CDK6 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CDK6
Entrez Gene ID	1021
Full Name	cyclin dependent kinase 6
Synonyms	MCPH12,PLSTIRE
General protein information	Preferred Names cyclin dependent kinase 6 Names cyclin-dependent kinase 6 cell division protein kinase 6 serine/threonine-protein kinase PLSTIRE
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7q21.2
Summary	The protein encoded by this gene is a member of the CMGC family of serine/threonine protein kinases. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Altered expression of this gene has been observed in multiple human cancers. A mutation in this gene resulting in reduced cell proliferation, and impaired cell motility and polarity, and has been identified in patients with primary microcephaly. [provided by RefSeq, Aug 2017].
Disorder MIM:	603368
Disorder Html:	?Microcephaly 12, primary, autosomal recessive, 616080 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001259.6	NP_001250.1	cyclin-dependent kinase 6
XM_011515731.1	XP_011514033.1	cyclin-dependent kinase 6 isoform X1
NM_001145306.1	NP_001138778.1	cyclin-dependent kinase 6
NM_001259.8	NP_001250.1	cyclin-dependent kinase 6
NM_001259.7	NP_001250.1	cyclin-dependent kinase 6
XM_006715835.1	XP_006715898.1	cyclin-dependent kinase 6 isoform X1
NM_001145306.2	NP_001138778.1	cyclin-dependent kinase 6
XM_006715835.2	XP_006715898.1	cyclin-dependent kinase 6 isoform X1

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	cdk6	NP_001137525.1
Drosophila melanogaster (fruit fly)	Cdk4	NP_725595.1
Xenopus tropicalis (tropical clawed frog)	cdk6	XP_002934637.2
	CDK6	XP_001100307.1
Canis lupus familiaris (dog)	CDK6	XP_852360.1
Bos taurus (cattle)	CDK6	NP_001179230.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP005817	XP_315841.3
Homo sapiens (human)	CDK6	NP_001138778.1
Gallus gallus (chicken)	CDK6	NP_001007893.1
Pan troglodytes (chimpanzee)	CDK6	XP_003318627.1
Mus musculus (house mouse)	Cdk6	NP_034003.1
Rattus norvegicus (Norway rat)	Cdk6	NP_001178790.1
Caenorhabditis elegans (roundworm)	cdk-4	NP_510256.1
Caenorhabditis elegans (roundworm)	cdk-4	NP_001024591.1

Gene Ontology

The following CDK6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CDK6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu23671	NM_001259.8 Latest version!	Homo sapiens cyclin dependent kinase 6 (CDK6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu23671	NM_001145306.2 Latest version!	Homo sapiens cyclin dependent kinase 6 (CDK6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu23671	XM_006715835.2 Latest version!	Homo sapiens cyclin dependent kinase 6 (CDK6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu23671	XM_011515731.1 Latest version!	Homo sapiens cyclin-dependent kinase 6 (CDK6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
View Old Accession Versions >>
OHu23671	NM_001259.6	Homo sapiens cyclin dependent kinase 6 (CDK6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu23671	NM_001259.7	Homo sapiens cyclin dependent kinase 6 (CDK6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu23671	NM_001145306.1	Homo sapiens cyclin dependent kinase 6 (CDK6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu23671	XM_006715835.1	Homo sapiens cyclin-dependent kinase 6 (CDK6), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CDK6 ( NM_001259.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_001250.1 Homo sapiens cyclin dependent kinase 6 (CDK6), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu23671
Clone ID Related Accession (Same CDS sequence)	NM_001259.6 , XM_011515731.1 , NM_001145306.1 , NM_001259.8 , NM_001259.7 , XM_006715835.1 , NM_001145306.2 , XM_006715835.2
Accession Version	NM_001259.6	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 981bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-04-16
Organism	Homo sapiens(Human)
Product	cyclin-dependent kinase 6
Comment	REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AI738486.1, BC052264.1, AC000065.1, AC005156.1, BC027989.1 and BQ773638.1. This sequence is a reference standard in the RefSeqGene project. On Feb 19, 2009 this sequence version replaced NM_001259.5. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC052264.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03267759, SAMN03267764 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGAAGG ACGGCCTGTG CCGCGCTGAC CAGCAGTACG AATGCGTGGC GGAGATCGGG 
GAGGGCGCCT ATGGGAAGGT GTTCAAGGCC CGCGACTTGA AGAACGGAGG CCGTTTCGTG 
GCGTTGAAGC GCGTGCGGGT GCAGACCGGC GAGGAGGGCA TGCCGCTCTC CACCATCCGC 
GAGGTGGCGG TGCTGAGGCA CCTGGAGACC TTCGAGCACC CCAACGTGGT CAGGTTGTTT 
GATGTGTGCA CAGTGTCACG AACAGACAGA GAAACCAAAC TAACTTTAGT GTTTGAACAT 
GTCGATCAAG ACTTGACCAC TTACTTGGAT AAAGTTCCAG AGCCTGGAGT GCCCACTGAA 
ACCATAAAGG ATATGATGTT TCAGCTTCTC CGAGGTCTGG ACTTTCTTCA TTCACACCGA 
GTAGTGCATC GCGATCTAAA ACCACAGAAC ATTCTGGTGA CCAGCAGCGG ACAAATAAAA 
CTCGCTGACT TCGGCCTTGC CCGCATCTAT AGTTTCCAGA TGGCTCTAAC CTCAGTGGTC 
GTCACGCTGT GGTACAGAGC ACCCGAAGTC TTGCTCCAGT CCAGCTACGC CACCCCCGTG 
GATCTCTGGA GTGTTGGCTG CATATTTGCA GAAATGTTTC GTAGAAAGCC TCTTTTTCGT 
GGAAGTTCAG ATGTTGATCA ACTAGGAAAA ATCTTGGACG TGATTGGACT CCCAGGAGAA 
GAAGACTGGC CTAGAGATGT TGCCCTTCCC AGGCAGGCTT TTCATTCAAA ATCTGCCCAA 
CCAATTGAGA AGTTTGTAAC AGATATCGAT GAACTAGGCA AAGACCTACT TCTGAAGTGT 
TTGACATTTA ACCCAGCCAA AAGAATATCT GCCTACAGTG CCCTGTCTCA CCCATACTTC 
CAGGACCTGG AAAGGTGCAA AGAAAACCTG GATTCCCACC TGCCGCCCAG CCAGAACACC 
TCGGAGCTGA ATACAGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001250.1
CDS	413..1393
Translation	MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLERCKENLDSHLPPSQNTSELNTA

Target ORF information:

RefSeq Version	NM_001259.6
Organism	Homo sapiens(Human)
Definition	Homo sapiens cyclin dependent kinase 6 (CDK6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001259.6

ORF Insert Sequence:

ATGGAGAAGG ACGGCCTGTG CCGCGCTGAC CAGCAGTACG AATGCGTGGC GGAGATCGGG 
GAGGGCGCCT ATGGGAAGGT GTTCAAGGCC CGCGACTTGA AGAACGGAGG CCGTTTCGTG 
GCGTTGAAGC GCGTGCGGGT GCAGACCGGC GAGGAGGGCA TGCCGCTCTC CACCATCCGC 
GAGGTGGCGG TGCTGAGGCA CCTGGAGACC TTCGAGCACC CCAACGTGGT CAGGTTGTTT 
GATGTGTGCA CAGTGTCACG AACAGACAGA GAAACCAAAC TAACTTTAGT GTTTGAACAT 
GTCGATCAAG ACTTGACCAC TTACTTGGAT AAAGTTCCAG AGCCTGGAGT GCCCACTGAA 
ACCATAAAGG ATATGATGTT TCAGCTTCTC CGAGGTCTGG ACTTTCTTCA TTCACACCGA 
GTAGTGCATC GCGATCTAAA ACCACAGAAC ATTCTGGTGA CCAGCAGCGG ACAAATAAAA 
CTCGCTGACT TCGGCCTTGC CCGCATCTAT AGTTTCCAGA TGGCTCTAAC CTCAGTGGTC 
GTCACGCTGT GGTACAGAGC ACCCGAAGTC TTGCTCCAGT CCAGCTACGC CACCCCCGTG 
GATCTCTGGA GTGTTGGCTG CATATTTGCA GAAATGTTTC GTAGAAAGCC TCTTTTTCGT 
GGAAGTTCAG ATGTTGATCA ACTAGGAAAA ATCTTGGACG TGATTGGACT CCCAGGAGAA 
GAAGACTGGC CTAGAGATGT TGCCCTTCCC AGGCAGGCTT TTCATTCAAA ATCTGCCCAA 
CCAATTGAGA AGTTTGTAAC AGATATCGAT GAACTAGGCA AAGACCTACT TCTGAAGTGT 
TTGACATTTA ACCCAGCCAA AAGAATATCT GCCTACAGTG CCCTGTCTCA CCCATACTTC 
CAGGACCTGG AAAGGTGCAA AGAAAACCTG GATTCCCACC TGCCGCCCAG CCAGAACACC 
TCGGAGCTGA ATACAGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDK6 ( NM_001145306.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001138778.1 Homo sapiens cyclin dependent kinase 6 (CDK6), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu23671
Clone ID Related Accession (Same CDS sequence)	NM_001259.6 , XM_011515731.1 , NM_001145306.1 , NM_001259.8 , NM_001259.7 , XM_006715835.1 , NM_001145306.2 , XM_006715835.2
Accession Version	NM_001145306.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 981bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-01
Organism	Homo sapiens(human)
Product	cyclin-dependent kinase 6
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AW665776.1, AK313491.1, BC052264.1, AC000065.1, AC005156.1, BC027989.1 and BQ773638.1. This sequence is a reference standard in the RefSeqGene project. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.327070.1, SRR1163655.158391.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03267764 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END##

ATGGAGAAGG ACGGCCTGTG CCGCGCTGAC CAGCAGTACG AATGCGTGGC GGAGATCGGG 
GAGGGCGCCT ATGGGAAGGT GTTCAAGGCC CGCGACTTGA AGAACGGAGG CCGTTTCGTG 
GCGTTGAAGC GCGTGCGGGT GCAGACCGGC GAGGAGGGCA TGCCGCTCTC CACCATCCGC 
GAGGTGGCGG TGCTGAGGCA CCTGGAGACC TTCGAGCACC CCAACGTGGT CAGGTTGTTT 
GATGTGTGCA CAGTGTCACG AACAGACAGA GAAACCAAAC TAACTTTAGT GTTTGAACAT 
GTCGATCAAG ACTTGACCAC TTACTTGGAT AAAGTTCCAG AGCCTGGAGT GCCCACTGAA 
ACCATAAAGG ATATGATGTT TCAGCTTCTC CGAGGTCTGG ACTTTCTTCA TTCACACCGA 
GTAGTGCATC GCGATCTAAA ACCACAGAAC ATTCTGGTGA CCAGCAGCGG ACAAATAAAA 
CTCGCTGACT TCGGCCTTGC CCGCATCTAT AGTTTCCAGA TGGCTCTAAC CTCAGTGGTC 
GTCACGCTGT GGTACAGAGC ACCCGAAGTC TTGCTCCAGT CCAGCTACGC CACCCCCGTG 
GATCTCTGGA GTGTTGGCTG CATATTTGCA GAAATGTTTC GTAGAAAGCC TCTTTTTCGT 
GGAAGTTCAG ATGTTGATCA ACTAGGAAAA ATCTTGGACG TGATTGGACT CCCAGGAGAA 
GAAGACTGGC CTAGAGATGT TGCCCTTCCC AGGCAGGCTT TTCATTCAAA ATCTGCCCAA 
CCAATTGAGA AGTTTGTAAC AGATATCGAT GAACTAGGCA AAGACCTACT TCTGAAGTGT 
TTGACATTTA ACCCAGCCAA AAGAATATCT GCCTACAGTG CCCTGTCTCA CCCATACTTC 
CAGGACCTGG AAAGGTGCAA AGAAAACCTG GATTCCCACC TGCCGCCCAG CCAGAACACC 
TCGGAGCTGA ATACAGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001138778.1
CDS	518..1498
Translation	MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLERCKENLDSHLPPSQNTSELNTA

Target ORF information:

RefSeq Version	NM_001145306.1
Organism	Homo sapiens(human)
Definition	Homo sapiens cyclin dependent kinase 6 (CDK6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145306.1

ORF Insert Sequence:

ATGGAGAAGG ACGGCCTGTG CCGCGCTGAC CAGCAGTACG AATGCGTGGC GGAGATCGGG 
GAGGGCGCCT ATGGGAAGGT GTTCAAGGCC CGCGACTTGA AGAACGGAGG CCGTTTCGTG 
GCGTTGAAGC GCGTGCGGGT GCAGACCGGC GAGGAGGGCA TGCCGCTCTC CACCATCCGC 
GAGGTGGCGG TGCTGAGGCA CCTGGAGACC TTCGAGCACC CCAACGTGGT CAGGTTGTTT 
GATGTGTGCA CAGTGTCACG AACAGACAGA GAAACCAAAC TAACTTTAGT GTTTGAACAT 
GTCGATCAAG ACTTGACCAC TTACTTGGAT AAAGTTCCAG AGCCTGGAGT GCCCACTGAA 
ACCATAAAGG ATATGATGTT TCAGCTTCTC CGAGGTCTGG ACTTTCTTCA TTCACACCGA 
GTAGTGCATC GCGATCTAAA ACCACAGAAC ATTCTGGTGA CCAGCAGCGG ACAAATAAAA 
CTCGCTGACT TCGGCCTTGC CCGCATCTAT AGTTTCCAGA TGGCTCTAAC CTCAGTGGTC 
GTCACGCTGT GGTACAGAGC ACCCGAAGTC TTGCTCCAGT CCAGCTACGC CACCCCCGTG 
GATCTCTGGA GTGTTGGCTG CATATTTGCA GAAATGTTTC GTAGAAAGCC TCTTTTTCGT 
GGAAGTTCAG ATGTTGATCA ACTAGGAAAA ATCTTGGACG TGATTGGACT CCCAGGAGAA 
GAAGACTGGC CTAGAGATGT TGCCCTTCCC AGGCAGGCTT TTCATTCAAA ATCTGCCCAA 
CCAATTGAGA AGTTTGTAAC AGATATCGAT GAACTAGGCA AAGACCTACT TCTGAAGTGT 
TTGACATTTA ACCCAGCCAA AAGAATATCT GCCTACAGTG CCCTGTCTCA CCCATACTTC 
CAGGACCTGG AAAGGTGCAA AGAAAACCTG GATTCCCACC TGCCGCCCAG CCAGAACACC 
TCGGAGCTGA ATACAGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDK6 ( NM_001259.8 ) cDNA ORF clone, Homo sapiens(human) -> NP_001250.1 Homo sapiens cyclin dependent kinase 6 (CDK6), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu23671
Clone ID Related Accession (Same CDS sequence)	NM_001259.6 , XM_011515731.1 , NM_001145306.1 , NM_001259.8 , NM_001259.7 , XM_006715835.1 , NM_001145306.2 , XM_006715835.2
Accession Version	NM_001259.8 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 981bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	cyclin-dependent kinase 6
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC004011.1, AI738486.1, BC052264.1, AC000065.1, AC005156.1, BC027989.1 and BQ773638.1. On Jun 2, 2019 this sequence version replaced NM_001259.7. Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC052264.1, SRR1163655.614437.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03267759, SAMN03267764 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGAGAAGG ACGGCCTGTG CCGCGCTGAC CAGCAGTACG AATGCGTGGC GGAGATCGGG 
GAGGGCGCCT ATGGGAAGGT GTTCAAGGCC CGCGACTTGA AGAACGGAGG CCGTTTCGTG 
GCGTTGAAGC GCGTGCGGGT GCAGACCGGC GAGGAGGGCA TGCCGCTCTC CACCATCCGC 
GAGGTGGCGG TGCTGAGGCA CCTGGAGACC TTCGAGCACC CCAACGTGGT CAGGTTGTTT 
GATGTGTGCA CAGTGTCACG AACAGACAGA GAAACCAAAC TAACTTTAGT GTTTGAACAT 
GTCGATCAAG ACTTGACCAC TTACTTGGAT AAAGTTCCAG AGCCTGGAGT GCCCACTGAA 
ACCATAAAGG ATATGATGTT TCAGCTTCTC CGAGGTCTGG ACTTTCTTCA TTCACACCGA 
GTAGTGCATC GCGATCTAAA ACCACAGAAC ATTCTGGTGA CCAGCAGCGG ACAAATAAAA 
CTCGCTGACT TCGGCCTTGC CCGCATCTAT AGTTTCCAGA TGGCTCTAAC CTCAGTGGTC 
GTCACGCTGT GGTACAGAGC ACCCGAAGTC TTGCTCCAGT CCAGCTACGC CACCCCCGTG 
GATCTCTGGA GTGTTGGCTG CATATTTGCA GAAATGTTTC GTAGAAAGCC TCTTTTTCGT 
GGAAGTTCAG ATGTTGATCA ACTAGGAAAA ATCTTGGACG TGATTGGACT CCCAGGAGAA 
GAAGACTGGC CTAGAGATGT TGCCCTTCCC AGGCAGGCTT TTCATTCAAA ATCTGCCCAA 
CCAATTGAGA AGTTTGTAAC AGATATCGAT GAACTAGGCA AAGACCTACT TCTGAAGTGT 
TTGACATTTA ACCCAGCCAA AAGAATATCT GCCTACAGTG CCCTGTCTCA CCCATACTTC 
CAGGACCTGG AAAGGTGCAA AGAAAACCTG GATTCCCACC TGCCGCCCAG CCAGAACACC 
TCGGAGCTGA ATACAGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001250.1
CDS	455..1435
Translation	MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLERCKENLDSHLPPSQNTSELNTA

Target ORF information:

RefSeq Version	NM_001259.8
Organism	Homo sapiens(human)
Definition	Homo sapiens cyclin dependent kinase 6 (CDK6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001259.8

ORF Insert Sequence:

ATGGAGAAGG ACGGCCTGTG CCGCGCTGAC CAGCAGTACG AATGCGTGGC GGAGATCGGG 
GAGGGCGCCT ATGGGAAGGT GTTCAAGGCC CGCGACTTGA AGAACGGAGG CCGTTTCGTG 
GCGTTGAAGC GCGTGCGGGT GCAGACCGGC GAGGAGGGCA TGCCGCTCTC CACCATCCGC 
GAGGTGGCGG TGCTGAGGCA CCTGGAGACC TTCGAGCACC CCAACGTGGT CAGGTTGTTT 
GATGTGTGCA CAGTGTCACG AACAGACAGA GAAACCAAAC TAACTTTAGT GTTTGAACAT 
GTCGATCAAG ACTTGACCAC TTACTTGGAT AAAGTTCCAG AGCCTGGAGT GCCCACTGAA 
ACCATAAAGG ATATGATGTT TCAGCTTCTC CGAGGTCTGG ACTTTCTTCA TTCACACCGA 
GTAGTGCATC GCGATCTAAA ACCACAGAAC ATTCTGGTGA CCAGCAGCGG ACAAATAAAA 
CTCGCTGACT TCGGCCTTGC CCGCATCTAT AGTTTCCAGA TGGCTCTAAC CTCAGTGGTC 
GTCACGCTGT GGTACAGAGC ACCCGAAGTC TTGCTCCAGT CCAGCTACGC CACCCCCGTG 
GATCTCTGGA GTGTTGGCTG CATATTTGCA GAAATGTTTC GTAGAAAGCC TCTTTTTCGT 
GGAAGTTCAG ATGTTGATCA ACTAGGAAAA ATCTTGGACG TGATTGGACT CCCAGGAGAA 
GAAGACTGGC CTAGAGATGT TGCCCTTCCC AGGCAGGCTT TTCATTCAAA ATCTGCCCAA 
CCAATTGAGA AGTTTGTAAC AGATATCGAT GAACTAGGCA AAGACCTACT TCTGAAGTGT 
TTGACATTTA ACCCAGCCAA AAGAATATCT GCCTACAGTG CCCTGTCTCA CCCATACTTC 
CAGGACCTGG AAAGGTGCAA AGAAAACCTG GATTCCCACC TGCCGCCCAG CCAGAACACC 
TCGGAGCTGA ATACAGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDK6 ( NM_001259.7 ) cDNA ORF clone, Homo sapiens(human) -> NP_001250.1 Homo sapiens cyclin dependent kinase 6 (CDK6), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu23671
Clone ID Related Accession (Same CDS sequence)	NM_001259.6 , XM_011515731.1 , NM_001145306.1 , NM_001259.8 , NM_001259.7 , XM_006715835.1 , NM_001145306.2 , XM_006715835.2
Accession Version	NM_001259.7	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 981bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-26
Organism	Homo sapiens(human)
Product	cyclin-dependent kinase 6
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC004011.1, AI738486.1, BC052264.1, AC000065.1, AC005156.1, BC027989.1 and BQ773638.1. On Aug 17, 2017 this sequence version replaced NM_001259.6. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.81785.1, BC052264.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03267759, SAMN03267764 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGAAGG ACGGCCTGTG CCGCGCTGAC CAGCAGTACG AATGCGTGGC GGAGATCGGG 
GAGGGCGCCT ATGGGAAGGT GTTCAAGGCC CGCGACTTGA AGAACGGAGG CCGTTTCGTG 
GCGTTGAAGC GCGTGCGGGT GCAGACCGGC GAGGAGGGCA TGCCGCTCTC CACCATCCGC 
GAGGTGGCGG TGCTGAGGCA CCTGGAGACC TTCGAGCACC CCAACGTGGT CAGGTTGTTT 
GATGTGTGCA CAGTGTCACG AACAGACAGA GAAACCAAAC TAACTTTAGT GTTTGAACAT 
GTCGATCAAG ACTTGACCAC TTACTTGGAT AAAGTTCCAG AGCCTGGAGT GCCCACTGAA 
ACCATAAAGG ATATGATGTT TCAGCTTCTC CGAGGTCTGG ACTTTCTTCA TTCACACCGA 
GTAGTGCATC GCGATCTAAA ACCACAGAAC ATTCTGGTGA CCAGCAGCGG ACAAATAAAA 
CTCGCTGACT TCGGCCTTGC CCGCATCTAT AGTTTCCAGA TGGCTCTAAC CTCAGTGGTC 
GTCACGCTGT GGTACAGAGC ACCCGAAGTC TTGCTCCAGT CCAGCTACGC CACCCCCGTG 
GATCTCTGGA GTGTTGGCTG CATATTTGCA GAAATGTTTC GTAGAAAGCC TCTTTTTCGT 
GGAAGTTCAG ATGTTGATCA ACTAGGAAAA ATCTTGGACG TGATTGGACT CCCAGGAGAA 
GAAGACTGGC CTAGAGATGT TGCCCTTCCC AGGCAGGCTT TTCATTCAAA ATCTGCCCAA 
CCAATTGAGA AGTTTGTAAC AGATATCGAT GAACTAGGCA AAGACCTACT TCTGAAGTGT 
TTGACATTTA ACCCAGCCAA AAGAATATCT GCCTACAGTG CCCTGTCTCA CCCATACTTC 
CAGGACCTGG AAAGGTGCAA AGAAAACCTG GATTCCCACC TGCCGCCCAG CCAGAACACC 
TCGGAGCTGA ATACAGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001250.1
CDS	446..1426
Translation	MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLERCKENLDSHLPPSQNTSELNTA

Target ORF information:

RefSeq Version	NM_001259.7
Organism	Homo sapiens(human)
Definition	Homo sapiens cyclin dependent kinase 6 (CDK6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001259.7

ORF Insert Sequence:

ATGGAGAAGG ACGGCCTGTG CCGCGCTGAC CAGCAGTACG AATGCGTGGC GGAGATCGGG 
GAGGGCGCCT ATGGGAAGGT GTTCAAGGCC CGCGACTTGA AGAACGGAGG CCGTTTCGTG 
GCGTTGAAGC GCGTGCGGGT GCAGACCGGC GAGGAGGGCA TGCCGCTCTC CACCATCCGC 
GAGGTGGCGG TGCTGAGGCA CCTGGAGACC TTCGAGCACC CCAACGTGGT CAGGTTGTTT 
GATGTGTGCA CAGTGTCACG AACAGACAGA GAAACCAAAC TAACTTTAGT GTTTGAACAT 
GTCGATCAAG ACTTGACCAC TTACTTGGAT AAAGTTCCAG AGCCTGGAGT GCCCACTGAA 
ACCATAAAGG ATATGATGTT TCAGCTTCTC CGAGGTCTGG ACTTTCTTCA TTCACACCGA 
GTAGTGCATC GCGATCTAAA ACCACAGAAC ATTCTGGTGA CCAGCAGCGG ACAAATAAAA 
CTCGCTGACT TCGGCCTTGC CCGCATCTAT AGTTTCCAGA TGGCTCTAAC CTCAGTGGTC 
GTCACGCTGT GGTACAGAGC ACCCGAAGTC TTGCTCCAGT CCAGCTACGC CACCCCCGTG 
GATCTCTGGA GTGTTGGCTG CATATTTGCA GAAATGTTTC GTAGAAAGCC TCTTTTTCGT 
GGAAGTTCAG ATGTTGATCA ACTAGGAAAA ATCTTGGACG TGATTGGACT CCCAGGAGAA 
GAAGACTGGC CTAGAGATGT TGCCCTTCCC AGGCAGGCTT TTCATTCAAA ATCTGCCCAA 
CCAATTGAGA AGTTTGTAAC AGATATCGAT GAACTAGGCA AAGACCTACT TCTGAAGTGT 
TTGACATTTA ACCCAGCCAA AAGAATATCT GCCTACAGTG CCCTGTCTCA CCCATACTTC 
CAGGACCTGG AAAGGTGCAA AGAAAACCTG GATTCCCACC TGCCGCCCAG CCAGAACACC 
TCGGAGCTGA ATACAGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDK6 ( NM_001145306.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001138778.1 Homo sapiens cyclin dependent kinase 6 (CDK6), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu23671
Clone ID Related Accession (Same CDS sequence)	NM_001259.6 , XM_011515731.1 , NM_001145306.1 , NM_001259.8 , NM_001259.7 , XM_006715835.1 , NM_001145306.2 , XM_006715835.2
Accession Version	NM_001145306.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 981bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Homo sapiens(human)
Product	cyclin-dependent kinase 6
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AW665776.1, AK313491.1, BC052264.1, AC000065.1, AC005156.1, BC027989.1 and BQ773638.1. On Nov 30, 2019 this sequence version replaced NM_001145306.1. Transcript Variant: This variant (2) represents the longer transcript. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7346977.2726814.1, AK313491.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAGAAGG ACGGCCTGTG CCGCGCTGAC CAGCAGTACG AATGCGTGGC GGAGATCGGG 
GAGGGCGCCT ATGGGAAGGT GTTCAAGGCC CGCGACTTGA AGAACGGAGG CCGTTTCGTG 
GCGTTGAAGC GCGTGCGGGT GCAGACCGGC GAGGAGGGCA TGCCGCTCTC CACCATCCGC 
GAGGTGGCGG TGCTGAGGCA CCTGGAGACC TTCGAGCACC CCAACGTGGT CAGGTTGTTT 
GATGTGTGCA CAGTGTCACG AACAGACAGA GAAACCAAAC TAACTTTAGT GTTTGAACAT 
GTCGATCAAG ACTTGACCAC TTACTTGGAT AAAGTTCCAG AGCCTGGAGT GCCCACTGAA 
ACCATAAAGG ATATGATGTT TCAGCTTCTC CGAGGTCTGG ACTTTCTTCA TTCACACCGA 
GTAGTGCATC GCGATCTAAA ACCACAGAAC ATTCTGGTGA CCAGCAGCGG ACAAATAAAA 
CTCGCTGACT TCGGCCTTGC CCGCATCTAT AGTTTCCAGA TGGCTCTAAC CTCAGTGGTC 
GTCACGCTGT GGTACAGAGC ACCCGAAGTC TTGCTCCAGT CCAGCTACGC CACCCCCGTG 
GATCTCTGGA GTGTTGGCTG CATATTTGCA GAAATGTTTC GTAGAAAGCC TCTTTTTCGT 
GGAAGTTCAG ATGTTGATCA ACTAGGAAAA ATCTTGGACG TGATTGGACT CCCAGGAGAA 
GAAGACTGGC CTAGAGATGT TGCCCTTCCC AGGCAGGCTT TTCATTCAAA ATCTGCCCAA 
CCAATTGAGA AGTTTGTAAC AGATATCGAT GAACTAGGCA AAGACCTACT TCTGAAGTGT 
TTGACATTTA ACCCAGCCAA AAGAATATCT GCCTACAGTG CCCTGTCTCA CCCATACTTC 
CAGGACCTGG AAAGGTGCAA AGAAAACCTG GATTCCCACC TGCCGCCCAG CCAGAACACC 
TCGGAGCTGA ATACAGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001138778.1
CDS	464..1444
Translation	MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLERCKENLDSHLPPSQNTSELNTA

Target ORF information:

RefSeq Version	NM_001145306.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cyclin dependent kinase 6 (CDK6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145306.2

ORF Insert Sequence:

ATGGAGAAGG ACGGCCTGTG CCGCGCTGAC CAGCAGTACG AATGCGTGGC GGAGATCGGG 
GAGGGCGCCT ATGGGAAGGT GTTCAAGGCC CGCGACTTGA AGAACGGAGG CCGTTTCGTG 
GCGTTGAAGC GCGTGCGGGT GCAGACCGGC GAGGAGGGCA TGCCGCTCTC CACCATCCGC 
GAGGTGGCGG TGCTGAGGCA CCTGGAGACC TTCGAGCACC CCAACGTGGT CAGGTTGTTT 
GATGTGTGCA CAGTGTCACG AACAGACAGA GAAACCAAAC TAACTTTAGT GTTTGAACAT 
GTCGATCAAG ACTTGACCAC TTACTTGGAT AAAGTTCCAG AGCCTGGAGT GCCCACTGAA 
ACCATAAAGG ATATGATGTT TCAGCTTCTC CGAGGTCTGG ACTTTCTTCA TTCACACCGA 
GTAGTGCATC GCGATCTAAA ACCACAGAAC ATTCTGGTGA CCAGCAGCGG ACAAATAAAA 
CTCGCTGACT TCGGCCTTGC CCGCATCTAT AGTTTCCAGA TGGCTCTAAC CTCAGTGGTC 
GTCACGCTGT GGTACAGAGC ACCCGAAGTC TTGCTCCAGT CCAGCTACGC CACCCCCGTG 
GATCTCTGGA GTGTTGGCTG CATATTTGCA GAAATGTTTC GTAGAAAGCC TCTTTTTCGT 
GGAAGTTCAG ATGTTGATCA ACTAGGAAAA ATCTTGGACG TGATTGGACT CCCAGGAGAA 
GAAGACTGGC CTAGAGATGT TGCCCTTCCC AGGCAGGCTT TTCATTCAAA ATCTGCCCAA 
CCAATTGAGA AGTTTGTAAC AGATATCGAT GAACTAGGCA AAGACCTACT TCTGAAGTGT 
TTGACATTTA ACCCAGCCAA AAGAATATCT GCCTACAGTG CCCTGTCTCA CCCATACTTC 
CAGGACCTGG AAAGGTGCAA AGAAAACCTG GATTCCCACC TGCCGCCCAG CCAGAACACC 
TCGGAGCTGA ATACAGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDK6 ( XM_011515731.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011514033.1 Homo sapiens cyclin-dependent kinase 6 (CDK6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu23671
Clone ID Related Accession (Same CDS sequence)	NM_001259.6 , XM_011515731.1 , NM_001145306.1 , NM_001259.8 , NM_001259.7 , XM_006715835.1 , NM_001145306.2 , XM_006715835.2
Accession Version	XM_011515731.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 981bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	cyclin-dependent kinase 6 isoform X1
Comment

ATGGAGAAGG ACGGCCTGTG CCGCGCTGAC CAGCAGTACG AATGCGTGGC GGAGATCGGG 
GAGGGCGCCT ATGGGAAGGT GTTCAAGGCC CGCGACTTGA AGAACGGAGG CCGTTTCGTG 
GCGTTGAAGC GCGTGCGGGT GCAGACCGGC GAGGAGGGCA TGCCGCTCTC CACCATCCGC 
GAGGTGGCGG TGCTGAGGCA CCTGGAGACC TTCGAGCACC CCAACGTGGT CAGGTTGTTT 
GATGTGTGCA CAGTGTCACG AACAGACAGA GAAACCAAAC TAACTTTAGT GTTTGAACAT 
GTCGATCAAG ACTTGACCAC TTACTTGGAT AAAGTTCCAG AGCCTGGAGT GCCCACTGAA 
ACCATAAAGG ATATGATGTT TCAGCTTCTC CGAGGTCTGG ACTTTCTTCA TTCACACCGA 
GTAGTGCATC GCGATCTAAA ACCACAGAAC ATTCTGGTGA CCAGCAGCGG ACAAATAAAA 
CTCGCTGACT TCGGCCTTGC CCGCATCTAT AGTTTCCAGA TGGCTCTAAC CTCAGTGGTC 
GTCACGCTGT GGTACAGAGC ACCCGAAGTC TTGCTCCAGT CCAGCTACGC CACCCCCGTG 
GATCTCTGGA GTGTTGGCTG CATATTTGCA GAAATGTTTC GTAGAAAGCC TCTTTTTCGT 
GGAAGTTCAG ATGTTGATCA ACTAGGAAAA ATCTTGGACG TGATTGGACT CCCAGGAGAA 
GAAGACTGGC CTAGAGATGT TGCCCTTCCC AGGCAGGCTT TTCATTCAAA ATCTGCCCAA 
CCAATTGAGA AGTTTGTAAC AGATATCGAT GAACTAGGCA AAGACCTACT TCTGAAGTGT 
TTGACATTTA ACCCAGCCAA AAGAATATCT GCCTACAGTG CCCTGTCTCA CCCATACTTC 
CAGGACCTGG AAAGGTGCAA AGAAAACCTG GATTCCCACC TGCCGCCCAG CCAGAACACC 
TCGGAGCTGA ATACAGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011514033.1
Translation	MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLERCKENLDSHLPPSQNTSELNTA

Target ORF information:

RefSeq Version	XM_011515731.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens cyclin-dependent kinase 6 (CDK6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011515731.1

ORF Insert Sequence:

ATGGAGAAGG ACGGCCTGTG CCGCGCTGAC CAGCAGTACG AATGCGTGGC GGAGATCGGG 
GAGGGCGCCT ATGGGAAGGT GTTCAAGGCC CGCGACTTGA AGAACGGAGG CCGTTTCGTG 
GCGTTGAAGC GCGTGCGGGT GCAGACCGGC GAGGAGGGCA TGCCGCTCTC CACCATCCGC 
GAGGTGGCGG TGCTGAGGCA CCTGGAGACC TTCGAGCACC CCAACGTGGT CAGGTTGTTT 
GATGTGTGCA CAGTGTCACG AACAGACAGA GAAACCAAAC TAACTTTAGT GTTTGAACAT 
GTCGATCAAG ACTTGACCAC TTACTTGGAT AAAGTTCCAG AGCCTGGAGT GCCCACTGAA 
ACCATAAAGG ATATGATGTT TCAGCTTCTC CGAGGTCTGG ACTTTCTTCA TTCACACCGA 
GTAGTGCATC GCGATCTAAA ACCACAGAAC ATTCTGGTGA CCAGCAGCGG ACAAATAAAA 
CTCGCTGACT TCGGCCTTGC CCGCATCTAT AGTTTCCAGA TGGCTCTAAC CTCAGTGGTC 
GTCACGCTGT GGTACAGAGC ACCCGAAGTC TTGCTCCAGT CCAGCTACGC CACCCCCGTG 
GATCTCTGGA GTGTTGGCTG CATATTTGCA GAAATGTTTC GTAGAAAGCC TCTTTTTCGT 
GGAAGTTCAG ATGTTGATCA ACTAGGAAAA ATCTTGGACG TGATTGGACT CCCAGGAGAA 
GAAGACTGGC CTAGAGATGT TGCCCTTCCC AGGCAGGCTT TTCATTCAAA ATCTGCCCAA 
CCAATTGAGA AGTTTGTAAC AGATATCGAT GAACTAGGCA AAGACCTACT TCTGAAGTGT 
TTGACATTTA ACCCAGCCAA AAGAATATCT GCCTACAGTG CCCTGTCTCA CCCATACTTC 
CAGGACCTGG AAAGGTGCAA AGAAAACCTG GATTCCCACC TGCCGCCCAG CCAGAACACC 
TCGGAGCTGA ATACAGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDK6 ( XM_006715835.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_006715898.1 Homo sapiens cyclin-dependent kinase 6 (CDK6), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu23671
Clone ID Related Accession (Same CDS sequence)	NM_001259.6 , XM_011515731.1 , NM_001145306.1 , NM_001259.8 , NM_001259.7 , XM_006715835.1 , NM_001145306.2 , XM_006715835.2
Accession Version	XM_006715835.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 981bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	cyclin-dependent kinase 6 isoform X1
Comment

ATGGAGAAGG ACGGCCTGTG CCGCGCTGAC CAGCAGTACG AATGCGTGGC GGAGATCGGG 
GAGGGCGCCT ATGGGAAGGT GTTCAAGGCC CGCGACTTGA AGAACGGAGG CCGTTTCGTG 
GCGTTGAAGC GCGTGCGGGT GCAGACCGGC GAGGAGGGCA TGCCGCTCTC CACCATCCGC 
GAGGTGGCGG TGCTGAGGCA CCTGGAGACC TTCGAGCACC CCAACGTGGT CAGGTTGTTT 
GATGTGTGCA CAGTGTCACG AACAGACAGA GAAACCAAAC TAACTTTAGT GTTTGAACAT 
GTCGATCAAG ACTTGACCAC TTACTTGGAT AAAGTTCCAG AGCCTGGAGT GCCCACTGAA 
ACCATAAAGG ATATGATGTT TCAGCTTCTC CGAGGTCTGG ACTTTCTTCA TTCACACCGA 
GTAGTGCATC GCGATCTAAA ACCACAGAAC ATTCTGGTGA CCAGCAGCGG ACAAATAAAA 
CTCGCTGACT TCGGCCTTGC CCGCATCTAT AGTTTCCAGA TGGCTCTAAC CTCAGTGGTC 
GTCACGCTGT GGTACAGAGC ACCCGAAGTC TTGCTCCAGT CCAGCTACGC CACCCCCGTG 
GATCTCTGGA GTGTTGGCTG CATATTTGCA GAAATGTTTC GTAGAAAGCC TCTTTTTCGT 
GGAAGTTCAG ATGTTGATCA ACTAGGAAAA ATCTTGGACG TGATTGGACT CCCAGGAGAA 
GAAGACTGGC CTAGAGATGT TGCCCTTCCC AGGCAGGCTT TTCATTCAAA ATCTGCCCAA 
CCAATTGAGA AGTTTGTAAC AGATATCGAT GAACTAGGCA AAGACCTACT TCTGAAGTGT 
TTGACATTTA ACCCAGCCAA AAGAATATCT GCCTACAGTG CCCTGTCTCA CCCATACTTC 
CAGGACCTGG AAAGGTGCAA AGAAAACCTG GATTCCCACC TGCCGCCCAG CCAGAACACC 
TCGGAGCTGA ATACAGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006715898.1
Translation	MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLERCKENLDSHLPPSQNTSELNTA

Target ORF information:

RefSeq Version	XM_006715835.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens cyclin-dependent kinase 6 (CDK6), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006715835.1

ORF Insert Sequence:

ATGGAGAAGG ACGGCCTGTG CCGCGCTGAC CAGCAGTACG AATGCGTGGC GGAGATCGGG 
GAGGGCGCCT ATGGGAAGGT GTTCAAGGCC CGCGACTTGA AGAACGGAGG CCGTTTCGTG 
GCGTTGAAGC GCGTGCGGGT GCAGACCGGC GAGGAGGGCA TGCCGCTCTC CACCATCCGC 
GAGGTGGCGG TGCTGAGGCA CCTGGAGACC TTCGAGCACC CCAACGTGGT CAGGTTGTTT 
GATGTGTGCA CAGTGTCACG AACAGACAGA GAAACCAAAC TAACTTTAGT GTTTGAACAT 
GTCGATCAAG ACTTGACCAC TTACTTGGAT AAAGTTCCAG AGCCTGGAGT GCCCACTGAA 
ACCATAAAGG ATATGATGTT TCAGCTTCTC CGAGGTCTGG ACTTTCTTCA TTCACACCGA 
GTAGTGCATC GCGATCTAAA ACCACAGAAC ATTCTGGTGA CCAGCAGCGG ACAAATAAAA 
CTCGCTGACT TCGGCCTTGC CCGCATCTAT AGTTTCCAGA TGGCTCTAAC CTCAGTGGTC 
GTCACGCTGT GGTACAGAGC ACCCGAAGTC TTGCTCCAGT CCAGCTACGC CACCCCCGTG 
GATCTCTGGA GTGTTGGCTG CATATTTGCA GAAATGTTTC GTAGAAAGCC TCTTTTTCGT 
GGAAGTTCAG ATGTTGATCA ACTAGGAAAA ATCTTGGACG TGATTGGACT CCCAGGAGAA 
GAAGACTGGC CTAGAGATGT TGCCCTTCCC AGGCAGGCTT TTCATTCAAA ATCTGCCCAA 
CCAATTGAGA AGTTTGTAAC AGATATCGAT GAACTAGGCA AAGACCTACT TCTGAAGTGT 
TTGACATTTA ACCCAGCCAA AAGAATATCT GCCTACAGTG CCCTGTCTCA CCCATACTTC 
CAGGACCTGG AAAGGTGCAA AGAAAACCTG GATTCCCACC TGCCGCCCAG CCAGAACACC 
TCGGAGCTGA ATACAGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDK6 ( XM_006715835.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_006715898.1 Homo sapiens cyclin dependent kinase 6 (CDK6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu23671
Clone ID Related Accession (Same CDS sequence)	NM_001259.6 , XM_011515731.1 , NM_001145306.1 , NM_001259.8 , NM_001259.7 , XM_006715835.1 , NM_001145306.2 , XM_006715835.2
Accession Version	XM_006715835.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 981bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	cyclin-dependent kinase 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006715835.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGAAGG ACGGCCTGTG CCGCGCTGAC CAGCAGTACG AATGCGTGGC GGAGATCGGG 
GAGGGCGCCT ATGGGAAGGT GTTCAAGGCC CGCGACTTGA AGAACGGAGG CCGTTTCGTG 
GCGTTGAAGC GCGTGCGGGT GCAGACCGGC GAGGAGGGCA TGCCGCTCTC CACCATCCGC 
GAGGTGGCGG TGCTGAGGCA CCTGGAGACC TTCGAGCACC CCAACGTGGT CAGGTTGTTT 
GATGTGTGCA CAGTGTCACG AACAGACAGA GAAACCAAAC TAACTTTAGT GTTTGAACAT 
GTCGATCAAG ACTTGACCAC TTACTTGGAT AAAGTTCCAG AGCCTGGAGT GCCCACTGAA 
ACCATAAAGG ATATGATGTT TCAGCTTCTC CGAGGTCTGG ACTTTCTTCA TTCACACCGA 
GTAGTGCATC GCGATCTAAA ACCACAGAAC ATTCTGGTGA CCAGCAGCGG ACAAATAAAA 
CTCGCTGACT TCGGCCTTGC CCGCATCTAT AGTTTCCAGA TGGCTCTAAC CTCAGTGGTC 
GTCACGCTGT GGTACAGAGC ACCCGAAGTC TTGCTCCAGT CCAGCTACGC CACCCCCGTG 
GATCTCTGGA GTGTTGGCTG CATATTTGCA GAAATGTTTC GTAGAAAGCC TCTTTTTCGT 
GGAAGTTCAG ATGTTGATCA ACTAGGAAAA ATCTTGGACG TGATTGGACT CCCAGGAGAA 
GAAGACTGGC CTAGAGATGT TGCCCTTCCC AGGCAGGCTT TTCATTCAAA ATCTGCCCAA 
CCAATTGAGA AGTTTGTAAC AGATATCGAT GAACTAGGCA AAGACCTACT TCTGAAGTGT 
TTGACATTTA ACCCAGCCAA AAGAATATCT GCCTACAGTG CCCTGTCTCA CCCATACTTC 
CAGGACCTGG AAAGGTGCAA AGAAAACCTG GATTCCCACC TGCCGCCCAG CCAGAACACC 
TCGGAGCTGA ATACAGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006715898.1
CDS	638..1618
Translation	MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLERCKENLDSHLPPSQNTSELNTA

Target ORF information:

RefSeq Version	XM_006715835.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cyclin dependent kinase 6 (CDK6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006715835.2

ORF Insert Sequence:

ATGGAGAAGG ACGGCCTGTG CCGCGCTGAC CAGCAGTACG AATGCGTGGC GGAGATCGGG 
GAGGGCGCCT ATGGGAAGGT GTTCAAGGCC CGCGACTTGA AGAACGGAGG CCGTTTCGTG 
GCGTTGAAGC GCGTGCGGGT GCAGACCGGC GAGGAGGGCA TGCCGCTCTC CACCATCCGC 
GAGGTGGCGG TGCTGAGGCA CCTGGAGACC TTCGAGCACC CCAACGTGGT CAGGTTGTTT 
GATGTGTGCA CAGTGTCACG AACAGACAGA GAAACCAAAC TAACTTTAGT GTTTGAACAT 
GTCGATCAAG ACTTGACCAC TTACTTGGAT AAAGTTCCAG AGCCTGGAGT GCCCACTGAA 
ACCATAAAGG ATATGATGTT TCAGCTTCTC CGAGGTCTGG ACTTTCTTCA TTCACACCGA 
GTAGTGCATC GCGATCTAAA ACCACAGAAC ATTCTGGTGA CCAGCAGCGG ACAAATAAAA 
CTCGCTGACT TCGGCCTTGC CCGCATCTAT AGTTTCCAGA TGGCTCTAAC CTCAGTGGTC 
GTCACGCTGT GGTACAGAGC ACCCGAAGTC TTGCTCCAGT CCAGCTACGC CACCCCCGTG 
GATCTCTGGA GTGTTGGCTG CATATTTGCA GAAATGTTTC GTAGAAAGCC TCTTTTTCGT 
GGAAGTTCAG ATGTTGATCA ACTAGGAAAA ATCTTGGACG TGATTGGACT CCCAGGAGAA 
GAAGACTGGC CTAGAGATGT TGCCCTTCCC AGGCAGGCTT TTCATTCAAA ATCTGCCCAA 
CCAATTGAGA AGTTTGTAAC AGATATCGAT GAACTAGGCA AAGACCTACT TCTGAAGTGT 
TTGACATTTA ACCCAGCCAA AAGAATATCT GCCTACAGTG CCCTGTCTCA CCCATACTTC 
CAGGACCTGG AAAGGTGCAA AGAAAACCTG GATTCCCACC TGCCGCCCAG CCAGAACACC 
TCGGAGCTGA ATACAGCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

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CDK6 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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FAX

オンラインフォーム

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