Gene Symbol | TRAIP |
Entrez Gene ID | 10293 |
Full Name | TRAF interacting protein |
Synonyms | RNF206,SCKL9,TRIP |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a protein that contains an N-terminal RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis. [provided by RefSeq, Jul 2008]. |
Disorder MIM: | |
Disorder Html: | Seckel syndrome 9, 616777 (3) |