SMNDC1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SMNDC1
Entrez Gene ID	10285
Full Name	survival motor neuron domain containing 1
Synonyms	SMNR,SPF30,TDRD16C
General protein information	Preferred Names survival motor neuron domain containing 1 Names survival of motor neuron-related-splicing factor 30 30 kDa splicing factor SMNrp SMN-related protein splicing factor 30, survival of motor neuron-related survival motor neuron domain-containing protein 1 tudor domain containing 16C
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 10 Map Location: 10q25.2
Summary	This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. The protein encoded by this gene is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene. [provided by RefSeq, Jul 2008].
Disorder MIM:	603519

mRNA and Protein(s)

mRNA	Protein	Name
NM_005871.3	NP_005862.1	survival of motor neuron-related-splicing factor 30
NM_005871.4	NP_005862.1	survival of motor neuron-related-splicing factor 30
XM_005269382.3	XP_005269439.1	survival of motor neuron-related-splicing factor 30 isoform X1

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	smndc1	NP_997766.1
Homo sapiens (human)	SMNDC1	NP_005862.1
	SMNDC1	XP_001085864.1
Mus musculus (house mouse)	Smndc1	NP_766017.1
Xenopus tropicalis (tropical clawed frog)	smndc1	NP_001006857.1
Canis lupus familiaris (dog)	SMNDC1	XP_535011.2
Pan troglodytes (chimpanzee)	SMNDC1	XP_001142419.1
Drosophila melanogaster (fruit fly)	CG17454	NP_001138001.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006247	XP_316313.2
Bos taurus (cattle)	SMNDC1	NP_001030414.1
Rattus norvegicus (Norway rat)	Smndc1	NP_001030311.1
Gallus gallus (chicken)	SMNDC1	XP_421753.2

Gene Ontology
Bibliography

Related articles in PubMed

Fragile X mental retardation protein recognizes a G quadruplex structure within the survival motor neuron domain containing 1 mRNA 5'-UTR.
McAninch DS, Heinaman AM, Lang CN, Moss KR, Bassell GJ, Rita Mihailescu M, Evans TL
Molecular bioSystems13(8)1448-1457(2017 Jul)

Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across ethnic populations.
Yang SK, Hong M, Zhao W, Jung Y, Baek J, Tayebi N, Kim KM, Ye BD, Kim KJ, Park SH, Lee I, Lee EJ, Kim WH, Cheon JH, Kim YH, Jang BI, Kim HS, Choi JH, Koo JS, Lee JH, Jung SA, Lee YJ, Jang JY, Shin HD, Kang D, Youn HS, Liu J, Song K
Gut63(1)80-7(2014 Jan)

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW
Cell149(6)1393-406(2012 Jun)

Dynamic protein-protein interaction wiring of the human spliceosome.
Hegele A, Kamburov A, Grossmann A, Sourlis C, Wowro S, Weimann M, Will CL, Pena V, L?hrmann R, Stelzl U
Molecular cell45(4)567-80(2012 Feb)

Crystal structure of TDRD3 and methyl-arginine binding characterization of TDRD3, SMN and SPF30.
Liu K, Guo Y, Liu H, Bian C, Lam R, Liu Y, Mackenzie F, Rojas LA, Reinberg D, Bedford MT, Xu RM, Min J
PloS one7(2)e30375(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The binding specificity and affinity of the Tudor domains of TDRD3, SMN and SPF30 proteins were characterized quantitatively.
Title: Crystal structure of TDRD3 and methyl-arginine binding characterization of TDRD3, SMN and SPF30.

The structures of SMN and SPF30 Tudor domains bound to symmetric and asymmetric dimethylated arginine (DMA) are presented.
Title: Structural basis for dimethylarginine recognition by the Tudor domains of human SMN and SPF30 proteins.

U2AF35 and hPrp3 interactions with SPF30 can occur simultaneously, thereby potentially linking 3' splice site recognition with tri-small nuclear ribonucleoprotein addition
Title: Splicing factor SPF30 bridges an interaction between the prespliceosome protein U2AF35 and tri-small nuclear ribonucleoprotein protein hPrp3.

Observational study of gene-disease association. (HuGE Navigator)
Title: A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.

The following SMNDC1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SMNDC1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu19036	NM_005871.4 Latest version!	Homo sapiens survival motor neuron domain containing 1 (SMNDC1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu43918	XM_005269382.3 Latest version!	Homo sapiens survival motor neuron domain containing 1 (SMNDC1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu19036	NM_005871.3	Homo sapiens survival motor neuron domain containing 1 (SMNDC1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SMNDC1 ( NM_005871.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_005862.1 Homo sapiens survival motor neuron domain containing 1 (SMNDC1), mRNA.

Price & Availability↑

CloneID	OHu19036
Clone ID Related Accession (Same CDS sequence)	NM_005871.3 , NM_005871.4
Accession Version	NM_005871.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 717bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-17
Organism	Homo sapiens(human)
Product	survival of motor neuron-related-splicing factor 30
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BQ694303.1 and BC011234.1. This sequence is a reference standard in the RefSeqGene project. On Jun 27, 2008 this sequence version replaced NM_005871.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC011234.1, SRR1163655.469350.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCAGAGG ATTTAGCAAA GCAGCTGGCA AGCTACAAAG CTCAGCTCCA GCAAGTTGAA 
GCTGCATTAT CTGGAAATGG AGAAAATGAA GATTTGCTAA AATTGAAGAA AGATTTACAA 
GAAGTTATAG AACTAACCAA AGACCTTCTG TCAACTCAAC CTTCTGAGAC GCTTGCAAGT 
TCAGACAGTT TTGCTTCTAC TCAACCTACT CATTCATGGA AAGTAGGAGA CAAGTGTATG 
GCAGTCTGGA GTGAAGATGG ACAGTGTTAT GAAGCGGAGA TTGAGGAGAT AGATGAAGAA 
AATGGCACCG CTGCAATCAC CTTTGCTGGT TATGGCAATG CTGAAGTGAC TCCACTGTTG 
AACCTCAAGC CTGTAGAAGA AGGAAGGAAG GCAAAGGAGG ACAGTGGCAA CAAACCCATG 
TCAAAAAAAG AAATGATTGC CCAGCAGCGT GAATATAAAA AGAAGAAAGC TTTGAAAAAA 
GCTCAGAGAA TAAAAGAACT TGAGCAGGAA AGAGAGGACC AGAAAGTGAA ATGGCAACAA 
TTCAACAACA GAGCCTATTC TAAAAACAAA AAAGGCCAGG TAAAGAGGAG TATTTTTGCT 
TCACCTGAGA GTGTGACTGG TAAAGTTGGA GTAGGAACCT GTGGAATTGC TGATAAACCT 
ATGACACAAT ATCAAGATAC CTCTAAATAC AATGTCAGGC ATTTGATGCC TCAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005862.1
CDS	203..919
Translation	MSEDLAKQLASYKAQLQQVEAALSGNGENEDLLKLKKDLQEVIELTKDLLSTQPSETLASSDSFASTQPTHSWKVGDKCMAVWSEDGQCYEAEIEEIDEENGTAAITFAGYGNAEVTPLLNLKPVEEGRKAKEDSGNKPMSKKEMIAQQREYKKKKALKKAQRIKELEQEREDQKVKWQQFNNRAYSKNKKGQVKRSIFASPESVTGKVGVGTCGIADKPMTQYQDTSKYNVRHLMPQ

Target ORF information:

RefSeq Version	NM_005871.3
Organism	Homo sapiens(human)
Definition	Homo sapiens survival motor neuron domain containing 1 (SMNDC1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005871.3

ORF Insert Sequence:

ATGTCAGAGG ATTTAGCAAA GCAGCTGGCA AGCTACAAAG CTCAGCTCCA GCAAGTTGAA 
GCTGCATTAT CTGGAAATGG AGAAAATGAA GATTTGCTAA AATTGAAGAA AGATTTACAA 
GAAGTTATAG AACTAACCAA AGACCTTCTG TCAACTCAAC CTTCTGAGAC GCTTGCAAGT 
TCAGACAGTT TTGCTTCTAC TCAACCTACT CATTCATGGA AAGTAGGAGA CAAGTGTATG 
GCAGTCTGGA GTGAAGATGG ACAGTGTTAT GAAGCGGAGA TTGAGGAGAT AGATGAAGAA 
AATGGCACCG CTGCAATCAC CTTTGCTGGT TATGGCAATG CTGAAGTGAC TCCACTGTTG 
AACCTCAAGC CTGTAGAAGA AGGAAGGAAG GCAAAGGAGG ACAGTGGCAA CAAACCCATG 
TCAAAAAAAG AAATGATTGC CCAGCAGCGT GAATATAAAA AGAAGAAAGC TTTGAAAAAA 
GCTCAGAGAA TAAAAGAACT TGAGCAGGAA AGAGAGGACC AGAAAGTGAA ATGGCAACAA 
TTCAACAACA GAGCCTATTC TAAAAACAAA AAAGGCCAGG TAAAGAGGAG TATTTTTGCT 
TCACCTGAGA GTGTGACTGG TAAAGTTGGA GTAGGAACCT GTGGAATTGC TGATAAACCT 
ATGACACAAT ATCAAGATAC CTCTAAATAC AATGTCAGGC ATTTGATGCC TCAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SMNDC1 ( NM_005871.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_005862.1 Homo sapiens survival motor neuron domain containing 1 (SMNDC1), mRNA.

Price & Availability↑

CloneID	OHu19036
Clone ID Related Accession (Same CDS sequence)	NM_005871.3 , NM_005871.4
Accession Version	NM_005871.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 717bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	survival of motor neuron-related-splicing factor 30
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BQ694303.1, BC011234.1 and AL360182.15. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_005871.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.162975.1, SRR1803613.40257.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000369603.10/ ENSP00000358616.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTCAGAGG ATTTAGCAAA GCAGCTGGCA AGCTACAAAG CTCAGCTCCA GCAAGTTGAA 
GCTGCATTAT CTGGAAATGG AGAAAATGAA GATTTGCTAA AATTGAAGAA AGATTTACAA 
GAAGTTATAG AACTAACCAA AGACCTTCTG TCAACTCAAC CTTCTGAGAC GCTTGCAAGT 
TCAGACAGTT TTGCTTCTAC TCAACCTACT CATTCATGGA AAGTAGGAGA CAAGTGTATG 
GCAGTCTGGA GTGAAGATGG ACAGTGTTAT GAAGCGGAGA TTGAGGAGAT AGATGAAGAA 
AATGGCACCG CTGCAATCAC CTTTGCTGGT TATGGCAATG CTGAAGTGAC TCCACTGTTG 
AACCTCAAGC CTGTAGAAGA AGGAAGGAAG GCAAAGGAGG ACAGTGGCAA CAAACCCATG 
TCAAAAAAAG AAATGATTGC CCAGCAGCGT GAATATAAAA AGAAGAAAGC TTTGAAAAAA 
GCTCAGAGAA TAAAAGAACT TGAGCAGGAA AGAGAGGACC AGAAAGTGAA ATGGCAACAA 
TTCAACAACA GAGCCTATTC TAAAAACAAA AAAGGCCAGG TAAAGAGGAG TATTTTTGCT 
TCACCTGAGA GTGTGACTGG TAAAGTTGGA GTAGGAACCT GTGGAATTGC TGATAAACCT 
ATGACACAAT ATCAAGATAC CTCTAAATAC AATGTCAGGC ATTTGATGCC TCAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005862.1
CDS	174..890
Translation	MSEDLAKQLASYKAQLQQVEAALSGNGENEDLLKLKKDLQEVIELTKDLLSTQPSETLASSDSFASTQPTHSWKVGDKCMAVWSEDGQCYEAEIEEIDEENGTAAITFAGYGNAEVTPLLNLKPVEEGRKAKEDSGNKPMSKKEMIAQQREYKKKKALKKAQRIKELEQEREDQKVKWQQFNNRAYSKNKKGQVKRSIFASPESVTGKVGVGTCGIADKPMTQYQDTSKYNVRHLMPQ

Target ORF information:

RefSeq Version	NM_005871.4
Organism	Homo sapiens(human)
Definition	Homo sapiens survival motor neuron domain containing 1 (SMNDC1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005871.4

ORF Insert Sequence:

ATGTCAGAGG ATTTAGCAAA GCAGCTGGCA AGCTACAAAG CTCAGCTCCA GCAAGTTGAA 
GCTGCATTAT CTGGAAATGG AGAAAATGAA GATTTGCTAA AATTGAAGAA AGATTTACAA 
GAAGTTATAG AACTAACCAA AGACCTTCTG TCAACTCAAC CTTCTGAGAC GCTTGCAAGT 
TCAGACAGTT TTGCTTCTAC TCAACCTACT CATTCATGGA AAGTAGGAGA CAAGTGTATG 
GCAGTCTGGA GTGAAGATGG ACAGTGTTAT GAAGCGGAGA TTGAGGAGAT AGATGAAGAA 
AATGGCACCG CTGCAATCAC CTTTGCTGGT TATGGCAATG CTGAAGTGAC TCCACTGTTG 
AACCTCAAGC CTGTAGAAGA AGGAAGGAAG GCAAAGGAGG ACAGTGGCAA CAAACCCATG 
TCAAAAAAAG AAATGATTGC CCAGCAGCGT GAATATAAAA AGAAGAAAGC TTTGAAAAAA 
GCTCAGAGAA TAAAAGAACT TGAGCAGGAA AGAGAGGACC AGAAAGTGAA ATGGCAACAA 
TTCAACAACA GAGCCTATTC TAAAAACAAA AAAGGCCAGG TAAAGAGGAG TATTTTTGCT 
TCACCTGAGA GTGTGACTGG TAAAGTTGGA GTAGGAACCT GTGGAATTGC TGATAAACCT 
ATGACACAAT ATCAAGATAC CTCTAAATAC AATGTCAGGC ATTTGATGCC TCAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SMNDC1 ( XM_005269382.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005269439.1 Homo sapiens survival motor neuron domain containing 1 (SMNDC1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu43918
Clone ID Related Accession (Same CDS sequence)	XM_005269382.3
Accession Version	XM_005269382.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 600bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	survival of motor neuron-related-splicing factor 30 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000010.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005269382.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAAGTTA TAGAACTAAC CAAAGACCTT CTGTCAACTC AACCTTCTGA GACGCTTGCA 
AGTTCAGACA GTTTTGCTTC TACTCAACCT ACTCATTCAT GGAAAGTAGG AGACAAGTGT 
ATGGCAGTCT GGAGTGAAGA TGGACAGTGT TATGAAGCGG AGATTGAGGA GATAGATGAA 
GAAAATGGCA CCGCTGCAAT CACCTTTGCT GGTTATGGCA ATGCTGAAGT GACTCCACTG 
TTGAACCTCA AGCCTGTAGA AGAAGGAAGG AAGGCAAAGG AGGACAGTGG CAACAAACCC 
ATGTCAAAAA AAGAAATGAT TGCCCAGCAG CGTGAATATA AAAAGAAGAA AGCTTTGAAA 
AAAGCTCAGA GAATAAAAGA ACTTGAGCAG GAAAGAGAGG ACCAGAAAGT GAAATGGCAA 
CAATTCAACA ACAGAGCCTA TTCTAAAAAC AAAAAAGGCC AGGTAAAGAG GAGTATTTTT 
GCTTCACCTG AGAGTGTGAC TGGTAAAGTT GGAGTAGGAA CCTGTGGAAT TGCTGATAAA 
CCTATGACAC AATATCAAGA TACCTCTAAA TACAATGTCA GGCATTTGAT GCCTCAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005269439.1
CDS	530..1129
Translation	MEVIELTKDLLSTQPSETLASSDSFASTQPTHSWKVGDKCMAVWSEDGQCYEAEIEEIDEENGTAAITFAGYGNAEVTPLLNLKPVEEGRKAKEDSGNKPMSKKEMIAQQREYKKKKALKKAQRIKELEQEREDQKVKWQQFNNRAYSKNKKGQVKRSIFASPESVTGKVGVGTCGIADKPMTQYQDTSKYNVRHLMPQ

Target ORF information:

RefSeq Version	XM_005269382.3
Organism	Homo sapiens(human)
Definition	Homo sapiens survival motor neuron domain containing 1 (SMNDC1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005269382.3

ORF Insert Sequence:

ATGGAAGTTA TAGAACTAAC CAAAGACCTT CTGTCAACTC AACCTTCTGA GACGCTTGCA 
AGTTCAGACA GTTTTGCTTC TACTCAACCT ACTCATTCAT GGAAAGTAGG AGACAAGTGT 
ATGGCAGTCT GGAGTGAAGA TGGACAGTGT TATGAAGCGG AGATTGAGGA GATAGATGAA 
GAAAATGGCA CCGCTGCAAT CACCTTTGCT GGTTATGGCA ATGCTGAAGT GACTCCACTG 
TTGAACCTCA AGCCTGTAGA AGAAGGAAGG AAGGCAAAGG AGGACAGTGG CAACAAACCC 
ATGTCAAAAA AAGAAATGAT TGCCCAGCAG CGTGAATATA AAAAGAAGAA AGCTTTGAAA 
AAAGCTCAGA GAATAAAAGA ACTTGAGCAG GAAAGAGAGG ACCAGAAAGT GAAATGGCAA 
CAATTCAACA ACAGAGCCTA TTCTAAAAAC AAAAAAGGCC AGGTAAAGAG GAGTATTTTT 
GCTTCACCTG AGAGTGTGAC TGGTAAAGTT GGAGTAGGAA CCTGTGGAAT TGCTGATAAA 
CCTATGACAC AATATCAAGA TACCTCTAAA TACAATGTCA GGCATTTGAT GCCTCAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Fragile X mental retardation protein recognizes a G quadruplex structure within the survival motor neuron domain containing 1 mRNA 5'-UTR.
Molecular bioSystems13(8)1448-1457(2017 Jul)
McAninch DS,Heinaman AM,Lang CN,Moss KR,Bassell GJ,Rita Mihailescu M,Evans TL

Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across ethnic populations.
Gut63(1)80-7(2014 Jan)
Yang SK,Hong M,Zhao W,Jung Y,Baek J,Tayebi N,Kim KM,Ye BD,Kim KJ,Park SH,Lee I,Lee EJ,Kim WH,Cheon JH,Kim YH,Jang BI,Kim HS,Choi JH,Koo JS,Lee JH,Jung SA,Lee YJ,Jang JY,Shin HD,Kang D,Youn HS,Liu J,Song K

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Cell149(6)1393-406(2012 Jun)
Castello A,Fischer B,Eichelbaum K,Horos R,Beckmann BM,Strein C,Davey NE,Humphreys DT,Preiss T,Steinmetz LM,Krijgsveld J,Hentze MW

Dynamic protein-protein interaction wiring of the human spliceosome.
Molecular cell45(4)567-80(2012 Feb)
Hegele A,Kamburov A,Grossmann A,Sourlis C,Wowro S,Weimann M,Will CL,Pena V,L?hrmann R,Stelzl U

Crystal structure of TDRD3 and methyl-arginine binding characterization of TDRD3, SMN and SPF30.
PloS one7(2)e30375(2012)
Liu K,Guo Y,Liu H,Bian C,Lam R,Liu Y,Mackenzie F,Rojas LA,Reinberg D,Bedford MT,Xu RM,Min J

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SMNDC1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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