Gene Symbol | OLIG2 |
Entrez Gene ID | 10215 |
Full Name | oligodendrocyte transcription factor 2 |
Synonyms | BHLHB1,OLIGO2,PRKCBP2,RACK17,bHLHe19 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. [provided by RefSeq, Jul 2008]. |
Disorder MIM: |