Dr cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	Dr
Entrez Gene ID	45285
Full Name	Drop
Synonyms	153515_at,99B,CG1897,Dmel\CG1897,Dr/msh,Msh,Msx,l(3)FA30,ltt,msh,msh-1,msh1
General protein information	Preferred Names Drop Names CG1897 gene product from transcript CG1897-RA CG1897-PA Dr-PA Dr-distal drop lottchen muscle segment homeobox muscle specific homeobox muscle-specific homeodomain muscle-specific homeodomain 1
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 3R Map Location: 99B3-99B3\|3-99.2 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_057976.3	NP_477324.1	drop

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

cross-repression between Ind and Msh stabilizes the border between intermediate and dorsal tritocerebrum and deutocerebrum, and that both transcription factors are competent to inhibit vnd expression
Title: Role of en and novel interactions between msh, ind, and vnd in dorsoventral patterning of the Drosophila brain and ventral nerve cord.

expression is expanded ventrally in ind mutant embryos and Ind protein directly and specifically bound to the msh regulatory DNA, and this interaction was required to limit the ventral boundary of msh expression.
Title: Ind represses msh expression in the intermediate column of the Drosophila neuroectoderm, through direct interaction with upstream regulatory DNA.

Data show that expression of gene msh is invloved in dorsoventral regionalization within the developing brain and truncal nervous system in Drosophilia.
Title: Dorsoventral patterning of the brain: a comparative approach.

Mutual repression between msh and Iro-C is an essential component of the boundary between body wall and wing in Drosophila.
Title: Mutual repression between msh and Iro-C is an essential component of the boundary between body wall and wing in Drosophila.

The following Dr gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dr cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa06878	NM_057976.3 Latest version!	Drosophila melanogaster drop (Dr), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Dr ( NM_057976.3 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_477324.1 Drosophila melanogaster drop (Dr), mRNA.

Price & Availability↑

CloneID	OFa06878
Clone ID Related Accession (Same CDS sequence)	NM_057976.3
Accession Version	NM_057976.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1548bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	drop
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033777). On Jul 15, 2014 this sequence version replaced NM_057976.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGTTAAAGC TCAGCCCAGC GAGCATGACA GTTACAGGTC TGCGCCAGAC GATGACCAGT 
CCCACGGTGC CGCCGAGCAG TAACACTCCC GCGGGTAACC TCATCATCAC CAGCAGCAGT 
AGCAACAGCG GCAGCAACAG CGGCAGCAAC ATGAGCAGCG GCAACATGAC CAGCAGCAAC 
CTGACCAACC TGAGTCCTAG CCACCCGGCT GGCCTGAATG CCCTGGCCAG TCCCACCTCG 
CCGTCGGCAC TGCTGCTGGC CCATCAGCAG CATCTGCTGC AGCAGCACCA GCAACACCAG 
CAGCAGCAGC AACAGCAGCA GCAGGCGGCG GCGCTCCAGC TGGCCGCAGT GCATCCGCCG 
GCCCACCATC TGCACAAGAC CACCTCCCGA CTGAGCAACT TTAGTGTGGC CTCTCTCCTG 
GCGGACACGA GGCCCAGAAC GCCACCCAAC CAGGCGGCGG ATGGACCCCA GAACCTGACC 
AGTTCGGCGG CCACCTCGCC CATCTCCCAG GCCAGCAGCA CGCCGCCGCC TCCGCCGGCC 
AGTGCGGCCG CCCAAGTTCC CGCCAACACC TTCCATCCCG CCGCCGTCGC GCACCACGCC 
CACTTGCTGC AGGCCGCCCA CGCGGCTGCG GCGGCACATG CCCAGCACCA GGCGATGGCC 
GCCCAGCTGC GCCAACAGCA GCAGCAGGCG GACGCCCGGG CCAACTCGCC ACCCGCCTCC 
ACGAGTTCCA CGCCCAGCTC CACGCCACTG GGATCCGCAC TGGGATCGCA GGGCAATGTG 
GCCTCCACTC CCGCCAAAAA TGAACGCCAT TCGCCGCTGG GCAGCCACAC GGACTCCGAG 
CTGGAGTACG ACGAGGAGAT GCTGCAGGAC CACGAGGCCG ATCACGACGA GGAGGAGGAC 
TCCATTGTGG ATATCGAGGA CATGAACGCC GACGACTCGC CGCGCTCCAC GCCCGACGGC 
CTCGACGGCA GCGGCAAGTC GCTGGAATCG CCGCACGGTC CGCCGCCGGG CTCTCACATG 
CAATCCACGA TACTTTCCCC GGCGGCCCTG GCCTCCGGTC ATGTGCCCAT CCGCCCGACC 
CCCTTCAGTG CACTGGCCGC CGCGGCGGTG GCCTGGACGG GAATGGGCGG TGGAGTTCCG 
TGGCCAGGAA CCAGACAAAT GCCGCCCTTC GGACCGCCTG GCATGTTTCC GGGAGCAGGA 
TTCGGTGGAG ATGCCAACGA ACCGCCGCGG ATCAAGTGCA ACCTGCGGAA GCACAAGCCC 
AACCGGAAGC CCCGCACCCC CTTCACAACA CAGCAGCTGC TCTCGCTGGA GAAGAAGTTC 
CGGGAGAAGC AGTACCTGAG CATCGCCGAA CGGGCGGAGT TCTCCTCCTC GCTGCGGCTG 
ACGGAGACGC AGGTGAAGAT CTGGTTCCAG AACCGAAGGG CCAAGGCCAA GCGTCTCCAG 
GAGGCCGAGA TCGAGAAGAT CAAGATGGCG GCGCTGGGCC GAGGAGCACC TGGTGCCCAG 
TGGGCCATGG CCGGGTACTT CCATCCGAGC CTGATGCACC TGGGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_477324.1
CDS	251..1798
Translation	MLKLSPASMTVTGLRQTMTSPTVPPSSNTPAGNLIITSSSSNSGSNSGSNMSSGNMTSSNLTNLSPSHPAGLNALASPTSPSALLLAHQQHLLQQHQQHQQQQQQQQQAAALQLAAVHPPAHHLHKTTSRLSNFSVASLLADTRPRTPPNQAADGPQNLTSSAATSPISQASSTPPPPPASAAAQVPANTFHPAAVAHHAHLLQAAHAAAAAHAQHQAMAAQLRQQQQQADARANSPPASTSSTPSSTPLGSALGSQGNVASTPAKNERHSPLGSHTDSELEYDEEMLQDHEADHDEEEDSIVDIEDMNADDSPRSTPDGLDGSGKSLESPHGPPPGSHMQSTILSPAALASGHVPIRPTPFSALAAAAVAWTGMGGGVPWPGTRQMPPFGPPGMFPGAGFGGDANEPPRIKCNLRKHKPNRKPRTPFTTQQLLSLEKKFREKQYLSIAERAEFSSSLRLTETQVKIWFQNRRAKAKRLQEAEIEKIKMAALGRGAPGAQWAMAGYFHPSLMHLG

Target ORF information:

RefSeq Version	NM_057976.3
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster drop (Dr), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_057976.3

ORF Insert Sequence:

ATGTTAAAGC TCAGCCCAGC GAGCATGACA GTTACAGGTC TGCGCCAGAC GATGACCAGT 
CCCACGGTGC CGCCGAGCAG TAACACTCCC GCGGGTAACC TCATCATCAC CAGCAGCAGT 
AGCAACAGCG GCAGCAACAG CGGCAGCAAC ATGAGCAGCG GCAACATGAC CAGCAGCAAC 
CTGACCAACC TGAGTCCTAG CCACCCGGCT GGCCTGAATG CCCTGGCCAG TCCCACCTCG 
CCGTCGGCAC TGCTGCTGGC CCATCAGCAG CATCTGCTGC AGCAGCACCA GCAACACCAG 
CAGCAGCAGC AACAGCAGCA GCAGGCGGCG GCGCTCCAGC TGGCCGCAGT GCATCCGCCG 
GCCCACCATC TGCACAAGAC CACCTCCCGA CTGAGCAACT TTAGTGTGGC CTCTCTCCTG 
GCGGACACGA GGCCCAGAAC GCCACCCAAC CAGGCGGCGG ATGGACCCCA GAACCTGACC 
AGTTCGGCGG CCACCTCGCC CATCTCCCAG GCCAGCAGCA CGCCGCCGCC TCCGCCGGCC 
AGTGCGGCCG CCCAAGTTCC CGCCAACACC TTCCATCCCG CCGCCGTCGC GCACCACGCC 
CACTTGCTGC AGGCCGCCCA CGCGGCTGCG GCGGCACATG CCCAGCACCA GGCGATGGCC 
GCCCAGCTGC GCCAACAGCA GCAGCAGGCG GACGCCCGGG CCAACTCGCC ACCCGCCTCC 
ACGAGTTCCA CGCCCAGCTC CACGCCACTG GGATCCGCAC TGGGATCGCA GGGCAATGTG 
GCCTCCACTC CCGCCAAAAA TGAACGCCAT TCGCCGCTGG GCAGCCACAC GGACTCCGAG 
CTGGAGTACG ACGAGGAGAT GCTGCAGGAC CACGAGGCCG ATCACGACGA GGAGGAGGAC 
TCCATTGTGG ATATCGAGGA CATGAACGCC GACGACTCGC CGCGCTCCAC GCCCGACGGC 
CTCGACGGCA GCGGCAAGTC GCTGGAATCG CCGCACGGTC CGCCGCCGGG CTCTCACATG 
CAATCCACGA TACTTTCCCC GGCGGCCCTG GCCTCCGGTC ATGTGCCCAT CCGCCCGACC 
CCCTTCAGTG CACTGGCCGC CGCGGCGGTG GCCTGGACGG GAATGGGCGG TGGAGTTCCG 
TGGCCAGGAA CCAGACAAAT GCCGCCCTTC GGACCGCCTG GCATGTTTCC GGGAGCAGGA 
TTCGGTGGAG ATGCCAACGA ACCGCCGCGG ATCAAGTGCA ACCTGCGGAA GCACAAGCCC 
AACCGGAAGC CCCGCACCCC CTTCACAACA CAGCAGCTGC TCTCGCTGGA GAAGAAGTTC 
CGGGAGAAGC AGTACCTGAG CATCGCCGAA CGGGCGGAGT TCTCCTCCTC GCTGCGGCTG 
ACGGAGACGC AGGTGAAGAT CTGGTTCCAG AACCGAAGGG CCAAGGCCAA GCGTCTCCAG 
GAGGCCGAGA TCGAGAAGAT CAAGATGGCG GCGCTGGGCC GAGGAGCACC TGGTGCCCAG 
TGGGCCATGG CCGGGTACTT CCATCCGAGC CTGATGCACC TGGGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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Dr cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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