PARP2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PARP2
Entrez Gene ID	10038
Full Name	poly(ADP-ribose) polymerase 2
Synonyms	ADPRT2,ADPRTL2,ADPRTL3,ARTD2,PARP-2,pADPRT-2
General protein information	Preferred Names poly(ADP-ribose) polymerase 2 Names poly [ADP-ribose] polymerase 2 ADP-ribosyltransferase (NAD+; poly(ADP-ribose) polymerase)-like 2 ADP-ribosyltransferase diphtheria toxin-like 2 ADPRT-2 NAD(+) ADP-ribosyltransferase 2 hPARP-2 poly (ADP-ribose) polymerase family, member 2 poly (ADP-ribosyl) transferase-like 2 poly[ADP-ribose] synthase 2 poly[ADP-ribose] synthetase 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 14 Map Location: 14q11.2
Summary	This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jul 2008].
Disorder MIM:	607725

mRNA and Protein(s)

mRNA	Protein	Name
XM_005267247.3	XP_005267304.1	poly [ADP-ribose] polymerase 2 isoform X1
NM_005484.3	NP_005475.2	poly [ADP-ribose] polymerase 2 isoform 1
NM_001042618.1	NP_001036083.1	poly [ADP-ribose] polymerase 2 isoform 2
XM_017020912.1	XP_016876401.1	poly [ADP-ribose] polymerase 2 isoform X2

Pathways from BioSystems

Homologies

Arabidopsis thaliana (thale cress)	PP	NP_192148.2
Canis lupus familiaris (dog)	PARP2	XP_532616.3
Bos taurus (cattle)	PARP2	XP_003586589.1
Rattus norvegicus (Norway rat)	Parp2	NP_001099500.1
Oryza sativa (rice)	Os01g0351100	NP_001042983.2
Pan troglodytes (chimpanzee)	PARP2	XP_001137649.1
Mus musculus (house mouse)	Parp2	NP_033762.1
Xenopus tropicalis (tropical clawed frog)	parp2	XP_002934323.2
Homo sapiens (human)	PARP2	NP_005475.2
	PARP2	XP_001088314.1
Danio rerio (zebrafish)	parp2	NP_001191199.1

Gene Ontology
Bibliography

Related articles in PubMed

PARP2 controls double-strand break repair pathway choice by limiting 53BP1 accumulation at DNA damage sites and promoting end-resection.
Fouquin A, Guirouilh-Barbat J, Lopez B, Hall J, Amor-Gu?ret M, Pennaneach V
Nucleic acids research45(21)12325-12339(2017 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

PARP2 specifically limits the accumulation of the resection barrier factor 53BP1 at DNA damage sites, allowing efficient CtIP-dependent DNA end-resection
Title: PARP2 controls double-strand break repair pathway choice by limiting 53BP1 accumulation at DNA damage sites and promoting end-resection.

either PARP1 or PARP2 are sufficient for near-normal XRCC1 recruitment at oxidative single-strand breaks
Title: Overlapping roles for PARP1 and PARP2 in the recruitment of endogenous XRCC1 and PNKP into oxidized chromatin.

Studies indicate that poly(ADP-ribose) polymerase 2 (PARP2) is involved in the differentiation of several cell types, including erythrocytes, T cells and adipocytes.
Title: New directions in poly(ADP-ribose) polymerase biology.

Findings indicate that Increased poly(ADP-ribose) polymerase-2 (PARP-2) expression and loss of micrRNA miR-149 expression are involved in the pathogenesis of hepatocellular carcinomas (HCC) and are poor prognosis factors in patients with HCC.
Title: The clinicopathological significance of miR-149 and PARP-2 in hepatocellular carcinoma and their roles in chemo/radiotherapy.

Our study differentiates the functions of PARP-2 domains from those of PARP-1, the other major DDR-PARP, and highlights the specialization of the multi-domain architectures of DDR-PARPs.
Title: PARP-2 domain requirements for DNA damage-dependent activation and localization to sites of DNA damage.

The following PARP2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PARP2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18664	NM_005484.3 Latest version!	Homo sapiens poly(ADP-ribose) polymerase 2 (PARP2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$342.30 $489.00
OHu17217	NM_001042618.1 Latest version!	Homo sapiens poly(ADP-ribose) polymerase 2 (PARP2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$335.30 $479.00
OHu47470	XM_005267247.3 Latest version!	Homo sapiens poly(ADP-ribose) polymerase 2 (PARP2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu84724	XM_017020912.1 Latest version!	Homo sapiens poly(ADP-ribose) polymerase 2 (PARP2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PARP2 ( NM_005484.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_005475.2 Homo sapiens poly(ADP-ribose) polymerase 2 (PARP2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu18664
Clone ID Related Accession (Same CDS sequence)	NM_005484.3
Accession Version	NM_005484.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1752bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-18
Organism	Homo sapiens(human)
Product	poly [ADP-ribose] polymerase 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA354586.1, AK001980.1, AJ236912.1 and BU541261.1. This sequence is a reference standard in the RefSeqGene project. On Jul 28, 2006 this sequence version replaced NM_005484.2. Transcript Variant: This variant (1) encodes a longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.175761.1, SRR1660807.259111.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCGC GGCGGCGACG GAGCACCGGC GGCGGCAGGG CGAGAGCATT AAATGAAAGC 
AAAAGAGTTA ATAATGGCAA CACGGCTCCA GAAGACTCTT CCCCTGCCAA GAAAACTCGT 
AGATGCCAGA GACAGGAGTC GAAAAAGATG CCTGTGGCTG GAGGAAAAGC TAATAAGGAC 
AGGACAGAAG ACAAGCAAGA TGGTATGCCA GGAAGGTCAT GGGCCAGCAA AAGGGTCTCT 
GAATCTGTGA AGGCCTTGCT GTTAAAGGGC AAAGCTCCTG TGGACCCAGA GTGTACAGCC 
AAGGTGGGGA AGGCTCATGT GTATTGTGAA GGAAATGATG TCTATGATGT CATGCTAAAT 
CAGACCAATC TCCAGTTCAA CAACAACAAG TACTATCTGA TTCAGCTATT AGAAGATGAT 
GCCCAGAGGA ACTTCAGTGT TTGGATGAGA TGGGGCCGAG TTGGGAAAAT GGGACAGCAC 
AGCCTGGTGG CTTGTTCAGG CAATCTCAAC AAGGCCAAGG AAATCTTTCA GAAGAAATTC 
CTTGACAAAA CGAAAAACAA TTGGGAAGAT CGAGAAAAGT TTGAGAAGGT GCCTGGAAAA 
TATGATATGC TACAGATGGA CTATGCCACC AATACTCAGG ATGAAGAGGA AACAAAGAAA 
GAGGAATCTC TTAAATCTCC CTTGAAGCCA GAGTCACAGC TAGATCTTCG GGTACAGGAG 
TTAATAAAGT TGATCTGTAA TGTTCAGGCC ATGGAAGAAA TGATGATGGA AATGAAGTAT 
AATACCAAGA AAGCCCCACT TGGGAAGCTG ACAGTGGCAC AAATCAAGGC AGGTTACCAG 
TCTCTTAAGA AGATTGAGGA TTGTATTCGG GCTGGCCAGC ATGGACGAGC TCTCATGGAA 
GCATGCAATG AATTCTACAC CAGGATTCCG CATGACTTTG GACTCCGTAC TCCTCCACTA 
ATCCGGACAC AGAAGGAACT GTCAGAAAAA ATACAATTAC TAGAGGCTTT GGGAGACATT 
GAAATTGCTA TTAAGCTGGT GAAAACAGAG CTACAAAGCC CAGAACACCC ATTGGACCAA 
CACTATAGAA ACCTACATTG TGCCTTGCGC CCCCTTGACC ATGAAAGTTA TGAGTTCAAA 
GTGATTTCCC AGTACCTACA ATCTACCCAT GCTCCCACAC ACAGCGACTA TACCATGACC 
TTGCTGGATT TGTTTGAAGT GGAGAAGGAT GGTGAGAAAG AAGCCTTCAG AGAGGACCTT 
CATAACAGGA TGCTTCTATG GCATGGTTCC AGGATGAGTA ACTGGGTGGG AATCTTGAGC 
CATGGGCTTC GAATTGCCCC ACCTGAAGCT CCCATCACAG GTTACATGTT TGGGAAAGGA 
ATCTACTTTG CTGACATGTC TTCCAAGAGT GCCAATTACT GCTTTGCCTC TCGCCTAAAG 
AATACAGGAC TGCTGCTCTT ATCAGAGGTA GCTCTAGGTC AGTGTAATGA ACTACTAGAG 
GCCAATCCTA AGGCCGAAGG ATTGCTTCAA GGTAAACATA GCACCAAGGG GCTGGGCAAG 
ATGGCTCCCA GTTCTGCCCA CTTCGTCACC CTGAATGGGA GTACAGTGCC ATTAGGACCA 
GCAAGTGACA CAGGAATTCT GAATCCAGAT GGTTATACCC TCAACTACAA TGAATATATT 
GTATATAACC CCAACCAGGT CCGTATGCGG TACCTTTTAA AGGTTCAGTT TAATTTCCTT 
CAGCTGTGGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005475.2
CDS	29..1780
Translation	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW

Target ORF information:

RefSeq Version	NM_005484.3
Organism	Homo sapiens(human)
Definition	Homo sapiens poly(ADP-ribose) polymerase 2 (PARP2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005484.3

ORF Insert Sequence:

ATGGCGGCGC GGCGGCGACG GAGCACCGGC GGCGGCAGGG CGAGAGCATT AAATGAAAGC 
AAAAGAGTTA ATAATGGCAA CACGGCTCCA GAAGACTCTT CCCCTGCCAA GAAAACTCGT 
AGATGCCAGA GACAGGAGTC GAAAAAGATG CCTGTGGCTG GAGGAAAAGC TAATAAGGAC 
AGGACAGAAG ACAAGCAAGA TGGTATGCCA GGAAGGTCAT GGGCCAGCAA AAGGGTCTCT 
GAATCTGTGA AGGCCTTGCT GTTAAAGGGC AAAGCTCCTG TGGACCCAGA GTGTACAGCC 
AAGGTGGGGA AGGCTCATGT GTATTGTGAA GGAAATGATG TCTATGATGT CATGCTAAAT 
CAGACCAATC TCCAGTTCAA CAACAACAAG TACTATCTGA TTCAGCTATT AGAAGATGAT 
GCCCAGAGGA ACTTCAGTGT TTGGATGAGA TGGGGCCGAG TTGGGAAAAT GGGACAGCAC 
AGCCTGGTGG CTTGTTCAGG CAATCTCAAC AAGGCCAAGG AAATCTTTCA GAAGAAATTC 
CTTGACAAAA CGAAAAACAA TTGGGAAGAT CGAGAAAAGT TTGAGAAGGT GCCTGGAAAA 
TATGATATGC TACAGATGGA CTATGCCACC AATACTCAGG ATGAAGAGGA AACAAAGAAA 
GAGGAATCTC TTAAATCTCC CTTGAAGCCA GAGTCACAGC TAGATCTTCG GGTACAGGAG 
TTAATAAAGT TGATCTGTAA TGTTCAGGCC ATGGAAGAAA TGATGATGGA AATGAAGTAT 
AATACCAAGA AAGCCCCACT TGGGAAGCTG ACAGTGGCAC AAATCAAGGC AGGTTACCAG 
TCTCTTAAGA AGATTGAGGA TTGTATTCGG GCTGGCCAGC ATGGACGAGC TCTCATGGAA 
GCATGCAATG AATTCTACAC CAGGATTCCG CATGACTTTG GACTCCGTAC TCCTCCACTA 
ATCCGGACAC AGAAGGAACT GTCAGAAAAA ATACAATTAC TAGAGGCTTT GGGAGACATT 
GAAATTGCTA TTAAGCTGGT GAAAACAGAG CTACAAAGCC CAGAACACCC ATTGGACCAA 
CACTATAGAA ACCTACATTG TGCCTTGCGC CCCCTTGACC ATGAAAGTTA TGAGTTCAAA 
GTGATTTCCC AGTACCTACA ATCTACCCAT GCTCCCACAC ACAGCGACTA TACCATGACC 
TTGCTGGATT TGTTTGAAGT GGAGAAGGAT GGTGAGAAAG AAGCCTTCAG AGAGGACCTT 
CATAACAGGA TGCTTCTATG GCATGGTTCC AGGATGAGTA ACTGGGTGGG AATCTTGAGC 
CATGGGCTTC GAATTGCCCC ACCTGAAGCT CCCATCACAG GTTACATGTT TGGGAAAGGA 
ATCTACTTTG CTGACATGTC TTCCAAGAGT GCCAATTACT GCTTTGCCTC TCGCCTAAAG 
AATACAGGAC TGCTGCTCTT ATCAGAGGTA GCTCTAGGTC AGTGTAATGA ACTACTAGAG 
GCCAATCCTA AGGCCGAAGG ATTGCTTCAA GGTAAACATA GCACCAAGGG GCTGGGCAAG 
ATGGCTCCCA GTTCTGCCCA CTTCGTCACC CTGAATGGGA GTACAGTGCC ATTAGGACCA 
GCAAGTGACA CAGGAATTCT GAATCCAGAT GGTTATACCC TCAACTACAA TGAATATATT 
GTATATAACC CCAACCAGGT CCGTATGCGG TACCTTTTAA AGGTTCAGTT TAATTTCCTT 
CAGCTGTGGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PARP2 ( NM_001042618.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001036083.1 Homo sapiens poly(ADP-ribose) polymerase 2 (PARP2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu17217
Clone ID Related Accession (Same CDS sequence)	NM_001042618.1
Accession Version	NM_001042618.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1713bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-18
Organism	Homo sapiens(human)
Product	poly [ADP-ribose] polymerase 2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA354586.1, AJ236912.1 and BU541261.1. Transcript Variant: This variant (2) lacks an internal segment in the 5' coding region, as compared to variant 1. The reading frame is not changed but the transcript encodes 13 aa less than variant 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.489421.1, SRR1660803.165264.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCGC GGCGGCGACG GAGCACCGGC GGCGGCAGGG CGAGAGCATT AAATGAAAGC 
AAAAGAGTTA ATAATGGCAA CACGGCTCCA GAAGACTCTT CCCCTGCCAA GAAAACTCGT 
AGATGCCAGA GACAGGAGTC GAAAAAGATG CCTGTGGCTG GAGGAAAAGC TAATAAGGAC 
AGGACAGAAG ACAAGCAAGA TGAATCTGTG AAGGCCTTGC TGTTAAAGGG CAAAGCTCCT 
GTGGACCCAG AGTGTACAGC CAAGGTGGGG AAGGCTCATG TGTATTGTGA AGGAAATGAT 
GTCTATGATG TCATGCTAAA TCAGACCAAT CTCCAGTTCA ACAACAACAA GTACTATCTG 
ATTCAGCTAT TAGAAGATGA TGCCCAGAGG AACTTCAGTG TTTGGATGAG ATGGGGCCGA 
GTTGGGAAAA TGGGACAGCA CAGCCTGGTG GCTTGTTCAG GCAATCTCAA CAAGGCCAAG 
GAAATCTTTC AGAAGAAATT CCTTGACAAA ACGAAAAACA ATTGGGAAGA TCGAGAAAAG 
TTTGAGAAGG TGCCTGGAAA ATATGATATG CTACAGATGG ACTATGCCAC CAATACTCAG 
GATGAAGAGG AAACAAAGAA AGAGGAATCT CTTAAATCTC CCTTGAAGCC AGAGTCACAG 
CTAGATCTTC GGGTACAGGA GTTAATAAAG TTGATCTGTA ATGTTCAGGC CATGGAAGAA 
ATGATGATGG AAATGAAGTA TAATACCAAG AAAGCCCCAC TTGGGAAGCT GACAGTGGCA 
CAAATCAAGG CAGGTTACCA GTCTCTTAAG AAGATTGAGG ATTGTATTCG GGCTGGCCAG 
CATGGACGAG CTCTCATGGA AGCATGCAAT GAATTCTACA CCAGGATTCC GCATGACTTT 
GGACTCCGTA CTCCTCCACT AATCCGGACA CAGAAGGAAC TGTCAGAAAA AATACAATTA 
CTAGAGGCTT TGGGAGACAT TGAAATTGCT ATTAAGCTGG TGAAAACAGA GCTACAAAGC 
CCAGAACACC CATTGGACCA ACACTATAGA AACCTACATT GTGCCTTGCG CCCCCTTGAC 
CATGAAAGTT ATGAGTTCAA AGTGATTTCC CAGTACCTAC AATCTACCCA TGCTCCCACA 
CACAGCGACT ATACCATGAC CTTGCTGGAT TTGTTTGAAG TGGAGAAGGA TGGTGAGAAA 
GAAGCCTTCA GAGAGGACCT TCATAACAGG ATGCTTCTAT GGCATGGTTC CAGGATGAGT 
AACTGGGTGG GAATCTTGAG CCATGGGCTT CGAATTGCCC CACCTGAAGC TCCCATCACA 
GGTTACATGT TTGGGAAAGG AATCTACTTT GCTGACATGT CTTCCAAGAG TGCCAATTAC 
TGCTTTGCCT CTCGCCTAAA GAATACAGGA CTGCTGCTCT TATCAGAGGT AGCTCTAGGT 
CAGTGTAATG AACTACTAGA GGCCAATCCT AAGGCCGAAG GATTGCTTCA AGGTAAACAT 
AGCACCAAGG GGCTGGGCAA GATGGCTCCC AGTTCTGCCC ACTTCGTCAC CCTGAATGGG 
AGTACAGTGC CATTAGGACC AGCAAGTGAC ACAGGAATTC TGAATCCAGA TGGTTATACC 
CTCAACTACA ATGAATATAT TGTATATAAC CCCAACCAGG TCCGTATGCG GTACCTTTTA 
AAGGTTCAGT TTAATTTCCT TCAGCTGTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001036083.1
CDS	29..1741
Translation	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW

Target ORF information:

RefSeq Version	NM_001042618.1
Organism	Homo sapiens(human)
Definition	Homo sapiens poly(ADP-ribose) polymerase 2 (PARP2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001042618.1

ORF Insert Sequence:

ATGGCGGCGC GGCGGCGACG GAGCACCGGC GGCGGCAGGG CGAGAGCATT AAATGAAAGC 
AAAAGAGTTA ATAATGGCAA CACGGCTCCA GAAGACTCTT CCCCTGCCAA GAAAACTCGT 
AGATGCCAGA GACAGGAGTC GAAAAAGATG CCTGTGGCTG GAGGAAAAGC TAATAAGGAC 
AGGACAGAAG ACAAGCAAGA TGAATCTGTG AAGGCCTTGC TGTTAAAGGG CAAAGCTCCT 
GTGGACCCAG AGTGTACAGC CAAGGTGGGG AAGGCTCATG TGTATTGTGA AGGAAATGAT 
GTCTATGATG TCATGCTAAA TCAGACCAAT CTCCAGTTCA ACAACAACAA GTACTATCTG 
ATTCAGCTAT TAGAAGATGA TGCCCAGAGG AACTTCAGTG TTTGGATGAG ATGGGGCCGA 
GTTGGGAAAA TGGGACAGCA CAGCCTGGTG GCTTGTTCAG GCAATCTCAA CAAGGCCAAG 
GAAATCTTTC AGAAGAAATT CCTTGACAAA ACGAAAAACA ATTGGGAAGA TCGAGAAAAG 
TTTGAGAAGG TGCCTGGAAA ATATGATATG CTACAGATGG ACTATGCCAC CAATACTCAG 
GATGAAGAGG AAACAAAGAA AGAGGAATCT CTTAAATCTC CCTTGAAGCC AGAGTCACAG 
CTAGATCTTC GGGTACAGGA GTTAATAAAG TTGATCTGTA ATGTTCAGGC CATGGAAGAA 
ATGATGATGG AAATGAAGTA TAATACCAAG AAAGCCCCAC TTGGGAAGCT GACAGTGGCA 
CAAATCAAGG CAGGTTACCA GTCTCTTAAG AAGATTGAGG ATTGTATTCG GGCTGGCCAG 
CATGGACGAG CTCTCATGGA AGCATGCAAT GAATTCTACA CCAGGATTCC GCATGACTTT 
GGACTCCGTA CTCCTCCACT AATCCGGACA CAGAAGGAAC TGTCAGAAAA AATACAATTA 
CTAGAGGCTT TGGGAGACAT TGAAATTGCT ATTAAGCTGG TGAAAACAGA GCTACAAAGC 
CCAGAACACC CATTGGACCA ACACTATAGA AACCTACATT GTGCCTTGCG CCCCCTTGAC 
CATGAAAGTT ATGAGTTCAA AGTGATTTCC CAGTACCTAC AATCTACCCA TGCTCCCACA 
CACAGCGACT ATACCATGAC CTTGCTGGAT TTGTTTGAAG TGGAGAAGGA TGGTGAGAAA 
GAAGCCTTCA GAGAGGACCT TCATAACAGG ATGCTTCTAT GGCATGGTTC CAGGATGAGT 
AACTGGGTGG GAATCTTGAG CCATGGGCTT CGAATTGCCC CACCTGAAGC TCCCATCACA 
GGTTACATGT TTGGGAAAGG AATCTACTTT GCTGACATGT CTTCCAAGAG TGCCAATTAC 
TGCTTTGCCT CTCGCCTAAA GAATACAGGA CTGCTGCTCT TATCAGAGGT AGCTCTAGGT 
CAGTGTAATG AACTACTAGA GGCCAATCCT AAGGCCGAAG GATTGCTTCA AGGTAAACAT 
AGCACCAAGG GGCTGGGCAA GATGGCTCCC AGTTCTGCCC ACTTCGTCAC CCTGAATGGG 
AGTACAGTGC CATTAGGACC AGCAAGTGAC ACAGGAATTC TGAATCCAGA TGGTTATACC 
CTCAACTACA ATGAATATAT TGTATATAAC CCCAACCAGG TCCGTATGCG GTACCTTTTA 
AAGGTTCAGT TTAATTTCCT TCAGCTGTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PARP2 ( XM_005267247.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005267304.1 Homo sapiens poly(ADP-ribose) polymerase 2 (PARP2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu47470
Clone ID Related Accession (Same CDS sequence)	XM_005267247.3
Accession Version	XM_005267247.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1503bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	poly [ADP-ribose] polymerase 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000014.9) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005267247.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGCGC GGCGGCGACG GAGCACCGGC GGCGGCAGGG CGAGAGCATT AAATGAAAGC 
AAAAGAGTTA ATAATGGCAA CACGGCTCCA GAAGACTCTT CCCCTGCCAA GAAAACTCGT 
AGATGCCAGA GACAGGAGTC GAAAAAGATG CCTGTGGCTG GAGGAAAAGC TAATAAGGAC 
AGGACAGAAG ACAAGCAAGA TGGTATGCCA GGAAGGTCAT GGGCCAGCAA AAGGGTCTCT 
GAATCTGTGA AGGCCTTGCT GTTAAAGGGC AAAGCTCCTG TGGACCCAGA GTGTACAGCC 
AAGGTGGGGA AGGCTCATGT GTATTGTGAA GGAAATGATG TCTATGATGT CATGCTAAAT 
CAGACCAATC TCCAGTTCAA CAACAACAAG TACTATCTGA TTCAGCTATT AGAAGATGAT 
GCCCAGAGGA ACTTCAGTGT TTGGATGAGA TGGGGCCGAG TTGGGAAAAT GGGACAGCAC 
AGCCTGGTGG CTTGTTCAGG CAATCTCAAC AAGGCCAAGG AAATCTTTCA GAAGAAATTC 
CTTGACAAAA CGAAAAACAA TTGGGAAGAT CGAGAAAAGT TTGAGAAGGT GCCTGGAAAA 
TATGATATGC TACAGATGGA CTATGCCACC AATACTCAGG ATGAAGAGGA AACAAAGAAA 
GAGGAATCTC TTAAATCTCC CTTGAAGCCA GAGTCACAGC TAGATCTTCG GGTACAGGAG 
TTAATAAAGT TGATCTGTAA TGTTCAGGCC ATGGAAGAAA TGATGATGGA AATGAAGTAT 
AATACCAAGA AAGCCCCACT TGGGAAGCTG ACAGTGGCAC AAATCAAGGC AGGTTACCAG 
TCTCTTAAGA AGATTGAGGA TTGTATTCGG GCTGGCCAGC ATGGACGAGC TCTCATGGAA 
GCATGCAATG AATTCTACAC CAGGATTCCG CATGACTTTG GACTCCGTAC TCCTCCACTA 
ATCCGGACAC AGAAGGAACT GTCAGAAAAA ATACAATTAC TAGAGGCTTT GGGAGACATT 
GAAATTGCTA TTAAGCTGGT GAAAACAGAG CTACAAAGCC CAGAACACCC ATTGGACCAA 
CACTATAGAA ACCTACATTG TGCCTTGCGC CCCCTTGACC ATGAAAGTTA TGAGTTCAAA 
GTGATTTCCC AGTACCTACA ATCTACCCAT GCTCCCACAC ACAGCGACTA TACCATGACC 
TTGCTGGATT TGTTTGAAGT GGAGAAGGAT GGTGAGAAAG AAGCCTTCAG AGAGGACCTT 
CATAACAGGA TGCTTCTATG GCATGGTTCC AGGATGAGTA ACTGGGTGGG AATCTTGAGC 
CATGGGCTTC GAATTGCCCC ACCTGAAGCT CCCATCACAG GTTACATGTT TGGGAAAGGA 
ATCTACTTTG CTGACATGTC TTCCAAGAGT GCCAATTACT GCTTTGCCTC TCGCCTAAAG 
AATACAGGAC TGCTGCTCTT ATCAGAGGAA TGGGAGTACA GTGCCATTAG GACCAGCAAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005267304.1
CDS	29..1531
Translation	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEEWEYSAIRTSK

Target ORF information:

RefSeq Version	XM_005267247.3
Organism	Homo sapiens(human)
Definition	Homo sapiens poly(ADP-ribose) polymerase 2 (PARP2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005267247.3

ORF Insert Sequence:

ATGGCGGCGC GGCGGCGACG GAGCACCGGC GGCGGCAGGG CGAGAGCATT AAATGAAAGC 
AAAAGAGTTA ATAATGGCAA CACGGCTCCA GAAGACTCTT CCCCTGCCAA GAAAACTCGT 
AGATGCCAGA GACAGGAGTC GAAAAAGATG CCTGTGGCTG GAGGAAAAGC TAATAAGGAC 
AGGACAGAAG ACAAGCAAGA TGGTATGCCA GGAAGGTCAT GGGCCAGCAA AAGGGTCTCT 
GAATCTGTGA AGGCCTTGCT GTTAAAGGGC AAAGCTCCTG TGGACCCAGA GTGTACAGCC 
AAGGTGGGGA AGGCTCATGT GTATTGTGAA GGAAATGATG TCTATGATGT CATGCTAAAT 
CAGACCAATC TCCAGTTCAA CAACAACAAG TACTATCTGA TTCAGCTATT AGAAGATGAT 
GCCCAGAGGA ACTTCAGTGT TTGGATGAGA TGGGGCCGAG TTGGGAAAAT GGGACAGCAC 
AGCCTGGTGG CTTGTTCAGG CAATCTCAAC AAGGCCAAGG AAATCTTTCA GAAGAAATTC 
CTTGACAAAA CGAAAAACAA TTGGGAAGAT CGAGAAAAGT TTGAGAAGGT GCCTGGAAAA 
TATGATATGC TACAGATGGA CTATGCCACC AATACTCAGG ATGAAGAGGA AACAAAGAAA 
GAGGAATCTC TTAAATCTCC CTTGAAGCCA GAGTCACAGC TAGATCTTCG GGTACAGGAG 
TTAATAAAGT TGATCTGTAA TGTTCAGGCC ATGGAAGAAA TGATGATGGA AATGAAGTAT 
AATACCAAGA AAGCCCCACT TGGGAAGCTG ACAGTGGCAC AAATCAAGGC AGGTTACCAG 
TCTCTTAAGA AGATTGAGGA TTGTATTCGG GCTGGCCAGC ATGGACGAGC TCTCATGGAA 
GCATGCAATG AATTCTACAC CAGGATTCCG CATGACTTTG GACTCCGTAC TCCTCCACTA 
ATCCGGACAC AGAAGGAACT GTCAGAAAAA ATACAATTAC TAGAGGCTTT GGGAGACATT 
GAAATTGCTA TTAAGCTGGT GAAAACAGAG CTACAAAGCC CAGAACACCC ATTGGACCAA 
CACTATAGAA ACCTACATTG TGCCTTGCGC CCCCTTGACC ATGAAAGTTA TGAGTTCAAA 
GTGATTTCCC AGTACCTACA ATCTACCCAT GCTCCCACAC ACAGCGACTA TACCATGACC 
TTGCTGGATT TGTTTGAAGT GGAGAAGGAT GGTGAGAAAG AAGCCTTCAG AGAGGACCTT 
CATAACAGGA TGCTTCTATG GCATGGTTCC AGGATGAGTA ACTGGGTGGG AATCTTGAGC 
CATGGGCTTC GAATTGCCCC ACCTGAAGCT CCCATCACAG GTTACATGTT TGGGAAAGGA 
ATCTACTTTG CTGACATGTC TTCCAAGAGT GCCAATTACT GCTTTGCCTC TCGCCTAAAG 
AATACAGGAC TGCTGCTCTT ATCAGAGGAA TGGGAGTACA GTGCCATTAG GACCAGCAAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PARP2 ( XM_017020912.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016876401.1 Homo sapiens poly(ADP-ribose) polymerase 2 (PARP2), transcript variant X2, mRNA.

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CloneID	OHu84724
Clone ID Related Accession (Same CDS sequence)	XM_017020912.1
Accession Version	XM_017020912.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1464bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	poly [ADP-ribose] polymerase 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000014.9) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGCGC GGCGGCGACG GAGCACCGGC GGCGGCAGGG CGAGAGCATT AAATGAAAGC 
AAAAGAGTTA ATAATGGCAA CACGGCTCCA GAAGACTCTT CCCCTGCCAA GAAAACTCGT 
AGATGCCAGA GACAGGAGTC GAAAAAGATG CCTGTGGCTG GAGGAAAAGC TAATAAGGAC 
AGGACAGAAG ACAAGCAAGA TGAATCTGTG AAGGCCTTGC TGTTAAAGGG CAAAGCTCCT 
GTGGACCCAG AGTGTACAGC CAAGGTGGGG AAGGCTCATG TGTATTGTGA AGGAAATGAT 
GTCTATGATG TCATGCTAAA TCAGACCAAT CTCCAGTTCA ACAACAACAA GTACTATCTG 
ATTCAGCTAT TAGAAGATGA TGCCCAGAGG AACTTCAGTG TTTGGATGAG ATGGGGCCGA 
GTTGGGAAAA TGGGACAGCA CAGCCTGGTG GCTTGTTCAG GCAATCTCAA CAAGGCCAAG 
GAAATCTTTC AGAAGAAATT CCTTGACAAA ACGAAAAACA ATTGGGAAGA TCGAGAAAAG 
TTTGAGAAGG TGCCTGGAAA ATATGATATG CTACAGATGG ACTATGCCAC CAATACTCAG 
GATGAAGAGG AAACAAAGAA AGAGGAATCT CTTAAATCTC CCTTGAAGCC AGAGTCACAG 
CTAGATCTTC GGGTACAGGA GTTAATAAAG TTGATCTGTA ATGTTCAGGC CATGGAAGAA 
ATGATGATGG AAATGAAGTA TAATACCAAG AAAGCCCCAC TTGGGAAGCT GACAGTGGCA 
CAAATCAAGG CAGGTTACCA GTCTCTTAAG AAGATTGAGG ATTGTATTCG GGCTGGCCAG 
CATGGACGAG CTCTCATGGA AGCATGCAAT GAATTCTACA CCAGGATTCC GCATGACTTT 
GGACTCCGTA CTCCTCCACT AATCCGGACA CAGAAGGAAC TGTCAGAAAA AATACAATTA 
CTAGAGGCTT TGGGAGACAT TGAAATTGCT ATTAAGCTGG TGAAAACAGA GCTACAAAGC 
CCAGAACACC CATTGGACCA ACACTATAGA AACCTACATT GTGCCTTGCG CCCCCTTGAC 
CATGAAAGTT ATGAGTTCAA AGTGATTTCC CAGTACCTAC AATCTACCCA TGCTCCCACA 
CACAGCGACT ATACCATGAC CTTGCTGGAT TTGTTTGAAG TGGAGAAGGA TGGTGAGAAA 
GAAGCCTTCA GAGAGGACCT TCATAACAGG ATGCTTCTAT GGCATGGTTC CAGGATGAGT 
AACTGGGTGG GAATCTTGAG CCATGGGCTT CGAATTGCCC CACCTGAAGC TCCCATCACA 
GGTTACATGT TTGGGAAAGG AATCTACTTT GCTGACATGT CTTCCAAGAG TGCCAATTAC 
TGCTTTGCCT CTCGCCTAAA GAATACAGGA CTGCTGCTCT TATCAGAGGA ATGGGAGTAC 
AGTGCCATTA GGACCAGCAA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016876401.1
CDS	602..2065
Translation	MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEEWEYSAIRTSK

Target ORF information:

RefSeq Version	XM_017020912.1
Organism	Homo sapiens(human)
Definition	Homo sapiens poly(ADP-ribose) polymerase 2 (PARP2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017020912.1

ORF Insert Sequence:

ATGGCGGCGC GGCGGCGACG GAGCACCGGC GGCGGCAGGG CGAGAGCATT AAATGAAAGC 
AAAAGAGTTA ATAATGGCAA CACGGCTCCA GAAGACTCTT CCCCTGCCAA GAAAACTCGT 
AGATGCCAGA GACAGGAGTC GAAAAAGATG CCTGTGGCTG GAGGAAAAGC TAATAAGGAC 
AGGACAGAAG ACAAGCAAGA TGAATCTGTG AAGGCCTTGC TGTTAAAGGG CAAAGCTCCT 
GTGGACCCAG AGTGTACAGC CAAGGTGGGG AAGGCTCATG TGTATTGTGA AGGAAATGAT 
GTCTATGATG TCATGCTAAA TCAGACCAAT CTCCAGTTCA ACAACAACAA GTACTATCTG 
ATTCAGCTAT TAGAAGATGA TGCCCAGAGG AACTTCAGTG TTTGGATGAG ATGGGGCCGA 
GTTGGGAAAA TGGGACAGCA CAGCCTGGTG GCTTGTTCAG GCAATCTCAA CAAGGCCAAG 
GAAATCTTTC AGAAGAAATT CCTTGACAAA ACGAAAAACA ATTGGGAAGA TCGAGAAAAG 
TTTGAGAAGG TGCCTGGAAA ATATGATATG CTACAGATGG ACTATGCCAC CAATACTCAG 
GATGAAGAGG AAACAAAGAA AGAGGAATCT CTTAAATCTC CCTTGAAGCC AGAGTCACAG 
CTAGATCTTC GGGTACAGGA GTTAATAAAG TTGATCTGTA ATGTTCAGGC CATGGAAGAA 
ATGATGATGG AAATGAAGTA TAATACCAAG AAAGCCCCAC TTGGGAAGCT GACAGTGGCA 
CAAATCAAGG CAGGTTACCA GTCTCTTAAG AAGATTGAGG ATTGTATTCG GGCTGGCCAG 
CATGGACGAG CTCTCATGGA AGCATGCAAT GAATTCTACA CCAGGATTCC GCATGACTTT 
GGACTCCGTA CTCCTCCACT AATCCGGACA CAGAAGGAAC TGTCAGAAAA AATACAATTA 
CTAGAGGCTT TGGGAGACAT TGAAATTGCT ATTAAGCTGG TGAAAACAGA GCTACAAAGC 
CCAGAACACC CATTGGACCA ACACTATAGA AACCTACATT GTGCCTTGCG CCCCCTTGAC 
CATGAAAGTT ATGAGTTCAA AGTGATTTCC CAGTACCTAC AATCTACCCA TGCTCCCACA 
CACAGCGACT ATACCATGAC CTTGCTGGAT TTGTTTGAAG TGGAGAAGGA TGGTGAGAAA 
GAAGCCTTCA GAGAGGACCT TCATAACAGG ATGCTTCTAT GGCATGGTTC CAGGATGAGT 
AACTGGGTGG GAATCTTGAG CCATGGGCTT CGAATTGCCC CACCTGAAGC TCCCATCACA 
GGTTACATGT TTGGGAAAGG AATCTACTTT GCTGACATGT CTTCCAAGAG TGCCAATTAC 
TGCTTTGCCT CTCGCCTAAA GAATACAGGA CTGCTGCTCT TATCAGAGGA ATGGGAGTAC 
AGTGCCATTA GGACCAGCAA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

PARP2 controls double-strand break repair pathway choice by limiting 53BP1 accumulation at DNA damage sites and promoting end-resection.
Nucleic acids research45(21)12325-12339(2017 Dec)
Fouquin A,Guirouilh-Barbat J,Lopez B,Hall J,Amor-Gu?ret M,Pennaneach V

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PARP2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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