Gene Symbol | Spt5 |
Entrez Gene ID | 53442 |
Full Name | CG7626 gene product from transcript CG7626-RA |
Synonyms | CG7626,DSIF,Dmel\CG7626,Dspt5,SPT5,dDSIF,dSpt5,spt5 |
Gene Type | protein-coding |
Organism | Drosophila melanogaster(fruit fly) |
Genome |
ORF » Species Summary » Drosophila melanogaster » Spt5 cDNA ORF clone
Gene Symbol | Spt5 |
Entrez Gene ID | 53442 |
Full Name | CG7626 gene product from transcript CG7626-RA |
Synonyms | CG7626,DSIF,Dmel\CG7626,Dspt5,SPT5,dDSIF,dSpt5,spt5 |
Gene Type | protein-coding |
Organism | Drosophila melanogaster(fruit fly) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_144353.4 | NP_652610.1 | Spt5 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP005021 | XP_001231045.2 |
Caenorhabditis elegans (roundworm) | spt-5 | NP_502283.1 |
Xenopus tropicalis (tropical clawed frog) | supt5h | NP_001123796.1 |
Canis lupus familiaris (dog) | SUPT5H | XP_005616644.1 |
Mus musculus (house mouse) | Supt5 | NP_038704.1 |
Gallus gallus (chicken) | SUPT5H | NP_001026555.1 |
Neurospora crassa | NCU06929 | XP_959276.2 |
SUPT5H | XP_001088495.1 | |
Bos taurus (cattle) | SUPT5H | NP_001076908.2 |
Rattus norvegicus (Norway rat) | Supt5h | NP_001100967.2 |
Schizosaccharomyces pombe (fission yeast) | spt5 | NP_593191.1 |
Arabidopsis thaliana (thale cress) | AT2G34210 | NP_180968.2 |
Oryza sativa (rice) | Os02g0772000 | NP_001173159.1 |
Saccharomyces cerevisiae (baker's yeast) | SPT5 | NP_013703.1 |
Eremothecium gossypii | AGOS_ADR187W | NP_984283.2 |
Homo sapiens (human) | SUPT5H | NP_001104490.1 |
Pan troglodytes (chimpanzee) | SUPT5H | XP_512652.3 |
Danio rerio (zebrafish) | supt5h | NP_571748.2 |
Drosophila melanogaster (fruit fly) | Spt5 | NP_652610.1 |
Kluyveromyces lactis | KLLA0B00891g | XP_451570.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_12268 | XP_003715018.1 |
Arabidopsis thaliana (thale cress) | GTA2 | NP_192575.3 |
Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
KOW5 is involved in promoter-proximal pausing through contact with the nascent RNA
Title: Identification of Regions in the Spt5 Subunit of DRB Sensitivity-inducing Factor (DSIF) That Are Involved in Promoter-proximal Pausing.
Spt5 interacts both physically and genetically with the Polycomb Group (PcG) protein Pleiohomeotic (Pho)
Title: Pleiohomeotic interacts with the core transcription elongation factor Spt5 to regulate gene expression in Drosophila.
We show that SPT5 interacts directly with MSL1 in vitro and is required downstream of MSL complex recruitment, providing the first mechanistic data corroborating the elongation model of dosage compensation.
Title: Mutations in the transcription elongation factor SPT5 disrupt a reporter for dosage compensation in Drosophila.
Spt5 acts both positively and negatively on transcription in vivo during heat shock induction.
Title: Locus-specific requirements for Spt5 in transcriptional activation and repression in Drosophila.
The following Spt5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Spt5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OFa11527 | |
Clone ID Related Accession (Same CDS sequence) | NM_144353.4 | |
Accession Version | NM_144353.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3237bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-24 | |
Organism | Drosophila melanogaster(fruit fly) | |
Product | Spt5 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033778). On Jul 15, 2014 this sequence version replaced NM_144353.3. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END## |
1 | ATGTCGGACT CGGAAGTCAG TAATATGTCG GATAGTGGCT CCGAAGATGG ATCCATTTCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_652610.1 |
CDS | 117..3353 |
Translation |
Target ORF information:
Target ORF information:
|
NM_144353.4 |
1 | ATGTCGGACT CGGAAGTCAG TAATATGTCG GATAGTGGCT CCGAAGATGG ATCCATTTCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data. |
Gene Model Annotations for Drosophila melanogaster: The Rule-Benders. |
Sequence finishing and mapping of Drosophila melanogaster heterochromatin. |
The Release 5.1 annotation of Drosophila melanogaster heterochromatin. |
Combined evidence annotation of transposable elements in genome sequences. |