AD-like Medial Temporal Lobe pathology in the absence of APOE epsilon4.
Title: Hippocampal thinning linked to longer TOMM40 poly-T variant lengths in the absence of the APOE ?4 variant.

report association of APOE and TOMM40 with behavioural variant frontotemporal dementia, and ARHGAP35 and SERPINA1 with progressive non-fluent aphasia.
Title: Gene-based association studies report genetic links for clinical subtypes of frontotemporal dementia.

Results reveal an association of APOE epsilon3/3-TOMM40'523 haplotypes with cognitive decline in community-based older persons such that the S/S poly-T genotype is related to faster cognitive decline, primarily in the domains of episodic and semantic memory.

Each epsilon4 allele doubled the risk for AD dementia and the dose effect was evident. Almost identical effect size and effect pattern were observed for TOMM40 '523-L
Title: APOE ?4-TOMM40 '523 haplotypes and the risk of Alzheimer's disease in older Caucasian and African Americans.

The following TOMM40 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TOMM40 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu16384	NM_001128916.1 Latest version!	Homo sapiens translocase of outer mitochondrial membrane 40 (TOMM40), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$149.50-$209.30 $299.00
OHu16384	NM_006114.3 Latest version!	Homo sapiens translocase of outer mitochondrial membrane 40 (TOMM40), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$149.50-$209.30 $299.00
OHu16384	NM_001128917.2 Latest version!	Homo sapiens translocase of outer mitochondrial membrane 40 (TOMM40), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$149.50-$209.30 $299.00
OHu51947	XM_005258411.4 Latest version!	Homo sapiens translocase of outer mitochondrial membrane 40 (TOMM40), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
View Old Accession Versions >>
OHu16384	NM_001128917.1	Homo sapiens translocase of outer mitochondrial membrane 40 (TOMM40), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$149.50-$209.30 $299.00
OHu51947	XM_005258411.3	Homo sapiens translocase of outer mitochondrial membrane 40 (TOMM40), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
OHu16384	NM_006114.2	Homo sapiens translocase of outer mitochondrial membrane 40 (TOMM40), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$149.50-$209.30 $299.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TOMM40 ( NM_001128917.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001122389.1 Homo sapiens translocase of outer mitochondrial membrane 40 (TOMM40), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu16384
Clone ID Related Accession (Same CDS sequence)	NM_001128917.1 , NM_001128917.2 , NM_001128916.1 , NM_006114.2 , NM_006114.3
Accession Version	NM_001128917.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1086bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-28
Organism	Homo sapiens(human)
Product	mitochondrial import receptor subunit TOM40 homolog
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP265648.1, BC001779.1 and BC017224.2. This sequence is a reference standard in the RefSeqGene project. Transcript Variant: This variant (1) represents the longest transcript. Variants 1-3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC017224.2, SRR1163658.312031.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGGAACG TGTTGGCTGC CAGCTCGCCG CCCGCAGGGC CGCCACCGCC GCCTGCGCCG 
GCCCTCGTGG GGCTGCCGCC ACCTCCGCCC TCGCCGCCGG GCTTCACGCT GCCGCCGCTG 
GGAGGCAGCC TGGGCGCCGG CACCAGTACG AGTCGAAGTT CGGAACGGAC CCCCGGGGCT 
GCAACCGCCA GCGCCTCAGG GGCCGCCGAG GATGGGGCCT GCGGCTGCCT GCCCAACCCG 
GGCACATTCG AGGAGTGCCA CCGGAAGTGC AAGGAGCTGT TTCCCATTCA GATGGAGGGT 
GTCAAGCTCA CAGTCAACAA AGGGTTGAGT AACCATTTTC AGGTCAACCA CACAGTAGCC 
CTCAGCACAA TCGGGGAGTC CAACTACCAC TTCGGGGTCA CATATGTGGG GACAAAGCAG 
CTGAGTCCCA CAGAGGCGTT CCCTGTACTG GTGGGTGACA TGGACAACAG TGGCAGTCTC 
AACGCTCAGG TCATTCACCA GCTGGGCCCC GGTCTCAGGT CCAAGATGGC CATCCAGACC 
CAGCAGTCGA AGTTTGTGAA CTGGCAGGTG GACGGGGAGT ATCGGGGCTC TGACTTCACA 
GCAGCCGTCA CCCTGGGGAA CCCAGACGTC CTCGTGGGTT CAGGAATCCT CGTAGCCCAC 
TACCTCCAGA GCATCACGCC TTGCCTGGCC CTGGGTGGAG AGCTGGTCTA CCACCGGCGG 
CCTGGAGAGG AGGGCACTGT CATGTCTCTA GCTGGGAAAT ACACATTGAA CAACTGGTTG 
GCAACGGTAA CGTTGGGCCA GGCGGGCATG CACGCAACAT ACTACCACAA AGCCAGTGAC 
CAGCTGCAGG TGGGTGTGGA GTTTGAGGCC AGCACAAGGA TGCAGGACAC CAGCGTCTCC 
TTCGGGTACC AGCTGGACCT GCCCAAGGCC AACCTCCTCT TCAAAGGCTC TGTGGATAGC 
AACTGGATCG TGGGTGCCAC GCTGGAGAAG AAGCTCCCAC CCCTGCCCCT GACACTGGCC 
CTTGGGGCCT TCCTGAATCA CCGCAAGAAC AAGTTTCAGT GTGGCTTTGG CCTCACCATC 
GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001122389.1
CDS	197..1282
Translation	MGNVLAASSPPAGPPPPPAPALVGLPPPPPSPPGFTLPPLGGSLGAGTSTSRSSERTPGAATASASGAAEDGACGCLPNPGTFEECHRKCKELFPIQMEGVKLTVNKGLSNHFQVNHTVALSTIGESNYHFGVTYVGTKQLSPTEAFPVLVGDMDNSGSLNAQVIHQLGPGLRSKMAIQTQQSKFVNWQVDGEYRGSDFTAAVTLGNPDVLVGSGILVAHYLQSITPCLALGGELVYHRRPGEEGTVMSLAGKYTLNNWLATVTLGQAGMHATYYHKASDQLQVGVEFEASTRMQDTSVSFGYQLDLPKANLLFKGSVDSNWIVGATLEKKLPPLPLTLALGAFLNHRKNKFQCGFGLTIG

Target ORF information:

RefSeq Version	NM_001128917.1
Organism	Homo sapiens(human)
Definition	Homo sapiens translocase of outer mitochondrial membrane 40 (TOMM40), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001128917.1

ORF Insert Sequence:

ATGGGGAACG TGTTGGCTGC CAGCTCGCCG CCCGCAGGGC CGCCACCGCC GCCTGCGCCG 
GCCCTCGTGG GGCTGCCGCC ACCTCCGCCC TCGCCGCCGG GCTTCACGCT GCCGCCGCTG 
GGAGGCAGCC TGGGCGCCGG CACCAGTACG AGTCGAAGTT CGGAACGGAC CCCCGGGGCT 
GCAACCGCCA GCGCCTCAGG GGCCGCCGAG GATGGGGCCT GCGGCTGCCT GCCCAACCCG 
GGCACATTCG AGGAGTGCCA CCGGAAGTGC AAGGAGCTGT TTCCCATTCA GATGGAGGGT 
GTCAAGCTCA CAGTCAACAA AGGGTTGAGT AACCATTTTC AGGTCAACCA CACAGTAGCC 
CTCAGCACAA TCGGGGAGTC CAACTACCAC TTCGGGGTCA CATATGTGGG GACAAAGCAG 
CTGAGTCCCA CAGAGGCGTT CCCTGTACTG GTGGGTGACA TGGACAACAG TGGCAGTCTC 
AACGCTCAGG TCATTCACCA GCTGGGCCCC GGTCTCAGGT CCAAGATGGC CATCCAGACC 
CAGCAGTCGA AGTTTGTGAA CTGGCAGGTG GACGGGGAGT ATCGGGGCTC TGACTTCACA 
GCAGCCGTCA CCCTGGGGAA CCCAGACGTC CTCGTGGGTT CAGGAATCCT CGTAGCCCAC 
TACCTCCAGA GCATCACGCC TTGCCTGGCC CTGGGTGGAG AGCTGGTCTA CCACCGGCGG 
CCTGGAGAGG AGGGCACTGT CATGTCTCTA GCTGGGAAAT ACACATTGAA CAACTGGTTG 
GCAACGGTAA CGTTGGGCCA GGCGGGCATG CACGCAACAT ACTACCACAA AGCCAGTGAC 
CAGCTGCAGG TGGGTGTGGA GTTTGAGGCC AGCACAAGGA TGCAGGACAC CAGCGTCTCC 
TTCGGGTACC AGCTGGACCT GCCCAAGGCC AACCTCCTCT TCAAAGGCTC TGTGGATAGC 
AACTGGATCG TGGGTGCCAC GCTGGAGAAG AAGCTCCCAC CCCTGCCCCT GACACTGGCC 
CTTGGGGCCT TCCTGAATCA CCGCAAGAAC AAGTTTCAGT GTGGCTTTGG CCTCACCATC 
GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TOMM40 ( NM_001128917.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001122389.1 Homo sapiens translocase of outer mitochondrial membrane 40 (TOMM40), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu16384
Clone ID Related Accession (Same CDS sequence)	NM_001128917.1 , NM_001128917.2 , NM_001128916.1 , NM_006114.2 , NM_006114.3
Accession Version	NM_001128917.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1086bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-21
Organism	Homo sapiens(human)
Product	mitochondrial import receptor subunit TOM40 homolog
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP265648.1, BC001779.1 and BC017224.2. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_001128917.1. Transcript Variant: This variant (1) represents the longest transcript. Variants 1-3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC017224.2, SRR1163658.312031.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta MANE Ensembl match :: ENST00000426677.7/ ENSP00000410339.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGGAACG TGTTGGCTGC CAGCTCGCCG CCCGCAGGGC CGCCACCGCC GCCTGCGCCG 
GCCCTCGTGG GGCTGCCGCC ACCTCCGCCC TCGCCGCCGG GCTTCACGCT GCCGCCGCTG 
GGAGGCAGCC TGGGCGCCGG CACCAGTACG AGTCGAAGTT CGGAACGGAC CCCCGGGGCT 
GCAACCGCCA GCGCCTCAGG GGCCGCCGAG GATGGGGCCT GCGGCTGCCT GCCCAACCCG 
GGCACATTCG AGGAGTGCCA CCGGAAGTGC AAGGAGCTGT TTCCCATTCA GATGGAGGGT 
GTCAAGCTCA CAGTCAACAA AGGGTTGAGT AACCATTTTC AGGTCAACCA CACAGTAGCC 
CTCAGCACAA TCGGGGAGTC CAACTACCAC TTCGGGGTCA CATATGTGGG GACAAAGCAG 
CTGAGTCCCA CAGAGGCGTT CCCTGTACTG GTGGGTGACA TGGACAACAG TGGCAGTCTC 
AACGCTCAGG TCATTCACCA GCTGGGCCCC GGTCTCAGGT CCAAGATGGC CATCCAGACC 
CAGCAGTCGA AGTTTGTGAA CTGGCAGGTG GACGGGGAGT ATCGGGGCTC TGACTTCACA 
GCAGCCGTCA CCCTGGGGAA CCCAGACGTC CTCGTGGGTT CAGGAATCCT CGTAGCCCAC 
TACCTCCAGA GCATCACGCC TTGCCTGGCC CTGGGTGGAG AGCTGGTCTA CCACCGGCGG 
CCTGGAGAGG AGGGCACTGT CATGTCTCTA GCTGGGAAAT ACACATTGAA CAACTGGTTG 
GCAACGGTAA CGTTGGGCCA GGCGGGCATG CACGCAACAT ACTACCACAA AGCCAGTGAC 
CAGCTGCAGG TGGGTGTGGA GTTTGAGGCC AGCACAAGGA TGCAGGACAC CAGCGTCTCC 
TTCGGGTACC AGCTGGACCT GCCCAAGGCC AACCTCCTCT TCAAAGGCTC TGTGGATAGC 
AACTGGATCG TGGGTGCCAC GCTGGAGAAG AAGCTCCCAC CCCTGCCCCT GACACTGGCC 
CTTGGGGCCT TCCTGAATCA CCGCAAGAAC AAGTTTCAGT GTGGCTTTGG CCTCACCATC 
GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001122389.1
CDS	163..1248
Translation	MGNVLAASSPPAGPPPPPAPALVGLPPPPPSPPGFTLPPLGGSLGAGTSTSRSSERTPGAATASASGAAEDGACGCLPNPGTFEECHRKCKELFPIQMEGVKLTVNKGLSNHFQVNHTVALSTIGESNYHFGVTYVGTKQLSPTEAFPVLVGDMDNSGSLNAQVIHQLGPGLRSKMAIQTQQSKFVNWQVDGEYRGSDFTAAVTLGNPDVLVGSGILVAHYLQSITPCLALGGELVYHRRPGEEGTVMSLAGKYTLNNWLATVTLGQAGMHATYYHKASDQLQVGVEFEASTRMQDTSVSFGYQLDLPKANLLFKGSVDSNWIVGATLEKKLPPLPLTLALGAFLNHRKNKFQCGFGLTIG

Target ORF information:

RefSeq Version	NM_001128917.2
Organism	Homo sapiens(human)
Definition	Homo sapiens translocase of outer mitochondrial membrane 40 (TOMM40), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001128917.2

ORF Insert Sequence:

ATGGGGAACG TGTTGGCTGC CAGCTCGCCG CCCGCAGGGC CGCCACCGCC GCCTGCGCCG 
GCCCTCGTGG GGCTGCCGCC ACCTCCGCCC TCGCCGCCGG GCTTCACGCT GCCGCCGCTG 
GGAGGCAGCC TGGGCGCCGG CACCAGTACG AGTCGAAGTT CGGAACGGAC CCCCGGGGCT 
GCAACCGCCA GCGCCTCAGG GGCCGCCGAG GATGGGGCCT GCGGCTGCCT GCCCAACCCG 
GGCACATTCG AGGAGTGCCA CCGGAAGTGC AAGGAGCTGT TTCCCATTCA GATGGAGGGT 
GTCAAGCTCA CAGTCAACAA AGGGTTGAGT AACCATTTTC AGGTCAACCA CACAGTAGCC 
CTCAGCACAA TCGGGGAGTC CAACTACCAC TTCGGGGTCA CATATGTGGG GACAAAGCAG 
CTGAGTCCCA CAGAGGCGTT CCCTGTACTG GTGGGTGACA TGGACAACAG TGGCAGTCTC 
AACGCTCAGG TCATTCACCA GCTGGGCCCC GGTCTCAGGT CCAAGATGGC CATCCAGACC 
CAGCAGTCGA AGTTTGTGAA CTGGCAGGTG GACGGGGAGT ATCGGGGCTC TGACTTCACA 
GCAGCCGTCA CCCTGGGGAA CCCAGACGTC CTCGTGGGTT CAGGAATCCT CGTAGCCCAC 
TACCTCCAGA GCATCACGCC TTGCCTGGCC CTGGGTGGAG AGCTGGTCTA CCACCGGCGG 
CCTGGAGAGG AGGGCACTGT CATGTCTCTA GCTGGGAAAT ACACATTGAA CAACTGGTTG 
GCAACGGTAA CGTTGGGCCA GGCGGGCATG CACGCAACAT ACTACCACAA AGCCAGTGAC 
CAGCTGCAGG TGGGTGTGGA GTTTGAGGCC AGCACAAGGA TGCAGGACAC CAGCGTCTCC 
TTCGGGTACC AGCTGGACCT GCCCAAGGCC AACCTCCTCT TCAAAGGCTC TGTGGATAGC 
AACTGGATCG TGGGTGCCAC GCTGGAGAAG AAGCTCCCAC CCCTGCCCCT GACACTGGCC 
CTTGGGGCCT TCCTGAATCA CCGCAAGAAC AAGTTTCAGT GTGGCTTTGG CCTCACCATC 
GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TOMM40 ( NM_001128916.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001122388.1 Homo sapiens translocase of outer mitochondrial membrane 40 (TOMM40), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu16384
Clone ID Related Accession (Same CDS sequence)	NM_001128917.1 , NM_001128917.2 , NM_001128916.1 , NM_006114.2 , NM_006114.3
Accession Version	NM_001128916.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1086bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-03
Organism	Homo sapiens(human)
Product	mitochondrial import receptor subunit TOM40 homolog
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP265648.1, BC012134.1 and BC017224.2. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1-3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.244274.1, SRR1163657.139642.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGGAACG TGTTGGCTGC CAGCTCGCCG CCCGCAGGGC CGCCACCGCC GCCTGCGCCG 
GCCCTCGTGG GGCTGCCGCC ACCTCCGCCC TCGCCGCCGG GCTTCACGCT GCCGCCGCTG 
GGAGGCAGCC TGGGCGCCGG CACCAGTACG AGTCGAAGTT CGGAACGGAC CCCCGGGGCT 
GCAACCGCCA GCGCCTCAGG GGCCGCCGAG GATGGGGCCT GCGGCTGCCT GCCCAACCCG 
GGCACATTCG AGGAGTGCCA CCGGAAGTGC AAGGAGCTGT TTCCCATTCA GATGGAGGGT 
GTCAAGCTCA CAGTCAACAA AGGGTTGAGT AACCATTTTC AGGTCAACCA CACAGTAGCC 
CTCAGCACAA TCGGGGAGTC CAACTACCAC TTCGGGGTCA CATATGTGGG GACAAAGCAG 
CTGAGTCCCA CAGAGGCGTT CCCTGTACTG GTGGGTGACA TGGACAACAG TGGCAGTCTC 
AACGCTCAGG TCATTCACCA GCTGGGCCCC GGTCTCAGGT CCAAGATGGC CATCCAGACC 
CAGCAGTCGA AGTTTGTGAA CTGGCAGGTG GACGGGGAGT ATCGGGGCTC TGACTTCACA 
GCAGCCGTCA CCCTGGGGAA CCCAGACGTC CTCGTGGGTT CAGGAATCCT CGTAGCCCAC 
TACCTCCAGA GCATCACGCC TTGCCTGGCC CTGGGTGGAG AGCTGGTCTA CCACCGGCGG 
CCTGGAGAGG AGGGCACTGT CATGTCTCTA GCTGGGAAAT ACACATTGAA CAACTGGTTG 
GCAACGGTAA CGTTGGGCCA GGCGGGCATG CACGCAACAT ACTACCACAA AGCCAGTGAC 
CAGCTGCAGG TGGGTGTGGA GTTTGAGGCC AGCACAAGGA TGCAGGACAC CAGCGTCTCC 
TTCGGGTACC AGCTGGACCT GCCCAAGGCC AACCTCCTCT TCAAAGGCTC TGTGGATAGC 
AACTGGATCG TGGGTGCCAC GCTGGAGAAG AAGCTCCCAC CCCTGCCCCT GACACTGGCC 
CTTGGGGCCT TCCTGAATCA CCGCAAGAAC AAGTTTCAGT GTGGCTTTGG CCTCACCATC 
GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001122388.1
CDS	105..1190
Translation	MGNVLAASSPPAGPPPPPAPALVGLPPPPPSPPGFTLPPLGGSLGAGTSTSRSSERTPGAATASASGAAEDGACGCLPNPGTFEECHRKCKELFPIQMEGVKLTVNKGLSNHFQVNHTVALSTIGESNYHFGVTYVGTKQLSPTEAFPVLVGDMDNSGSLNAQVIHQLGPGLRSKMAIQTQQSKFVNWQVDGEYRGSDFTAAVTLGNPDVLVGSGILVAHYLQSITPCLALGGELVYHRRPGEEGTVMSLAGKYTLNNWLATVTLGQAGMHATYYHKASDQLQVGVEFEASTRMQDTSVSFGYQLDLPKANLLFKGSVDSNWIVGATLEKKLPPLPLTLALGAFLNHRKNKFQCGFGLTIG

Target ORF information:

RefSeq Version	NM_001128916.1
Organism	Homo sapiens(human)
Definition	Homo sapiens translocase of outer mitochondrial membrane 40 (TOMM40), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001128916.1

ORF Insert Sequence:

ATGGGGAACG TGTTGGCTGC CAGCTCGCCG CCCGCAGGGC CGCCACCGCC GCCTGCGCCG 
GCCCTCGTGG GGCTGCCGCC ACCTCCGCCC TCGCCGCCGG GCTTCACGCT GCCGCCGCTG 
GGAGGCAGCC TGGGCGCCGG CACCAGTACG AGTCGAAGTT CGGAACGGAC CCCCGGGGCT 
GCAACCGCCA GCGCCTCAGG GGCCGCCGAG GATGGGGCCT GCGGCTGCCT GCCCAACCCG 
GGCACATTCG AGGAGTGCCA CCGGAAGTGC AAGGAGCTGT TTCCCATTCA GATGGAGGGT 
GTCAAGCTCA CAGTCAACAA AGGGTTGAGT AACCATTTTC AGGTCAACCA CACAGTAGCC 
CTCAGCACAA TCGGGGAGTC CAACTACCAC TTCGGGGTCA CATATGTGGG GACAAAGCAG 
CTGAGTCCCA CAGAGGCGTT CCCTGTACTG GTGGGTGACA TGGACAACAG TGGCAGTCTC 
AACGCTCAGG TCATTCACCA GCTGGGCCCC GGTCTCAGGT CCAAGATGGC CATCCAGACC 
CAGCAGTCGA AGTTTGTGAA CTGGCAGGTG GACGGGGAGT ATCGGGGCTC TGACTTCACA 
GCAGCCGTCA CCCTGGGGAA CCCAGACGTC CTCGTGGGTT CAGGAATCCT CGTAGCCCAC 
TACCTCCAGA GCATCACGCC TTGCCTGGCC CTGGGTGGAG AGCTGGTCTA CCACCGGCGG 
CCTGGAGAGG AGGGCACTGT CATGTCTCTA GCTGGGAAAT ACACATTGAA CAACTGGTTG 
GCAACGGTAA CGTTGGGCCA GGCGGGCATG CACGCAACAT ACTACCACAA AGCCAGTGAC 
CAGCTGCAGG TGGGTGTGGA GTTTGAGGCC AGCACAAGGA TGCAGGACAC CAGCGTCTCC 
TTCGGGTACC AGCTGGACCT GCCCAAGGCC AACCTCCTCT TCAAAGGCTC TGTGGATAGC 
AACTGGATCG TGGGTGCCAC GCTGGAGAAG AAGCTCCCAC CCCTGCCCCT GACACTGGCC 
CTTGGGGCCT TCCTGAATCA CCGCAAGAAC AAGTTTCAGT GTGGCTTTGG CCTCACCATC 
GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TOMM40 ( NM_006114.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_006105.1 Homo sapiens translocase of outer mitochondrial membrane 40 (TOMM40), transcript variant 3, mRNA.

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CloneID	OHu16384
Clone ID Related Accession (Same CDS sequence)	NM_001128917.1 , NM_001128917.2 , NM_001128916.1 , NM_006114.2 , NM_006114.3
Accession Version	NM_006114.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1086bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-17
Organism	Homo sapiens(human)
Product	mitochondrial import receptor subunit TOM40 homolog
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP265648.1, AF043250.1 and BC017224.2. On Jun 27, 2008 this sequence version replaced NM_006114.1. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1-3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF043250.1, SRR1163655.412049.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGGAACG TGTTGGCTGC CAGCTCGCCG CCCGCAGGGC CGCCACCGCC GCCTGCGCCG 
GCCCTCGTGG GGCTGCCGCC ACCTCCGCCC TCGCCGCCGG GCTTCACGCT GCCGCCGCTG 
GGAGGCAGCC TGGGCGCCGG CACCAGTACG AGTCGAAGTT CGGAACGGAC CCCCGGGGCT 
GCAACCGCCA GCGCCTCAGG GGCCGCCGAG GATGGGGCCT GCGGCTGCCT GCCCAACCCG 
GGCACATTCG AGGAGTGCCA CCGGAAGTGC AAGGAGCTGT TTCCCATTCA GATGGAGGGT 
GTCAAGCTCA CAGTCAACAA AGGGTTGAGT AACCATTTTC AGGTCAACCA CACAGTAGCC 
CTCAGCACAA TCGGGGAGTC CAACTACCAC TTCGGGGTCA CATATGTGGG GACAAAGCAG 
CTGAGTCCCA CAGAGGCGTT CCCTGTACTG GTGGGTGACA TGGACAACAG TGGCAGTCTC 
AACGCTCAGG TCATTCACCA GCTGGGCCCC GGTCTCAGGT CCAAGATGGC CATCCAGACC 
CAGCAGTCGA AGTTTGTGAA CTGGCAGGTG GACGGGGAGT ATCGGGGCTC TGACTTCACA 
GCAGCCGTCA CCCTGGGGAA CCCAGACGTC CTCGTGGGTT CAGGAATCCT CGTAGCCCAC 
TACCTCCAGA GCATCACGCC TTGCCTGGCC CTGGGTGGAG AGCTGGTCTA CCACCGGCGG 
CCTGGAGAGG AGGGCACTGT CATGTCTCTA GCTGGGAAAT ACACATTGAA CAACTGGTTG 
GCAACGGTAA CGTTGGGCCA GGCGGGCATG CACGCAACAT ACTACCACAA AGCCAGTGAC 
CAGCTGCAGG TGGGTGTGGA GTTTGAGGCC AGCACAAGGA TGCAGGACAC CAGCGTCTCC 
TTCGGGTACC AGCTGGACCT GCCCAAGGCC AACCTCCTCT TCAAAGGCTC TGTGGATAGC 
AACTGGATCG TGGGTGCCAC GCTGGAGAAG AAGCTCCCAC CCCTGCCCCT GACACTGGCC 
CTTGGGGCCT TCCTGAATCA CCGCAAGAAC AAGTTTCAGT GTGGCTTTGG CCTCACCATC 
GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006105.1
CDS	102..1187
Translation	MGNVLAASSPPAGPPPPPAPALVGLPPPPPSPPGFTLPPLGGSLGAGTSTSRSSERTPGAATASASGAAEDGACGCLPNPGTFEECHRKCKELFPIQMEGVKLTVNKGLSNHFQVNHTVALSTIGESNYHFGVTYVGTKQLSPTEAFPVLVGDMDNSGSLNAQVIHQLGPGLRSKMAIQTQQSKFVNWQVDGEYRGSDFTAAVTLGNPDVLVGSGILVAHYLQSITPCLALGGELVYHRRPGEEGTVMSLAGKYTLNNWLATVTLGQAGMHATYYHKASDQLQVGVEFEASTRMQDTSVSFGYQLDLPKANLLFKGSVDSNWIVGATLEKKLPPLPLTLALGAFLNHRKNKFQCGFGLTIG

Target ORF information:

RefSeq Version	NM_006114.2
Organism	Homo sapiens(human)
Definition	Homo sapiens translocase of outer mitochondrial membrane 40 (TOMM40), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006114.2

ORF Insert Sequence:

ATGGGGAACG TGTTGGCTGC CAGCTCGCCG CCCGCAGGGC CGCCACCGCC GCCTGCGCCG 
GCCCTCGTGG GGCTGCCGCC ACCTCCGCCC TCGCCGCCGG GCTTCACGCT GCCGCCGCTG 
GGAGGCAGCC TGGGCGCCGG CACCAGTACG AGTCGAAGTT CGGAACGGAC CCCCGGGGCT 
GCAACCGCCA GCGCCTCAGG GGCCGCCGAG GATGGGGCCT GCGGCTGCCT GCCCAACCCG 
GGCACATTCG AGGAGTGCCA CCGGAAGTGC AAGGAGCTGT TTCCCATTCA GATGGAGGGT 
GTCAAGCTCA CAGTCAACAA AGGGTTGAGT AACCATTTTC AGGTCAACCA CACAGTAGCC 
CTCAGCACAA TCGGGGAGTC CAACTACCAC TTCGGGGTCA CATATGTGGG GACAAAGCAG 
CTGAGTCCCA CAGAGGCGTT CCCTGTACTG GTGGGTGACA TGGACAACAG TGGCAGTCTC 
AACGCTCAGG TCATTCACCA GCTGGGCCCC GGTCTCAGGT CCAAGATGGC CATCCAGACC 
CAGCAGTCGA AGTTTGTGAA CTGGCAGGTG GACGGGGAGT ATCGGGGCTC TGACTTCACA 
GCAGCCGTCA CCCTGGGGAA CCCAGACGTC CTCGTGGGTT CAGGAATCCT CGTAGCCCAC 
TACCTCCAGA GCATCACGCC TTGCCTGGCC CTGGGTGGAG AGCTGGTCTA CCACCGGCGG 
CCTGGAGAGG AGGGCACTGT CATGTCTCTA GCTGGGAAAT ACACATTGAA CAACTGGTTG 
GCAACGGTAA CGTTGGGCCA GGCGGGCATG CACGCAACAT ACTACCACAA AGCCAGTGAC 
CAGCTGCAGG TGGGTGTGGA GTTTGAGGCC AGCACAAGGA TGCAGGACAC CAGCGTCTCC 
TTCGGGTACC AGCTGGACCT GCCCAAGGCC AACCTCCTCT TCAAAGGCTC TGTGGATAGC 
AACTGGATCG TGGGTGCCAC GCTGGAGAAG AAGCTCCCAC CCCTGCCCCT GACACTGGCC 
CTTGGGGCCT TCCTGAATCA CCGCAAGAAC AAGTTTCAGT GTGGCTTTGG CCTCACCATC 
GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TOMM40 ( NM_006114.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_006105.1 Homo sapiens translocase of outer mitochondrial membrane 40 (TOMM40), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu16384
Clone ID Related Accession (Same CDS sequence)	NM_001128917.1 , NM_001128917.2 , NM_001128916.1 , NM_006114.2 , NM_006114.3
Accession Version	NM_006114.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1086bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	mitochondrial import receptor subunit TOM40 homolog
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF043250.1 and BC017224.2. On May 31, 2019 this sequence version replaced NM_006114.2. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1-3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF043250.1, SRR1163658.473247.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGGAACG TGTTGGCTGC CAGCTCGCCG CCCGCAGGGC CGCCACCGCC GCCTGCGCCG 
GCCCTCGTGG GGCTGCCGCC ACCTCCGCCC TCGCCGCCGG GCTTCACGCT GCCGCCGCTG 
GGAGGCAGCC TGGGCGCCGG CACCAGTACG AGTCGAAGTT CGGAACGGAC CCCCGGGGCT 
GCAACCGCCA GCGCCTCAGG GGCCGCCGAG GATGGGGCCT GCGGCTGCCT GCCCAACCCG 
GGCACATTCG AGGAGTGCCA CCGGAAGTGC AAGGAGCTGT TTCCCATTCA GATGGAGGGT 
GTCAAGCTCA CAGTCAACAA AGGGTTGAGT AACCATTTTC AGGTCAACCA CACAGTAGCC 
CTCAGCACAA TCGGGGAGTC CAACTACCAC TTCGGGGTCA CATATGTGGG GACAAAGCAG 
CTGAGTCCCA CAGAGGCGTT CCCTGTACTG GTGGGTGACA TGGACAACAG TGGCAGTCTC 
AACGCTCAGG TCATTCACCA GCTGGGCCCC GGTCTCAGGT CCAAGATGGC CATCCAGACC 
CAGCAGTCGA AGTTTGTGAA CTGGCAGGTG GACGGGGAGT ATCGGGGCTC TGACTTCACA 
GCAGCCGTCA CCCTGGGGAA CCCAGACGTC CTCGTGGGTT CAGGAATCCT CGTAGCCCAC 
TACCTCCAGA GCATCACGCC TTGCCTGGCC CTGGGTGGAG AGCTGGTCTA CCACCGGCGG 
CCTGGAGAGG AGGGCACTGT CATGTCTCTA GCTGGGAAAT ACACATTGAA CAACTGGTTG 
GCAACGGTAA CGTTGGGCCA GGCGGGCATG CACGCAACAT ACTACCACAA AGCCAGTGAC 
CAGCTGCAGG TGGGTGTGGA GTTTGAGGCC AGCACAAGGA TGCAGGACAC CAGCGTCTCC 
TTCGGGTACC AGCTGGACCT GCCCAAGGCC AACCTCCTCT TCAAAGGCTC TGTGGATAGC 
AACTGGATCG TGGGTGCCAC GCTGGAGAAG AAGCTCCCAC CCCTGCCCCT GACACTGGCC 
CTTGGGGCCT TCCTGAATCA CCGCAAGAAC AAGTTTCAGT GTGGCTTTGG CCTCACCATC 
GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006105.1
CDS	68..1153
Translation	MGNVLAASSPPAGPPPPPAPALVGLPPPPPSPPGFTLPPLGGSLGAGTSTSRSSERTPGAATASASGAAEDGACGCLPNPGTFEECHRKCKELFPIQMEGVKLTVNKGLSNHFQVNHTVALSTIGESNYHFGVTYVGTKQLSPTEAFPVLVGDMDNSGSLNAQVIHQLGPGLRSKMAIQTQQSKFVNWQVDGEYRGSDFTAAVTLGNPDVLVGSGILVAHYLQSITPCLALGGELVYHRRPGEEGTVMSLAGKYTLNNWLATVTLGQAGMHATYYHKASDQLQVGVEFEASTRMQDTSVSFGYQLDLPKANLLFKGSVDSNWIVGATLEKKLPPLPLTLALGAFLNHRKNKFQCGFGLTIG

Target ORF information:

RefSeq Version	NM_006114.3
Organism	Homo sapiens(human)
Definition	Homo sapiens translocase of outer mitochondrial membrane 40 (TOMM40), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006114.3

ORF Insert Sequence:

ATGGGGAACG TGTTGGCTGC CAGCTCGCCG CCCGCAGGGC CGCCACCGCC GCCTGCGCCG 
GCCCTCGTGG GGCTGCCGCC ACCTCCGCCC TCGCCGCCGG GCTTCACGCT GCCGCCGCTG 
GGAGGCAGCC TGGGCGCCGG CACCAGTACG AGTCGAAGTT CGGAACGGAC CCCCGGGGCT 
GCAACCGCCA GCGCCTCAGG GGCCGCCGAG GATGGGGCCT GCGGCTGCCT GCCCAACCCG 
GGCACATTCG AGGAGTGCCA CCGGAAGTGC AAGGAGCTGT TTCCCATTCA GATGGAGGGT 
GTCAAGCTCA CAGTCAACAA AGGGTTGAGT AACCATTTTC AGGTCAACCA CACAGTAGCC 
CTCAGCACAA TCGGGGAGTC CAACTACCAC TTCGGGGTCA CATATGTGGG GACAAAGCAG 
CTGAGTCCCA CAGAGGCGTT CCCTGTACTG GTGGGTGACA TGGACAACAG TGGCAGTCTC 
AACGCTCAGG TCATTCACCA GCTGGGCCCC GGTCTCAGGT CCAAGATGGC CATCCAGACC 
CAGCAGTCGA AGTTTGTGAA CTGGCAGGTG GACGGGGAGT ATCGGGGCTC TGACTTCACA 
GCAGCCGTCA CCCTGGGGAA CCCAGACGTC CTCGTGGGTT CAGGAATCCT CGTAGCCCAC 
TACCTCCAGA GCATCACGCC TTGCCTGGCC CTGGGTGGAG AGCTGGTCTA CCACCGGCGG 
CCTGGAGAGG AGGGCACTGT CATGTCTCTA GCTGGGAAAT ACACATTGAA CAACTGGTTG 
GCAACGGTAA CGTTGGGCCA GGCGGGCATG CACGCAACAT ACTACCACAA AGCCAGTGAC 
CAGCTGCAGG TGGGTGTGGA GTTTGAGGCC AGCACAAGGA TGCAGGACAC CAGCGTCTCC 
TTCGGGTACC AGCTGGACCT GCCCAAGGCC AACCTCCTCT TCAAAGGCTC TGTGGATAGC 
AACTGGATCG TGGGTGCCAC GCTGGAGAAG AAGCTCCCAC CCCTGCCCCT GACACTGGCC 
CTTGGGGCCT TCCTGAATCA CCGCAAGAAC AAGTTTCAGT GTGGCTTTGG CCTCACCATC 
GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TOMM40 ( XM_005258411.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005258468.1 Homo sapiens translocase of outer mitochondrial membrane 40 (TOMM40), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu51947
Clone ID Related Accession (Same CDS sequence)	XM_005258411.3 , XM_005258411.4
Accession Version	XM_005258411.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1008bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	mitochondrial import receptor subunit TOM40 homolog isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005258411.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGAACG TGTTGGCTGC CAGCTCGCCG CCCGCAGGGC CGCCACCGCC GCCTGCGCCG 
GCCCTCGTGG GGCTGCCGCC ACCTCCGCCC TCGCCGCCGG GCTTCACGCT GCCGCCGCTG 
GGAGGCAGCC TGGGCGCCGG CACCAGTACG AGTCGAAGTT CGGAACGGAC CCCCGGGGCT 
GCAACCGCCA GCGCCTCAGG GGCCGCCGAG GATGGGGCCT GCGGCTGCCT GCCCAACCCG 
GGCACATTCG AGGAGTGCCA CCGGAAGTGC AAGGAGCTGT TTCCCATTCA GATGGAGGGT 
GTCAAGCTCA CAGTCAACAA AGGGTTGAGT AACCATTTTC AGGTCAACCA CACAGTAGCC 
CTCAGCACAA TCGGGGAGTC CAACTACCAC TTCGGGGTCA CATATGTGGG GACAAAGCAG 
CTGAGTCCCA CAGAGGCGTT CCCTGTACTG GTGGGTGACA TGGACAACAG TGGCAGTCTC 
AACGCTCAGG TCATTCACCA GCTGGGCCCC GGTCTCAGGT CCAAGATGGC CATCCAGACC 
CAGCAGTCGA AGTTTGTGAA CTGGCAGGTG GACGGGGAGT ATCGGGGCTC TGACTTCACA 
GCAGCCGTCA CCCTGGGGAA CCCAGACGTC CTCGTGGGTT CAGGAATCCT CGTAGCCCAC 
TACCTCCAGA GCATCACGCC TTGCCTGGCC CTGGGTGGAG AGCTGGTCTA CCACCGGCGG 
CCTGGAGAGG AGGGCACTGT CATGTCTCTA GCTGGGAAAT ACACATTGAA CAACTGGTTG 
GCAACGGTAA CGTTGGGCCA GGCGGGCATG CACGCAACAT ACTACCACAA AGCCAGTGAC 
CAGCTGCAGG TGGGTGTGGA GTTTGAGGCC AGCACAAGGA TGCAGGACAC CAGCGTCTCC 
TTCGGGTACC AGCTGGACCT GCCCAAGGCC AACCTCCTCT TCAAAGGTGC TGGAGGACAG 
TGTGCTGCCA CCCTGTGGGC CTCCACATTA CCAGGGAACA CTTGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005258468.1
CDS	99..1106
Translation	MGNVLAASSPPAGPPPPPAPALVGLPPPPPSPPGFTLPPLGGSLGAGTSTSRSSERTPGAATASASGAAEDGACGCLPNPGTFEECHRKCKELFPIQMEGVKLTVNKGLSNHFQVNHTVALSTIGESNYHFGVTYVGTKQLSPTEAFPVLVGDMDNSGSLNAQVIHQLGPGLRSKMAIQTQQSKFVNWQVDGEYRGSDFTAAVTLGNPDVLVGSGILVAHYLQSITPCLALGGELVYHRRPGEEGTVMSLAGKYTLNNWLATVTLGQAGMHATYYHKASDQLQVGVEFEASTRMQDTSVSFGYQLDLPKANLLFKGAGGQCAATLWASTLPGNTC

Target ORF information:

RefSeq Version	XM_005258411.3
Organism	Homo sapiens(human)
Definition	Homo sapiens translocase of outer mitochondrial membrane 40 (TOMM40), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005258411.3

ORF Insert Sequence:

ATGGGGAACG TGTTGGCTGC CAGCTCGCCG CCCGCAGGGC CGCCACCGCC GCCTGCGCCG 
GCCCTCGTGG GGCTGCCGCC ACCTCCGCCC TCGCCGCCGG GCTTCACGCT GCCGCCGCTG 
GGAGGCAGCC TGGGCGCCGG CACCAGTACG AGTCGAAGTT CGGAACGGAC CCCCGGGGCT 
GCAACCGCCA GCGCCTCAGG GGCCGCCGAG GATGGGGCCT GCGGCTGCCT GCCCAACCCG 
GGCACATTCG AGGAGTGCCA CCGGAAGTGC AAGGAGCTGT TTCCCATTCA GATGGAGGGT 
GTCAAGCTCA CAGTCAACAA AGGGTTGAGT AACCATTTTC AGGTCAACCA CACAGTAGCC 
CTCAGCACAA TCGGGGAGTC CAACTACCAC TTCGGGGTCA CATATGTGGG GACAAAGCAG 
CTGAGTCCCA CAGAGGCGTT CCCTGTACTG GTGGGTGACA TGGACAACAG TGGCAGTCTC 
AACGCTCAGG TCATTCACCA GCTGGGCCCC GGTCTCAGGT CCAAGATGGC CATCCAGACC 
CAGCAGTCGA AGTTTGTGAA CTGGCAGGTG GACGGGGAGT ATCGGGGCTC TGACTTCACA 
GCAGCCGTCA CCCTGGGGAA CCCAGACGTC CTCGTGGGTT CAGGAATCCT CGTAGCCCAC 
TACCTCCAGA GCATCACGCC TTGCCTGGCC CTGGGTGGAG AGCTGGTCTA CCACCGGCGG 
CCTGGAGAGG AGGGCACTGT CATGTCTCTA GCTGGGAAAT ACACATTGAA CAACTGGTTG 
GCAACGGTAA CGTTGGGCCA GGCGGGCATG CACGCAACAT ACTACCACAA AGCCAGTGAC 
CAGCTGCAGG TGGGTGTGGA GTTTGAGGCC AGCACAAGGA TGCAGGACAC CAGCGTCTCC 
TTCGGGTACC AGCTGGACCT GCCCAAGGCC AACCTCCTCT TCAAAGGTGC TGGAGGACAG 
TGTGCTGCCA CCCTGTGGGC CTCCACATTA CCAGGGAACA CTTGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TOMM40 ( XM_005258411.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005258468.1 Homo sapiens translocase of outer mitochondrial membrane 40 (TOMM40), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu51947
Clone ID Related Accession (Same CDS sequence)	XM_005258411.3 , XM_005258411.4
Accession Version	XM_005258411.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1008bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	mitochondrial import receptor subunit TOM40 homolog isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005258411.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGAACG TGTTGGCTGC CAGCTCGCCG CCCGCAGGGC CGCCACCGCC GCCTGCGCCG 
GCCCTCGTGG GGCTGCCGCC ACCTCCGCCC TCGCCGCCGG GCTTCACGCT GCCGCCGCTG 
GGAGGCAGCC TGGGCGCCGG CACCAGTACG AGTCGAAGTT CGGAACGGAC CCCCGGGGCT 
GCAACCGCCA GCGCCTCAGG GGCCGCCGAG GATGGGGCCT GCGGCTGCCT GCCCAACCCG 
GGCACATTCG AGGAGTGCCA CCGGAAGTGC AAGGAGCTGT TTCCCATTCA GATGGAGGGT 
GTCAAGCTCA CAGTCAACAA AGGGTTGAGT AACCATTTTC AGGTCAACCA CACAGTAGCC 
CTCAGCACAA TCGGGGAGTC CAACTACCAC TTCGGGGTCA CATATGTGGG GACAAAGCAG 
CTGAGTCCCA CAGAGGCGTT CCCTGTACTG GTGGGTGACA TGGACAACAG TGGCAGTCTC 
AACGCTCAGG TCATTCACCA GCTGGGCCCC GGTCTCAGGT CCAAGATGGC CATCCAGACC 
CAGCAGTCGA AGTTTGTGAA CTGGCAGGTG GACGGGGAGT ATCGGGGCTC TGACTTCACA 
GCAGCCGTCA CCCTGGGGAA CCCAGACGTC CTCGTGGGTT CAGGAATCCT CGTAGCCCAC 
TACCTCCAGA GCATCACGCC TTGCCTGGCC CTGGGTGGAG AGCTGGTCTA CCACCGGCGG 
CCTGGAGAGG AGGGCACTGT CATGTCTCTA GCTGGGAAAT ACACATTGAA CAACTGGTTG 
GCAACGGTAA CGTTGGGCCA GGCGGGCATG CACGCAACAT ACTACCACAA AGCCAGTGAC 
CAGCTGCAGG TGGGTGTGGA GTTTGAGGCC AGCACAAGGA TGCAGGACAC CAGCGTCTCC 
TTCGGGTACC AGCTGGACCT GCCCAAGGCC AACCTCCTCT TCAAAGGTGC TGGAGGACAG 
TGTGCTGCCA CCCTGTGGGC CTCCACATTA CCAGGGAACA CTTGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005258468.1
CDS	99..1106
Translation	MGNVLAASSPPAGPPPPPAPALVGLPPPPPSPPGFTLPPLGGSLGAGTSTSRSSERTPGAATASASGAAEDGACGCLPNPGTFEECHRKCKELFPIQMEGVKLTVNKGLSNHFQVNHTVALSTIGESNYHFGVTYVGTKQLSPTEAFPVLVGDMDNSGSLNAQVIHQLGPGLRSKMAIQTQQSKFVNWQVDGEYRGSDFTAAVTLGNPDVLVGSGILVAHYLQSITPCLALGGELVYHRRPGEEGTVMSLAGKYTLNNWLATVTLGQAGMHATYYHKASDQLQVGVEFEASTRMQDTSVSFGYQLDLPKANLLFKGAGGQCAATLWASTLPGNTC

Target ORF information:

RefSeq Version	XM_005258411.4
Organism	Homo sapiens(human)
Definition	Homo sapiens translocase of outer mitochondrial membrane 40 (TOMM40), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005258411.4

ORF Insert Sequence:

ATGGGGAACG TGTTGGCTGC CAGCTCGCCG CCCGCAGGGC CGCCACCGCC GCCTGCGCCG 
GCCCTCGTGG GGCTGCCGCC ACCTCCGCCC TCGCCGCCGG GCTTCACGCT GCCGCCGCTG 
GGAGGCAGCC TGGGCGCCGG CACCAGTACG AGTCGAAGTT CGGAACGGAC CCCCGGGGCT 
GCAACCGCCA GCGCCTCAGG GGCCGCCGAG GATGGGGCCT GCGGCTGCCT GCCCAACCCG 
GGCACATTCG AGGAGTGCCA CCGGAAGTGC AAGGAGCTGT TTCCCATTCA GATGGAGGGT 
GTCAAGCTCA CAGTCAACAA AGGGTTGAGT AACCATTTTC AGGTCAACCA CACAGTAGCC 
CTCAGCACAA TCGGGGAGTC CAACTACCAC TTCGGGGTCA CATATGTGGG GACAAAGCAG 
CTGAGTCCCA CAGAGGCGTT CCCTGTACTG GTGGGTGACA TGGACAACAG TGGCAGTCTC 
AACGCTCAGG TCATTCACCA GCTGGGCCCC GGTCTCAGGT CCAAGATGGC CATCCAGACC 
CAGCAGTCGA AGTTTGTGAA CTGGCAGGTG GACGGGGAGT ATCGGGGCTC TGACTTCACA 
GCAGCCGTCA CCCTGGGGAA CCCAGACGTC CTCGTGGGTT CAGGAATCCT CGTAGCCCAC 
TACCTCCAGA GCATCACGCC TTGCCTGGCC CTGGGTGGAG AGCTGGTCTA CCACCGGCGG 
CCTGGAGAGG AGGGCACTGT CATGTCTCTA GCTGGGAAAT ACACATTGAA CAACTGGTTG 
GCAACGGTAA CGTTGGGCCA GGCGGGCATG CACGCAACAT ACTACCACAA AGCCAGTGAC 
CAGCTGCAGG TGGGTGTGGA GTTTGAGGCC AGCACAAGGA TGCAGGACAC CAGCGTCTCC 
TTCGGGTACC AGCTGGACCT GCCCAAGGCC AACCTCCTCT TCAAAGGTGC TGGAGGACAG 
TGTGCTGCCA CCCTGTGGGC CTCCACATTA CCAGGGAACA CTTGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Neuropathologic features of TOMM40 '523 variant on late-life cognitive decline.
Alzheimer's & dementia : the journal of the Alzheimer's Association13(12)1380-1388(2017 Dec)
Yu L,Lutz MW,Farfel JM,Wilson RS,Burns DK,Saunders AM,De Jager PL,Barnes LL,Schneider JA,Bennett DA

The biological foundation of the genetic association of TOMM40 with late-onset Alzheimer's disease.
Biochimica et biophysica acta1863(11)2973-2986(2017 Nov)
Zeitlow K,Charlambous L,Ng I,Gagrani S,Mihovilovic M,Luo S,Rock DL,Saunders A,Roses AD,Gottschalk WK

Family history and TOMM40 '523 interactive associations with memory in middle-aged and Alzheimer's disease cohorts.
Alzheimer's & dementia : the journal of the Alzheimer's Association13(11)1217-1225(2017 Nov)
Willette AA,Webb JL,Lutz MW,Bendlin BB,Wennberg AM,Oh JM,Roses A,Koscik RL,Hermann BP,Dowling NM,Asthana S,Johnson SC,

APOE ?4-TOMM40 '523 haplotypes and the risk of Alzheimer's disease in older Caucasian and African Americans.
PloS one12(7)e0180356(2017)
Yu L,Lutz MW,Wilson RS,Burns DK,Roses AD,Saunders AM,Yang J,Gaiteri C,De Jager PL,Barnes LL,Bennett DA

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TOMM40 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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