ZBTB42 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ZBTB42
Entrez Gene ID	100128927
Full Name	zinc finger and BTB domain containing 42
Synonyms	LCCS6,ZNF925
General protein information	Preferred Names zinc finger and BTB domain containing 42 Names zinc finger and BTB domain-containing protein 42
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 14 Map Location: 14q32.33
Summary	The protein encoded by this gene is a member of the C2H2 zinc finger protein family. This protein is predicted to have a pox virus and zinc finger (POZ) domain at the N-terminus and four zinc finger domains at the C-terminus. In human and mouse, the protein localizes to the nuclei of skeletal muscle cells. Knockdown of this gene in zebrafish results in abnormal skeletal muscle development and myofibrillar disorganization. A novel homozygous variant of the human gene has been associated with lethal congenital contracture syndrome, an autosomal recessive disorder that results in muscle wasting. [provided by RefSeq, Mar 2015]. COMPLETENESS: complete on the 3' end.
Disorder MIM:	613915
Disorder Html:	?Lethal congenital contracture syndrome 6, 616248 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001137601.2	NP_001131073.1	zinc finger and BTB domain-containing protein 42
NM_001137601.3	NP_001131073.1	zinc finger and BTB domain-containing protein 42
XM_017020911.1	XP_016876400.1	zinc finger and BTB domain-containing protein 42 isoform X1
NM_001370342.1	NP_001357271.1	zinc finger and BTB domain-containing protein 42

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	ZBTB42	XP_003314583.1
Rattus norvegicus (Norway rat)	Zbtb42	NP_001119774.1
Homo sapiens (human)	ZBTB42	NP_001131073.1
	ZBTB42	XP_001095408.2
Bos taurus (cattle)	ZBTB42	XP_005222402.1
Mus musculus (house mouse)	Zbtb42	NP_001093930.1

Gene Ontology
Bibliography

Related articles in PubMed

ZBTB42 mutation defines a novel lethal congenital contracture syndrome (LCCS6).
Patel N, Smith LL, Faqeih E, Mohamed J, Gupta VA, Alkuraya FS
Human molecular genetics23(24)6584-93(2014 Dec)

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Gaudet P, Livstone MS, Lewis SE, Thomas PD
Briefings in bioinformatics12(5)449-62(2011 Sep)

Characterization of the ZBTB42 gene in humans and mice.
Devaney SA, Mate SE, Devaney JM, Hoffman EP
Human genetics129(4)433-41(2011 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

ZBTB42 mutation defines a novel lethal congenital contracture syndrome.
Title: ZBTB42 mutation defines a novel lethal congenital contracture syndrome (LCCS6).

Data show that ZBTB42 protein is expressed in human skeletal muscle and a murine cell line C2C12 myotubes.
Title: Characterization of the ZBTB42 gene in humans and mice.

Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.

Observational study of gene-disease association. (HuGE Navigator)
Title: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.

The following ZBTB42 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ZBTB42 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu24800	NM_001137601.3 Latest version!	Homo sapiens zinc finger and BTB domain containing 42 (ZBTB42), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu24800	NM_001370342.1 Latest version!	Homo sapiens zinc finger and BTB domain containing 42 (ZBTB42), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu24800	XM_017020911.1 Latest version!	Homo sapiens zinc finger and BTB domain containing 42 (ZBTB42), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu24800	NM_001137601.2	Homo sapiens zinc finger and BTB domain containing 42 (ZBTB42), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ZBTB42 ( NM_001137601.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001131073.1 Homo sapiens zinc finger and BTB domain containing 42 (ZBTB42), mRNA.

Price & Availability↑

CloneID	OHu24800
Clone ID Related Accession (Same CDS sequence)	NM_001137601.2 , NM_001137601.3 , XM_017020911.1 , NM_001370342.1
Accession Version	NM_001137601.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1269bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	zinc finger and BTB domain-containing protein 42
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC157833.1, AL590327.3, AK125003.1 and AL138144.1. This sequence is a reference standard in the RefSeqGene project. On Mar 31, 2015 this sequence version replaced NM_001137601.1. COMPLETENESS: complete on the 3' end.

ATGGAGTTCC CTGAGCACGG CGGACGGCTG CTGGGCCGCC TGAGACAGCA GCGCGAGCTG 
GGCTTCCTAT GCGACTGCAC CGTGCTGGTG GGCGACGCGC GCTTCCCGGC CCACCGTGCC 
GTGCTGGCCG CGTGCAGCGT CTACTTCCAT CTCTTCTACA GGGACCGGCC CGCGGGCAGT 
CGCGACACGG TGCGGCTCAA CGGCGACATC GTCACGGCGC CCGCCTTCGG CCGCCTACTG 
GACTTCATGT ACGAGGGCCG CCTGGACCTG CGCAGCCTGC CTGTGGAGGA CGTCCTGGCA 
GCCGCCAGCT ACCTGCACAT GTATGACATC GTCAAGGTCT GCAAGGGCAG GCTCCAGGAG 
AAGGATCGAA GTCTGGACCC GGGGAACCCT GCCCCTGGGG CAGAACCTGC TCAGCCACCG 
TGCCCCTGGC CTGTCTGGAC CGCGGACCTC TGCCCAGCTG CCCGAAAGGC CAAGCTCCCC 
CCGTTTGGGG TCAAGGCTGC CCTCCCTCCT CGAGCATCTG GGCCTCCTCC CTGCCAGGTC 
CCAGAAGAGT CAGACCAGGC CCTGGACCTG TCGTTGAAGT CTGGCCCAAG GCAGGAGCGG 
GTCCACCCAC CGTGCGTCCT CCAGACACCC CTCTGCAGCC AGAGGCAGCC AGGGGCCCAG 
CCACTGGTGA AGGACGAACG GGACTCACTG TCCGAACAGG AGGAGAGCAG CAGCTCTAGG 
AGCCCCCACA GTCCCCCGAA GCCACCTCCT GTTCCTGCAG CCAAGGGCCT GGTGGTGGGC 
TTGCAGCCGC TGCCCCTCAG CGGAGAGGGC AGCCGGGAGC TGGAGCTTGG TGCAGGGCGA 
CTGGCGAGTG AGGACGAGCT GGGGCCTGGT GGGCCCCTCT GCATCTGCCC GTTGTGCAGC 
AAGCTGTTTC CCAGCTCCCA CGTGCTGCAG CTGCACCTCA GTGCCCACTT CCGTGAGCGA 
GACAGCACCC GGGCCCGGCT CTCACCCGAC GGCGTGGCAC CCACCTGCCC GCTCTGTGGG 
AAGACCTTCT CGTGCACATA CACACTGAAG AGGCACGAGC GGACACACTC GGGTGAGAAG 
CCCTATACGT GTGTGCAGTG TGGCAAAAGT TTTCAGTACT CCCACAACCT GAGCCGGCAC 
ACCGTAGTGC ACACTCGAGA GAAGCCGCAT GCCTGCCGGT GGTGTGAGCG CCGTTTCACG 
CAGTCCGGGG ACCTCTACCG CCACGTCCGC AAGTTTCACT GTGGCCTCGT CAAGTCCCTT 
CTGGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001131073.1
CDS	18..1286
Translation	MEFPEHGGRLLGRLRQQRELGFLCDCTVLVGDARFPAHRAVLAACSVYFHLFYRDRPAGSRDTVRLNGDIVTAPAFGRLLDFMYEGRLDLRSLPVEDVLAAASYLHMYDIVKVCKGRLQEKDRSLDPGNPAPGAEPAQPPCPWPVWTADLCPAARKAKLPPFGVKAALPPRASGPPPCQVPEESDQALDLSLKSGPRQERVHPPCVLQTPLCSQRQPGAQPLVKDERDSLSEQEESSSSRSPHSPPKPPPVPAAKGLVVGLQPLPLSGEGSRELELGAGRLASEDELGPGGPLCICPLCSKLFPSSHVLQLHLSAHFRERDSTRARLSPDGVAPTCPLCGKTFSCTYTLKRHERTHSGEKPYTCVQCGKSFQYSHNLSRHTVVHTREKPHACRWCERRFTQSGDLYRHVRKFHCGLVKSLLV

Target ORF information:

RefSeq Version	NM_001137601.2
Organism	Homo sapiens(human)
Definition	Homo sapiens zinc finger and BTB domain containing 42 (ZBTB42), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001137601.2

ORF Insert Sequence:

ATGGAGTTCC CTGAGCACGG CGGACGGCTG CTGGGCCGCC TGAGACAGCA GCGCGAGCTG 
GGCTTCCTAT GCGACTGCAC CGTGCTGGTG GGCGACGCGC GCTTCCCGGC CCACCGTGCC 
GTGCTGGCCG CGTGCAGCGT CTACTTCCAT CTCTTCTACA GGGACCGGCC CGCGGGCAGT 
CGCGACACGG TGCGGCTCAA CGGCGACATC GTCACGGCGC CCGCCTTCGG CCGCCTACTG 
GACTTCATGT ACGAGGGCCG CCTGGACCTG CGCAGCCTGC CTGTGGAGGA CGTCCTGGCA 
GCCGCCAGCT ACCTGCACAT GTATGACATC GTCAAGGTCT GCAAGGGCAG GCTCCAGGAG 
AAGGATCGAA GTCTGGACCC GGGGAACCCT GCCCCTGGGG CAGAACCTGC TCAGCCACCG 
TGCCCCTGGC CTGTCTGGAC CGCGGACCTC TGCCCAGCTG CCCGAAAGGC CAAGCTCCCC 
CCGTTTGGGG TCAAGGCTGC CCTCCCTCCT CGAGCATCTG GGCCTCCTCC CTGCCAGGTC 
CCAGAAGAGT CAGACCAGGC CCTGGACCTG TCGTTGAAGT CTGGCCCAAG GCAGGAGCGG 
GTCCACCCAC CGTGCGTCCT CCAGACACCC CTCTGCAGCC AGAGGCAGCC AGGGGCCCAG 
CCACTGGTGA AGGACGAACG GGACTCACTG TCCGAACAGG AGGAGAGCAG CAGCTCTAGG 
AGCCCCCACA GTCCCCCGAA GCCACCTCCT GTTCCTGCAG CCAAGGGCCT GGTGGTGGGC 
TTGCAGCCGC TGCCCCTCAG CGGAGAGGGC AGCCGGGAGC TGGAGCTTGG TGCAGGGCGA 
CTGGCGAGTG AGGACGAGCT GGGGCCTGGT GGGCCCCTCT GCATCTGCCC GTTGTGCAGC 
AAGCTGTTTC CCAGCTCCCA CGTGCTGCAG CTGCACCTCA GTGCCCACTT CCGTGAGCGA 
GACAGCACCC GGGCCCGGCT CTCACCCGAC GGCGTGGCAC CCACCTGCCC GCTCTGTGGG 
AAGACCTTCT CGTGCACATA CACACTGAAG AGGCACGAGC GGACACACTC GGGTGAGAAG 
CCCTATACGT GTGTGCAGTG TGGCAAAAGT TTTCAGTACT CCCACAACCT GAGCCGGCAC 
ACCGTAGTGC ACACTCGAGA GAAGCCGCAT GCCTGCCGGT GGTGTGAGCG CCGTTTCACG 
CAGTCCGGGG ACCTCTACCG CCACGTCCGC AAGTTTCACT GTGGCCTCGT CAAGTCCCTT 
CTGGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ZBTB42 ( NM_001137601.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001131073.1 Homo sapiens zinc finger and BTB domain containing 42 (ZBTB42), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu24800
Clone ID Related Accession (Same CDS sequence)	NM_001137601.2 , NM_001137601.3 , XM_017020911.1 , NM_001370342.1
Accession Version	NM_001137601.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1269bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-21
Organism	Homo sapiens(human)
Product	zinc finger and BTB domain-containing protein 42
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL590327.3, BC157833.1, AK125003.1 and AL138144.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_001137601.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript is intronless :: BC171822.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000342537.8/ ENSP00000409107.2 RefSeq Select criteria :: based on conservation, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGTTCC CTGAGCACGG CGGACGGCTG CTGGGCCGCC TGAGACAGCA GCGCGAGCTG 
GGCTTCCTAT GCGACTGCAC CGTGCTGGTG GGCGACGCGC GCTTCCCGGC CCACCGTGCC 
GTGCTGGCCG CGTGCAGCGT CTACTTCCAT CTCTTCTACA GGGACCGGCC CGCGGGCAGT 
CGCGACACGG TGCGGCTCAA CGGCGACATC GTCACGGCGC CCGCCTTCGG CCGCCTACTG 
GACTTCATGT ACGAGGGCCG CCTGGACCTG CGCAGCCTGC CTGTGGAGGA CGTCCTGGCA 
GCCGCCAGCT ACCTGCACAT GTATGACATC GTCAAGGTCT GCAAGGGCAG GCTCCAGGAG 
AAGGATCGAA GTCTGGACCC GGGGAACCCT GCCCCTGGGG CAGAACCTGC TCAGCCACCG 
TGCCCCTGGC CTGTCTGGAC CGCGGACCTC TGCCCAGCTG CCCGAAAGGC CAAGCTCCCC 
CCGTTTGGGG TCAAGGCTGC CCTCCCTCCT CGAGCATCTG GGCCTCCTCC CTGCCAGGTC 
CCAGAAGAGT CAGACCAGGC CCTGGACCTG TCGTTGAAGT CTGGCCCAAG GCAGGAGCGG 
GTCCACCCAC CGTGCGTCCT CCAGACACCC CTCTGCAGCC AGAGGCAGCC AGGGGCCCAG 
CCACTGGTGA AGGACGAACG GGACTCACTG TCCGAACAGG AGGAGAGCAG CAGCTCTAGG 
AGCCCCCACA GTCCCCCGAA GCCACCTCCT GTTCCTGCAG CCAAGGGCCT GGTGGTGGGC 
TTGCAGCCGC TGCCCCTCAG CGGAGAGGGC AGCCGGGAGC TGGAGCTTGG TGCAGGGCGA 
CTGGCGAGTG AGGACGAGCT GGGGCCTGGT GGGCCCCTCT GCATCTGCCC GTTGTGCAGC 
AAGCTGTTTC CCAGCTCCCA CGTGCTGCAG CTGCACCTCA GTGCCCACTT CCGTGAGCGA 
GACAGCACCC GGGCCCGGCT CTCACCCGAC GGCGTGGCAC CCACCTGCCC GCTCTGTGGG 
AAGACCTTCT CGTGCACATA CACACTGAAG AGGCACGAGC GGACACACTC GGGTGAGAAG 
CCCTATACGT GTGTGCAGTG TGGCAAAAGT TTTCAGTACT CCCACAACCT GAGCCGGCAC 
ACCGTAGTGC ACACTCGAGA GAAGCCGCAT GCCTGCCGGT GGTGTGAGCG CCGTTTCACG 
CAGTCCGGGG ACCTCTACCG CCACGTCCGC AAGTTTCACT GTGGCCTCGT CAAGTCCCTT 
CTGGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001131073.1
CDS	98..1366
Translation	MEFPEHGGRLLGRLRQQRELGFLCDCTVLVGDARFPAHRAVLAACSVYFHLFYRDRPAGSRDTVRLNGDIVTAPAFGRLLDFMYEGRLDLRSLPVEDVLAAASYLHMYDIVKVCKGRLQEKDRSLDPGNPAPGAEPAQPPCPWPVWTADLCPAARKAKLPPFGVKAALPPRASGPPPCQVPEESDQALDLSLKSGPRQERVHPPCVLQTPLCSQRQPGAQPLVKDERDSLSEQEESSSSRSPHSPPKPPPVPAAKGLVVGLQPLPLSGEGSRELELGAGRLASEDELGPGGPLCICPLCSKLFPSSHVLQLHLSAHFRERDSTRARLSPDGVAPTCPLCGKTFSCTYTLKRHERTHSGEKPYTCVQCGKSFQYSHNLSRHTVVHTREKPHACRWCERRFTQSGDLYRHVRKFHCGLVKSLLV

Target ORF information:

RefSeq Version	NM_001137601.3
Organism	Homo sapiens(human)
Definition	Homo sapiens zinc finger and BTB domain containing 42 (ZBTB42), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001137601.3

ORF Insert Sequence:

ATGGAGTTCC CTGAGCACGG CGGACGGCTG CTGGGCCGCC TGAGACAGCA GCGCGAGCTG 
GGCTTCCTAT GCGACTGCAC CGTGCTGGTG GGCGACGCGC GCTTCCCGGC CCACCGTGCC 
GTGCTGGCCG CGTGCAGCGT CTACTTCCAT CTCTTCTACA GGGACCGGCC CGCGGGCAGT 
CGCGACACGG TGCGGCTCAA CGGCGACATC GTCACGGCGC CCGCCTTCGG CCGCCTACTG 
GACTTCATGT ACGAGGGCCG CCTGGACCTG CGCAGCCTGC CTGTGGAGGA CGTCCTGGCA 
GCCGCCAGCT ACCTGCACAT GTATGACATC GTCAAGGTCT GCAAGGGCAG GCTCCAGGAG 
AAGGATCGAA GTCTGGACCC GGGGAACCCT GCCCCTGGGG CAGAACCTGC TCAGCCACCG 
TGCCCCTGGC CTGTCTGGAC CGCGGACCTC TGCCCAGCTG CCCGAAAGGC CAAGCTCCCC 
CCGTTTGGGG TCAAGGCTGC CCTCCCTCCT CGAGCATCTG GGCCTCCTCC CTGCCAGGTC 
CCAGAAGAGT CAGACCAGGC CCTGGACCTG TCGTTGAAGT CTGGCCCAAG GCAGGAGCGG 
GTCCACCCAC CGTGCGTCCT CCAGACACCC CTCTGCAGCC AGAGGCAGCC AGGGGCCCAG 
CCACTGGTGA AGGACGAACG GGACTCACTG TCCGAACAGG AGGAGAGCAG CAGCTCTAGG 
AGCCCCCACA GTCCCCCGAA GCCACCTCCT GTTCCTGCAG CCAAGGGCCT GGTGGTGGGC 
TTGCAGCCGC TGCCCCTCAG CGGAGAGGGC AGCCGGGAGC TGGAGCTTGG TGCAGGGCGA 
CTGGCGAGTG AGGACGAGCT GGGGCCTGGT GGGCCCCTCT GCATCTGCCC GTTGTGCAGC 
AAGCTGTTTC CCAGCTCCCA CGTGCTGCAG CTGCACCTCA GTGCCCACTT CCGTGAGCGA 
GACAGCACCC GGGCCCGGCT CTCACCCGAC GGCGTGGCAC CCACCTGCCC GCTCTGTGGG 
AAGACCTTCT CGTGCACATA CACACTGAAG AGGCACGAGC GGACACACTC GGGTGAGAAG 
CCCTATACGT GTGTGCAGTG TGGCAAAAGT TTTCAGTACT CCCACAACCT GAGCCGGCAC 
ACCGTAGTGC ACACTCGAGA GAAGCCGCAT GCCTGCCGGT GGTGTGAGCG CCGTTTCACG 
CAGTCCGGGG ACCTCTACCG CCACGTCCGC AAGTTTCACT GTGGCCTCGT CAAGTCCCTT 
CTGGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ZBTB42 ( NM_001370342.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001357271.1 Homo sapiens zinc finger and BTB domain containing 42 (ZBTB42), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu24800
Clone ID Related Accession (Same CDS sequence)	NM_001137601.2 , NM_001137601.3 , XM_017020911.1 , NM_001370342.1
Accession Version	NM_001370342.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1269bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-06
Organism	Homo sapiens(human)
Product	zinc finger and BTB domain-containing protein 42
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL590327.3. On May 7, 2019 this sequence version replaced XM_017020911.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END##

ATGGAGTTCC CTGAGCACGG CGGACGGCTG CTGGGCCGCC TGAGACAGCA GCGCGAGCTG 
GGCTTCCTAT GCGACTGCAC CGTGCTGGTG GGCGACGCGC GCTTCCCGGC CCACCGTGCC 
GTGCTGGCCG CGTGCAGCGT CTACTTCCAT CTCTTCTACA GGGACCGGCC CGCGGGCAGT 
CGCGACACGG TGCGGCTCAA CGGCGACATC GTCACGGCGC CCGCCTTCGG CCGCCTACTG 
GACTTCATGT ACGAGGGCCG CCTGGACCTG CGCAGCCTGC CTGTGGAGGA CGTCCTGGCA 
GCCGCCAGCT ACCTGCACAT GTATGACATC GTCAAGGTCT GCAAGGGCAG GCTCCAGGAG 
AAGGATCGAA GTCTGGACCC GGGGAACCCT GCCCCTGGGG CAGAACCTGC TCAGCCACCG 
TGCCCCTGGC CTGTCTGGAC CGCGGACCTC TGCCCAGCTG CCCGAAAGGC CAAGCTCCCC 
CCGTTTGGGG TCAAGGCTGC CCTCCCTCCT CGAGCATCTG GGCCTCCTCC CTGCCAGGTC 
CCAGAAGAGT CAGACCAGGC CCTGGACCTG TCGTTGAAGT CTGGCCCAAG GCAGGAGCGG 
GTCCACCCAC CGTGCGTCCT CCAGACACCC CTCTGCAGCC AGAGGCAGCC AGGGGCCCAG 
CCACTGGTGA AGGACGAACG GGACTCACTG TCCGAACAGG AGGAGAGCAG CAGCTCTAGG 
AGCCCCCACA GTCCCCCGAA GCCACCTCCT GTTCCTGCAG CCAAGGGCCT GGTGGTGGGC 
TTGCAGCCGC TGCCCCTCAG CGGAGAGGGC AGCCGGGAGC TGGAGCTTGG TGCAGGGCGA 
CTGGCGAGTG AGGACGAGCT GGGGCCTGGT GGGCCCCTCT GCATCTGCCC GTTGTGCAGC 
AAGCTGTTTC CCAGCTCCCA CGTGCTGCAG CTGCACCTCA GTGCCCACTT CCGTGAGCGA 
GACAGCACCC GGGCCCGGCT CTCACCCGAC GGCGTGGCAC CCACCTGCCC GCTCTGTGGG 
AAGACCTTCT CGTGCACATA CACACTGAAG AGGCACGAGC GGACACACTC GGGTGAGAAG 
CCCTATACGT GTGTGCAGTG TGGCAAAAGT TTTCAGTACT CCCACAACCT GAGCCGGCAC 
ACCGTAGTGC ACACTCGAGA GAAGCCGCAT GCCTGCCGGT GGTGTGAGCG CCGTTTCACG 
CAGTCCGGGG ACCTCTACCG CCACGTCCGC AAGTTTCACT GTGGCCTCGT CAAGTCCCTT 
CTGGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001357271.1
CDS	165..1433
Translation	MEFPEHGGRLLGRLRQQRELGFLCDCTVLVGDARFPAHRAVLAACSVYFHLFYRDRPAGSRDTVRLNGDIVTAPAFGRLLDFMYEGRLDLRSLPVEDVLAAASYLHMYDIVKVCKGRLQEKDRSLDPGNPAPGAEPAQPPCPWPVWTADLCPAARKAKLPPFGVKAALPPRASGPPPCQVPEESDQALDLSLKSGPRQERVHPPCVLQTPLCSQRQPGAQPLVKDERDSLSEQEESSSSRSPHSPPKPPPVPAAKGLVVGLQPLPLSGEGSRELELGAGRLASEDELGPGGPLCICPLCSKLFPSSHVLQLHLSAHFRERDSTRARLSPDGVAPTCPLCGKTFSCTYTLKRHERTHSGEKPYTCVQCGKSFQYSHNLSRHTVVHTREKPHACRWCERRFTQSGDLYRHVRKFHCGLVKSLLV

Target ORF information:

RefSeq Version	NM_001370342.1
Organism	Homo sapiens(human)
Definition	Homo sapiens zinc finger and BTB domain containing 42 (ZBTB42), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001370342.1

ORF Insert Sequence:

ATGGAGTTCC CTGAGCACGG CGGACGGCTG CTGGGCCGCC TGAGACAGCA GCGCGAGCTG 
GGCTTCCTAT GCGACTGCAC CGTGCTGGTG GGCGACGCGC GCTTCCCGGC CCACCGTGCC 
GTGCTGGCCG CGTGCAGCGT CTACTTCCAT CTCTTCTACA GGGACCGGCC CGCGGGCAGT 
CGCGACACGG TGCGGCTCAA CGGCGACATC GTCACGGCGC CCGCCTTCGG CCGCCTACTG 
GACTTCATGT ACGAGGGCCG CCTGGACCTG CGCAGCCTGC CTGTGGAGGA CGTCCTGGCA 
GCCGCCAGCT ACCTGCACAT GTATGACATC GTCAAGGTCT GCAAGGGCAG GCTCCAGGAG 
AAGGATCGAA GTCTGGACCC GGGGAACCCT GCCCCTGGGG CAGAACCTGC TCAGCCACCG 
TGCCCCTGGC CTGTCTGGAC CGCGGACCTC TGCCCAGCTG CCCGAAAGGC CAAGCTCCCC 
CCGTTTGGGG TCAAGGCTGC CCTCCCTCCT CGAGCATCTG GGCCTCCTCC CTGCCAGGTC 
CCAGAAGAGT CAGACCAGGC CCTGGACCTG TCGTTGAAGT CTGGCCCAAG GCAGGAGCGG 
GTCCACCCAC CGTGCGTCCT CCAGACACCC CTCTGCAGCC AGAGGCAGCC AGGGGCCCAG 
CCACTGGTGA AGGACGAACG GGACTCACTG TCCGAACAGG AGGAGAGCAG CAGCTCTAGG 
AGCCCCCACA GTCCCCCGAA GCCACCTCCT GTTCCTGCAG CCAAGGGCCT GGTGGTGGGC 
TTGCAGCCGC TGCCCCTCAG CGGAGAGGGC AGCCGGGAGC TGGAGCTTGG TGCAGGGCGA 
CTGGCGAGTG AGGACGAGCT GGGGCCTGGT GGGCCCCTCT GCATCTGCCC GTTGTGCAGC 
AAGCTGTTTC CCAGCTCCCA CGTGCTGCAG CTGCACCTCA GTGCCCACTT CCGTGAGCGA 
GACAGCACCC GGGCCCGGCT CTCACCCGAC GGCGTGGCAC CCACCTGCCC GCTCTGTGGG 
AAGACCTTCT CGTGCACATA CACACTGAAG AGGCACGAGC GGACACACTC GGGTGAGAAG 
CCCTATACGT GTGTGCAGTG TGGCAAAAGT TTTCAGTACT CCCACAACCT GAGCCGGCAC 
ACCGTAGTGC ACACTCGAGA GAAGCCGCAT GCCTGCCGGT GGTGTGAGCG CCGTTTCACG 
CAGTCCGGGG ACCTCTACCG CCACGTCCGC AAGTTTCACT GTGGCCTCGT CAAGTCCCTT 
CTGGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ZBTB42 ( XM_017020911.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016876400.1 Homo sapiens zinc finger and BTB domain containing 42 (ZBTB42), transcript variant X1, mRNA.

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CloneID	OHu24800
Clone ID Related Accession (Same CDS sequence)	NM_001137601.2 , NM_001137601.3 , XM_017020911.1 , NM_001370342.1
Accession Version	XM_017020911.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1269bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-25
Organism	Homo sapiens(human)
Product	zinc finger and BTB domain-containing protein 42 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000014.9) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Homo sapiens Annotation Release 109 Annotation Version :: 109 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGTTCC CTGAGCACGG CGGACGGCTG CTGGGCCGCC TGAGACAGCA GCGCGAGCTG 
GGCTTCCTAT GCGACTGCAC CGTGCTGGTG GGCGACGCGC GCTTCCCGGC CCACCGTGCC 
GTGCTGGCCG CGTGCAGCGT CTACTTCCAT CTCTTCTACA GGGACCGGCC CGCGGGCAGT 
CGCGACACGG TGCGGCTCAA CGGCGACATC GTCACGGCGC CCGCCTTCGG CCGCCTACTG 
GACTTCATGT ACGAGGGCCG CCTGGACCTG CGCAGCCTGC CTGTGGAGGA CGTCCTGGCA 
GCCGCCAGCT ACCTGCACAT GTATGACATC GTCAAGGTCT GCAAGGGCAG GCTCCAGGAG 
AAGGATCGAA GTCTGGACCC GGGGAACCCT GCCCCTGGGG CAGAACCTGC TCAGCCACCG 
TGCCCCTGGC CTGTCTGGAC CGCGGACCTC TGCCCAGCTG CCCGAAAGGC CAAGCTCCCC 
CCGTTTGGGG TCAAGGCTGC CCTCCCTCCT CGAGCATCTG GGCCTCCTCC CTGCCAGGTC 
CCAGAAGAGT CAGACCAGGC CCTGGACCTG TCGTTGAAGT CTGGCCCAAG GCAGGAGCGG 
GTCCACCCAC CGTGCGTCCT CCAGACACCC CTCTGCAGCC AGAGGCAGCC AGGGGCCCAG 
CCACTGGTGA AGGACGAACG GGACTCACTG TCCGAACAGG AGGAGAGCAG CAGCTCTAGG 
AGCCCCCACA GTCCCCCGAA GCCACCTCCT GTTCCTGCAG CCAAGGGCCT GGTGGTGGGC 
TTGCAGCCGC TGCCCCTCAG CGGAGAGGGC AGCCGGGAGC TGGAGCTTGG TGCAGGGCGA 
CTGGCGAGTG AGGACGAGCT GGGGCCTGGT GGGCCCCTCT GCATCTGCCC GTTGTGCAGC 
AAGCTGTTTC CCAGCTCCCA CGTGCTGCAG CTGCACCTCA GTGCCCACTT CCGTGAGCGA 
GACAGCACCC GGGCCCGGCT CTCACCCGAC GGCGTGGCAC CCACCTGCCC GCTCTGTGGG 
AAGACCTTCT CGTGCACATA CACACTGAAG AGGCACGAGC GGACACACTC GGGTGAGAAG 
CCCTATACGT GTGTGCAGTG TGGCAAAAGT TTTCAGTACT CCCACAACCT GAGCCGGCAC 
ACCGTAGTGC ACACTCGAGA GAAGCCGCAT GCCTGCCGGT GGTGTGAGCG CCGTTTCACG 
CAGTCCGGGG ACCTCTACCG CCACGTCCGC AAGTTTCACT GTGGCCTCGT CAAGTCCCTT 
CTGGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016876400.1
CDS	122..1390
Translation	MEFPEHGGRLLGRLRQQRELGFLCDCTVLVGDARFPAHRAVLAACSVYFHLFYRDRPAGSRDTVRLNGDIVTAPAFGRLLDFMYEGRLDLRSLPVEDVLAAASYLHMYDIVKVCKGRLQEKDRSLDPGNPAPGAEPAQPPCPWPVWTADLCPAARKAKLPPFGVKAALPPRASGPPPCQVPEESDQALDLSLKSGPRQERVHPPCVLQTPLCSQRQPGAQPLVKDERDSLSEQEESSSSRSPHSPPKPPPVPAAKGLVVGLQPLPLSGEGSRELELGAGRLASEDELGPGGPLCICPLCSKLFPSSHVLQLHLSAHFRERDSTRARLSPDGVAPTCPLCGKTFSCTYTLKRHERTHSGEKPYTCVQCGKSFQYSHNLSRHTVVHTREKPHACRWCERRFTQSGDLYRHVRKFHCGLVKSLLV

Target ORF information:

RefSeq Version	XM_017020911.1
Organism	Homo sapiens(human)
Definition	Homo sapiens zinc finger and BTB domain containing 42 (ZBTB42), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017020911.1

ORF Insert Sequence:

ATGGAGTTCC CTGAGCACGG CGGACGGCTG CTGGGCCGCC TGAGACAGCA GCGCGAGCTG 
GGCTTCCTAT GCGACTGCAC CGTGCTGGTG GGCGACGCGC GCTTCCCGGC CCACCGTGCC 
GTGCTGGCCG CGTGCAGCGT CTACTTCCAT CTCTTCTACA GGGACCGGCC CGCGGGCAGT 
CGCGACACGG TGCGGCTCAA CGGCGACATC GTCACGGCGC CCGCCTTCGG CCGCCTACTG 
GACTTCATGT ACGAGGGCCG CCTGGACCTG CGCAGCCTGC CTGTGGAGGA CGTCCTGGCA 
GCCGCCAGCT ACCTGCACAT GTATGACATC GTCAAGGTCT GCAAGGGCAG GCTCCAGGAG 
AAGGATCGAA GTCTGGACCC GGGGAACCCT GCCCCTGGGG CAGAACCTGC TCAGCCACCG 
TGCCCCTGGC CTGTCTGGAC CGCGGACCTC TGCCCAGCTG CCCGAAAGGC CAAGCTCCCC 
CCGTTTGGGG TCAAGGCTGC CCTCCCTCCT CGAGCATCTG GGCCTCCTCC CTGCCAGGTC 
CCAGAAGAGT CAGACCAGGC CCTGGACCTG TCGTTGAAGT CTGGCCCAAG GCAGGAGCGG 
GTCCACCCAC CGTGCGTCCT CCAGACACCC CTCTGCAGCC AGAGGCAGCC AGGGGCCCAG 
CCACTGGTGA AGGACGAACG GGACTCACTG TCCGAACAGG AGGAGAGCAG CAGCTCTAGG 
AGCCCCCACA GTCCCCCGAA GCCACCTCCT GTTCCTGCAG CCAAGGGCCT GGTGGTGGGC 
TTGCAGCCGC TGCCCCTCAG CGGAGAGGGC AGCCGGGAGC TGGAGCTTGG TGCAGGGCGA 
CTGGCGAGTG AGGACGAGCT GGGGCCTGGT GGGCCCCTCT GCATCTGCCC GTTGTGCAGC 
AAGCTGTTTC CCAGCTCCCA CGTGCTGCAG CTGCACCTCA GTGCCCACTT CCGTGAGCGA 
GACAGCACCC GGGCCCGGCT CTCACCCGAC GGCGTGGCAC CCACCTGCCC GCTCTGTGGG 
AAGACCTTCT CGTGCACATA CACACTGAAG AGGCACGAGC GGACACACTC GGGTGAGAAG 
CCCTATACGT GTGTGCAGTG TGGCAAAAGT TTTCAGTACT CCCACAACCT GAGCCGGCAC 
ACCGTAGTGC ACACTCGAGA GAAGCCGCAT GCCTGCCGGT GGTGTGAGCG CCGTTTCACG 
CAGTCCGGGG ACCTCTACCG CCACGTCCGC AAGTTTCACT GTGGCCTCGT CAAGTCCCTT 
CTGGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ZBTB42 mutation defines a novel lethal congenital contracture syndrome (LCCS6).
Human molecular genetics23(24)6584-93(2014 Dec)
Patel N,Smith LL,Faqeih E,Mohamed J,Gupta VA,Alkuraya FS

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Briefings in bioinformatics12(5)449-62(2011 Sep)
Gaudet P,Livstone MS,Lewis SE,Thomas PD

Characterization of the ZBTB42 gene in humans and mice.
Human genetics129(4)433-41(2011 Apr)
Devaney SA,Mate SE,Devaney JM,Hoffman EP

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ZBTB42 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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