PDCD6 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PDCD6
Entrez Gene ID	10016
Full Name	programmed cell death 6
Synonyms	ALG-2,ALG2,PEF1B
General protein information	Preferred Names programmed cell death 6 Names programmed cell death protein 6 apoptosis-linked gene 2 protein apoptosis-linked gene 2 protein homolog probable calcium-binding protein ALG-2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 5 Map Location: 5p15.33
Summary	This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5. [provided by RefSeq, May 2012].
Disorder MIM:	601057

mRNA and Protein(s)

mRNA	Protein	Name
NM_001267557.1	NP_001254486.1	programmed cell death protein 6 isoform 3
NM_001267556.1	NP_001254485.1	programmed cell death protein 6 isoform 2
NM_001267559.2	NP_001254488.1	programmed cell death protein 6 isoform 5
NM_013232.3	NP_037364.1	programmed cell death protein 6 isoform 1
NM_001267559.1	NP_001254488.1	programmed cell death protein 6 isoform 5
NM_001267556.2	NP_001254485.1	programmed cell death protein 6 isoform 2
NM_013232.4	NP_037364.1	programmed cell death protein 6 isoform 1
NM_001267558.1	NP_001254487.1	programmed cell death protein 6 isoform 4

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Pdcd6	NP_001100922.1
Gallus gallus (chicken)	PDCD6	XP_004935237.1
Danio rerio (zebrafish)	pdcd6	NP_957244.1
Drosophila melanogaster (fruit fly)	Alg-2	NP_001104459.2
Neurospora crassa	NCU02738	XP_965123.1
Xenopus tropicalis (tropical clawed frog)	pdcd6	NP_001008004.1
Homo sapiens (human)	PDCD6	NP_037364.1
	LOC723043	XP_001119112.2
Bos taurus (cattle)	PDCD6	NP_001098967.1
Eremothecium gossypii	AGOS_AFR570W	NP_986117.1
Canis lupus familiaris (dog)	PDCD6	XP_851917.1
Pan troglodytes (chimpanzee)	PDCD6	XP_003950538.1
Mus musculus (house mouse)	Pdcd6	NP_035181.1
Caenorhabditis elegans (roundworm)	CELE_M04F3.4	NP_001249716.1
Magnaporthe oryzae (rice blast fungus)	MGG_04818	XP_003713748.1

Gene Ontology

The following PDCD6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PDCD6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu00930	NM_001267558.1 Latest version!	Homo sapiens programmed cell death 6 (PDCD6), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu13507	NM_013232.4 Latest version!	Homo sapiens programmed cell death 6 (PDCD6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu14125	NM_001267556.2 Latest version!	Homo sapiens programmed cell death 6 (PDCD6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu14158	NM_001267559.2 Latest version!	Homo sapiens programmed cell death 6 (PDCD6), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu09651	NM_001267557.1 Latest version!	Homo sapiens programmed cell death 6 (PDCD6), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
View Old Accession Versions >>
OHu14158	NM_001267559.1	Homo sapiens programmed cell death 6 (PDCD6), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu14125	NM_001267556.1	Homo sapiens programmed cell death 6 (PDCD6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu13507	NM_013232.3	Homo sapiens programmed cell death 6 (PDCD6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PDCD6 ( NM_001267558.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001254487.1 Homo sapiens programmed cell death 6 (PDCD6), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu00930
Clone ID Related Accession (Same CDS sequence)	NM_001267558.1
Accession Version	NM_001267558.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 366bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-25
Organism	Homo sapiens(human)
Product	programmed cell death protein 6 isoform 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK223366.1, DB495449.1 and BC012384.1. Transcript Variant: This variant (4) differs in the 5' UTR and initiates translation at a downstream, in-frame start codon, compared to variant 1. The encoded isoform (4) has a shorter N-terminus, compared to isoform 1. Sequence Note: A downstream translational start codon is selected for this RefSeq based on its better conservation in mammalian species. An upstream in-frame start codon is also present but is poorly conserved; use of the upstream start codon would result in a protein that is 32 aa longer. Leaky scanning by ribosomes may allow translation initiation at the downstream start codon. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BG714596.1, HY061490.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTTGACC GTGAGAACAA GGCCGGCGTG AACTTCAGCG AGTTCACGGG TGTGTGGAAG 
TACATCACGG ACTGGCAGAA CGTCTTCCGC ACGTACGACC GGGACAACTC CGGGATGATC 
GATAAGAACG AGCTGAAGCA GGCCCTCTCA GGTTTCGGCT ACCGGCTCTC TGACCAGTTC 
CACGACATCC TCATTCGAAA GTTTGACAGG CAGGGACGGG GGCAGATTGC CTTCGACGAC 
TTCATCCAGG GCTGCATCGT CCTGCAGAGG TTGACGGATA TATTCAGACG TTACGACACG 
GATCAGGACG GCTGGATTCA GGTGTCGTAC GAACAGTACC TGTCCATGGT CTTCAGTATC 
GTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001254487.1
CDS	226..591
Translation	MFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSIV

Target ORF information:

RefSeq Version	NM_001267558.1
Organism	Homo sapiens(human)
Definition	Homo sapiens programmed cell death 6 (PDCD6), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001267558.1

ORF Insert Sequence:

ATGTTTGACC GTGAGAACAA GGCCGGCGTG AACTTCAGCG AGTTCACGGG TGTGTGGAAG 
TACATCACGG ACTGGCAGAA CGTCTTCCGC ACGTACGACC GGGACAACTC CGGGATGATC 
GATAAGAACG AGCTGAAGCA GGCCCTCTCA GGTTTCGGCT ACCGGCTCTC TGACCAGTTC 
CACGACATCC TCATTCGAAA GTTTGACAGG CAGGGACGGG GGCAGATTGC CTTCGACGAC 
TTCATCCAGG GCTGCATCGT CCTGCAGAGG TTGACGGATA TATTCAGACG TTACGACACG 
GATCAGGACG GCTGGATTCA GGTGTCGTAC GAACAGTACC TGTCCATGGT CTTCAGTATC 
GTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PDCD6 ( NM_013232.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_037364.1 Homo sapiens programmed cell death 6 (PDCD6), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu13507
Clone ID Related Accession (Same CDS sequence)	NM_013232.3 , NM_013232.4
Accession Version	NM_013232.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 576bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-23
Organism	Homo sapiens(human)
Product	programmed cell death protein 6 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK223366.1 and BC012384.1. On or before Jun 13, 2008 this sequence version replaced XM_001714855.1, XM_001723249.1, XM_001720072.1, NM_013232.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: A downstream translational start codon is selected for this RefSeq based on its better conservation in mammalian species. An upstream in-frame start codon is also present but is poorly conserved; use of the upstream start codon would result in a protein that is 32 aa longer. Leaky scanning by ribosomes may allow translation initiation at the downstream start codon. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC012384.1, SRR1163657.575105.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: lack of evidence for use of upstream AUG ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCCGCCT ACTCTTACCG CCCCGGCCCT GGGGCCGGCC CTGGGCCTGC TGCAGGCGCG 
GCGCTGCCGG ACCAGAGCTT CCTGTGGAAC GTTTTCCAGA GGGTCGATAA AGACAGGAGT 
GGAGTGATAT CAGACACCGA GCTTCAGCAA GCTCTCTCCA ACGGCACGTG GACTCCCTTT 
AATCCAGTGA CTGTCAGGTC GATCATATCC ATGTTTGACC GTGAGAACAA GGCCGGCGTG 
AACTTCAGCG AGTTCACGGG TGTGTGGAAG TACATCACGG ACTGGCAGAA CGTCTTCCGC 
ACGTACGACC GGGACAACTC CGGGATGATC GATAAGAACG AGCTGAAGCA GGCCCTCTCA 
GGTTTCGGCT ACCGGCTCTC TGACCAGTTC CACGACATCC TCATTCGAAA GTTTGACAGG 
CAGGGACGGG GGCAGATTGC CTTCGACGAC TTCATCCAGG GCTGCATCGT CCTGCAGAGG 
TTGACGGATA TATTCAGACG TTACGACACG GATCAGGACG GCTGGATTCA GGTGTCGTAC 
GAACAGTACC TGTCCATGGT CTTCAGTATC GTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_037364.1
CDS	101..676
Translation	MAAYSYRPGPGAGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSIV

Target ORF information:

RefSeq Version	NM_013232.3
Organism	Homo sapiens(human)
Definition	Homo sapiens programmed cell death 6 (PDCD6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013232.3

ORF Insert Sequence:

ATGGCCGCCT ACTCTTACCG CCCCGGCCCT GGGGCCGGCC CTGGGCCTGC TGCAGGCGCG 
GCGCTGCCGG ACCAGAGCTT CCTGTGGAAC GTTTTCCAGA GGGTCGATAA AGACAGGAGT 
GGAGTGATAT CAGACACCGA GCTTCAGCAA GCTCTCTCCA ACGGCACGTG GACTCCCTTT 
AATCCAGTGA CTGTCAGGTC GATCATATCC ATGTTTGACC GTGAGAACAA GGCCGGCGTG 
AACTTCAGCG AGTTCACGGG TGTGTGGAAG TACATCACGG ACTGGCAGAA CGTCTTCCGC 
ACGTACGACC GGGACAACTC CGGGATGATC GATAAGAACG AGCTGAAGCA GGCCCTCTCA 
GGTTTCGGCT ACCGGCTCTC TGACCAGTTC CACGACATCC TCATTCGAAA GTTTGACAGG 
CAGGGACGGG GGCAGATTGC CTTCGACGAC TTCATCCAGG GCTGCATCGT CCTGCAGAGG 
TTGACGGATA TATTCAGACG TTACGACACG GATCAGGACG GCTGGATTCA GGTGTCGTAC 
GAACAGTACC TGTCCATGGT CTTCAGTATC GTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PDCD6 ( NM_013232.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_037364.1 Homo sapiens programmed cell death 6 (PDCD6), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu13507
Clone ID Related Accession (Same CDS sequence)	NM_013232.3 , NM_013232.4
Accession Version	NM_013232.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 576bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-25
Organism	Homo sapiens(human)
Product	programmed cell death protein 6 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK223366.1 and BC012384.1. On Nov 24, 2018 this sequence version replaced NM_013232.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: A downstream translational start codon is selected for this RefSeq based on its better conservation in mammalian species. An upstream in-frame start codon is also present but is poorly conserved; use of the upstream start codon would result in a protein that is 32 aa longer. Leaky scanning by ribosomes may allow translation initiation at the downstream start codon. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189667.253523.1, SRR5189667.50959.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000264933.9/ ENSP00000264933.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCGCCT ACTCTTACCG CCCCGGCCCT GGGGCCGGCC CTGGGCCTGC TGCAGGCGCG 
GCGCTGCCGG ACCAGAGCTT CCTGTGGAAC GTTTTCCAGA GGGTCGATAA AGACAGGAGT 
GGAGTGATAT CAGACACCGA GCTTCAGCAA GCTCTCTCCA ACGGCACGTG GACTCCCTTT 
AATCCAGTGA CTGTCAGGTC GATCATATCC ATGTTTGACC GTGAGAACAA GGCCGGCGTG 
AACTTCAGCG AGTTCACGGG TGTGTGGAAG TACATCACGG ACTGGCAGAA CGTCTTCCGC 
ACGTACGACC GGGACAACTC CGGGATGATC GATAAGAACG AGCTGAAGCA GGCCCTCTCA 
GGTTTCGGCT ACCGGCTCTC TGACCAGTTC CACGACATCC TCATTCGAAA GTTTGACAGG 
CAGGGACGGG GGCAGATTGC CTTCGACGAC TTCATCCAGG GCTGCATCGT CCTGCAGAGG 
TTGACGGATA TATTCAGACG TTACGACACG GATCAGGACG GCTGGATTCA GGTGTCGTAC 
GAACAGTACC TGTCCATGGT CTTCAGTATC GTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_037364.1
CDS	76..651
Translation	MAAYSYRPGPGAGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSIV

Target ORF information:

RefSeq Version	NM_013232.4
Organism	Homo sapiens(human)
Definition	Homo sapiens programmed cell death 6 (PDCD6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013232.4

ORF Insert Sequence:

ATGGCCGCCT ACTCTTACCG CCCCGGCCCT GGGGCCGGCC CTGGGCCTGC TGCAGGCGCG 
GCGCTGCCGG ACCAGAGCTT CCTGTGGAAC GTTTTCCAGA GGGTCGATAA AGACAGGAGT 
GGAGTGATAT CAGACACCGA GCTTCAGCAA GCTCTCTCCA ACGGCACGTG GACTCCCTTT 
AATCCAGTGA CTGTCAGGTC GATCATATCC ATGTTTGACC GTGAGAACAA GGCCGGCGTG 
AACTTCAGCG AGTTCACGGG TGTGTGGAAG TACATCACGG ACTGGCAGAA CGTCTTCCGC 
ACGTACGACC GGGACAACTC CGGGATGATC GATAAGAACG AGCTGAAGCA GGCCCTCTCA 
GGTTTCGGCT ACCGGCTCTC TGACCAGTTC CACGACATCC TCATTCGAAA GTTTGACAGG 
CAGGGACGGG GGCAGATTGC CTTCGACGAC TTCATCCAGG GCTGCATCGT CCTGCAGAGG 
TTGACGGATA TATTCAGACG TTACGACACG GATCAGGACG GCTGGATTCA GGTGTCGTAC 
GAACAGTACC TGTCCATGGT CTTCAGTATC GTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PDCD6 ( NM_001267556.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001254485.1 Homo sapiens programmed cell death 6 (PDCD6), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu14125
Clone ID Related Accession (Same CDS sequence)	NM_001267556.1 , NM_001267556.2
Accession Version	NM_001267556.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 570bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	programmed cell death protein 6 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK223366.1, BC110291.1 and BC012384.1. Transcript Variant: This variant (2) uses an alternate splice site in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Sequence Note: A downstream translational start codon is selected for this RefSeq based on its better conservation in mammalian species. An upstream in-frame start codon is also present but is poorly conserved; use of the upstream start codon would result in a protein that is 32 aa longer. Leaky scanning by ribosomes may allow translation initiation at the downstream start codon. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.295003.1, SRR1163658.454622.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: lack of evidence for use of upstream AUG ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCCGCCT ACTCTTACCG CCCCGGCCCT GGGGCCGGCC CTGGGCCTGC TGCAGGCGCG 
GCGCTGCCGG ACCAGAGCTT CCTGTGGAAC GTTTTCCAGA GGGTCGATAA AGACAGGAGT 
GGAGTGATAT CAGACACCGA GCTTCAGCAA GCTCTCTCCA ACGGCACGTG GACTCCCTTT 
AATCCAGTGA CTGTCAGGTC GATCATATCC ATGTTTGACC GTGAGAACAA GGCCGGCGTG 
AACTTCAGCG AGTTCACGGG TGTGTGGAAG TACATCACGG ACTGGCAGAA CGTCTTCCGC 
ACGTACGACC GGGACAACTC CGGGATGATC GATAAGAACG AGCTGAAGCA GGCCCTCTCA 
GGCTACCGGC TCTCTGACCA GTTCCACGAC ATCCTCATTC GAAAGTTTGA CAGGCAGGGA 
CGGGGGCAGA TTGCCTTCGA CGACTTCATC CAGGGCTGCA TCGTCCTGCA GAGGTTGACG 
GATATATTCA GACGTTACGA CACGGATCAG GACGGCTGGA TTCAGGTGTC GTACGAACAG 
TACCTGTCCA TGGTCTTCAG TATCGTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001254485.1
CDS	101..670
Translation	MAAYSYRPGPGAGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSIV

Target ORF information:

RefSeq Version	NM_001267556.1
Organism	Homo sapiens(human)
Definition	Homo sapiens programmed cell death 6 (PDCD6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001267556.1

ORF Insert Sequence:

ATGGCCGCCT ACTCTTACCG CCCCGGCCCT GGGGCCGGCC CTGGGCCTGC TGCAGGCGCG 
GCGCTGCCGG ACCAGAGCTT CCTGTGGAAC GTTTTCCAGA GGGTCGATAA AGACAGGAGT 
GGAGTGATAT CAGACACCGA GCTTCAGCAA GCTCTCTCCA ACGGCACGTG GACTCCCTTT 
AATCCAGTGA CTGTCAGGTC GATCATATCC ATGTTTGACC GTGAGAACAA GGCCGGCGTG 
AACTTCAGCG AGTTCACGGG TGTGTGGAAG TACATCACGG ACTGGCAGAA CGTCTTCCGC 
ACGTACGACC GGGACAACTC CGGGATGATC GATAAGAACG AGCTGAAGCA GGCCCTCTCA 
GGCTACCGGC TCTCTGACCA GTTCCACGAC ATCCTCATTC GAAAGTTTGA CAGGCAGGGA 
CGGGGGCAGA TTGCCTTCGA CGACTTCATC CAGGGCTGCA TCGTCCTGCA GAGGTTGACG 
GATATATTCA GACGTTACGA CACGGATCAG GACGGCTGGA TTCAGGTGTC GTACGAACAG 
TACCTGTCCA TGGTCTTCAG TATCGTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PDCD6 ( NM_001267556.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001254485.1 Homo sapiens programmed cell death 6 (PDCD6), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu14125
Clone ID Related Accession (Same CDS sequence)	NM_001267556.1 , NM_001267556.2
Accession Version	NM_001267556.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 570bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-25
Organism	Homo sapiens(human)
Product	programmed cell death protein 6 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK223366.1, BC110291.1 and BC012384.1. On Jun 3, 2019 this sequence version replaced NM_001267556.1. Transcript Variant: This variant (2) uses an alternate splice site in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Sequence Note: A downstream translational start codon is selected for this RefSeq based on its better conservation in mammalian species. An upstream in-frame start codon is also present but is poorly conserved; use of the upstream start codon would result in a protein that is 32 aa longer. Leaky scanning by ribosomes may allow translation initiation at the downstream start codon. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189658.153920.1, SRR7410570.240716.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGCCT ACTCTTACCG CCCCGGCCCT GGGGCCGGCC CTGGGCCTGC TGCAGGCGCG 
GCGCTGCCGG ACCAGAGCTT CCTGTGGAAC GTTTTCCAGA GGGTCGATAA AGACAGGAGT 
GGAGTGATAT CAGACACCGA GCTTCAGCAA GCTCTCTCCA ACGGCACGTG GACTCCCTTT 
AATCCAGTGA CTGTCAGGTC GATCATATCC ATGTTTGACC GTGAGAACAA GGCCGGCGTG 
AACTTCAGCG AGTTCACGGG TGTGTGGAAG TACATCACGG ACTGGCAGAA CGTCTTCCGC 
ACGTACGACC GGGACAACTC CGGGATGATC GATAAGAACG AGCTGAAGCA GGCCCTCTCA 
GGCTACCGGC TCTCTGACCA GTTCCACGAC ATCCTCATTC GAAAGTTTGA CAGGCAGGGA 
CGGGGGCAGA TTGCCTTCGA CGACTTCATC CAGGGCTGCA TCGTCCTGCA GAGGTTGACG 
GATATATTCA GACGTTACGA CACGGATCAG GACGGCTGGA TTCAGGTGTC GTACGAACAG 
TACCTGTCCA TGGTCTTCAG TATCGTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001254485.1
CDS	76..645
Translation	MAAYSYRPGPGAGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSIV

Target ORF information:

RefSeq Version	NM_001267556.2
Organism	Homo sapiens(human)
Definition	Homo sapiens programmed cell death 6 (PDCD6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001267556.2

ORF Insert Sequence:

ATGGCCGCCT ACTCTTACCG CCCCGGCCCT GGGGCCGGCC CTGGGCCTGC TGCAGGCGCG 
GCGCTGCCGG ACCAGAGCTT CCTGTGGAAC GTTTTCCAGA GGGTCGATAA AGACAGGAGT 
GGAGTGATAT CAGACACCGA GCTTCAGCAA GCTCTCTCCA ACGGCACGTG GACTCCCTTT 
AATCCAGTGA CTGTCAGGTC GATCATATCC ATGTTTGACC GTGAGAACAA GGCCGGCGTG 
AACTTCAGCG AGTTCACGGG TGTGTGGAAG TACATCACGG ACTGGCAGAA CGTCTTCCGC 
ACGTACGACC GGGACAACTC CGGGATGATC GATAAGAACG AGCTGAAGCA GGCCCTCTCA 
GGCTACCGGC TCTCTGACCA GTTCCACGAC ATCCTCATTC GAAAGTTTGA CAGGCAGGGA 
CGGGGGCAGA TTGCCTTCGA CGACTTCATC CAGGGCTGCA TCGTCCTGCA GAGGTTGACG 
GATATATTCA GACGTTACGA CACGGATCAG GACGGCTGGA TTCAGGTGTC GTACGAACAG 
TACCTGTCCA TGGTCTTCAG TATCGTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PDCD6 ( NM_001267559.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001254488.1 Homo sapiens programmed cell death 6 (PDCD6), transcript variant 5, mRNA.

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CloneID	OHu14158
Clone ID Related Accession (Same CDS sequence)	NM_001267559.2 , NM_001267559.1
Accession Version	NM_001267559.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 210bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-25
Organism	Homo sapiens(human)
Product	programmed cell death protein 6 isoform 5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK223366.1, CR983268.1 and BC012384.1. On Jun 3, 2019 this sequence version replaced NM_001267559.1. Transcript Variant: This variant (5) lacks two consecutive exons in the coding region, which results in a frameshift, compared to variant 1. The encoded isoform (5) is shorter and has a distinct C-terminus, compared to isoform 1. Sequence Note: A downstream translational start codon is selected for this RefSeq based on its better conservation in mammalian species. An upstream in-frame start codon is also present but is poorly conserved; use of the upstream start codon would result in a protein that is 32 aa longer. Leaky scanning by ribosomes may allow translation initiation at the downstream start codon. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7346977.203803.1, ERR279873.1053.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGCCT ACTCTTACCG CCCCGGCCCT GGGGCCGGCC CTGGGCCTGC TGCAGGCGCG 
GCGCTGCCGG ACCAGAGCTT CCTGTGGAAC GTTTTCCAGA GGGTCGATAA AGACAGGAGT 
GGAGTGATAT CAGACACCGA GCTTCAGCAA GCTCTCTCCA ACGGCACGTG GACTCCCTTT 
AATCCAGTGA CTGTCAGGTC GATCATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001254488.1
CDS	76..285
Translation	MAAYSYRPGPGAGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSII

Target ORF information:

RefSeq Version	NM_001267559.2
Organism	Homo sapiens(human)
Definition	Homo sapiens programmed cell death 6 (PDCD6), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001267559.2

ORF Insert Sequence:

ATGGCCGCCT ACTCTTACCG CCCCGGCCCT GGGGCCGGCC CTGGGCCTGC TGCAGGCGCG 
GCGCTGCCGG ACCAGAGCTT CCTGTGGAAC GTTTTCCAGA GGGTCGATAA AGACAGGAGT 
GGAGTGATAT CAGACACCGA GCTTCAGCAA GCTCTCTCCA ACGGCACGTG GACTCCCTTT 
AATCCAGTGA CTGTCAGGTC GATCATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PDCD6 ( NM_001267559.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001254488.1 Homo sapiens programmed cell death 6 (PDCD6), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu14158
Clone ID Related Accession (Same CDS sequence)	NM_001267559.2 , NM_001267559.1
Accession Version	NM_001267559.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 210bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	programmed cell death protein 6 isoform 5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK223366.1, CR983268.1 and BC012384.1. Transcript Variant: This variant (5) lacks two consecutive exons in the coding region, which results in a frameshift, compared to variant 1. The encoded isoform (5) is shorter and has a distinct C-terminus, compared to isoform 1. Sequence Note: A downstream translational start codon is selected for this RefSeq based on its better conservation in mammalian species. An upstream in-frame start codon is also present but is poorly conserved; use of the upstream start codon would result in a protein that is 32 aa longer. Leaky scanning by ribosomes may allow translation initiation at the downstream start codon. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: ERR279873.1053.1, CB991882.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: lack of evidence for use of upstream AUG ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCCGCCT ACTCTTACCG CCCCGGCCCT GGGGCCGGCC CTGGGCCTGC TGCAGGCGCG 
GCGCTGCCGG ACCAGAGCTT CCTGTGGAAC GTTTTCCAGA GGGTCGATAA AGACAGGAGT 
GGAGTGATAT CAGACACCGA GCTTCAGCAA GCTCTCTCCA ACGGCACGTG GACTCCCTTT 
AATCCAGTGA CTGTCAGGTC GATCATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001254488.1
CDS	101..310
Translation	MAAYSYRPGPGAGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSII

Target ORF information:

RefSeq Version	NM_001267559.1
Organism	Homo sapiens(human)
Definition	Homo sapiens programmed cell death 6 (PDCD6), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001267559.1

ORF Insert Sequence:

ATGGCCGCCT ACTCTTACCG CCCCGGCCCT GGGGCCGGCC CTGGGCCTGC TGCAGGCGCG 
GCGCTGCCGG ACCAGAGCTT CCTGTGGAAC GTTTTCCAGA GGGTCGATAA AGACAGGAGT 
GGAGTGATAT CAGACACCGA GCTTCAGCAA GCTCTCTCCA ACGGCACGTG GACTCCCTTT 
AATCCAGTGA CTGTCAGGTC GATCATATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PDCD6 ( NM_001267557.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001254486.1 Homo sapiens programmed cell death 6 (PDCD6), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu09651
Clone ID Related Accession (Same CDS sequence)	NM_001267557.1
Accession Version	NM_001267557.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 372bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-25
Organism	Homo sapiens(human)
Product	programmed cell death protein 6 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK223366.1, BG390506.1 and BC012384.1. Transcript Variant: This variant (3) lacks two consecutive exons in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (3) is shorter than isoform 1. Sequence Note: A downstream translational start codon is selected for this RefSeq based on its better conservation in mammalian species. An upstream in-frame start codon is also present but is poorly conserved; use of the upstream start codon would result in a protein that is 32 aa longer. Leaky scanning by ribosomes may allow translation initiation at the downstream start codon. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.493984.1, SRR1163658.467961.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: lack of evidence for use of upstream AUG ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCCGCCT ACTCTTACCG CCCCGGCCCT GGGGCCGGCC CTGGGCCTGC TGCAGGCGCG 
GCGCTGCCGG ACCAGAGCTT CCTGTGGAAC GTTTTCCAGA GGGTCGATAA AGACAGGAGT 
GGAGTGATAT CAGACACCGA GCTTCAGCAA GCTCTCTCCA ACGGCTACCG GCTCTCTGAC 
CAGTTCCACG ACATCCTCAT TCGAAAGTTT GACAGGCAGG GACGGGGGCA GATTGCCTTC 
GACGACTTCA TCCAGGGCTG CATCGTCCTG CAGAGGTTGA CGGATATATT CAGACGTTAC 
GACACGGATC AGGACGGCTG GATTCAGGTG TCGTACGAAC AGTACCTGTC CATGGTCTTC 
AGTATCGTAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001254486.1
CDS	101..472
Translation	MAAYSYRPGPGAGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDTELQQALSNGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSIV

Target ORF information:

RefSeq Version	NM_001267557.1
Organism	Homo sapiens(human)
Definition	Homo sapiens programmed cell death 6 (PDCD6), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001267557.1

ORF Insert Sequence:

ATGGCCGCCT ACTCTTACCG CCCCGGCCCT GGGGCCGGCC CTGGGCCTGC TGCAGGCGCG 
GCGCTGCCGG ACCAGAGCTT CCTGTGGAAC GTTTTCCAGA GGGTCGATAA AGACAGGAGT 
GGAGTGATAT CAGACACCGA GCTTCAGCAA GCTCTCTCCA ACGGCTACCG GCTCTCTGAC 
CAGTTCCACG ACATCCTCAT TCGAAAGTTT GACAGGCAGG GACGGGGGCA GATTGCCTTC 
GACGACTTCA TCCAGGGCTG CATCGTCCTG CAGAGGTTGA CGGATATATT CAGACGTTAC 
GACACGGATC AGGACGGCTG GATTCAGGTG TCGTACGAAC AGTACCTGTC CATGGTCTTC 
AGTATCGTAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

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PDCD6 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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