Gene Symbol | DHRS9 |
Entrez Gene ID | 10170 |
Full Name | dehydrogenase/reductase 9 |
Synonyms | 3-alpha-HSD,3ALPHA-HSD,RDH-E2,RDH-TBE,RDH15,RDHL,RDHTBE,RETSDR8,SDR9C4 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. This protein demonstrates oxidoreductase activity toward hydroxysteroids and is able to convert 3-alpha-tetrahydroprogesterone to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone in the cytoplasm, and may additionally function as a transcriptional repressor in the nucleus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]. |
Disorder MIM: |