SSX3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SSX3
Entrez Gene ID	10214
Full Name	SSX family member 3
Synonyms	CT5.3
General protein information	Preferred Names SSX family member 3 Names protein SSX3 Kruppel-associated box containing gene product SSX3 cancer/testis antigen 5.3 synovial sarcoma, X breakpoint 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xp11.23
Summary	The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. While some of the related SSX genes are involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas, this gene does not appear to be involved in such translocations. [provided by RefSeq, Jul 2013].
Disorder MIM:	300325

mRNA and Protein(s)

mRNA	Protein	Name
NM_021014.4	NP_066294.1	protein SSX3
NM_021014.3	NP_066294.1	protein SSX3
XM_011543885.2	XP_011542187.1	protein SSX3 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	LOC737502	XP_003954030.1
Homo sapiens (human)	SSX3	NP_066294.1

Gene Ontology
Bibliography

Related articles in PubMed

SSX2-4 expression in early-stage non-small cell lung cancer.
Greve KB, P?hl M, Olsen KE, Nielsen O, Ditzel HJ, Gjerstorff MF
Tissue antigens83(5)344-9(2014 May)

A multigene predictor of metastatic outcome in early stage hormone receptor-negative and triple-negative breast cancer.
Yau C, Esserman L, Moore DH, Waldman F, Sninsky J, Benz CC
Breast cancer research : BCR12(5)R85(2010)

The SSX gene family: characterization of 9 complete genes.
G?re AO, Wei IJ, Old LJ, Chen YT
International journal of cancer101(5)448-53(2002 Oct)

The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear protein, SSX2IP.
de Bruijn DR, dos Santos NR, Kater-Baats E, Thijssen J, van den Berk L, Stap J, Balemans M, Schepens M, Merkx G, van Kessel AG
Genes, chromosomes & cancer34(3)285-98(2002 Jul)

Heterogeneous expression of the SSX cancer/testis antigens in human melanoma lesions and cell lines.
dos Santos NR, Torensma R, de Vries TJ, Schreurs MW, de Bruijn DR, Kater-Baats E, Ruiter DJ, Adema GJ, van Muijen GN, van Kessel AG
Cancer research60(6)1654-62(2000 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

SSX2, SSX3, and SSX4 are expressed only in 3.5% early-stage non-small cell lung cancer patients.
Title: SSX2-4 expression in early-stage non-small cell lung cancer.

The following SSX3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SSX3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu20972	NM_021014.4 Latest version!	Homo sapiens SSX family member 3 (SSX3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu53987	XM_011543885.2 Latest version!	Homo sapiens SSX family member 3 (SSX3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
View Old Accession Versions >>
OHu20972	NM_021014.3	Homo sapiens SSX family member 3 (SSX3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SSX3 ( NM_021014.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_066294.1 Homo sapiens SSX family member 3 (SSX3), mRNA.

Price & Availability↑

CloneID	OHu20972
Clone ID Related Accession (Same CDS sequence)	NM_021014.4 , NM_021014.3
Accession Version	NM_021014.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 567bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	protein SSX3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC103862.1, U90840.1, AA609599.1 and AL606490.15. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_021014.3. ##Evidence-Data-START## Transcript exon combination :: U90840.1, BC103862.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000298396.7/ ENSP00000298396.2 RefSeq Select criteria :: based on expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAACGGAG ATGACACCTT TGCAAGGAGA CCCACGGTTG GTGCTCAAAT ACCAGAGAAG 
ATACAAAAGG CCTTCGATGA TATTGCCAAA TACTTCTCTA AGGAAGAGTG GGAAAAGATG 
AAAGTCTCGG AGAAAATCGT CTATGTGTAT ATGAAGAGAA AGTATGAGGC CATGACTAAA 
CTAGGTTTCA AGGCCATCCT CCCATCTTTC ATGCGTAATA AACGGGTCAC AGACTTCCAG 
GGGAATGATT TTGATAATGA CCCTAACCGT GGGAATCAGG TTCAACGTCC TCAGATGACT 
TTCGGCAGGC TCCAGGGAAT CTTCCCGAAG ATCATGCCCA AGAAGCCAGC AGAGGAAGGA 
AATGTTTCGA AGGAAGTGCC AGAAGCATCT GGCCCACAAA ACGATGGGAA ACAGCTGTGC 
CCCCCGGGAA AACCAACTAC CTCTGAGAAG ATTAACATGA TATCTGGACC CAAAAGGGGG 
GAACATGCCT GGACCCACAG ACTGCGTGAG AGAAAGCAGC TGGTGATTTA TGAAGAGATC 
AGCGATCCTG AGGAAGATGA TGAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_066294.1
CDS	91..657
Translation	MNGDDTFARRPTVGAQIPEKIQKAFDDIAKYFSKEEWEKMKVSEKIVYVYMKRKYEAMTKLGFKAILPSFMRNKRVTDFQGNDFDNDPNRGNQVQRPQMTFGRLQGIFPKIMPKKPAEEGNVSKEVPEASGPQNDGKQLCPPGKPTTSEKINMISGPKRGEHAWTHRLRERKQLVIYEEISDPEEDDE

Target ORF information:

RefSeq Version	NM_021014.4
Organism	Homo sapiens(human)
Definition	Homo sapiens SSX family member 3 (SSX3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021014.4

ORF Insert Sequence:

ATGAACGGAG ATGACACCTT TGCAAGGAGA CCCACGGTTG GTGCTCAAAT ACCAGAGAAG 
ATACAAAAGG CCTTCGATGA TATTGCCAAA TACTTCTCTA AGGAAGAGTG GGAAAAGATG 
AAAGTCTCGG AGAAAATCGT CTATGTGTAT ATGAAGAGAA AGTATGAGGC CATGACTAAA 
CTAGGTTTCA AGGCCATCCT CCCATCTTTC ATGCGTAATA AACGGGTCAC AGACTTCCAG 
GGGAATGATT TTGATAATGA CCCTAACCGT GGGAATCAGG TTCAACGTCC TCAGATGACT 
TTCGGCAGGC TCCAGGGAAT CTTCCCGAAG ATCATGCCCA AGAAGCCAGC AGAGGAAGGA 
AATGTTTCGA AGGAAGTGCC AGAAGCATCT GGCCCACAAA ACGATGGGAA ACAGCTGTGC 
CCCCCGGGAA AACCAACTAC CTCTGAGAAG ATTAACATGA TATCTGGACC CAAAAGGGGG 
GAACATGCCT GGACCCACAG ACTGCGTGAG AGAAAGCAGC TGGTGATTTA TGAAGAGATC 
AGCGATCCTG AGGAAGATGA TGAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SSX3 ( XM_011543885.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011542187.1 Homo sapiens SSX family member 3 (SSX3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu53987
Clone ID Related Accession (Same CDS sequence)	XM_011543885.2
Accession Version	XM_011543885.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 513bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein SSX3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011543885.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACGGAG ATGACACCTT TGCAAGGAGA CCCACGGTTG GTGCTCAAAT ACCAGAGAAG 
ATACAAAAGG CCTTCGATGA TATTGCCAAA TACTTCTCTA AGGAAGAGTG GGAAAAGATG 
AAAGTCTCGG AGAAAATCGT CTATGTGTAT ATGAAGAGAA AGTATGAGGC CATGACTAAA 
CTAGGTTTCA AGGCCATCCT CCCATCTTTC ATGCGTAATA AACGGGTCAC AGACTTCCAG 
GGGAATGATT TTGATAATGA CCCTAACCGT GGGAATCAGG TTCAACGTCC TCAGATGACT 
TTCGGCAGGC TCCAGGGAAT CTTCCCGAAG ATCATGCCCA AGAAGCCAGC AGAGGAAGGA 
AATGTTTCGA AGGAAGTGCC AGAAGCATCT GGCCCACAAA ACGATGGGAA ACAGCTGTGC 
CCCCCGGGAA AACCAACTAC CTCTGAGAAG ATTAACATGA TATCTGGTGT CCTTCAGAGA 
TACTGCAGGT TCGGTTCCAG ACCACTGCAA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011542187.1
CDS	94..606
Translation	MNGDDTFARRPTVGAQIPEKIQKAFDDIAKYFSKEEWEKMKVSEKIVYVYMKRKYEAMTKLGFKAILPSFMRNKRVTDFQGNDFDNDPNRGNQVQRPQMTFGRLQGIFPKIMPKKPAEEGNVSKEVPEASGPQNDGKQLCPPGKPTTSEKINMISGVLQRYCRFGSRPLQ

Target ORF information:

RefSeq Version	XM_011543885.2
Organism	Homo sapiens(human)
Definition	Homo sapiens SSX family member 3 (SSX3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011543885.2

ORF Insert Sequence:

ATGAACGGAG ATGACACCTT TGCAAGGAGA CCCACGGTTG GTGCTCAAAT ACCAGAGAAG 
ATACAAAAGG CCTTCGATGA TATTGCCAAA TACTTCTCTA AGGAAGAGTG GGAAAAGATG 
AAAGTCTCGG AGAAAATCGT CTATGTGTAT ATGAAGAGAA AGTATGAGGC CATGACTAAA 
CTAGGTTTCA AGGCCATCCT CCCATCTTTC ATGCGTAATA AACGGGTCAC AGACTTCCAG 
GGGAATGATT TTGATAATGA CCCTAACCGT GGGAATCAGG TTCAACGTCC TCAGATGACT 
TTCGGCAGGC TCCAGGGAAT CTTCCCGAAG ATCATGCCCA AGAAGCCAGC AGAGGAAGGA 
AATGTTTCGA AGGAAGTGCC AGAAGCATCT GGCCCACAAA ACGATGGGAA ACAGCTGTGC 
CCCCCGGGAA AACCAACTAC CTCTGAGAAG ATTAACATGA TATCTGGTGT CCTTCAGAGA 
TACTGCAGGT TCGGTTCCAG ACCACTGCAA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SSX3 ( NM_021014.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_066294.1 Homo sapiens SSX family member 3 (SSX3), mRNA.

Price & Availability↑

CloneID	OHu20972
Clone ID Related Accession (Same CDS sequence)	NM_021014.4 , NM_021014.3
Accession Version	NM_021014.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 567bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-29
Organism	Homo sapiens(human)
Product	protein SSX3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB444418.1, BC103862.1, AL606490.15, U90840.1 and AA609599.1. This sequence is a reference standard in the RefSeqGene project. On Jul 11, 2013 this sequence version replaced NM_021014.2. ##Evidence-Data-START## Transcript exon combination :: U90840.1, BC103862.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACGGAG ATGACACCTT TGCAAGGAGA CCCACGGTTG GTGCTCAAAT ACCAGAGAAG 
ATACAAAAGG CCTTCGATGA TATTGCCAAA TACTTCTCTA AGGAAGAGTG GGAAAAGATG 
AAAGTCTCGG AGAAAATCGT CTATGTGTAT ATGAAGAGAA AGTATGAGGC CATGACTAAA 
CTAGGTTTCA AGGCCATCCT CCCATCTTTC ATGCGTAATA AACGGGTCAC AGACTTCCAG 
GGGAATGATT TTGATAATGA CCCTAACCGT GGGAATCAGG TTCAACGTCC TCAGATGACT 
TTCGGCAGGC TCCAGGGAAT CTTCCCGAAG ATCATGCCCA AGAAGCCAGC AGAGGAAGGA 
AATGTTTCGA AGGAAGTGCC AGAAGCATCT GGCCCACAAA ACGATGGGAA ACAGCTGTGC 
CCCCCGGGAA AACCAACTAC CTCTGAGAAG ATTAACATGA TATCTGGACC CAAAAGGGGG 
GAACATGCCT GGACCCACAG ACTGCGTGAG AGAAAGCAGC TGGTGATTTA TGAAGAGATC 
AGCGATCCTG AGGAAGATGA TGAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_066294.1
CDS	141..707
Translation	MNGDDTFARRPTVGAQIPEKIQKAFDDIAKYFSKEEWEKMKVSEKIVYVYMKRKYEAMTKLGFKAILPSFMRNKRVTDFQGNDFDNDPNRGNQVQRPQMTFGRLQGIFPKIMPKKPAEEGNVSKEVPEASGPQNDGKQLCPPGKPTTSEKINMISGPKRGEHAWTHRLRERKQLVIYEEISDPEEDDE

Target ORF information:

RefSeq Version	NM_021014.3
Organism	Homo sapiens(human)
Definition	Homo sapiens SSX family member 3 (SSX3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021014.3

ORF Insert Sequence:

ATGAACGGAG ATGACACCTT TGCAAGGAGA CCCACGGTTG GTGCTCAAAT ACCAGAGAAG 
ATACAAAAGG CCTTCGATGA TATTGCCAAA TACTTCTCTA AGGAAGAGTG GGAAAAGATG 
AAAGTCTCGG AGAAAATCGT CTATGTGTAT ATGAAGAGAA AGTATGAGGC CATGACTAAA 
CTAGGTTTCA AGGCCATCCT CCCATCTTTC ATGCGTAATA AACGGGTCAC AGACTTCCAG 
GGGAATGATT TTGATAATGA CCCTAACCGT GGGAATCAGG TTCAACGTCC TCAGATGACT 
TTCGGCAGGC TCCAGGGAAT CTTCCCGAAG ATCATGCCCA AGAAGCCAGC AGAGGAAGGA 
AATGTTTCGA AGGAAGTGCC AGAAGCATCT GGCCCACAAA ACGATGGGAA ACAGCTGTGC 
CCCCCGGGAA AACCAACTAC CTCTGAGAAG ATTAACATGA TATCTGGACC CAAAAGGGGG 
GAACATGCCT GGACCCACAG ACTGCGTGAG AGAAAGCAGC TGGTGATTTA TGAAGAGATC 
AGCGATCCTG AGGAAGATGA TGAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

SSX2-4 expression in early-stage non-small cell lung cancer.
Tissue antigens83(5)344-9(2014 May)
Greve KB,P?hl M,Olsen KE,Nielsen O,Ditzel HJ,Gjerstorff MF

A multigene predictor of metastatic outcome in early stage hormone receptor-negative and triple-negative breast cancer.
Breast cancer research : BCR12(5)R85(2010)
Yau C,Esserman L,Moore DH,Waldman F,Sninsky J,Benz CC

The SSX gene family: characterization of 9 complete genes.
International journal of cancer101(5)448-53(2002 Oct)
G?re AO,Wei IJ,Old LJ,Chen YT

The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear protein, SSX2IP.
Genes, chromosomes & cancer34(3)285-98(2002 Jul)
de Bruijn DR,dos Santos NR,Kater-Baats E,Thijssen J,van den Berk L,Stap J,Balemans M,Schepens M,Merkx G,van Kessel AG

Heterogeneous expression of the SSX cancer/testis antigens in human melanoma lesions and cell lines.
Cancer research60(6)1654-62(2000 Mar)
dos Santos NR,Torensma R,de Vries TJ,Schreurs MW,de Bruijn DR,Kater-Baats E,Ruiter DJ,Adema GJ,van Muijen GN,van Kessel AG

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SSX3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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