AKT1 cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	AKT1
Entrez Gene ID	395928
Full Name	AKT serine/threonine kinase 1
General protein information	Preferred Names AKT serine/threonine kinase 1 Names RAC-alpha serine/threonine-protein kinase serine/threonine protein kinase v-akt murine thymoma viral oncogene homolog 1
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_205055.1	NP_990386.1	RAC-alpha serine/threonine-protein kinase

Pathways from BioSystems

Homologies

Bos taurus (cattle)	AKT1	NP_776411.1
Caenorhabditis elegans (roundworm)	akt-2	NP_510357.3
Homo sapiens (human)	AKT1	NP_001014431.1
Canis lupus familiaris (dog)	AKT1	XP_548000.3
Mus musculus (house mouse)	Akt1	NP_033782.1
Gallus gallus (chicken)	AKT1	NP_990386.1
Pan troglodytes (chimpanzee)	AKT1	XP_001143158.2
	AKT1	XP_001085265.2
Rattus norvegicus (Norway rat)	Akt1	NP_150233.1
Danio rerio (zebrafish)	LOC100331515	XP_003200336.2
Caenorhabditis elegans (roundworm)	akt-1	NP_001023646.1
Xenopus tropicalis (tropical clawed frog)	akt1	XP_004917249.1

Gene Ontology
Bibliography

Related articles in PubMed

Transient activation of the PI3K/Akt pathway promotes Newcastle disease virus replication and enhances anti-apoptotic signaling responses.
Kang Y, Yuan R, Zhao X, Xiang B, Gao S, Gao P, Dai X, Feng M, Li Y, Xie P, Li Y, Gao X, Ren T
Oncotarget8(14)23551-23563(2017 Apr)

Gene expression pattern of glucose transporters in the skeletal muscles of newly hatched chicks.
Shimamoto S, Ijiri D, Kawaguchi M, Nakashima K, Ohtsuka A
Bioscience, biotechnology, and biochemistry80(7)1382-5(2016 Jul)

AKT signaling mediates IGF-I survival actions on otic neural progenitors.
Aburto MR, Magari?os M, Leon Y, Varela-Nieto I, Sanchez-Calderon H
PloS one7(1)e30790(2012)

The PI3K/Akt pathway is involved in early infection of some exogenous avian leukosis viruses.
Feng SZ, Cao WS, Liao M
The Journal of general virology92(Pt 7)1688-97(2011 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data suggest that by suppressing premature apoptosis upon Newcastle disease virus (NDV) infection, the PI3K/Akt pathway enhances the anti-apoptotic response.
Title: Transient activation of the PI3K/Akt pathway promotes Newcastle disease virus replication and enhances anti-apoptotic signaling responses.

Phosphorylated AKT level was high in the skeletal muscles, suggesting a relationship between AKT and GLUT1 expression.
Title: Gene expression pattern of glucose transporters in the skeletal muscles of newly hatched chicks.

Proliferative otic neuroblasts are dependent on the activation of the PI3K-AKT pathway by IGF-I for survival during the otic neuronal progenitor phase of early inner ear development.
Title: AKT signaling mediates IGF-I survival actions on otic neural progenitors.

The PI3K/Akt pathway is involved in early infection avian leukosis viruses.
Title: The PI3K/Akt pathway is involved in early infection of some exogenous avian leukosis viruses.

These findings suggest that integrity of the actin cytoskeleton is a crucial requirement for PI3K/Akt and p38 MAPK in chondrocyte redifferentiation.
Title: Integrity of the cortical actin ring is required for activation of the PI3K/Akt and p38 MAPK signaling pathways in redifferentiation of chondrocytes on chitosan.

The following AKT1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the AKT1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa25926	NM_205055.1 Latest version!	Gallus gallus AKT serine/threonine kinase 1 (AKT1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

AKT1 ( NM_205055.1 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_990386.1 Gallus gallus AKT serine/threonine kinase 1 (AKT1), mRNA.

Price & Availability↑

CloneID	OGa25926
Clone ID Related Accession (Same CDS sequence)	NM_205055.1
Accession Version	NM_205055.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1443bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-20
Organism	Gallus gallus(chicken)
Product	RAC-alpha serine/threonine-protein kinase
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF039943.1. ##Evidence-Data-START## Transcript exon combination :: AF039943.1 [ECO:0000332] ##Evidence-Data-END##

ATGAATGAAG TAGCGATAGT GAAGGAAGGA TGGCTCCACA AACGAGGAGA ATATATCAAA 
ACATGGAGGC CACGGTATTT TCTTTTAAAG AATGATGGCA CATTCATTGG CTACAAGGAA 
CGACCGCAAG ACGTTGACCA ACGAGAATCA CCTTTAAATA ACTTCTCAGT AGCTCAGTGC 
CAGCTGATGA AGACAGAACG ACCTAAACCA AACACATTTA TCATTAGATG CCTCCAGTGG 
ACCACAGTAA TTGAAAGAAC ATTTCATGTG GAGACTCCAG AGGAGCGGGA AGAATGGACA 
AAAGCTATCC AAACTGTTGC AGACAGCCTC AAGAAACAGG AGGAAGAGAT GATGGATTTT 
AGATCTGGTT CTCCTAGTGA TAATTCAGGT GCTGAAGAAA TGGAAGTTTC TATGACAAAG 
CCAAAACACA AAGTGACCAT GAATGAATTT GAATACCTTA AGCTACTGGG AAAAGGCACT 
TTTGGAAAGG TCATTTTAGT TAAAGAAAAA GCAACCGGAC GGTATTATGC TATGAAAATT 
CTGAAGAAGG AAGTTATTGT AGCAAAGGAT GAAGTAGCAC ACACGCTGAC AGAAAACCGT 
GTTTTACAGA ACTCACGGCA TCCATTCTTA ACAGCTTTAA AGTATTCCTT TCAGACACAC 
GATCGCTTGT GTTTTGTTAT GGAGTATGCT AACGGAGGGG AGTTGTTTTT CCATCTGTCG 
AGAGAGCGTG TATTTTCTGA AGACCGGGCG CGTTTTTATG GGGCTGAGAT TGTTTCAGCG 
CTGGATTACC TGCATTCAGA GAAGAATGTG GTGTACAGAG ATTTGAAGCT GGAAAATCTT 
ATGCTGGATA AAGACGGGCA CATAAAAATT ACAGACTTTG GACTATGTAA AGAAGGCATA 
AAAGATGGAG CAACAATGAA GACTTTCTGT GGCACTCCAG AGTATCTTGC ACCAGAGGTG 
CTGGAGGATA ATGACTATGG TCGTGCAGTG GACTGGTGGG GATTAGGAGT TGTGATGTAT 
GAAATGATGT GTGGCCGGCT CCCTTTCTAC AATCAGGACC ATGAAAAGCT CTTTGAACTC 
ATCCTTATGG AAGAGATTAG ATTTCCACGC ACTTTGTCAC CTGAAGCAAA ATCTCTCTTG 
TCAGGTTTGC TGAAGAAAGA TCCTAAGCAA AGGTTAGGAG GCGGTCCTGA TGATGCCAAG 
GAGATTATGC AGCACAAATT CTTTGCTGGC ATTGTTTGGC AAGATGTATA CGGGAAGAAG 
CTTGTACCTC CATTTAAGCC ACAAGTTACA TCTGAAACAG ATACAAGATA CTTTGATGAA 
GAATTTACAG CACAGATGAT TACAATCACT CCTCCTGACC AAGATGACAG CATGGATTGT 
GTAGACAATG AGAGAAGACC TCATTTTCCT CAGTTCTCCT ATTCAGCCAG TGGAACCGCT 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_990386.1
CDS	466..1908
Translation	MNEVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQRESPLNNFSVAQCQLMKTERPKPNTFIIRCLQWTTVIERTFHVETPEEREEWTKAIQTVADSLKKQEEEMMDFRSGSPSDNSGAEEMEVSMTKPKHKVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLSPEAKSLLSGLLKKDPKQRLGGGPDDAKEIMQHKFFAGIVWQDVYGKKLVPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMDCVDNERRPHFPQFSYSASGTA

Target ORF information:

RefSeq Version	NM_205055.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus AKT serine/threonine kinase 1 (AKT1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_205055.1

ORF Insert Sequence:

ATGAATGAAG TAGCGATAGT GAAGGAAGGA TGGCTCCACA AACGAGGAGA ATATATCAAA 
ACATGGAGGC CACGGTATTT TCTTTTAAAG AATGATGGCA CATTCATTGG CTACAAGGAA 
CGACCGCAAG ACGTTGACCA ACGAGAATCA CCTTTAAATA ACTTCTCAGT AGCTCAGTGC 
CAGCTGATGA AGACAGAACG ACCTAAACCA AACACATTTA TCATTAGATG CCTCCAGTGG 
ACCACAGTAA TTGAAAGAAC ATTTCATGTG GAGACTCCAG AGGAGCGGGA AGAATGGACA 
AAAGCTATCC AAACTGTTGC AGACAGCCTC AAGAAACAGG AGGAAGAGAT GATGGATTTT 
AGATCTGGTT CTCCTAGTGA TAATTCAGGT GCTGAAGAAA TGGAAGTTTC TATGACAAAG 
CCAAAACACA AAGTGACCAT GAATGAATTT GAATACCTTA AGCTACTGGG AAAAGGCACT 
TTTGGAAAGG TCATTTTAGT TAAAGAAAAA GCAACCGGAC GGTATTATGC TATGAAAATT 
CTGAAGAAGG AAGTTATTGT AGCAAAGGAT GAAGTAGCAC ACACGCTGAC AGAAAACCGT 
GTTTTACAGA ACTCACGGCA TCCATTCTTA ACAGCTTTAA AGTATTCCTT TCAGACACAC 
GATCGCTTGT GTTTTGTTAT GGAGTATGCT AACGGAGGGG AGTTGTTTTT CCATCTGTCG 
AGAGAGCGTG TATTTTCTGA AGACCGGGCG CGTTTTTATG GGGCTGAGAT TGTTTCAGCG 
CTGGATTACC TGCATTCAGA GAAGAATGTG GTGTACAGAG ATTTGAAGCT GGAAAATCTT 
ATGCTGGATA AAGACGGGCA CATAAAAATT ACAGACTTTG GACTATGTAA AGAAGGCATA 
AAAGATGGAG CAACAATGAA GACTTTCTGT GGCACTCCAG AGTATCTTGC ACCAGAGGTG 
CTGGAGGATA ATGACTATGG TCGTGCAGTG GACTGGTGGG GATTAGGAGT TGTGATGTAT 
GAAATGATGT GTGGCCGGCT CCCTTTCTAC AATCAGGACC ATGAAAAGCT CTTTGAACTC 
ATCCTTATGG AAGAGATTAG ATTTCCACGC ACTTTGTCAC CTGAAGCAAA ATCTCTCTTG 
TCAGGTTTGC TGAAGAAAGA TCCTAAGCAA AGGTTAGGAG GCGGTCCTGA TGATGCCAAG 
GAGATTATGC AGCACAAATT CTTTGCTGGC ATTGTTTGGC AAGATGTATA CGGGAAGAAG 
CTTGTACCTC CATTTAAGCC ACAAGTTACA TCTGAAACAG ATACAAGATA CTTTGATGAA 
GAATTTACAG CACAGATGAT TACAATCACT CCTCCTGACC AAGATGACAG CATGGATTGT 
GTAGACAATG AGAGAAGACC TCATTTTCCT CAGTTCTCCT ATTCAGCCAG TGGAACCGCT 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Transient activation of the PI3K/Akt pathway promotes Newcastle disease virus replication and enhances anti-apoptotic signaling responses.
Oncotarget8(14)23551-23563(2017 Apr)
Kang Y,Yuan R,Zhao X,Xiang B,Gao S,Gao P,Dai X,Feng M,Li Y,Xie P,Li Y,Gao X,Ren T

Gene expression pattern of glucose transporters in the skeletal muscles of newly hatched chicks.
Bioscience, biotechnology, and biochemistry80(7)1382-5(2016 Jul)
Shimamoto S,Ijiri D,Kawaguchi M,Nakashima K,Ohtsuka A

AKT signaling mediates IGF-I survival actions on otic neural progenitors.
PloS one7(1)e30790(2012)
Aburto MR,Magari?os M,Leon Y,Varela-Nieto I,Sanchez-Calderon H

The PI3K/Akt pathway is involved in early infection of some exogenous avian leukosis viruses.
The Journal of general virology92(Pt 7)1688-97(2011 Jul)
Feng SZ,Cao WS,Liao M

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AKT1 cDNA ORF clone, Gallus gallus(chicken)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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