ZBED6 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ZBED6
Entrez Gene ID	100381270
Full Name	zinc finger BED-type containing 6
Synonyms	MGR
General protein information	Preferred Names zinc finger BED-type containing 6 Names zinc finger BED domain-containing protein 6
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q32.1
Summary	The protein encoded by this transposon-derived intronless gene is a transcriptional repressor that binds to the consensus sequence 5'-GCTCGC-3'. The encoded protein has been shown to repress IGF2 transcription. This gene is located within the first intron of the ZC3H11A gene. [provided by RefSeq, Jul 2016].
Disorder MIM:	613512

mRNA and Protein(s)

mRNA	Protein	Name
NM_001174108.1	NP_001167579.1	zinc finger BED domain-containing protein 6
NM_001174108.2	NP_001167579.1	zinc finger BED domain-containing protein 6

Pathways from BioSystems

Homologies

Homo sapiens (human)	ZBED6	NP_001167579.1
	ZBED6	XP_002802039.1
Canis lupus familiaris (dog)	ZBED6	XP_005640822.1
Bos taurus (cattle)	ZBED6	XP_003587091.1
Mus musculus (house mouse)	Zbed6	NP_001160024.1
Xenopus tropicalis (tropical clawed frog)	LOC101730718	XP_004919610.1

Gene Ontology
Bibliography

Related articles in PubMed

Transcriptional modulator ZBED6 affects cell cycle and growth of human colorectal cancer cells.
Akhtar Ali M, Younis S, Wallerman O, Gupta R, Andersson L, Sj?blom T
Proceedings of the National Academy of Sciences of the United States of America112(25)7743-8(2015 Jun)

Transcription factor ZBED6 affects gene expression, proliferation, and cell death in pancreatic beta cells.
Wang X, Jiang L, Wallerman O, Engstr?m U, Ameur A, Gupta RK, Qi Y, Andersson L, Welsh N
Proceedings of the National Academy of Sciences of the United States of America110(40)15997-6002(2013 Oct)

ZBED evolution: repeated utilization of DNA transposons as regulators of diverse host functions.
Hayward A, Ghazal A, Andersson G, Andersson L, Jern P
PloS one8(3)e59940(2013)

A domesticated transposon mediates the effects of a single-nucleotide polymorphism responsible for enhanced muscle growth.
Butter F, Kappei D, Buchholz F, Vermeulen M, Mann M
EMBO reports11(4)305-11(2010 Apr)

ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth.
Markljung E, Jiang L, Jaffe JD, Mikkelsen TS, Wallerman O, Larhammar M, Zhang X, Wang L, Saenz-Vash V, Gnirke A, Lindroth AM, Barr?s R, Yan J, Str?mberg S, De S, Pont?n F, Lander ES, Carr SA, Zierath JR, Kullander K, Wadelius C, Lindblad-Toh K, Andersson G, Hj?lm G, Andersson L
PLoS biology7(12)e1000256(2009 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

results of this study show that the effect of ZBED6 on tumor development depends on the genetic background and the transcriptional state of its target genes
Title: Transcriptional modulator ZBED6 affects cell cycle and growth of human colorectal cancer cells.

Mouse MGR (Zbed6) is a repressor of Igf2.
Title: A domesticated transposon mediates the effects of a single-nucleotide polymorphism responsible for enhanced muscle growth.

Silencing of Zbed6 in mouse C2C12 myoblasts affected Igf2 expression, cell proliferation, wound healing, and myotube formation.
Title: ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth.

The following ZBED6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ZBED6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu32166	NM_001174108.2 Latest version!	Homo sapiens zinc finger BED-type containing 6 (ZBED6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
View Old Accession Versions >>
OHu32166	NM_001174108.1	Homo sapiens zinc finger, BED-type containing 6 (ZBED6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ZBED6 ( NM_001174108.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001167579.1 Homo sapiens zinc finger, BED-type containing 6 (ZBED6), mRNA.

Price & Availability↑

CloneID	OHu32166
Clone ID Related Accession (Same CDS sequence)	NM_001174108.1 , NM_001174108.2
Accession Version	NM_001174108.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2940bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2014-10-31
Organism	Homo sapiens(Human)
Product	zinc finger BED domain-containing protein 6
Comment

ATGAGTGTAT GTACTCTAAG TGTACCAGTT TCTTCACTCT CTCCTGGCAG AAGATGCAAC 
ACTTTTAGTG ATTCTGGGAT TCTGGGATGT GTTCCTATTA ATTCTAATAC AGATGAAGAA 
GATGTGGTAG AGGAAAAGAT GGTAGCAGAA GGAGTGAATA AAGAGGCAAA ACAGCCTGCT 
AAAAAGAAAA GAAAGAAGGG TTTGCGAATT AAGGGGAAAA GGCGTCGAAA AAAATTGATT 
CTTGCCAAAA AGTTTAGTAA GGATTTGGGA TCTGGGAGGC CTGTTGCAGA TGCCCCTGCT 
TTGTTAGCTT CCAATGACCC TGAGCAGGAT GAAGAAAGTC TTTTTGAGAG CAATATAGAA 
AAACAGATCT ATCTACCTAG TACTAGAGCC AAGACCTCCA TTGTGTGGCA CTTCTTTCAT 
GTTGACCCCC AGTACACCTG GCGGGCCATT TGTAACCTCT GTGAGAAAAG CGTCAGCAGG 
GGTAAACCAG GTAGCCATCT TGGTACATCT ACTCTTCAAC GACATCTGCA AGCAAGGCAT 
TCACCTCATT GGACCAGGGC CAACAAGTTT GGAGTTGCTA GTGGAGAGGA GGACTTTACC 
TTGGATGTGT CTTTATCTCC CTCTTCTGGA AGCAATGGAA GCTTTGAATA TATTCCTACT 
GATCCATTAG ATGATAATAG AATGGGCAAG AAGCATGATA AATCAGCATC TGATGCCCTA 
AGGGCAGAAA GAGGGAGATT TCTCATCAAA AGTAACATTG TCAAGCATGC TTTAATTCCT 
GGAACTAGAG CCAAGACATC TGCCGTTTGG AATTTTTTTT ACACTGATCC TCAGCACATC 
TCAAGAGCTG TGTGTAATAT ATGTAAAAGA AGTGTGAGCC GGGGTAGGCC AGGGTCCCAC 
TTAGGGACTT CAACACTTCA ACGACACCTG CAAGCCACAC ATCCTATCCA TTGGGCTGTT 
GCCAACAAAG ACAGTGGTGC TGTTGCAAAT GGATTAGATG AAGCTGAGAC TGAGAGAAGT 
GATCTCTTGA GTGATACCTT GCATGGAGAA AAGTCTACAG GCAGCCAAGA TTTAACAGCT 
GAGGACCTTA GTGACTCTGA TTCAGATGAA CCTATGTTAG AGGTTGAAAA CAGATCTGAA 
AGTCCTATTC CCGTTGCAGA GCAAGGCACT CTGATGCGTG CGCAGGAGAG AGAAACAACA 
TGTTGTGGAA ATCCAGTCTC AAGTCACATA AGTCAGGCAA TTATCCAAAT GATTGTGGAG 
GATATGCATC CTTACAACTA TTTCTCAACC CCAGCCTTTC AGAGGTTCAT GCAGATTGTG 
GCCCCTGATT ATAGGTTGCC ATCAGAGACT TACTTTTTCA CTAAGGCTGT ACCTCAGTTA 
TATGATTGTG TCAGAGAAAA AATTTTCTTA ACTTTAGAGA ATGTTCAAAG CCAAAAGATA 
CACCTGACTG TTGACATATG GACCCATGAC CCATCCACTG ACTATTTTAT TGTGACTGTA 
CACTGGGTTT CTTTGGAAAC TGCGTCTTTT CTCAATAATG GCAGGATCCC CGATTTTAGA 
AAGTGGGCAG TGCTTTGTGT TACAGGTTTG GCTAAAGACT GTTTGATAAC CAATATTTTA 
CAAGAATTAA ATGACCAGAT TGGTCTGTGG CTTTCTCCAA ATTTCCTTAT CCCTAGCTTC 
ATTGTTTCTG ACAATTCCTC TAATGTGGTA CATGCAATCA AAGATGGTGG TTTTACCCAT 
GTGCCATGCT TCCTGCATTG TTTAAATATG GTCATTCAGG ACTTTTTCTG CGAGCACAAA 
AGCATTGAGA ATATGTTAGT GGCTGCCAGG AAAACTTGTC ATCATTTTAG TCATTCGGTC 
AAGGCCCGTC AGATACTGCA AGAGTTCCAA AATGATCACC AACTTCCATG GAAGAATTTG 
AAGCAGGACG AAACTGGCCA TTGGATTTCT ACTTTTTATA TGTTAAAATG GCTCTTGGAG 
CATTGCTACT CAGTTCACCA TAGTCTTGGT AGAGCCAGTG GAGTTGTGCT CACCTCCCTT 
CAGTGGACTC TAATGACTTA TGTTTGTGAT ATTCTTAAGC CATTTGAGGA GGCTACCCAG 
AAAGTGAGCG TGAAGACCGC AGGATTGAAT CAGGTGCTAC CCCTAATCCA TCATCTACTC 
CTTTCCCTGC AGAAACTCAG AGAAGATTTT CAAGTCAGAG GTATTACTCA GGCCCTCAAT 
CTGGTGGATA GTTTATCTCT GAAACTTGAA ACAGATACCC TACTAAGTGC CATGCTTAAA 
TCCAAGCCCT GTATCTTGGC TACTTTGTTA GATCCTTGCT TTAAAAACAG TTTGGAAGAC 
TTTTTTCCTC AAGGTGCTGA TTTAGAAACT TATAAGCAGT TCCTTGCAGA AGAGGTCTGT 
AATTATATGG AATCTTCACC AGAGATCTGC CAAATTCCAA CTTCAGAAGC TTCTTGTCCC 
TCAGTTACAG TGGGAGCTGA TTCATTTACC TCATCTCTAA AAGAAGGCAC CTCCAGTTCA 
GGTTCTGTTG ATAGCTCAGC TGTAGACAAT GTTGCCCTTG GAAGCAAAAG CTTCATGTTC 
CCTTCTGCTG TAGCAGTTGT GGATGAGTAC TTCAAAGAGA AGTATTCAGA GTTCTCAGGA 
GGTGATGACC CTTTAATTTA CTGGCAGAGG AAGATAAGCA TATGGCCGGC TTTGACCCAG 
GTTGCCATCC AGTATCTAAG TTGCCCCATG TGTAGTTGGC AATCTGAATG TATCTTTACT 
AAAAATAGCC ACTTTCATCC AAAACAGATC ATGAGCCTGG ACTTTGACAA TATAGAACAA 
CTGATGTTTC TGAAAATGAA CTTGAAAAAT GTTAACTACG ATTATTCTAC GTTGGTTCTG 
AGCTGGGATC CTGAGCAGAA TGAAGTTGTT CAAAGCAGTG AAAAAGAAAT ACTGCCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

NP_001167579.1

Translation

MSVCTLSVPVSSLSPGRRCNTFSDSGILGCVPINSNTDEEDVVEEKMVAEGVNKEAKQPAKKKRKKGLRIKGKRRRKKLILAKKFSKDLGSGRPVADAPALLASNDPEQDEESLFESNIEKQIYLPSTRAKTSIVWHFFHVDPQYTWRAICNLCEKSVSRGKPGSHLGTSTLQRHLQARHSPHWTRANKFGVASGEEDFTLDVSLSPSSGSNGSFEYIPTDPLDDNRMGKKHDKSASDALRAERGRFLIKSNIVKHALIPGTRAKTSAVWNFFYTDPQHISRAVCNICKRSVSRGRPGSHLGTSTLQRHLQATHPIHWAVANKDSGAVANGLDEAETERSDLLSDTLHGEKSTGSQDLTAEDLSDSDSDEPMLEVENRSESPIPVAEQGTLMRAQERETTCCGNPVSSHISQAIIQMIVEDMHPYNYFSTPAFQRFMQIVAPDYRLPSETYFFTKAVPQLYDCVREKIFLTLENVQSQKIHLTVDIWTHDPSTDYFIVTVHWVSLETASFLNNGRIPDFRKWAVLCVTGLAKDCLITNILQELNDQIGLWLSPNFLIPSFIVSDNSSNVVHAIKDGGFTHVPCFLHCLNMVIQDFFCEHKSIENMLVAARKTCHHFSHSVKARQILQEFQNDHQLPWKNLKQDETGHWISTFYMLKWLLEHCYSVHHSLGRASGVVLTSLQWTLMTYVCDILKPFEEATQKVSVKTAGLNQVLPLIHHLLLSLQKLREDFQVRGITQALNLVDSLSLKLETDTLLSAMLKSKPCILATLLDPCFKNSLEDFFPQGADLETYKQFLAEEVCNYMESSPEICQIPTSEASCPSVTVGADSFTSSLKEGTSSSGSVDSSAVDNVALGSKSFMFPSAVAVVDEYFKEKYSEFSGGDDPLIYWQRKISIWPALTQVAIQYLSCPMCSWQSECIFTKNSHFHPKQIMSLDFDNIEQLMFLKMNLKNVNYDYSTLVLSWDPEQNEVVQSSEKEILP

Target ORF information:

RefSeq Version	NM_001174108.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens zinc finger, BED-type containing 6 (ZBED6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001174108.1

ORF Insert Sequence:

ATGAGTGTAT GTACTCTAAG TGTACCAGTT TCTTCACTCT CTCCTGGCAG AAGATGCAAC 
ACTTTTAGTG ATTCTGGGAT TCTGGGATGT GTTCCTATTA ATTCTAATAC AGATGAAGAA 
GATGTGGTAG AGGAAAAGAT GGTAGCAGAA GGAGTGAATA AAGAGGCAAA ACAGCCTGCT 
AAAAAGAAAA GAAAGAAGGG TTTGCGAATT AAGGGGAAAA GGCGTCGAAA AAAATTGATT 
CTTGCCAAAA AGTTTAGTAA GGATTTGGGA TCTGGGAGGC CTGTTGCAGA TGCCCCTGCT 
TTGTTAGCTT CCAATGACCC TGAGCAGGAT GAAGAAAGTC TTTTTGAGAG CAATATAGAA 
AAACAGATCT ATCTACCTAG TACTAGAGCC AAGACCTCCA TTGTGTGGCA CTTCTTTCAT 
GTTGACCCCC AGTACACCTG GCGGGCCATT TGTAACCTCT GTGAGAAAAG CGTCAGCAGG 
GGTAAACCAG GTAGCCATCT TGGTACATCT ACTCTTCAAC GACATCTGCA AGCAAGGCAT 
TCACCTCATT GGACCAGGGC CAACAAGTTT GGAGTTGCTA GTGGAGAGGA GGACTTTACC 
TTGGATGTGT CTTTATCTCC CTCTTCTGGA AGCAATGGAA GCTTTGAATA TATTCCTACT 
GATCCATTAG ATGATAATAG AATGGGCAAG AAGCATGATA AATCAGCATC TGATGCCCTA 
AGGGCAGAAA GAGGGAGATT TCTCATCAAA AGTAACATTG TCAAGCATGC TTTAATTCCT 
GGAACTAGAG CCAAGACATC TGCCGTTTGG AATTTTTTTT ACACTGATCC TCAGCACATC 
TCAAGAGCTG TGTGTAATAT ATGTAAAAGA AGTGTGAGCC GGGGTAGGCC AGGGTCCCAC 
TTAGGGACTT CAACACTTCA ACGACACCTG CAAGCCACAC ATCCTATCCA TTGGGCTGTT 
GCCAACAAAG ACAGTGGTGC TGTTGCAAAT GGATTAGATG AAGCTGAGAC TGAGAGAAGT 
GATCTCTTGA GTGATACCTT GCATGGAGAA AAGTCTACAG GCAGCCAAGA TTTAACAGCT 
GAGGACCTTA GTGACTCTGA TTCAGATGAA CCTATGTTAG AGGTTGAAAA CAGATCTGAA 
AGTCCTATTC CCGTTGCAGA GCAAGGCACT CTGATGCGTG CGCAGGAGAG AGAAACAACA 
TGTTGTGGAA ATCCAGTCTC AAGTCACATA AGTCAGGCAA TTATCCAAAT GATTGTGGAG 
GATATGCATC CTTACAACTA TTTCTCAACC CCAGCCTTTC AGAGGTTCAT GCAGATTGTG 
GCCCCTGATT ATAGGTTGCC ATCAGAGACT TACTTTTTCA CTAAGGCTGT ACCTCAGTTA 
TATGATTGTG TCAGAGAAAA AATTTTCTTA ACTTTAGAGA ATGTTCAAAG CCAAAAGATA 
CACCTGACTG TTGACATATG GACCCATGAC CCATCCACTG ACTATTTTAT TGTGACTGTA 
CACTGGGTTT CTTTGGAAAC TGCGTCTTTT CTCAATAATG GCAGGATCCC CGATTTTAGA 
AAGTGGGCAG TGCTTTGTGT TACAGGTTTG GCTAAAGACT GTTTGATAAC CAATATTTTA 
CAAGAATTAA ATGACCAGAT TGGTCTGTGG CTTTCTCCAA ATTTCCTTAT CCCTAGCTTC 
ATTGTTTCTG ACAATTCCTC TAATGTGGTA CATGCAATCA AAGATGGTGG TTTTACCCAT 
GTGCCATGCT TCCTGCATTG TTTAAATATG GTCATTCAGG ACTTTTTCTG CGAGCACAAA 
AGCATTGAGA ATATGTTAGT GGCTGCCAGG AAAACTTGTC ATCATTTTAG TCATTCGGTC 
AAGGCCCGTC AGATACTGCA AGAGTTCCAA AATGATCACC AACTTCCATG GAAGAATTTG 
AAGCAGGACG AAACTGGCCA TTGGATTTCT ACTTTTTATA TGTTAAAATG GCTCTTGGAG 
CATTGCTACT CAGTTCACCA TAGTCTTGGT AGAGCCAGTG GAGTTGTGCT CACCTCCCTT 
CAGTGGACTC TAATGACTTA TGTTTGTGAT ATTCTTAAGC CATTTGAGGA GGCTACCCAG 
AAAGTGAGCG TGAAGACCGC AGGATTGAAT CAGGTGCTAC CCCTAATCCA TCATCTACTC 
CTTTCCCTGC AGAAACTCAG AGAAGATTTT CAAGTCAGAG GTATTACTCA GGCCCTCAAT 
CTGGTGGATA GTTTATCTCT GAAACTTGAA ACAGATACCC TACTAAGTGC CATGCTTAAA 
TCCAAGCCCT GTATCTTGGC TACTTTGTTA GATCCTTGCT TTAAAAACAG TTTGGAAGAC 
TTTTTTCCTC AAGGTGCTGA TTTAGAAACT TATAAGCAGT TCCTTGCAGA AGAGGTCTGT 
AATTATATGG AATCTTCACC AGAGATCTGC CAAATTCCAA CTTCAGAAGC TTCTTGTCCC 
TCAGTTACAG TGGGAGCTGA TTCATTTACC TCATCTCTAA AAGAAGGCAC CTCCAGTTCA 
GGTTCTGTTG ATAGCTCAGC TGTAGACAAT GTTGCCCTTG GAAGCAAAAG CTTCATGTTC 
CCTTCTGCTG TAGCAGTTGT GGATGAGTAC TTCAAAGAGA AGTATTCAGA GTTCTCAGGA 
GGTGATGACC CTTTAATTTA CTGGCAGAGG AAGATAAGCA TATGGCCGGC TTTGACCCAG 
GTTGCCATCC AGTATCTAAG TTGCCCCATG TGTAGTTGGC AATCTGAATG TATCTTTACT 
AAAAATAGCC ACTTTCATCC AAAACAGATC ATGAGCCTGG ACTTTGACAA TATAGAACAA 
CTGATGTTTC TGAAAATGAA CTTGAAAAAT GTTAACTACG ATTATTCTAC GTTGGTTCTG 
AGCTGGGATC CTGAGCAGAA TGAAGTTGTT CAAAGCAGTG AAAAAGAAAT ACTGCCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ZBED6 ( NM_001174108.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001167579.1 Homo sapiens zinc finger BED-type containing 6 (ZBED6), mRNA.

Price & Availability↑

CloneID	OHu32166
Clone ID Related Accession (Same CDS sequence)	NM_001174108.1 , NM_001174108.2
Accession Version	NM_001174108.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2940bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-03
Organism	Homo sapiens(human)
Product	zinc finger BED domain-containing protein 6
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC114402.2. On Jul 10, 2016 this sequence version replaced NM_001174108.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence because no single transcript was available for the full length of the gene. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript is intronless :: SRR1163655.143051.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGAGTGTAT GTACTCTAAG TGTACCAGTT TCTTCACTCT CTCCTGGCAG AAGATGCAAC 
ACTTTTAGTG ATTCTGGGAT TCTGGGATGT GTTCCTATTA ATTCTAATAC AGATGAAGAA 
GATGTGGTAG AGGAAAAGAT GGTAGCAGAA GGAGTGAATA AAGAGGCAAA ACAGCCTGCT 
AAAAAGAAAA GAAAGAAGGG TTTGCGAATT AAGGGGAAAA GGCGTCGAAA AAAATTGATT 
CTTGCCAAAA AGTTTAGTAA GGATTTGGGA TCTGGGAGGC CTGTTGCAGA TGCCCCTGCT 
TTGTTAGCTT CCAATGACCC TGAGCAGGAT GAAGAAAGTC TTTTTGAGAG CAATATAGAA 
AAACAGATCT ATCTACCTAG TACTAGAGCC AAGACCTCCA TTGTGTGGCA CTTCTTTCAT 
GTTGACCCCC AGTACACCTG GCGGGCCATT TGTAACCTCT GTGAGAAAAG CGTCAGCAGG 
GGTAAACCAG GTAGCCATCT TGGTACATCT ACTCTTCAAC GACATCTGCA AGCAAGGCAT 
TCACCTCATT GGACCAGGGC CAACAAGTTT GGAGTTGCTA GTGGAGAGGA GGACTTTACC 
TTGGATGTGT CTTTATCTCC CTCTTCTGGA AGCAATGGAA GCTTTGAATA TATTCCTACT 
GATCCATTAG ATGATAATAG AATGGGCAAG AAGCATGATA AATCAGCATC TGATGCCCTA 
AGGGCAGAAA GAGGGAGATT TCTCATCAAA AGTAACATTG TCAAGCATGC TTTAATTCCT 
GGAACTAGAG CCAAGACATC TGCCGTTTGG AATTTTTTTT ACACTGATCC TCAGCACATC 
TCAAGAGCTG TGTGTAATAT ATGTAAAAGA AGTGTGAGCC GGGGTAGGCC AGGGTCCCAC 
TTAGGGACTT CAACACTTCA ACGACACCTG CAAGCCACAC ATCCTATCCA TTGGGCTGTT 
GCCAACAAAG ACAGTGGTGC TGTTGCAAAT GGATTAGATG AAGCTGAGAC TGAGAGAAGT 
GATCTCTTGA GTGATACCTT GCATGGAGAA AAGTCTACAG GCAGCCAAGA TTTAACAGCT 
GAGGACCTTA GTGACTCTGA TTCAGATGAA CCTATGTTAG AGGTTGAAAA CAGATCTGAA 
AGTCCTATTC CCGTTGCAGA GCAAGGCACT CTGATGCGTG CGCAGGAGAG AGAAACAACA 
TGTTGTGGAA ATCCAGTCTC AAGTCACATA AGTCAGGCAA TTATCCAAAT GATTGTGGAG 
GATATGCATC CTTACAACTA TTTCTCAACC CCAGCCTTTC AGAGGTTCAT GCAGATTGTG 
GCCCCTGATT ATAGGTTGCC ATCAGAGACT TACTTTTTCA CTAAGGCTGT ACCTCAGTTA 
TATGATTGTG TCAGAGAAAA AATTTTCTTA ACTTTAGAGA ATGTTCAAAG CCAAAAGATA 
CACCTGACTG TTGACATATG GACCCATGAC CCATCCACTG ACTATTTTAT TGTGACTGTA 
CACTGGGTTT CTTTGGAAAC TGCGTCTTTT CTCAATAATG GCAGGATCCC CGATTTTAGA 
AAGTGGGCAG TGCTTTGTGT TACAGGTTTG GCTAAAGACT GTTTGATAAC CAATATTTTA 
CAAGAATTAA ATGACCAGAT TGGTCTGTGG CTTTCTCCAA ATTTCCTTAT CCCTAGCTTC 
ATTGTTTCTG ACAATTCCTC TAATGTGGTA CATGCAATCA AAGATGGTGG TTTTACCCAT 
GTGCCATGCT TCCTGCATTG TTTAAATATG GTCATTCAGG ACTTTTTCTG CGAGCACAAA 
AGCATTGAGA ATATGTTAGT GGCTGCCAGG AAAACTTGTC ATCATTTTAG TCATTCGGTC 
AAGGCCCGTC AGATACTGCA AGAGTTCCAA AATGATCACC AACTTCCATG GAAGAATTTG 
AAGCAGGACG AAACTGGCCA TTGGATTTCT ACTTTTTATA TGTTAAAATG GCTCTTGGAG 
CATTGCTACT CAGTTCACCA TAGTCTTGGT AGAGCCAGTG GAGTTGTGCT CACCTCCCTT 
CAGTGGACTC TAATGACTTA TGTTTGTGAT ATTCTTAAGC CATTTGAGGA GGCTACCCAG 
AAAGTGAGCG TGAAGACCGC AGGATTGAAT CAGGTGCTAC CCCTAATCCA TCATCTACTC 
CTTTCCCTGC AGAAACTCAG AGAAGATTTT CAAGTCAGAG GTATTACTCA GGCCCTCAAT 
CTGGTGGATA GTTTATCTCT GAAACTTGAA ACAGATACCC TACTAAGTGC CATGCTTAAA 
TCCAAGCCCT GTATCTTGGC TACTTTGTTA GATCCTTGCT TTAAAAACAG TTTGGAAGAC 
TTTTTTCCTC AAGGTGCTGA TTTAGAAACT TATAAGCAGT TCCTTGCAGA AGAGGTCTGT 
AATTATATGG AATCTTCACC AGAGATCTGC CAAATTCCAA CTTCAGAAGC TTCTTGTCCC 
TCAGTTACAG TGGGAGCTGA TTCATTTACC TCATCTCTAA AAGAAGGCAC CTCCAGTTCA 
GGTTCTGTTG ATAGCTCAGC TGTAGACAAT GTTGCCCTTG GAAGCAAAAG CTTCATGTTC 
CCTTCTGCTG TAGCAGTTGT GGATGAGTAC TTCAAAGAGA AGTATTCAGA GTTCTCAGGA 
GGTGATGACC CTTTAATTTA CTGGCAGAGG AAGATAAGCA TATGGCCGGC TTTGACCCAG 
GTTGCCATCC AGTATCTAAG TTGCCCCATG TGTAGTTGGC AATCTGAATG TATCTTTACT 
AAAAATAGCC ACTTTCATCC AAAACAGATC ATGAGCCTGG ACTTTGACAA TATAGAACAA 
CTGATGTTTC TGAAAATGAA CTTGAAAAAT GTTAACTACG ATTATTCTAC GTTGGTTCTG 
AGCTGGGATC CTGAGCAGAA TGAAGTTGTT CAAAGCAGTG AAAAAGAAAT ACTGCCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001167579.1
CDS	1..2940
Translation	MSVCTLSVPVSSLSPGRRCNTFSDSGILGCVPINSNTDEEDVVEEKMVAEGVNKEAKQPAKKKRKKGLRIKGKRRRKKLILAKKFSKDLGSGRPVADAPALLASNDPEQDEESLFESNIEKQIYLPSTRAKTSIVWHFFHVDPQYTWRAICNLCEKSVSRGKPGSHLGTSTLQRHLQARHSPHWTRANKFGVASGEEDFTLDVSLSPSSGSNGSFEYIPTDPLDDNRMGKKHDKSASDALRAERGRFLIKSNIVKHALIPGTRAKTSAVWNFFYTDPQHISRAVCNICKRSVSRGRPGSHLGTSTLQRHLQATHPIHWAVANKDSGAVANGLDEAETERSDLLSDTLHGEKSTGSQDLTAEDLSDSDSDEPMLEVENRSESPIPVAEQGTLMRAQERETTCCGNPVSSHISQAIIQMIVEDMHPYNYFSTPAFQRFMQIVAPDYRLPSETYFFTKAVPQLYDCVREKIFLTLENVQSQKIHLTVDIWTHDPSTDYFIVTVHWVSLETASFLNNGRIPDFRKWAVLCVTGLAKDCLITNILQELNDQIGLWLSPNFLIPSFIVSDNSSNVVHAIKDGGFTHVPCFLHCLNMVIQDFFCEHKSIENMLVAARKTCHHFSHSVKARQILQEFQNDHQLPWKNLKQDETGHWISTFYMLKWLLEHCYSVHHSLGRASGVVLTSLQWTLMTYVCDILKPFEEATQKVSVKTAGLNQVLPLIHHLLLSLQKLREDFQVRGITQALNLVDSLSLKLETDTLLSAMLKSKPCILATLLDPCFKNSLEDFFPQGADLETYKQFLAEEVCNYMESSPEICQIPTSEASCPSVTVGADSFTSSLKEGTSSSGSVDSSAVDNVALGSKSFMFPSAVAVVDEYFKEKYSEFSGGDDPLIYWQRKISIWPALTQVAIQYLSCPMCSWQSECIFTKNSHFHPKQIMSLDFDNIEQLMFLKMNLKNVNYDYSTLVLSWDPEQNEVVQSSEKEILP

Target ORF information:

RefSeq Version	NM_001174108.2
Organism	Homo sapiens(human)
Definition	Homo sapiens zinc finger BED-type containing 6 (ZBED6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001174108.2

ORF Insert Sequence:

ATGAGTGTAT GTACTCTAAG TGTACCAGTT TCTTCACTCT CTCCTGGCAG AAGATGCAAC 
ACTTTTAGTG ATTCTGGGAT TCTGGGATGT GTTCCTATTA ATTCTAATAC AGATGAAGAA 
GATGTGGTAG AGGAAAAGAT GGTAGCAGAA GGAGTGAATA AAGAGGCAAA ACAGCCTGCT 
AAAAAGAAAA GAAAGAAGGG TTTGCGAATT AAGGGGAAAA GGCGTCGAAA AAAATTGATT 
CTTGCCAAAA AGTTTAGTAA GGATTTGGGA TCTGGGAGGC CTGTTGCAGA TGCCCCTGCT 
TTGTTAGCTT CCAATGACCC TGAGCAGGAT GAAGAAAGTC TTTTTGAGAG CAATATAGAA 
AAACAGATCT ATCTACCTAG TACTAGAGCC AAGACCTCCA TTGTGTGGCA CTTCTTTCAT 
GTTGACCCCC AGTACACCTG GCGGGCCATT TGTAACCTCT GTGAGAAAAG CGTCAGCAGG 
GGTAAACCAG GTAGCCATCT TGGTACATCT ACTCTTCAAC GACATCTGCA AGCAAGGCAT 
TCACCTCATT GGACCAGGGC CAACAAGTTT GGAGTTGCTA GTGGAGAGGA GGACTTTACC 
TTGGATGTGT CTTTATCTCC CTCTTCTGGA AGCAATGGAA GCTTTGAATA TATTCCTACT 
GATCCATTAG ATGATAATAG AATGGGCAAG AAGCATGATA AATCAGCATC TGATGCCCTA 
AGGGCAGAAA GAGGGAGATT TCTCATCAAA AGTAACATTG TCAAGCATGC TTTAATTCCT 
GGAACTAGAG CCAAGACATC TGCCGTTTGG AATTTTTTTT ACACTGATCC TCAGCACATC 
TCAAGAGCTG TGTGTAATAT ATGTAAAAGA AGTGTGAGCC GGGGTAGGCC AGGGTCCCAC 
TTAGGGACTT CAACACTTCA ACGACACCTG CAAGCCACAC ATCCTATCCA TTGGGCTGTT 
GCCAACAAAG ACAGTGGTGC TGTTGCAAAT GGATTAGATG AAGCTGAGAC TGAGAGAAGT 
GATCTCTTGA GTGATACCTT GCATGGAGAA AAGTCTACAG GCAGCCAAGA TTTAACAGCT 
GAGGACCTTA GTGACTCTGA TTCAGATGAA CCTATGTTAG AGGTTGAAAA CAGATCTGAA 
AGTCCTATTC CCGTTGCAGA GCAAGGCACT CTGATGCGTG CGCAGGAGAG AGAAACAACA 
TGTTGTGGAA ATCCAGTCTC AAGTCACATA AGTCAGGCAA TTATCCAAAT GATTGTGGAG 
GATATGCATC CTTACAACTA TTTCTCAACC CCAGCCTTTC AGAGGTTCAT GCAGATTGTG 
GCCCCTGATT ATAGGTTGCC ATCAGAGACT TACTTTTTCA CTAAGGCTGT ACCTCAGTTA 
TATGATTGTG TCAGAGAAAA AATTTTCTTA ACTTTAGAGA ATGTTCAAAG CCAAAAGATA 
CACCTGACTG TTGACATATG GACCCATGAC CCATCCACTG ACTATTTTAT TGTGACTGTA 
CACTGGGTTT CTTTGGAAAC TGCGTCTTTT CTCAATAATG GCAGGATCCC CGATTTTAGA 
AAGTGGGCAG TGCTTTGTGT TACAGGTTTG GCTAAAGACT GTTTGATAAC CAATATTTTA 
CAAGAATTAA ATGACCAGAT TGGTCTGTGG CTTTCTCCAA ATTTCCTTAT CCCTAGCTTC 
ATTGTTTCTG ACAATTCCTC TAATGTGGTA CATGCAATCA AAGATGGTGG TTTTACCCAT 
GTGCCATGCT TCCTGCATTG TTTAAATATG GTCATTCAGG ACTTTTTCTG CGAGCACAAA 
AGCATTGAGA ATATGTTAGT GGCTGCCAGG AAAACTTGTC ATCATTTTAG TCATTCGGTC 
AAGGCCCGTC AGATACTGCA AGAGTTCCAA AATGATCACC AACTTCCATG GAAGAATTTG 
AAGCAGGACG AAACTGGCCA TTGGATTTCT ACTTTTTATA TGTTAAAATG GCTCTTGGAG 
CATTGCTACT CAGTTCACCA TAGTCTTGGT AGAGCCAGTG GAGTTGTGCT CACCTCCCTT 
CAGTGGACTC TAATGACTTA TGTTTGTGAT ATTCTTAAGC CATTTGAGGA GGCTACCCAG 
AAAGTGAGCG TGAAGACCGC AGGATTGAAT CAGGTGCTAC CCCTAATCCA TCATCTACTC 
CTTTCCCTGC AGAAACTCAG AGAAGATTTT CAAGTCAGAG GTATTACTCA GGCCCTCAAT 
CTGGTGGATA GTTTATCTCT GAAACTTGAA ACAGATACCC TACTAAGTGC CATGCTTAAA 
TCCAAGCCCT GTATCTTGGC TACTTTGTTA GATCCTTGCT TTAAAAACAG TTTGGAAGAC 
TTTTTTCCTC AAGGTGCTGA TTTAGAAACT TATAAGCAGT TCCTTGCAGA AGAGGTCTGT 
AATTATATGG AATCTTCACC AGAGATCTGC CAAATTCCAA CTTCAGAAGC TTCTTGTCCC 
TCAGTTACAG TGGGAGCTGA TTCATTTACC TCATCTCTAA AAGAAGGCAC CTCCAGTTCA 
GGTTCTGTTG ATAGCTCAGC TGTAGACAAT GTTGCCCTTG GAAGCAAAAG CTTCATGTTC 
CCTTCTGCTG TAGCAGTTGT GGATGAGTAC TTCAAAGAGA AGTATTCAGA GTTCTCAGGA 
GGTGATGACC CTTTAATTTA CTGGCAGAGG AAGATAAGCA TATGGCCGGC TTTGACCCAG 
GTTGCCATCC AGTATCTAAG TTGCCCCATG TGTAGTTGGC AATCTGAATG TATCTTTACT 
AAAAATAGCC ACTTTCATCC AAAACAGATC ATGAGCCTGG ACTTTGACAA TATAGAACAA 
CTGATGTTTC TGAAAATGAA CTTGAAAAAT GTTAACTACG ATTATTCTAC GTTGGTTCTG 
AGCTGGGATC CTGAGCAGAA TGAAGTTGTT CAAAGCAGTG AAAAAGAAAT ACTGCCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Transcriptional modulator ZBED6 affects cell cycle and growth of human colorectal cancer cells.
Proceedings of the National Academy of Sciences of the United States of America112(25)7743-8(2015 Jun)
Akhtar Ali M,Younis S,Wallerman O,Gupta R,Andersson L,Sj?blom T

Transcription factor ZBED6 affects gene expression, proliferation, and cell death in pancreatic beta cells.
Proceedings of the National Academy of Sciences of the United States of America110(40)15997-6002(2013 Oct)
Wang X,Jiang L,Wallerman O,Engstr?m U,Ameur A,Gupta RK,Qi Y,Andersson L,Welsh N

ZBED evolution: repeated utilization of DNA transposons as regulators of diverse host functions.
PloS one8(3)e59940(2013)
Hayward A,Ghazal A,Andersson G,Andersson L,Jern P

A domesticated transposon mediates the effects of a single-nucleotide polymorphism responsible for enhanced muscle growth.
EMBO reports11(4)305-11(2010 Apr)
Butter F,Kappei D,Buchholz F,Vermeulen M,Mann M

ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth.
PLoS biology7(12)e1000256(2009 Dec)
Markljung E,Jiang L,Jaffe JD,Mikkelsen TS,Wallerman O,Larhammar M,Zhang X,Wang L,Saenz-Vash V,Gnirke A,Lindroth AM,Barr?s R,Yan J,Str?mberg S,De S,Pont?n F,Lander ES,Carr SA,Zierath JR,Kullander K,Wadelius C,Lindblad-Toh K,Andersson G,Hj?lm G,Andersson L

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ZBED6 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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