TLR2B cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	TLR2B
Entrez Gene ID	769014
Full Name	toll-like receptor 2 family member B
Synonyms	TLR2,TLR2-2
General protein information	Preferred Names toll-like receptor 2 family member B Names toll-like receptor 2 type-2 Toll-like receptor 2B toll-like receptor 2 type2
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001161650.1	NP_001155122.1	toll-like receptor 2 type-2 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	TLR2	NP_001123941.1
Gallus gallus (chicken)	LOC100858824	XP_004940943.1
Gallus gallus (chicken)	TLR2-2	NP_001155122.1
Gallus gallus (chicken)	TLR2-1	NP_989609.1
Xenopus tropicalis (tropical clawed frog)	LOC100485927	XP_002933538.2
Homo sapiens (human)	TLR2	NP_003255.2
Canis lupus familiaris (dog)	TLR2	NP_001005264.2
Bos taurus (cattle)	TLR2	NP_776622.1
Rattus norvegicus (Norway rat)	Tlr2	NP_942064.1
Xenopus tropicalis (tropical clawed frog)	LOC100485771	XP_002933537.1
Mus musculus (house mouse)	Tlr2	NP_036035.3
Danio rerio (zebrafish)	tlr2	NP_997977.1
	TLR2	NP_001123897.1

Gene Ontology
Bibliography

Related articles in PubMed

Roles of Toll-like receptors 2 and 6 in the inflammatory response to Mycoplasma gallisepticum infection in DF-1 cells and in chicken embryos.
Tian W, Zhao C, Hu Q, Sun J, Peng X
Developmental and comparative immunology5939-47(2016 Jun)

Diacylated lipopeptide from Mycoplasma synoviae mediates TLR15 induced innate immune responses.
Oven I, Resman Rus K, Du?ani? D, Ben?ina D, Keeler CL Jr, Narat M
Veterinary research4499(2013 Oct)

Treatment with ligands for toll-like receptors 2 and 5 induces a mixed T-helper 1- and 2-like response in chicken splenocytes.
St Paul M, Paolucci S, Sharif S
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research32(12)592-8(2012 Dec)

Toll-like receptor 2 type 1 and type 2 polymorphisms in different chicken breeds.
Ruan WK, Wu YH, An J, Cui DF, Li HR, Zheng SJ
Poultry science91(1)101-6(2012 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study was the first to report the differential roles of TLR2-2 and TLR6 in Mycoplasma gallisepticum-infected DF-1 cells and chicken embryos.
Title: Roles of Toll-like receptors 2 and 6 in the inflammatory response to Mycoplasma gallisepticum infection in DF-1 cells and in chicken embryos.

The N-terminal diacylated lipopeptide representing the amino-terminal portion of its mature haemagglutinin protein of Mycoplasma synoviae, significantly induces the expression of TLR15, but not TLR1 and TLR2 in chicken macrophages and chondrocytes.
Title: Diacylated lipopeptide from Mycoplasma synoviae mediates TLR15 induced innate immune responses.

Data suggest that activation of TLR2 induces mixed TH1-/TH2-like response in chicken splenocytes; expression of specific cytokines is up-regulated (TH1-associated interferon-gamma and interleukin-12; TH2-associated interleukin-4).
Title: Treatment with ligands for toll-like receptors 2 and 5 induces a mixed T-helper 1- and 2-like response in chicken splenocytes.

These results demonstrate that ChTLR2 type 1 and type 2 genes are polymorphic among chicken breeds, suggesting a varied resistance among breeds of chicken.
Title: Toll-like receptor 2 type 1 and type 2 polymorphisms in different chicken breeds.

The following TLR2B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TLR2B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa28122	NM_001161650.1 Latest version!	Gallus gallus toll-like receptor 2 family member B (TLR2B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$426.30 $609.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TLR2B ( NM_001161650.1 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_001155122.1 Gallus gallus toll-like receptor 2 family member B (TLR2B), mRNA.

Price & Availability↑

CloneID	OGa28122
Clone ID Related Accession (Same CDS sequence)	NM_001161650.1
Accession Version	NM_001161650.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2199bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-07
Organism	Gallus gallus(chicken)
Product	toll-like receptor 2 type-2 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from FJ915385.1. On Jun 9, 2009 this sequence version replaced XM_001232192.1. ##Evidence-Data-START## Transcript is intronless :: JN544174.1, JN544175.1 [ECO:0000345] ##Evidence-Data-END##

ATGCATACTT GGAAAATGTG GGCAATTTGC ACGGCCTTGG CTGCATACCT CCCTGAAGAA 
CAAGCCCTGA GACAGGCCTG TCTTTCATGC GATGCCACTC AGTCATGCAA CTGCTCTTTC 
ATGGGTTTGG ACTTCATTCC CCCGGGGCTC ACAGGCAAAA TCACGGTGTT AAACCTGGCC 
CATAACAGGA TAAAGGTGAT CCGAACACAT GATCTGCAAA AGGCTGTGAA CCTGAGAACC 
CTGCTGCTGC AGTCCAACCA AATCAGCTCC ATAGATGAGG ACTCGTTTGG CTCTCAGGGG 
AAACTGGAGC TCTTGGACTT GTCAAATAAT AGCCTGGCTC ACTTGTCCCC AGTGTGGTTT 
GGGCCCCTTT TTTCGCTCCA ACACCTTCGC ATTCAAGGCA ATTCCTACAG CGACCTGGGG 
GAAAGTTCCC CCTTTTCCAG CCTGAGAAAC TTGAGCTCCC TCCACCTGGG CAACCCACAG 
TTCTCCATCA TCAGGCAAGG AAACTTTGAG GGCATTGTGT TTCTCAACAC GCTGAGGATT 
GACGGTGACA ATCTCAGTCA GTATGAGCCT GGAAGTCTGA AATCGATCAG GAAGATAAAT 
CACATGATCA TAAGCATAAG AAGGATTGAC GTATTCTCAG CAGTCATCAG GGACCTTCTG 
CACTCTGCCA TTTGGTTAGA TGTAAGAAAA CTAGCATTCA GTGTTCCTGA AAAAATACAA 
CTTTTGAGAA TTATGTCTTC CTCTTTCGCA AAGAAAATTT CTTTAAAACA GTGCTTATTT 
ACAGATGCTA CTGTGCCTGA GATTGTCAGC ATTTTAGAAG GCATGCCAAA ATTAATGGAG 
GTGGAGATGA AAGACTGTAC ACTCTTGGGC ACTGGAAAGT GGTATAAACA AATTCATGCA 
AACCAGTCAC AATCTCTGAG AATTCTGACA ATAGAGAATT TATCTATAGA AGAGTTTTAT 
TTGTTTACAG ATCTTCAGTC TGTACTAGAT CTCCTATCTC TTTTTAGGAA AGTCACAGTT 
GAAAATACCA AGGTGTTTCT GGTGCCATGC AAACTTTCAC AACACCTTCT ATCATTGGAG 
TATCTTGACC TTAGCGCAAA TTTACTTGGA GATCAGAGTT TGGAGCATTC AGCCTGTCAG 
GGTGCATGGC CTTCATTACA AACTCTAAAT CTAAGTCAGA ATTCATTGAG TGACTTAAAA 
ATGACAGGTA AAAGCTTGTT TCATCTAAGA AACCTAAATC TCTTAGACAT CAGTGAAAAC 
AATTTTGGTG AGATTCCAGA CGTGTGTGAA TGGCCTGAAA ACCTGAAATA TCTGAATCTC 
TCCAGCACTC AAATTCCCAA ATTAACAACT TGCATTCCCT CAACTCTTGA AGTGCTGGAC 
GTTAGTGCTA ACAACCTGCA GGATTTTGGA CTGCAACTGC CATTTCTCAA GGAGCTGTAC 
CTGACAAAAA ACCATCTGAA GACCTTGCCT GAAGCCACAG ACATTCCTAA CTTAGTGGCC 
ATGTCGATCA GCAGAAACAA GCTCAACAGC TTCTCCAAGG AAGAGCTGAC AGTGCGAGGG 
GCACAGGTTG GGAGTGTGCA GCTGTCACTG ATGGAGTGCC ACCGGTCCCT CNTAGTGTCC 
TTGATCTGCA CCCTGGTGTT CCTGTTCATC CTCATCCTGG TGGTCGTTGG GTACAAGTAC 
CATGCAGTCT GGTACATGAG AATGACCTGG GCATGGCTCC AAGCCAAGCG GAAGCCCAAG 
CGAGCCCCCA CGAAAGACAT CTGCTACGAC GCTTTTGTCT CCTACAGTGA GAACGACTCC 
AACTGGGTGG AAAACATCAT GGTGCAGCAG CTGGAGCAGG CATGTCCCCC CTTTAGGCTG 
TGCCTCCATA AGCGGGACTT TGTGCCTGGG AAGTGGATTG TGGACAACAT CATTGACTCC 
ATTGAGAAGA GCCACAAGAC GCTCTTTGTG CTATCAGAGC ACTTTGTGCA GAGCGAGTGG 
TGCAAGTATG AGCTGGATTT CTCGCACTTT CGCCTTTTTG ACGAGAACAA CGATGTGGCG 
ATCCTCATCC TGCTGGAGCC CATTCAGAGC CAGGCGATCC CCAAGAGGTT CTGCAAACTG 
CGGAAGATAA TGAACACCAA GACCTACCTG GAGTGGCCTC CTGATGAAGA GCAACAGCAG 
ATGTTTTGGG AAAACTTGAA AGCAGCTCTA AAATCGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001155122.1
CDS	1..2199
Translation	MHTWKMWAICTALAAYLPEEQALRQACLSCDATQSCNCSFMGLDFIPPGLTGKITVLNLAHNRIKVIRTHDLQKAVNLRTLLLQSNQISSIDEDSFGSQGKLELLDLSNNSLAHLSPVWFGPLFSLQHLRIQGNSYSDLGESSPFSSLRNLSSLHLGNPQFSIIRQGNFEGIVFLNTLRIDGDNLSQYEPGSLKSIRKINHMIISIRRIDVFSAVIRDLLHSAIWLDVRKLAFSVPEKIQLLRIMSSSFAKKISLKQCLFTDATVPEIVSILEGMPKLMEVEMKDCTLLGTGKWYKQIHANQSQSLRILTIENLSIEEFYLFTDLQSVLDLLSLFRKVTVENTKVFLVPCKLSQHLLSLEYLDLSANLLGDQSLEHSACQGAWPSLQTLNLSQNSLSDLKMTGKSLFHLRNLNLLDISENNFGEIPDVCEWPENLKYLNLSSTQIPKLTTCIPSTLEVLDVSANNLQDFGLQLPFLKELYLTKNHLKTLPEATDIPNLVAMSISRNKLNSFSKEELTVRGAQVGSVQLSLMECHRSLnullVSLICTLVFLFILILVVVGYKYHAVWYMRMTWAWLQAKRKPKRAPTKDICYDAFVSYSENDSNWVENIMVQQLEQACPPFRLCLHKRDFVPGKWIVDNIIDSIEKSHKTLFVLSEHFVQSEWCKYELDFSHFRLFDENNDVAILILLEPIQSQAIPKRFCKLRKIMNTKTYLEWPPDEEQQQMFWENLKAALKS

Target ORF information:

RefSeq Version	NM_001161650.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus toll-like receptor 2 family member B (TLR2B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001161650.1

ORF Insert Sequence:

ATGCATACTT GGAAAATGTG GGCAATTTGC ACGGCCTTGG CTGCATACCT CCCTGAAGAA 
CAAGCCCTGA GACAGGCCTG TCTTTCATGC GATGCCACTC AGTCATGCAA CTGCTCTTTC 
ATGGGTTTGG ACTTCATTCC CCCGGGGCTC ACAGGCAAAA TCACGGTGTT AAACCTGGCC 
CATAACAGGA TAAAGGTGAT CCGAACACAT GATCTGCAAA AGGCTGTGAA CCTGAGAACC 
CTGCTGCTGC AGTCCAACCA AATCAGCTCC ATAGATGAGG ACTCGTTTGG CTCTCAGGGG 
AAACTGGAGC TCTTGGACTT GTCAAATAAT AGCCTGGCTC ACTTGTCCCC AGTGTGGTTT 
GGGCCCCTTT TTTCGCTCCA ACACCTTCGC ATTCAAGGCA ATTCCTACAG CGACCTGGGG 
GAAAGTTCCC CCTTTTCCAG CCTGAGAAAC TTGAGCTCCC TCCACCTGGG CAACCCACAG 
TTCTCCATCA TCAGGCAAGG AAACTTTGAG GGCATTGTGT TTCTCAACAC GCTGAGGATT 
GACGGTGACA ATCTCAGTCA GTATGAGCCT GGAAGTCTGA AATCGATCAG GAAGATAAAT 
CACATGATCA TAAGCATAAG AAGGATTGAC GTATTCTCAG CAGTCATCAG GGACCTTCTG 
CACTCTGCCA TTTGGTTAGA TGTAAGAAAA CTAGCATTCA GTGTTCCTGA AAAAATACAA 
CTTTTGAGAA TTATGTCTTC CTCTTTCGCA AAGAAAATTT CTTTAAAACA GTGCTTATTT 
ACAGATGCTA CTGTGCCTGA GATTGTCAGC ATTTTAGAAG GCATGCCAAA ATTAATGGAG 
GTGGAGATGA AAGACTGTAC ACTCTTGGGC ACTGGAAAGT GGTATAAACA AATTCATGCA 
AACCAGTCAC AATCTCTGAG AATTCTGACA ATAGAGAATT TATCTATAGA AGAGTTTTAT 
TTGTTTACAG ATCTTCAGTC TGTACTAGAT CTCCTATCTC TTTTTAGGAA AGTCACAGTT 
GAAAATACCA AGGTGTTTCT GGTGCCATGC AAACTTTCAC AACACCTTCT ATCATTGGAG 
TATCTTGACC TTAGCGCAAA TTTACTTGGA GATCAGAGTT TGGAGCATTC AGCCTGTCAG 
GGTGCATGGC CTTCATTACA AACTCTAAAT CTAAGTCAGA ATTCATTGAG TGACTTAAAA 
ATGACAGGTA AAAGCTTGTT TCATCTAAGA AACCTAAATC TCTTAGACAT CAGTGAAAAC 
AATTTTGGTG AGATTCCAGA CGTGTGTGAA TGGCCTGAAA ACCTGAAATA TCTGAATCTC 
TCCAGCACTC AAATTCCCAA ATTAACAACT TGCATTCCCT CAACTCTTGA AGTGCTGGAC 
GTTAGTGCTA ACAACCTGCA GGATTTTGGA CTGCAACTGC CATTTCTCAA GGAGCTGTAC 
CTGACAAAAA ACCATCTGAA GACCTTGCCT GAAGCCACAG ACATTCCTAA CTTAGTGGCC 
ATGTCGATCA GCAGAAACAA GCTCAACAGC TTCTCCAAGG AAGAGCTGAC AGTGCGAGGG 
GCACAGGTTG GGAGTGTGCA GCTGTCACTG ATGGAGTGCC ACCGGTCCCT CNTAGTGTCC 
TTGATCTGCA CCCTGGTGTT CCTGTTCATC CTCATCCTGG TGGTCGTTGG GTACAAGTAC 
CATGCAGTCT GGTACATGAG AATGACCTGG GCATGGCTCC AAGCCAAGCG GAAGCCCAAG 
CGAGCCCCCA CGAAAGACAT CTGCTACGAC GCTTTTGTCT CCTACAGTGA GAACGACTCC 
AACTGGGTGG AAAACATCAT GGTGCAGCAG CTGGAGCAGG CATGTCCCCC CTTTAGGCTG 
TGCCTCCATA AGCGGGACTT TGTGCCTGGG AAGTGGATTG TGGACAACAT CATTGACTCC 
ATTGAGAAGA GCCACAAGAC GCTCTTTGTG CTATCAGAGC ACTTTGTGCA GAGCGAGTGG 
TGCAAGTATG AGCTGGATTT CTCGCACTTT CGCCTTTTTG ACGAGAACAA CGATGTGGCG 
ATCCTCATCC TGCTGGAGCC CATTCAGAGC CAGGCGATCC CCAAGAGGTT CTGCAAACTG 
CGGAAGATAA TGAACACCAA GACCTACCTG GAGTGGCCTC CTGATGAAGA GCAACAGCAG 
ATGTTTTGGG AAAACTTGAA AGCAGCTCTA AAATCGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Roles of Toll-like receptors 2 and 6 in the inflammatory response to Mycoplasma gallisepticum infection in DF-1 cells and in chicken embryos.
Developmental and comparative immunology5939-47(2016 Jun)
Tian W,Zhao C,Hu Q,Sun J,Peng X

Diacylated lipopeptide from Mycoplasma synoviae mediates TLR15 induced innate immune responses.
Veterinary research4499(2013 Oct)
Oven I,Resman Rus K,Du?ani? D,Ben?ina D,Keeler CL Jr,Narat M

Treatment with ligands for toll-like receptors 2 and 5 induces a mixed T-helper 1- and 2-like response in chicken splenocytes.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research32(12)592-8(2012 Dec)
St Paul M,Paolucci S,Sharif S

Toll-like receptor 2 type 1 and type 2 polymorphisms in different chicken breeds.
Poultry science91(1)101-6(2012 Jan)
Ruan WK,Wu YH,An J,Cui DF,Li HR,Zheng SJ

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TLR2B cDNA ORF clone, Gallus gallus(chicken)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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