MYD88 cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	MYD88
Entrez Gene ID	420420
Full Name	myeloid differentiation primary response 88
General protein information	Preferred Names myeloid differentiation primary response 88 Names myeloid differentiation primary response protein MyD88 myeloid differentiation primary response gene (88)
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001030962.3	NP_001026133.2	myeloid differentiation primary response protein MyD88
NM_001030962.4	NP_001026133.2	myeloid differentiation primary response protein MyD88

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	MYD88	XP_534223.2
Rattus norvegicus (Norway rat)	Myd88	NP_937763.1
Mus musculus (house mouse)	Myd88	NP_034981.1
Danio rerio (zebrafish)	myd88	NP_997979.2
Xenopus tropicalis (tropical clawed frog)	myd88	NP_001016837.1
Homo sapiens (human)	MYD88	NP_002459.2
Pan troglodytes (chimpanzee)	MYD88	NP_001123935.1
	MYD88	NP_001124153.1
Bos taurus (cattle)	MYD88	NP_001014404.1
Gallus gallus (chicken)	MYD88	NP_001026133.1
Anopheles gambiae (African malaria mosquito)	MYD	XP_314167.4

Gene Ontology
Bibliography

Related articles in PubMed

Upregulation of chicken TLR4, TLR15 and MyD88 in heterophils and monocyte-derived macrophages stimulated with Eimeria tenella in vitro.
Zhou Z, Wang Z, Cao L, Hu S, Zhang Z, Qin B, Guo Z, Nie K
Experimental parasitology133(4)427-33(2013 Apr)

Up-regulation of the MyD88-dependent pathway of TLR signaling in spleen and caecum of young chickens infected with Salmonella serovar Pullorum.
Li P, Xia P, Wen J, Zheng M, Chen J, Zhao J, Jiang R, Liu R, Zhao G
Veterinary microbiology143(2-4)346-51(2010 Jul)

Expression profiles of genes in Toll-like receptor-mediated signaling of broilers infected with Clostridium perfringens.
Lu Y, Sarson AJ, Gong J, Zhou H, Zhu W, Kang Z, Yu H, Sharif S, Han Y
Clinical and vaccine immunology : CVI16(11)1639-47(2009 Nov)

Molecular cloning and functional characterization of a novel isoform of chicken myeloid differentiation factor 88 (MyD88).
Qiu Y, Shen Y, Li X, Ding C, Ma Z
Developmental and comparative immunology32(12)1522-30(2008)

Molecular cloning and expression analysis of chicken MyD88 and TRIF genes.
Wheaton S, Lambourne MD, Sarson AJ, Brisbin JT, Mayameei A, Sharif S
DNA sequence : the journal of DNA sequencing and mapping18(6)480-6(2007 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The results demonstrated that ChTLR4, ChTLR15 and MyD88 were involved in E. tenella sporozoites recognition and subsequent signal transduction.
Title: Upregulation of chicken TLR4, TLR15 and MyD88 in heterophils and monocyte-derived macrophages stimulated with Eimeria tenella in vitro.

Over-expression of chicken isoform 2 significantly induces activation of NF-kappaB in vitro; chicken MyD88-2 may play an important role in chicken innate immune responses.
Title: Molecular cloning and functional characterization of a novel isoform of chicken myeloid differentiation factor 88 (MyD88).

MyD88 gene expression was detected in each tissue tested except in muscle.
Title: Molecular cloning and expression analysis of chicken MyD88 and TRIF genes.

The following MYD88 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MYD88 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OGa28546	NM_001030962.4 Latest version!	Gallus gallus myeloid differentiation primary response 88 (MYD88), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
View Old Accession Versions >>
OGa28546	NM_001030962.3	Gallus gallus myeloid differentiation primary response 88 (MYD88), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MYD88 ( NM_001030962.3 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_001026133.2 Gallus gallus myeloid differentiation primary response 88 (MYD88), mRNA.

Price & Availability↑

CloneID	OGa28546
Clone ID Related Accession (Same CDS sequence)	NM_001030962.3 , NM_001030962.4
Accession Version	NM_001030962.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 900bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Gallus gallus(chicken)
Product	myeloid differentiation primary response protein MyD88
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AADN04000183.1. On Feb 10, 2016 this sequence version replaced NM_001030962.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AJ851640.1, EF011109.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2201357, SAMEA2201358 [ECO:0000348] ##Evidence-Data-END##

ATGGCTACGG TACCCGTGGG TGCGGGCTCC GCTCCCGGCC CCGAGCCGGC GGATCTGCAC 
TCCGTGCCTA TGGTGGCCCT CAACTACGGC GTGCGGCGCC GCCTCGGCCT TTACCTCAAC 
CCGCGGGCGG CGACCGCCGC CGACTGGACG GCGCTGGCGG AGAAGTTGGG CCACGACTAC 
CTGGAGATCC GGCGGCTGGA GGCGCTGCCC GACCCCACGG CGGCGCTGCT GGAAGAGTGG 
CAGAGCCGCT GTCCCGGCGG AGCCACCGTG GGTCAACTGC TGGAGCTGCT CCGGCAGCTG 
GGCCGCCACG ATGTCCTGCT GGAGCTGGGC GGCAGCGTGG AGGAGGACTG CAAGAAGTAC 
TTACGAAGGA AGCAGCAGGA GGCCGAGCAG CCGCTGCAGG TCCCGGCGGT AGACAGCAGC 
GTGCCAAAGA CTTCAGAGCT GATGGGCATC ACCACGAGGG ATGATCCGTA TGGGCATGGA 
ACAGAGATGT TTGATGCCTT CATCTGCTAC TGTCAGAAAG ACCTTCAGTT TGTCCAGGAG 
ATGATCAGAG AGTTGGAGCA AACGGAGTTC AAACTGAAGC TGTGTGTGTT TGATCGGGAT 
GTCTTGCCAG GAACGTGTGT GTGGTCCATT AGTGGAGAAC TCATAGAAAG AAGGTGTCGG 
AGGATGGTGG TCGTCATTTC AGATGATTAC CTGGAAAGTG ATGAATGTGA TTTTCAGACC 
AAATTTGCTC TTAGTCTTTC CCCAGGGGCT CGTCTCAAGC GGCTGATTCC GGTCAAGTGC 
AAGACCATGA AGAACGAGTT TCCAAGTATC TTGCGGTTCA TTACAATTTG TGATTACACC 
AATCCTTGCA CCAAAAAATG GTTCTGGACA AGACTGGCAA AATCTCTCTT GCTGCCGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001026133.2
CDS	14..913
Translation	MATVPVGAGSAPGPEPADLHSVPMVALNYGVRRRLGLYLNPRAATAADWTALAEKLGHDYLEIRRLEALPDPTAALLEEWQSRCPGGATVGQLLELLRQLGRHDVLLELGGSVEEDCKKYLRRKQQEAEQPLQVPAVDSSVPKTSELMGITTRDDPYGHGTEMFDAFICYCQKDLQFVQEMIRELEQTEFKLKLCVFDRDVLPGTCVWSISGELIERRCRRMVVVISDDYLESDECDFQTKFALSLSPGARLKRLIPVKCKTMKNEFPSILRFITICDYTNPCTKKWFWTRLAKSLLLP

Target ORF information:

RefSeq Version	NM_001030962.3
Organism	Gallus gallus(chicken)
Definition	Gallus gallus myeloid differentiation primary response 88 (MYD88), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001030962.3

ORF Insert Sequence:

ATGGCTACGG TACCCGTGGG TGCGGGCTCC GCTCCCGGCC CCGAGCCGGC GGATCTGCAC 
TCCGTGCCTA TGGTGGCCCT CAACTACGGC GTGCGGCGCC GCCTCGGCCT TTACCTCAAC 
CCGCGGGCGG CGACCGCCGC CGACTGGACG GCGCTGGCGG AGAAGTTGGG CCACGACTAC 
CTGGAGATCC GGCGGCTGGA GGCGCTGCCC GACCCCACGG CGGCGCTGCT GGAAGAGTGG 
CAGAGCCGCT GTCCCGGCGG AGCCACCGTG GGTCAACTGC TGGAGCTGCT CCGGCAGCTG 
GGCCGCCACG ATGTCCTGCT GGAGCTGGGC GGCAGCGTGG AGGAGGACTG CAAGAAGTAC 
TTACGAAGGA AGCAGCAGGA GGCCGAGCAG CCGCTGCAGG TCCCGGCGGT AGACAGCAGC 
GTGCCAAAGA CTTCAGAGCT GATGGGCATC ACCACGAGGG ATGATCCGTA TGGGCATGGA 
ACAGAGATGT TTGATGCCTT CATCTGCTAC TGTCAGAAAG ACCTTCAGTT TGTCCAGGAG 
ATGATCAGAG AGTTGGAGCA AACGGAGTTC AAACTGAAGC TGTGTGTGTT TGATCGGGAT 
GTCTTGCCAG GAACGTGTGT GTGGTCCATT AGTGGAGAAC TCATAGAAAG AAGGTGTCGG 
AGGATGGTGG TCGTCATTTC AGATGATTAC CTGGAAAGTG ATGAATGTGA TTTTCAGACC 
AAATTTGCTC TTAGTCTTTC CCCAGGGGCT CGTCTCAAGC GGCTGATTCC GGTCAAGTGC 
AAGACCATGA AGAACGAGTT TCCAAGTATC TTGCGGTTCA TTACAATTTG TGATTACACC 
AATCCTTGCA CCAAAAAATG GTTCTGGACA AGACTGGCAA AATCTCTCTT GCTGCCGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MYD88 ( NM_001030962.4 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_001026133.2 Gallus gallus myeloid differentiation primary response 88 (MYD88), mRNA.

Price & Availability↑

CloneID	OGa28546
Clone ID Related Accession (Same CDS sequence)	NM_001030962.3 , NM_001030962.4
Accession Version	NM_001030962.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 900bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Gallus gallus(chicken)
Product	myeloid differentiation primary response protein MyD88
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AADN05000033.1. On Jun 26, 2018 this sequence version replaced NM_001030962.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AJ851640.1, HAEK01016323.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2201357, SAMEA2201358 [ECO:0000348] ##Evidence-Data-END##

ATGGCTACGG TACCCGTGGG TGCGGGCTCC GCTCCCGGCC CCGAGCCGGC GGATCTGCAC 
TCCGTGCCTA TGGTGGCCCT CAACTACGGC GTGCGGCGCC GCCTCGGCCT TTACCTCAAC 
CCGCGGGCGG CGACCGCCGC CGACTGGACG GCGCTGGCGG AGAAGTTGGG CCACGACTAC 
CTGGAGATCC GGCGGCTGGA GGCGCTGCCC GACCCCACGG CGGCGCTGCT GGAAGAGTGG 
CAGAGCCGCT GTCCCGGCGG AGCCACCGTG GGTCAACTGC TGGAGCTGCT CCGGCAGCTG 
GGCCGCCACG ATGTCCTGCT GGAGCTGGGC GGCAGCGTGG AGGAGGACTG CAAGAAGTAC 
TTACGAAGGA AGCAGCAGGA GGCCGAGCAG CCGCTGCAGG TCCCGGCGGT AGACAGCAGC 
GTGCCAAAGA CTTCAGAGCT GATGGGCATC ACCACGAGGG ATGATCCGTA TGGGCATGGA 
ACAGAGATGT TTGATGCCTT CATCTGCTAC TGTCAGAAAG ACCTTCAGTT TGTCCAGGAG 
ATGATCAGAG AGTTGGAGCA AACGGAGTTC AAACTGAAGC TGTGTGTGTT TGATCGGGAT 
GTCTTGCCAG GAACGTGTGT GTGGTCCATT AGTGGAGAAC TCATAGAAAG AAGGTGTCGG 
AGGATGGTGG TCGTCATTTC AGATGATTAC CTGGAAAGTG ATGAATGTGA TTTTCAGACC 
AAATTTGCTC TTAGTCTTTC CCCAGGGGCT CGTCTCAAGC GGCTGATTCC GGTCAAGTGC 
AAGACCATGA AGAACGAGTT TCCAAGTATC TTGCGGTTCA TTACAATTTG TGATTACACC 
AATCCTTGCA CCAAAAAATG GTTCTGGACA AGACTGGCAA AATCTCTCTT GCTGCCGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001026133.2
CDS	14..913
Translation	MATVPVGAGSAPGPEPADLHSVPMVALNYGVRRRLGLYLNPRAATAADWTALAEKLGHDYLEIRRLEALPDPTAALLEEWQSRCPGGATVGQLLELLRQLGRHDVLLELGGSVEEDCKKYLRRKQQEAEQPLQVPAVDSSVPKTSELMGITTRDDPYGHGTEMFDAFICYCQKDLQFVQEMIRELEQTEFKLKLCVFDRDVLPGTCVWSISGELIERRCRRMVVVISDDYLESDECDFQTKFALSLSPGARLKRLIPVKCKTMKNEFPSILRFITICDYTNPCTKKWFWTRLAKSLLLP

Target ORF information:

RefSeq Version	NM_001030962.4
Organism	Gallus gallus(chicken)
Definition	Gallus gallus myeloid differentiation primary response 88 (MYD88), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001030962.4

ORF Insert Sequence:

ATGGCTACGG TACCCGTGGG TGCGGGCTCC GCTCCCGGCC CCGAGCCGGC GGATCTGCAC 
TCCGTGCCTA TGGTGGCCCT CAACTACGGC GTGCGGCGCC GCCTCGGCCT TTACCTCAAC 
CCGCGGGCGG CGACCGCCGC CGACTGGACG GCGCTGGCGG AGAAGTTGGG CCACGACTAC 
CTGGAGATCC GGCGGCTGGA GGCGCTGCCC GACCCCACGG CGGCGCTGCT GGAAGAGTGG 
CAGAGCCGCT GTCCCGGCGG AGCCACCGTG GGTCAACTGC TGGAGCTGCT CCGGCAGCTG 
GGCCGCCACG ATGTCCTGCT GGAGCTGGGC GGCAGCGTGG AGGAGGACTG CAAGAAGTAC 
TTACGAAGGA AGCAGCAGGA GGCCGAGCAG CCGCTGCAGG TCCCGGCGGT AGACAGCAGC 
GTGCCAAAGA CTTCAGAGCT GATGGGCATC ACCACGAGGG ATGATCCGTA TGGGCATGGA 
ACAGAGATGT TTGATGCCTT CATCTGCTAC TGTCAGAAAG ACCTTCAGTT TGTCCAGGAG 
ATGATCAGAG AGTTGGAGCA AACGGAGTTC AAACTGAAGC TGTGTGTGTT TGATCGGGAT 
GTCTTGCCAG GAACGTGTGT GTGGTCCATT AGTGGAGAAC TCATAGAAAG AAGGTGTCGG 
AGGATGGTGG TCGTCATTTC AGATGATTAC CTGGAAAGTG ATGAATGTGA TTTTCAGACC 
AAATTTGCTC TTAGTCTTTC CCCAGGGGCT CGTCTCAAGC GGCTGATTCC GGTCAAGTGC 
AAGACCATGA AGAACGAGTT TCCAAGTATC TTGCGGTTCA TTACAATTTG TGATTACACC 
AATCCTTGCA CCAAAAAATG GTTCTGGACA AGACTGGCAA AATCTCTCTT GCTGCCGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Upregulation of chicken TLR4, TLR15 and MyD88 in heterophils and monocyte-derived macrophages stimulated with Eimeria tenella in vitro.
Experimental parasitology133(4)427-33(2013 Apr)
Zhou Z,Wang Z,Cao L,Hu S,Zhang Z,Qin B,Guo Z,Nie K

Up-regulation of the MyD88-dependent pathway of TLR signaling in spleen and caecum of young chickens infected with Salmonella serovar Pullorum.
Veterinary microbiology143(2-4)346-51(2010 Jul)
Li P,Xia P,Wen J,Zheng M,Chen J,Zhao J,Jiang R,Liu R,Zhao G

Expression profiles of genes in Toll-like receptor-mediated signaling of broilers infected with Clostridium perfringens.
Clinical and vaccine immunology : CVI16(11)1639-47(2009 Nov)
Lu Y,Sarson AJ,Gong J,Zhou H,Zhu W,Kang Z,Yu H,Sharif S,Han Y

Molecular cloning and functional characterization of a novel isoform of chicken myeloid differentiation factor 88 (MyD88).
Developmental and comparative immunology32(12)1522-30(2008)
Qiu Y,Shen Y,Li X,Ding C,Ma Z

Molecular cloning and expression analysis of chicken MyD88 and TRIF genes.
DNA sequence : the journal of DNA sequencing and mapping18(6)480-6(2007 Dec)
Wheaton S,Lambourne MD,Sarson AJ,Brisbin JT,Mayameei A,Sharif S

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MYD88 cDNA ORF clone, Gallus gallus(chicken)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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