Gene Symbol | YAP1 |
Entrez Gene ID | 10413 |
Full Name | Yes associated protein 1 |
Synonyms | COB1,YAP,YAP2,YAP65,YKI |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013]. |
Disorder MIM: | |
Disorder Html: | Coloboma, ocular, with or without hearing impairment, cleft lip/palate, and/or mental retardation, 120433 (3); Coloboma, ocular, 120433 (3) |