SKIL cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	SKIL
Entrez Gene ID	396087
Full Name	SKI like proto-oncogene
Synonyms	SNO,c-sno
General protein information	Preferred Names SKI like proto-oncogene Names ski-like protein SKI-like oncogene ski-related snoN
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_205174.2	NP_990505.1	ski-like protein

Pathways from BioSystems

Homologies

Bos taurus (cattle)	SKIL	NP_001192876.1
Rattus norvegicus (Norway rat)	Skil	XP_006232299.1
Gallus gallus (chicken)	SKIL	NP_990505.1
Pan troglodytes (chimpanzee)	SKIL	XP_001163447.1
Canis lupus familiaris (dog)	SKIL	XP_545283.2
Mus musculus (house mouse)	Skil	NP_035516.2
Danio rerio (zebrafish)	LOC100007653	XP_005171386.1
	SKIL	XP_001085298.2
Homo sapiens (human)	SKIL	NP_001234937.1
Xenopus tropicalis (tropical clawed frog)	skil	XP_002931592.1

Gene Ontology
Bibliography

Related articles in PubMed

Transforming growth factors beta coordinate cartilage and tendon differentiation in the developing limb mesenchyme.
Lorda-Diez CI, Montero JA, Martinez-Cue C, Garcia-Porrero JA, Hurle JM
The Journal of biological chemistry284(43)29988-96(2009 Oct)

Sumoylated SnoN represses transcription in a promoter-specific manner.
Hsu YH, Sarker KP, Pot I, Chan A, Netherton SJ, Bonni S
The Journal of biological chemistry281(44)33008-18(2006 Nov)

Isolation and characterization of the chicken c-sno gene.
Givol I, Boyer PL, Hughes SH
Gene156(2)271-6(1995 Apr)

Sequence and biological activity of chicken snoN cDNA clones.
Boyer PL, Colmenares C, Stavnezer E, Hughes SH
Oncogene8(2)457-66(1993 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

SnoN (SKIL) is expressed in the tip of the growing digit cartilage primordia, and in the developing joints. The addition of TGF beta in micromass cultures is quickly followed by an intense up-regulation of this TGF beta-signaling repressor.
Title: Transforming growth factors beta coordinate cartilage and tendon differentiation in the developing limb mesenchyme.

SnoN is directly regulated by sumoylation leading to the enhancement of the ability of SnoN to repress transcription in a promoter-specific manner
Title: Sumoylated SnoN represses transcription in a promoter-specific manner.

The following SKIL gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SKIL cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa25936	NM_205174.2 Latest version!	Gallus gallus SKI like proto-oncogene (SKIL), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$426.30 $609.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SKIL ( NM_205174.2 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_990505.1 Gallus gallus SKI like proto-oncogene (SKIL), mRNA.

Price & Availability↑

CloneID	OGa25936
Clone ID Related Accession (Same CDS sequence)	NM_205174.2
Accession Version	NM_205174.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2073bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-20
Organism	Gallus gallus(chicken)
Product	ski-like protein
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from S53899.1. On Jun 3, 2007 this sequence version replaced NM_205174.1. ##Evidence-Data-START## Transcript exon combination :: S53899.1 [ECO:0000332] ##Evidence-Data-END##

ATGGAAAGCC CACAAGCAAA TTTCCCTCTA GGGCTCGTTT CAGAGCAAAA GAGGAGTGGG 
ATGCAGGAGG ATGGGAGCCC CCCACTGAAA AAGCTGATGA CAGAAATGCA CGTAAATAGC 
CCGGTACAGG TTGTAATAAA TAAACTGCCA ACAATAAAGA AGGAAAACTT GGACGAATAT 
GACGAAACTT CTGTGGAGGC TGACGGGGAG AGTGCCAAGC CAAACAGTTC TTCAGTCTCT 
GAGCCTTTGA ATTTAAATCC AGGTCTGAAA CACACGTTGG CACAATTCCA CTTGAGCAGC 
CAGAGCTCGC TGGGTGGACC AGCAGCTTTC TCAGCTCGCT ATTCCCAGGA AAGCATGTCA 
CCCACTGTCT TCTTGCCTCT TCCATCACCA CAAATCCTGT CTCTGCCGCT GCTCATTCCT 
CCCGACAGCT CCACAGAGCT CACTCAGACT GTACTGGAGG GGGAATCCAT CTCTTGCTTT 
AAAGTTGGAG GAGAAAAAAG ACTCTGCCTG CCTCAGGTGT TGAATTCAGT TCTTCGAGAC 
TTTTCTTTGC AACAGATTAA TACAGTGTGT GACGAACTGT ACATATACTG CTCCAGGTGC 
ACTTCCGACC AGCTTCATAT TCTGAAGGTT TTGGGAATTC TTCCATTTAA TGCTCCGTCC 
TGCGGGCTAA TTACACTGAC TGATGCTCAG AGACTATGCA ATGCTTTACT ACGTCCTCGC 
ACTTTTCCTC AAAATGGTGG CTTTCTGCCT GGTAAGAACA CGTTGGCCCA ACTGAAGGAG 
ACTGGCAGTG CCTTTGAAGT AGAGCACGAA TGCCTGGGCA AGTGCCAGGG TTTGTTTGCA 
CCTCAGTTCT ACCTTGCGCC GGACGACCCC TGTATACAGT GTCTGGAGTG CTACGGGATG 
TTCTCACCCC AGACCTTCGT GATGCATTCA CATCGATCCC CCGACAAGAG GACCTGCCAC 
TGGGGGTTTG AGTCAGCCAA GTGGCACTGC TACCTTCATA TTAACCAAAA ATACCTGGGA 
ACGTCGGAGG AGCGGGAACT GAAGCATCTC TTGGAGGAAA TGAAGGAGAA ATTTAGTGAG 
AAAAATCAGA AAAGAACTCG ATCAAAAGTG GATTCCCAGC AGAGCCTAGA ATTATCACAG 
TGGTATCCTG TTATAAAGCA GGAAGCAGAA GCTGATCCTC AGCCACCCTC CTTCTTCCAT 
CCCAGTTACT ACCTTTATAT GTGTGATAAA GTGGTTGCCC CAAATGTATC TCTTGCATCA 
CAATACAAGG ATGTTACAAA AACAACAGGC AAAGCTTCTG AAGTAATTAA GTCTTCATCT 
GGAACGTCAG AGAAGAAGCT CAGTAGTGGA AAGCACAAAA AACCTGCCTC CTATCCAGAG 
CTTTCTCTTG AGGAACAGGA GAAAATTGAC TTGAAAACTG GTCTGGAGCA GCATAAGCGT 
TTAGACCCCC TTGTATCAGC TCATTCTGCA AGAGGTGGAA GATCCGAACG TATTTCTTCC 
AAAAGCATTA GAGGCTCCAG ATGTGTTGAA GTAGGTAATG ATGGGAGAAC GTTGTCCCCC 
ACTCTCATGA AAGACATCAG TTGTGAAGAC GACAAGGGAA GGATCATGGA AGAAGTAATG 
AAAACCTACA TCAAACAGCA AGAAAAACTA AATACTATTT TGCGGAGGAA GCAGCAGCTT 
CAAATGGAAG TGGAAATGTT AAACAACTCT AAAGCTATGA AGGAACTAAG TGAAGAGCAG 
CAGAATTTGC AAAAAGAACT TGAATCTTTG CAAACTGAGC ACGCTCAAAG AATGGAAGAG 
TTTTATTTTG AGCAGAGAGA CTTGGAGAAG AAATTGGACC AAATGATGAA GCAGAAGTGT 
ACCTGTGACT CCAGTTCAGA GAAGGACAAG GAAGCAGAAT ATGCAGCACA GCTAGCAGAA 
CTGAGACAGA GACTGGACCA CGCAGAGGCA GATAGGCAGG AGCTTCAAGA TGAACTGAGA 
CAAGAACGAG AGGCAAGGGA AAAGTTAGAG ATGATGATAA AAGAATTGAA GCTACAGATC 
TTGAAATCTT CAAAAAATGG AAATGGAAAA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_990505.1
CDS	243..2315
Translation	MESPQANFPLGLVSEQKRSGMQEDGSPPLKKLMTEMHVNSPVQVVINKLPTIKKENLDEYDETSVEADGESAKPNSSSVSEPLNLNPGLKHTLAQFHLSSQSSLGGPAAFSARYSQESMSPTVFLPLPSPQILSLPLLIPPDSSTELTQTVLEGESISCFKVGGEKRLCLPQVLNSVLRDFSLQQINTVCDELYIYCSRCTSDQLHILKVLGILPFNAPSCGLITLTDAQRLCNALLRPRTFPQNGGFLPGKNTLAQLKETGSAFEVEHECLGKCQGLFAPQFYLAPDDPCIQCLECYGMFSPQTFVMHSHRSPDKRTCHWGFESAKWHCYLHINQKYLGTSEERELKHLLEEMKEKFSEKNQKRTRSKVDSQQSLELSQWYPVIKQEAEADPQPPSFFHPSYYLYMCDKVVAPNVSLASQYKDVTKTTGKASEVIKSSSGTSEKKLSSGKHKKPASYPELSLEEQEKIDLKTGLEQHKRLDPLVSAHSARGGRSERISSKSIRGSRCVEVGNDGRTLSPTLMKDISCEDDKGRIMEEVMKTYIKQQEKLNTILRRKQQLQMEVEMLNNSKAMKELSEEQQNLQKELESLQTEHAQRMEEFYFEQRDLEKKLDQMMKQKCTCDSSSEKDKEAEYAAQLAELRQRLDHAEADRQELQDELRQEREAREKLEMMIKELKLQILKSSKNGNGK

Target ORF information:

RefSeq Version	NM_205174.2
Organism	Gallus gallus(chicken)
Definition	Gallus gallus SKI like proto-oncogene (SKIL), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_205174.2

ORF Insert Sequence:

ATGGAAAGCC CACAAGCAAA TTTCCCTCTA GGGCTCGTTT CAGAGCAAAA GAGGAGTGGG 
ATGCAGGAGG ATGGGAGCCC CCCACTGAAA AAGCTGATGA CAGAAATGCA CGTAAATAGC 
CCGGTACAGG TTGTAATAAA TAAACTGCCA ACAATAAAGA AGGAAAACTT GGACGAATAT 
GACGAAACTT CTGTGGAGGC TGACGGGGAG AGTGCCAAGC CAAACAGTTC TTCAGTCTCT 
GAGCCTTTGA ATTTAAATCC AGGTCTGAAA CACACGTTGG CACAATTCCA CTTGAGCAGC 
CAGAGCTCGC TGGGTGGACC AGCAGCTTTC TCAGCTCGCT ATTCCCAGGA AAGCATGTCA 
CCCACTGTCT TCTTGCCTCT TCCATCACCA CAAATCCTGT CTCTGCCGCT GCTCATTCCT 
CCCGACAGCT CCACAGAGCT CACTCAGACT GTACTGGAGG GGGAATCCAT CTCTTGCTTT 
AAAGTTGGAG GAGAAAAAAG ACTCTGCCTG CCTCAGGTGT TGAATTCAGT TCTTCGAGAC 
TTTTCTTTGC AACAGATTAA TACAGTGTGT GACGAACTGT ACATATACTG CTCCAGGTGC 
ACTTCCGACC AGCTTCATAT TCTGAAGGTT TTGGGAATTC TTCCATTTAA TGCTCCGTCC 
TGCGGGCTAA TTACACTGAC TGATGCTCAG AGACTATGCA ATGCTTTACT ACGTCCTCGC 
ACTTTTCCTC AAAATGGTGG CTTTCTGCCT GGTAAGAACA CGTTGGCCCA ACTGAAGGAG 
ACTGGCAGTG CCTTTGAAGT AGAGCACGAA TGCCTGGGCA AGTGCCAGGG TTTGTTTGCA 
CCTCAGTTCT ACCTTGCGCC GGACGACCCC TGTATACAGT GTCTGGAGTG CTACGGGATG 
TTCTCACCCC AGACCTTCGT GATGCATTCA CATCGATCCC CCGACAAGAG GACCTGCCAC 
TGGGGGTTTG AGTCAGCCAA GTGGCACTGC TACCTTCATA TTAACCAAAA ATACCTGGGA 
ACGTCGGAGG AGCGGGAACT GAAGCATCTC TTGGAGGAAA TGAAGGAGAA ATTTAGTGAG 
AAAAATCAGA AAAGAACTCG ATCAAAAGTG GATTCCCAGC AGAGCCTAGA ATTATCACAG 
TGGTATCCTG TTATAAAGCA GGAAGCAGAA GCTGATCCTC AGCCACCCTC CTTCTTCCAT 
CCCAGTTACT ACCTTTATAT GTGTGATAAA GTGGTTGCCC CAAATGTATC TCTTGCATCA 
CAATACAAGG ATGTTACAAA AACAACAGGC AAAGCTTCTG AAGTAATTAA GTCTTCATCT 
GGAACGTCAG AGAAGAAGCT CAGTAGTGGA AAGCACAAAA AACCTGCCTC CTATCCAGAG 
CTTTCTCTTG AGGAACAGGA GAAAATTGAC TTGAAAACTG GTCTGGAGCA GCATAAGCGT 
TTAGACCCCC TTGTATCAGC TCATTCTGCA AGAGGTGGAA GATCCGAACG TATTTCTTCC 
AAAAGCATTA GAGGCTCCAG ATGTGTTGAA GTAGGTAATG ATGGGAGAAC GTTGTCCCCC 
ACTCTCATGA AAGACATCAG TTGTGAAGAC GACAAGGGAA GGATCATGGA AGAAGTAATG 
AAAACCTACA TCAAACAGCA AGAAAAACTA AATACTATTT TGCGGAGGAA GCAGCAGCTT 
CAAATGGAAG TGGAAATGTT AAACAACTCT AAAGCTATGA AGGAACTAAG TGAAGAGCAG 
CAGAATTTGC AAAAAGAACT TGAATCTTTG CAAACTGAGC ACGCTCAAAG AATGGAAGAG 
TTTTATTTTG AGCAGAGAGA CTTGGAGAAG AAATTGGACC AAATGATGAA GCAGAAGTGT 
ACCTGTGACT CCAGTTCAGA GAAGGACAAG GAAGCAGAAT ATGCAGCACA GCTAGCAGAA 
CTGAGACAGA GACTGGACCA CGCAGAGGCA GATAGGCAGG AGCTTCAAGA TGAACTGAGA 
CAAGAACGAG AGGCAAGGGA AAAGTTAGAG ATGATGATAA AAGAATTGAA GCTACAGATC 
TTGAAATCTT CAAAAAATGG AAATGGAAAA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Transforming growth factors beta coordinate cartilage and tendon differentiation in the developing limb mesenchyme.
The Journal of biological chemistry284(43)29988-96(2009 Oct)
Lorda-Diez CI,Montero JA,Martinez-Cue C,Garcia-Porrero JA,Hurle JM

Sumoylated SnoN represses transcription in a promoter-specific manner.
The Journal of biological chemistry281(44)33008-18(2006 Nov)
Hsu YH,Sarker KP,Pot I,Chan A,Netherton SJ,Bonni S

Isolation and characterization of the chicken c-sno gene.
Gene156(2)271-6(1995 Apr)
Givol I,Boyer PL,Hughes SH

Sequence and biological activity of chicken snoN cDNA clones.
Oncogene8(2)457-66(1993 Feb)
Boyer PL,Colmenares C,Stavnezer E,Hughes SH

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SKIL cDNA ORF clone, Gallus gallus(chicken)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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