CDH4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CDH4
Entrez Gene ID	1002
Full Name	cadherin 4
Synonyms	CAD4,R-CAD,RCAD
General protein information	Preferred Names cadherin 4 Names cadherin-4 R-cadherin cadherin 4, type 1, R-cadherin (retinal) cadherin 4, type 1, preproprotein retinal cadherin
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 20 Map Location: 20q13.33
Summary	This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].
Disorder MIM:	603006

mRNA and Protein(s)

mRNA	Protein	Name
NM_001252338.2	NP_001239267.1	cadherin-4 isoform 2
NM_001794.4	NP_001785.2	cadherin-4 isoform 1 preproprotein
NM_001794.5	NP_001785.2	cadherin-4 isoform 1 preproprotein
NM_001252339.3	NP_001239268.1	cadherin-4 isoform 3
NM_001252339.2	NP_001239268.1	cadherin-4 isoform 3

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	CDH4	XP_005635422.1
Pan troglodytes (chimpanzee)	CDH4	XP_001147328.2
Xenopus tropicalis (tropical clawed frog)	cdh4	NP_001116951.1
Homo sapiens (human)	CDH4	NP_001785.2
Bos taurus (cattle)	CDH4	XP_002692306.2
Gallus gallus (chicken)	CDH4	NP_001004391.1
Mus musculus (house mouse)	Cdh4	NP_033997.1
Rattus norvegicus (Norway rat)	Cdh4	XP_006235891.1
Danio rerio (zebrafish)	cdh4	NP_571161.2

Gene Ontology
Bibliography

Related articles in PubMed

Study on expression of CDH4 in lung cancer.
Li Z, Su D, Ying L, Yu G, Mao W
World journal of surgical oncology15(1)26(2017 Jan)

CDH4 suppresses the progression of salivary adenoid cystic carcinoma via E-cadherin co-expression.
Xie J, Feng Y, Lin T, Huang XY, Gan RH, Zhao Y, Su BH, Ding LC, She L, Chen J, Lin LS, Lin X, Zheng DL, Lu YG
Oncotarget7(50)82961-82971(2016 Dec)

Long non-coding RNA linc-cdh4-2 inhibits the migration and invasion of HCC cells by targeting R-cadherin pathway.
Gao Y, Wang G, Zhang C, Lin M, Liu X, Zeng Y, Liu J
Biochemical and biophysical research communications480(3)348-354(2016 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Low expression of CDH4 is associated with lung cancer.
Title: Study on expression of CDH4 in lung cancer.

Further knockdown R-cadherin in linc-cdh4-2 stably overexpressed cells, could significantly upregulate the protein levels of RAC1 and improve the cell migration and invasion abilities. Taken together, the novel linc-cdh4-2 may negatively regulate the motility of the HCC cells through targeting R-cadherin-RAC1 signaling pathway.
Title: Long non-coding RNA linc-cdh4-2 inhibits the migration and invasion of HCC cells by targeting R-cadherin pathway.

Data show that low expression of R-cadherin is associated with the poor prognosis in gastric cancer.
Title: Efficient isolation and proteomic analysis of cell plasma membrane proteins in gastric cancer reveal a novel differentiation and progression related cell surface marker, R-cadherin.

P-cadherin expression correlated with tumor progression and could be an independent predictor for bladder cancer survival.
Title: The prognostic value of P-cadherin in non-muscle-invasive bladder cancer.

R-cadherin adherens junction formation facilitates a mesenchymal to epithelial-like transition in MDA-MB-231 cells.
Title: Small GTPase Rho regulates R-cadherin through Dia1/profilin-1.

The following CDH4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CDH4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu25112	NM_001252338.2 Latest version!	Homo sapiens cadherin 4 (CDH4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OHu25138	NM_001794.5 Latest version!	Homo sapiens cadherin 4 (CDH4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
OHu25183	NM_001252339.3 Latest version!	Homo sapiens cadherin 4 (CDH4), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
View Old Accession Versions >>
OHu25138	NM_001794.4	Homo sapiens cadherin 4 (CDH4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
OHu25183	NM_001252339.2	Homo sapiens cadherin 4 (CDH4), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CDH4 ( NM_001252338.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001239267.1 Homo sapiens cadherin 4 (CDH4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu25112
Clone ID Related Accession (Same CDS sequence)	NM_001252338.2
Accession Version	NM_001252338.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2640bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Homo sapiens(human)
Product	cadherin-4 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK308345.1, AL162457.11, AL109911.47, KF511320.1 and AA213385.1. On Mar 27, 2014 this sequence version replaced NM_001252338.1. Transcript Variant: This variant (2) has an alternate exon in place of the first two exons compared to variant 1, and the alternate exon has an in-frame translation start site. The resulting isoform (2) has a shorter and distinct N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK308345.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACGGCA GCTGTGACTT CATTCTCAGC GCCTCCTTTC TACCCTGCTT TAAAGAAGTC 
AAGTTCAGCA GCTGTGTGGG GACCAAGGGG ACACAATATG AGACCAACAG CATGGACTTC 
AAAGTTGGGG CAGATGGGAC AGTCTTCGCC ACCCGGGAGC TGCAGGTCCC CTCCGAGCAG 
GTGGCGTTCA CGGTGACTGC ATGGGACAGC CAGACAGCAG AGAAATGGGA CGCCGTGGTG 
CGGTTGCTGG TGGCCCAGAC CTCGTCCCCG CACTCTGGAC ACAAGCCGCA GAAAGGAAAG 
AAGGTCGTGG CTCTGGACCC CTCTCCGCCT CCGAAGGACA CCCTGCTGCC GTGGCCCCAG 
CACCAGAACG CCAACGGGCT GAGGCGGCGC AAACGGGACT GGGTCATCCC GCCCATCAAC 
GTGCCCGAGA ACTCGCGCGG GCCCTTCCCG CAGCAGCTCG TGAGGATCCG GTCCGACAAA 
GACAATGACA TCCCCATCCG GTACAGCATC ACGGGAGTGG GCGCCGACCA GCCCCCCATG 
GAGGTCTTCA GCATTGACTC CATGTCCGGC CGGATGTACG TCACAAGGCC CATGGACCGG 
GAGGAGCACG CCTCTTACCA CCTCCGAGCC CACGCTGTGG ACATGAATGG CAACAAGGTG 
GAGAACCCCA TCGACCTGTA CATCTACGTC ATCGACATGA ATGACAACCG CCCTGAGTTC 
ATCAACCAGG TCTACAACGG CTCCGTGGAC GAGGGCTCCA AGCCAGGCAC CTACGTGATG 
ACCGTCACGG CCAACGATGC TGACGACAGC ACCACGGCCA ACGGGATGGT GCGGTACCGG 
ATCGTGACCC AGACCCCACA GAGCCCGTCC CAGAATATGT TCACCATCAA CAGCGAGACT 
GGAGATATCG TCACAGTGGC GGCTGGCCTG GACCGAGAGA AAGTTCAGCA GTACACAGTC 
ATCGTTCAGG CCACAGATAT GGAAGGAAAT CTCAACTATG GCCTCTCAAA CACAGCCACA 
GCCATCATCA CGGTGACAGA TGTGAATGAC AACCCGCCAG AATTTACCGC CAGCACGTTT 
GCAGGGGAGG TCCCCGAAAA CCGCGTGGAG ACCGTGGTCG CAAACCTCAC GGTGATGGAC 
CGAGATCAGC CCCACTCTCC AAACTGGAAT GCCGTTTACC GCATCATCAG TGGGGATCCA 
TCCGGGCACT TCAGCGTCCG CACAGACCCC GTAACCAACG AGGGCATGGT CACCGTGGTG 
AAGGCAGTCG ACTACGAGCT CAACAGAGCT TTCATGCTGA CAGTGATGGT GTCCAACCAG 
GCGCCCCTGG CCAGCGGAAT CCAGATGTCC TTCCAGTCCA CGGCAGGGGT GACCATCTCC 
ATCATGGACA TCAACGAGGC TCCCTACTTC CCCTCAAACC ACAAGCTGAT CCGCCTGGAG 
GAGGGCGTGC CCCCCGGCAC CGTGCTGACC ACGTTTTCAG CTGTGGACCC TGACCGGTTC 
ATGCAGCAGG CTGTGAGATA CTCAAAGCTG TCAGACCCAG CGAGCTGGCT GCACATCAAT 
GCCACCAACG GCCAGATCAC CACGGCGGCA GTGCTGGACC GTGAGTCCCT CTACACCAAA 
AACAACGTCT ACGAGGCCAC CTTCCTGGCA GCTGACAATG GGATACCCCC GGCCAGCGGC 
ACCGGGACCC TCCAGATCTA TCTCATTGAC ATCAACGACA ACGCCCCTGA GCTGCTGCCC 
AAGGAGGCGC AGATCTGCGA GAAGCCCAAC CTGAACGCCA TCAACATCAC GGCGGCCGAC 
GCTGACGTCG ACCCCAACAT CGGCCCCTAC GTCTTCGAGC TGCCCTTTGT CCCGGCGGCC 
GTGCGGAAGA ACTGGACCAT CACCCGCCTG AACGGTGACT ATGCCCAACT CAGCTTGCGC 
ATCCTGTACC TGGAGGCCGG GATGTATGAC GTCCCCATCA TCGTCACAGA CTCTGGAAAC 
CCTCCCCTGT CCAACACGTC CATCATCAAA GTCAAGGTGT GCCCATGTGA TGACAACGGG 
GACTGCACCA CCATTGGCGC AGTGGCAGCG GCTGGTCTGG GCACCGGTGC CATCGTGGCC 
ATCCTCATCT GCATCCTCAT CCTGCTGACC ATGGTCCTGC TGTTTGTCAT GTGGATGAAG 
CGGCGAGAGA AGGAGCGCCA CACGAAGCAG CTGCTCATTG ACCCCGAGGA CGACGTCCGC 
GACAACATCC TCAAGTATGA CGAGGAAGGC GGTGGCGAGG AGGACCAGGA CTACGACCTC 
AGCCAGCTGC AGCAGCCGGA AGCCATGGGG CACGTGCCAA GCAAAGCCCC TGGCGTGCGT 
CGCGTGGATG AGCGGCCGGT GGGCGCTGAG CCCCAGTACC CGATCAGGCC CATGGTGCCG 
CACCCAGGCG ACATCGGTGA CTTCATCAAT GAGGGACTCC GCGCTGCTGA CAACGACCCC 
ACGGCACCCC CCTATGACTC CCTGCTGGTC TTCGACTACG AGGGGAGCGG CTCCACCGCA 
GGCTCCGTCA GCTCCCTGAA CTCATCCAGT TCCGGGGACC AAGACTACGA TTACCTCAAC 
GACTGGGGGC CCAGATTCAA GAAGCTGGCG GACATGTATG GAGGTGGTGA AGAGGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001239267.1
CDS	15..2654
Translation	MNGSCDFILSASFLPCFKEVKFSSCVGTKGTQYETNSMDFKVGADGTVFATRELQVPSEQVAFTVTAWDSQTAEKWDAVVRLLVAQTSSPHSGHKPQKGKKVVALDPSPPPKDTLLPWPQHQNANGLRRRKRDWVIPPINVPENSRGPFPQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFSIDSMSGRMYVTRPMDREEHASYHLRAHAVDMNGNKVENPIDLYIYVIDMNDNRPEFINQVYNGSVDEGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVPENRVETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRAFMLTVMVSNQAPLASGIQMSFQSTAGVTISIMDINEAPYFPSNHKLIRLEEGVPPGTVLTTFSAVDPDRFMQQAVRYSKLSDPASWLHINATNGQITTAAVLDRESLYTKNNVYEATFLAADNGIPPASGTGTLQIYLIDINDNAPELLPKEAQICEKPNLNAINITAADADVDPNIGPYVFELPFVPAAVRKNWTITRLNGDYAQLSLRILYLEAGMYDVPIIVTDSGNPPLSNTSIIKVKVCPCDDNGDCTTIGAVAAAGLGTGAIVAILICILILLTMVLLFVMWMKRREKERHTKQLLIDPEDDVRDNILKYDEEGGGEEDQDYDLSQLQQPEAMGHVPSKAPGVRRVDERPVGAEPQYPIRPMVPHPGDIGDFINEGLRAADNDPTAPPYDSLLVFDYEGSGSTAGSVSSLNSSSSGDQDYDYLNDWGPRFKKLADMYGGGEED

Target ORF information:

RefSeq Version	NM_001252338.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cadherin 4 (CDH4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001252338.2

ORF Insert Sequence:

ATGAACGGCA GCTGTGACTT CATTCTCAGC GCCTCCTTTC TACCCTGCTT TAAAGAAGTC 
AAGTTCAGCA GCTGTGTGGG GACCAAGGGG ACACAATATG AGACCAACAG CATGGACTTC 
AAAGTTGGGG CAGATGGGAC AGTCTTCGCC ACCCGGGAGC TGCAGGTCCC CTCCGAGCAG 
GTGGCGTTCA CGGTGACTGC ATGGGACAGC CAGACAGCAG AGAAATGGGA CGCCGTGGTG 
CGGTTGCTGG TGGCCCAGAC CTCGTCCCCG CACTCTGGAC ACAAGCCGCA GAAAGGAAAG 
AAGGTCGTGG CTCTGGACCC CTCTCCGCCT CCGAAGGACA CCCTGCTGCC GTGGCCCCAG 
CACCAGAACG CCAACGGGCT GAGGCGGCGC AAACGGGACT GGGTCATCCC GCCCATCAAC 
GTGCCCGAGA ACTCGCGCGG GCCCTTCCCG CAGCAGCTCG TGAGGATCCG GTCCGACAAA 
GACAATGACA TCCCCATCCG GTACAGCATC ACGGGAGTGG GCGCCGACCA GCCCCCCATG 
GAGGTCTTCA GCATTGACTC CATGTCCGGC CGGATGTACG TCACAAGGCC CATGGACCGG 
GAGGAGCACG CCTCTTACCA CCTCCGAGCC CACGCTGTGG ACATGAATGG CAACAAGGTG 
GAGAACCCCA TCGACCTGTA CATCTACGTC ATCGACATGA ATGACAACCG CCCTGAGTTC 
ATCAACCAGG TCTACAACGG CTCCGTGGAC GAGGGCTCCA AGCCAGGCAC CTACGTGATG 
ACCGTCACGG CCAACGATGC TGACGACAGC ACCACGGCCA ACGGGATGGT GCGGTACCGG 
ATCGTGACCC AGACCCCACA GAGCCCGTCC CAGAATATGT TCACCATCAA CAGCGAGACT 
GGAGATATCG TCACAGTGGC GGCTGGCCTG GACCGAGAGA AAGTTCAGCA GTACACAGTC 
ATCGTTCAGG CCACAGATAT GGAAGGAAAT CTCAACTATG GCCTCTCAAA CACAGCCACA 
GCCATCATCA CGGTGACAGA TGTGAATGAC AACCCGCCAG AATTTACCGC CAGCACGTTT 
GCAGGGGAGG TCCCCGAAAA CCGCGTGGAG ACCGTGGTCG CAAACCTCAC GGTGATGGAC 
CGAGATCAGC CCCACTCTCC AAACTGGAAT GCCGTTTACC GCATCATCAG TGGGGATCCA 
TCCGGGCACT TCAGCGTCCG CACAGACCCC GTAACCAACG AGGGCATGGT CACCGTGGTG 
AAGGCAGTCG ACTACGAGCT CAACAGAGCT TTCATGCTGA CAGTGATGGT GTCCAACCAG 
GCGCCCCTGG CCAGCGGAAT CCAGATGTCC TTCCAGTCCA CGGCAGGGGT GACCATCTCC 
ATCATGGACA TCAACGAGGC TCCCTACTTC CCCTCAAACC ACAAGCTGAT CCGCCTGGAG 
GAGGGCGTGC CCCCCGGCAC CGTGCTGACC ACGTTTTCAG CTGTGGACCC TGACCGGTTC 
ATGCAGCAGG CTGTGAGATA CTCAAAGCTG TCAGACCCAG CGAGCTGGCT GCACATCAAT 
GCCACCAACG GCCAGATCAC CACGGCGGCA GTGCTGGACC GTGAGTCCCT CTACACCAAA 
AACAACGTCT ACGAGGCCAC CTTCCTGGCA GCTGACAATG GGATACCCCC GGCCAGCGGC 
ACCGGGACCC TCCAGATCTA TCTCATTGAC ATCAACGACA ACGCCCCTGA GCTGCTGCCC 
AAGGAGGCGC AGATCTGCGA GAAGCCCAAC CTGAACGCCA TCAACATCAC GGCGGCCGAC 
GCTGACGTCG ACCCCAACAT CGGCCCCTAC GTCTTCGAGC TGCCCTTTGT CCCGGCGGCC 
GTGCGGAAGA ACTGGACCAT CACCCGCCTG AACGGTGACT ATGCCCAACT CAGCTTGCGC 
ATCCTGTACC TGGAGGCCGG GATGTATGAC GTCCCCATCA TCGTCACAGA CTCTGGAAAC 
CCTCCCCTGT CCAACACGTC CATCATCAAA GTCAAGGTGT GCCCATGTGA TGACAACGGG 
GACTGCACCA CCATTGGCGC AGTGGCAGCG GCTGGTCTGG GCACCGGTGC CATCGTGGCC 
ATCCTCATCT GCATCCTCAT CCTGCTGACC ATGGTCCTGC TGTTTGTCAT GTGGATGAAG 
CGGCGAGAGA AGGAGCGCCA CACGAAGCAG CTGCTCATTG ACCCCGAGGA CGACGTCCGC 
GACAACATCC TCAAGTATGA CGAGGAAGGC GGTGGCGAGG AGGACCAGGA CTACGACCTC 
AGCCAGCTGC AGCAGCCGGA AGCCATGGGG CACGTGCCAA GCAAAGCCCC TGGCGTGCGT 
CGCGTGGATG AGCGGCCGGT GGGCGCTGAG CCCCAGTACC CGATCAGGCC CATGGTGCCG 
CACCCAGGCG ACATCGGTGA CTTCATCAAT GAGGGACTCC GCGCTGCTGA CAACGACCCC 
ACGGCACCCC CCTATGACTC CCTGCTGGTC TTCGACTACG AGGGGAGCGG CTCCACCGCA 
GGCTCCGTCA GCTCCCTGAA CTCATCCAGT TCCGGGGACC AAGACTACGA TTACCTCAAC 
GACTGGGGGC CCAGATTCAA GAAGCTGGCG GACATGTATG GAGGTGGTGA AGAGGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDH4 ( NM_001794.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001785.2 Homo sapiens cadherin 4 (CDH4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu25138
Clone ID Related Accession (Same CDS sequence)	NM_001794.4 , NM_001794.5
Accession Version	NM_001794.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2751bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	cadherin-4 isoform 1 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC101651.1, AL109911.47, KF511320.1 and AA213385.1. On Mar 27, 2014 this sequence version replaced NM_001794.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC101651.1, L34059.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145313, SAMEA2146236 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACCGCGG GCGCCGGCGT GCTCCTTCTG CTGCTCTCGC TCTCCGGCGC GCTCCGGGCC 
CATAATGAGG ATCTTACAAC TAGAGAGACC TGCAAGGCTG GGTTCTCTGA AGATGATTAC 
ACGGCATTAA TCTCCCAAAA TATTCTAGAA GGGGAAAAGC TACTTCAAGT CAAGTTCAGC 
AGCTGTGTGG GGACCAAGGG GACACAATAT GAGACCAACA GCATGGACTT CAAAGTTGGG 
GCAGATGGGA CAGTCTTCGC CACCCGGGAG CTGCAGGTCC CCTCCGAGCA GGTGGCGTTC 
ACGGTGACTG CATGGGACAG CCAGACAGCA GAGAAATGGG ACGCCGTGGT GCGGTTGCTG 
GTGGCCCAGA CCTCGTCCCC GCACTCTGGA CACAAGCCGC AGAAAGGAAA GAAGGTCGTG 
GCTCTGGACC CCTCTCCGCC TCCGAAGGAC ACCCTGCTGC CGTGGCCCCA GCACCAGAAC 
GCCAACGGGC TGAGGCGGCG CAAACGGGAC TGGGTCATCC CGCCCATCAA CGTGCCCGAG 
AACTCGCGCG GGCCCTTCCC GCAGCAGCTC GTGAGGATCC GGTCCGACAA AGACAATGAC 
ATCCCCATCC GGTACAGCAT CACGGGAGTG GGCGCCGACC AGCCCCCCAT GGAGGTCTTC 
AGCATTGACT CCATGTCCGG CCGGATGTAC GTCACAAGGC CCATGGACCG GGAGGAGCAC 
GCCTCTTACC ACCTCCGAGC CCACGCTGTG GACATGAATG GCAACAAGGT GGAGAACCCC 
ATCGACCTGT ACATCTACGT CATCGACATG AATGACAACC GCCCTGAGTT CATCAACCAG 
GTCTACAACG GCTCCGTGGA CGAGGGCTCC AAGCCAGGCA CCTACGTGAT GACCGTCACG 
GCCAACGATG CTGACGACAG CACCACGGCC AACGGGATGG TGCGGTACCG GATCGTGACC 
CAGACCCCAC AGAGCCCGTC CCAGAATATG TTCACCATCA ACAGCGAGAC TGGAGATATC 
GTCACAGTGG CGGCTGGCCT GGACCGAGAG AAAGTTCAGC AGTACACAGT CATCGTTCAG 
GCCACAGATA TGGAAGGAAA TCTCAACTAT GGCCTCTCAA ACACAGCCAC AGCCATCATC 
ACGGTGACAG ATGTGAATGA CAACCCGCCA GAATTTACCG CCAGCACGTT TGCAGGGGAG 
GTCCCCGAAA ACCGCGTGGA GACCGTGGTC GCAAACCTCA CGGTGATGGA CCGAGATCAG 
CCCCACTCTC CAAACTGGAA TGCCGTTTAC CGCATCATCA GTGGGGATCC ATCCGGGCAC 
TTCAGCGTCC GCACAGACCC CGTAACCAAC GAGGGCATGG TCACCGTGGT GAAGGCAGTC 
GACTACGAGC TCAACAGAGC TTTCATGCTG ACAGTGATGG TGTCCAACCA GGCGCCCCTG 
GCCAGCGGAA TCCAGATGTC CTTCCAGTCC ACGGCAGGGG TGACCATCTC CATCATGGAC 
ATCAACGAGG CTCCCTACTT CCCCTCAAAC CACAAGCTGA TCCGCCTGGA GGAGGGCGTG 
CCCCCCGGCA CCGTGCTGAC CACGTTTTCA GCTGTGGACC CTGACCGGTT CATGCAGCAG 
GCTGTGAGAT ACTCAAAGCT GTCAGACCCA GCGAGCTGGC TGCACATCAA TGCCACCAAC 
GGCCAGATCA CCACGGCGGC AGTGCTGGAC CGTGAGTCCC TCTACACCAA AAACAACGTC 
TACGAGGCCA CCTTCCTGGC AGCTGACAAT GGGATACCCC CGGCCAGCGG CACCGGGACC 
CTCCAGATCT ATCTCATTGA CATCAACGAC AACGCCCCTG AGCTGCTGCC CAAGGAGGCG 
CAGATCTGCG AGAAGCCCAA CCTGAACGCC ATCAACATCA CGGCGGCCGA CGCTGACGTC 
GACCCCAACA TCGGCCCCTA CGTCTTCGAG CTGCCCTTTG TCCCGGCGGC CGTGCGGAAG 
AACTGGACCA TCACCCGCCT GAACGGTGAC TATGCCCAAC TCAGCTTGCG CATCCTGTAC 
CTGGAGGCCG GGATGTATGA CGTCCCCATC ATCGTCACAG ACTCTGGAAA CCCTCCCCTG 
TCCAACACGT CCATCATCAA AGTCAAGGTG TGCCCATGTG ATGACAACGG GGACTGCACC 
ACCATTGGCG CAGTGGCAGC GGCTGGTCTG GGCACCGGTG CCATCGTGGC CATCCTCATC 
TGCATCCTCA TCCTGCTGAC CATGGTCCTG CTGTTTGTCA TGTGGATGAA GCGGCGAGAG 
AAGGAGCGCC ACACGAAGCA GCTGCTCATT GACCCCGAGG ACGACGTCCG CGACAACATC 
CTCAAGTATG ACGAGGAAGG CGGTGGCGAG GAGGACCAGG ACTACGACCT CAGCCAGCTG 
CAGCAGCCGG AAGCCATGGG GCACGTGCCA AGCAAAGCCC CTGGCGTGCG TCGCGTGGAT 
GAGCGGCCGG TGGGCGCTGA GCCCCAGTAC CCGATCAGGC CCATGGTGCC GCACCCAGGC 
GACATCGGTG ACTTCATCAA TGAGGGACTC CGCGCTGCTG ACAACGACCC CACGGCACCC 
CCCTATGACT CCCTGCTGGT CTTCGACTAC GAGGGGAGCG GCTCCACCGC AGGCTCCGTC 
AGCTCCCTGA ACTCATCCAG TTCCGGGGAC CAAGACTACG ATTACCTCAA CGACTGGGGG 
CCCAGATTCA AGAAGCTGGC GGACATGTAT GGAGGTGGTG AAGAGGATTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001785.2
CDS	89..2839
Translation	MTAGAGVLLLLLSLSGALRAHNEDLTTRETCKAGFSEDDYTALISQNILEGEKLLQVKFSSCVGTKGTQYETNSMDFKVGADGTVFATRELQVPSEQVAFTVTAWDSQTAEKWDAVVRLLVAQTSSPHSGHKPQKGKKVVALDPSPPPKDTLLPWPQHQNANGLRRRKRDWVIPPINVPENSRGPFPQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFSIDSMSGRMYVTRPMDREEHASYHLRAHAVDMNGNKVENPIDLYIYVIDMNDNRPEFINQVYNGSVDEGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVPENRVETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRAFMLTVMVSNQAPLASGIQMSFQSTAGVTISIMDINEAPYFPSNHKLIRLEEGVPPGTVLTTFSAVDPDRFMQQAVRYSKLSDPASWLHINATNGQITTAAVLDRESLYTKNNVYEATFLAADNGIPPASGTGTLQIYLIDINDNAPELLPKEAQICEKPNLNAINITAADADVDPNIGPYVFELPFVPAAVRKNWTITRLNGDYAQLSLRILYLEAGMYDVPIIVTDSGNPPLSNTSIIKVKVCPCDDNGDCTTIGAVAAAGLGTGAIVAILICILILLTMVLLFVMWMKRREKERHTKQLLIDPEDDVRDNILKYDEEGGGEEDQDYDLSQLQQPEAMGHVPSKAPGVRRVDERPVGAEPQYPIRPMVPHPGDIGDFINEGLRAADNDPTAPPYDSLLVFDYEGSGSTAGSVSSLNSSSSGDQDYDYLNDWGPRFKKLADMYGGGEED

Target ORF information:

RefSeq Version	NM_001794.4
Organism	Homo sapiens(human)
Definition	Homo sapiens cadherin 4 (CDH4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001794.4

ORF Insert Sequence:

ATGACCGCGG GCGCCGGCGT GCTCCTTCTG CTGCTCTCGC TCTCCGGCGC GCTCCGGGCC 
CATAATGAGG ATCTTACAAC TAGAGAGACC TGCAAGGCTG GGTTCTCTGA AGATGATTAC 
ACGGCATTAA TCTCCCAAAA TATTCTAGAA GGGGAAAAGC TACTTCAAGT CAAGTTCAGC 
AGCTGTGTGG GGACCAAGGG GACACAATAT GAGACCAACA GCATGGACTT CAAAGTTGGG 
GCAGATGGGA CAGTCTTCGC CACCCGGGAG CTGCAGGTCC CCTCCGAGCA GGTGGCGTTC 
ACGGTGACTG CATGGGACAG CCAGACAGCA GAGAAATGGG ACGCCGTGGT GCGGTTGCTG 
GTGGCCCAGA CCTCGTCCCC GCACTCTGGA CACAAGCCGC AGAAAGGAAA GAAGGTCGTG 
GCTCTGGACC CCTCTCCGCC TCCGAAGGAC ACCCTGCTGC CGTGGCCCCA GCACCAGAAC 
GCCAACGGGC TGAGGCGGCG CAAACGGGAC TGGGTCATCC CGCCCATCAA CGTGCCCGAG 
AACTCGCGCG GGCCCTTCCC GCAGCAGCTC GTGAGGATCC GGTCCGACAA AGACAATGAC 
ATCCCCATCC GGTACAGCAT CACGGGAGTG GGCGCCGACC AGCCCCCCAT GGAGGTCTTC 
AGCATTGACT CCATGTCCGG CCGGATGTAC GTCACAAGGC CCATGGACCG GGAGGAGCAC 
GCCTCTTACC ACCTCCGAGC CCACGCTGTG GACATGAATG GCAACAAGGT GGAGAACCCC 
ATCGACCTGT ACATCTACGT CATCGACATG AATGACAACC GCCCTGAGTT CATCAACCAG 
GTCTACAACG GCTCCGTGGA CGAGGGCTCC AAGCCAGGCA CCTACGTGAT GACCGTCACG 
GCCAACGATG CTGACGACAG CACCACGGCC AACGGGATGG TGCGGTACCG GATCGTGACC 
CAGACCCCAC AGAGCCCGTC CCAGAATATG TTCACCATCA ACAGCGAGAC TGGAGATATC 
GTCACAGTGG CGGCTGGCCT GGACCGAGAG AAAGTTCAGC AGTACACAGT CATCGTTCAG 
GCCACAGATA TGGAAGGAAA TCTCAACTAT GGCCTCTCAA ACACAGCCAC AGCCATCATC 
ACGGTGACAG ATGTGAATGA CAACCCGCCA GAATTTACCG CCAGCACGTT TGCAGGGGAG 
GTCCCCGAAA ACCGCGTGGA GACCGTGGTC GCAAACCTCA CGGTGATGGA CCGAGATCAG 
CCCCACTCTC CAAACTGGAA TGCCGTTTAC CGCATCATCA GTGGGGATCC ATCCGGGCAC 
TTCAGCGTCC GCACAGACCC CGTAACCAAC GAGGGCATGG TCACCGTGGT GAAGGCAGTC 
GACTACGAGC TCAACAGAGC TTTCATGCTG ACAGTGATGG TGTCCAACCA GGCGCCCCTG 
GCCAGCGGAA TCCAGATGTC CTTCCAGTCC ACGGCAGGGG TGACCATCTC CATCATGGAC 
ATCAACGAGG CTCCCTACTT CCCCTCAAAC CACAAGCTGA TCCGCCTGGA GGAGGGCGTG 
CCCCCCGGCA CCGTGCTGAC CACGTTTTCA GCTGTGGACC CTGACCGGTT CATGCAGCAG 
GCTGTGAGAT ACTCAAAGCT GTCAGACCCA GCGAGCTGGC TGCACATCAA TGCCACCAAC 
GGCCAGATCA CCACGGCGGC AGTGCTGGAC CGTGAGTCCC TCTACACCAA AAACAACGTC 
TACGAGGCCA CCTTCCTGGC AGCTGACAAT GGGATACCCC CGGCCAGCGG CACCGGGACC 
CTCCAGATCT ATCTCATTGA CATCAACGAC AACGCCCCTG AGCTGCTGCC CAAGGAGGCG 
CAGATCTGCG AGAAGCCCAA CCTGAACGCC ATCAACATCA CGGCGGCCGA CGCTGACGTC 
GACCCCAACA TCGGCCCCTA CGTCTTCGAG CTGCCCTTTG TCCCGGCGGC CGTGCGGAAG 
AACTGGACCA TCACCCGCCT GAACGGTGAC TATGCCCAAC TCAGCTTGCG CATCCTGTAC 
CTGGAGGCCG GGATGTATGA CGTCCCCATC ATCGTCACAG ACTCTGGAAA CCCTCCCCTG 
TCCAACACGT CCATCATCAA AGTCAAGGTG TGCCCATGTG ATGACAACGG GGACTGCACC 
ACCATTGGCG CAGTGGCAGC GGCTGGTCTG GGCACCGGTG CCATCGTGGC CATCCTCATC 
TGCATCCTCA TCCTGCTGAC CATGGTCCTG CTGTTTGTCA TGTGGATGAA GCGGCGAGAG 
AAGGAGCGCC ACACGAAGCA GCTGCTCATT GACCCCGAGG ACGACGTCCG CGACAACATC 
CTCAAGTATG ACGAGGAAGG CGGTGGCGAG GAGGACCAGG ACTACGACCT CAGCCAGCTG 
CAGCAGCCGG AAGCCATGGG GCACGTGCCA AGCAAAGCCC CTGGCGTGCG TCGCGTGGAT 
GAGCGGCCGG TGGGCGCTGA GCCCCAGTAC CCGATCAGGC CCATGGTGCC GCACCCAGGC 
GACATCGGTG ACTTCATCAA TGAGGGACTC CGCGCTGCTG ACAACGACCC CACGGCACCC 
CCCTATGACT CCCTGCTGGT CTTCGACTAC GAGGGGAGCG GCTCCACCGC AGGCTCCGTC 
AGCTCCCTGA ACTCATCCAG TTCCGGGGAC CAAGACTACG ATTACCTCAA CGACTGGGGG 
CCCAGATTCA AGAAGCTGGC GGACATGTAT GGAGGTGGTG AAGAGGATTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDH4 ( NM_001794.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_001785.2 Homo sapiens cadherin 4 (CDH4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu25138
Clone ID Related Accession (Same CDS sequence)	NM_001794.4 , NM_001794.5
Accession Version	NM_001794.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2751bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	cadherin-4 isoform 1 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL365229.13, BC101651.1, AL109911.47, KF511320.1 and AA213385.1. On Nov 23, 2018 this sequence version replaced NM_001794.4. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: L34059.1, BC101651.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145313, SAMEA2146236 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000614565.5/ ENSP00000484928.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGACCGCGG GCGCCGGCGT GCTCCTTCTG CTGCTCTCGC TCTCCGGCGC GCTCCGGGCC 
CATAATGAGG ATCTTACAAC TAGAGAGACC TGCAAGGCTG GGTTCTCTGA AGATGATTAC 
ACGGCATTAA TCTCCCAAAA TATTCTAGAA GGGGAAAAGC TACTTCAAGT CAAGTTCAGC 
AGCTGTGTGG GGACCAAGGG GACACAATAT GAGACCAACA GCATGGACTT CAAAGTTGGG 
GCAGATGGGA CAGTCTTCGC CACCCGGGAG CTGCAGGTCC CCTCCGAGCA GGTGGCGTTC 
ACGGTGACTG CATGGGACAG CCAGACAGCA GAGAAATGGG ACGCCGTGGT GCGGTTGCTG 
GTGGCCCAGA CCTCGTCCCC GCACTCTGGA CACAAGCCGC AGAAAGGAAA GAAGGTCGTG 
GCTCTGGACC CCTCTCCGCC TCCGAAGGAC ACCCTGCTGC CGTGGCCCCA GCACCAGAAC 
GCCAACGGGC TGAGGCGGCG CAAACGGGAC TGGGTCATCC CGCCCATCAA CGTGCCCGAG 
AACTCGCGCG GGCCCTTCCC GCAGCAGCTC GTGAGGATCC GGTCCGACAA AGACAATGAC 
ATCCCCATCC GGTACAGCAT CACGGGAGTG GGCGCCGACC AGCCCCCCAT GGAGGTCTTC 
AGCATTGACT CCATGTCCGG CCGGATGTAC GTCACAAGGC CCATGGACCG GGAGGAGCAC 
GCCTCTTACC ACCTCCGAGC CCACGCTGTG GACATGAATG GCAACAAGGT GGAGAACCCC 
ATCGACCTGT ACATCTACGT CATCGACATG AATGACAACC GCCCTGAGTT CATCAACCAG 
GTCTACAACG GCTCCGTGGA CGAGGGCTCC AAGCCAGGCA CCTACGTGAT GACCGTCACG 
GCCAACGATG CTGACGACAG CACCACGGCC AACGGGATGG TGCGGTACCG GATCGTGACC 
CAGACCCCAC AGAGCCCGTC CCAGAATATG TTCACCATCA ACAGCGAGAC TGGAGATATC 
GTCACAGTGG CGGCTGGCCT GGACCGAGAG AAAGTTCAGC AGTACACAGT CATCGTTCAG 
GCCACAGATA TGGAAGGAAA TCTCAACTAT GGCCTCTCAA ACACAGCCAC AGCCATCATC 
ACGGTGACAG ATGTGAATGA CAACCCGCCA GAATTTACCG CCAGCACGTT TGCAGGGGAG 
GTCCCCGAAA ACCGCGTGGA GACCGTGGTC GCAAACCTCA CGGTGATGGA CCGAGATCAG 
CCCCACTCTC CAAACTGGAA TGCCGTTTAC CGCATCATCA GTGGGGATCC ATCCGGGCAC 
TTCAGCGTCC GCACAGACCC CGTAACCAAC GAGGGCATGG TCACCGTGGT GAAGGCAGTC 
GACTACGAGC TCAACAGAGC TTTCATGCTG ACAGTGATGG TGTCCAACCA GGCGCCCCTG 
GCCAGCGGAA TCCAGATGTC CTTCCAGTCC ACGGCAGGGG TGACCATCTC CATCATGGAC 
ATCAACGAGG CTCCCTACTT CCCCTCAAAC CACAAGCTGA TCCGCCTGGA GGAGGGCGTG 
CCCCCCGGCA CCGTGCTGAC CACGTTTTCA GCTGTGGACC CTGACCGGTT CATGCAGCAG 
GCTGTGAGAT ACTCAAAGCT GTCAGACCCA GCGAGCTGGC TGCACATCAA TGCCACCAAC 
GGCCAGATCA CCACGGCGGC AGTGCTGGAC CGTGAGTCCC TCTACACCAA AAACAACGTC 
TACGAGGCCA CCTTCCTGGC AGCTGACAAT GGGATACCCC CGGCCAGCGG CACCGGGACC 
CTCCAGATCT ATCTCATTGA CATCAACGAC AACGCCCCTG AGCTGCTGCC CAAGGAGGCG 
CAGATCTGCG AGAAGCCCAA CCTGAACGCC ATCAACATCA CGGCGGCCGA CGCTGACGTC 
GACCCCAACA TCGGCCCCTA CGTCTTCGAG CTGCCCTTTG TCCCGGCGGC CGTGCGGAAG 
AACTGGACCA TCACCCGCCT GAACGGTGAC TATGCCCAAC TCAGCTTGCG CATCCTGTAC 
CTGGAGGCCG GGATGTATGA CGTCCCCATC ATCGTCACAG ACTCTGGAAA CCCTCCCCTG 
TCCAACACGT CCATCATCAA AGTCAAGGTG TGCCCATGTG ATGACAACGG GGACTGCACC 
ACCATTGGCG CAGTGGCAGC GGCTGGTCTG GGCACCGGTG CCATCGTGGC CATCCTCATC 
TGCATCCTCA TCCTGCTGAC CATGGTCCTG CTGTTTGTCA TGTGGATGAA GCGGCGAGAG 
AAGGAGCGCC ACACGAAGCA GCTGCTCATT GACCCCGAGG ACGACGTCCG CGACAACATC 
CTCAAGTATG ACGAGGAAGG CGGTGGCGAG GAGGACCAGG ACTACGACCT CAGCCAGCTG 
CAGCAGCCGG AAGCCATGGG GCACGTGCCA AGCAAAGCCC CTGGCGTGCG TCGCGTGGAT 
GAGCGGCCGG TGGGCGCTGA GCCCCAGTAC CCGATCAGGC CCATGGTGCC GCACCCAGGC 
GACATCGGTG ACTTCATCAA TGAGGGACTC CGCGCTGCTG ACAACGACCC CACGGCACCC 
CCCTATGACT CCCTGCTGGT CTTCGACTAC GAGGGGAGCG GCTCCACCGC AGGCTCCGTC 
AGCTCCCTGA ACTCATCCAG TTCCGGGGAC CAAGACTACG ATTACCTCAA CGACTGGGGG 
CCCAGATTCA AGAAGCTGGC GGACATGTAT GGAGGTGGTG AAGAGGATTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001785.2
CDS	254..3004
Translation	MTAGAGVLLLLLSLSGALRAHNEDLTTRETCKAGFSEDDYTALISQNILEGEKLLQVKFSSCVGTKGTQYETNSMDFKVGADGTVFATRELQVPSEQVAFTVTAWDSQTAEKWDAVVRLLVAQTSSPHSGHKPQKGKKVVALDPSPPPKDTLLPWPQHQNANGLRRRKRDWVIPPINVPENSRGPFPQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFSIDSMSGRMYVTRPMDREEHASYHLRAHAVDMNGNKVENPIDLYIYVIDMNDNRPEFINQVYNGSVDEGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVPENRVETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRAFMLTVMVSNQAPLASGIQMSFQSTAGVTISIMDINEAPYFPSNHKLIRLEEGVPPGTVLTTFSAVDPDRFMQQAVRYSKLSDPASWLHINATNGQITTAAVLDRESLYTKNNVYEATFLAADNGIPPASGTGTLQIYLIDINDNAPELLPKEAQICEKPNLNAINITAADADVDPNIGPYVFELPFVPAAVRKNWTITRLNGDYAQLSLRILYLEAGMYDVPIIVTDSGNPPLSNTSIIKVKVCPCDDNGDCTTIGAVAAAGLGTGAIVAILICILILLTMVLLFVMWMKRREKERHTKQLLIDPEDDVRDNILKYDEEGGGEEDQDYDLSQLQQPEAMGHVPSKAPGVRRVDERPVGAEPQYPIRPMVPHPGDIGDFINEGLRAADNDPTAPPYDSLLVFDYEGSGSTAGSVSSLNSSSSGDQDYDYLNDWGPRFKKLADMYGGGEED

Target ORF information:

RefSeq Version	NM_001794.5
Organism	Homo sapiens(human)
Definition	Homo sapiens cadherin 4 (CDH4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001794.5

ORF Insert Sequence:

ATGACCGCGG GCGCCGGCGT GCTCCTTCTG CTGCTCTCGC TCTCCGGCGC GCTCCGGGCC 
CATAATGAGG ATCTTACAAC TAGAGAGACC TGCAAGGCTG GGTTCTCTGA AGATGATTAC 
ACGGCATTAA TCTCCCAAAA TATTCTAGAA GGGGAAAAGC TACTTCAAGT CAAGTTCAGC 
AGCTGTGTGG GGACCAAGGG GACACAATAT GAGACCAACA GCATGGACTT CAAAGTTGGG 
GCAGATGGGA CAGTCTTCGC CACCCGGGAG CTGCAGGTCC CCTCCGAGCA GGTGGCGTTC 
ACGGTGACTG CATGGGACAG CCAGACAGCA GAGAAATGGG ACGCCGTGGT GCGGTTGCTG 
GTGGCCCAGA CCTCGTCCCC GCACTCTGGA CACAAGCCGC AGAAAGGAAA GAAGGTCGTG 
GCTCTGGACC CCTCTCCGCC TCCGAAGGAC ACCCTGCTGC CGTGGCCCCA GCACCAGAAC 
GCCAACGGGC TGAGGCGGCG CAAACGGGAC TGGGTCATCC CGCCCATCAA CGTGCCCGAG 
AACTCGCGCG GGCCCTTCCC GCAGCAGCTC GTGAGGATCC GGTCCGACAA AGACAATGAC 
ATCCCCATCC GGTACAGCAT CACGGGAGTG GGCGCCGACC AGCCCCCCAT GGAGGTCTTC 
AGCATTGACT CCATGTCCGG CCGGATGTAC GTCACAAGGC CCATGGACCG GGAGGAGCAC 
GCCTCTTACC ACCTCCGAGC CCACGCTGTG GACATGAATG GCAACAAGGT GGAGAACCCC 
ATCGACCTGT ACATCTACGT CATCGACATG AATGACAACC GCCCTGAGTT CATCAACCAG 
GTCTACAACG GCTCCGTGGA CGAGGGCTCC AAGCCAGGCA CCTACGTGAT GACCGTCACG 
GCCAACGATG CTGACGACAG CACCACGGCC AACGGGATGG TGCGGTACCG GATCGTGACC 
CAGACCCCAC AGAGCCCGTC CCAGAATATG TTCACCATCA ACAGCGAGAC TGGAGATATC 
GTCACAGTGG CGGCTGGCCT GGACCGAGAG AAAGTTCAGC AGTACACAGT CATCGTTCAG 
GCCACAGATA TGGAAGGAAA TCTCAACTAT GGCCTCTCAA ACACAGCCAC AGCCATCATC 
ACGGTGACAG ATGTGAATGA CAACCCGCCA GAATTTACCG CCAGCACGTT TGCAGGGGAG 
GTCCCCGAAA ACCGCGTGGA GACCGTGGTC GCAAACCTCA CGGTGATGGA CCGAGATCAG 
CCCCACTCTC CAAACTGGAA TGCCGTTTAC CGCATCATCA GTGGGGATCC ATCCGGGCAC 
TTCAGCGTCC GCACAGACCC CGTAACCAAC GAGGGCATGG TCACCGTGGT GAAGGCAGTC 
GACTACGAGC TCAACAGAGC TTTCATGCTG ACAGTGATGG TGTCCAACCA GGCGCCCCTG 
GCCAGCGGAA TCCAGATGTC CTTCCAGTCC ACGGCAGGGG TGACCATCTC CATCATGGAC 
ATCAACGAGG CTCCCTACTT CCCCTCAAAC CACAAGCTGA TCCGCCTGGA GGAGGGCGTG 
CCCCCCGGCA CCGTGCTGAC CACGTTTTCA GCTGTGGACC CTGACCGGTT CATGCAGCAG 
GCTGTGAGAT ACTCAAAGCT GTCAGACCCA GCGAGCTGGC TGCACATCAA TGCCACCAAC 
GGCCAGATCA CCACGGCGGC AGTGCTGGAC CGTGAGTCCC TCTACACCAA AAACAACGTC 
TACGAGGCCA CCTTCCTGGC AGCTGACAAT GGGATACCCC CGGCCAGCGG CACCGGGACC 
CTCCAGATCT ATCTCATTGA CATCAACGAC AACGCCCCTG AGCTGCTGCC CAAGGAGGCG 
CAGATCTGCG AGAAGCCCAA CCTGAACGCC ATCAACATCA CGGCGGCCGA CGCTGACGTC 
GACCCCAACA TCGGCCCCTA CGTCTTCGAG CTGCCCTTTG TCCCGGCGGC CGTGCGGAAG 
AACTGGACCA TCACCCGCCT GAACGGTGAC TATGCCCAAC TCAGCTTGCG CATCCTGTAC 
CTGGAGGCCG GGATGTATGA CGTCCCCATC ATCGTCACAG ACTCTGGAAA CCCTCCCCTG 
TCCAACACGT CCATCATCAA AGTCAAGGTG TGCCCATGTG ATGACAACGG GGACTGCACC 
ACCATTGGCG CAGTGGCAGC GGCTGGTCTG GGCACCGGTG CCATCGTGGC CATCCTCATC 
TGCATCCTCA TCCTGCTGAC CATGGTCCTG CTGTTTGTCA TGTGGATGAA GCGGCGAGAG 
AAGGAGCGCC ACACGAAGCA GCTGCTCATT GACCCCGAGG ACGACGTCCG CGACAACATC 
CTCAAGTATG ACGAGGAAGG CGGTGGCGAG GAGGACCAGG ACTACGACCT CAGCCAGCTG 
CAGCAGCCGG AAGCCATGGG GCACGTGCCA AGCAAAGCCC CTGGCGTGCG TCGCGTGGAT 
GAGCGGCCGG TGGGCGCTGA GCCCCAGTAC CCGATCAGGC CCATGGTGCC GCACCCAGGC 
GACATCGGTG ACTTCATCAA TGAGGGACTC CGCGCTGCTG ACAACGACCC CACGGCACCC 
CCCTATGACT CCCTGCTGGT CTTCGACTAC GAGGGGAGCG GCTCCACCGC AGGCTCCGTC 
AGCTCCCTGA ACTCATCCAG TTCCGGGGAC CAAGACTACG ATTACCTCAA CGACTGGGGG 
CCCAGATTCA AGAAGCTGGC GGACATGTAT GGAGGTGGTG AAGAGGATTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDH4 ( NM_001252339.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001239268.1 Homo sapiens cadherin 4 (CDH4), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu25183
Clone ID Related Accession (Same CDS sequence)	NM_001252339.3 , NM_001252339.2
Accession Version	NM_001252339.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2529bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-31
Organism	Homo sapiens(human)
Product	cadherin-4 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC330816.1, AK124724.1, AL162457.11, AL109911.47, KF511320.1 and AA213385.1. On May 31, 2019 this sequence version replaced NM_001252339.2. Transcript Variant: This variant (3) has an alternate exon in place of the first two exons compared to variant 1, but the alternate exon does not have an in-frame translation start site. The resulting isoform (3) is shorter at the N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK124724.1, SRR1803614.25516.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03465404 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACTTCA AAGTTGGGGC AGATGGGACA GTCTTCGCCA CCCGGGAGCT GCAGGTCCCC 
TCCGAGCAGG TGGCGTTCAC GGTGACTGCA TGGGACAGCC AGACAGCAGA GAAATGGGAC 
GCCGTGGTGC GGTTGCTGGT GGCCCAGACC TCGTCCCCGC ACTCTGGACA CAAGCCGCAG 
AAAGGAAAGA AGGTCGTGGC TCTGGACCCC TCTCCGCCTC CGAAGGACAC CCTGCTGCCG 
TGGCCCCAGC ACCAGAACGC CAACGGGCTG AGGCGGCGCA AACGGGACTG GGTCATCCCG 
CCCATCAACG TGCCCGAGAA CTCGCGCGGG CCCTTCCCGC AGCAGCTCGT GAGGATCCGG 
TCCGACAAAG ACAATGACAT CCCCATCCGG TACAGCATCA CGGGAGTGGG CGCCGACCAG 
CCCCCCATGG AGGTCTTCAG CATTGACTCC ATGTCCGGCC GGATGTACGT CACAAGGCCC 
ATGGACCGGG AGGAGCACGC CTCTTACCAC CTCCGAGCCC ACGCTGTGGA CATGAATGGC 
AACAAGGTGG AGAACCCCAT CGACCTGTAC ATCTACGTCA TCGACATGAA TGACAACCGC 
CCTGAGTTCA TCAACCAGGT CTACAACGGC TCCGTGGACG AGGGCTCCAA GCCAGGCACC 
TACGTGATGA CCGTCACGGC CAACGATGCT GACGACAGCA CCACGGCCAA CGGGATGGTG 
CGGTACCGGA TCGTGACCCA GACCCCACAG AGCCCGTCCC AGAATATGTT CACCATCAAC 
AGCGAGACTG GAGATATCGT CACAGTGGCG GCTGGCCTGG ACCGAGAGAA AGTTCAGCAG 
TACACAGTCA TCGTTCAGGC CACAGATATG GAAGGAAATC TCAACTATGG CCTCTCAAAC 
ACAGCCACAG CCATCATCAC GGTGACAGAT GTGAATGACA ACCCGCCAGA ATTTACCGCC 
AGCACGTTTG CAGGGGAGGT CCCCGAAAAC CGCGTGGAGA CCGTGGTCGC AAACCTCACG 
GTGATGGACC GAGATCAGCC CCACTCTCCA AACTGGAATG CCGTTTACCG CATCATCAGT 
GGGGATCCAT CCGGGCACTT CAGCGTCCGC ACAGACCCCG TAACCAACGA GGGCATGGTC 
ACCGTGGTGA AGGCAGTCGA CTACGAGCTC AACAGAGCTT TCATGCTGAC AGTGATGGTG 
TCCAACCAGG CGCCCCTGGC CAGCGGAATC CAGATGTCCT TCCAGTCCAC GGCAGGGGTG 
ACCATCTCCA TCATGGACAT CAACGAGGCT CCCTACTTCC CCTCAAACCA CAAGCTGATC 
CGCCTGGAGG AGGGCGTGCC CCCCGGCACC GTGCTGACCA CGTTTTCAGC TGTGGACCCT 
GACCGGTTCA TGCAGCAGGC TGTGAGATAC TCAAAGCTGT CAGACCCAGC GAGCTGGCTG 
CACATCAATG CCACCAACGG CCAGATCACC ACGGCGGCAG TGCTGGACCG TGAGTCCCTC 
TACACCAAAA ACAACGTCTA CGAGGCCACC TTCCTGGCAG CTGACAATGG GATACCCCCG 
GCCAGCGGCA CCGGGACCCT CCAGATCTAT CTCATTGACA TCAACGACAA CGCCCCTGAG 
CTGCTGCCCA AGGAGGCGCA GATCTGCGAG AAGCCCAACC TGAACGCCAT CAACATCACG 
GCGGCCGACG CTGACGTCGA CCCCAACATC GGCCCCTACG TCTTCGAGCT GCCCTTTGTC 
CCGGCGGCCG TGCGGAAGAA CTGGACCATC ACCCGCCTGA ACGGTGACTA TGCCCAACTC 
AGCTTGCGCA TCCTGTACCT GGAGGCCGGG ATGTATGACG TCCCCATCAT CGTCACAGAC 
TCTGGAAACC CTCCCCTGTC CAACACGTCC ATCATCAAAG TCAAGGTGTG CCCATGTGAT 
GACAACGGGG ACTGCACCAC CATTGGCGCA GTGGCAGCGG CTGGTCTGGG CACCGGTGCC 
ATCGTGGCCA TCCTCATCTG CATCCTCATC CTGCTGACCA TGGTCCTGCT GTTTGTCATG 
TGGATGAAGC GGCGAGAGAA GGAGCGCCAC ACGAAGCAGC TGCTCATTGA CCCCGAGGAC 
GACGTCCGCG ACAACATCCT CAAGTATGAC GAGGAAGGCG GTGGCGAGGA GGACCAGGAC 
TACGACCTCA GCCAGCTGCA GCAGCCGGAA GCCATGGGGC ACGTGCCAAG CAAAGCCCCT 
GGCGTGCGTC GCGTGGATGA GCGGCCGGTG GGCGCTGAGC CCCAGTACCC GATCAGGCCC 
ATGGTGCCGC ACCCAGGCGA CATCGGTGAC TTCATCAATG AGGGACTCCG CGCTGCTGAC 
AACGACCCCA CGGCACCCCC CTATGACTCC CTGCTGGTCT TCGACTACGA GGGGAGCGGC 
TCCACCGCAG GCTCCGTCAG CTCCCTGAAC TCATCCAGTT CCGGGGACCA AGACTACGAT 
TACCTCAACG ACTGGGGGCC CAGATTCAAG AAGCTGGCGG ACATGTATGG AGGTGGTGAA 
GAGGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001239268.1
CDS	283..2811
Translation	MDFKVGADGTVFATRELQVPSEQVAFTVTAWDSQTAEKWDAVVRLLVAQTSSPHSGHKPQKGKKVVALDPSPPPKDTLLPWPQHQNANGLRRRKRDWVIPPINVPENSRGPFPQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFSIDSMSGRMYVTRPMDREEHASYHLRAHAVDMNGNKVENPIDLYIYVIDMNDNRPEFINQVYNGSVDEGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVPENRVETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRAFMLTVMVSNQAPLASGIQMSFQSTAGVTISIMDINEAPYFPSNHKLIRLEEGVPPGTVLTTFSAVDPDRFMQQAVRYSKLSDPASWLHINATNGQITTAAVLDRESLYTKNNVYEATFLAADNGIPPASGTGTLQIYLIDINDNAPELLPKEAQICEKPNLNAINITAADADVDPNIGPYVFELPFVPAAVRKNWTITRLNGDYAQLSLRILYLEAGMYDVPIIVTDSGNPPLSNTSIIKVKVCPCDDNGDCTTIGAVAAAGLGTGAIVAILICILILLTMVLLFVMWMKRREKERHTKQLLIDPEDDVRDNILKYDEEGGGEEDQDYDLSQLQQPEAMGHVPSKAPGVRRVDERPVGAEPQYPIRPMVPHPGDIGDFINEGLRAADNDPTAPPYDSLLVFDYEGSGSTAGSVSSLNSSSSGDQDYDYLNDWGPRFKKLADMYGGGEED

Target ORF information:

RefSeq Version	NM_001252339.3
Organism	Homo sapiens(human)
Definition	Homo sapiens cadherin 4 (CDH4), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001252339.3

ORF Insert Sequence:

ATGGACTTCA AAGTTGGGGC AGATGGGACA GTCTTCGCCA CCCGGGAGCT GCAGGTCCCC 
TCCGAGCAGG TGGCGTTCAC GGTGACTGCA TGGGACAGCC AGACAGCAGA GAAATGGGAC 
GCCGTGGTGC GGTTGCTGGT GGCCCAGACC TCGTCCCCGC ACTCTGGACA CAAGCCGCAG 
AAAGGAAAGA AGGTCGTGGC TCTGGACCCC TCTCCGCCTC CGAAGGACAC CCTGCTGCCG 
TGGCCCCAGC ACCAGAACGC CAACGGGCTG AGGCGGCGCA AACGGGACTG GGTCATCCCG 
CCCATCAACG TGCCCGAGAA CTCGCGCGGG CCCTTCCCGC AGCAGCTCGT GAGGATCCGG 
TCCGACAAAG ACAATGACAT CCCCATCCGG TACAGCATCA CGGGAGTGGG CGCCGACCAG 
CCCCCCATGG AGGTCTTCAG CATTGACTCC ATGTCCGGCC GGATGTACGT CACAAGGCCC 
ATGGACCGGG AGGAGCACGC CTCTTACCAC CTCCGAGCCC ACGCTGTGGA CATGAATGGC 
AACAAGGTGG AGAACCCCAT CGACCTGTAC ATCTACGTCA TCGACATGAA TGACAACCGC 
CCTGAGTTCA TCAACCAGGT CTACAACGGC TCCGTGGACG AGGGCTCCAA GCCAGGCACC 
TACGTGATGA CCGTCACGGC CAACGATGCT GACGACAGCA CCACGGCCAA CGGGATGGTG 
CGGTACCGGA TCGTGACCCA GACCCCACAG AGCCCGTCCC AGAATATGTT CACCATCAAC 
AGCGAGACTG GAGATATCGT CACAGTGGCG GCTGGCCTGG ACCGAGAGAA AGTTCAGCAG 
TACACAGTCA TCGTTCAGGC CACAGATATG GAAGGAAATC TCAACTATGG CCTCTCAAAC 
ACAGCCACAG CCATCATCAC GGTGACAGAT GTGAATGACA ACCCGCCAGA ATTTACCGCC 
AGCACGTTTG CAGGGGAGGT CCCCGAAAAC CGCGTGGAGA CCGTGGTCGC AAACCTCACG 
GTGATGGACC GAGATCAGCC CCACTCTCCA AACTGGAATG CCGTTTACCG CATCATCAGT 
GGGGATCCAT CCGGGCACTT CAGCGTCCGC ACAGACCCCG TAACCAACGA GGGCATGGTC 
ACCGTGGTGA AGGCAGTCGA CTACGAGCTC AACAGAGCTT TCATGCTGAC AGTGATGGTG 
TCCAACCAGG CGCCCCTGGC CAGCGGAATC CAGATGTCCT TCCAGTCCAC GGCAGGGGTG 
ACCATCTCCA TCATGGACAT CAACGAGGCT CCCTACTTCC CCTCAAACCA CAAGCTGATC 
CGCCTGGAGG AGGGCGTGCC CCCCGGCACC GTGCTGACCA CGTTTTCAGC TGTGGACCCT 
GACCGGTTCA TGCAGCAGGC TGTGAGATAC TCAAAGCTGT CAGACCCAGC GAGCTGGCTG 
CACATCAATG CCACCAACGG CCAGATCACC ACGGCGGCAG TGCTGGACCG TGAGTCCCTC 
TACACCAAAA ACAACGTCTA CGAGGCCACC TTCCTGGCAG CTGACAATGG GATACCCCCG 
GCCAGCGGCA CCGGGACCCT CCAGATCTAT CTCATTGACA TCAACGACAA CGCCCCTGAG 
CTGCTGCCCA AGGAGGCGCA GATCTGCGAG AAGCCCAACC TGAACGCCAT CAACATCACG 
GCGGCCGACG CTGACGTCGA CCCCAACATC GGCCCCTACG TCTTCGAGCT GCCCTTTGTC 
CCGGCGGCCG TGCGGAAGAA CTGGACCATC ACCCGCCTGA ACGGTGACTA TGCCCAACTC 
AGCTTGCGCA TCCTGTACCT GGAGGCCGGG ATGTATGACG TCCCCATCAT CGTCACAGAC 
TCTGGAAACC CTCCCCTGTC CAACACGTCC ATCATCAAAG TCAAGGTGTG CCCATGTGAT 
GACAACGGGG ACTGCACCAC CATTGGCGCA GTGGCAGCGG CTGGTCTGGG CACCGGTGCC 
ATCGTGGCCA TCCTCATCTG CATCCTCATC CTGCTGACCA TGGTCCTGCT GTTTGTCATG 
TGGATGAAGC GGCGAGAGAA GGAGCGCCAC ACGAAGCAGC TGCTCATTGA CCCCGAGGAC 
GACGTCCGCG ACAACATCCT CAAGTATGAC GAGGAAGGCG GTGGCGAGGA GGACCAGGAC 
TACGACCTCA GCCAGCTGCA GCAGCCGGAA GCCATGGGGC ACGTGCCAAG CAAAGCCCCT 
GGCGTGCGTC GCGTGGATGA GCGGCCGGTG GGCGCTGAGC CCCAGTACCC GATCAGGCCC 
ATGGTGCCGC ACCCAGGCGA CATCGGTGAC TTCATCAATG AGGGACTCCG CGCTGCTGAC 
AACGACCCCA CGGCACCCCC CTATGACTCC CTGCTGGTCT TCGACTACGA GGGGAGCGGC 
TCCACCGCAG GCTCCGTCAG CTCCCTGAAC TCATCCAGTT CCGGGGACCA AGACTACGAT 
TACCTCAACG ACTGGGGGCC CAGATTCAAG AAGCTGGCGG ACATGTATGG AGGTGGTGAA 
GAGGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDH4 ( NM_001252339.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001239268.1 Homo sapiens cadherin 4 (CDH4), transcript variant 3, mRNA.

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CloneID	OHu25183
Clone ID Related Accession (Same CDS sequence)	NM_001252339.3 , NM_001252339.2
Accession Version	NM_001252339.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2529bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	cadherin-4 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC330816.1, AK124724.1, AL162457.11, AL109911.47, KF511320.1 and AA213385.1. On Mar 27, 2014 this sequence version replaced NM_001252339.1. Transcript Variant: This variant (3) has an alternate exon in place of the first two exons compared to variant 1, but the alternate exon does not have an in-frame translation start site. The resulting isoform (3) is shorter at the N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK124724.1, SRR1803613.285452.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03465404 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACTTCA AAGTTGGGGC AGATGGGACA GTCTTCGCCA CCCGGGAGCT GCAGGTCCCC 
TCCGAGCAGG TGGCGTTCAC GGTGACTGCA TGGGACAGCC AGACAGCAGA GAAATGGGAC 
GCCGTGGTGC GGTTGCTGGT GGCCCAGACC TCGTCCCCGC ACTCTGGACA CAAGCCGCAG 
AAAGGAAAGA AGGTCGTGGC TCTGGACCCC TCTCCGCCTC CGAAGGACAC CCTGCTGCCG 
TGGCCCCAGC ACCAGAACGC CAACGGGCTG AGGCGGCGCA AACGGGACTG GGTCATCCCG 
CCCATCAACG TGCCCGAGAA CTCGCGCGGG CCCTTCCCGC AGCAGCTCGT GAGGATCCGG 
TCCGACAAAG ACAATGACAT CCCCATCCGG TACAGCATCA CGGGAGTGGG CGCCGACCAG 
CCCCCCATGG AGGTCTTCAG CATTGACTCC ATGTCCGGCC GGATGTACGT CACAAGGCCC 
ATGGACCGGG AGGAGCACGC CTCTTACCAC CTCCGAGCCC ACGCTGTGGA CATGAATGGC 
AACAAGGTGG AGAACCCCAT CGACCTGTAC ATCTACGTCA TCGACATGAA TGACAACCGC 
CCTGAGTTCA TCAACCAGGT CTACAACGGC TCCGTGGACG AGGGCTCCAA GCCAGGCACC 
TACGTGATGA CCGTCACGGC CAACGATGCT GACGACAGCA CCACGGCCAA CGGGATGGTG 
CGGTACCGGA TCGTGACCCA GACCCCACAG AGCCCGTCCC AGAATATGTT CACCATCAAC 
AGCGAGACTG GAGATATCGT CACAGTGGCG GCTGGCCTGG ACCGAGAGAA AGTTCAGCAG 
TACACAGTCA TCGTTCAGGC CACAGATATG GAAGGAAATC TCAACTATGG CCTCTCAAAC 
ACAGCCACAG CCATCATCAC GGTGACAGAT GTGAATGACA ACCCGCCAGA ATTTACCGCC 
AGCACGTTTG CAGGGGAGGT CCCCGAAAAC CGCGTGGAGA CCGTGGTCGC AAACCTCACG 
GTGATGGACC GAGATCAGCC CCACTCTCCA AACTGGAATG CCGTTTACCG CATCATCAGT 
GGGGATCCAT CCGGGCACTT CAGCGTCCGC ACAGACCCCG TAACCAACGA GGGCATGGTC 
ACCGTGGTGA AGGCAGTCGA CTACGAGCTC AACAGAGCTT TCATGCTGAC AGTGATGGTG 
TCCAACCAGG CGCCCCTGGC CAGCGGAATC CAGATGTCCT TCCAGTCCAC GGCAGGGGTG 
ACCATCTCCA TCATGGACAT CAACGAGGCT CCCTACTTCC CCTCAAACCA CAAGCTGATC 
CGCCTGGAGG AGGGCGTGCC CCCCGGCACC GTGCTGACCA CGTTTTCAGC TGTGGACCCT 
GACCGGTTCA TGCAGCAGGC TGTGAGATAC TCAAAGCTGT CAGACCCAGC GAGCTGGCTG 
CACATCAATG CCACCAACGG CCAGATCACC ACGGCGGCAG TGCTGGACCG TGAGTCCCTC 
TACACCAAAA ACAACGTCTA CGAGGCCACC TTCCTGGCAG CTGACAATGG GATACCCCCG 
GCCAGCGGCA CCGGGACCCT CCAGATCTAT CTCATTGACA TCAACGACAA CGCCCCTGAG 
CTGCTGCCCA AGGAGGCGCA GATCTGCGAG AAGCCCAACC TGAACGCCAT CAACATCACG 
GCGGCCGACG CTGACGTCGA CCCCAACATC GGCCCCTACG TCTTCGAGCT GCCCTTTGTC 
CCGGCGGCCG TGCGGAAGAA CTGGACCATC ACCCGCCTGA ACGGTGACTA TGCCCAACTC 
AGCTTGCGCA TCCTGTACCT GGAGGCCGGG ATGTATGACG TCCCCATCAT CGTCACAGAC 
TCTGGAAACC CTCCCCTGTC CAACACGTCC ATCATCAAAG TCAAGGTGTG CCCATGTGAT 
GACAACGGGG ACTGCACCAC CATTGGCGCA GTGGCAGCGG CTGGTCTGGG CACCGGTGCC 
ATCGTGGCCA TCCTCATCTG CATCCTCATC CTGCTGACCA TGGTCCTGCT GTTTGTCATG 
TGGATGAAGC GGCGAGAGAA GGAGCGCCAC ACGAAGCAGC TGCTCATTGA CCCCGAGGAC 
GACGTCCGCG ACAACATCCT CAAGTATGAC GAGGAAGGCG GTGGCGAGGA GGACCAGGAC 
TACGACCTCA GCCAGCTGCA GCAGCCGGAA GCCATGGGGC ACGTGCCAAG CAAAGCCCCT 
GGCGTGCGTC GCGTGGATGA GCGGCCGGTG GGCGCTGAGC CCCAGTACCC GATCAGGCCC 
ATGGTGCCGC ACCCAGGCGA CATCGGTGAC TTCATCAATG AGGGACTCCG CGCTGCTGAC 
AACGACCCCA CGGCACCCCC CTATGACTCC CTGCTGGTCT TCGACTACGA GGGGAGCGGC 
TCCACCGCAG GCTCCGTCAG CTCCCTGAAC TCATCCAGTT CCGGGGACCA AGACTACGAT 
TACCTCAACG ACTGGGGGCC CAGATTCAAG AAGCTGGCGG ACATGTATGG AGGTGGTGAA 
GAGGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001239268.1
CDS	283..2811
Translation	MDFKVGADGTVFATRELQVPSEQVAFTVTAWDSQTAEKWDAVVRLLVAQTSSPHSGHKPQKGKKVVALDPSPPPKDTLLPWPQHQNANGLRRRKRDWVIPPINVPENSRGPFPQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFSIDSMSGRMYVTRPMDREEHASYHLRAHAVDMNGNKVENPIDLYIYVIDMNDNRPEFINQVYNGSVDEGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVPENRVETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRAFMLTVMVSNQAPLASGIQMSFQSTAGVTISIMDINEAPYFPSNHKLIRLEEGVPPGTVLTTFSAVDPDRFMQQAVRYSKLSDPASWLHINATNGQITTAAVLDRESLYTKNNVYEATFLAADNGIPPASGTGTLQIYLIDINDNAPELLPKEAQICEKPNLNAINITAADADVDPNIGPYVFELPFVPAAVRKNWTITRLNGDYAQLSLRILYLEAGMYDVPIIVTDSGNPPLSNTSIIKVKVCPCDDNGDCTTIGAVAAAGLGTGAIVAILICILILLTMVLLFVMWMKRREKERHTKQLLIDPEDDVRDNILKYDEEGGGEEDQDYDLSQLQQPEAMGHVPSKAPGVRRVDERPVGAEPQYPIRPMVPHPGDIGDFINEGLRAADNDPTAPPYDSLLVFDYEGSGSTAGSVSSLNSSSSGDQDYDYLNDWGPRFKKLADMYGGGEED

Target ORF information:

RefSeq Version	NM_001252339.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cadherin 4 (CDH4), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001252339.2

ORF Insert Sequence:

ATGGACTTCA AAGTTGGGGC AGATGGGACA GTCTTCGCCA CCCGGGAGCT GCAGGTCCCC 
TCCGAGCAGG TGGCGTTCAC GGTGACTGCA TGGGACAGCC AGACAGCAGA GAAATGGGAC 
GCCGTGGTGC GGTTGCTGGT GGCCCAGACC TCGTCCCCGC ACTCTGGACA CAAGCCGCAG 
AAAGGAAAGA AGGTCGTGGC TCTGGACCCC TCTCCGCCTC CGAAGGACAC CCTGCTGCCG 
TGGCCCCAGC ACCAGAACGC CAACGGGCTG AGGCGGCGCA AACGGGACTG GGTCATCCCG 
CCCATCAACG TGCCCGAGAA CTCGCGCGGG CCCTTCCCGC AGCAGCTCGT GAGGATCCGG 
TCCGACAAAG ACAATGACAT CCCCATCCGG TACAGCATCA CGGGAGTGGG CGCCGACCAG 
CCCCCCATGG AGGTCTTCAG CATTGACTCC ATGTCCGGCC GGATGTACGT CACAAGGCCC 
ATGGACCGGG AGGAGCACGC CTCTTACCAC CTCCGAGCCC ACGCTGTGGA CATGAATGGC 
AACAAGGTGG AGAACCCCAT CGACCTGTAC ATCTACGTCA TCGACATGAA TGACAACCGC 
CCTGAGTTCA TCAACCAGGT CTACAACGGC TCCGTGGACG AGGGCTCCAA GCCAGGCACC 
TACGTGATGA CCGTCACGGC CAACGATGCT GACGACAGCA CCACGGCCAA CGGGATGGTG 
CGGTACCGGA TCGTGACCCA GACCCCACAG AGCCCGTCCC AGAATATGTT CACCATCAAC 
AGCGAGACTG GAGATATCGT CACAGTGGCG GCTGGCCTGG ACCGAGAGAA AGTTCAGCAG 
TACACAGTCA TCGTTCAGGC CACAGATATG GAAGGAAATC TCAACTATGG CCTCTCAAAC 
ACAGCCACAG CCATCATCAC GGTGACAGAT GTGAATGACA ACCCGCCAGA ATTTACCGCC 
AGCACGTTTG CAGGGGAGGT CCCCGAAAAC CGCGTGGAGA CCGTGGTCGC AAACCTCACG 
GTGATGGACC GAGATCAGCC CCACTCTCCA AACTGGAATG CCGTTTACCG CATCATCAGT 
GGGGATCCAT CCGGGCACTT CAGCGTCCGC ACAGACCCCG TAACCAACGA GGGCATGGTC 
ACCGTGGTGA AGGCAGTCGA CTACGAGCTC AACAGAGCTT TCATGCTGAC AGTGATGGTG 
TCCAACCAGG CGCCCCTGGC CAGCGGAATC CAGATGTCCT TCCAGTCCAC GGCAGGGGTG 
ACCATCTCCA TCATGGACAT CAACGAGGCT CCCTACTTCC CCTCAAACCA CAAGCTGATC 
CGCCTGGAGG AGGGCGTGCC CCCCGGCACC GTGCTGACCA CGTTTTCAGC TGTGGACCCT 
GACCGGTTCA TGCAGCAGGC TGTGAGATAC TCAAAGCTGT CAGACCCAGC GAGCTGGCTG 
CACATCAATG CCACCAACGG CCAGATCACC ACGGCGGCAG TGCTGGACCG TGAGTCCCTC 
TACACCAAAA ACAACGTCTA CGAGGCCACC TTCCTGGCAG CTGACAATGG GATACCCCCG 
GCCAGCGGCA CCGGGACCCT CCAGATCTAT CTCATTGACA TCAACGACAA CGCCCCTGAG 
CTGCTGCCCA AGGAGGCGCA GATCTGCGAG AAGCCCAACC TGAACGCCAT CAACATCACG 
GCGGCCGACG CTGACGTCGA CCCCAACATC GGCCCCTACG TCTTCGAGCT GCCCTTTGTC 
CCGGCGGCCG TGCGGAAGAA CTGGACCATC ACCCGCCTGA ACGGTGACTA TGCCCAACTC 
AGCTTGCGCA TCCTGTACCT GGAGGCCGGG ATGTATGACG TCCCCATCAT CGTCACAGAC 
TCTGGAAACC CTCCCCTGTC CAACACGTCC ATCATCAAAG TCAAGGTGTG CCCATGTGAT 
GACAACGGGG ACTGCACCAC CATTGGCGCA GTGGCAGCGG CTGGTCTGGG CACCGGTGCC 
ATCGTGGCCA TCCTCATCTG CATCCTCATC CTGCTGACCA TGGTCCTGCT GTTTGTCATG 
TGGATGAAGC GGCGAGAGAA GGAGCGCCAC ACGAAGCAGC TGCTCATTGA CCCCGAGGAC 
GACGTCCGCG ACAACATCCT CAAGTATGAC GAGGAAGGCG GTGGCGAGGA GGACCAGGAC 
TACGACCTCA GCCAGCTGCA GCAGCCGGAA GCCATGGGGC ACGTGCCAAG CAAAGCCCCT 
GGCGTGCGTC GCGTGGATGA GCGGCCGGTG GGCGCTGAGC CCCAGTACCC GATCAGGCCC 
ATGGTGCCGC ACCCAGGCGA CATCGGTGAC TTCATCAATG AGGGACTCCG CGCTGCTGAC 
AACGACCCCA CGGCACCCCC CTATGACTCC CTGCTGGTCT TCGACTACGA GGGGAGCGGC 
TCCACCGCAG GCTCCGTCAG CTCCCTGAAC TCATCCAGTT CCGGGGACCA AGACTACGAT 
TACCTCAACG ACTGGGGGCC CAGATTCAAG AAGCTGGCGG ACATGTATGG AGGTGGTGAA 
GAGGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Study on expression of CDH4 in lung cancer.
World journal of surgical oncology15(1)26(2017 Jan)
Li Z,Su D,Ying L,Yu G,Mao W

CDH4 suppresses the progression of salivary adenoid cystic carcinoma via E-cadherin co-expression.
Oncotarget7(50)82961-82971(2016 Dec)
Xie J,Feng Y,Lin T,Huang XY,Gan RH,Zhao Y,Su BH,Ding LC,She L,Chen J,Lin LS,Lin X,Zheng DL,Lu YG

Long non-coding RNA linc-cdh4-2 inhibits the migration and invasion of HCC cells by targeting R-cadherin pathway.
Biochemical and biophysical research communications480(3)348-354(2016 Nov)
Gao Y,Wang G,Zhang C,Lin M,Liu X,Zeng Y,Liu J

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CDH4 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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