cv-2 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	cv-2
Entrez Gene ID	45280
Full Name	crossveinless 2
Synonyms	BMPER,CG15671,CT35855,CV2,Cv 2,Cv-2,Cv2,Dmel\CG15671,cv 2
General protein information	Preferred Names crossveinless 2 Names CG15671 gene product from transcript CG15671-RA CG15671-PA crossveinless-2 cv-2-PA
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 2R Map Location: 57D12-57E1\|2-96.2 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_080070.4	NP_524809.2	crossveinless 2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	BMPER	XP_519036.3
Mus musculus (house mouse)	Bmper	NP_082748.1
Danio rerio (zebrafish)	bmper	NP_001018323.1
Rattus norvegicus (Norway rat)	Bmper	NP_001129271.1
Drosophila melanogaster (fruit fly)	cv-2	NP_524809.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006168	XP_316228.4
Homo sapiens (human)	BMPER	NP_597725.1
	BMPER	XP_001105988.1
Gallus gallus (chicken)	BMPER	NP_001007081.1
Canis lupus familiaris (dog)	BMPER	XP_532513.2
Bos taurus (cattle)	BMPER	NP_001071465.1
Xenopus tropicalis (tropical clawed frog)	bmper	NP_001037867.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The bone morphogenetic protein- binding protein Cv-2 negatively regulates bone morphogenetic protein signaling.
Title: A genetic network conferring canalization to a bistable patterning system in Drosophila.

Cv-2 is a short-range, concentration-dependent, biphasic modulator of BMP signaling.
Title: The BMP-binding protein Crossveinless 2 is a short-range, concentration-dependent, biphasic modulator of BMP signaling in Drosophila.

The following cv-2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the cv-2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa11389	NM_080070.4 Latest version!	Drosophila melanogaster crossveinless 2 (cv-2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$426.30 $609.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

cv-2 ( NM_080070.4 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_524809.2 Drosophila melanogaster crossveinless 2 (cv-2), mRNA.

Price & Availability↑

CloneID	OFa11389
Clone ID Related Accession (Same CDS sequence)	NM_080070.4
Accession Version	NM_080070.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2256bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	crossveinless 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033778). On Jul 15, 2014 this sequence version replaced NM_080070.3. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGTGTTGCC AATCAAGTGG CCAGTGGAAA TTTCCTGCGC AGCAGCCTCG AAAATCTTTG 
GCGTCAAGGC GGCGCCACAC GGGATTTCGC CCAAGCACCC AGCTCCTGAT CCTCATCGCA 
GTCCTGCTGG CCCTGCTGCA AGGACGAACA GTCGACGCCG GGGCGGGAGA TAGTCTATCG 
GGCGTCCGGC AATCCTGCTC GAATGAGGGA GAAGAAGTCC AACTGAAGAA CCAGCCGCAG 
ATTTTCACCT GCTTCAAGTG CGAATGCCAG AACGGATTCG TGAATTGCCG AGATACTTGT 
CCACCAGTCA ATGACTGTTA CATTCTGGAT AAGTCGAATG GAACTTGCTG CCGCAGGTGC 
AAGGGTTGCT CTTTTCGTGG CATGTCGTAT GAGAGTGGCT CGGAGTGGAA CGATCCGGAG 
GATCCCTGCA AGACGTACAA GTGCGTGGCC ACCGTGGTCA CCGAGACGAT CCAGAAGTGC 
TACTCGCAGT GCGACAACAA CCAGTTACAG CCACCACGAC CGGGCGAATG CTGTCCCACC 
TGTCAGGGTT GCAAGATCAA CGGACAGACG GTGGCCGAGG GCCACGAGGT GGACGCCTCC 
ATTGACGACC GCTGTCTGGT CTGCCAGTGC CGCGGGACGC AGTTGACCTG TTCCAAGAAG 
ACATGCCCGG TGCTACCGTG TCCCATGTCC AAGCAGATCA AGCGTCCGGA TGAGTGCTGT 
CCGCGCTGCC CGCAGAACCA CAGTTTTCTA CCTGTTCCAG GCAAATGCCT CTTCAACAAA 
AGCGTTTATC CGGAGAAGAC GCAGTTTATG CCGGACAGGT GTACGAACTG CACCTGCCTG 
AACGGCACCT CCGTGTGCCA GCGACCCACC TGCCCGATCT TGGAGTGCGC TCCCGAATTC 
CAGGAGCCAG ATGGCTGCTG TCCACGCTGT GCGGTGGCCG AAGTGCGGAG CGAGTGCAGC 
TTGGATGGGA TTGTGTACCA GAACAACGAG ACGTGGGACA TGGGGCCGTG TCGCAGCTGC 
CGGTGCAATG GTGGAACCAT CCGGTGTGCC CAGATGCGCT GTCCGGCGGT CAAGTGCCGA 
GCGAACGAGG AGCTGAAACA GCCGCCGGGA GAATGTTGCC AACGGTGCGT GGAGACGGCG 
GGCACGTGCA CCGTCTTCGG AGATCCTCAC TTCCGTACCT TCGATGGCAA GTTCTTCAGC 
TTCCAGGGCA GCTGCAAGTA CCTCCTGGCG TCCGACTGTA TGGGCAAAAC CTTCCACATC 
CGGCTGACGA ACGAGGGACG CGGCACACGG CGTGCCAGCT GGGCCAAAAC GGTGACCCTA 
AGTCTGCGAA ACTTGAAAGT CAATCTCGGC CAGCGAATGC GGGTCAAGGT GAATGGAACC 
AGGGTAACGT TGCCCTACTT CGTTGTAGCC GGTGGCCAGA ACGTGACGAT TGAGCGCTTG 
GCCAACGGAG GAGCGGTGAT GCTGAGATCG GAAATGGGCT TGACCCTGGA GTGGAATGGA 
GCTGGCTTCC TGCAGGTTTC GGTGCCGGCG AAATTCAAGA AAAGACTGTG TGGTCTATGT 
GGCAACTTCA ACGGCAGTTC GCGGGACGAT CTCACGGGGA AGGATGGACG GAGCCACGGG 
GACGACGAGG TCTGGCACTT TGCCAATTCC TGGAAGGTGG GTGGCCCCAA GTCCTGTTCC 
CGCAAGCGTG AATTCCTGGC TGCCACGCCC ACCTGCGACA AGCGCAAATC GAACTTCTAC 
TGCCACCCAC TGAGTGTTCC CGCGCTCTTC GGCGAGTGCA ACGAGCGACT GAATCCGGAG 
AACTACAAGG CCGCCTGCCG GATGGACGTG TGTGAGTGTC CATCGGGCGA CTGTCACTGC 
GACAGCTTTG CGGCGTACGC CCACGAGTGC CGGCGACTCG GAGTCCAGTT GCCGGACTGG 
AGGAGCGCTA CCAATTGCCC CGCAGGCTGG CGTCGCAATG CCACGTTGTC CAGCTTCAAG 
GGCAACCAGT TCTACGGTGA TCCCAGCTTC AGCCGAATGA AGGGTCGGCG ACAGAAGAAC 
CACCAGCTGC GACTGCAGCT GCAGCAGGAG CAGCAGCAGC GGAGCAAACA GGGCCAAAAG 
GGGCGGCACA AGCCGGGTGG CCACAACCAG CTGGACAGGC AGGGCCACAA CGGTCTGGAC 
AAGGATCAGC TGCAGAAGGA GTTCATCCTG AAGCATGTGC CCAGCAGTTT CCTCTATCCG 
CGTGCGCCGG ATCGCACGCC GCCGCCCCTC CACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_524809.2
CDS	1083..3338
Translation	MCCQSSGQWKFPAQQPRKSLASRRRHTGFRPSTQLLILIAVLLALLQGRTVDAGAGDSLSGVRQSCSNEGEEVQLKNQPQIFTCFKCECQNGFVNCRDTCPPVNDCYILDKSNGTCCRRCKGCSFRGMSYESGSEWNDPEDPCKTYKCVATVVTETIQKCYSQCDNNQLQPPRPGECCPTCQGCKINGQTVAEGHEVDASIDDRCLVCQCRGTQLTCSKKTCPVLPCPMSKQIKRPDECCPRCPQNHSFLPVPGKCLFNKSVYPEKTQFMPDRCTNCTCLNGTSVCQRPTCPILECAPEFQEPDGCCPRCAVAEVRSECSLDGIVYQNNETWDMGPCRSCRCNGGTIRCAQMRCPAVKCRANEELKQPPGECCQRCVETAGTCTVFGDPHFRTFDGKFFSFQGSCKYLLASDCMGKTFHIRLTNEGRGTRRASWAKTVTLSLRNLKVNLGQRMRVKVNGTRVTLPYFVVAGGQNVTIERLANGGAVMLRSEMGLTLEWNGAGFLQVSVPAKFKKRLCGLCGNFNGSSRDDLTGKDGRSHGDDEVWHFANSWKVGGPKSCSRKREFLAATPTCDKRKSNFYCHPLSVPALFGECNERLNPENYKAACRMDVCECPSGDCHCDSFAAYAHECRRLGVQLPDWRSATNCPAGWRRNATLSSFKGNQFYGDPSFSRMKGRRQKNHQLRLQLQQEQQQRSKQGQKGRHKPGGHNQLDRQGHNGLDKDQLQKEFILKHVPSSFLYPRAPDRTPPPLH

Target ORF information:

RefSeq Version	NM_080070.4
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster crossveinless 2 (cv-2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_080070.4

ORF Insert Sequence:

ATGTGTTGCC AATCAAGTGG CCAGTGGAAA TTTCCTGCGC AGCAGCCTCG AAAATCTTTG 
GCGTCAAGGC GGCGCCACAC GGGATTTCGC CCAAGCACCC AGCTCCTGAT CCTCATCGCA 
GTCCTGCTGG CCCTGCTGCA AGGACGAACA GTCGACGCCG GGGCGGGAGA TAGTCTATCG 
GGCGTCCGGC AATCCTGCTC GAATGAGGGA GAAGAAGTCC AACTGAAGAA CCAGCCGCAG 
ATTTTCACCT GCTTCAAGTG CGAATGCCAG AACGGATTCG TGAATTGCCG AGATACTTGT 
CCACCAGTCA ATGACTGTTA CATTCTGGAT AAGTCGAATG GAACTTGCTG CCGCAGGTGC 
AAGGGTTGCT CTTTTCGTGG CATGTCGTAT GAGAGTGGCT CGGAGTGGAA CGATCCGGAG 
GATCCCTGCA AGACGTACAA GTGCGTGGCC ACCGTGGTCA CCGAGACGAT CCAGAAGTGC 
TACTCGCAGT GCGACAACAA CCAGTTACAG CCACCACGAC CGGGCGAATG CTGTCCCACC 
TGTCAGGGTT GCAAGATCAA CGGACAGACG GTGGCCGAGG GCCACGAGGT GGACGCCTCC 
ATTGACGACC GCTGTCTGGT CTGCCAGTGC CGCGGGACGC AGTTGACCTG TTCCAAGAAG 
ACATGCCCGG TGCTACCGTG TCCCATGTCC AAGCAGATCA AGCGTCCGGA TGAGTGCTGT 
CCGCGCTGCC CGCAGAACCA CAGTTTTCTA CCTGTTCCAG GCAAATGCCT CTTCAACAAA 
AGCGTTTATC CGGAGAAGAC GCAGTTTATG CCGGACAGGT GTACGAACTG CACCTGCCTG 
AACGGCACCT CCGTGTGCCA GCGACCCACC TGCCCGATCT TGGAGTGCGC TCCCGAATTC 
CAGGAGCCAG ATGGCTGCTG TCCACGCTGT GCGGTGGCCG AAGTGCGGAG CGAGTGCAGC 
TTGGATGGGA TTGTGTACCA GAACAACGAG ACGTGGGACA TGGGGCCGTG TCGCAGCTGC 
CGGTGCAATG GTGGAACCAT CCGGTGTGCC CAGATGCGCT GTCCGGCGGT CAAGTGCCGA 
GCGAACGAGG AGCTGAAACA GCCGCCGGGA GAATGTTGCC AACGGTGCGT GGAGACGGCG 
GGCACGTGCA CCGTCTTCGG AGATCCTCAC TTCCGTACCT TCGATGGCAA GTTCTTCAGC 
TTCCAGGGCA GCTGCAAGTA CCTCCTGGCG TCCGACTGTA TGGGCAAAAC CTTCCACATC 
CGGCTGACGA ACGAGGGACG CGGCACACGG CGTGCCAGCT GGGCCAAAAC GGTGACCCTA 
AGTCTGCGAA ACTTGAAAGT CAATCTCGGC CAGCGAATGC GGGTCAAGGT GAATGGAACC 
AGGGTAACGT TGCCCTACTT CGTTGTAGCC GGTGGCCAGA ACGTGACGAT TGAGCGCTTG 
GCCAACGGAG GAGCGGTGAT GCTGAGATCG GAAATGGGCT TGACCCTGGA GTGGAATGGA 
GCTGGCTTCC TGCAGGTTTC GGTGCCGGCG AAATTCAAGA AAAGACTGTG TGGTCTATGT 
GGCAACTTCA ACGGCAGTTC GCGGGACGAT CTCACGGGGA AGGATGGACG GAGCCACGGG 
GACGACGAGG TCTGGCACTT TGCCAATTCC TGGAAGGTGG GTGGCCCCAA GTCCTGTTCC 
CGCAAGCGTG AATTCCTGGC TGCCACGCCC ACCTGCGACA AGCGCAAATC GAACTTCTAC 
TGCCACCCAC TGAGTGTTCC CGCGCTCTTC GGCGAGTGCA ACGAGCGACT GAATCCGGAG 
AACTACAAGG CCGCCTGCCG GATGGACGTG TGTGAGTGTC CATCGGGCGA CTGTCACTGC 
GACAGCTTTG CGGCGTACGC CCACGAGTGC CGGCGACTCG GAGTCCAGTT GCCGGACTGG 
AGGAGCGCTA CCAATTGCCC CGCAGGCTGG CGTCGCAATG CCACGTTGTC CAGCTTCAAG 
GGCAACCAGT TCTACGGTGA TCCCAGCTTC AGCCGAATGA AGGGTCGGCG ACAGAAGAAC 
CACCAGCTGC GACTGCAGCT GCAGCAGGAG CAGCAGCAGC GGAGCAAACA GGGCCAAAAG 
GGGCGGCACA AGCCGGGTGG CCACAACCAG CTGGACAGGC AGGGCCACAA CGGTCTGGAC 
AAGGATCAGC TGCAGAAGGA GTTCATCCTG AAGCATGTGC CCAGCAGTTT CCTCTATCCG 
CGTGCGCCGG ATCGCACGCC GCCGCCCCTC CACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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cv-2 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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