SYK cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	SYK
Entrez Gene ID	427272
Full Name	spleen associated tyrosine kinase
General protein information	Preferred Names spleen associated tyrosine kinase Names tyrosine-protein kinase SYK spleen tyrosine kinase
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001031430.1	NP_001026601.1	tyrosine-protein kinase SYK
XM_015280297.2	XP_015135783.1	tyrosine-protein kinase SYK isoform X1
XM_015280297.1	XP_015135783.1	tyrosine-protein kinase SYK isoform X1
XM_015280298.1	XP_015135784.1	tyrosine-protein kinase SYK isoform X1
XM_015280298.2	XP_015135784.1	tyrosine-protein kinase SYK isoform X1

Pathways from BioSystems

Homologies

	SYK	XP_001100834.1
Xenopus tropicalis (tropical clawed frog)	syk	XP_002937073.2
Canis lupus familiaris (dog)	SYK	XP_005616010.1
Gallus gallus (chicken)	SYK	NP_001026601.1
Homo sapiens (human)	SYK	NP_001167638.1
Mus musculus (house mouse)	Syk	NP_001185906.1
Pan troglodytes (chimpanzee)	SYK	XP_520123.4
Bos taurus (cattle)	SYK	NP_001032542.1
Rattus norvegicus (Norway rat)	Syk	NP_036890.1
Danio rerio (zebrafish)	syk	NP_998008.1

Gene Ontology
Bibliography

Related articles in PubMed

Nonredundant roles of Src-family kinases and Syk in the initiation of B-cell antigen receptor signaling.
Stepanek O, Draber P, Drobek A, Horejsi V, Brdicka T
Journal of immunology (Baltimore, Md. : 1950)190(4)1807-18(2013 Feb)

The Dok-3/Grb2 protein signal module attenuates Lyn kinase-dependent activation of Syk kinase in B cell antigen receptor microclusters.
L?sing M, Goldbeck I, Manno B, Oellerich T, Schnyder T, Bohnenberger H, Stork B, Urlaub H, Batista FD, Wienands J, Engelke M
The Journal of biological chemistry288(4)2303-13(2013 Jan)

Two closely spaced tyrosines regulate NFAT signaling in B cells via Syk association with Vav.
Chen CH, Martin VA, Gorenstein NM, Geahlen RL, Post CB
Molecular and cellular biology31(14)2984-96(2011 Jul)

Cloning and functional characterization of chicken stem cell antigen 2.
Mao W, Hunt HD, Cheng HH
Developmental and comparative immunology34(3)360-8(2010 Mar)

Generation of an analog-sensitive Syk tyrosine kinase for the study of signaling dynamics from the B cell antigen receptor.
Oh H, Ozkirimli E, Shah K, Harrison ML, Geahlen RL
The Journal of biological chemistry282(46)33760-8(2007 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Analysis of controlled B cell receptor triggering ex vivo and on primary murine B cells reveals that Src family kinases are required for signal initiation and Syk activation.
Title: Nonredundant roles of Src-family kinases and Syk in the initiation of B-cell antigen receptor signaling.

The Dok-3/Grb2 protein signal module attenuates Lyn kinase-dependent activation of Syk kinase in B cell antigen receptor microclusters
Title: The Dok-3/Grb2 protein signal module attenuates Lyn kinase-dependent activation of Syk kinase in B cell antigen receptor microclusters.

Results suggest that the uncommon recognition determinant of two closely spaced tyrosines is a limiting factor in NFAT signaling via Syk association with Vav1.
Title: Two closely spaced tyrosines regulate NFAT signaling in B cells via Syk association with Vav.

Microarray analysis of SCA-2 induced bursal cells showed SYK to be among the under-expressed genes and this was validated with qRT-PCR.
Title: Cloning and functional characterization of chicken stem cell antigen 2.

Syk tyrosine kinase has a role in signaling dynamics of the B cell antigen receptor
Title: Generation of an analog-sensitive Syk tyrosine kinase for the study of signaling dynamics from the B cell antigen receptor.

The following SYK gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SYK cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OGa27847	NM_001031430.1 Latest version!	Gallus gallus spleen associated tyrosine kinase (SYK), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
OGa48070	XM_015280297.2 Latest version!	Gallus gallus spleen associated tyrosine kinase (SYK), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$342.30 $489.00
OGa48070	XM_015280298.2 Latest version!	Gallus gallus spleen associated tyrosine kinase (SYK), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$342.30 $489.00
View Old Accession Versions >>
OGa48070	XM_015280297.1	Gallus gallus spleen tyrosine kinase (SYK), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$342.30 $489.00
OGa48070	XM_015280298.1	Gallus gallus spleen tyrosine kinase (SYK), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$342.30 $489.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SYK ( NM_001031430.1 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_001026601.1 Gallus gallus spleen associated tyrosine kinase (SYK), mRNA.

Price & Availability↑

CloneID	OGa27847
Clone ID Related Accession (Same CDS sequence)	NM_001031430.1
Accession Version	NM_001031430.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1842bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Gallus gallus(chicken)
Product	tyrosine-protein kinase SYK
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ720543.1. On Aug 8, 2005 this sequence version replaced XM_424855.1. ##Evidence-Data-START## Transcript exon combination :: AJ720543.1 [ECO:0000332] ##Evidence-Data-END##

ATGGCTTCCA ACATGGCCAA CCCTGCTAAC CATTTGCCAT ACTTCTTTGG CAATATTACA 
CGTGAGGAAG CTGAGGAGTA TTTGATGCAA GGAGGAATGA GCGATGGACT ATACCTGCTT 
CGCCAAAGCC GGAATTACCT AGGGGGCTTT GCCTTGTCCT TGGCCTATGG AAGGAAGGTT 
CATCATTACA CAATTGAGAG AGAGCTGAGT GGGACATATG CTATTGCAGG AGGCAAATCA 
CATGCAAGTC CTGCTGAACT CATTAACTAT CATTCAGAAG AAGCAGATGG CCTTATCTGT 
CTACTGAGAA AATCTTTCAA TCGACCGCCA GGCGTTGAGC CCAAAACAGG GCCCTTTGAA 
GATTTAAAAG AGAACCTCAT CAGAGAGTAT GTCAAGCAAA CGTGGAATCT GCAGGGTCAT 
GCTCTTGAAC AAGCTATCAT TAGCCAAAAA CCTCAGCTGG AGAAACTGAT TGCTACTACA 
GCCCATGAGA AGATGCCTTG GTTCCATGGG AGGATCTCTC GGGAAGAGTC AGAGCACCGT 
ATCCTCATTG GGTCAAGAAA CGACGGAAAA TTTTTAATAC GAGAAAGGGA CAGCAATGGT 
TCCTATGCCC TGTGTTTGCT CAATGATGGA AAAGTACTGC ATTACCGTAT TGACAGAGAT 
AAGACAGGAA AGCTCTCCAT ACCAGATGGA AAAAGATTTG ACACCCTCTG GCAGTTAGTT 
GAGCATTATT CTTACAAACC GGATGGATTA TTAAGGGTTC TGTCCATTCC CTGTCCACGG 
CATGGCTCAG AAAGTGATAA TGTTGTTTTT GACACTCGTC CTCTCCCTGG AACCCCTTCT 
AAGCTCCAGA CACCTATTGG TGCCCCATCT GATGACCAAA CACCTTTTAA TCCTTATGTA 
CTGCAAAGAG CAAGAGGTCT AATAGGAGCA GAGAAAGGTG ATCAGAGAGA GGCCTTACCC 
ATGGACACTG AGGTTTATGA AAGTCCATAT GCTGATCCAG ATGAAATTAA ACCAAAAAAT 
GTCACTCTCG ACAGGAAATT GTTAACCCTG GAGGAAGGAG AACTTGGCTC TGGAAACTTT 
GGTACTGTAA AGAAAGGGTT CTATAAGATG AAAAAGGGGG CCAAGCCAGT GGCTGTAAAA 
ATTCTTAAGA ACGAGAGCAA TGATCCAGCC ATAAAGGATG AGTTACTGAG AGGAGCAAAT 
GTAATGCAGC AACTGGACAA TCCATATATT GTCCGAATGA TAGGTATATG TGAAGCAGAG 
GCCTGGATGT TAGTAATGGA AATGGCTGAA CTTGGGCCAC TGAACAAGTT TTTGCAAAAA 
AATAGGCACG TCACAGAAAA GAATATAACA GAGCTGGTAC ATCAGGTTTC CATGGGAATG 
AAATATCTGG AGGAGAATAA CTTTGTACAT AGGGATCTGG CTGCAAGGAA CGTGCTATTA 
GTCACCCAGC ATTATGCCAA AATCAGTGAC TTCGGACTAT CTAAGGCTCT TAGTGCTGAT 
GAAAATTATT ACAAGGCACA AAGTCATGGA AAATGGCCAG TCAAGTGGTA TGCTCCAGAA 
TGTATGAATT TCTACAAGTT TTCCAGCAAA AGTGATGTCT GGAGCTTTGG AGTTTTAATG 
TGGGAAGCTT TCTCTTATGG GCAAAAGCCC TATAAAGGAA TGAAAGGTGG TGAAGTTGCA 
CAGATGATTG AAAGAGGAGA ACGAATGGAA TGTCCTGAAG CCTGTCCAGT GGAAGTCTAT 
GACTTAATGA AATTATGTTG GACATACAAT GTTGATGACC GACCAGGATT CGTTGCCGTG 
GAGCTGCGAT TACGGAACTA CTATTACGAC ATTTCCCACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001026601.1
CDS	158..1999
Translation	MASNMANPANHLPYFFGNITREEAEEYLMQGGMSDGLYLLRQSRNYLGGFALSLAYGRKVHHYTIERELSGTYAIAGGKSHASPAELINYHSEEADGLICLLRKSFNRPPGVEPKTGPFEDLKENLIREYVKQTWNLQGHALEQAIISQKPQLEKLIATTAHEKMPWFHGRISREESEHRILIGSRNDGKFLIRERDSNGSYALCLLNDGKVLHYRIDRDKTGKLSIPDGKRFDTLWQLVEHYSYKPDGLLRVLSIPCPRHGSESDNVVFDTRPLPGTPSKLQTPIGAPSDDQTPFNPYVLQRARGLIGAEKGDQREALPMDTEVYESPYADPDEIKPKNVTLDRKLLTLEEGELGSGNFGTVKKGFYKMKKGAKPVAVKILKNESNDPAIKDELLRGANVMQQLDNPYIVRMIGICEAEAWMLVMEMAELGPLNKFLQKNRHVTEKNITELVHQVSMGMKYLEENNFVHRDLAARNVLLVTQHYAKISDFGLSKALSADENYYKAQSHGKWPVKWYAPECMNFYKFSSKSDVWSFGVLMWEAFSYGQKPYKGMKGGEVAQMIERGERMECPEACPVEVYDLMKLCWTYNVDDRPGFVAVELRLRNYYYDISH

Target ORF information:

RefSeq Version	NM_001031430.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus spleen associated tyrosine kinase (SYK), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001031430.1

ORF Insert Sequence:

ATGGCTTCCA ACATGGCCAA CCCTGCTAAC CATTTGCCAT ACTTCTTTGG CAATATTACA 
CGTGAGGAAG CTGAGGAGTA TTTGATGCAA GGAGGAATGA GCGATGGACT ATACCTGCTT 
CGCCAAAGCC GGAATTACCT AGGGGGCTTT GCCTTGTCCT TGGCCTATGG AAGGAAGGTT 
CATCATTACA CAATTGAGAG AGAGCTGAGT GGGACATATG CTATTGCAGG AGGCAAATCA 
CATGCAAGTC CTGCTGAACT CATTAACTAT CATTCAGAAG AAGCAGATGG CCTTATCTGT 
CTACTGAGAA AATCTTTCAA TCGACCGCCA GGCGTTGAGC CCAAAACAGG GCCCTTTGAA 
GATTTAAAAG AGAACCTCAT CAGAGAGTAT GTCAAGCAAA CGTGGAATCT GCAGGGTCAT 
GCTCTTGAAC AAGCTATCAT TAGCCAAAAA CCTCAGCTGG AGAAACTGAT TGCTACTACA 
GCCCATGAGA AGATGCCTTG GTTCCATGGG AGGATCTCTC GGGAAGAGTC AGAGCACCGT 
ATCCTCATTG GGTCAAGAAA CGACGGAAAA TTTTTAATAC GAGAAAGGGA CAGCAATGGT 
TCCTATGCCC TGTGTTTGCT CAATGATGGA AAAGTACTGC ATTACCGTAT TGACAGAGAT 
AAGACAGGAA AGCTCTCCAT ACCAGATGGA AAAAGATTTG ACACCCTCTG GCAGTTAGTT 
GAGCATTATT CTTACAAACC GGATGGATTA TTAAGGGTTC TGTCCATTCC CTGTCCACGG 
CATGGCTCAG AAAGTGATAA TGTTGTTTTT GACACTCGTC CTCTCCCTGG AACCCCTTCT 
AAGCTCCAGA CACCTATTGG TGCCCCATCT GATGACCAAA CACCTTTTAA TCCTTATGTA 
CTGCAAAGAG CAAGAGGTCT AATAGGAGCA GAGAAAGGTG ATCAGAGAGA GGCCTTACCC 
ATGGACACTG AGGTTTATGA AAGTCCATAT GCTGATCCAG ATGAAATTAA ACCAAAAAAT 
GTCACTCTCG ACAGGAAATT GTTAACCCTG GAGGAAGGAG AACTTGGCTC TGGAAACTTT 
GGTACTGTAA AGAAAGGGTT CTATAAGATG AAAAAGGGGG CCAAGCCAGT GGCTGTAAAA 
ATTCTTAAGA ACGAGAGCAA TGATCCAGCC ATAAAGGATG AGTTACTGAG AGGAGCAAAT 
GTAATGCAGC AACTGGACAA TCCATATATT GTCCGAATGA TAGGTATATG TGAAGCAGAG 
GCCTGGATGT TAGTAATGGA AATGGCTGAA CTTGGGCCAC TGAACAAGTT TTTGCAAAAA 
AATAGGCACG TCACAGAAAA GAATATAACA GAGCTGGTAC ATCAGGTTTC CATGGGAATG 
AAATATCTGG AGGAGAATAA CTTTGTACAT AGGGATCTGG CTGCAAGGAA CGTGCTATTA 
GTCACCCAGC ATTATGCCAA AATCAGTGAC TTCGGACTAT CTAAGGCTCT TAGTGCTGAT 
GAAAATTATT ACAAGGCACA AAGTCATGGA AAATGGCCAG TCAAGTGGTA TGCTCCAGAA 
TGTATGAATT TCTACAAGTT TTCCAGCAAA AGTGATGTCT GGAGCTTTGG AGTTTTAATG 
TGGGAAGCTT TCTCTTATGG GCAAAAGCCC TATAAAGGAA TGAAAGGTGG TGAAGTTGCA 
CAGATGATTG AAAGAGGAGA ACGAATGGAA TGTCCTGAAG CCTGTCCAGT GGAAGTCTAT 
GACTTAATGA AATTATGTTG GACATACAAT GTTGATGACC GACCAGGATT CGTTGCCGTG 
GAGCTGCGAT TACGGAACTA CTATTACGAC ATTTCCCACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SYK ( XM_015280297.2 ) cDNA ORF clone, Gallus gallus(chicken) -> XP_015135783.1 Gallus gallus spleen associated tyrosine kinase (SYK), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OGa48070
Clone ID Related Accession (Same CDS sequence)	XM_015280297.2 , XM_015280297.1 , XM_015280298.1 , XM_015280298.2
Accession Version	XM_015280297.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1911bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-16
Organism	Gallus gallus(chicken)
Product	tyrosine-protein kinase SYK isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006127.5) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XM_015280297.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTTCCA ACATGGCCAA CCCTGCTAAC CATTTGCCAT ACTTCTTTGG CAATATTACA 
CGTGAGGAAG CTGAGGAGTA TTTGATGCAA GGAGGAATGA GCGATGGACT ATACCTGCTT 
CGCCAAAGCC GGAATTACCT AGGGGGCTTT GCCTTGTCCT TGGCCTATGG AAGGAAGGTT 
CATCATTACA CAATTGAGAG AGAGCTGAGT GGGACATATG CTATTGCAGG AGGCAAATCA 
CATGCAAGTC CTGCTGAACT CATTAACTAT CATTCAGAAG AAGCAGATGG CCTTATCTGT 
CTACTGAGAA AATCTTTCAA TCGACCGCCA GGCGTTGAGC CCAAAACAGG GCCCTTTGAA 
GATTTAAAAG AGAACCTCAT CAGAGAGTAT GTCAAGCAAA CGTGGAATCT GCAGGGTCAT 
GCTCTTGAAC AAGCTATCAT TAGCCAAAAA CCTCAGCTGG AGAAACTGAT TGCTACTACA 
GCCCATGAGA AGATGCCTTG GTTCCATGGG AGGATCTCTC GGGAAGAGTC AGAGCACCGT 
ATCCTCATTG GGTCAAGAAA CAACGGAAAA TTTTTAATAC GAGAAAGGGA CAGCAATGGT 
TCCTATGCCC TGTGTTTGCT CAATGATGGA AAAGTACTGC ATTACCGTAT TGACAGAGAT 
AAGACAGGAA AGCTCTCCAT ACCAGATGGA AAAAGATTTG ACACCCTCTG GCAGTTAGTT 
GAGCATTATT CTTACAAACC GGATGGATTA TTAAGGGTTC TGTCCATTCC CTGTCCACGG 
CATGGCTCAG AAAGTGATAA TGTTGTTTTT GACACTCGTC CTCTCCCTGG AACCCCTTCT 
AAGAGTTGGG CGAGAGGTGG AATTATCTCA AGACTCAAAT CGTACACCTT TCCAAAGGCT 
GGCAGCAAAA AGCTCCAGAC ACCTATTGGT GCCCCATCTG ATGACCAAAC ACCTTTTAAT 
CCTTATGTAC TGCAAAGAGC AAGAGGTCTA ATAGGAGCAG AGAAAGGTGA TCAGAGAGAG 
GCCTTACCCA TGGACACTGA GGTTTATGAA AGTCCATATG CTGATCCAGA TGAAATTAAA 
CCAAAAAATG TCACTCTCGA CAGGAAATTG TTAACCCTGG AGGAAGGAGA ACTTGGCTCT 
GGAAACTTTG GTACTGTAAA GAAAGGGTTC TATAAGATGA AAAAGGGGGC CAAGCCAGTG 
GCTGTAAAAA TTCTTAAGAA CGAGAGCAAT GATCCAGCCA TAAAGGATGA GTTACTGAGA 
GAAGCAAATG TAATGCAGCA ACTGGACAAT CCATATATTG TCCGAATGAT AGGTATATGT 
GAAGCAGAGG CCTGGATGTT AGTAATGGAA ATGGCTGAAC TTGGGCCACT GAACAAGTTT 
TTGCAAAAAA ATAGGCACGT CACAGAAAAG AATATAACAG AGCTGGTACA TCAGGTTTCC 
ATGGGAATGA AATATCTGGA GGAGAATAAC TTTGTACATA GGGATCTGGC TGCAAGGAAC 
GTGCTATTAG TCACCCAGCA TTATGCCAAA ATCAGTGACT TCGGACTATC TAAGGCTCTT 
AGTGCTGATG AAAATTATTA CAAGGCACAA AGTCATGGAA AATGGCCAGT CAAGTGGTAT 
GCTCCAGAAT GTATGAATTT CTACAAGTTT TCCAGCAAAA GTGATGTCTG GAGCTTTGGA 
GTTTTAATGT GGGAAGCTTT CTCTTATGGG CAAAAGCCCT ATAAAGGAAT GAAAGGTGGT 
GAAGTTGCAC AGATGATTGA AAGAGGAGAA CGAATGGAAT GTCCTGAAGC CTGTCCAGTG 
GAAGTCTATG ACTTAATGAA ATTATGTTGG ACATACAATG TTGATGACCG ACCAGGATTC 
GTTGCCGTGG AGCTGCGATT ACGGAACTAC TATTACGACA TTTCCCACTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_015135783.1
CDS	187..2097
Translation	MASNMANPANHLPYFFGNITREEAEEYLMQGGMSDGLYLLRQSRNYLGGFALSLAYGRKVHHYTIERELSGTYAIAGGKSHASPAELINYHSEEADGLICLLRKSFNRPPGVEPKTGPFEDLKENLIREYVKQTWNLQGHALEQAIISQKPQLEKLIATTAHEKMPWFHGRISREESEHRILIGSRNNGKFLIRERDSNGSYALCLLNDGKVLHYRIDRDKTGKLSIPDGKRFDTLWQLVEHYSYKPDGLLRVLSIPCPRHGSESDNVVFDTRPLPGTPSKSWARGGIISRLKSYTFPKAGSKKLQTPIGAPSDDQTPFNPYVLQRARGLIGAEKGDQREALPMDTEVYESPYADPDEIKPKNVTLDRKLLTLEEGELGSGNFGTVKKGFYKMKKGAKPVAVKILKNESNDPAIKDELLREANVMQQLDNPYIVRMIGICEAEAWMLVMEMAELGPLNKFLQKNRHVTEKNITELVHQVSMGMKYLEENNFVHRDLAARNVLLVTQHYAKISDFGLSKALSADENYYKAQSHGKWPVKWYAPECMNFYKFSSKSDVWSFGVLMWEAFSYGQKPYKGMKGGEVAQMIERGERMECPEACPVEVYDLMKLCWTYNVDDRPGFVAVELRLRNYYYDISH

Target ORF information:

RefSeq Version	XM_015280297.2
Organism	Gallus gallus(chicken)
Definition	Gallus gallus spleen associated tyrosine kinase (SYK), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015280297.2

ORF Insert Sequence:

ATGGCTTCCA ACATGGCCAA CCCTGCTAAC CATTTGCCAT ACTTCTTTGG CAATATTACA 
CGTGAGGAAG CTGAGGAGTA TTTGATGCAA GGAGGAATGA GCGATGGACT ATACCTGCTT 
CGCCAAAGCC GGAATTACCT AGGGGGCTTT GCCTTGTCCT TGGCCTATGG AAGGAAGGTT 
CATCATTACA CAATTGAGAG AGAGCTGAGT GGGACATATG CTATTGCAGG AGGCAAATCA 
CATGCAAGTC CTGCTGAACT CATTAACTAT CATTCAGAAG AAGCAGATGG CCTTATCTGT 
CTACTGAGAA AATCTTTCAA TCGACCGCCA GGCGTTGAGC CCAAAACAGG GCCCTTTGAA 
GATTTAAAAG AGAACCTCAT CAGAGAGTAT GTCAAGCAAA CGTGGAATCT GCAGGGTCAT 
GCTCTTGAAC AAGCTATCAT TAGCCAAAAA CCTCAGCTGG AGAAACTGAT TGCTACTACA 
GCCCATGAGA AGATGCCTTG GTTCCATGGG AGGATCTCTC GGGAAGAGTC AGAGCACCGT 
ATCCTCATTG GGTCAAGAAA CAACGGAAAA TTTTTAATAC GAGAAAGGGA CAGCAATGGT 
TCCTATGCCC TGTGTTTGCT CAATGATGGA AAAGTACTGC ATTACCGTAT TGACAGAGAT 
AAGACAGGAA AGCTCTCCAT ACCAGATGGA AAAAGATTTG ACACCCTCTG GCAGTTAGTT 
GAGCATTATT CTTACAAACC GGATGGATTA TTAAGGGTTC TGTCCATTCC CTGTCCACGG 
CATGGCTCAG AAAGTGATAA TGTTGTTTTT GACACTCGTC CTCTCCCTGG AACCCCTTCT 
AAGAGTTGGG CGAGAGGTGG AATTATCTCA AGACTCAAAT CGTACACCTT TCCAAAGGCT 
GGCAGCAAAA AGCTCCAGAC ACCTATTGGT GCCCCATCTG ATGACCAAAC ACCTTTTAAT 
CCTTATGTAC TGCAAAGAGC AAGAGGTCTA ATAGGAGCAG AGAAAGGTGA TCAGAGAGAG 
GCCTTACCCA TGGACACTGA GGTTTATGAA AGTCCATATG CTGATCCAGA TGAAATTAAA 
CCAAAAAATG TCACTCTCGA CAGGAAATTG TTAACCCTGG AGGAAGGAGA ACTTGGCTCT 
GGAAACTTTG GTACTGTAAA GAAAGGGTTC TATAAGATGA AAAAGGGGGC CAAGCCAGTG 
GCTGTAAAAA TTCTTAAGAA CGAGAGCAAT GATCCAGCCA TAAAGGATGA GTTACTGAGA 
GAAGCAAATG TAATGCAGCA ACTGGACAAT CCATATATTG TCCGAATGAT AGGTATATGT 
GAAGCAGAGG CCTGGATGTT AGTAATGGAA ATGGCTGAAC TTGGGCCACT GAACAAGTTT 
TTGCAAAAAA ATAGGCACGT CACAGAAAAG AATATAACAG AGCTGGTACA TCAGGTTTCC 
ATGGGAATGA AATATCTGGA GGAGAATAAC TTTGTACATA GGGATCTGGC TGCAAGGAAC 
GTGCTATTAG TCACCCAGCA TTATGCCAAA ATCAGTGACT TCGGACTATC TAAGGCTCTT 
AGTGCTGATG AAAATTATTA CAAGGCACAA AGTCATGGAA AATGGCCAGT CAAGTGGTAT 
GCTCCAGAAT GTATGAATTT CTACAAGTTT TCCAGCAAAA GTGATGTCTG GAGCTTTGGA 
GTTTTAATGT GGGAAGCTTT CTCTTATGGG CAAAAGCCCT ATAAAGGAAT GAAAGGTGGT 
GAAGTTGCAC AGATGATTGA AAGAGGAGAA CGAATGGAAT GTCCTGAAGC CTGTCCAGTG 
GAAGTCTATG ACTTAATGAA ATTATGTTGG ACATACAATG TTGATGACCG ACCAGGATTC 
GTTGCCGTGG AGCTGCGATT ACGGAACTAC TATTACGACA TTTCCCACTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SYK ( XM_015280297.1 ) cDNA ORF clone, Gallus gallus(chicken) -> XP_015135783.1 Gallus gallus spleen tyrosine kinase (SYK), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OGa48070
Clone ID Related Accession (Same CDS sequence)	XM_015280297.2 , XM_015280297.1 , XM_015280298.1 , XM_015280298.2
Accession Version	XM_015280297.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1911bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-01-03
Organism	Gallus gallus(chicken)
Product	tyrosine-protein kinase SYK isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003764318.2) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Gallus gallus Annotation Release 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTTCCA ACATGGCCAA CCCTGCTAAC CATTTGCCAT ACTTCTTTGG CAATATTACA 
CGTGAGGAAG CTGAGGAGTA TTTGATGCAA GGAGGAATGA GCGATGGACT ATACCTGCTT 
CGCCAAAGCC GGAATTACCT AGGGGGCTTT GCCTTGTCCT TGGCCTATGG AAGGAAGGTT 
CATCATTACA CAATTGAGAG AGAGCTGAGT GGGACATATG CTATTGCAGG AGGCAAATCA 
CATGCAAGTC CTGCTGAACT CATTAACTAT CATTCAGAAG AAGCAGATGG CCTTATCTGT 
CTACTGAGAA AATCTTTCAA TCGACCGCCA GGCGTTGAGC CCAAAACAGG GCCCTTTGAA 
GATTTAAAAG AGAACCTCAT CAGAGAGTAT GTCAAGCAAA CGTGGAATCT GCAGGGTCAT 
GCTCTTGAAC AAGCTATCAT TAGCCAAAAA CCTCAGCTGG AGAAACTGAT TGCTACTACA 
GCCCATGAGA AGATGCCTTG GTTCCATGGG AGGATCTCTC GGGAAGAGTC AGAGCACCGT 
ATCCTCATTG GGTCAAGAAA CAACGGAAAA TTTTTAATAC GAGAAAGGGA CAGCAATGGT 
TCCTATGCCC TGTGTTTGCT CAATGATGGA AAAGTACTGC ATTACCGTAT TGACAGAGAT 
AAGACAGGAA AGCTCTCCAT ACCAGATGGA AAAAGATTTG ACACCCTCTG GCAGTTAGTT 
GAGCATTATT CTTACAAACC GGATGGATTA TTAAGGGTTC TGTCCATTCC CTGTCCACGG 
CATGGCTCAG AAAGTGATAA TGTTGTTTTT GACACTCGTC CTCTCCCTGG AACCCCTTCT 
AAGAGTTGGG CGAGAGGTGG AATTATCTCA AGACTCAAAT CGTACACCTT TCCAAAGGCT 
GGCAGCAAAA AGCTCCAGAC ACCTATTGGT GCCCCATCTG ATGACCAAAC ACCTTTTAAT 
CCTTATGTAC TGCAAAGAGC AAGAGGTCTA ATAGGAGCAG AGAAAGGTGA TCAGAGAGAG 
GCCTTACCCA TGGACACTGA GGTTTATGAA AGTCCATATG CTGATCCAGA TGAAATTAAA 
CCAAAAAATG TCACTCTCGA CAGGAAATTG TTAACCCTGG AGGAAGGAGA ACTTGGCTCT 
GGAAACTTTG GTACTGTAAA GAAAGGGTTC TATAAGATGA AAAAGGGGGC CAAGCCAGTG 
GCTGTAAAAA TTCTTAAGAA CGAGAGCAAT GATCCAGCCA TAAAGGATGA GTTACTGAGA 
GAAGCAAATG TAATGCAGCA ACTGGACAAT CCATATATTG TCCGAATGAT AGGTATATGT 
GAAGCAGAGG CCTGGATGTT AGTAATGGAA ATGGCTGAAC TTGGGCCACT GAACAAGTTT 
TTGCAAAAAA ATAGGCACGT CACAGAAAAG AATATAACAG AGCTGGTACA TCAGGTTTCC 
ATGGGAATGA AATATCTGGA GGAGAATAAC TTTGTACATA GGGATCTGGC TGCAAGGAAC 
GTGCTATTAG TCACCCAGCA TTATGCCAAA ATCAGTGACT TCGGACTATC TAAGGCTCTT 
AGTGCTGATG AAAATTATTA CAAGGCACAA AGTCATGGAA AATGGCCAGT CAAGTGGTAT 
GCTCCAGAAT GTATGAATTT CTACAAGTTT TCCAGCAAAA GTGATGTCTG GAGCTTTGGA 
GTTTTAATGT GGGAAGCTTT CTCTTATGGG CAAAAGCCCT ATAAAGGAAT GAAAGGTGGT 
GAAGTTGCAC AGATGATTGA AAGAGGAGAA CGAATGGAAT GTCCTGAAGC CTGTCCAGTG 
GAAGTCTATG ACTTAATGAA ATTATGTTGG ACATACAATG TTGATGACCG ACCAGGATTC 
GTTGCCGTGG AGCTGCGATT ACGGAACTAC TATTACGACA TTTCCCACTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_015135783.1
CDS	1558..3468
Translation	MASNMANPANHLPYFFGNITREEAEEYLMQGGMSDGLYLLRQSRNYLGGFALSLAYGRKVHHYTIERELSGTYAIAGGKSHASPAELINYHSEEADGLICLLRKSFNRPPGVEPKTGPFEDLKENLIREYVKQTWNLQGHALEQAIISQKPQLEKLIATTAHEKMPWFHGRISREESEHRILIGSRNNGKFLIRERDSNGSYALCLLNDGKVLHYRIDRDKTGKLSIPDGKRFDTLWQLVEHYSYKPDGLLRVLSIPCPRHGSESDNVVFDTRPLPGTPSKSWARGGIISRLKSYTFPKAGSKKLQTPIGAPSDDQTPFNPYVLQRARGLIGAEKGDQREALPMDTEVYESPYADPDEIKPKNVTLDRKLLTLEEGELGSGNFGTVKKGFYKMKKGAKPVAVKILKNESNDPAIKDELLREANVMQQLDNPYIVRMIGICEAEAWMLVMEMAELGPLNKFLQKNRHVTEKNITELVHQVSMGMKYLEENNFVHRDLAARNVLLVTQHYAKISDFGLSKALSADENYYKAQSHGKWPVKWYAPECMNFYKFSSKSDVWSFGVLMWEAFSYGQKPYKGMKGGEVAQMIERGERMECPEACPVEVYDLMKLCWTYNVDDRPGFVAVELRLRNYYYDISH

Target ORF information:

RefSeq Version	XM_015280297.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus spleen tyrosine kinase (SYK), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015280297.1

ORF Insert Sequence:

ATGGCTTCCA ACATGGCCAA CCCTGCTAAC CATTTGCCAT ACTTCTTTGG CAATATTACA 
CGTGAGGAAG CTGAGGAGTA TTTGATGCAA GGAGGAATGA GCGATGGACT ATACCTGCTT 
CGCCAAAGCC GGAATTACCT AGGGGGCTTT GCCTTGTCCT TGGCCTATGG AAGGAAGGTT 
CATCATTACA CAATTGAGAG AGAGCTGAGT GGGACATATG CTATTGCAGG AGGCAAATCA 
CATGCAAGTC CTGCTGAACT CATTAACTAT CATTCAGAAG AAGCAGATGG CCTTATCTGT 
CTACTGAGAA AATCTTTCAA TCGACCGCCA GGCGTTGAGC CCAAAACAGG GCCCTTTGAA 
GATTTAAAAG AGAACCTCAT CAGAGAGTAT GTCAAGCAAA CGTGGAATCT GCAGGGTCAT 
GCTCTTGAAC AAGCTATCAT TAGCCAAAAA CCTCAGCTGG AGAAACTGAT TGCTACTACA 
GCCCATGAGA AGATGCCTTG GTTCCATGGG AGGATCTCTC GGGAAGAGTC AGAGCACCGT 
ATCCTCATTG GGTCAAGAAA CAACGGAAAA TTTTTAATAC GAGAAAGGGA CAGCAATGGT 
TCCTATGCCC TGTGTTTGCT CAATGATGGA AAAGTACTGC ATTACCGTAT TGACAGAGAT 
AAGACAGGAA AGCTCTCCAT ACCAGATGGA AAAAGATTTG ACACCCTCTG GCAGTTAGTT 
GAGCATTATT CTTACAAACC GGATGGATTA TTAAGGGTTC TGTCCATTCC CTGTCCACGG 
CATGGCTCAG AAAGTGATAA TGTTGTTTTT GACACTCGTC CTCTCCCTGG AACCCCTTCT 
AAGAGTTGGG CGAGAGGTGG AATTATCTCA AGACTCAAAT CGTACACCTT TCCAAAGGCT 
GGCAGCAAAA AGCTCCAGAC ACCTATTGGT GCCCCATCTG ATGACCAAAC ACCTTTTAAT 
CCTTATGTAC TGCAAAGAGC AAGAGGTCTA ATAGGAGCAG AGAAAGGTGA TCAGAGAGAG 
GCCTTACCCA TGGACACTGA GGTTTATGAA AGTCCATATG CTGATCCAGA TGAAATTAAA 
CCAAAAAATG TCACTCTCGA CAGGAAATTG TTAACCCTGG AGGAAGGAGA ACTTGGCTCT 
GGAAACTTTG GTACTGTAAA GAAAGGGTTC TATAAGATGA AAAAGGGGGC CAAGCCAGTG 
GCTGTAAAAA TTCTTAAGAA CGAGAGCAAT GATCCAGCCA TAAAGGATGA GTTACTGAGA 
GAAGCAAATG TAATGCAGCA ACTGGACAAT CCATATATTG TCCGAATGAT AGGTATATGT 
GAAGCAGAGG CCTGGATGTT AGTAATGGAA ATGGCTGAAC TTGGGCCACT GAACAAGTTT 
TTGCAAAAAA ATAGGCACGT CACAGAAAAG AATATAACAG AGCTGGTACA TCAGGTTTCC 
ATGGGAATGA AATATCTGGA GGAGAATAAC TTTGTACATA GGGATCTGGC TGCAAGGAAC 
GTGCTATTAG TCACCCAGCA TTATGCCAAA ATCAGTGACT TCGGACTATC TAAGGCTCTT 
AGTGCTGATG AAAATTATTA CAAGGCACAA AGTCATGGAA AATGGCCAGT CAAGTGGTAT 
GCTCCAGAAT GTATGAATTT CTACAAGTTT TCCAGCAAAA GTGATGTCTG GAGCTTTGGA 
GTTTTAATGT GGGAAGCTTT CTCTTATGGG CAAAAGCCCT ATAAAGGAAT GAAAGGTGGT 
GAAGTTGCAC AGATGATTGA AAGAGGAGAA CGAATGGAAT GTCCTGAAGC CTGTCCAGTG 
GAAGTCTATG ACTTAATGAA ATTATGTTGG ACATACAATG TTGATGACCG ACCAGGATTC 
GTTGCCGTGG AGCTGCGATT ACGGAACTAC TATTACGACA TTTCCCACTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SYK ( XM_015280298.1 ) cDNA ORF clone, Gallus gallus(chicken) -> XP_015135784.1 Gallus gallus spleen tyrosine kinase (SYK), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OGa48070
Clone ID Related Accession (Same CDS sequence)	XM_015280297.2 , XM_015280297.1 , XM_015280298.1 , XM_015280298.2
Accession Version	XM_015280298.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1911bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-01-03
Organism	Gallus gallus(chicken)
Product	tyrosine-protein kinase SYK isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003764318.2) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Gallus gallus Annotation Release 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTTCCA ACATGGCCAA CCCTGCTAAC CATTTGCCAT ACTTCTTTGG CAATATTACA 
CGTGAGGAAG CTGAGGAGTA TTTGATGCAA GGAGGAATGA GCGATGGACT ATACCTGCTT 
CGCCAAAGCC GGAATTACCT AGGGGGCTTT GCCTTGTCCT TGGCCTATGG AAGGAAGGTT 
CATCATTACA CAATTGAGAG AGAGCTGAGT GGGACATATG CTATTGCAGG AGGCAAATCA 
CATGCAAGTC CTGCTGAACT CATTAACTAT CATTCAGAAG AAGCAGATGG CCTTATCTGT 
CTACTGAGAA AATCTTTCAA TCGACCGCCA GGCGTTGAGC CCAAAACAGG GCCCTTTGAA 
GATTTAAAAG AGAACCTCAT CAGAGAGTAT GTCAAGCAAA CGTGGAATCT GCAGGGTCAT 
GCTCTTGAAC AAGCTATCAT TAGCCAAAAA CCTCAGCTGG AGAAACTGAT TGCTACTACA 
GCCCATGAGA AGATGCCTTG GTTCCATGGG AGGATCTCTC GGGAAGAGTC AGAGCACCGT 
ATCCTCATTG GGTCAAGAAA CAACGGAAAA TTTTTAATAC GAGAAAGGGA CAGCAATGGT 
TCCTATGCCC TGTGTTTGCT CAATGATGGA AAAGTACTGC ATTACCGTAT TGACAGAGAT 
AAGACAGGAA AGCTCTCCAT ACCAGATGGA AAAAGATTTG ACACCCTCTG GCAGTTAGTT 
GAGCATTATT CTTACAAACC GGATGGATTA TTAAGGGTTC TGTCCATTCC CTGTCCACGG 
CATGGCTCAG AAAGTGATAA TGTTGTTTTT GACACTCGTC CTCTCCCTGG AACCCCTTCT 
AAGAGTTGGG CGAGAGGTGG AATTATCTCA AGACTCAAAT CGTACACCTT TCCAAAGGCT 
GGCAGCAAAA AGCTCCAGAC ACCTATTGGT GCCCCATCTG ATGACCAAAC ACCTTTTAAT 
CCTTATGTAC TGCAAAGAGC AAGAGGTCTA ATAGGAGCAG AGAAAGGTGA TCAGAGAGAG 
GCCTTACCCA TGGACACTGA GGTTTATGAA AGTCCATATG CTGATCCAGA TGAAATTAAA 
CCAAAAAATG TCACTCTCGA CAGGAAATTG TTAACCCTGG AGGAAGGAGA ACTTGGCTCT 
GGAAACTTTG GTACTGTAAA GAAAGGGTTC TATAAGATGA AAAAGGGGGC CAAGCCAGTG 
GCTGTAAAAA TTCTTAAGAA CGAGAGCAAT GATCCAGCCA TAAAGGATGA GTTACTGAGA 
GAAGCAAATG TAATGCAGCA ACTGGACAAT CCATATATTG TCCGAATGAT AGGTATATGT 
GAAGCAGAGG CCTGGATGTT AGTAATGGAA ATGGCTGAAC TTGGGCCACT GAACAAGTTT 
TTGCAAAAAA ATAGGCACGT CACAGAAAAG AATATAACAG AGCTGGTACA TCAGGTTTCC 
ATGGGAATGA AATATCTGGA GGAGAATAAC TTTGTACATA GGGATCTGGC TGCAAGGAAC 
GTGCTATTAG TCACCCAGCA TTATGCCAAA ATCAGTGACT TCGGACTATC TAAGGCTCTT 
AGTGCTGATG AAAATTATTA CAAGGCACAA AGTCATGGAA AATGGCCAGT CAAGTGGTAT 
GCTCCAGAAT GTATGAATTT CTACAAGTTT TCCAGCAAAA GTGATGTCTG GAGCTTTGGA 
GTTTTAATGT GGGAAGCTTT CTCTTATGGG CAAAAGCCCT ATAAAGGAAT GAAAGGTGGT 
GAAGTTGCAC AGATGATTGA AAGAGGAGAA CGAATGGAAT GTCCTGAAGC CTGTCCAGTG 
GAAGTCTATG ACTTAATGAA ATTATGTTGG ACATACAATG TTGATGACCG ACCAGGATTC 
GTTGCCGTGG AGCTGCGATT ACGGAACTAC TATTACGACA TTTCCCACTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_015135784.1
CDS	320..2230
Translation	MASNMANPANHLPYFFGNITREEAEEYLMQGGMSDGLYLLRQSRNYLGGFALSLAYGRKVHHYTIERELSGTYAIAGGKSHASPAELINYHSEEADGLICLLRKSFNRPPGVEPKTGPFEDLKENLIREYVKQTWNLQGHALEQAIISQKPQLEKLIATTAHEKMPWFHGRISREESEHRILIGSRNNGKFLIRERDSNGSYALCLLNDGKVLHYRIDRDKTGKLSIPDGKRFDTLWQLVEHYSYKPDGLLRVLSIPCPRHGSESDNVVFDTRPLPGTPSKSWARGGIISRLKSYTFPKAGSKKLQTPIGAPSDDQTPFNPYVLQRARGLIGAEKGDQREALPMDTEVYESPYADPDEIKPKNVTLDRKLLTLEEGELGSGNFGTVKKGFYKMKKGAKPVAVKILKNESNDPAIKDELLREANVMQQLDNPYIVRMIGICEAEAWMLVMEMAELGPLNKFLQKNRHVTEKNITELVHQVSMGMKYLEENNFVHRDLAARNVLLVTQHYAKISDFGLSKALSADENYYKAQSHGKWPVKWYAPECMNFYKFSSKSDVWSFGVLMWEAFSYGQKPYKGMKGGEVAQMIERGERMECPEACPVEVYDLMKLCWTYNVDDRPGFVAVELRLRNYYYDISH

Target ORF information:

RefSeq Version	XM_015280298.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus spleen tyrosine kinase (SYK), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015280298.1

ORF Insert Sequence:

ATGGCTTCCA ACATGGCCAA CCCTGCTAAC CATTTGCCAT ACTTCTTTGG CAATATTACA 
CGTGAGGAAG CTGAGGAGTA TTTGATGCAA GGAGGAATGA GCGATGGACT ATACCTGCTT 
CGCCAAAGCC GGAATTACCT AGGGGGCTTT GCCTTGTCCT TGGCCTATGG AAGGAAGGTT 
CATCATTACA CAATTGAGAG AGAGCTGAGT GGGACATATG CTATTGCAGG AGGCAAATCA 
CATGCAAGTC CTGCTGAACT CATTAACTAT CATTCAGAAG AAGCAGATGG CCTTATCTGT 
CTACTGAGAA AATCTTTCAA TCGACCGCCA GGCGTTGAGC CCAAAACAGG GCCCTTTGAA 
GATTTAAAAG AGAACCTCAT CAGAGAGTAT GTCAAGCAAA CGTGGAATCT GCAGGGTCAT 
GCTCTTGAAC AAGCTATCAT TAGCCAAAAA CCTCAGCTGG AGAAACTGAT TGCTACTACA 
GCCCATGAGA AGATGCCTTG GTTCCATGGG AGGATCTCTC GGGAAGAGTC AGAGCACCGT 
ATCCTCATTG GGTCAAGAAA CAACGGAAAA TTTTTAATAC GAGAAAGGGA CAGCAATGGT 
TCCTATGCCC TGTGTTTGCT CAATGATGGA AAAGTACTGC ATTACCGTAT TGACAGAGAT 
AAGACAGGAA AGCTCTCCAT ACCAGATGGA AAAAGATTTG ACACCCTCTG GCAGTTAGTT 
GAGCATTATT CTTACAAACC GGATGGATTA TTAAGGGTTC TGTCCATTCC CTGTCCACGG 
CATGGCTCAG AAAGTGATAA TGTTGTTTTT GACACTCGTC CTCTCCCTGG AACCCCTTCT 
AAGAGTTGGG CGAGAGGTGG AATTATCTCA AGACTCAAAT CGTACACCTT TCCAAAGGCT 
GGCAGCAAAA AGCTCCAGAC ACCTATTGGT GCCCCATCTG ATGACCAAAC ACCTTTTAAT 
CCTTATGTAC TGCAAAGAGC AAGAGGTCTA ATAGGAGCAG AGAAAGGTGA TCAGAGAGAG 
GCCTTACCCA TGGACACTGA GGTTTATGAA AGTCCATATG CTGATCCAGA TGAAATTAAA 
CCAAAAAATG TCACTCTCGA CAGGAAATTG TTAACCCTGG AGGAAGGAGA ACTTGGCTCT 
GGAAACTTTG GTACTGTAAA GAAAGGGTTC TATAAGATGA AAAAGGGGGC CAAGCCAGTG 
GCTGTAAAAA TTCTTAAGAA CGAGAGCAAT GATCCAGCCA TAAAGGATGA GTTACTGAGA 
GAAGCAAATG TAATGCAGCA ACTGGACAAT CCATATATTG TCCGAATGAT AGGTATATGT 
GAAGCAGAGG CCTGGATGTT AGTAATGGAA ATGGCTGAAC TTGGGCCACT GAACAAGTTT 
TTGCAAAAAA ATAGGCACGT CACAGAAAAG AATATAACAG AGCTGGTACA TCAGGTTTCC 
ATGGGAATGA AATATCTGGA GGAGAATAAC TTTGTACATA GGGATCTGGC TGCAAGGAAC 
GTGCTATTAG TCACCCAGCA TTATGCCAAA ATCAGTGACT TCGGACTATC TAAGGCTCTT 
AGTGCTGATG AAAATTATTA CAAGGCACAA AGTCATGGAA AATGGCCAGT CAAGTGGTAT 
GCTCCAGAAT GTATGAATTT CTACAAGTTT TCCAGCAAAA GTGATGTCTG GAGCTTTGGA 
GTTTTAATGT GGGAAGCTTT CTCTTATGGG CAAAAGCCCT ATAAAGGAAT GAAAGGTGGT 
GAAGTTGCAC AGATGATTGA AAGAGGAGAA CGAATGGAAT GTCCTGAAGC CTGTCCAGTG 
GAAGTCTATG ACTTAATGAA ATTATGTTGG ACATACAATG TTGATGACCG ACCAGGATTC 
GTTGCCGTGG AGCTGCGATT ACGGAACTAC TATTACGACA TTTCCCACTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SYK ( XM_015280298.2 ) cDNA ORF clone, Gallus gallus(chicken) -> XP_015135784.1 Gallus gallus spleen associated tyrosine kinase (SYK), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OGa48070
Clone ID Related Accession (Same CDS sequence)	XM_015280297.2 , XM_015280297.1 , XM_015280298.1 , XM_015280298.2
Accession Version	XM_015280298.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1911bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-16
Organism	Gallus gallus(chicken)
Product	tyrosine-protein kinase SYK isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006127.5) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XM_015280298.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTTCCA ACATGGCCAA CCCTGCTAAC CATTTGCCAT ACTTCTTTGG CAATATTACA 
CGTGAGGAAG CTGAGGAGTA TTTGATGCAA GGAGGAATGA GCGATGGACT ATACCTGCTT 
CGCCAAAGCC GGAATTACCT AGGGGGCTTT GCCTTGTCCT TGGCCTATGG AAGGAAGGTT 
CATCATTACA CAATTGAGAG AGAGCTGAGT GGGACATATG CTATTGCAGG AGGCAAATCA 
CATGCAAGTC CTGCTGAACT CATTAACTAT CATTCAGAAG AAGCAGATGG CCTTATCTGT 
CTACTGAGAA AATCTTTCAA TCGACCGCCA GGCGTTGAGC CCAAAACAGG GCCCTTTGAA 
GATTTAAAAG AGAACCTCAT CAGAGAGTAT GTCAAGCAAA CGTGGAATCT GCAGGGTCAT 
GCTCTTGAAC AAGCTATCAT TAGCCAAAAA CCTCAGCTGG AGAAACTGAT TGCTACTACA 
GCCCATGAGA AGATGCCTTG GTTCCATGGG AGGATCTCTC GGGAAGAGTC AGAGCACCGT 
ATCCTCATTG GGTCAAGAAA CAACGGAAAA TTTTTAATAC GAGAAAGGGA CAGCAATGGT 
TCCTATGCCC TGTGTTTGCT CAATGATGGA AAAGTACTGC ATTACCGTAT TGACAGAGAT 
AAGACAGGAA AGCTCTCCAT ACCAGATGGA AAAAGATTTG ACACCCTCTG GCAGTTAGTT 
GAGCATTATT CTTACAAACC GGATGGATTA TTAAGGGTTC TGTCCATTCC CTGTCCACGG 
CATGGCTCAG AAAGTGATAA TGTTGTTTTT GACACTCGTC CTCTCCCTGG AACCCCTTCT 
AAGAGTTGGG CGAGAGGTGG AATTATCTCA AGACTCAAAT CGTACACCTT TCCAAAGGCT 
GGCAGCAAAA AGCTCCAGAC ACCTATTGGT GCCCCATCTG ATGACCAAAC ACCTTTTAAT 
CCTTATGTAC TGCAAAGAGC AAGAGGTCTA ATAGGAGCAG AGAAAGGTGA TCAGAGAGAG 
GCCTTACCCA TGGACACTGA GGTTTATGAA AGTCCATATG CTGATCCAGA TGAAATTAAA 
CCAAAAAATG TCACTCTCGA CAGGAAATTG TTAACCCTGG AGGAAGGAGA ACTTGGCTCT 
GGAAACTTTG GTACTGTAAA GAAAGGGTTC TATAAGATGA AAAAGGGGGC CAAGCCAGTG 
GCTGTAAAAA TTCTTAAGAA CGAGAGCAAT GATCCAGCCA TAAAGGATGA GTTACTGAGA 
GAAGCAAATG TAATGCAGCA ACTGGACAAT CCATATATTG TCCGAATGAT AGGTATATGT 
GAAGCAGAGG CCTGGATGTT AGTAATGGAA ATGGCTGAAC TTGGGCCACT GAACAAGTTT 
TTGCAAAAAA ATAGGCACGT CACAGAAAAG AATATAACAG AGCTGGTACA TCAGGTTTCC 
ATGGGAATGA AATATCTGGA GGAGAATAAC TTTGTACATA GGGATCTGGC TGCAAGGAAC 
GTGCTATTAG TCACCCAGCA TTATGCCAAA ATCAGTGACT TCGGACTATC TAAGGCTCTT 
AGTGCTGATG AAAATTATTA CAAGGCACAA AGTCATGGAA AATGGCCAGT CAAGTGGTAT 
GCTCCAGAAT GTATGAATTT CTACAAGTTT TCCAGCAAAA GTGATGTCTG GAGCTTTGGA 
GTTTTAATGT GGGAAGCTTT CTCTTATGGG CAAAAGCCCT ATAAAGGAAT GAAAGGTGGT 
GAAGTTGCAC AGATGATTGA AAGAGGAGAA CGAATGGAAT GTCCTGAAGC CTGTCCAGTG 
GAAGTCTATG ACTTAATGAA ATTATGTTGG ACATACAATG TTGATGACCG ACCAGGATTC 
GTTGCCGTGG AGCTGCGATT ACGGAACTAC TATTACGACA TTTCCCACTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_015135784.1
CDS	145..2055
Translation	MASNMANPANHLPYFFGNITREEAEEYLMQGGMSDGLYLLRQSRNYLGGFALSLAYGRKVHHYTIERELSGTYAIAGGKSHASPAELINYHSEEADGLICLLRKSFNRPPGVEPKTGPFEDLKENLIREYVKQTWNLQGHALEQAIISQKPQLEKLIATTAHEKMPWFHGRISREESEHRILIGSRNNGKFLIRERDSNGSYALCLLNDGKVLHYRIDRDKTGKLSIPDGKRFDTLWQLVEHYSYKPDGLLRVLSIPCPRHGSESDNVVFDTRPLPGTPSKSWARGGIISRLKSYTFPKAGSKKLQTPIGAPSDDQTPFNPYVLQRARGLIGAEKGDQREALPMDTEVYESPYADPDEIKPKNVTLDRKLLTLEEGELGSGNFGTVKKGFYKMKKGAKPVAVKILKNESNDPAIKDELLREANVMQQLDNPYIVRMIGICEAEAWMLVMEMAELGPLNKFLQKNRHVTEKNITELVHQVSMGMKYLEENNFVHRDLAARNVLLVTQHYAKISDFGLSKALSADENYYKAQSHGKWPVKWYAPECMNFYKFSSKSDVWSFGVLMWEAFSYGQKPYKGMKGGEVAQMIERGERMECPEACPVEVYDLMKLCWTYNVDDRPGFVAVELRLRNYYYDISH

Target ORF information:

RefSeq Version	XM_015280298.2
Organism	Gallus gallus(chicken)
Definition	Gallus gallus spleen associated tyrosine kinase (SYK), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_015280298.2

ORF Insert Sequence:

ATGGCTTCCA ACATGGCCAA CCCTGCTAAC CATTTGCCAT ACTTCTTTGG CAATATTACA 
CGTGAGGAAG CTGAGGAGTA TTTGATGCAA GGAGGAATGA GCGATGGACT ATACCTGCTT 
CGCCAAAGCC GGAATTACCT AGGGGGCTTT GCCTTGTCCT TGGCCTATGG AAGGAAGGTT 
CATCATTACA CAATTGAGAG AGAGCTGAGT GGGACATATG CTATTGCAGG AGGCAAATCA 
CATGCAAGTC CTGCTGAACT CATTAACTAT CATTCAGAAG AAGCAGATGG CCTTATCTGT 
CTACTGAGAA AATCTTTCAA TCGACCGCCA GGCGTTGAGC CCAAAACAGG GCCCTTTGAA 
GATTTAAAAG AGAACCTCAT CAGAGAGTAT GTCAAGCAAA CGTGGAATCT GCAGGGTCAT 
GCTCTTGAAC AAGCTATCAT TAGCCAAAAA CCTCAGCTGG AGAAACTGAT TGCTACTACA 
GCCCATGAGA AGATGCCTTG GTTCCATGGG AGGATCTCTC GGGAAGAGTC AGAGCACCGT 
ATCCTCATTG GGTCAAGAAA CAACGGAAAA TTTTTAATAC GAGAAAGGGA CAGCAATGGT 
TCCTATGCCC TGTGTTTGCT CAATGATGGA AAAGTACTGC ATTACCGTAT TGACAGAGAT 
AAGACAGGAA AGCTCTCCAT ACCAGATGGA AAAAGATTTG ACACCCTCTG GCAGTTAGTT 
GAGCATTATT CTTACAAACC GGATGGATTA TTAAGGGTTC TGTCCATTCC CTGTCCACGG 
CATGGCTCAG AAAGTGATAA TGTTGTTTTT GACACTCGTC CTCTCCCTGG AACCCCTTCT 
AAGAGTTGGG CGAGAGGTGG AATTATCTCA AGACTCAAAT CGTACACCTT TCCAAAGGCT 
GGCAGCAAAA AGCTCCAGAC ACCTATTGGT GCCCCATCTG ATGACCAAAC ACCTTTTAAT 
CCTTATGTAC TGCAAAGAGC AAGAGGTCTA ATAGGAGCAG AGAAAGGTGA TCAGAGAGAG 
GCCTTACCCA TGGACACTGA GGTTTATGAA AGTCCATATG CTGATCCAGA TGAAATTAAA 
CCAAAAAATG TCACTCTCGA CAGGAAATTG TTAACCCTGG AGGAAGGAGA ACTTGGCTCT 
GGAAACTTTG GTACTGTAAA GAAAGGGTTC TATAAGATGA AAAAGGGGGC CAAGCCAGTG 
GCTGTAAAAA TTCTTAAGAA CGAGAGCAAT GATCCAGCCA TAAAGGATGA GTTACTGAGA 
GAAGCAAATG TAATGCAGCA ACTGGACAAT CCATATATTG TCCGAATGAT AGGTATATGT 
GAAGCAGAGG CCTGGATGTT AGTAATGGAA ATGGCTGAAC TTGGGCCACT GAACAAGTTT 
TTGCAAAAAA ATAGGCACGT CACAGAAAAG AATATAACAG AGCTGGTACA TCAGGTTTCC 
ATGGGAATGA AATATCTGGA GGAGAATAAC TTTGTACATA GGGATCTGGC TGCAAGGAAC 
GTGCTATTAG TCACCCAGCA TTATGCCAAA ATCAGTGACT TCGGACTATC TAAGGCTCTT 
AGTGCTGATG AAAATTATTA CAAGGCACAA AGTCATGGAA AATGGCCAGT CAAGTGGTAT 
GCTCCAGAAT GTATGAATTT CTACAAGTTT TCCAGCAAAA GTGATGTCTG GAGCTTTGGA 
GTTTTAATGT GGGAAGCTTT CTCTTATGGG CAAAAGCCCT ATAAAGGAAT GAAAGGTGGT 
GAAGTTGCAC AGATGATTGA AAGAGGAGAA CGAATGGAAT GTCCTGAAGC CTGTCCAGTG 
GAAGTCTATG ACTTAATGAA ATTATGTTGG ACATACAATG TTGATGACCG ACCAGGATTC 
GTTGCCGTGG AGCTGCGATT ACGGAACTAC TATTACGACA TTTCCCACTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Nonredundant roles of Src-family kinases and Syk in the initiation of B-cell antigen receptor signaling.
Journal of immunology (Baltimore, Md. : 1950)190(4)1807-18(2013 Feb)
Stepanek O,Draber P,Drobek A,Horejsi V,Brdicka T

The Dok-3/Grb2 protein signal module attenuates Lyn kinase-dependent activation of Syk kinase in B cell antigen receptor microclusters.
The Journal of biological chemistry288(4)2303-13(2013 Jan)
L?sing M,Goldbeck I,Manno B,Oellerich T,Schnyder T,Bohnenberger H,Stork B,Urlaub H,Batista FD,Wienands J,Engelke M

Two closely spaced tyrosines regulate NFAT signaling in B cells via Syk association with Vav.
Molecular and cellular biology31(14)2984-96(2011 Jul)
Chen CH,Martin VA,Gorenstein NM,Geahlen RL,Post CB

Cloning and functional characterization of chicken stem cell antigen 2.
Developmental and comparative immunology34(3)360-8(2010 Mar)
Mao W,Hunt HD,Cheng HH

Generation of an analog-sensitive Syk tyrosine kinase for the study of signaling dynamics from the B cell antigen receptor.
The Journal of biological chemistry282(46)33760-8(2007 Nov)
Oh H,Ozkirimli E,Shah K,Harrison ML,Geahlen RL

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SYK cDNA ORF clone, Gallus gallus(chicken)

Gene

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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