DPP3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	DPP3
Entrez Gene ID	10072
Full Name	dipeptidyl peptidase 3
Synonyms	DPPIII
General protein information	Preferred Names dipeptidyl peptidase 3 Names dipeptidyl peptidase 3 DPP III dipeptidyl aminopeptidase III dipeptidyl arylamidase III dipeptidyl peptidase III enkephalinase B
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11q13.2
Summary	This gene encodes a protein that is a member of the M49 family of metallopeptidases. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH) and has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Increased activity of this protein is associated with endometrial and ovarian cancers. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2012].
Disorder MIM:	606818

mRNA and Protein(s)

mRNA	Protein	Name
NM_005700.4	NP_005691.2	dipeptidyl peptidase 3 isoform 1
NM_001256670.1	NP_001243599.1	dipeptidyl peptidase 3 isoform 2
NM_130443.4	NP_569710.2	dipeptidyl peptidase 3 isoform 1
NM_130443.3	NP_569710.2	dipeptidyl peptidase 3 isoform 1
NM_005700.5	NP_005691.2	dipeptidyl peptidase 3 isoform 1
NM_001256670.2	NP_001243599.1	dipeptidyl peptidase 3 isoform 2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	DPP3	XP_003313214.1
	DPP3	XP_001118008.2
Bos taurus (cattle)	DPP3	NP_001019684.2
Neurospora crassa	NCU02701	XP_965474.2
Rattus norvegicus (Norway rat)	Dpp3	NP_446200.1
Drosophila melanogaster (fruit fly)	DppIII	NP_731237.1
Saccharomyces cerevisiae (baker's yeast)	YOL057W	NP_014584.1
Canis lupus familiaris (dog)	DPP3	XP_005631490.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004394	XP_313678.4
Eremothecium gossypii	AGOS_AER229C	NP_985086.1
Magnaporthe oryzae (rice blast fungus)	MGG_04445	XP_003713540.1
Xenopus tropicalis (tropical clawed frog)	dpp3	XP_004913745.1
Homo sapiens (human)	DPP3	NP_005691.2
Mus musculus (house mouse)	Dpp3	NP_598564.2
Danio rerio (zebrafish)	dpp3	NP_001002683.1
Caenorhabditis elegans (roundworm)	CELE_F02E9.9	NP_001040648.2
Kluyveromyces lactis	KLLA0C04059g	XP_452378.1

Gene Ontology
Bibliography

Related articles in PubMed

Identification of dipeptidyl peptidase 3 as the Angiotensin-(1-7) degrading peptidase in human HK-2 renal epithelial cells.
Cruz-Diaz N, Wilson BA, Pirro NT, Brosnihan KB, Marshall AC, Chappell MC
Peptides8329-37(2016 Sep)

Human dipeptidyl peptidase III regulates G-protein coupled receptor-dependent Ca2+ concentration in human embryonic kidney 293T cells.
Prajapati SC, Singh R, Chauhan SS
Biological chemistry397(6)563-9(2016 Jun)

Human dipeptidyl peptidase III mRNA variant I and II are expressed concurrently in multiple tumor derived cell lines and translated at comparable efficiency in vitro.
Prajapati SC, Chauhan SS
Molecular biology reports43(6)457-62(2016 Jun)

Substrate complexes of human dipeptidyl peptidase III reveal the mechanism of enzyme inhibition.
Kumar P, Reithofer V, Reisinger M, Wallner S, Pavkov-Keller T, Macheroux P, Gruber K
Scientific reports623787(2016 Mar)

Molecular simulations reveal that the long range fluctuations of human DPP III change upon ligand binding.
Tomi? A, Berynskyy M, Wade RC, Tomi? S
Molecular bioSystems11(11)3068-80(2015 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

We conclude that DPP 3 may influence the cellular expression of Ang-(1-7) and potentially reflect a therapeutic target to augment the actions of the peptide
Title: Identification of dipeptidyl peptidase 3 as the Angiotensin-(1-7) degrading peptidase in human HK-2 renal epithelial cells.

biological function of human dipeptidyl peptidase III
Title: Human dipeptidyl peptidase III regulates G-protein coupled receptor-dependent Ca2+ concentration in human embryonic kidney 293T cells.

Evidence for concurrent expression of hDPP III mRNA V-I and V-II in multiple human tumor derived cell lines.
Title: Human dipeptidyl peptidase III mRNA variant I and II are expressed concurrently in multiple tumor derived cell lines and translated at comparable efficiency in vitro.

several crystal structures of complexes of human dipeptidyl peptidase III with different peptides.
Title: Substrate complexes of human dipeptidyl peptidase III reveal the mechanism of enzyme inhibition.

the DPP III conformational landscape and the influence of ligand binding on the protein structure and dynamics, was investigated.
Title: Molecular simulations reveal that the long range fluctuations of human DPP III change upon ligand binding.

The following DPP3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DPP3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu26674	NM_130443.4 Latest version!	Homo sapiens dipeptidyl peptidase 3 (DPP3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu26674	NM_005700.5 Latest version!	Homo sapiens dipeptidyl peptidase 3 (DPP3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu26862	NM_001256670.2 Latest version!	Homo sapiens dipeptidyl peptidase 3 (DPP3), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
View Old Accession Versions >>
OHu26674	NM_130443.3	Homo sapiens dipeptidyl peptidase 3 (DPP3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu26674	NM_005700.4	Homo sapiens dipeptidyl peptidase 3 (DPP3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu26862	NM_001256670.1	Homo sapiens dipeptidyl peptidase 3 (DPP3), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

DPP3 ( NM_005700.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_005691.2 Homo sapiens dipeptidyl peptidase 3 (DPP3), transcript variant 1, mRNA.

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CloneID	OHu26674
Clone ID Related Accession (Same CDS sequence)	NM_005700.4 , NM_130443.4 , NM_130443.3 , NM_005700.5
Accession Version	NM_005700.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2214bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	dipeptidyl peptidase 3 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC403406.1, DC325853.1, DC407885.1, AK315478.1, AJ271216.1 and CD366941.1. On Feb 15, 2012 this sequence version replaced NM_005700.3. Transcript Variant: This variant (1) encodes the longer isoform (1). Variants 1 and 2 encode the same isoform. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AL833475.1, BC007221.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: lack of evidence for use of upstream AUG ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGACA CCCAGTACAT CCTGCCCAAT GACATCGGCG TGTCTAGCCT GGACTGCCGT 
GAGGCCTTCC GCCTGCTGTC ACCCACAGAG CGCCTCTATG CCTACCACCT GTCCCGTGCC 
GCCTGGTACG GAGGCCTGGC TGTGCTGCTT CAGACCTCCC CTGAGGCCCC CTACATCTAT 
GCTCTGCTCA GCCGCCTCTT CCGCGCCCAG GACCCCGACC AGCTGCGCCA ACATGCCCTG 
GCTGAAGGCC TTACCGAGGA GGAGTATCAG GCGTTCCTGG TCTATGCCGC GGGTGTTTAC 
TCCAACATGG GCAACTACAA GTCCTTTGGT GACACCAAGT TTGTTCCCAA CTTGCCCAAG 
GAAAAGCTGG AACGGGTGAT CCTAGGGAGT GAGGCTGCTC AGCAGCACCC AGAAGAAGTC 
AGGGGCCTCT GGCAGACCTG CGGGGAGCTT ATGTTCTCTC TGGAGCCAAG GCTTCGACAC 
CTCGGACTGG GGAAGGAGGG AATCACCACC TATTTCTCTG GGAATTGTAC CATGGAAGAT 
GCCAAATTGG CCCAGGACTT TCTGGACTCA CAGAACCTCA GTGCCTACAA CACCCGGCTC 
TTCAAAGAGG TCGATGGAGA AGGGAAGCCC TACTACGAGG TGCGGCTGGC TTCTGTGCTT 
GGCTCAGAGC CTTCCCTGGA CTCTGAGGTG ACTTCCAAGC TGAAGAGCTA TGAATTCCGG 
GGAAGCCCTT TCCAGGTGAC CCGGGGGGAC TACGCGCCCA TCCTCCAGAA GGTGGTGGAG 
CAGCTGGAGA AAGCCAAGGC CTATGCAGCC AACAGCCACC AGGGGCAGAT GCTGGCCCAG 
TATATAGAGA GCTTCACCCA GGGCTCCATC GAGGCCCACA AGAGGGGCTC CCGCTTCTGG 
ATCCAGGACA AAGGCCCCAT CGTGGAGAGT TACATCGGGT TCATCGAGAG CTACCGCGAC 
CCCTTTGGTT CCCGAGGAGA ATTTGAAGGT TTCGTAGCTG TGGTGAACAA GGCCATGAGT 
GCCAAGTTTG AGCGGCTGGT GGCGAGCGCA GAGCAGCTGC TGAAGGAGCT GCCCTGGCCC 
CCAACCTTTG AGAAGGACAA GTTCCTCACC CCTGACTTCA CCTCCCTGGA TGTTCTCACC 
TTCGCTGGCT CCGGCATCCC TGCCGGCATC AACATCCCCA ACTACGATGA TCTGAGGCAG 
ACGGAAGGCT TTAAGAACGT GTCGCTGGGG AATGTGCTGG CTGTGGCCTA CGCCACGCAG 
CGGGAGAAGC TTACCTTTCT GGAGGAGGAT GACAAGGACC TGTACATCCT CTGGAAGGGG 
CCCTCCTTCG ATGTGCAGGT GGGCCTGCAC GAGCTGCTGG GCCATGGCAG TGGCAAGCTC 
TTCGTACAGG ACGAAAAAGG AGCATTCAAC TTTGACCAGG AAACAGTGAT CAACCCAGAG 
ACGGGCGAGC AGATTCAGAG CTGGTATCGG AGCGGGGAGA CCTGGGATAG CAAGTTCAGC 
ACCATCGCCT CCAGCTACGA AGAGTGCCGG GCTGAGAGCG TGGGTCTCTA CCTCTGTCTC 
CACCCGCAAG TGCTGGAGAT CTTTGGCTTT GAGGGGGCTG ATGCGGAGGA CGTGATCTAC 
GTGAACTGGC TCAACATGGT TCGGGCCGGG CTGCTCGCTC TGGAGTTCTA CACACCTGAG 
GCCTTCAACT GGCGACAGGC CCATATGCAG GCCCGGTTTG TGATCCTGAG AGTCTTGCTG 
GAGGCTGGCG AGGGACTCGT TACCATCACT CCCACCACAG GCTCCGATGG GCGCCCAGAT 
GCCCGGGTCC GCCTCGACCG CAGCAAGATC CGGTCTGTGG GCAAGCCTGC TCTAGAGCGC 
TTCCTGCGGA GACTTCAGGT GCTGAAGTCC ACAGGGGATG TGGCCGGAGG GCGGGCCCTG 
TACGAGGGGT ATGCAACAGT CACTGATGCG CCCCCCGAGT GCTTCCTCAC CCTCAGGGAC 
ACGGTGCTGC TGCGTAAGGA ATCTCGGAAG CTCATTGTTC AGCCCAACAC TCGCCTTGAA 
GGCTCAGACG TGCAGCTTCT GGAATACGAG GCGTCAGCTG CTGGCCTCAT CCGATCCTTC 
TCTGAGCGTT TCCCAGAGGA TGGACCCGAG TTGGAGGAGA TCCTCACACA GCTGGCCACA 
GCCGATGCCC GATTCTGGAA GGGCCCCAGT GAGGCCCCAT CTGGCCAAGC TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005691.2
CDS	459..2672
Translation	MADTQYILPNDIGVSSLDCREAFRLLSPTERLYAYHLSRAAWYGGLAVLLQTSPEAPYIYALLSRLFRAQDPDQLRQHALAEGLTEEEYQAFLVYAAGVYSNMGNYKSFGDTKFVPNLPKEKLERVILGSEAAQQHPEEVRGLWQTCGELMFSLEPRLRHLGLGKEGITTYFSGNCTMEDAKLAQDFLDSQNLSAYNTRLFKEVDGEGKPYYEVRLASVLGSEPSLDSEVTSKLKSYEFRGSPFQVTRGDYAPILQKVVEQLEKAKAYAANSHQGQMLAQYIESFTQGSIEAHKRGSRFWIQDKGPIVESYIGFIESYRDPFGSRGEFEGFVAVVNKAMSAKFERLVASAEQLLKELPWPPTFEKDKFLTPDFTSLDVLTFAGSGIPAGINIPNYDDLRQTEGFKNVSLGNVLAVAYATQREKLTFLEEDDKDLYILWKGPSFDVQVGLHELLGHGSGKLFVQDEKGAFNFDQETVINPETGEQIQSWYRSGETWDSKFSTIASSYEECRAESVGLYLCLHPQVLEIFGFEGADAEDVIYVNWLNMVRAGLLALEFYTPEAFNWRQAHMQARFVILRVLLEAGEGLVTITPTTGSDGRPDARVRLDRSKIRSVGKPALERFLRRLQVLKSTGDVAGGRALYEGYATVTDAPPECFLTLRDTVLLRKESRKLIVQPNTRLEGSDVQLLEYEASAAGLIRSFSERFPEDGPELEEILTQLATADARFWKGPSEAPSGQA

Target ORF information:

RefSeq Version	NM_005700.4
Organism	Homo sapiens(human)
Definition	Homo sapiens dipeptidyl peptidase 3 (DPP3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005700.4

ORF Insert Sequence:

ATGGCGGACA CCCAGTACAT CCTGCCCAAT GACATCGGCG TGTCTAGCCT GGACTGCCGT 
GAGGCCTTCC GCCTGCTGTC ACCCACAGAG CGCCTCTATG CCTACCACCT GTCCCGTGCC 
GCCTGGTACG GAGGCCTGGC TGTGCTGCTT CAGACCTCCC CTGAGGCCCC CTACATCTAT 
GCTCTGCTCA GCCGCCTCTT CCGCGCCCAG GACCCCGACC AGCTGCGCCA ACATGCCCTG 
GCTGAAGGCC TTACCGAGGA GGAGTATCAG GCGTTCCTGG TCTATGCCGC GGGTGTTTAC 
TCCAACATGG GCAACTACAA GTCCTTTGGT GACACCAAGT TTGTTCCCAA CTTGCCCAAG 
GAAAAGCTGG AACGGGTGAT CCTAGGGAGT GAGGCTGCTC AGCAGCACCC AGAAGAAGTC 
AGGGGCCTCT GGCAGACCTG CGGGGAGCTT ATGTTCTCTC TGGAGCCAAG GCTTCGACAC 
CTCGGACTGG GGAAGGAGGG AATCACCACC TATTTCTCTG GGAATTGTAC CATGGAAGAT 
GCCAAATTGG CCCAGGACTT TCTGGACTCA CAGAACCTCA GTGCCTACAA CACCCGGCTC 
TTCAAAGAGG TCGATGGAGA AGGGAAGCCC TACTACGAGG TGCGGCTGGC TTCTGTGCTT 
GGCTCAGAGC CTTCCCTGGA CTCTGAGGTG ACTTCCAAGC TGAAGAGCTA TGAATTCCGG 
GGAAGCCCTT TCCAGGTGAC CCGGGGGGAC TACGCGCCCA TCCTCCAGAA GGTGGTGGAG 
CAGCTGGAGA AAGCCAAGGC CTATGCAGCC AACAGCCACC AGGGGCAGAT GCTGGCCCAG 
TATATAGAGA GCTTCACCCA GGGCTCCATC GAGGCCCACA AGAGGGGCTC CCGCTTCTGG 
ATCCAGGACA AAGGCCCCAT CGTGGAGAGT TACATCGGGT TCATCGAGAG CTACCGCGAC 
CCCTTTGGTT CCCGAGGAGA ATTTGAAGGT TTCGTAGCTG TGGTGAACAA GGCCATGAGT 
GCCAAGTTTG AGCGGCTGGT GGCGAGCGCA GAGCAGCTGC TGAAGGAGCT GCCCTGGCCC 
CCAACCTTTG AGAAGGACAA GTTCCTCACC CCTGACTTCA CCTCCCTGGA TGTTCTCACC 
TTCGCTGGCT CCGGCATCCC TGCCGGCATC AACATCCCCA ACTACGATGA TCTGAGGCAG 
ACGGAAGGCT TTAAGAACGT GTCGCTGGGG AATGTGCTGG CTGTGGCCTA CGCCACGCAG 
CGGGAGAAGC TTACCTTTCT GGAGGAGGAT GACAAGGACC TGTACATCCT CTGGAAGGGG 
CCCTCCTTCG ATGTGCAGGT GGGCCTGCAC GAGCTGCTGG GCCATGGCAG TGGCAAGCTC 
TTCGTACAGG ACGAAAAAGG AGCATTCAAC TTTGACCAGG AAACAGTGAT CAACCCAGAG 
ACGGGCGAGC AGATTCAGAG CTGGTATCGG AGCGGGGAGA CCTGGGATAG CAAGTTCAGC 
ACCATCGCCT CCAGCTACGA AGAGTGCCGG GCTGAGAGCG TGGGTCTCTA CCTCTGTCTC 
CACCCGCAAG TGCTGGAGAT CTTTGGCTTT GAGGGGGCTG ATGCGGAGGA CGTGATCTAC 
GTGAACTGGC TCAACATGGT TCGGGCCGGG CTGCTCGCTC TGGAGTTCTA CACACCTGAG 
GCCTTCAACT GGCGACAGGC CCATATGCAG GCCCGGTTTG TGATCCTGAG AGTCTTGCTG 
GAGGCTGGCG AGGGACTCGT TACCATCACT CCCACCACAG GCTCCGATGG GCGCCCAGAT 
GCCCGGGTCC GCCTCGACCG CAGCAAGATC CGGTCTGTGG GCAAGCCTGC TCTAGAGCGC 
TTCCTGCGGA GACTTCAGGT GCTGAAGTCC ACAGGGGATG TGGCCGGAGG GCGGGCCCTG 
TACGAGGGGT ATGCAACAGT CACTGATGCG CCCCCCGAGT GCTTCCTCAC CCTCAGGGAC 
ACGGTGCTGC TGCGTAAGGA ATCTCGGAAG CTCATTGTTC AGCCCAACAC TCGCCTTGAA 
GGCTCAGACG TGCAGCTTCT GGAATACGAG GCGTCAGCTG CTGGCCTCAT CCGATCCTTC 
TCTGAGCGTT TCCCAGAGGA TGGACCCGAG TTGGAGGAGA TCCTCACACA GCTGGCCACA 
GCCGATGCCC GATTCTGGAA GGGCCCCAGT GAGGCCCCAT CTGGCCAAGC TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DPP3 ( NM_130443.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_569710.2 Homo sapiens dipeptidyl peptidase 3 (DPP3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu26674
Clone ID Related Accession (Same CDS sequence)	NM_005700.4 , NM_130443.4 , NM_130443.3 , NM_005700.5
Accession Version	NM_130443.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2214bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Homo sapiens(human)
Product	dipeptidyl peptidase 3 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC407885.1, BC024271.1, AL833475.1 and CD366941.1. This sequence is a reference standard in the RefSeqGene project. On Jun 3, 2019 this sequence version replaced NM_130443.3. Transcript Variant: This variant (2) uses an alternate acceptor splice site at a 5' non-coding exon compared to variant 1. Variants 1 and 2 encode the same isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK222566.1, AJ271216.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGACA CCCAGTACAT CCTGCCCAAT GACATCGGCG TGTCTAGCCT GGACTGCCGT 
GAGGCCTTCC GCCTGCTGTC ACCCACAGAG CGCCTCTATG CCTACCACCT GTCCCGTGCC 
GCCTGGTACG GAGGCCTGGC TGTGCTGCTT CAGACCTCCC CTGAGGCCCC CTACATCTAT 
GCTCTGCTCA GCCGCCTCTT CCGCGCCCAG GACCCCGACC AGCTGCGCCA ACATGCCCTG 
GCTGAAGGCC TTACCGAGGA GGAGTATCAG GCGTTCCTGG TCTATGCCGC GGGTGTTTAC 
TCCAACATGG GCAACTACAA GTCCTTTGGT GACACCAAGT TTGTTCCCAA CTTGCCCAAG 
GAAAAGCTGG AACGGGTGAT CCTAGGGAGT GAGGCTGCTC AGCAGCACCC AGAAGAAGTC 
AGGGGCCTCT GGCAGACCTG CGGGGAGCTT ATGTTCTCTC TGGAGCCAAG GCTTCGACAC 
CTCGGACTGG GGAAGGAGGG AATCACCACC TATTTCTCTG GGAATTGTAC CATGGAAGAT 
GCCAAATTGG CCCAGGACTT TCTGGACTCA CAGAACCTCA GTGCCTACAA CACCCGGCTC 
TTCAAAGAGG TCGATGGAGA AGGGAAGCCC TACTACGAGG TGCGGCTGGC TTCTGTGCTT 
GGCTCAGAGC CTTCCCTGGA CTCTGAGGTG ACTTCCAAGC TGAAGAGCTA TGAATTCCGG 
GGAAGCCCTT TCCAGGTGAC CCGGGGGGAC TACGCGCCCA TCCTCCAGAA GGTGGTGGAG 
CAGCTGGAGA AAGCCAAGGC CTATGCAGCC AACAGCCACC AGGGGCAGAT GCTGGCCCAG 
TATATAGAGA GCTTCACCCA GGGCTCCATC GAGGCCCACA AGAGGGGCTC CCGCTTCTGG 
ATCCAGGACA AAGGCCCCAT CGTGGAGAGT TACATCGGGT TCATCGAGAG CTACCGCGAC 
CCCTTTGGTT CCCGAGGAGA ATTTGAAGGT TTCGTAGCTG TGGTGAACAA GGCCATGAGT 
GCCAAGTTTG AGCGGCTGGT GGCGAGCGCA GAGCAGCTGC TGAAGGAGCT GCCCTGGCCC 
CCAACCTTTG AGAAGGACAA GTTCCTCACC CCTGACTTCA CCTCCCTGGA TGTTCTCACC 
TTCGCTGGCT CCGGCATCCC TGCCGGCATC AACATCCCCA ACTACGATGA TCTGAGGCAG 
ACGGAAGGCT TTAAGAACGT GTCGCTGGGG AATGTGCTGG CTGTGGCCTA CGCCACGCAG 
CGGGAGAAGC TTACCTTTCT GGAGGAGGAT GACAAGGACC TGTACATCCT CTGGAAGGGG 
CCCTCCTTCG ATGTGCAGGT GGGCCTGCAC GAGCTGCTGG GCCATGGCAG TGGCAAGCTC 
TTCGTACAGG ACGAAAAAGG AGCATTCAAC TTTGACCAGG AAACAGTGAT CAACCCAGAG 
ACGGGCGAGC AGATTCAGAG CTGGTATCGG AGCGGGGAGA CCTGGGATAG CAAGTTCAGC 
ACCATCGCCT CCAGCTACGA AGAGTGCCGG GCTGAGAGCG TGGGTCTCTA CCTCTGTCTC 
CACCCGCAAG TGCTGGAGAT CTTTGGCTTT GAGGGGGCTG ATGCGGAGGA CGTGATCTAC 
GTGAACTGGC TCAACATGGT TCGGGCCGGG CTGCTCGCTC TGGAGTTCTA CACACCTGAG 
GCCTTCAACT GGCGACAGGC CCATATGCAG GCCCGGTTTG TGATCCTGAG AGTCTTGCTG 
GAGGCTGGCG AGGGACTCGT TACCATCACT CCCACCACAG GCTCCGATGG GCGCCCAGAT 
GCCCGGGTCC GCCTCGACCG CAGCAAGATC CGGTCTGTGG GCAAGCCTGC TCTAGAGCGC 
TTCCTGCGGA GACTTCAGGT GCTGAAGTCC ACAGGGGATG TGGCCGGAGG GCGGGCCCTG 
TACGAGGGGT ATGCAACAGT CACTGATGCG CCCCCCGAGT GCTTCCTCAC CCTCAGGGAC 
ACGGTGCTGC TGCGTAAGGA ATCTCGGAAG CTCATTGTTC AGCCCAACAC TCGCCTTGAA 
GGCTCAGACG TGCAGCTTCT GGAATACGAG GCGTCAGCTG CTGGCCTCAT CCGATCCTTC 
TCTGAGCGTT TCCCAGAGGA TGGACCCGAG TTGGAGGAGA TCCTCACACA GCTGGCCACA 
GCCGATGCCC GATTCTGGAA GGGCCCCAGT GAGGCCCCAT CTGGCCAAGC TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_569710.2
CDS	41..2254
Translation	MADTQYILPNDIGVSSLDCREAFRLLSPTERLYAYHLSRAAWYGGLAVLLQTSPEAPYIYALLSRLFRAQDPDQLRQHALAEGLTEEEYQAFLVYAAGVYSNMGNYKSFGDTKFVPNLPKEKLERVILGSEAAQQHPEEVRGLWQTCGELMFSLEPRLRHLGLGKEGITTYFSGNCTMEDAKLAQDFLDSQNLSAYNTRLFKEVDGEGKPYYEVRLASVLGSEPSLDSEVTSKLKSYEFRGSPFQVTRGDYAPILQKVVEQLEKAKAYAANSHQGQMLAQYIESFTQGSIEAHKRGSRFWIQDKGPIVESYIGFIESYRDPFGSRGEFEGFVAVVNKAMSAKFERLVASAEQLLKELPWPPTFEKDKFLTPDFTSLDVLTFAGSGIPAGINIPNYDDLRQTEGFKNVSLGNVLAVAYATQREKLTFLEEDDKDLYILWKGPSFDVQVGLHELLGHGSGKLFVQDEKGAFNFDQETVINPETGEQIQSWYRSGETWDSKFSTIASSYEECRAESVGLYLCLHPQVLEIFGFEGADAEDVIYVNWLNMVRAGLLALEFYTPEAFNWRQAHMQARFVILRVLLEAGEGLVTITPTTGSDGRPDARVRLDRSKIRSVGKPALERFLRRLQVLKSTGDVAGGRALYEGYATVTDAPPECFLTLRDTVLLRKESRKLIVQPNTRLEGSDVQLLEYEASAAGLIRSFSERFPEDGPELEEILTQLATADARFWKGPSEAPSGQA

Target ORF information:

RefSeq Version	NM_130443.4
Organism	Homo sapiens(human)
Definition	Homo sapiens dipeptidyl peptidase 3 (DPP3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_130443.4

ORF Insert Sequence:

ATGGCGGACA CCCAGTACAT CCTGCCCAAT GACATCGGCG TGTCTAGCCT GGACTGCCGT 
GAGGCCTTCC GCCTGCTGTC ACCCACAGAG CGCCTCTATG CCTACCACCT GTCCCGTGCC 
GCCTGGTACG GAGGCCTGGC TGTGCTGCTT CAGACCTCCC CTGAGGCCCC CTACATCTAT 
GCTCTGCTCA GCCGCCTCTT CCGCGCCCAG GACCCCGACC AGCTGCGCCA ACATGCCCTG 
GCTGAAGGCC TTACCGAGGA GGAGTATCAG GCGTTCCTGG TCTATGCCGC GGGTGTTTAC 
TCCAACATGG GCAACTACAA GTCCTTTGGT GACACCAAGT TTGTTCCCAA CTTGCCCAAG 
GAAAAGCTGG AACGGGTGAT CCTAGGGAGT GAGGCTGCTC AGCAGCACCC AGAAGAAGTC 
AGGGGCCTCT GGCAGACCTG CGGGGAGCTT ATGTTCTCTC TGGAGCCAAG GCTTCGACAC 
CTCGGACTGG GGAAGGAGGG AATCACCACC TATTTCTCTG GGAATTGTAC CATGGAAGAT 
GCCAAATTGG CCCAGGACTT TCTGGACTCA CAGAACCTCA GTGCCTACAA CACCCGGCTC 
TTCAAAGAGG TCGATGGAGA AGGGAAGCCC TACTACGAGG TGCGGCTGGC TTCTGTGCTT 
GGCTCAGAGC CTTCCCTGGA CTCTGAGGTG ACTTCCAAGC TGAAGAGCTA TGAATTCCGG 
GGAAGCCCTT TCCAGGTGAC CCGGGGGGAC TACGCGCCCA TCCTCCAGAA GGTGGTGGAG 
CAGCTGGAGA AAGCCAAGGC CTATGCAGCC AACAGCCACC AGGGGCAGAT GCTGGCCCAG 
TATATAGAGA GCTTCACCCA GGGCTCCATC GAGGCCCACA AGAGGGGCTC CCGCTTCTGG 
ATCCAGGACA AAGGCCCCAT CGTGGAGAGT TACATCGGGT TCATCGAGAG CTACCGCGAC 
CCCTTTGGTT CCCGAGGAGA ATTTGAAGGT TTCGTAGCTG TGGTGAACAA GGCCATGAGT 
GCCAAGTTTG AGCGGCTGGT GGCGAGCGCA GAGCAGCTGC TGAAGGAGCT GCCCTGGCCC 
CCAACCTTTG AGAAGGACAA GTTCCTCACC CCTGACTTCA CCTCCCTGGA TGTTCTCACC 
TTCGCTGGCT CCGGCATCCC TGCCGGCATC AACATCCCCA ACTACGATGA TCTGAGGCAG 
ACGGAAGGCT TTAAGAACGT GTCGCTGGGG AATGTGCTGG CTGTGGCCTA CGCCACGCAG 
CGGGAGAAGC TTACCTTTCT GGAGGAGGAT GACAAGGACC TGTACATCCT CTGGAAGGGG 
CCCTCCTTCG ATGTGCAGGT GGGCCTGCAC GAGCTGCTGG GCCATGGCAG TGGCAAGCTC 
TTCGTACAGG ACGAAAAAGG AGCATTCAAC TTTGACCAGG AAACAGTGAT CAACCCAGAG 
ACGGGCGAGC AGATTCAGAG CTGGTATCGG AGCGGGGAGA CCTGGGATAG CAAGTTCAGC 
ACCATCGCCT CCAGCTACGA AGAGTGCCGG GCTGAGAGCG TGGGTCTCTA CCTCTGTCTC 
CACCCGCAAG TGCTGGAGAT CTTTGGCTTT GAGGGGGCTG ATGCGGAGGA CGTGATCTAC 
GTGAACTGGC TCAACATGGT TCGGGCCGGG CTGCTCGCTC TGGAGTTCTA CACACCTGAG 
GCCTTCAACT GGCGACAGGC CCATATGCAG GCCCGGTTTG TGATCCTGAG AGTCTTGCTG 
GAGGCTGGCG AGGGACTCGT TACCATCACT CCCACCACAG GCTCCGATGG GCGCCCAGAT 
GCCCGGGTCC GCCTCGACCG CAGCAAGATC CGGTCTGTGG GCAAGCCTGC TCTAGAGCGC 
TTCCTGCGGA GACTTCAGGT GCTGAAGTCC ACAGGGGATG TGGCCGGAGG GCGGGCCCTG 
TACGAGGGGT ATGCAACAGT CACTGATGCG CCCCCCGAGT GCTTCCTCAC CCTCAGGGAC 
ACGGTGCTGC TGCGTAAGGA ATCTCGGAAG CTCATTGTTC AGCCCAACAC TCGCCTTGAA 
GGCTCAGACG TGCAGCTTCT GGAATACGAG GCGTCAGCTG CTGGCCTCAT CCGATCCTTC 
TCTGAGCGTT TCCCAGAGGA TGGACCCGAG TTGGAGGAGA TCCTCACACA GCTGGCCACA 
GCCGATGCCC GATTCTGGAA GGGCCCCAGT GAGGCCCCAT CTGGCCAAGC TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DPP3 ( NM_130443.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_569710.2 Homo sapiens dipeptidyl peptidase 3 (DPP3), transcript variant 2, mRNA.

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CloneID	OHu26674
Clone ID Related Accession (Same CDS sequence)	NM_005700.4 , NM_130443.4 , NM_130443.3 , NM_005700.5
Accession Version	NM_130443.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2214bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	dipeptidyl peptidase 3 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC403406.1, DC325853.1, DC407885.1, BC024271.1, AL833475.1 and CD366941.1. This sequence is a reference standard in the RefSeqGene project. On Feb 15, 2012 this sequence version replaced NM_130443.2. Transcript Variant: This variant (2) uses an alternate acceptor splice site at a 5' non-coding exon compared to variant 1. Variants 1 and 2 encode the same isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.210600.1, SRR1803613.190878.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: lack of evidence for use of upstream AUG ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGACA CCCAGTACAT CCTGCCCAAT GACATCGGCG TGTCTAGCCT GGACTGCCGT 
GAGGCCTTCC GCCTGCTGTC ACCCACAGAG CGCCTCTATG CCTACCACCT GTCCCGTGCC 
GCCTGGTACG GAGGCCTGGC TGTGCTGCTT CAGACCTCCC CTGAGGCCCC CTACATCTAT 
GCTCTGCTCA GCCGCCTCTT CCGCGCCCAG GACCCCGACC AGCTGCGCCA ACATGCCCTG 
GCTGAAGGCC TTACCGAGGA GGAGTATCAG GCGTTCCTGG TCTATGCCGC GGGTGTTTAC 
TCCAACATGG GCAACTACAA GTCCTTTGGT GACACCAAGT TTGTTCCCAA CTTGCCCAAG 
GAAAAGCTGG AACGGGTGAT CCTAGGGAGT GAGGCTGCTC AGCAGCACCC AGAAGAAGTC 
AGGGGCCTCT GGCAGACCTG CGGGGAGCTT ATGTTCTCTC TGGAGCCAAG GCTTCGACAC 
CTCGGACTGG GGAAGGAGGG AATCACCACC TATTTCTCTG GGAATTGTAC CATGGAAGAT 
GCCAAATTGG CCCAGGACTT TCTGGACTCA CAGAACCTCA GTGCCTACAA CACCCGGCTC 
TTCAAAGAGG TCGATGGAGA AGGGAAGCCC TACTACGAGG TGCGGCTGGC TTCTGTGCTT 
GGCTCAGAGC CTTCCCTGGA CTCTGAGGTG ACTTCCAAGC TGAAGAGCTA TGAATTCCGG 
GGAAGCCCTT TCCAGGTGAC CCGGGGGGAC TACGCGCCCA TCCTCCAGAA GGTGGTGGAG 
CAGCTGGAGA AAGCCAAGGC CTATGCAGCC AACAGCCACC AGGGGCAGAT GCTGGCCCAG 
TATATAGAGA GCTTCACCCA GGGCTCCATC GAGGCCCACA AGAGGGGCTC CCGCTTCTGG 
ATCCAGGACA AAGGCCCCAT CGTGGAGAGT TACATCGGGT TCATCGAGAG CTACCGCGAC 
CCCTTTGGTT CCCGAGGAGA ATTTGAAGGT TTCGTAGCTG TGGTGAACAA GGCCATGAGT 
GCCAAGTTTG AGCGGCTGGT GGCGAGCGCA GAGCAGCTGC TGAAGGAGCT GCCCTGGCCC 
CCAACCTTTG AGAAGGACAA GTTCCTCACC CCTGACTTCA CCTCCCTGGA TGTTCTCACC 
TTCGCTGGCT CCGGCATCCC TGCCGGCATC AACATCCCCA ACTACGATGA TCTGAGGCAG 
ACGGAAGGCT TTAAGAACGT GTCGCTGGGG AATGTGCTGG CTGTGGCCTA CGCCACGCAG 
CGGGAGAAGC TTACCTTTCT GGAGGAGGAT GACAAGGACC TGTACATCCT CTGGAAGGGG 
CCCTCCTTCG ATGTGCAGGT GGGCCTGCAC GAGCTGCTGG GCCATGGCAG TGGCAAGCTC 
TTCGTACAGG ACGAAAAAGG AGCATTCAAC TTTGACCAGG AAACAGTGAT CAACCCAGAG 
ACGGGCGAGC AGATTCAGAG CTGGTATCGG AGCGGGGAGA CCTGGGATAG CAAGTTCAGC 
ACCATCGCCT CCAGCTACGA AGAGTGCCGG GCTGAGAGCG TGGGTCTCTA CCTCTGTCTC 
CACCCGCAAG TGCTGGAGAT CTTTGGCTTT GAGGGGGCTG ATGCGGAGGA CGTGATCTAC 
GTGAACTGGC TCAACATGGT TCGGGCCGGG CTGCTCGCTC TGGAGTTCTA CACACCTGAG 
GCCTTCAACT GGCGACAGGC CCATATGCAG GCCCGGTTTG TGATCCTGAG AGTCTTGCTG 
GAGGCTGGCG AGGGACTCGT TACCATCACT CCCACCACAG GCTCCGATGG GCGCCCAGAT 
GCCCGGGTCC GCCTCGACCG CAGCAAGATC CGGTCTGTGG GCAAGCCTGC TCTAGAGCGC 
TTCCTGCGGA GACTTCAGGT GCTGAAGTCC ACAGGGGATG TGGCCGGAGG GCGGGCCCTG 
TACGAGGGGT ATGCAACAGT CACTGATGCG CCCCCCGAGT GCTTCCTCAC CCTCAGGGAC 
ACGGTGCTGC TGCGTAAGGA ATCTCGGAAG CTCATTGTTC AGCCCAACAC TCGCCTTGAA 
GGCTCAGACG TGCAGCTTCT GGAATACGAG GCGTCAGCTG CTGGCCTCAT CCGATCCTTC 
TCTGAGCGTT TCCCAGAGGA TGGACCCGAG TTGGAGGAGA TCCTCACACA GCTGGCCACA 
GCCGATGCCC GATTCTGGAA GGGCCCCAGT GAGGCCCCAT CTGGCCAAGC TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_569710.2
CDS	462..2675
Translation	MADTQYILPNDIGVSSLDCREAFRLLSPTERLYAYHLSRAAWYGGLAVLLQTSPEAPYIYALLSRLFRAQDPDQLRQHALAEGLTEEEYQAFLVYAAGVYSNMGNYKSFGDTKFVPNLPKEKLERVILGSEAAQQHPEEVRGLWQTCGELMFSLEPRLRHLGLGKEGITTYFSGNCTMEDAKLAQDFLDSQNLSAYNTRLFKEVDGEGKPYYEVRLASVLGSEPSLDSEVTSKLKSYEFRGSPFQVTRGDYAPILQKVVEQLEKAKAYAANSHQGQMLAQYIESFTQGSIEAHKRGSRFWIQDKGPIVESYIGFIESYRDPFGSRGEFEGFVAVVNKAMSAKFERLVASAEQLLKELPWPPTFEKDKFLTPDFTSLDVLTFAGSGIPAGINIPNYDDLRQTEGFKNVSLGNVLAVAYATQREKLTFLEEDDKDLYILWKGPSFDVQVGLHELLGHGSGKLFVQDEKGAFNFDQETVINPETGEQIQSWYRSGETWDSKFSTIASSYEECRAESVGLYLCLHPQVLEIFGFEGADAEDVIYVNWLNMVRAGLLALEFYTPEAFNWRQAHMQARFVILRVLLEAGEGLVTITPTTGSDGRPDARVRLDRSKIRSVGKPALERFLRRLQVLKSTGDVAGGRALYEGYATVTDAPPECFLTLRDTVLLRKESRKLIVQPNTRLEGSDVQLLEYEASAAGLIRSFSERFPEDGPELEEILTQLATADARFWKGPSEAPSGQA

Target ORF information:

RefSeq Version	NM_130443.3
Organism	Homo sapiens(human)
Definition	Homo sapiens dipeptidyl peptidase 3 (DPP3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_130443.3

ORF Insert Sequence:

ATGGCGGACA CCCAGTACAT CCTGCCCAAT GACATCGGCG TGTCTAGCCT GGACTGCCGT 
GAGGCCTTCC GCCTGCTGTC ACCCACAGAG CGCCTCTATG CCTACCACCT GTCCCGTGCC 
GCCTGGTACG GAGGCCTGGC TGTGCTGCTT CAGACCTCCC CTGAGGCCCC CTACATCTAT 
GCTCTGCTCA GCCGCCTCTT CCGCGCCCAG GACCCCGACC AGCTGCGCCA ACATGCCCTG 
GCTGAAGGCC TTACCGAGGA GGAGTATCAG GCGTTCCTGG TCTATGCCGC GGGTGTTTAC 
TCCAACATGG GCAACTACAA GTCCTTTGGT GACACCAAGT TTGTTCCCAA CTTGCCCAAG 
GAAAAGCTGG AACGGGTGAT CCTAGGGAGT GAGGCTGCTC AGCAGCACCC AGAAGAAGTC 
AGGGGCCTCT GGCAGACCTG CGGGGAGCTT ATGTTCTCTC TGGAGCCAAG GCTTCGACAC 
CTCGGACTGG GGAAGGAGGG AATCACCACC TATTTCTCTG GGAATTGTAC CATGGAAGAT 
GCCAAATTGG CCCAGGACTT TCTGGACTCA CAGAACCTCA GTGCCTACAA CACCCGGCTC 
TTCAAAGAGG TCGATGGAGA AGGGAAGCCC TACTACGAGG TGCGGCTGGC TTCTGTGCTT 
GGCTCAGAGC CTTCCCTGGA CTCTGAGGTG ACTTCCAAGC TGAAGAGCTA TGAATTCCGG 
GGAAGCCCTT TCCAGGTGAC CCGGGGGGAC TACGCGCCCA TCCTCCAGAA GGTGGTGGAG 
CAGCTGGAGA AAGCCAAGGC CTATGCAGCC AACAGCCACC AGGGGCAGAT GCTGGCCCAG 
TATATAGAGA GCTTCACCCA GGGCTCCATC GAGGCCCACA AGAGGGGCTC CCGCTTCTGG 
ATCCAGGACA AAGGCCCCAT CGTGGAGAGT TACATCGGGT TCATCGAGAG CTACCGCGAC 
CCCTTTGGTT CCCGAGGAGA ATTTGAAGGT TTCGTAGCTG TGGTGAACAA GGCCATGAGT 
GCCAAGTTTG AGCGGCTGGT GGCGAGCGCA GAGCAGCTGC TGAAGGAGCT GCCCTGGCCC 
CCAACCTTTG AGAAGGACAA GTTCCTCACC CCTGACTTCA CCTCCCTGGA TGTTCTCACC 
TTCGCTGGCT CCGGCATCCC TGCCGGCATC AACATCCCCA ACTACGATGA TCTGAGGCAG 
ACGGAAGGCT TTAAGAACGT GTCGCTGGGG AATGTGCTGG CTGTGGCCTA CGCCACGCAG 
CGGGAGAAGC TTACCTTTCT GGAGGAGGAT GACAAGGACC TGTACATCCT CTGGAAGGGG 
CCCTCCTTCG ATGTGCAGGT GGGCCTGCAC GAGCTGCTGG GCCATGGCAG TGGCAAGCTC 
TTCGTACAGG ACGAAAAAGG AGCATTCAAC TTTGACCAGG AAACAGTGAT CAACCCAGAG 
ACGGGCGAGC AGATTCAGAG CTGGTATCGG AGCGGGGAGA CCTGGGATAG CAAGTTCAGC 
ACCATCGCCT CCAGCTACGA AGAGTGCCGG GCTGAGAGCG TGGGTCTCTA CCTCTGTCTC 
CACCCGCAAG TGCTGGAGAT CTTTGGCTTT GAGGGGGCTG ATGCGGAGGA CGTGATCTAC 
GTGAACTGGC TCAACATGGT TCGGGCCGGG CTGCTCGCTC TGGAGTTCTA CACACCTGAG 
GCCTTCAACT GGCGACAGGC CCATATGCAG GCCCGGTTTG TGATCCTGAG AGTCTTGCTG 
GAGGCTGGCG AGGGACTCGT TACCATCACT CCCACCACAG GCTCCGATGG GCGCCCAGAT 
GCCCGGGTCC GCCTCGACCG CAGCAAGATC CGGTCTGTGG GCAAGCCTGC TCTAGAGCGC 
TTCCTGCGGA GACTTCAGGT GCTGAAGTCC ACAGGGGATG TGGCCGGAGG GCGGGCCCTG 
TACGAGGGGT ATGCAACAGT CACTGATGCG CCCCCCGAGT GCTTCCTCAC CCTCAGGGAC 
ACGGTGCTGC TGCGTAAGGA ATCTCGGAAG CTCATTGTTC AGCCCAACAC TCGCCTTGAA 
GGCTCAGACG TGCAGCTTCT GGAATACGAG GCGTCAGCTG CTGGCCTCAT CCGATCCTTC 
TCTGAGCGTT TCCCAGAGGA TGGACCCGAG TTGGAGGAGA TCCTCACACA GCTGGCCACA 
GCCGATGCCC GATTCTGGAA GGGCCCCAGT GAGGCCCCAT CTGGCCAAGC TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DPP3 ( NM_005700.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_005691.2 Homo sapiens dipeptidyl peptidase 3 (DPP3), transcript variant 1, mRNA.

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CloneID	OHu26674
Clone ID Related Accession (Same CDS sequence)	NM_005700.4 , NM_130443.4 , NM_130443.3 , NM_005700.5
Accession Version	NM_005700.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2214bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Homo sapiens(human)
Product	dipeptidyl peptidase 3 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC407885.1, AK315478.1 and AJ271216.1. On Jun 3, 2019 this sequence version replaced NM_005700.4. Transcript Variant: This variant (1) encodes the longer isoform (1). Variants 1 and 2 encode the same isoform. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.176137.1, BC007221.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGACA CCCAGTACAT CCTGCCCAAT GACATCGGCG TGTCTAGCCT GGACTGCCGT 
GAGGCCTTCC GCCTGCTGTC ACCCACAGAG CGCCTCTATG CCTACCACCT GTCCCGTGCC 
GCCTGGTACG GAGGCCTGGC TGTGCTGCTT CAGACCTCCC CTGAGGCCCC CTACATCTAT 
GCTCTGCTCA GCCGCCTCTT CCGCGCCCAG GACCCCGACC AGCTGCGCCA ACATGCCCTG 
GCTGAAGGCC TTACCGAGGA GGAGTATCAG GCGTTCCTGG TCTATGCCGC GGGTGTTTAC 
TCCAACATGG GCAACTACAA GTCCTTTGGT GACACCAAGT TTGTTCCCAA CTTGCCCAAG 
GAAAAGCTGG AACGGGTGAT CCTAGGGAGT GAGGCTGCTC AGCAGCACCC AGAAGAAGTC 
AGGGGCCTCT GGCAGACCTG CGGGGAGCTT ATGTTCTCTC TGGAGCCAAG GCTTCGACAC 
CTCGGACTGG GGAAGGAGGG AATCACCACC TATTTCTCTG GGAATTGTAC CATGGAAGAT 
GCCAAATTGG CCCAGGACTT TCTGGACTCA CAGAACCTCA GTGCCTACAA CACCCGGCTC 
TTCAAAGAGG TCGATGGAGA AGGGAAGCCC TACTACGAGG TGCGGCTGGC TTCTGTGCTT 
GGCTCAGAGC CTTCCCTGGA CTCTGAGGTG ACTTCCAAGC TGAAGAGCTA TGAATTCCGG 
GGAAGCCCTT TCCAGGTGAC CCGGGGGGAC TACGCGCCCA TCCTCCAGAA GGTGGTGGAG 
CAGCTGGAGA AAGCCAAGGC CTATGCAGCC AACAGCCACC AGGGGCAGAT GCTGGCCCAG 
TATATAGAGA GCTTCACCCA GGGCTCCATC GAGGCCCACA AGAGGGGCTC CCGCTTCTGG 
ATCCAGGACA AAGGCCCCAT CGTGGAGAGT TACATCGGGT TCATCGAGAG CTACCGCGAC 
CCCTTTGGTT CCCGAGGAGA ATTTGAAGGT TTCGTAGCTG TGGTGAACAA GGCCATGAGT 
GCCAAGTTTG AGCGGCTGGT GGCGAGCGCA GAGCAGCTGC TGAAGGAGCT GCCCTGGCCC 
CCAACCTTTG AGAAGGACAA GTTCCTCACC CCTGACTTCA CCTCCCTGGA TGTTCTCACC 
TTCGCTGGCT CCGGCATCCC TGCCGGCATC AACATCCCCA ACTACGATGA TCTGAGGCAG 
ACGGAAGGCT TTAAGAACGT GTCGCTGGGG AATGTGCTGG CTGTGGCCTA CGCCACGCAG 
CGGGAGAAGC TTACCTTTCT GGAGGAGGAT GACAAGGACC TGTACATCCT CTGGAAGGGG 
CCCTCCTTCG ATGTGCAGGT GGGCCTGCAC GAGCTGCTGG GCCATGGCAG TGGCAAGCTC 
TTCGTACAGG ACGAAAAAGG AGCATTCAAC TTTGACCAGG AAACAGTGAT CAACCCAGAG 
ACGGGCGAGC AGATTCAGAG CTGGTATCGG AGCGGGGAGA CCTGGGATAG CAAGTTCAGC 
ACCATCGCCT CCAGCTACGA AGAGTGCCGG GCTGAGAGCG TGGGTCTCTA CCTCTGTCTC 
CACCCGCAAG TGCTGGAGAT CTTTGGCTTT GAGGGGGCTG ATGCGGAGGA CGTGATCTAC 
GTGAACTGGC TCAACATGGT TCGGGCCGGG CTGCTCGCTC TGGAGTTCTA CACACCTGAG 
GCCTTCAACT GGCGACAGGC CCATATGCAG GCCCGGTTTG TGATCCTGAG AGTCTTGCTG 
GAGGCTGGCG AGGGACTCGT TACCATCACT CCCACCACAG GCTCCGATGG GCGCCCAGAT 
GCCCGGGTCC GCCTCGACCG CAGCAAGATC CGGTCTGTGG GCAAGCCTGC TCTAGAGCGC 
TTCCTGCGGA GACTTCAGGT GCTGAAGTCC ACAGGGGATG TGGCCGGAGG GCGGGCCCTG 
TACGAGGGGT ATGCAACAGT CACTGATGCG CCCCCCGAGT GCTTCCTCAC CCTCAGGGAC 
ACGGTGCTGC TGCGTAAGGA ATCTCGGAAG CTCATTGTTC AGCCCAACAC TCGCCTTGAA 
GGCTCAGACG TGCAGCTTCT GGAATACGAG GCGTCAGCTG CTGGCCTCAT CCGATCCTTC 
TCTGAGCGTT TCCCAGAGGA TGGACCCGAG TTGGAGGAGA TCCTCACACA GCTGGCCACA 
GCCGATGCCC GATTCTGGAA GGGCCCCAGT GAGGCCCCAT CTGGCCAAGC TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005691.2
CDS	38..2251
Translation	MADTQYILPNDIGVSSLDCREAFRLLSPTERLYAYHLSRAAWYGGLAVLLQTSPEAPYIYALLSRLFRAQDPDQLRQHALAEGLTEEEYQAFLVYAAGVYSNMGNYKSFGDTKFVPNLPKEKLERVILGSEAAQQHPEEVRGLWQTCGELMFSLEPRLRHLGLGKEGITTYFSGNCTMEDAKLAQDFLDSQNLSAYNTRLFKEVDGEGKPYYEVRLASVLGSEPSLDSEVTSKLKSYEFRGSPFQVTRGDYAPILQKVVEQLEKAKAYAANSHQGQMLAQYIESFTQGSIEAHKRGSRFWIQDKGPIVESYIGFIESYRDPFGSRGEFEGFVAVVNKAMSAKFERLVASAEQLLKELPWPPTFEKDKFLTPDFTSLDVLTFAGSGIPAGINIPNYDDLRQTEGFKNVSLGNVLAVAYATQREKLTFLEEDDKDLYILWKGPSFDVQVGLHELLGHGSGKLFVQDEKGAFNFDQETVINPETGEQIQSWYRSGETWDSKFSTIASSYEECRAESVGLYLCLHPQVLEIFGFEGADAEDVIYVNWLNMVRAGLLALEFYTPEAFNWRQAHMQARFVILRVLLEAGEGLVTITPTTGSDGRPDARVRLDRSKIRSVGKPALERFLRRLQVLKSTGDVAGGRALYEGYATVTDAPPECFLTLRDTVLLRKESRKLIVQPNTRLEGSDVQLLEYEASAAGLIRSFSERFPEDGPELEEILTQLATADARFWKGPSEAPSGQA

Target ORF information:

RefSeq Version	NM_005700.5
Organism	Homo sapiens(human)
Definition	Homo sapiens dipeptidyl peptidase 3 (DPP3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005700.5

ORF Insert Sequence:

ATGGCGGACA CCCAGTACAT CCTGCCCAAT GACATCGGCG TGTCTAGCCT GGACTGCCGT 
GAGGCCTTCC GCCTGCTGTC ACCCACAGAG CGCCTCTATG CCTACCACCT GTCCCGTGCC 
GCCTGGTACG GAGGCCTGGC TGTGCTGCTT CAGACCTCCC CTGAGGCCCC CTACATCTAT 
GCTCTGCTCA GCCGCCTCTT CCGCGCCCAG GACCCCGACC AGCTGCGCCA ACATGCCCTG 
GCTGAAGGCC TTACCGAGGA GGAGTATCAG GCGTTCCTGG TCTATGCCGC GGGTGTTTAC 
TCCAACATGG GCAACTACAA GTCCTTTGGT GACACCAAGT TTGTTCCCAA CTTGCCCAAG 
GAAAAGCTGG AACGGGTGAT CCTAGGGAGT GAGGCTGCTC AGCAGCACCC AGAAGAAGTC 
AGGGGCCTCT GGCAGACCTG CGGGGAGCTT ATGTTCTCTC TGGAGCCAAG GCTTCGACAC 
CTCGGACTGG GGAAGGAGGG AATCACCACC TATTTCTCTG GGAATTGTAC CATGGAAGAT 
GCCAAATTGG CCCAGGACTT TCTGGACTCA CAGAACCTCA GTGCCTACAA CACCCGGCTC 
TTCAAAGAGG TCGATGGAGA AGGGAAGCCC TACTACGAGG TGCGGCTGGC TTCTGTGCTT 
GGCTCAGAGC CTTCCCTGGA CTCTGAGGTG ACTTCCAAGC TGAAGAGCTA TGAATTCCGG 
GGAAGCCCTT TCCAGGTGAC CCGGGGGGAC TACGCGCCCA TCCTCCAGAA GGTGGTGGAG 
CAGCTGGAGA AAGCCAAGGC CTATGCAGCC AACAGCCACC AGGGGCAGAT GCTGGCCCAG 
TATATAGAGA GCTTCACCCA GGGCTCCATC GAGGCCCACA AGAGGGGCTC CCGCTTCTGG 
ATCCAGGACA AAGGCCCCAT CGTGGAGAGT TACATCGGGT TCATCGAGAG CTACCGCGAC 
CCCTTTGGTT CCCGAGGAGA ATTTGAAGGT TTCGTAGCTG TGGTGAACAA GGCCATGAGT 
GCCAAGTTTG AGCGGCTGGT GGCGAGCGCA GAGCAGCTGC TGAAGGAGCT GCCCTGGCCC 
CCAACCTTTG AGAAGGACAA GTTCCTCACC CCTGACTTCA CCTCCCTGGA TGTTCTCACC 
TTCGCTGGCT CCGGCATCCC TGCCGGCATC AACATCCCCA ACTACGATGA TCTGAGGCAG 
ACGGAAGGCT TTAAGAACGT GTCGCTGGGG AATGTGCTGG CTGTGGCCTA CGCCACGCAG 
CGGGAGAAGC TTACCTTTCT GGAGGAGGAT GACAAGGACC TGTACATCCT CTGGAAGGGG 
CCCTCCTTCG ATGTGCAGGT GGGCCTGCAC GAGCTGCTGG GCCATGGCAG TGGCAAGCTC 
TTCGTACAGG ACGAAAAAGG AGCATTCAAC TTTGACCAGG AAACAGTGAT CAACCCAGAG 
ACGGGCGAGC AGATTCAGAG CTGGTATCGG AGCGGGGAGA CCTGGGATAG CAAGTTCAGC 
ACCATCGCCT CCAGCTACGA AGAGTGCCGG GCTGAGAGCG TGGGTCTCTA CCTCTGTCTC 
CACCCGCAAG TGCTGGAGAT CTTTGGCTTT GAGGGGGCTG ATGCGGAGGA CGTGATCTAC 
GTGAACTGGC TCAACATGGT TCGGGCCGGG CTGCTCGCTC TGGAGTTCTA CACACCTGAG 
GCCTTCAACT GGCGACAGGC CCATATGCAG GCCCGGTTTG TGATCCTGAG AGTCTTGCTG 
GAGGCTGGCG AGGGACTCGT TACCATCACT CCCACCACAG GCTCCGATGG GCGCCCAGAT 
GCCCGGGTCC GCCTCGACCG CAGCAAGATC CGGTCTGTGG GCAAGCCTGC TCTAGAGCGC 
TTCCTGCGGA GACTTCAGGT GCTGAAGTCC ACAGGGGATG TGGCCGGAGG GCGGGCCCTG 
TACGAGGGGT ATGCAACAGT CACTGATGCG CCCCCCGAGT GCTTCCTCAC CCTCAGGGAC 
ACGGTGCTGC TGCGTAAGGA ATCTCGGAAG CTCATTGTTC AGCCCAACAC TCGCCTTGAA 
GGCTCAGACG TGCAGCTTCT GGAATACGAG GCGTCAGCTG CTGGCCTCAT CCGATCCTTC 
TCTGAGCGTT TCCCAGAGGA TGGACCCGAG TTGGAGGAGA TCCTCACACA GCTGGCCACA 
GCCGATGCCC GATTCTGGAA GGGCCCCAGT GAGGCCCCAT CTGGCCAAGC TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DPP3 ( NM_001256670.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001243599.1 Homo sapiens dipeptidyl peptidase 3 (DPP3), transcript variant 3, mRNA.

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CloneID	OHu26862
Clone ID Related Accession (Same CDS sequence)	NM_001256670.1 , NM_001256670.2
Accession Version	NM_001256670.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2124bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	dipeptidyl peptidase 3 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC403406.1, DC325853.1, DC407885.1, AK297199.1, AK315478.1, AJ271216.1 and CD366941.1. Transcript Variant: This variant (3) lacks an in-frame coding exon compared to variant 1. This results in a shorter isoform (2) missing an internal protein segment compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK297199.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA2149004 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: lack of evidence for use of upstream AUG ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGACA CCCAGTACAT CCTGCCCAAT GACATCGGCG TGTCTAGCCT GGACTGCCGT 
GAGGCCTTCC GCCTGCTGTC ACCCACAGAG CGCCTCTATG CCTACCACCT GTCCCGTGCC 
GCCTGGTACG GAGGCCTGGC TGTGCTGCTT CAGACCTCCC CTGAGGCCCC CTACATCTAT 
GCTCTGCTCA GCCGCCTCTT CCGCGCCCAG GACCCCGACC AGCTGCGCCA ACATGCCCTG 
GCTGAAGGCC TTACCGAGGA GGAGTATCAG GAAAAGCTGG AACGGGTGAT CCTAGGGAGT 
GAGGCTGCTC AGCAGCACCC AGAAGAAGTC AGGGGCCTCT GGCAGACCTG CGGGGAGCTT 
ATGTTCTCTC TGGAGCCAAG GCTTCGACAC CTCGGACTGG GGAAGGAGGG AATCACCACC 
TATTTCTCTG GGAATTGTAC CATGGAAGAT GCCAAATTGG CCCAGGACTT TCTGGACTCA 
CAGAACCTCA GTGCCTACAA CACCCGGCTC TTCAAAGAGG TCGATGGAGA AGGGAAGCCC 
TACTACGAGG TGCGGCTGGC TTCTGTGCTT GGCTCAGAGC CTTCCCTGGA CTCTGAGGTG 
ACTTCCAAGC TGAAGAGCTA TGAATTCCGG GGAAGCCCTT TCCAGGTGAC CCGGGGGGAC 
TACGCGCCCA TCCTCCAGAA GGTGGTGGAG CAGCTGGAGA AAGCCAAGGC CTATGCAGCC 
AACAGCCACC AGGGGCAGAT GCTGGCCCAG TATATAGAGA GCTTCACCCA GGGCTCCATC 
GAGGCCCACA AGAGGGGCTC CCGCTTCTGG ATCCAGGACA AAGGCCCCAT CGTGGAGAGT 
TACATCGGGT TCATCGAGAG CTACCGCGAC CCCTTTGGTT CCCGAGGAGA ATTTGAAGGT 
TTCGTAGCTG TGGTGAACAA GGCCATGAGT GCCAAGTTTG AGCGGCTGGT GGCGAGCGCA 
GAGCAGCTGC TGAAGGAGCT GCCCTGGCCC CCAACCTTTG AGAAGGACAA GTTCCTCACC 
CCTGACTTCA CCTCCCTGGA TGTTCTCACC TTCGCTGGCT CCGGCATCCC TGCCGGCATC 
AACATCCCCA ACTACGATGA TCTGAGGCAG ACGGAAGGCT TTAAGAACGT GTCGCTGGGG 
AATGTGCTGG CTGTGGCCTA CGCCACGCAG CGGGAGAAGC TTACCTTTCT GGAGGAGGAT 
GACAAGGACC TGTACATCCT CTGGAAGGGG CCCTCCTTCG ATGTGCAGGT GGGCCTGCAC 
GAGCTGCTGG GCCATGGCAG TGGCAAGCTC TTCGTACAGG ACGAAAAAGG AGCATTCAAC 
TTTGACCAGG AAACAGTGAT CAACCCAGAG ACGGGCGAGC AGATTCAGAG CTGGTATCGG 
AGCGGGGAGA CCTGGGATAG CAAGTTCAGC ACCATCGCCT CCAGCTACGA AGAGTGCCGG 
GCTGAGAGCG TGGGTCTCTA CCTCTGTCTC CACCCGCAAG TGCTGGAGAT CTTTGGCTTT 
GAGGGGGCTG ATGCGGAGGA CGTGATCTAC GTGAACTGGC TCAACATGGT TCGGGCCGGG 
CTGCTCGCTC TGGAGTTCTA CACACCTGAG GCCTTCAACT GGCGACAGGC CCATATGCAG 
GCCCGGTTTG TGATCCTGAG AGTCTTGCTG GAGGCTGGCG AGGGACTCGT TACCATCACT 
CCCACCACAG GCTCCGATGG GCGCCCAGAT GCCCGGGTCC GCCTCGACCG CAGCAAGATC 
CGGTCTGTGG GCAAGCCTGC TCTAGAGCGC TTCCTGCGGA GACTTCAGGT GCTGAAGTCC 
ACAGGGGATG TGGCCGGAGG GCGGGCCCTG TACGAGGGGT ATGCAACAGT CACTGATGCG 
CCCCCCGAGT GCTTCCTCAC CCTCAGGGAC ACGGTGCTGC TGCGTAAGGA ATCTCGGAAG 
CTCATTGTTC AGCCCAACAC TCGCCTTGAA GGCTCAGACG TGCAGCTTCT GGAATACGAG 
GCGTCAGCTG CTGGCCTCAT CCGATCCTTC TCTGAGCGTT TCCCAGAGGA TGGACCCGAG 
TTGGAGGAGA TCCTCACACA GCTGGCCACA GCCGATGCCC GATTCTGGAA GGGCCCCAGT 
GAGGCCCCAT CTGGCCAAGC TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001243599.1
CDS	459..2582
Translation	MADTQYILPNDIGVSSLDCREAFRLLSPTERLYAYHLSRAAWYGGLAVLLQTSPEAPYIYALLSRLFRAQDPDQLRQHALAEGLTEEEYQEKLERVILGSEAAQQHPEEVRGLWQTCGELMFSLEPRLRHLGLGKEGITTYFSGNCTMEDAKLAQDFLDSQNLSAYNTRLFKEVDGEGKPYYEVRLASVLGSEPSLDSEVTSKLKSYEFRGSPFQVTRGDYAPILQKVVEQLEKAKAYAANSHQGQMLAQYIESFTQGSIEAHKRGSRFWIQDKGPIVESYIGFIESYRDPFGSRGEFEGFVAVVNKAMSAKFERLVASAEQLLKELPWPPTFEKDKFLTPDFTSLDVLTFAGSGIPAGINIPNYDDLRQTEGFKNVSLGNVLAVAYATQREKLTFLEEDDKDLYILWKGPSFDVQVGLHELLGHGSGKLFVQDEKGAFNFDQETVINPETGEQIQSWYRSGETWDSKFSTIASSYEECRAESVGLYLCLHPQVLEIFGFEGADAEDVIYVNWLNMVRAGLLALEFYTPEAFNWRQAHMQARFVILRVLLEAGEGLVTITPTTGSDGRPDARVRLDRSKIRSVGKPALERFLRRLQVLKSTGDVAGGRALYEGYATVTDAPPECFLTLRDTVLLRKESRKLIVQPNTRLEGSDVQLLEYEASAAGLIRSFSERFPEDGPELEEILTQLATADARFWKGPSEAPSGQA

Target ORF information:

RefSeq Version	NM_001256670.1
Organism	Homo sapiens(human)
Definition	Homo sapiens dipeptidyl peptidase 3 (DPP3), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001256670.1

ORF Insert Sequence:

ATGGCGGACA CCCAGTACAT CCTGCCCAAT GACATCGGCG TGTCTAGCCT GGACTGCCGT 
GAGGCCTTCC GCCTGCTGTC ACCCACAGAG CGCCTCTATG CCTACCACCT GTCCCGTGCC 
GCCTGGTACG GAGGCCTGGC TGTGCTGCTT CAGACCTCCC CTGAGGCCCC CTACATCTAT 
GCTCTGCTCA GCCGCCTCTT CCGCGCCCAG GACCCCGACC AGCTGCGCCA ACATGCCCTG 
GCTGAAGGCC TTACCGAGGA GGAGTATCAG GAAAAGCTGG AACGGGTGAT CCTAGGGAGT 
GAGGCTGCTC AGCAGCACCC AGAAGAAGTC AGGGGCCTCT GGCAGACCTG CGGGGAGCTT 
ATGTTCTCTC TGGAGCCAAG GCTTCGACAC CTCGGACTGG GGAAGGAGGG AATCACCACC 
TATTTCTCTG GGAATTGTAC CATGGAAGAT GCCAAATTGG CCCAGGACTT TCTGGACTCA 
CAGAACCTCA GTGCCTACAA CACCCGGCTC TTCAAAGAGG TCGATGGAGA AGGGAAGCCC 
TACTACGAGG TGCGGCTGGC TTCTGTGCTT GGCTCAGAGC CTTCCCTGGA CTCTGAGGTG 
ACTTCCAAGC TGAAGAGCTA TGAATTCCGG GGAAGCCCTT TCCAGGTGAC CCGGGGGGAC 
TACGCGCCCA TCCTCCAGAA GGTGGTGGAG CAGCTGGAGA AAGCCAAGGC CTATGCAGCC 
AACAGCCACC AGGGGCAGAT GCTGGCCCAG TATATAGAGA GCTTCACCCA GGGCTCCATC 
GAGGCCCACA AGAGGGGCTC CCGCTTCTGG ATCCAGGACA AAGGCCCCAT CGTGGAGAGT 
TACATCGGGT TCATCGAGAG CTACCGCGAC CCCTTTGGTT CCCGAGGAGA ATTTGAAGGT 
TTCGTAGCTG TGGTGAACAA GGCCATGAGT GCCAAGTTTG AGCGGCTGGT GGCGAGCGCA 
GAGCAGCTGC TGAAGGAGCT GCCCTGGCCC CCAACCTTTG AGAAGGACAA GTTCCTCACC 
CCTGACTTCA CCTCCCTGGA TGTTCTCACC TTCGCTGGCT CCGGCATCCC TGCCGGCATC 
AACATCCCCA ACTACGATGA TCTGAGGCAG ACGGAAGGCT TTAAGAACGT GTCGCTGGGG 
AATGTGCTGG CTGTGGCCTA CGCCACGCAG CGGGAGAAGC TTACCTTTCT GGAGGAGGAT 
GACAAGGACC TGTACATCCT CTGGAAGGGG CCCTCCTTCG ATGTGCAGGT GGGCCTGCAC 
GAGCTGCTGG GCCATGGCAG TGGCAAGCTC TTCGTACAGG ACGAAAAAGG AGCATTCAAC 
TTTGACCAGG AAACAGTGAT CAACCCAGAG ACGGGCGAGC AGATTCAGAG CTGGTATCGG 
AGCGGGGAGA CCTGGGATAG CAAGTTCAGC ACCATCGCCT CCAGCTACGA AGAGTGCCGG 
GCTGAGAGCG TGGGTCTCTA CCTCTGTCTC CACCCGCAAG TGCTGGAGAT CTTTGGCTTT 
GAGGGGGCTG ATGCGGAGGA CGTGATCTAC GTGAACTGGC TCAACATGGT TCGGGCCGGG 
CTGCTCGCTC TGGAGTTCTA CACACCTGAG GCCTTCAACT GGCGACAGGC CCATATGCAG 
GCCCGGTTTG TGATCCTGAG AGTCTTGCTG GAGGCTGGCG AGGGACTCGT TACCATCACT 
CCCACCACAG GCTCCGATGG GCGCCCAGAT GCCCGGGTCC GCCTCGACCG CAGCAAGATC 
CGGTCTGTGG GCAAGCCTGC TCTAGAGCGC TTCCTGCGGA GACTTCAGGT GCTGAAGTCC 
ACAGGGGATG TGGCCGGAGG GCGGGCCCTG TACGAGGGGT ATGCAACAGT CACTGATGCG 
CCCCCCGAGT GCTTCCTCAC CCTCAGGGAC ACGGTGCTGC TGCGTAAGGA ATCTCGGAAG 
CTCATTGTTC AGCCCAACAC TCGCCTTGAA GGCTCAGACG TGCAGCTTCT GGAATACGAG 
GCGTCAGCTG CTGGCCTCAT CCGATCCTTC TCTGAGCGTT TCCCAGAGGA TGGACCCGAG 
TTGGAGGAGA TCCTCACACA GCTGGCCACA GCCGATGCCC GATTCTGGAA GGGCCCCAGT 
GAGGCCCCAT CTGGCCAAGC TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DPP3 ( NM_001256670.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001243599.1 Homo sapiens dipeptidyl peptidase 3 (DPP3), transcript variant 3, mRNA.

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CloneID	OHu26862
Clone ID Related Accession (Same CDS sequence)	NM_001256670.1 , NM_001256670.2
Accession Version	NM_001256670.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2124bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-19
Organism	Homo sapiens(human)
Product	dipeptidyl peptidase 3 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC407885.1, AK297199.1, AK315478.1 and AJ271216.1. On Jun 3, 2019 this sequence version replaced NM_001256670.1. Transcript Variant: This variant (3) lacks an in-frame coding exon compared to variant 1. This results in a shorter isoform (2) missing an internal protein segment compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK297199.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA2149004 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGACA CCCAGTACAT CCTGCCCAAT GACATCGGCG TGTCTAGCCT GGACTGCCGT 
GAGGCCTTCC GCCTGCTGTC ACCCACAGAG CGCCTCTATG CCTACCACCT GTCCCGTGCC 
GCCTGGTACG GAGGCCTGGC TGTGCTGCTT CAGACCTCCC CTGAGGCCCC CTACATCTAT 
GCTCTGCTCA GCCGCCTCTT CCGCGCCCAG GACCCCGACC AGCTGCGCCA ACATGCCCTG 
GCTGAAGGCC TTACCGAGGA GGAGTATCAG GAAAAGCTGG AACGGGTGAT CCTAGGGAGT 
GAGGCTGCTC AGCAGCACCC AGAAGAAGTC AGGGGCCTCT GGCAGACCTG CGGGGAGCTT 
ATGTTCTCTC TGGAGCCAAG GCTTCGACAC CTCGGACTGG GGAAGGAGGG AATCACCACC 
TATTTCTCTG GGAATTGTAC CATGGAAGAT GCCAAATTGG CCCAGGACTT TCTGGACTCA 
CAGAACCTCA GTGCCTACAA CACCCGGCTC TTCAAAGAGG TCGATGGAGA AGGGAAGCCC 
TACTACGAGG TGCGGCTGGC TTCTGTGCTT GGCTCAGAGC CTTCCCTGGA CTCTGAGGTG 
ACTTCCAAGC TGAAGAGCTA TGAATTCCGG GGAAGCCCTT TCCAGGTGAC CCGGGGGGAC 
TACGCGCCCA TCCTCCAGAA GGTGGTGGAG CAGCTGGAGA AAGCCAAGGC CTATGCAGCC 
AACAGCCACC AGGGGCAGAT GCTGGCCCAG TATATAGAGA GCTTCACCCA GGGCTCCATC 
GAGGCCCACA AGAGGGGCTC CCGCTTCTGG ATCCAGGACA AAGGCCCCAT CGTGGAGAGT 
TACATCGGGT TCATCGAGAG CTACCGCGAC CCCTTTGGTT CCCGAGGAGA ATTTGAAGGT 
TTCGTAGCTG TGGTGAACAA GGCCATGAGT GCCAAGTTTG AGCGGCTGGT GGCGAGCGCA 
GAGCAGCTGC TGAAGGAGCT GCCCTGGCCC CCAACCTTTG AGAAGGACAA GTTCCTCACC 
CCTGACTTCA CCTCCCTGGA TGTTCTCACC TTCGCTGGCT CCGGCATCCC TGCCGGCATC 
AACATCCCCA ACTACGATGA TCTGAGGCAG ACGGAAGGCT TTAAGAACGT GTCGCTGGGG 
AATGTGCTGG CTGTGGCCTA CGCCACGCAG CGGGAGAAGC TTACCTTTCT GGAGGAGGAT 
GACAAGGACC TGTACATCCT CTGGAAGGGG CCCTCCTTCG ATGTGCAGGT GGGCCTGCAC 
GAGCTGCTGG GCCATGGCAG TGGCAAGCTC TTCGTACAGG ACGAAAAAGG AGCATTCAAC 
TTTGACCAGG AAACAGTGAT CAACCCAGAG ACGGGCGAGC AGATTCAGAG CTGGTATCGG 
AGCGGGGAGA CCTGGGATAG CAAGTTCAGC ACCATCGCCT CCAGCTACGA AGAGTGCCGG 
GCTGAGAGCG TGGGTCTCTA CCTCTGTCTC CACCCGCAAG TGCTGGAGAT CTTTGGCTTT 
GAGGGGGCTG ATGCGGAGGA CGTGATCTAC GTGAACTGGC TCAACATGGT TCGGGCCGGG 
CTGCTCGCTC TGGAGTTCTA CACACCTGAG GCCTTCAACT GGCGACAGGC CCATATGCAG 
GCCCGGTTTG TGATCCTGAG AGTCTTGCTG GAGGCTGGCG AGGGACTCGT TACCATCACT 
CCCACCACAG GCTCCGATGG GCGCCCAGAT GCCCGGGTCC GCCTCGACCG CAGCAAGATC 
CGGTCTGTGG GCAAGCCTGC TCTAGAGCGC TTCCTGCGGA GACTTCAGGT GCTGAAGTCC 
ACAGGGGATG TGGCCGGAGG GCGGGCCCTG TACGAGGGGT ATGCAACAGT CACTGATGCG 
CCCCCCGAGT GCTTCCTCAC CCTCAGGGAC ACGGTGCTGC TGCGTAAGGA ATCTCGGAAG 
CTCATTGTTC AGCCCAACAC TCGCCTTGAA GGCTCAGACG TGCAGCTTCT GGAATACGAG 
GCGTCAGCTG CTGGCCTCAT CCGATCCTTC TCTGAGCGTT TCCCAGAGGA TGGACCCGAG 
TTGGAGGAGA TCCTCACACA GCTGGCCACA GCCGATGCCC GATTCTGGAA GGGCCCCAGT 
GAGGCCCCAT CTGGCCAAGC TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001243599.1
CDS	38..2161
Translation	MADTQYILPNDIGVSSLDCREAFRLLSPTERLYAYHLSRAAWYGGLAVLLQTSPEAPYIYALLSRLFRAQDPDQLRQHALAEGLTEEEYQEKLERVILGSEAAQQHPEEVRGLWQTCGELMFSLEPRLRHLGLGKEGITTYFSGNCTMEDAKLAQDFLDSQNLSAYNTRLFKEVDGEGKPYYEVRLASVLGSEPSLDSEVTSKLKSYEFRGSPFQVTRGDYAPILQKVVEQLEKAKAYAANSHQGQMLAQYIESFTQGSIEAHKRGSRFWIQDKGPIVESYIGFIESYRDPFGSRGEFEGFVAVVNKAMSAKFERLVASAEQLLKELPWPPTFEKDKFLTPDFTSLDVLTFAGSGIPAGINIPNYDDLRQTEGFKNVSLGNVLAVAYATQREKLTFLEEDDKDLYILWKGPSFDVQVGLHELLGHGSGKLFVQDEKGAFNFDQETVINPETGEQIQSWYRSGETWDSKFSTIASSYEECRAESVGLYLCLHPQVLEIFGFEGADAEDVIYVNWLNMVRAGLLALEFYTPEAFNWRQAHMQARFVILRVLLEAGEGLVTITPTTGSDGRPDARVRLDRSKIRSVGKPALERFLRRLQVLKSTGDVAGGRALYEGYATVTDAPPECFLTLRDTVLLRKESRKLIVQPNTRLEGSDVQLLEYEASAAGLIRSFSERFPEDGPELEEILTQLATADARFWKGPSEAPSGQA

Target ORF information:

RefSeq Version	NM_001256670.2
Organism	Homo sapiens(human)
Definition	Homo sapiens dipeptidyl peptidase 3 (DPP3), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001256670.2

ORF Insert Sequence:

ATGGCGGACA CCCAGTACAT CCTGCCCAAT GACATCGGCG TGTCTAGCCT GGACTGCCGT 
GAGGCCTTCC GCCTGCTGTC ACCCACAGAG CGCCTCTATG CCTACCACCT GTCCCGTGCC 
GCCTGGTACG GAGGCCTGGC TGTGCTGCTT CAGACCTCCC CTGAGGCCCC CTACATCTAT 
GCTCTGCTCA GCCGCCTCTT CCGCGCCCAG GACCCCGACC AGCTGCGCCA ACATGCCCTG 
GCTGAAGGCC TTACCGAGGA GGAGTATCAG GAAAAGCTGG AACGGGTGAT CCTAGGGAGT 
GAGGCTGCTC AGCAGCACCC AGAAGAAGTC AGGGGCCTCT GGCAGACCTG CGGGGAGCTT 
ATGTTCTCTC TGGAGCCAAG GCTTCGACAC CTCGGACTGG GGAAGGAGGG AATCACCACC 
TATTTCTCTG GGAATTGTAC CATGGAAGAT GCCAAATTGG CCCAGGACTT TCTGGACTCA 
CAGAACCTCA GTGCCTACAA CACCCGGCTC TTCAAAGAGG TCGATGGAGA AGGGAAGCCC 
TACTACGAGG TGCGGCTGGC TTCTGTGCTT GGCTCAGAGC CTTCCCTGGA CTCTGAGGTG 
ACTTCCAAGC TGAAGAGCTA TGAATTCCGG GGAAGCCCTT TCCAGGTGAC CCGGGGGGAC 
TACGCGCCCA TCCTCCAGAA GGTGGTGGAG CAGCTGGAGA AAGCCAAGGC CTATGCAGCC 
AACAGCCACC AGGGGCAGAT GCTGGCCCAG TATATAGAGA GCTTCACCCA GGGCTCCATC 
GAGGCCCACA AGAGGGGCTC CCGCTTCTGG ATCCAGGACA AAGGCCCCAT CGTGGAGAGT 
TACATCGGGT TCATCGAGAG CTACCGCGAC CCCTTTGGTT CCCGAGGAGA ATTTGAAGGT 
TTCGTAGCTG TGGTGAACAA GGCCATGAGT GCCAAGTTTG AGCGGCTGGT GGCGAGCGCA 
GAGCAGCTGC TGAAGGAGCT GCCCTGGCCC CCAACCTTTG AGAAGGACAA GTTCCTCACC 
CCTGACTTCA CCTCCCTGGA TGTTCTCACC TTCGCTGGCT CCGGCATCCC TGCCGGCATC 
AACATCCCCA ACTACGATGA TCTGAGGCAG ACGGAAGGCT TTAAGAACGT GTCGCTGGGG 
AATGTGCTGG CTGTGGCCTA CGCCACGCAG CGGGAGAAGC TTACCTTTCT GGAGGAGGAT 
GACAAGGACC TGTACATCCT CTGGAAGGGG CCCTCCTTCG ATGTGCAGGT GGGCCTGCAC 
GAGCTGCTGG GCCATGGCAG TGGCAAGCTC TTCGTACAGG ACGAAAAAGG AGCATTCAAC 
TTTGACCAGG AAACAGTGAT CAACCCAGAG ACGGGCGAGC AGATTCAGAG CTGGTATCGG 
AGCGGGGAGA CCTGGGATAG CAAGTTCAGC ACCATCGCCT CCAGCTACGA AGAGTGCCGG 
GCTGAGAGCG TGGGTCTCTA CCTCTGTCTC CACCCGCAAG TGCTGGAGAT CTTTGGCTTT 
GAGGGGGCTG ATGCGGAGGA CGTGATCTAC GTGAACTGGC TCAACATGGT TCGGGCCGGG 
CTGCTCGCTC TGGAGTTCTA CACACCTGAG GCCTTCAACT GGCGACAGGC CCATATGCAG 
GCCCGGTTTG TGATCCTGAG AGTCTTGCTG GAGGCTGGCG AGGGACTCGT TACCATCACT 
CCCACCACAG GCTCCGATGG GCGCCCAGAT GCCCGGGTCC GCCTCGACCG CAGCAAGATC 
CGGTCTGTGG GCAAGCCTGC TCTAGAGCGC TTCCTGCGGA GACTTCAGGT GCTGAAGTCC 
ACAGGGGATG TGGCCGGAGG GCGGGCCCTG TACGAGGGGT ATGCAACAGT CACTGATGCG 
CCCCCCGAGT GCTTCCTCAC CCTCAGGGAC ACGGTGCTGC TGCGTAAGGA ATCTCGGAAG 
CTCATTGTTC AGCCCAACAC TCGCCTTGAA GGCTCAGACG TGCAGCTTCT GGAATACGAG 
GCGTCAGCTG CTGGCCTCAT CCGATCCTTC TCTGAGCGTT TCCCAGAGGA TGGACCCGAG 
TTGGAGGAGA TCCTCACACA GCTGGCCACA GCCGATGCCC GATTCTGGAA GGGCCCCAGT 
GAGGCCCCAT CTGGCCAAGC TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Identification of dipeptidyl peptidase 3 as the Angiotensin-(1-7) degrading peptidase in human HK-2 renal epithelial cells.
Peptides8329-37(2016 Sep)
Cruz-Diaz N,Wilson BA,Pirro NT,Brosnihan KB,Marshall AC,Chappell MC

Human dipeptidyl peptidase III regulates G-protein coupled receptor-dependent Ca2+ concentration in human embryonic kidney 293T cells.
Biological chemistry397(6)563-9(2016 Jun)
Prajapati SC,Singh R,Chauhan SS

Human dipeptidyl peptidase III mRNA variant I and II are expressed concurrently in multiple tumor derived cell lines and translated at comparable efficiency in vitro.
Molecular biology reports43(6)457-62(2016 Jun)
Prajapati SC,Chauhan SS

Substrate complexes of human dipeptidyl peptidase III reveal the mechanism of enzyme inhibition.
Scientific reports623787(2016 Mar)
Kumar P,Reithofer V,Reisinger M,Wallner S,Pavkov-Keller T,Macheroux P,Gruber K

Molecular simulations reveal that the long range fluctuations of human DPP III change upon ligand binding.
Molecular bioSystems11(11)3068-80(2015 Nov)
Tomi? A,Berynskyy M,Wade RC,Tomi? S

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DPP3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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