CDKN2A gene cDNA ORF clone, Homo sapiens(human)

mRNA	Protein	Name
XM_005251343.1	XP_005251400.1	cyclin-dependent kinase inhibitor 2A isoform X3
NM_001195132.1	NP_001182061.1	cyclin-dependent kinase inhibitor 2A isoform p16gamma
NM_058195.3	NP_478102.2	cyclin-dependent kinase inhibitor 2A isoform p14ARF
XM_011517675.2	XP_011515977.1	cyclin-dependent kinase inhibitor 2A isoform X1
NM_000077.4	NP_000068.1	cyclin-dependent kinase inhibitor 2A isoform p16INK4a
NM_001363763.2	NP_001350692.1	cyclin-dependent kinase inhibitor 2A isoform 6
XM_011517676.2	XP_011515978.1	cyclin-dependent kinase inhibitor 2A isoform X2
NM_058197.4	NP_478104.2	cyclin-dependent kinase inhibitor 2A isoform p12
NM_001363763.1	NP_001350692.1	cyclin-dependent kinase inhibitor 2A isoform 6
XM_011517679.1	XP_011515981.1	cyclin-dependent kinase inhibitor 2A isoform X3

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18438	NM_058195.3 Latest version!	Homo sapiens cyclin dependent kinase inhibitor 2A (CDKN2A), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu21665	NM_058197.4 Latest version!	Homo sapiens cyclin dependent kinase inhibitor 2A (CDKN2A), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu22894	NM_000077.4 Latest version!	Homo sapiens cyclin dependent kinase inhibitor 2A (CDKN2A), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu23110	NM_001195132.1 Latest version!	Homo sapiens cyclin dependent kinase inhibitor 2A (CDKN2A), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu56798	XM_011517675.2 Latest version!	Homo sapiens cyclin dependent kinase inhibitor 2A (CDKN2A), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu56799	XM_011517676.2 Latest version!	Homo sapiens cyclin dependent kinase inhibitor 2A (CDKN2A), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu42655	NM_001363763.2 Latest version!	Homo sapiens cyclin dependent kinase inhibitor 2A (CDKN2A), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
OHu42655	XM_011517679.1 Latest version!	Homo sapiens cyclin-dependent kinase inhibitor 2A (CDKN2A), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
OHu42655	XM_005251343.1 Latest version!	Homo sapiens cyclin dependent kinase inhibitor 2A (CDKN2A), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
View Old Accession Versions >>
OHu42655	NM_001363763.1	Homo sapiens cyclin dependent kinase inhibitor 2A (CDKN2A), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
Hide Old Accession Versions >>

CDKN2A ( NM_058195.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_478102.2 Homo sapiens cyclin dependent kinase inhibitor 2A (CDKN2A), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu18438
Clone ID Related Accession (Same CDS sequence)	NM_058195.3
Accession Version	NM_058195.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 399bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Homo sapiens(human)
Product	cyclin-dependent kinase inhibitor 2A isoform p14ARF
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from U38945.1, S78535.1, BQ012762.1 and BX099567.1. This sequence is a reference standard in the RefSeqGene project. On or before Aug 31, 2013 this sequence version replaced XR_242496.1, NM_058195.2. Transcript Variant: This variant (4), also known as beta, encodes p14ARF. Transcripts 1 and 4, encoding p16INK4a and p14ARF have distinct first exons which contain the translation start codon, and share a common second exon, which is translated in different reading frames. Thus, the p14ARF protein encoded by this variant (4) lacks sequence similarity to the protein product of variant 1 (p16INK4a). Note that this variant may use an alternative upstream start codon, which would produce an isoform that is 41 aa longer at the N-terminus, or an alternative downstream start codon, which would produce an isoform (smARF, described in PMID:16713577) that is 47 aa shorter at the N-terminus; it is unclear if the isoforms derived from the alternative start codons are present in vivo. The p14ARF protein is known to be nucleoplasmic but may also be recruited to mitochondria, as described in PMID:20107316. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: KC806059.1, U26727.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: community standard (PMID:9724636) NMD candidate :: PMID: 9724636, 12082609, 18004878, 18583933, 19115249 ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGTGCGCA GGTTCTTGGT GACCCTCCGG ATTCGGCGCG CGTGCGGCCC GCCGCGAGTG 
AGGGTTTTCG TGGTTCACAT CCCGCGGCTC ACGGGGGAGT GGGCAGCGCC AGGGGCGCCC 
GCCGCTGTGG CCCTCGTGCT GATGCTACTG AGGAGCCAGC GTCTAGGGCA GCAGCCGCTT 
CCTAGAAGAC CAGGTCATGA TGATGGGCAG CGCCCGAGTG GCGGAGCTGC TGCTGCTCCA 
CGGCGCGGAG CCCAACTGCG CCGACCCCGC CACTCTCACC CGACCCGTGC ACGACGCTGC 
CCGGGAGGGC TTCCTGGACA CGCTGGTGGT GCTGCACCGG GCCGGGGCGC GGCTGGACGT 
GCGCGATGCC TGGGGCCGTC TGCCCGTGGA CCTGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_478102.2
CDS	161..559
Translation	MVRRFLVTLRIRRACGPPRVRVFVVHIPRLTGEWAAPGAPAAVALVLMLLRSQRLGQQPLPRRPGHDDGQRPSGGAAAAPRRGAQLRRPRHSHPTRARRCPGGLPGHAGGAAPGRGAAGRARCLGPSARGPG

Target ORF information:

RefSeq Version	NM_058195.3
Organism	Homo sapiens(human)
Definition	Homo sapiens cyclin dependent kinase inhibitor 2A (CDKN2A), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_058195.3

ORF Insert Sequence:

ATGGTGCGCA GGTTCTTGGT GACCCTCCGG ATTCGGCGCG CGTGCGGCCC GCCGCGAGTG 
AGGGTTTTCG TGGTTCACAT CCCGCGGCTC ACGGGGGAGT GGGCAGCGCC AGGGGCGCCC 
GCCGCTGTGG CCCTCGTGCT GATGCTACTG AGGAGCCAGC GTCTAGGGCA GCAGCCGCTT 
CCTAGAAGAC CAGGTCATGA TGATGGGCAG CGCCCGAGTG GCGGAGCTGC TGCTGCTCCA 
CGGCGCGGAG CCCAACTGCG CCGACCCCGC CACTCTCACC CGACCCGTGC ACGACGCTGC 
CCGGGAGGGC TTCCTGGACA CGCTGGTGGT GCTGCACCGG GCCGGGGCGC GGCTGGACGT 
GCGCGATGCC TGGGGCCGTC TGCCCGTGGA CCTGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDKN2A ( NM_058197.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_478104.2 Homo sapiens cyclin dependent kinase inhibitor 2A (CDKN2A), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu21665
Clone ID Related Accession (Same CDS sequence)	NM_058197.4
Accession Version	NM_058197.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 351bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Homo sapiens(human)
Product	cyclin-dependent kinase inhibitor 2A isoform p12
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL449423.14, AF115544.1, BQ012762.1 and BX099567.1. On Jul 20, 2010 this sequence version replaced NM_058197.3. Transcript Variant: This variant (3) contains an alternate open reading frame (ARF), when compared to variants 1 or 4. The ARF results from an alternative splicing between a distinct first exon, which contains the translation start codon, and the common second exon. Thus, the protein encoded by this variant (p12) lacks sequence similarity to the protein product of variant 4. This variant is specifically expressed in pancreas, and has been described in PMID:10445844. It is a candidate for nonsense-mediated mRNA decay (NMD), but it is not known if the endogenous protein is expressed in vivo. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF115544.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## NMD candidate :: translation inferred ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAGCCGG CGGCGGGGAG CAGCATGGAG CCTTCGGCTG ACTGGCTGGC CACGGCCGCG 
GCCCGGGGTC GGGTAGAGGA GGTGCGGGCG CTGCTGGAGG CGGGGGCGCT GCCCAACGCA 
CCGAATAGTT ACGGTCGGAG GCCGATCCAG GTGGGTAGAG GGTCTGCAGC GGGAGCAGGG 
GATGGCGGGC GACTCTGGAG GACGAAGTTT GCAGGGGAAT TGGAATCAGG TAGCGCTTCG 
ATTCTCCGGA AAAAGGGGAG GCTTCCTGGG GAGTTTTCAG AAGGGGTTTG TAATCACAGA 
CCTCCTCCTG GCGACGCCCT GGGGGCTTGG GAAGCCAAGG AAGAGGAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_478104.2
CDS	1..351
Translation	MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVGRGSAAGAGDGGRLWRTKFAGELESGSASILRKKGRLPGEFSEGVCNHRPPPGDALGAWEAKEEE

Target ORF information:

RefSeq Version	NM_058197.4
Organism	Homo sapiens(human)
Definition	Homo sapiens cyclin dependent kinase inhibitor 2A (CDKN2A), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_058197.4

ORF Insert Sequence:

ATGGAGCCGG CGGCGGGGAG CAGCATGGAG CCTTCGGCTG ACTGGCTGGC CACGGCCGCG 
GCCCGGGGTC GGGTAGAGGA GGTGCGGGCG CTGCTGGAGG CGGGGGCGCT GCCCAACGCA 
CCGAATAGTT ACGGTCGGAG GCCGATCCAG GTGGGTAGAG GGTCTGCAGC GGGAGCAGGG 
GATGGCGGGC GACTCTGGAG GACGAAGTTT GCAGGGGAAT TGGAATCAGG TAGCGCTTCG 
ATTCTCCGGA AAAAGGGGAG GCTTCCTGGG GAGTTTTCAG AAGGGGTTTG TAATCACAGA 
CCTCCTCCTG GCGACGCCCT GGGGGCTTGG GAAGCCAAGG AAGAGGAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDKN2A ( NM_000077.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_000068.1 Homo sapiens cyclin dependent kinase inhibitor 2A (CDKN2A), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu22894
Clone ID Related Accession (Same CDS sequence)	NM_000077.4
Accession Version	NM_000077.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 471bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Homo sapiens(human)
Product	cyclin-dependent kinase inhibitor 2A isoform p16INK4a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL449423.14, BI258230.1, L27211.1, BQ012762.1 and BX099567.1. This sequence is a reference standard in the RefSeqGene project. On Jul 20, 2010 this sequence version replaced NM_000077.3. Transcript Variant: This variant (1) is also known as alpha. Transcripts 1 and 4, encoding p16INK4a and p14ARF, have distinct first exons which contain the translation start codon, and share a common second exon, which is translated in different reading frames. Thus, the p16INK4a protein encoded by this variant (1) lacks sequence similarity to the protein product of variant 4 (p14ARF). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: L27211.1, KC814157.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGCCGG CGGCGGGGAG CAGCATGGAG CCTTCGGCTG ACTGGCTGGC CACGGCCGCG 
GCCCGGGGTC GGGTAGAGGA GGTGCGGGCG CTGCTGGAGG CGGGGGCGCT GCCCAACGCA 
CCGAATAGTT ACGGTCGGAG GCCGATCCAG GTCATGATGA TGGGCAGCGC CCGAGTGGCG 
GAGCTGCTGC TGCTCCACGG CGCGGAGCCC AACTGCGCCG ACCCCGCCAC TCTCACCCGA 
CCCGTGCACG ACGCTGCCCG GGAGGGCTTC CTGGACACGC TGGTGGTGCT GCACCGGGCC 
GGGGCGCGGC TGGACGTGCG CGATGCCTGG GGCCGTCTGC CCGTGGACCT GGCTGAGGAG 
CTGGGCCATC GCGATGTCGC ACGGTACCTG CGCGCGGCTG CGGGGGGCAC CAGAGGCAGT 
AACCATGCCC GCATAGATGC CGCGGAAGGT CCCTCAGACA TCCCCGATTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000068.1
CDS	307..777
Translation	MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGGTRGSNHARIDAAEGPSDIPD

Target ORF information:

RefSeq Version	NM_000077.4
Organism	Homo sapiens(human)
Definition	Homo sapiens cyclin dependent kinase inhibitor 2A (CDKN2A), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000077.4

ORF Insert Sequence:

ATGGAGCCGG CGGCGGGGAG CAGCATGGAG CCTTCGGCTG ACTGGCTGGC CACGGCCGCG 
GCCCGGGGTC GGGTAGAGGA GGTGCGGGCG CTGCTGGAGG CGGGGGCGCT GCCCAACGCA 
CCGAATAGTT ACGGTCGGAG GCCGATCCAG GTCATGATGA TGGGCAGCGC CCGAGTGGCG 
GAGCTGCTGC TGCTCCACGG CGCGGAGCCC AACTGCGCCG ACCCCGCCAC TCTCACCCGA 
CCCGTGCACG ACGCTGCCCG GGAGGGCTTC CTGGACACGC TGGTGGTGCT GCACCGGGCC 
GGGGCGCGGC TGGACGTGCG CGATGCCTGG GGCCGTCTGC CCGTGGACCT GGCTGAGGAG 
CTGGGCCATC GCGATGTCGC ACGGTACCTG CGCGCGGCTG CGGGGGGCAC CAGAGGCAGT 
AACCATGCCC GCATAGATGC CGCGGAAGGT CCCTCAGACA TCCCCGATTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDKN2A ( NM_001195132.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001182061.1 Homo sapiens cyclin dependent kinase inhibitor 2A (CDKN2A), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu23110
Clone ID Related Accession (Same CDS sequence)	NM_001195132.1
Accession Version	NM_001195132.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 504bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Homo sapiens(human)
Product	cyclin-dependent kinase inhibitor 2A isoform p16gamma
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL449423.14, DQ318021.1 and BX099567.1. Transcript Variant: This variant (5) includes an additional exon that causes a frameshift in the 3' coding region, compared to variant 1 (encoding p16INK4a). The resulting isoform (p16gamma) has a distinct C-terminus and is longer than p16INK4a. This variant has been described in PMID:17486064. It is a candidate for nonsense-mediated mRNA decay (NMD), but it is not known if the endogenous protein is expressed in vivo. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DQ318021.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## NMD candidate :: translation inferred ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGCCGG CGGCGGGGAG CAGCATGGAG CCTTCGGCTG ACTGGCTGGC CACGGCCGCG 
GCCCGGGGTC GGGTAGAGGA GGTGCGGGCG CTGCTGGAGG CGGGGGCGCT GCCCAACGCA 
CCGAATAGTT ACGGTCGGAG GCCGATCCAG GTCATGATGA TGGGCAGCGC CCGAGTGGCG 
GAGCTGCTGC TGCTCCACGG CGCGGAGCCC AACTGCGCCG ACCCCGCCAC TCTCACCCGA 
CCCGTGCACG ACGCTGCCCG GGAGGGCTTC CTGGACACGC TGGTGGTGCT GCACCGGGCC 
GGGGCGCGGC TGGACGTGCG CGATGCCTGG GGCCGTCTGC CCGTGGACCT GGCTGAGGAG 
CTGGGCCATC GCGATGTCGC ACGGTACCTG CGCGCGGCTG CGGGGGGCAC CAGAGGCAGT 
AACCATGCCC GCATAGATGC CGCGGAAGGT CCCTCAGAAA TGATCGGAAA CCATTTGTGG 
GTTTGTAGAA GCAGGCATGC GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001182061.1
CDS	307..810
Translation	MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGGTRGSNHARIDAAEGPSEMIGNHLWVCRSRHA

Target ORF information:

RefSeq Version	NM_001195132.1
Organism	Homo sapiens(human)
Definition	Homo sapiens cyclin dependent kinase inhibitor 2A (CDKN2A), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001195132.1

ORF Insert Sequence:

ATGGAGCCGG CGGCGGGGAG CAGCATGGAG CCTTCGGCTG ACTGGCTGGC CACGGCCGCG 
GCCCGGGGTC GGGTAGAGGA GGTGCGGGCG CTGCTGGAGG CGGGGGCGCT GCCCAACGCA 
CCGAATAGTT ACGGTCGGAG GCCGATCCAG GTCATGATGA TGGGCAGCGC CCGAGTGGCG 
GAGCTGCTGC TGCTCCACGG CGCGGAGCCC AACTGCGCCG ACCCCGCCAC TCTCACCCGA 
CCCGTGCACG ACGCTGCCCG GGAGGGCTTC CTGGACACGC TGGTGGTGCT GCACCGGGCC 
GGGGCGCGGC TGGACGTGCG CGATGCCTGG GGCCGTCTGC CCGTGGACCT GGCTGAGGAG 
CTGGGCCATC GCGATGTCGC ACGGTACCTG CGCGCGGCTG CGGGGGGCAC CAGAGGCAGT 
AACCATGCCC GCATAGATGC CGCGGAAGGT CCCTCAGAAA TGATCGGAAA CCATTTGTGG 
GTTTGTAGAA GCAGGCATGC GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDKN2A ( XM_011517675.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011515977.1 Homo sapiens cyclin dependent kinase inhibitor 2A (CDKN2A), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu56798
Clone ID Related Accession (Same CDS sequence)	XM_011517675.2
Accession Version	XM_011517675.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 555bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	cyclin-dependent kinase inhibitor 2A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011517675.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCCGG CGGCGGGGAG CAGCATGGAG CCTTCGGCTG ACTGGCTGGC CACGGCCGCG 
GCCCGGGGTC GGGTAGAGGA GGTGCGGGCG CTGCTGGAGG CGGGGGCGCT GCCCAACGCA 
CCGAATAGTT ACGGTCGGAG GCCGATCCAG GTCATGATGA TGGGCAGCGC CCGAGTGGCG 
GAGCTGCTGC TGCTCCACGG CGCGGAGCCC AACTGCGCCG ACCCCGCCAC TCTCACCCGA 
CCCGTGCACG ACGCTGCCCG GGAGGGCTTC CTGGACACGC TGGTGGTGCT GCACCGGGCC 
GGGGCGCGGC TGGACGTGCG CGATGCCTGG GGCCGTCTGC CCGTGGACCT GGCTGAGGAG 
CTGGGCCATC GCGATGTCGC ACGGTACCTG CGCGCGGCTG CGGGGGGCAC CAGAGGCAGT 
AACCATGCCC GCATAGATGC CGCGGAAGGT CCCTCAGCTG GCTGGACCAA CCTCAGGATT 
TCCAAACCCA ATTGTGCGTG GCATCATCTG GAGATCTCTC GATCTCGGCT CTTCTGCACA 
ACTCAACTAA TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011515977.1
CDS	331..885
Translation	MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGGTRGSNHARIDAAEGPSAGWTNLRISKPNCAWHHLEISRSRLFCTTQLI

Target ORF information:

RefSeq Version	XM_011517675.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cyclin dependent kinase inhibitor 2A (CDKN2A), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011517675.2

ORF Insert Sequence:

ATGGAGCCGG CGGCGGGGAG CAGCATGGAG CCTTCGGCTG ACTGGCTGGC CACGGCCGCG 
GCCCGGGGTC GGGTAGAGGA GGTGCGGGCG CTGCTGGAGG CGGGGGCGCT GCCCAACGCA 
CCGAATAGTT ACGGTCGGAG GCCGATCCAG GTCATGATGA TGGGCAGCGC CCGAGTGGCG 
GAGCTGCTGC TGCTCCACGG CGCGGAGCCC AACTGCGCCG ACCCCGCCAC TCTCACCCGA 
CCCGTGCACG ACGCTGCCCG GGAGGGCTTC CTGGACACGC TGGTGGTGCT GCACCGGGCC 
GGGGCGCGGC TGGACGTGCG CGATGCCTGG GGCCGTCTGC CCGTGGACCT GGCTGAGGAG 
CTGGGCCATC GCGATGTCGC ACGGTACCTG CGCGCGGCTG CGGGGGGCAC CAGAGGCAGT 
AACCATGCCC GCATAGATGC CGCGGAAGGT CCCTCAGCTG GCTGGACCAA CCTCAGGATT 
TCCAAACCCA ATTGTGCGTG GCATCATCTG GAGATCTCTC GATCTCGGCT CTTCTGCACA 
ACTCAACTAA TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDKN2A ( XM_011517676.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011515978.1 Homo sapiens cyclin dependent kinase inhibitor 2A (CDKN2A), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu56799
Clone ID Related Accession (Same CDS sequence)	XM_011517676.2
Accession Version	XM_011517676.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 519bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	cyclin-dependent kinase inhibitor 2A isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011517676.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCCGG CGGCGGGGAG CAGCATGGAG CCTTCGGCTG ACTGGCTGGC CACGGCCGCG 
GCCCGGGGTC GGGTAGAGGA GGTGCGGGCG CTGCTGGAGG CGGGGGCGCT GCCCAACGCA 
CCGAATAGTT ACGGTCGGAG GCCGATCCAG GTCATGATGA TGGGCAGCGC CCGAGTGGCG 
GAGCTGCTGC TGCTCCACGG CGCGGAGCCC AACTGCGCCG ACCCCGCCAC TCTCACCCGA 
CCCGTGCACG ACGCTGCCCG GGAGGGCTTC CTGGACACGC TGGTGGTGCT GCACCGGGCC 
GGGGCGCGGC TGGACGTGCG CGATGCCTGG GGCCGTCTGC CCGTGGACCT GGCTGAGGAG 
CTGGGCCATC GCGATGTCGC ACGGTACCTG CGCGCGGCTG CGGGGGGCAC CAGAGGCAGT 
AACCATGCCC GCATAGATGC CGCGGAAGGT CCCTCAGTTA CAGCTAGCAT CCAGGTCCCG 
GGAGGTGAAG AAGGAGACTT CGGCTCCAGT TACAGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011515978.1
CDS	331..849
Translation	MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGGTRGSNHARIDAAEGPSVTASIQVPGGEEGDFGSSYS

Target ORF information:

RefSeq Version	XM_011517676.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cyclin dependent kinase inhibitor 2A (CDKN2A), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011517676.2

ORF Insert Sequence:

ATGGAGCCGG CGGCGGGGAG CAGCATGGAG CCTTCGGCTG ACTGGCTGGC CACGGCCGCG 
GCCCGGGGTC GGGTAGAGGA GGTGCGGGCG CTGCTGGAGG CGGGGGCGCT GCCCAACGCA 
CCGAATAGTT ACGGTCGGAG GCCGATCCAG GTCATGATGA TGGGCAGCGC CCGAGTGGCG 
GAGCTGCTGC TGCTCCACGG CGCGGAGCCC AACTGCGCCG ACCCCGCCAC TCTCACCCGA 
CCCGTGCACG ACGCTGCCCG GGAGGGCTTC CTGGACACGC TGGTGGTGCT GCACCGGGCC 
GGGGCGCGGC TGGACGTGCG CGATGCCTGG GGCCGTCTGC CCGTGGACCT GGCTGAGGAG 
CTGGGCCATC GCGATGTCGC ACGGTACCTG CGCGCGGCTG CGGGGGGCAC CAGAGGCAGT 
AACCATGCCC GCATAGATGC CGCGGAAGGT CCCTCAGTTA CAGCTAGCAT CCAGGTCCCG 
GGAGGTGAAG AAGGAGACTT CGGCTCCAGT TACAGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDKN2A ( NM_001363763.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001350692.1 Homo sapiens cyclin dependent kinase inhibitor 2A (CDKN2A), transcript variant 6, mRNA.

Price & Availability↑

CloneID	OHu42655
Clone ID Related Accession (Same CDS sequence)	XM_005251343.1 , NM_001363763.2 , NM_001363763.1 , XM_011517679.1
Accession Version	NM_001363763.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 318bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	cyclin-dependent kinase inhibitor 2A isoform 6
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL449423.14. On Jun 2, 2019 this sequence version replaced NM_001363763.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7346977.566937.1, BF347035.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2150385, SAMN01820689 [ECO:0000348] ##Evidence-Data-END##

ATGATGATGG GCAGCGCCCG AGTGGCGGAG CTGCTGCTGC TCCACGGCGC GGAGCCCAAC 
TGCGCCGACC CCGCCACTCT CACCCGACCC GTGCACGACG CTGCCCGGGA GGGCTTCCTG 
GACACGCTGG TGGTGCTGCA CCGGGCCGGG GCGCGGCTGG ACGTGCGCGA TGCCTGGGGC 
CGTCTGCCCG TGGACCTGGC TGAGGAGCTG GGCCATCGCG ATGTCGCACG GTACCTGCGC 
GCGGCTGCGG GGGGCACCAG AGGCAGTAAC CATGCCCGCA TAGATGCCGC GGAAGGTCCC 
TCAGACATCC CCGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001350692.1
CDS	508..825
Translation	MMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGGTRGSNHARIDAAEGPSDIPD

Target ORF information:

RefSeq Version	NM_001363763.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cyclin dependent kinase inhibitor 2A (CDKN2A), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001363763.2

ORF Insert Sequence:

ATGATGATGG GCAGCGCCCG AGTGGCGGAG CTGCTGCTGC TCCACGGCGC GGAGCCCAAC 
TGCGCCGACC CCGCCACTCT CACCCGACCC GTGCACGACG CTGCCCGGGA GGGCTTCCTG 
GACACGCTGG TGGTGCTGCA CCGGGCCGGG GCGCGGCTGG ACGTGCGCGA TGCCTGGGGC 
CGTCTGCCCG TGGACCTGGC TGAGGAGCTG GGCCATCGCG ATGTCGCACG GTACCTGCGC 
GCGGCTGCGG GGGGCACCAG AGGCAGTAAC CATGCCCGCA TAGATGCCGC GGAAGGTCCC 
TCAGACATCC CCGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDKN2A ( NM_001363763.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001350692.1 Homo sapiens cyclin dependent kinase inhibitor 2A (CDKN2A), transcript variant 6, mRNA.

Price & Availability↑

CloneID	OHu42655
Clone ID Related Accession (Same CDS sequence)	XM_005251343.1 , NM_001363763.2 , NM_001363763.1 , XM_011517679.1
Accession Version	NM_001363763.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 318bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-14
Organism	Homo sapiens(human)
Product	cyclin-dependent kinase inhibitor 2A isoform 6
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL449423.14. On May 30, 2018 this sequence version replaced XM_011517679.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BF347035.1, AA085532.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2150385, SAMN01820689 [ECO:0000348] ##Evidence-Data-END##

ATGATGATGG GCAGCGCCCG AGTGGCGGAG CTGCTGCTGC TCCACGGCGC GGAGCCCAAC 
TGCGCCGACC CCGCCACTCT CACCCGACCC GTGCACGACG CTGCCCGGGA GGGCTTCCTG 
GACACGCTGG TGGTGCTGCA CCGGGCCGGG GCGCGGCTGG ACGTGCGCGA TGCCTGGGGC 
CGTCTGCCCG TGGACCTGGC TGAGGAGCTG GGCCATCGCG ATGTCGCACG GTACCTGCGC 
GCGGCTGCGG GGGGCACCAG AGGCAGTAAC CATGCCCGCA TAGATGCCGC GGAAGGTCCC 
TCAGACATCC CCGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001350692.1
CDS	227..544
Translation	MMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGGTRGSNHARIDAAEGPSDIPD

Target ORF information:

RefSeq Version	NM_001363763.1
Organism	Homo sapiens(human)
Definition	Homo sapiens cyclin dependent kinase inhibitor 2A (CDKN2A), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001363763.1

ORF Insert Sequence:

ATGATGATGG GCAGCGCCCG AGTGGCGGAG CTGCTGCTGC TCCACGGCGC GGAGCCCAAC 
TGCGCCGACC CCGCCACTCT CACCCGACCC GTGCACGACG CTGCCCGGGA GGGCTTCCTG 
GACACGCTGG TGGTGCTGCA CCGGGCCGGG GCGCGGCTGG ACGTGCGCGA TGCCTGGGGC 
CGTCTGCCCG TGGACCTGGC TGAGGAGCTG GGCCATCGCG ATGTCGCACG GTACCTGCGC 
GCGGCTGCGG GGGGCACCAG AGGCAGTAAC CATGCCCGCA TAGATGCCGC GGAAGGTCCC 
TCAGACATCC CCGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDKN2A ( XM_005251343.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_005251400.1 Homo sapiens cyclin dependent kinase inhibitor 2A (CDKN2A), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu42655
Clone ID Related Accession (Same CDS sequence)	XM_005251343.1 , NM_001363763.2 , NM_001363763.1 , XM_011517679.1
Accession Version	XM_005251343.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 318bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	cyclin-dependent kinase inhibitor 2A isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGATGG GCAGCGCCCG AGTGGCGGAG CTGCTGCTGC TCCACGGCGC GGAGCCCAAC 
TGCGCCGACC CCGCCACTCT CACCCGACCC GTGCACGACG CTGCCCGGGA GGGCTTCCTG 
GACACGCTGG TGGTGCTGCA CCGGGCCGGG GCGCGGCTGG ACGTGCGCGA TGCCTGGGGC 
CGTCTGCCCG TGGACCTGGC TGAGGAGCTG GGCCATCGCG ATGTCGCACG GTACCTGCGC 
GCGGCTGCGG GGGGCACCAG AGGCAGTAAC CATGCCCGCA TAGATGCCGC GGAAGGTCCC 
TCAGACATCC CCGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005251400.1
CDS	76..393
Translation	MMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGGTRGSNHARIDAAEGPSDIPD

Target ORF information:

RefSeq Version	XM_005251343.1
Organism	Homo sapiens(human)
Definition	Homo sapiens cyclin dependent kinase inhibitor 2A (CDKN2A), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005251343.1

ORF Insert Sequence:

ATGATGATGG GCAGCGCCCG AGTGGCGGAG CTGCTGCTGC TCCACGGCGC GGAGCCCAAC 
TGCGCCGACC CCGCCACTCT CACCCGACCC GTGCACGACG CTGCCCGGGA GGGCTTCCTG 
GACACGCTGG TGGTGCTGCA CCGGGCCGGG GCGCGGCTGG ACGTGCGCGA TGCCTGGGGC 
CGTCTGCCCG TGGACCTGGC TGAGGAGCTG GGCCATCGCG ATGTCGCACG GTACCTGCGC 
GCGGCTGCGG GGGGCACCAG AGGCAGTAAC CATGCCCGCA TAGATGCCGC GGAAGGTCCC 
TCAGACATCC CCGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDKN2A ( XM_011517679.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011515981.1 Homo sapiens cyclin-dependent kinase inhibitor 2A (CDKN2A), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OHu42655
Clone ID Related Accession (Same CDS sequence)	XM_005251343.1 , NM_001363763.2 , NM_001363763.1 , XM_011517679.1
Accession Version	XM_011517679.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 318bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	cyclin-dependent kinase inhibitor 2A isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGATGG GCAGCGCCCG AGTGGCGGAG CTGCTGCTGC TCCACGGCGC GGAGCCCAAC 
TGCGCCGACC CCGCCACTCT CACCCGACCC GTGCACGACG CTGCCCGGGA GGGCTTCCTG 
GACACGCTGG TGGTGCTGCA CCGGGCCGGG GCGCGGCTGG ACGTGCGCGA TGCCTGGGGC 
CGTCTGCCCG TGGACCTGGC TGAGGAGCTG GGCCATCGCG ATGTCGCACG GTACCTGCGC 
GCGGCTGCGG GGGGCACCAG AGGCAGTAAC CATGCCCGCA TAGATGCCGC GGAAGGTCCC 
TCAGACATCC CCGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011515981.1
CDS	227..544
Translation	MMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGGTRGSNHARIDAAEGPSDIPD

Target ORF information:

RefSeq Version	XM_011517679.1
Organism	Homo sapiens(human)
Definition	Homo sapiens cyclin-dependent kinase inhibitor 2A (CDKN2A), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011517679.1

ORF Insert Sequence:

ATGATGATGG GCAGCGCCCG AGTGGCGGAG CTGCTGCTGC TCCACGGCGC GGAGCCCAAC 
TGCGCCGACC CCGCCACTCT CACCCGACCC GTGCACGACG CTGCCCGGGA GGGCTTCCTG 
GACACGCTGG TGGTGCTGCA CCGGGCCGGG GCGCGGCTGG ACGTGCGCGA TGCCTGGGGC 
CGTCTGCCCG TGGACCTGGC TGAGGAGCTG GGCCATCGCG ATGTCGCACG GTACCTGCGC 
GCGGCTGCGG GGGGCACCAG AGGCAGTAAC CATGCCCGCA TAGATGCCGC GGAAGGTCCC 
TCAGACATCC CCGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gene Symbol	CDKN2A
Entrez Gene ID	1029
Full Name	cyclin dependent kinase inhibitor 2A
Synonyms	ARF,CDK4I,CDKN2,CMM2,INK4,INK4A,MLM,MTS-1,MTS1,P14,P14ARF,P16,P16-INK4A,P16INK4,P16INK4A,P19,P19ARF,TP16
General protein information	Preferred Names cyclin dependent kinase inhibitor 2A Names cyclin-dependent kinase inhibitor 2A CDK4 inhibitor p16-INK4 alternative reading frame cell cycle negative regulator beta cyclin-dependent kinase 4 inhibitor A cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) multiple tumor suppressor 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 9 Map Location: 9p21.3
Summary	This gene generates several transcript variants which differ in their first exons. At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase. The remaining transcript includes an alternate first exon located 20 Kb upstream of the remainder of the gene; this transcript contains an alternate open reading frame (ARF) that specifies a protein which is structurally unrelated to the products of the other variants. This ARF product functions as a stabilizer of the tumor suppressor protein p53 as it can interact with, and sequester, the E3 ubiquitin-protein ligase MDM2, a protein responsible for the degradation of p53. In spite of the structural and functional differences, the CDK inhibitor isoforms and the ARF product encoded by this gene, through the regulatory roles of CDK4 and p53 in cell cycle G1 progression, share a common functionality in cell cycle G1 control. This gene is frequently mutated or deleted in a wide variety of tumors, and is known to be an important tumor suppressor gene. [provided by RefSeq, Sep 2012].
Disorder MIM:	600160
Disorder Html:	{Melanoma, cutaneous malignant, 2}, 155601 (3); Melanoma and neural system tumor syndrome, 155755 (3); Pancreatic cancer/melanoma syndrome, 606719 (3); Orolaryngeal cancer, multiple, (3)

	LOC709988	XP_001098554.1
Danio rerio (zebrafish)	LOC100329528	XP_002660514.1
Xenopus tropicalis (tropical clawed frog)	cdkn2b	NP_001006920.1
Canis lupus familiaris (dog)	CDKN2A	XP_003431646.2
Pan troglodytes (chimpanzee)	CDKN2A	NP_001139762.1
Bos taurus (cattle)	CDKN2A	XP_002689593.3
Mus musculus (house mouse)	Cdkn2a	NP_001035744.1
Rattus norvegicus (Norway rat)	Cdkn2a	NP_113738.1
Homo sapiens (human)	CDKN2A	NP_000068.1

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

CDKN2A cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

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