RBM14 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RBM14
Entrez Gene ID	10432
Full Name	RNA binding motif protein 14
Synonyms	COAA,PSP2,SIP,SYTIP1,TMEM137
General protein information	Preferred Names RNA binding motif protein 14 Names RNA-binding protein 14 RRM-containing coactivator activator/modulator SYT-interacting protein paraspeckle protein 2 synaptotagmin-interacting protein transmembrane protein 137
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11q13.2
Summary	This gene encodes a ribonucleoprotein that functions as a general nuclear coactivator, and an RNA splicing modulator. This protein contains two RNA recognition motifs (RRM) at the N-terminus, and multiple hexapeptide repeat domain at the C-terminus that interacts with thyroid hormone receptor-binding protein (TRBP), and is required for transcription activation. Alternatively spliced transcript variants encoding different isoforms (with opposing effects on transcription) have been described for this gene. [provided by RefSeq, Oct 2011].
Disorder MIM:	612409

mRNA and Protein(s)

mRNA	Protein	Name
NM_001198836.2	NP_001185765.1	RNA-binding protein 14 isoform 2
NM_001198836.1	NP_001185765.1	RNA-binding protein 14 isoform 2
NM_001198837.1	NP_001185766.1	RNA-binding protein 14 isoform 3
NM_006328.3	NP_006319.1	RNA-binding protein 14 isoform 1
NM_001198837.2	NP_001185766.1	RNA-binding protein 14 isoform 3
NM_006328.4	NP_006319.1	RNA-binding protein 14 isoform 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	RBM14	NP_006319.1
Mus musculus (house mouse)	Rbm14	NP_063922.2
Rattus norvegicus (Norway rat)	Rbm14	NP_596879.1
Rattus norvegicus (Norway rat)	LOC100911677	XP_003749082.1
Gallus gallus (chicken)	RBM14	XP_423757.4
Xenopus tropicalis (tropical clawed frog)	rbm14	NP_989050.1
Pan troglodytes (chimpanzee)	RBM14	NP_001233311.1
Canis lupus familiaris (dog)	RBM14	XP_852283.2
Bos taurus (cattle)	RBM14	NP_001014901.1

Gene Ontology
Bibliography

Related articles in PubMed

HEXIM1 and NEAT1 Long Non-coding RNA Form a Multi-subunit Complex that Regulates DNA-Mediated Innate Immune Response.
Morchikh M, Cribier A, Raffel R, Amraoui S, Cau J, Severac D, Dubois E, Schwartz O, Bennasser Y, Benkirane M
Molecular cell67(3)387-399.e5(2017 Aug)

RNA-binding protein RBM14 regulates dissociation and association of non-homologous end joining proteins.
Simon NE, Yuan M, Kai M
Cell cycle (Georgetown, Tex.)16(12)1175-1180(2017 Jun)

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Yang X, Coulombe-Huntington J, Kang S, Sheynkman GM, Hao T, Richardson A, Sun S, Yang F, Shen YA, Murray RR, Spirohn K, Begg BE, Duran-Frigola M, MacWilliams A, Pevzner SJ, Zhong Q, Trigg SA, Tam S, Ghamsari L, Sahni N, Yi S, Rodriguez MD, Balcha D, Tan G, Costanzo M, Andrews B, Boone C, Zhou XJ, Salehi-Ashtiani K, Charloteaux B, Chen AA, Calderwood MA, Aloy P, Roth FP, Hill DE, Iakoucheva LM, Xia Y, Vidal M
Cell164(4)805-17(2016 Feb)

Prion-like domains in RNA binding proteins are essential for building subnuclear paraspeckles.
Hennig S, Kong G, Mannen T, Sadowska A, Kobelke S, Blythe A, Knott GJ, Iyer KS, Ho D, Newcombe EA, Hosoki K, Goshima N, Kawaguchi T, Hatters D, Trinkle-Mulcahy L, Hirose T, Bond CS, Fox AH
The Journal of cell biology210(4)529-39(2015 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

RBM14 connects key paraspeckle subcomplexes via interactions mediated by its prion-like domain.
Title: Prion-like domains in RNA binding proteins are essential for building subnuclear paraspeckles.

This study identifies a cellular protein named RBM14 that is associated with XPO1 (CRM1), a nuclear protein that binds to the HIV-1 Rev protein and mediates nuclear export of incompletely spliced HIV-1 viral RNAs
Title: Mining the human complexome database identifies RBM14 as an XPO1-associated protein involved in HIV-1 Rev function.

upon RBM14 depletion, a part of the ectopic centriolar protein complexes in turn assemble into structures more akin to centrioles, presumably by incorporating HsSAS-6, a cartwheel component, and cause multipolar spindle formation.
Title: RBM14 prevents assembly of centriolar protein complexes and maintains mitotic spindle integrity.

RBM14 promotes radio-resistance in glioblastoma by regulating DNA repair and cell differentiation.
Title: RNA binding protein RBM14 promotes radio-resistance in glioblastoma by regulating DNA repair and cell differentiation.

CoAA is involved in the migration-enhancing action of PEA3 on MCF7 metastatic human cancer cells.
Title: The coactivator activator CoAA regulates PEA3 group member transcriptional activity.

The following RBM14 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RBM14 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18436	NM_006328.4 Latest version!	Homo sapiens RNA binding motif protein 14 (RBM14), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu00132	NM_001198837.2 Latest version!	Homo sapiens RNA binding motif protein 14 (RBM14), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu01730	NM_001198836.2 Latest version!	Homo sapiens RNA binding motif protein 14 (RBM14), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu01730	NM_001198836.1	Homo sapiens RNA binding motif protein 14 (RBM14), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu00132	NM_001198837.1	Homo sapiens RNA binding motif protein 14 (RBM14), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu18436	NM_006328.3	Homo sapiens RNA binding motif protein 14 (RBM14), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RBM14 ( NM_006328.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_006319.1 Homo sapiens RNA binding motif protein 14 (RBM14), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu18436
Clone ID Related Accession (Same CDS sequence)	NM_006328.3 , NM_006328.4
Accession Version	NM_006328.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2010bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-20
Organism	Homo sapiens(human)
Product	RNA-binding protein 14 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB044990.1, AK021768.1 and AP001157.4. This sequence is a reference standard in the RefSeqGene project. On Aug 19, 2008 this sequence version replaced NM_006328.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1, also known as CoAA or coactivator activator). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.82629.1, SRR1660805.56451.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGATAT TCGTGGGCAA CGTCGACGGG GCGGATACGA CTCCGGAGGA GCTGGCAGCC 
CTCTTTGCGC CCTACGGCAC GGTCATGAGC TGCGCCGTCA TGAAACAGTT CGCCTTCGTG 
CACATGCGCG AGAACGCGGG CGCGCTGCGC GCCATCGAAG CCCTGCACGG CCACGAGCTG 
CGGCCGGGGC GCGCGCTCGT GGTGGAGATG TCGCGCCCAA GGCCTCTTAA TACTTGGAAG 
ATTTTCGTGG GCAATGTGTC GGCTGCATGC ACGAGCCAGG AACTGCGCAG CCTCTTCGAG 
CGCCGCGGAC GCGTCATCGA GTGTGACGTG GTGAAAGACT ACGCGTTTGT TCACATGGAG 
AAGGAAGCAG ATGCCAAAGC CGCAATCGCG CAGCTCAACG GCAAAGAAGT GAAGGGCAAG 
CGCATCAACG TGGAACTCTC CACCAAGGGT CAGAAGAAGG GGCCTGGCCT GGCTGTCCAG 
TCTGGGGACA AGACCAAGAA ACCAGGGGCT GGGGATACGG CCTTCCCTGG AACTGGTGGC 
TTCTCTGCCA CCTTCGACTA CCAGCAGGCT TTTGGCAACA GCACTGGTGG CTTTGATGGG 
CAAGCCCGTC AGCCCACACC ACCCTTCTTT GGTCGCGACC GCAGCCCTCT GCGCCGTTCA 
CCTCCCCGAG CCTCTTATGT GGCTCCTCTG ACGGCCCAGC CAGCTACCTA CCGGGCCCAG 
CCGTCCGTGT CACTGGGAGC TGCCTACAGG GCCCAGCCTT CTGCCTCTTT GGGTGTTGGC 
TATCGGACTC AGCCCATGAC AGCCCAGGCA GCCTCTTACC GCGCTCAGCC CTCTGTCTCC 
CTTGGGGCAC CATACAGGGG CCAGCTGGCT AGTCCTAGCT CCCAGTCTGC TGCAGCTTCT 
TCACTCGGCC CATATGGTGG AGCCCAGCCC TCAGCCTCGG CCCTTTCCTC CTATGGGGGT 
CAGGCAGCTG CAGCTTCTTC GCTCAACTCC TATGGGGCTC AGGGTTCCTC CCTTGCCTCC 
TATGGTAACC AGCCATCCTC TTACGGCGCC CAGGCTGCCT CTTCCTATGG GGTTCGTGCA 
GCTGCTTCTT CCTACAACAC CCAGGGAGCA GCTTCCTCCT TAGGCTCCTA CGGGGCTCAG 
GCAGCCTCCT ATGGGGCCCA GTCTGCAGCC TCCTCACTAG CTTATGGAGC CCAGGCAGCT 
TCATATAATG CCCAGCCCTC GGCCTCTTAC AATGCCCAGT CTGCCCCATA TGCTGCACAG 
CAGGCTGCTT CCTACTCTTC CCAACCTGCT GCCTATGTGG CACAGCCAGC CACAGCTGCT 
GCCTATGCCA GCCAGCCAGC AGCCTACGCC GCACAAGCCA CTACCCCAAT GGCTGGCTCC 
TATGGGGCCC AGCCGGTTGT GCAGACCCAG CTGAATAGTT ACGGGGCCCA AGCATCAATG 
GGCCTTTCAG GCTCCTATGG GGCTCAGTCG GCTGCTGCGG CCACTGGCTC CTATGGTGCC 
GCAGCAGCCT ACGGGGCCCA ACCTTCTGCC ACCCTGGCAG CTCCTTACCG CACTCAGTCA 
TCAGCCTCAT TGGCTGCTTC CTATGCTGCC CAGCAGCATC CCCAGGCTGC TGCCTCCTAC 
CGCGGCCAGC CAGGCAATGC CTACGATGGG GCAGGTCAGC CGTCTGCAGC CTACCTGTCC 
ATGTCCCAGG GGGCCGTTGC CAACGCCAAC AGCACCCCGC CGCCCTATGA GCGTACCCGC 
CTCTCCCCAC CCCGGGCCAG CTACGACGAT CCCTACAAAA AGGCTGTCGC CATGTCGAAA 
AGGTATGGTT CCGACCGGCG TTTAGCCGAG CTCTCTGATT ACCGCCGTTT ATCAGAGTCG 
CAGCTTTCGT TCCGCCGCTC GCCGACAAAG TCCTCGCTGG ATTACCGTCG CCTGCCCGAT 
GCCCATTCCG ATTACGCACG CTATTCGGGC TCCTATAATG ATTACCTGCG GGCGGCTCAG 
ATGCACTCTG GCTACCAGCG CCGCATGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006319.1
CDS	140..2149
Translation	MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFVHMRENAGALRAIEALHGHELRPGRALVVEMSRPRPLNTWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKDYAFVHMEKEADAKAAIAQLNGKEVKGKRINVELSTKGQKKGPGLAVQSGDKTKKPGAGDTAFPGTGGFSATFDYQQAFGNSTGGFDGQARQPTPPFFGRDRSPLRRSPPRASYVAPLTAQPATYRAQPSVSLGAAYRAQPSASLGVGYRTQPMTAQAASYRAQPSVSLGAPYRGQLASPSSQSAAASSLGPYGGAQPSASALSSYGGQAAAASSLNSYGAQGSSLASYGNQPSSYGAQAASSYGVRAAASSYNTQGAASSLGSYGAQAASYGAQSAASSLAYGAQAASYNAQPSASYNAQSAPYAAQQAASYSSQPAAYVAQPATAAAYASQPAAYAAQATTPMAGSYGAQPVVQTQLNSYGAQASMGLSGSYGAQSAAAATGSYGAAAAYGAQPSATLAAPYRTQSSASLAASYAAQQHPQAAASYRGQPGNAYDGAGQPSAAYLSMSQGAVANANSTPPPYERTRLSPPRASYDDPYKKAVAMSKRYGSDRRLAELSDYRRLSESQLSFRRSPTKSSLDYRRLPDAHSDYARYSGSYNDYLRAAQMHSGYQRRM

Target ORF information:

RefSeq Version	NM_006328.3
Organism	Homo sapiens(human)
Definition	Homo sapiens RNA binding motif protein 14 (RBM14), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006328.3

ORF Insert Sequence:

ATGAAGATAT TCGTGGGCAA CGTCGACGGG GCGGATACGA CTCCGGAGGA GCTGGCAGCC 
CTCTTTGCGC CCTACGGCAC GGTCATGAGC TGCGCCGTCA TGAAACAGTT CGCCTTCGTG 
CACATGCGCG AGAACGCGGG CGCGCTGCGC GCCATCGAAG CCCTGCACGG CCACGAGCTG 
CGGCCGGGGC GCGCGCTCGT GGTGGAGATG TCGCGCCCAA GGCCTCTTAA TACTTGGAAG 
ATTTTCGTGG GCAATGTGTC GGCTGCATGC ACGAGCCAGG AACTGCGCAG CCTCTTCGAG 
CGCCGCGGAC GCGTCATCGA GTGTGACGTG GTGAAAGACT ACGCGTTTGT TCACATGGAG 
AAGGAAGCAG ATGCCAAAGC CGCAATCGCG CAGCTCAACG GCAAAGAAGT GAAGGGCAAG 
CGCATCAACG TGGAACTCTC CACCAAGGGT CAGAAGAAGG GGCCTGGCCT GGCTGTCCAG 
TCTGGGGACA AGACCAAGAA ACCAGGGGCT GGGGATACGG CCTTCCCTGG AACTGGTGGC 
TTCTCTGCCA CCTTCGACTA CCAGCAGGCT TTTGGCAACA GCACTGGTGG CTTTGATGGG 
CAAGCCCGTC AGCCCACACC ACCCTTCTTT GGTCGCGACC GCAGCCCTCT GCGCCGTTCA 
CCTCCCCGAG CCTCTTATGT GGCTCCTCTG ACGGCCCAGC CAGCTACCTA CCGGGCCCAG 
CCGTCCGTGT CACTGGGAGC TGCCTACAGG GCCCAGCCTT CTGCCTCTTT GGGTGTTGGC 
TATCGGACTC AGCCCATGAC AGCCCAGGCA GCCTCTTACC GCGCTCAGCC CTCTGTCTCC 
CTTGGGGCAC CATACAGGGG CCAGCTGGCT AGTCCTAGCT CCCAGTCTGC TGCAGCTTCT 
TCACTCGGCC CATATGGTGG AGCCCAGCCC TCAGCCTCGG CCCTTTCCTC CTATGGGGGT 
CAGGCAGCTG CAGCTTCTTC GCTCAACTCC TATGGGGCTC AGGGTTCCTC CCTTGCCTCC 
TATGGTAACC AGCCATCCTC TTACGGCGCC CAGGCTGCCT CTTCCTATGG GGTTCGTGCA 
GCTGCTTCTT CCTACAACAC CCAGGGAGCA GCTTCCTCCT TAGGCTCCTA CGGGGCTCAG 
GCAGCCTCCT ATGGGGCCCA GTCTGCAGCC TCCTCACTAG CTTATGGAGC CCAGGCAGCT 
TCATATAATG CCCAGCCCTC GGCCTCTTAC AATGCCCAGT CTGCCCCATA TGCTGCACAG 
CAGGCTGCTT CCTACTCTTC CCAACCTGCT GCCTATGTGG CACAGCCAGC CACAGCTGCT 
GCCTATGCCA GCCAGCCAGC AGCCTACGCC GCACAAGCCA CTACCCCAAT GGCTGGCTCC 
TATGGGGCCC AGCCGGTTGT GCAGACCCAG CTGAATAGTT ACGGGGCCCA AGCATCAATG 
GGCCTTTCAG GCTCCTATGG GGCTCAGTCG GCTGCTGCGG CCACTGGCTC CTATGGTGCC 
GCAGCAGCCT ACGGGGCCCA ACCTTCTGCC ACCCTGGCAG CTCCTTACCG CACTCAGTCA 
TCAGCCTCAT TGGCTGCTTC CTATGCTGCC CAGCAGCATC CCCAGGCTGC TGCCTCCTAC 
CGCGGCCAGC CAGGCAATGC CTACGATGGG GCAGGTCAGC CGTCTGCAGC CTACCTGTCC 
ATGTCCCAGG GGGCCGTTGC CAACGCCAAC AGCACCCCGC CGCCCTATGA GCGTACCCGC 
CTCTCCCCAC CCCGGGCCAG CTACGACGAT CCCTACAAAA AGGCTGTCGC CATGTCGAAA 
AGGTATGGTT CCGACCGGCG TTTAGCCGAG CTCTCTGATT ACCGCCGTTT ATCAGAGTCG 
CAGCTTTCGT TCCGCCGCTC GCCGACAAAG TCCTCGCTGG ATTACCGTCG CCTGCCCGAT 
GCCCATTCCG ATTACGCACG CTATTCGGGC TCCTATAATG ATTACCTGCG GGCGGCTCAG 
ATGCACTCTG GCTACCAGCG CCGCATGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RBM14 ( NM_006328.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_006319.1 Homo sapiens RNA binding motif protein 14 (RBM14), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu18436
Clone ID Related Accession (Same CDS sequence)	NM_006328.3 , NM_006328.4
Accession Version	NM_006328.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2010bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-21
Organism	Homo sapiens(human)
Product	RNA-binding protein 14 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB044990.1, AK021768.1 and AP001157.4. This sequence is a reference standard in the RefSeqGene project. On Jun 2, 2019 this sequence version replaced NM_006328.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1, also known as CoAA or coactivator activator). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.67211.1, SRR1803612.77287.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAAGATAT TCGTGGGCAA CGTCGACGGG GCGGATACGA CTCCGGAGGA GCTGGCAGCC 
CTCTTTGCGC CCTACGGCAC GGTCATGAGC TGCGCCGTCA TGAAACAGTT CGCCTTCGTG 
CACATGCGCG AGAACGCGGG CGCGCTGCGC GCCATCGAAG CCCTGCACGG CCACGAGCTG 
CGGCCGGGGC GCGCGCTCGT GGTGGAGATG TCGCGCCCAA GGCCTCTTAA TACTTGGAAG 
ATTTTCGTGG GCAATGTGTC GGCTGCATGC ACGAGCCAGG AACTGCGCAG CCTCTTCGAG 
CGCCGCGGAC GCGTCATCGA GTGTGACGTG GTGAAAGACT ACGCGTTTGT TCACATGGAG 
AAGGAAGCAG ATGCCAAAGC CGCAATCGCG CAGCTCAACG GCAAAGAAGT GAAGGGCAAG 
CGCATCAACG TGGAACTCTC CACCAAGGGT CAGAAGAAGG GGCCTGGCCT GGCTGTCCAG 
TCTGGGGACA AGACCAAGAA ACCAGGGGCT GGGGATACGG CCTTCCCTGG AACTGGTGGC 
TTCTCTGCCA CCTTCGACTA CCAGCAGGCT TTTGGCAACA GCACTGGTGG CTTTGATGGG 
CAAGCCCGTC AGCCCACACC ACCCTTCTTT GGTCGCGACC GCAGCCCTCT GCGCCGTTCA 
CCTCCCCGAG CCTCTTATGT GGCTCCTCTG ACGGCCCAGC CAGCTACCTA CCGGGCCCAG 
CCGTCCGTGT CACTGGGAGC TGCCTACAGG GCCCAGCCTT CTGCCTCTTT GGGTGTTGGC 
TATCGGACTC AGCCCATGAC AGCCCAGGCA GCCTCTTACC GCGCTCAGCC CTCTGTCTCC 
CTTGGGGCAC CATACAGGGG CCAGCTGGCT AGTCCTAGCT CCCAGTCTGC TGCAGCTTCT 
TCACTCGGCC CATATGGTGG AGCCCAGCCC TCAGCCTCGG CCCTTTCCTC CTATGGGGGT 
CAGGCAGCTG CAGCTTCTTC GCTCAACTCC TATGGGGCTC AGGGTTCCTC CCTTGCCTCC 
TATGGTAACC AGCCATCCTC TTACGGCGCC CAGGCTGCCT CTTCCTATGG GGTTCGTGCA 
GCTGCTTCTT CCTACAACAC CCAGGGAGCA GCTTCCTCCT TAGGCTCCTA CGGGGCTCAG 
GCAGCCTCCT ATGGGGCCCA GTCTGCAGCC TCCTCACTAG CTTATGGAGC CCAGGCAGCT 
TCATATAATG CCCAGCCCTC GGCCTCTTAC AATGCCCAGT CTGCCCCATA TGCTGCACAG 
CAGGCTGCTT CCTACTCTTC CCAACCTGCT GCCTATGTGG CACAGCCAGC CACAGCTGCT 
GCCTATGCCA GCCAGCCAGC AGCCTACGCC GCACAAGCCA CTACCCCAAT GGCTGGCTCC 
TATGGGGCCC AGCCGGTTGT GCAGACCCAG CTGAATAGTT ACGGGGCCCA AGCATCAATG 
GGCCTTTCAG GCTCCTATGG GGCTCAGTCG GCTGCTGCGG CCACTGGCTC CTATGGTGCC 
GCAGCAGCCT ACGGGGCCCA ACCTTCTGCC ACCCTGGCAG CTCCTTACCG CACTCAGTCA 
TCAGCCTCAT TGGCTGCTTC CTATGCTGCC CAGCAGCATC CCCAGGCTGC TGCCTCCTAC 
CGCGGCCAGC CAGGCAATGC CTACGATGGG GCAGGTCAGC CGTCTGCAGC CTACCTGTCC 
ATGTCCCAGG GGGCCGTTGC CAACGCCAAC AGCACCCCGC CGCCCTATGA GCGTACCCGC 
CTCTCCCCAC CCCGGGCCAG CTACGACGAT CCCTACAAAA AGGCTGTCGC CATGTCGAAA 
AGGTATGGTT CCGACCGGCG TTTAGCCGAG CTCTCTGATT ACCGCCGTTT ATCAGAGTCG 
CAGCTTTCGT TCCGCCGCTC GCCGACAAAG TCCTCGCTGG ATTACCGTCG CCTGCCCGAT 
GCCCATTCCG ATTACGCACG CTATTCGGGC TCCTATAATG ATTACCTGCG GGCGGCTCAG 
ATGCACTCTG GCTACCAGCG CCGCATGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006319.1
CDS	92..2101
Translation	MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFVHMRENAGALRAIEALHGHELRPGRALVVEMSRPRPLNTWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKDYAFVHMEKEADAKAAIAQLNGKEVKGKRINVELSTKGQKKGPGLAVQSGDKTKKPGAGDTAFPGTGGFSATFDYQQAFGNSTGGFDGQARQPTPPFFGRDRSPLRRSPPRASYVAPLTAQPATYRAQPSVSLGAAYRAQPSASLGVGYRTQPMTAQAASYRAQPSVSLGAPYRGQLASPSSQSAAASSLGPYGGAQPSASALSSYGGQAAAASSLNSYGAQGSSLASYGNQPSSYGAQAASSYGVRAAASSYNTQGAASSLGSYGAQAASYGAQSAASSLAYGAQAASYNAQPSASYNAQSAPYAAQQAASYSSQPAAYVAQPATAAAYASQPAAYAAQATTPMAGSYGAQPVVQTQLNSYGAQASMGLSGSYGAQSAAAATGSYGAAAAYGAQPSATLAAPYRTQSSASLAASYAAQQHPQAAASYRGQPGNAYDGAGQPSAAYLSMSQGAVANANSTPPPYERTRLSPPRASYDDPYKKAVAMSKRYGSDRRLAELSDYRRLSESQLSFRRSPTKSSLDYRRLPDAHSDYARYSGSYNDYLRAAQMHSGYQRRM

Target ORF information:

RefSeq Version	NM_006328.4
Organism	Homo sapiens(human)
Definition	Homo sapiens RNA binding motif protein 14 (RBM14), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006328.4

ORF Insert Sequence:

ATGAAGATAT TCGTGGGCAA CGTCGACGGG GCGGATACGA CTCCGGAGGA GCTGGCAGCC 
CTCTTTGCGC CCTACGGCAC GGTCATGAGC TGCGCCGTCA TGAAACAGTT CGCCTTCGTG 
CACATGCGCG AGAACGCGGG CGCGCTGCGC GCCATCGAAG CCCTGCACGG CCACGAGCTG 
CGGCCGGGGC GCGCGCTCGT GGTGGAGATG TCGCGCCCAA GGCCTCTTAA TACTTGGAAG 
ATTTTCGTGG GCAATGTGTC GGCTGCATGC ACGAGCCAGG AACTGCGCAG CCTCTTCGAG 
CGCCGCGGAC GCGTCATCGA GTGTGACGTG GTGAAAGACT ACGCGTTTGT TCACATGGAG 
AAGGAAGCAG ATGCCAAAGC CGCAATCGCG CAGCTCAACG GCAAAGAAGT GAAGGGCAAG 
CGCATCAACG TGGAACTCTC CACCAAGGGT CAGAAGAAGG GGCCTGGCCT GGCTGTCCAG 
TCTGGGGACA AGACCAAGAA ACCAGGGGCT GGGGATACGG CCTTCCCTGG AACTGGTGGC 
TTCTCTGCCA CCTTCGACTA CCAGCAGGCT TTTGGCAACA GCACTGGTGG CTTTGATGGG 
CAAGCCCGTC AGCCCACACC ACCCTTCTTT GGTCGCGACC GCAGCCCTCT GCGCCGTTCA 
CCTCCCCGAG CCTCTTATGT GGCTCCTCTG ACGGCCCAGC CAGCTACCTA CCGGGCCCAG 
CCGTCCGTGT CACTGGGAGC TGCCTACAGG GCCCAGCCTT CTGCCTCTTT GGGTGTTGGC 
TATCGGACTC AGCCCATGAC AGCCCAGGCA GCCTCTTACC GCGCTCAGCC CTCTGTCTCC 
CTTGGGGCAC CATACAGGGG CCAGCTGGCT AGTCCTAGCT CCCAGTCTGC TGCAGCTTCT 
TCACTCGGCC CATATGGTGG AGCCCAGCCC TCAGCCTCGG CCCTTTCCTC CTATGGGGGT 
CAGGCAGCTG CAGCTTCTTC GCTCAACTCC TATGGGGCTC AGGGTTCCTC CCTTGCCTCC 
TATGGTAACC AGCCATCCTC TTACGGCGCC CAGGCTGCCT CTTCCTATGG GGTTCGTGCA 
GCTGCTTCTT CCTACAACAC CCAGGGAGCA GCTTCCTCCT TAGGCTCCTA CGGGGCTCAG 
GCAGCCTCCT ATGGGGCCCA GTCTGCAGCC TCCTCACTAG CTTATGGAGC CCAGGCAGCT 
TCATATAATG CCCAGCCCTC GGCCTCTTAC AATGCCCAGT CTGCCCCATA TGCTGCACAG 
CAGGCTGCTT CCTACTCTTC CCAACCTGCT GCCTATGTGG CACAGCCAGC CACAGCTGCT 
GCCTATGCCA GCCAGCCAGC AGCCTACGCC GCACAAGCCA CTACCCCAAT GGCTGGCTCC 
TATGGGGCCC AGCCGGTTGT GCAGACCCAG CTGAATAGTT ACGGGGCCCA AGCATCAATG 
GGCCTTTCAG GCTCCTATGG GGCTCAGTCG GCTGCTGCGG CCACTGGCTC CTATGGTGCC 
GCAGCAGCCT ACGGGGCCCA ACCTTCTGCC ACCCTGGCAG CTCCTTACCG CACTCAGTCA 
TCAGCCTCAT TGGCTGCTTC CTATGCTGCC CAGCAGCATC CCCAGGCTGC TGCCTCCTAC 
CGCGGCCAGC CAGGCAATGC CTACGATGGG GCAGGTCAGC CGTCTGCAGC CTACCTGTCC 
ATGTCCCAGG GGGCCGTTGC CAACGCCAAC AGCACCCCGC CGCCCTATGA GCGTACCCGC 
CTCTCCCCAC CCCGGGCCAG CTACGACGAT CCCTACAAAA AGGCTGTCGC CATGTCGAAA 
AGGTATGGTT CCGACCGGCG TTTAGCCGAG CTCTCTGATT ACCGCCGTTT ATCAGAGTCG 
CAGCTTTCGT TCCGCCGCTC GCCGACAAAG TCCTCGCTGG ATTACCGTCG CCTGCCCGAT 
GCCCATTCCG ATTACGCACG CTATTCGGGC TCCTATAATG ATTACCTGCG GGCGGCTCAG 
ATGCACTCTG GCTACCAGCG CCGCATGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RBM14 ( NM_001198837.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001185766.1 Homo sapiens RNA binding motif protein 14 (RBM14), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu00132
Clone ID Related Accession (Same CDS sequence)	NM_001198837.1 , NM_001198837.2
Accession Version	NM_001198837.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 360bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-02
Organism	Homo sapiens(human)
Product	RNA-binding protein 14 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB044990.1, DQ294957.1 and AP001157.4. Transcript Variant: This variant (3) lacks an internal coding exon compared to variant 1. This results in a frame-shift and an isoform (3, also known as CoAR or coactivator regulator) with a distinct and shorter C-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: KU178522.1, DQ294957.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145245, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGATAT TCGTGGGCAA CGTCGACGGG GCGGATACGA CTCCGGAGGA GCTGGCAGCC 
CTCTTTGCGC CCTACGGCAC GGTCATGAGC TGCGCCGTCA TGAAACAGTT CGCCTTCGTG 
CACATGCGCG AGAACGCGGG CGCGCTGCGC GCCATCGAAG CCCTGCACGG CCACGAGCTG 
CGGCCGGGGC GCGCGCTCGT GGTGGAGATG TCGCGCCCAA GGCCTCTTAA TACTTGGAAG 
ATTTTCGTGG GCAATGTGTC GGCTGCATGC ACGAGCCAGG AACTGCGCAG CCTCTTCGAG 
CGCCGCGGAC GCGTCATCGA GTGTGACGTG GTGAAAGGTA TGGTTCCGAC CGGCGTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001185766.1
CDS	140..499
Translation	MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFVHMRENAGALRAIEALHGHELRPGRALVVEMSRPRPLNTWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKGMVPTGV

Target ORF information:

RefSeq Version	NM_001198837.1
Organism	Homo sapiens(human)
Definition	Homo sapiens RNA binding motif protein 14 (RBM14), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001198837.1

ORF Insert Sequence:

ATGAAGATAT TCGTGGGCAA CGTCGACGGG GCGGATACGA CTCCGGAGGA GCTGGCAGCC 
CTCTTTGCGC CCTACGGCAC GGTCATGAGC TGCGCCGTCA TGAAACAGTT CGCCTTCGTG 
CACATGCGCG AGAACGCGGG CGCGCTGCGC GCCATCGAAG CCCTGCACGG CCACGAGCTG 
CGGCCGGGGC GCGCGCTCGT GGTGGAGATG TCGCGCCCAA GGCCTCTTAA TACTTGGAAG 
ATTTTCGTGG GCAATGTGTC GGCTGCATGC ACGAGCCAGG AACTGCGCAG CCTCTTCGAG 
CGCCGCGGAC GCGTCATCGA GTGTGACGTG GTGAAAGGTA TGGTTCCGAC CGGCGTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RBM14 ( NM_001198837.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001185766.1 Homo sapiens RNA binding motif protein 14 (RBM14), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu00132
Clone ID Related Accession (Same CDS sequence)	NM_001198837.1 , NM_001198837.2
Accession Version	NM_001198837.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 360bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-01
Organism	Homo sapiens(human)
Product	RNA-binding protein 14 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB044990.1, DQ294957.1 and AP001157.4. On Jun 2, 2019 this sequence version replaced NM_001198837.1. Transcript Variant: This variant (3) lacks an internal coding exon compared to variant 1. This results in a frame-shift and an isoform (3, also known as CoAR or coactivator regulator) with a distinct and shorter C-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189655.124744.1, DRR138527.530272.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145245, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGATAT TCGTGGGCAA CGTCGACGGG GCGGATACGA CTCCGGAGGA GCTGGCAGCC 
CTCTTTGCGC CCTACGGCAC GGTCATGAGC TGCGCCGTCA TGAAACAGTT CGCCTTCGTG 
CACATGCGCG AGAACGCGGG CGCGCTGCGC GCCATCGAAG CCCTGCACGG CCACGAGCTG 
CGGCCGGGGC GCGCGCTCGT GGTGGAGATG TCGCGCCCAA GGCCTCTTAA TACTTGGAAG 
ATTTTCGTGG GCAATGTGTC GGCTGCATGC ACGAGCCAGG AACTGCGCAG CCTCTTCGAG 
CGCCGCGGAC GCGTCATCGA GTGTGACGTG GTGAAAGGTA TGGTTCCGAC CGGCGTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001185766.1
CDS	92..451
Translation	MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFVHMRENAGALRAIEALHGHELRPGRALVVEMSRPRPLNTWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKGMVPTGV

Target ORF information:

RefSeq Version	NM_001198837.2
Organism	Homo sapiens(human)
Definition	Homo sapiens RNA binding motif protein 14 (RBM14), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001198837.2

ORF Insert Sequence:

ATGAAGATAT TCGTGGGCAA CGTCGACGGG GCGGATACGA CTCCGGAGGA GCTGGCAGCC 
CTCTTTGCGC CCTACGGCAC GGTCATGAGC TGCGCCGTCA TGAAACAGTT CGCCTTCGTG 
CACATGCGCG AGAACGCGGG CGCGCTGCGC GCCATCGAAG CCCTGCACGG CCACGAGCTG 
CGGCCGGGGC GCGCGCTCGT GGTGGAGATG TCGCGCCCAA GGCCTCTTAA TACTTGGAAG 
ATTTTCGTGG GCAATGTGTC GGCTGCATGC ACGAGCCAGG AACTGCGCAG CCTCTTCGAG 
CGCCGCGGAC GCGTCATCGA GTGTGACGTG GTGAAAGGTA TGGTTCCGAC CGGCGTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RBM14 ( NM_001198836.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001185765.1 Homo sapiens RNA binding motif protein 14 (RBM14), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu01730
Clone ID Related Accession (Same CDS sequence)	NM_001198836.2 , NM_001198836.1
Accession Version	NM_001198836.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 471bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-01
Organism	Homo sapiens(human)
Product	RNA-binding protein 14 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF315633.1 and AP001157.4. On Jun 2, 2019 this sequence version replaced NM_001198836.1. Transcript Variant: This variant (2) uses an alternate donor splice site at an internal coding exon compared to variant 1. This results in a frame-shift and an isoform (2, also known as CoAM or coactivator modulator) with a distinct and shorter C-terminus compared to isoform 1. This isoform lacks the TRBP-interacting domain, and functions as a transcriptional repressor by inhibiting the activity of isoform 1 (PMID:11443112). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189652.240145.1, AF315633.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGATAT TCGTGGGCAA CGTCGACGGG GCGGATACGA CTCCGGAGGA GCTGGCAGCC 
CTCTTTGCGC CCTACGGCAC GGTCATGAGC TGCGCCGTCA TGAAACAGTT CGCCTTCGTG 
CACATGCGCG AGAACGCGGG CGCGCTGCGC GCCATCGAAG CCCTGCACGG CCACGAGCTG 
CGGCCGGGGC GCGCGCTCGT GGTGGAGATG TCGCGCCCAA GGCCTCTTAA TACTTGGAAG 
ATTTTCGTGG GCAATGTGTC GGCTGCATGC ACGAGCCAGG AACTGCGCAG CCTCTTCGAG 
CGCCGCGGAC GCGTCATCGA GTGTGACGTG GTGAAAGACT ACGCGTTTGT TCACATGGAG 
AAGGAAGCAG ATGCCAAAGC CGCAATCGCG CAGCTCAACG GCAAAGAAGT GAAGGGCAAG 
CGCATCAACG TGGAACTCTC CACCAAGGGT ATGGTTCCGA CCGGCGTTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001185765.1
CDS	92..562
Translation	MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFVHMRENAGALRAIEALHGHELRPGRALVVEMSRPRPLNTWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKDYAFVHMEKEADAKAAIAQLNGKEVKGKRINVELSTKGMVPTGV

Target ORF information:

RefSeq Version	NM_001198836.2
Organism	Homo sapiens(human)
Definition	Homo sapiens RNA binding motif protein 14 (RBM14), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001198836.2

ORF Insert Sequence:

ATGAAGATAT TCGTGGGCAA CGTCGACGGG GCGGATACGA CTCCGGAGGA GCTGGCAGCC 
CTCTTTGCGC CCTACGGCAC GGTCATGAGC TGCGCCGTCA TGAAACAGTT CGCCTTCGTG 
CACATGCGCG AGAACGCGGG CGCGCTGCGC GCCATCGAAG CCCTGCACGG CCACGAGCTG 
CGGCCGGGGC GCGCGCTCGT GGTGGAGATG TCGCGCCCAA GGCCTCTTAA TACTTGGAAG 
ATTTTCGTGG GCAATGTGTC GGCTGCATGC ACGAGCCAGG AACTGCGCAG CCTCTTCGAG 
CGCCGCGGAC GCGTCATCGA GTGTGACGTG GTGAAAGACT ACGCGTTTGT TCACATGGAG 
AAGGAAGCAG ATGCCAAAGC CGCAATCGCG CAGCTCAACG GCAAAGAAGT GAAGGGCAAG 
CGCATCAACG TGGAACTCTC CACCAAGGGT ATGGTTCCGA CCGGCGTTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RBM14 ( NM_001198836.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001185765.1 Homo sapiens RNA binding motif protein 14 (RBM14), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu01730
Clone ID Related Accession (Same CDS sequence)	NM_001198836.2 , NM_001198836.1
Accession Version	NM_001198836.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 471bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-02
Organism	Homo sapiens(human)
Product	RNA-binding protein 14 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB044990.1, AF315633.1 and AP001157.4. Transcript Variant: This variant (2) uses an alternate donor splice site at an internal coding exon compared to variant 1. This results in a frame-shift and an isoform (2, also known as CoAM or coactivator modulator) with a distinct and shorter C-terminus compared to isoform 1. This isoform lacks the TRBP-interacting domain, and functions as a transcriptional repressor by inhibiting the activity of isoform 1 (PMID:11443112). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF315633.1, KU178521.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGATAT TCGTGGGCAA CGTCGACGGG GCGGATACGA CTCCGGAGGA GCTGGCAGCC 
CTCTTTGCGC CCTACGGCAC GGTCATGAGC TGCGCCGTCA TGAAACAGTT CGCCTTCGTG 
CACATGCGCG AGAACGCGGG CGCGCTGCGC GCCATCGAAG CCCTGCACGG CCACGAGCTG 
CGGCCGGGGC GCGCGCTCGT GGTGGAGATG TCGCGCCCAA GGCCTCTTAA TACTTGGAAG 
ATTTTCGTGG GCAATGTGTC GGCTGCATGC ACGAGCCAGG AACTGCGCAG CCTCTTCGAG 
CGCCGCGGAC GCGTCATCGA GTGTGACGTG GTGAAAGACT ACGCGTTTGT TCACATGGAG 
AAGGAAGCAG ATGCCAAAGC CGCAATCGCG CAGCTCAACG GCAAAGAAGT GAAGGGCAAG 
CGCATCAACG TGGAACTCTC CACCAAGGGT ATGGTTCCGA CCGGCGTTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001185765.1
CDS	140..610
Translation	MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFVHMRENAGALRAIEALHGHELRPGRALVVEMSRPRPLNTWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKDYAFVHMEKEADAKAAIAQLNGKEVKGKRINVELSTKGMVPTGV

Target ORF information:

RefSeq Version	NM_001198836.1
Organism	Homo sapiens(human)
Definition	Homo sapiens RNA binding motif protein 14 (RBM14), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001198836.1

ORF Insert Sequence:

ATGAAGATAT TCGTGGGCAA CGTCGACGGG GCGGATACGA CTCCGGAGGA GCTGGCAGCC 
CTCTTTGCGC CCTACGGCAC GGTCATGAGC TGCGCCGTCA TGAAACAGTT CGCCTTCGTG 
CACATGCGCG AGAACGCGGG CGCGCTGCGC GCCATCGAAG CCCTGCACGG CCACGAGCTG 
CGGCCGGGGC GCGCGCTCGT GGTGGAGATG TCGCGCCCAA GGCCTCTTAA TACTTGGAAG 
ATTTTCGTGG GCAATGTGTC GGCTGCATGC ACGAGCCAGG AACTGCGCAG CCTCTTCGAG 
CGCCGCGGAC GCGTCATCGA GTGTGACGTG GTGAAAGACT ACGCGTTTGT TCACATGGAG 
AAGGAAGCAG ATGCCAAAGC CGCAATCGCG CAGCTCAACG GCAAAGAAGT GAAGGGCAAG 
CGCATCAACG TGGAACTCTC CACCAAGGGT ATGGTTCCGA CCGGCGTTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

HEXIM1 and NEAT1 Long Non-coding RNA Form a Multi-subunit Complex that Regulates DNA-Mediated Innate Immune Response.
Molecular cell67(3)387-399.e5(2017 Aug)
Morchikh M,Cribier A,Raffel R,Amraoui S,Cau J,Severac D,Dubois E,Schwartz O,Bennasser Y,Benkirane M

RNA-binding protein RBM14 regulates dissociation and association of non-homologous end joining proteins.
Cell cycle (Georgetown, Tex.)16(12)1175-1180(2017 Jun)
Simon NE,Yuan M,Kai M

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Cell164(4)805-17(2016 Feb)
Yang X,Coulombe-Huntington J,Kang S,Sheynkman GM,Hao T,Richardson A,Sun S,Yang F,Shen YA,Murray RR,Spirohn K,Begg BE,Duran-Frigola M,MacWilliams A,Pevzner SJ,Zhong Q,Trigg SA,Tam S,Ghamsari L,Sahni N,Yi S,Rodriguez MD,Balcha D,Tan G,Costanzo M,Andrews B,Boone C,Zhou XJ,Salehi-Ashtiani K,Charloteaux B,Chen AA,Calderwood MA,Aloy P,Roth FP,Hill DE,Iakoucheva LM,Xia Y,Vidal M

Prion-like domains in RNA binding proteins are essential for building subnuclear paraspeckles.
The Journal of cell biology210(4)529-39(2015 Aug)
Hennig S,Kong G,Mannen T,Sadowska A,Kobelke S,Blythe A,Knott GJ,Iyer KS,Ho D,Newcombe EA,Hosoki K,Goshima N,Kawaguchi T,Hatters D,Trinkle-Mulcahy L,Hirose T,Bond CS,Fox AH

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RBM14 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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