Gene Symbol | KATNB1 |
Entrez Gene ID | 10300 |
Full Name | katanin regulatory subunit B1 |
Synonyms | KAT,LIS6 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. Katanin is a member of the AAA family of ATPases. [provided by RefSeq, Jul 2008]. |
Disorder MIM: | |
Disorder Html: | Lissencephaly 6, with microcephaly, 616212 (3) |