CCL26 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CCL26
Entrez Gene ID	10344
Full Name	C-C motif chemokine ligand 26
Synonyms	IMAC,MIP-4a,MIP-4alpha,SCYA26,TSC-1
General protein information	Preferred Names C-C motif chemokine ligand 26 Names C-C motif chemokine 26 CC chemokine IMAC MIP-4-alpha chemokine (C-C motif) ligand 26 chemokine N1 eotaxin-3 macrophage inflammatory protein 4-alpha small inducible cytokine A26 small inducible cytokine subfamily A (Cys-Cys), member 26 thymic stroma chemokine-1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7q11.23
Summary	This gene is one of two Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 7. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for normal peripheral blood eosinophils and basophils. The product of this gene is one of three related chemokines that specifically activate chemokine receptor CCR3. This chemokine may contribute to the eosinophil accumulation in atopic diseases. [provided by RefSeq, Jul 2008].
Disorder MIM:	604697

mRNA and Protein(s)

mRNA	Protein	Name
XM_017011672.1	XP_016867161.1	C-C motif chemokine 26 isoform X2
NM_001371938.1	NP_001358867.1	C-C motif chemokine 26 precursor
XM_017011671.1	XP_016867160.1	C-C motif chemokine 26 isoform X1
NM_001371936.1	NP_001358865.1	C-C motif chemokine 26 precursor
NM_006072.4	NP_006063.1	C-C motif chemokine 26 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CCL26	XP_527791.1
Canis lupus familiaris (dog)	CCL26	NP_001005253.1
Bos taurus (cattle)	CCL26	NP_001192564.1
	CCL26	XP_001109808.1
Homo sapiens (human)	CCL26	NP_006063.1

Gene Ontology
Bibliography

Related articles in PubMed

CCL26 Participates in the PRL-3-Induced Promotion of Colorectal Cancer Invasion by Stimulating Tumor-Associated Macrophage Infiltration.
Lan Q, Lai W, Zeng Y, Liu L, Li S, Jin S, Zhang Y, Luo X, Xu H, Lin X, Chu Z
Molecular cancer therapeutics17(1)276-289(2018 Jan)

Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation.
von Hundelshausen P, Agten SM, Eckardt V, Blanchet X, Schmitt MM, Ippel H, Neideck C, Bidzhekov K, Leberzammer J, Wichapong K, Faussner A, Drechsler M, Grommes J, van Geffen JP, Li H, Ortega-Gomez A, Megens RT, Naumann R, Dijkgraaf I, Nicolaes GA, D?ring Y, Soehnlein O, Lutgens E, Heemskerk JW, Koenen RR, Mayo KH, Hackeng TM, Weber C
Science translational medicine9(384)(2017 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Based on the ADEPT study data set, we report that airway mucosal expression of CCL26 was a robust discriminator of type 2 inflammation from healthy nonatopic subjects. Furthermore, airway mucosal CCL26 expression was best identified by using a panel of clinical biomarkers, including Feno values, bEOS counts, and expression of 2 novel markers, sCCL17 and sCCL26
Title: Identification of airway mucosal type 2 inflammation by using clinical biomarkers in asthmatic patients.

The reduction of circulating levels of MCP-4, eotaxin-3, and MIP-1beta could be one of the mechanisms by which bariatric surgery contributes to the reduction of cardiovascular risk in these patients.
Title: Circulating Levels of the Adipokines Monocyte Chemotactic Protein-4 (MCP-4), Macrophage Inflammatory Protein-1? (MIP-1?), and Eotaxin-3 in Severe Obesity and Following Bariatric Surgery.

this study shows that expression of CCL26 is increased in eosinophilic myocarditis patients compared to chronic lymphocytic myocarditis patients
Title: Macrophages and cardiac fibroblasts are the main producers of eotaxins and regulate eosinophil trafficking to the heart.

hypoxia-inducible factors activate the transcription of chemokine ligand 26 in cancer cells to recruit chemokine receptor 1-expressing myeloid-derived suppressor cells to the primary tumor
Title: Hypoxia induces myeloid-derived suppressor cell recruitment to hepatocellular carcinoma through chemokine (C-C motif) ligand 26.

Review: eotaxins (CCL11, CCL24, and CCL26) play key role(s) during symptomatic inflammatory responses raised in response to allergic crisis of allergic asthma and atopic dermatitis
Title: An Overlook to the Characteristics and Roles Played by Eotaxin Network in the Pathophysiology of Food Allergies: Allergic Asthma and Atopic Dermatitis.

The following CCL26 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CCL26 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18575	NM_006072.4 Latest version!	Homo sapiens C-C motif chemokine ligand 26 (CCL26), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu18575	NM_001371938.1 Latest version!	Homo sapiens C-C motif chemokine ligand 26 (CCL26), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu18575	NM_001371936.1 Latest version!	Homo sapiens C-C motif chemokine ligand 26 (CCL26), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu18575	XM_017011672.1 Latest version!	Homo sapiens C-C motif chemokine ligand 26 (CCL26), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu97003	XM_017011671.1 Latest version!	Homo sapiens C-C motif chemokine ligand 26 (CCL26), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CCL26 ( NM_001371938.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001358867.1 Homo sapiens C-C motif chemokine ligand 26 (CCL26), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu18575
Clone ID Related Accession (Same CDS sequence)	XM_017011672.1 , NM_001371938.1 , NM_001371936.1 , NM_006072.4
Accession Version	NM_001371938.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 285bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-29
Organism	Homo sapiens(human)
Product	C-C motif chemokine 26 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC005102.1. On Jul 29, 2019 this sequence version replaced XM_017011671.1. Transcript Variant: This variant (2) has a shorter 5' UTR compared to variant 1 since it represents use of the main transcription initiation site, as defined by CAGE data. All three variants encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BF590082.1, BG211121.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGATGGGCC TCTCCTTGGC CTCTGCTGTG CTCCTGGCCT CCCTCCTGAG TCTCCACCTT 
GGAACTGCCA CACGTGGGAG TGACATATCC AAGACCTGCT GCTTCCAATA CAGCCACAAG 
CCCCTTCCCT GGACCTGGGT GCGAAGCTAT GAATTCACCA GTAACAGCTG CTCCCAGCGG 
GCTGTGATAT TCACTACCAA AAGAGGCAAG AAAGTCTGTA CCCATCCAAG GAAAAAATGG 
GTGCAAAAAT ACATTTCTTT ACTGAAAACT CCGAAACAAT TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001358867.1
CDS	36..320
Translation	MMGLSLASAVLLASLLSLHLGTATRGSDISKTCCFQYSHKPLPWTWVRSYEFTSNSCSQRAVIFTTKRGKKVCTHPRKKWVQKYISLLKTPKQL

Target ORF information:

RefSeq Version	NM_001371938.1
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine ligand 26 (CCL26), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001371938.1

ORF Insert Sequence:

ATGATGGGCC TCTCCTTGGC CTCTGCTGTG CTCCTGGCCT CCCTCCTGAG TCTCCACCTT 
GGAACTGCCA CACGTGGGAG TGACATATCC AAGACCTGCT GCTTCCAATA CAGCCACAAG 
CCCCTTCCCT GGACCTGGGT GCGAAGCTAT GAATTCACCA GTAACAGCTG CTCCCAGCGG 
GCTGTGATAT TCACTACCAA AAGAGGCAAG AAAGTCTGTA CCCATCCAAG GAAAAAATGG 
GTGCAAAAAT ACATTTCTTT ACTGAAAACT CCGAAACAAT TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCL26 ( NM_001371936.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001358865.1 Homo sapiens C-C motif chemokine ligand 26 (CCL26), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu18575
Clone ID Related Accession (Same CDS sequence)	XM_017011672.1 , NM_001371938.1 , NM_001371936.1 , NM_006072.4
Accession Version	NM_001371936.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 285bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Homo sapiens(human)
Product	C-C motif chemokine 26 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC005102.1. On Jul 29, 2019 this sequence version replaced XM_017011672.1. Transcript Variant: This variant (1) represents the longest transcript. All three variants encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DRR138524.428220.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATGGGCC TCTCCTTGGC CTCTGCTGTG CTCCTGGCCT CCCTCCTGAG TCTCCACCTT 
GGAACTGCCA CACGTGGGAG TGACATATCC AAGACCTGCT GCTTCCAATA CAGCCACAAG 
CCCCTTCCCT GGACCTGGGT GCGAAGCTAT GAATTCACCA GTAACAGCTG CTCCCAGCGG 
GCTGTGATAT TCACTACCAA AAGAGGCAAG AAAGTCTGTA CCCATCCAAG GAAAAAATGG 
GTGCAAAAAT ACATTTCTTT ACTGAAAACT CCGAAACAAT TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001358865.1
CDS	209..493
Translation	MMGLSLASAVLLASLLSLHLGTATRGSDISKTCCFQYSHKPLPWTWVRSYEFTSNSCSQRAVIFTTKRGKKVCTHPRKKWVQKYISLLKTPKQL

Target ORF information:

RefSeq Version	NM_001371936.1
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine ligand 26 (CCL26), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001371936.1

ORF Insert Sequence:

ATGATGGGCC TCTCCTTGGC CTCTGCTGTG CTCCTGGCCT CCCTCCTGAG TCTCCACCTT 
GGAACTGCCA CACGTGGGAG TGACATATCC AAGACCTGCT GCTTCCAATA CAGCCACAAG 
CCCCTTCCCT GGACCTGGGT GCGAAGCTAT GAATTCACCA GTAACAGCTG CTCCCAGCGG 
GCTGTGATAT TCACTACCAA AAGAGGCAAG AAAGTCTGTA CCCATCCAAG GAAAAAATGG 
GTGCAAAAAT ACATTTCTTT ACTGAAAACT CCGAAACAAT TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCL26 ( NM_006072.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_006063.1 Homo sapiens C-C motif chemokine ligand 26 (CCL26), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu18575
Clone ID Related Accession (Same CDS sequence)	XM_017011672.1 , NM_001371938.1 , NM_001371936.1 , NM_006072.4
Accession Version	NM_006072.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 285bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-06
Organism	Homo sapiens(human)
Product	C-C motif chemokine 26 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY358893.1 and AF096296.1. This sequence is a reference standard in the RefSeqGene project. On Sep 8, 2004 this sequence version replaced NM_006072.3. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. All three variants encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BX103172.1, AY358893.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2145245 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATGGGCC TCTCCTTGGC CTCTGCTGTG CTCCTGGCCT CCCTCCTGAG TCTCCACCTT 
GGAACTGCCA CACGTGGGAG TGACATATCC AAGACCTGCT GCTTCCAATA CAGCCACAAG 
CCCCTTCCCT GGACCTGGGT GCGAAGCTAT GAATTCACCA GTAACAGCTG CTCCCAGCGG 
GCTGTGATAT TCACTACCAA AAGAGGCAAG AAAGTCTGTA CCCATCCAAG GAAAAAATGG 
GTGCAAAAAT ACATTTCTTT ACTGAAAACT CCGAAACAAT TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006063.1
CDS	109..393
Translation	MMGLSLASAVLLASLLSLHLGTATRGSDISKTCCFQYSHKPLPWTWVRSYEFTSNSCSQRAVIFTTKRGKKVCTHPRKKWVQKYISLLKTPKQL

Target ORF information:

RefSeq Version	NM_006072.4
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine ligand 26 (CCL26), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006072.4

ORF Insert Sequence:

ATGATGGGCC TCTCCTTGGC CTCTGCTGTG CTCCTGGCCT CCCTCCTGAG TCTCCACCTT 
GGAACTGCCA CACGTGGGAG TGACATATCC AAGACCTGCT GCTTCCAATA CAGCCACAAG 
CCCCTTCCCT GGACCTGGGT GCGAAGCTAT GAATTCACCA GTAACAGCTG CTCCCAGCGG 
GCTGTGATAT TCACTACCAA AAGAGGCAAG AAAGTCTGTA CCCATCCAAG GAAAAAATGG 
GTGCAAAAAT ACATTTCTTT ACTGAAAACT CCGAAACAAT TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCL26 ( XM_017011672.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016867161.1 Homo sapiens C-C motif chemokine ligand 26 (CCL26), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu18575
Clone ID Related Accession (Same CDS sequence)	XM_017011672.1 , NM_001371938.1 , NM_001371936.1 , NM_006072.4
Accession Version	XM_017011672.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 285bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-12
Organism	Homo sapiens(human)
Product	C-C motif chemokine 26 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20190607 Annotation Version :: 109.20190607 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Freeze :: 20190607 ##Genome-Annotation-Data-END##

ATGATGGGCC TCTCCTTGGC CTCTGCTGTG CTCCTGGCCT CCCTCCTGAG TCTCCACCTT 
GGAACTGCCA CACGTGGGAG TGACATATCC AAGACCTGCT GCTTCCAATA CAGCCACAAG 
CCCCTTCCCT GGACCTGGGT GCGAAGCTAT GAATTCACCA GTAACAGCTG CTCCCAGCGG 
GCTGTGATAT TCACTACCAA AAGAGGCAAG AAAGTCTGTA CCCATCCAAG GAAAAAATGG 
GTGCAAAAAT ACATTTCTTT ACTGAAAACT CCGAAACAAT TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016867161.1
CDS	195..479
Translation	MMGLSLASAVLLASLLSLHLGTATRGSDISKTCCFQYSHKPLPWTWVRSYEFTSNSCSQRAVIFTTKRGKKVCTHPRKKWVQKYISLLKTPKQL

Target ORF information:

RefSeq Version	XM_017011672.1
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine ligand 26 (CCL26), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017011672.1

ORF Insert Sequence:

ATGATGGGCC TCTCCTTGGC CTCTGCTGTG CTCCTGGCCT CCCTCCTGAG TCTCCACCTT 
GGAACTGCCA CACGTGGGAG TGACATATCC AAGACCTGCT GCTTCCAATA CAGCCACAAG 
CCCCTTCCCT GGACCTGGGT GCGAAGCTAT GAATTCACCA GTAACAGCTG CTCCCAGCGG 
GCTGTGATAT TCACTACCAA AAGAGGCAAG AAAGTCTGTA CCCATCCAAG GAAAAAATGG 
GTGCAAAAAT ACATTTCTTT ACTGAAAACT CCGAAACAAT TGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCL26 ( XM_017011671.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016867160.1 Homo sapiens C-C motif chemokine ligand 26 (CCL26), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu97003
Clone ID Related Accession (Same CDS sequence)	XM_017011671.1
Accession Version	XM_017011671.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 447bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-12
Organism	Homo sapiens(human)
Product	C-C motif chemokine 26 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20190607 Annotation Version :: 109.20190607 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Freeze :: 20190607 ##Genome-Annotation-Data-END##

ATGAGTATTA GTTTACTTTT CCTTTGTTGG GTCAAAAGTG CTGCTTCTGT TCCCAACCAC 
AGAATTCTCT GGAATTGTTT TCAGGGCCGT CTCAGTCTCA TAAAAGGGGA TCAGGCAGGA 
GGAGTTTGGG AGAAACCTGA GAAGGGCCTG ATTTGCAGCA TCATGATGGG CCTCTCCTTG 
GCCTCTGCTG TGCTCCTGGC CTCCCTCCTG AGTCTCCACC TTGGAACTGC CACACGTGGG 
AGTGACATAT CCAAGACCTG CTGCTTCCAA TACAGCCACA AGCCCCTTCC CTGGACCTGG 
GTGCGAAGCT ATGAATTCAC CAGTAACAGC TGCTCCCAGC GGGCTGTGAT ATTCACTACC 
AAAAGAGGCA AGAAAGTCTG TACCCATCCA AGGAAAAAAT GGGTGCAAAA ATACATTTCT 
TTACTGAAAA CTCCGAAACA ATTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016867160.1
CDS	25..471
Translation	MSISLLFLCWVKSAASVPNHRILWNCFQGRLSLIKGDQAGGVWEKPEKGLICSIMMGLSLASAVLLASLLSLHLGTATRGSDISKTCCFQYSHKPLPWTWVRSYEFTSNSCSQRAVIFTTKRGKKVCTHPRKKWVQKYISLLKTPKQL

Target ORF information:

RefSeq Version	XM_017011671.1
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine ligand 26 (CCL26), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017011671.1

ORF Insert Sequence:

ATGAGTATTA GTTTACTTTT CCTTTGTTGG GTCAAAAGTG CTGCTTCTGT TCCCAACCAC 
AGAATTCTCT GGAATTGTTT TCAGGGCCGT CTCAGTCTCA TAAAAGGGGA TCAGGCAGGA 
GGAGTTTGGG AGAAACCTGA GAAGGGCCTG ATTTGCAGCA TCATGATGGG CCTCTCCTTG 
GCCTCTGCTG TGCTCCTGGC CTCCCTCCTG AGTCTCCACC TTGGAACTGC CACACGTGGG 
AGTGACATAT CCAAGACCTG CTGCTTCCAA TACAGCCACA AGCCCCTTCC CTGGACCTGG 
GTGCGAAGCT ATGAATTCAC CAGTAACAGC TGCTCCCAGC GGGCTGTGAT ATTCACTACC 
AAAAGAGGCA AGAAAGTCTG TACCCATCCA AGGAAAAAAT GGGTGCAAAA ATACATTTCT 
TTACTGAAAA CTCCGAAACA ATTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

CCL26 Participates in the PRL-3-Induced Promotion of Colorectal Cancer Invasion by Stimulating Tumor-Associated Macrophage Infiltration.
Molecular cancer therapeutics17(1)276-289(2018 Jan)
Lan Q,Lai W,Zeng Y,Liu L,Li S,Jin S,Zhang Y,Luo X,Xu H,Lin X,Chu Z

Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation.
Science translational medicine9(384)(2017 Apr)
von Hundelshausen P,Agten SM,Eckardt V,Blanchet X,Schmitt MM,Ippel H,Neideck C,Bidzhekov K,Leberzammer J,Wichapong K,Faussner A,Drechsler M,Grommes J,van Geffen JP,Li H,Ortega-Gomez A,Megens RT,Naumann R,Dijkgraaf I,Nicolaes GA,D?ring Y,Soehnlein O,Lutgens E,Heemskerk JW,Koenen RR,Mayo KH,Hackeng TM,Weber C

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CCL26 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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