POP7 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	POP7
Entrez Gene ID	10248
Full Name	POP7 homolog, ribonuclease P/MRP subunit
Synonyms	0610037N12Rik,RPP2,RPP20
General protein information	Preferred Names POP7 homolog, ribonuclease P/MRP subunit Names ribonuclease P protein subunit p20 POP7 (processing of precursor, S. cerevisiae) homolog RNaseP protein p20 hPOP7 processing of precursor 7, ribonuclease P subunit processing of precursor 7, ribonuclease P/MRP subunit ribonucleases P/MRP protein subunit POP7 homolog
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7q22.1
Disorder MIM:	606113

mRNA and Protein(s)

mRNA	Protein	Name
NM_005837.2	NP_005828.2	ribonuclease P protein subunit p20
NM_005837.3	NP_005828.2	ribonuclease P protein subunit p20

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Pop7	NP_083029.1
Drosophila melanogaster (fruit fly)	Rpp20	NP_001027078.1
Homo sapiens (human)	POP7	NP_005828.2
Canis lupus familiaris (dog)	POP7	XP_005621087.1
Pan troglodytes (chimpanzee)	POP7	XP_001152640.1
	POP7	XP_001105052.1
Bos taurus (cattle)	POP7	NP_001069950.1
Rattus norvegicus (Norway rat)	Pop7	NP_001099388.1
Danio rerio (zebrafish)	pop7	NP_001006004.1

Gene Ontology
Bibliography

Related articles in PubMed

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz AG, Munschauer M, Schwanh?usser B, Vasile A, Murakawa Y, Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E, Bonneau R, Selbach M, Dieterich C, Landthaler M
Molecular cell46(5)674-90(2012 Jun)

Heterodimerization of the human RNase P/MRP subunits Rpp20 and Rpp25 is a prerequisite for interaction with the P3 arm of RNase MRP RNA.
Hands-Taylor KL, Martino L, Tata R, Babon JJ, Bui TT, Drake AF, Beavil RL, Pruijn GJ, Brown PR, Conte MR
Nucleic acids research38(12)4052-66(2010 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

analyses of interactions with deletion mutant proteins indicate that the Alba-type core domain of both Rpp20 and Rpp25 contains most of the determinants for mutual association and P3 RNA recognition.
Title: Heterodimerization of the human RNase P/MRP subunits Rpp20 and Rpp25 is a prerequisite for interaction with the P3 arm of RNase MRP RNA.

The following POP7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the POP7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu31119	NM_005837.3 Latest version!	Homo sapiens POP7 homolog, ribonuclease P/MRP subunit (POP7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu31119	NM_005837.2	Homo sapiens POP7 homolog, ribonuclease P/MRP subunit (POP7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

POP7 ( NM_005837.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_005828.2 Homo sapiens POP7 homolog, ribonuclease P/MRP subunit (POP7), mRNA.

Price & Availability↑

CloneID	OHu31119
Clone ID Related Accession (Same CDS sequence)	NM_005837.2 , NM_005837.3
Accession Version	NM_005837.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 423bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	ribonuclease P protein subunit p20
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI666854.1, BC001430.2 and AJ572668.1. On Jul 25, 2007 this sequence version replaced NM_005837.1. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.92980.1, SRR1163658.274937.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGCAGAAA ACCGAGAGCC CCGCGGTGCT GTGGAGGCTG AACTGGATCC AGTGGAATAC 
ACCCTTAGGA AAAGGCTTCC CAGCCGCCTG CCCCGGAGAC CCAATGACAT TTATGTCAAC 
ATGAAGACGG ACTTTAAGGC CCAGCTGGCC CGCTGCCAGA AGCTGCTGGA CGGAGGGGCC 
CGGGGTCAGA ACGCGTGCTC TGAGATCTAC ATTCACGGCT TGGGCCTGGC CATCAACCGC 
GCCATCAACA TCGCGCTGCA GCTGCAGGCG GGCAGCTTCG GGTCCTTGCA GGTGGCTGCC 
AATACCTCCA CCGTGGAGCT TGTTGATGAG CTGGAGCCAG AGACCGACAC ACGGGAGCCA 
CTGACTCGGA TCCGCAACAA CTCAGCCATC CACATCCGAG TCTTCAGGGT CACACCCAAG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005828.2
CDS	263..685
Translation	MAENREPRGAVEAELDPVEYTLRKRLPSRLPRRPNDIYVNMKTDFKAQLARCQKLLDGGARGQNACSEIYIHGLGLAINRAINIALQLQAGSFGSLQVAANTSTVELVDELEPETDTREPLTRIRNNSAIHIRVFRVTPK

Target ORF information:

RefSeq Version	NM_005837.2
Organism	Homo sapiens(human)
Definition	Homo sapiens POP7 homolog, ribonuclease P/MRP subunit (POP7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005837.2

ORF Insert Sequence:

ATGGCAGAAA ACCGAGAGCC CCGCGGTGCT GTGGAGGCTG AACTGGATCC AGTGGAATAC 
ACCCTTAGGA AAAGGCTTCC CAGCCGCCTG CCCCGGAGAC CCAATGACAT TTATGTCAAC 
ATGAAGACGG ACTTTAAGGC CCAGCTGGCC CGCTGCCAGA AGCTGCTGGA CGGAGGGGCC 
CGGGGTCAGA ACGCGTGCTC TGAGATCTAC ATTCACGGCT TGGGCCTGGC CATCAACCGC 
GCCATCAACA TCGCGCTGCA GCTGCAGGCG GGCAGCTTCG GGTCCTTGCA GGTGGCTGCC 
AATACCTCCA CCGTGGAGCT TGTTGATGAG CTGGAGCCAG AGACCGACAC ACGGGAGCCA 
CTGACTCGGA TCCGCAACAA CTCAGCCATC CACATCCGAG TCTTCAGGGT CACACCCAAG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

POP7 ( NM_005837.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_005828.2 Homo sapiens POP7 homolog, ribonuclease P/MRP subunit (POP7), mRNA.

Price & Availability↑

CloneID	OHu31119
Clone ID Related Accession (Same CDS sequence)	NM_005837.2 , NM_005837.3
Accession Version	NM_005837.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 423bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-16
Organism	Homo sapiens(human)
Product	ribonuclease P protein subunit p20
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI666854.1 and BC001430.2. On Nov 22, 2018 this sequence version replaced NM_005837.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189655.137178.1, CD048511.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000303151.5/ ENSP00000304353.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCAGAAA ACCGAGAGCC CCGCGGTGCT GTGGAGGCTG AACTGGATCC AGTGGAATAC 
ACCCTTAGGA AAAGGCTTCC CAGCCGCCTG CCCCGGAGAC CCAATGACAT TTATGTCAAC 
ATGAAGACGG ACTTTAAGGC CCAGCTGGCC CGCTGCCAGA AGCTGCTGGA CGGAGGGGCC 
CGGGGTCAGA ACGCGTGCTC TGAGATCTAC ATTCACGGCT TGGGCCTGGC CATCAACCGC 
GCCATCAACA TCGCGCTGCA GCTGCAGGCG GGCAGCTTCG GGTCCTTGCA GGTGGCTGCC 
AATACCTCCA CCGTGGAGCT TGTTGATGAG CTGGAGCCAG AGACCGACAC ACGGGAGCCA 
CTGACTCGGA TCCGCAACAA CTCAGCCATC CACATCCGAG TCTTCAGGGT CACACCCAAG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005828.2
CDS	195..617
Translation	MAENREPRGAVEAELDPVEYTLRKRLPSRLPRRPNDIYVNMKTDFKAQLARCQKLLDGGARGQNACSEIYIHGLGLAINRAINIALQLQAGSFGSLQVAANTSTVELVDELEPETDTREPLTRIRNNSAIHIRVFRVTPK

Target ORF information:

RefSeq Version	NM_005837.3
Organism	Homo sapiens(human)
Definition	Homo sapiens POP7 homolog, ribonuclease P/MRP subunit (POP7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005837.3

ORF Insert Sequence:

ATGGCAGAAA ACCGAGAGCC CCGCGGTGCT GTGGAGGCTG AACTGGATCC AGTGGAATAC 
ACCCTTAGGA AAAGGCTTCC CAGCCGCCTG CCCCGGAGAC CCAATGACAT TTATGTCAAC 
ATGAAGACGG ACTTTAAGGC CCAGCTGGCC CGCTGCCAGA AGCTGCTGGA CGGAGGGGCC 
CGGGGTCAGA ACGCGTGCTC TGAGATCTAC ATTCACGGCT TGGGCCTGGC CATCAACCGC 
GCCATCAACA TCGCGCTGCA GCTGCAGGCG GGCAGCTTCG GGTCCTTGCA GGTGGCTGCC 
AATACCTCCA CCGTGGAGCT TGTTGATGAG CTGGAGCCAG AGACCGACAC ACGGGAGCCA 
CTGACTCGGA TCCGCAACAA CTCAGCCATC CACATCCGAG TCTTCAGGGT CACACCCAAG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Molecular cell46(5)674-90(2012 Jun)
Baltz AG,Munschauer M,Schwanh?usser B,Vasile A,Murakawa Y,Schueler M,Youngs N,Penfold-Brown D,Drew K,Milek M,Wyler E,Bonneau R,Selbach M,Dieterich C,Landthaler M

Heterodimerization of the human RNase P/MRP subunits Rpp20 and Rpp25 is a prerequisite for interaction with the P3 arm of RNase MRP RNA.
Nucleic acids research38(12)4052-66(2010 Jul)
Hands-Taylor KL,Martino L,Tata R,Babon JJ,Bui TT,Drake AF,Beavil RL,Pruijn GJ,Brown PR,Conte MR

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POP7 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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