AvBD12 cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	AvBD12
Entrez Gene ID	414339
Full Name	avian beta-defensin 12
Synonyms	GAL12,Gal-10,Gal10,gal-12
General protein information	Preferred Names avian beta-defensin 12 Names gallinacin-12 beta-defensin 12 gallinacin-10
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001001607.2	NP_001001607.2	gallinacin-12 prepropeptide precursor

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Avian host defense peptides.
Cuperus T, Coorens M, van Dijk A, Haagsman HP
Developmental and comparative immunology41(3)352-69(2013 Nov)

Primary structure and antibacterial activity of chicken bone marrow-derived beta-defensins.
Derache C, Labas V, Aucagne V, Meudal H, Landon C, Delmas AF, Magallon T, Lalmanach AC
Antimicrobial agents and chemotherapy53(11)4647-55(2009 Nov)

Avian beta-defensin nomenclature: a community proposed update.
Lynn DJ, Higgs R, Lloyd AT, O'Farrelly C, Herv?-Gr?pinet V, Nys Y, Brinkman FS, Yu PL, Soulier A, Kaiser P, Zhang G, Lehrer RI
Immunology letters110(1)86-9(2007 May)

A genome-wide screen identifies a single beta-defensin gene cluster in the chicken: implications for the origin and evolution of mammalian defensins.
Xiao Y, Hughes AL, Ando J, Matsuda Y, Cheng JF, Skinner-Noble D, Zhang G
BMC genomics5(1)56(2004 Aug)

Bioinformatic discovery and initial characterisation of nine novel antimicrobial peptide genes in the chicken.
Lynn DJ, Higgs R, Gaines S, Tierney J, James T, Lloyd AT, Fares MA, Mulcahy G, O'Farrelly C
Immunogenetics56(3)170-7(2004 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The chicken genome encodes only beta-defensins. The 13 chicken beta-defensin genes are clustered densely within a 86-Kb distance on the chromosome 3q3.5-q3.7. The deduced peptides share the characteristic defensin motif.
Title: A genome-wide screen identifies a single beta-defensin gene cluster in the chicken: implications for the origin and evolution of mammalian defensins.

The following AvBD12 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the AvBD12 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa26965	NM_001001607.2 Latest version!	Gallus gallus avian beta-defensin 12 (AvBD12), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

AvBD12 ( NM_001001607.2 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_001001607.2 Gallus gallus avian beta-defensin 12 (AvBD12), mRNA.

Price & Availability↑

CloneID	OGa26965
Clone ID Related Accession (Same CDS sequence)	NM_001001607.2
Accession Version	NM_001001607.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 198bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Gallus gallus(chicken)
Product	gallinacin-12 prepropeptide precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY621314.1. On Jun 20, 2004 this sequence version replaced NM_001001607.1. ##Evidence-Data-START## Transcript exon combination :: AY621314.1, BX257297.4 [ECO:0000332] ##Evidence-Data-END##

ATGAGGAACC TTTGTTTCGT GTTCATCTTC ATCTCCCTGC TCGCTCACGG AAGCACTCAC 
GGCCCAGACA GCTGTAACCA CGACAGGGGA TTGTCCCGAG TGGGGAACTG CAACCCTGGG 
GAATACCTGG CTAAGTACTG CTTTGAACCC GTCATTCTCT GCTGTAAACC TCTGTCACCA 
ACTCCCACCA AGACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001001607.2
CDS	36..233
Translation	MRNLCFVFIFISLLAHGSTHGPDSCNHDRGLSRVGNCNPGEYLAKYCFEPVILCCKPLSPTPTKT

Target ORF information:

RefSeq Version	NM_001001607.2
Organism	Gallus gallus(chicken)
Definition	Gallus gallus avian beta-defensin 12 (AvBD12), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001001607.2

ORF Insert Sequence:

ATGAGGAACC TTTGTTTCGT GTTCATCTTC ATCTCCCTGC TCGCTCACGG AAGCACTCAC 
GGCCCAGACA GCTGTAACCA CGACAGGGGA TTGTCCCGAG TGGGGAACTG CAACCCTGGG 
GAATACCTGG CTAAGTACTG CTTTGAACCC GTCATTCTCT GCTGTAAACC TCTGTCACCA 
ACTCCCACCA AGACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Avian host defense peptides.
Developmental and comparative immunology41(3)352-69(2013 Nov)
Cuperus T,Coorens M,van Dijk A,Haagsman HP

Primary structure and antibacterial activity of chicken bone marrow-derived beta-defensins.
Antimicrobial agents and chemotherapy53(11)4647-55(2009 Nov)
Derache C,Labas V,Aucagne V,Meudal H,Landon C,Delmas AF,Magallon T,Lalmanach AC

Avian beta-defensin nomenclature: a community proposed update.
Immunology letters110(1)86-9(2007 May)
Lynn DJ,Higgs R,Lloyd AT,O'Farrelly C,Herv?-Gr?pinet V,Nys Y,Brinkman FS,Yu PL,Soulier A,Kaiser P,Zhang G,Lehrer RI

A genome-wide screen identifies a single beta-defensin gene cluster in the chicken: implications for the origin and evolution of mammalian defensins.
BMC genomics5(1)56(2004 Aug)
Xiao Y,Hughes AL,Ando J,Matsuda Y,Cheng JF,Skinner-Noble D,Zhang G

Bioinformatic discovery and initial characterisation of nine novel antimicrobial peptide genes in the chicken.
Immunogenetics56(3)170-7(2004 Jun)
Lynn DJ,Higgs R,Gaines S,Tierney J,James T,Lloyd AT,Fares MA,Mulcahy G,O'Farrelly C