cl cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	cl
Entrez Gene ID	43938
Full Name	clot
Synonyms	BcDNA:RE06767,CG11024,Dmel\CG11024
General protein information	Preferred Names clot Names CG11024 gene product from transcript CG11024-RB CG11024-PA CG11024-PB CG11024-PC cl-PA cl-PB cl-PC
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 2L Map Location: 25E5-25E5

mRNA and Protein(s)

mRNA	Protein	Name
NM_001273170.1	NP_001260099.1	clot, isoform C
NM_135086.4	NP_608930.1	clot, isoform A
NM_001273169.1	NP_001260098.1	clot, isoform B

Pathways from BioSystems

Homologies

Homo sapiens (human)	TXNDC17	NP_116120.1
	TXNDC17	XP_001103113.1
Bos taurus (cattle)	TXNDC17	NP_001192750.1
Pan troglodytes (chimpanzee)	TXNDC17	XP_511988.2
Anopheles gambiae (African malaria mosquito)	GRX3	XP_318823.2
Danio rerio (zebrafish)	txndc17	NP_001003456.1
Mus musculus (house mouse)	Txndc17	NP_080835.1
Xenopus tropicalis (tropical clawed frog)	txndc17	XP_004911789.1
Rattus norvegicus (Norway rat)	Txndc17	NP_001099275.1
Gallus gallus (chicken)	TXNDC17	XP_415925.1
Drosophila melanogaster (fruit fly)	cl	NP_001260098.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Clot protein is an essential component of a glutathione redox system required for the final step in the biosynthetic pathway for drosopterins. Cloning, molecular organization and sequence alterations associated with the alleles cl(1) and cl(2)
Title: The clot gene of Drosophila melanogaster encodes a conserved member of the thioredoxin-like protein superfamily.

The following cl gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the cl cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OFa15181	NM_135086.4 Latest version!	Drosophila melanogaster clot (cl), transcript variant A, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OFa15181	NM_001273169.1 Latest version!	Drosophila melanogaster clot (cl), transcript variant B, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OFa15181	NM_001273170.1 Latest version!	Drosophila melanogaster clot (cl), transcript variant C, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

cl ( NM_001273170.1 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_001260099.1 Drosophila melanogaster clot (cl), transcript variant C, mRNA.

Price & Availability↑

CloneID	OFa15181
Clone ID Related Accession (Same CDS sequence)	NM_001273170.1 , NM_135086.4 , NM_001273169.1
Accession Version	NM_001273170.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 381bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	clot, isoform C
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033779). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGTGGTCA CACACAACGT CAAGGGATAC GATGAGTTCA CCAAAAAGAT GGAGGAACTG 
GAGAACGGCG ACGAGCCGGT CCACGTCCTC TTCAGTGGCG GCAAGGACGA GAAAGGAGAG 
AGCTGGTGCC CCTACTGCGT CAAGGCGGAG CCGGTGATAC ACGATGCGCT GAAGAAGGCC 
CCGGGCAACT CGCACTTCGT GCATGTGGAT GTGGGCGAGC GGGCATACTG GAAGGATTTG 
AACTGCCCCT TCCGCAAGGA TCCCAACACG CATCTGATCT TCTTGCCCAC TCTGTTGCGC 
TGGAAGCGGC CACAGCGTCT GGATGGCGAG CGCTGCTCCA ATCAGGATCT CGTCGAGATG 
ATGTTCGAGG ATGAGGATTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001260099.1
CDS	201..581
Translation	MVVTHNVKGYDEFTKKMEELENGDEPVHVLFSGGKDEKGESWCPYCVKAEPVIHDALKKAPGNSHFVHVDVGERAYWKDLNCPFRKDPNTHLIFLPTLLRWKRPQRLDGERCSNQDLVEMMFEDED

Target ORF information:

RefSeq Version	NM_001273170.1
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster clot (cl), transcript variant C, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001273170.1

ORF Insert Sequence:

ATGGTGGTCA CACACAACGT CAAGGGATAC GATGAGTTCA CCAAAAAGAT GGAGGAACTG 
GAGAACGGCG ACGAGCCGGT CCACGTCCTC TTCAGTGGCG GCAAGGACGA GAAAGGAGAG 
AGCTGGTGCC CCTACTGCGT CAAGGCGGAG CCGGTGATAC ACGATGCGCT GAAGAAGGCC 
CCGGGCAACT CGCACTTCGT GCATGTGGAT GTGGGCGAGC GGGCATACTG GAAGGATTTG 
AACTGCCCCT TCCGCAAGGA TCCCAACACG CATCTGATCT TCTTGCCCAC TCTGTTGCGC 
TGGAAGCGGC CACAGCGTCT GGATGGCGAG CGCTGCTCCA ATCAGGATCT CGTCGAGATG 
ATGTTCGAGG ATGAGGATTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

cl ( NM_135086.4 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_608930.1 Drosophila melanogaster clot (cl), transcript variant A, mRNA.

Price & Availability↑

CloneID	OFa15181
Clone ID Related Accession (Same CDS sequence)	NM_001273170.1 , NM_135086.4 , NM_001273169.1
Accession Version	NM_135086.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 381bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	clot, isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033779). On Jul 15, 2014 this sequence version replaced NM_135086.3. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGTGGTCA CACACAACGT CAAGGGATAC GATGAGTTCA CCAAAAAGAT GGAGGAACTG 
GAGAACGGCG ACGAGCCGGT CCACGTCCTC TTCAGTGGCG GCAAGGACGA GAAAGGAGAG 
AGCTGGTGCC CCTACTGCGT CAAGGCGGAG CCGGTGATAC ACGATGCGCT GAAGAAGGCC 
CCGGGCAACT CGCACTTCGT GCATGTGGAT GTGGGCGAGC GGGCATACTG GAAGGATTTG 
AACTGCCCCT TCCGCAAGGA TCCCAACACG CATCTGATCT TCTTGCCCAC TCTGTTGCGC 
TGGAAGCGGC CACAGCGTCT GGATGGCGAG CGCTGCTCCA ATCAGGATCT CGTCGAGATG 
ATGTTCGAGG ATGAGGATTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_608930.1
CDS	142..522
Translation	MVVTHNVKGYDEFTKKMEELENGDEPVHVLFSGGKDEKGESWCPYCVKAEPVIHDALKKAPGNSHFVHVDVGERAYWKDLNCPFRKDPNTHLIFLPTLLRWKRPQRLDGERCSNQDLVEMMFEDED

Target ORF information:

RefSeq Version	NM_135086.4
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster clot (cl), transcript variant A, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_135086.4

ORF Insert Sequence:

ATGGTGGTCA CACACAACGT CAAGGGATAC GATGAGTTCA CCAAAAAGAT GGAGGAACTG 
GAGAACGGCG ACGAGCCGGT CCACGTCCTC TTCAGTGGCG GCAAGGACGA GAAAGGAGAG 
AGCTGGTGCC CCTACTGCGT CAAGGCGGAG CCGGTGATAC ACGATGCGCT GAAGAAGGCC 
CCGGGCAACT CGCACTTCGT GCATGTGGAT GTGGGCGAGC GGGCATACTG GAAGGATTTG 
AACTGCCCCT TCCGCAAGGA TCCCAACACG CATCTGATCT TCTTGCCCAC TCTGTTGCGC 
TGGAAGCGGC CACAGCGTCT GGATGGCGAG CGCTGCTCCA ATCAGGATCT CGTCGAGATG 
ATGTTCGAGG ATGAGGATTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

cl ( NM_001273169.1 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_001260098.1 Drosophila melanogaster clot (cl), transcript variant B, mRNA.

Price & Availability↑

CloneID	OFa15181
Clone ID Related Accession (Same CDS sequence)	NM_001273170.1 , NM_135086.4 , NM_001273169.1
Accession Version	NM_001273169.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 381bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	clot, isoform B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033779). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGTGGTCA CACACAACGT CAAGGGATAC GATGAGTTCA CCAAAAAGAT GGAGGAACTG 
GAGAACGGCG ACGAGCCGGT CCACGTCCTC TTCAGTGGCG GCAAGGACGA GAAAGGAGAG 
AGCTGGTGCC CCTACTGCGT CAAGGCGGAG CCGGTGATAC ACGATGCGCT GAAGAAGGCC 
CCGGGCAACT CGCACTTCGT GCATGTGGAT GTGGGCGAGC GGGCATACTG GAAGGATTTG 
AACTGCCCCT TCCGCAAGGA TCCCAACACG CATCTGATCT TCTTGCCCAC TCTGTTGCGC 
TGGAAGCGGC CACAGCGTCT GGATGGCGAG CGCTGCTCCA ATCAGGATCT CGTCGAGATG 
ATGTTCGAGG ATGAGGATTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001260098.1
CDS	216..596
Translation	MVVTHNVKGYDEFTKKMEELENGDEPVHVLFSGGKDEKGESWCPYCVKAEPVIHDALKKAPGNSHFVHVDVGERAYWKDLNCPFRKDPNTHLIFLPTLLRWKRPQRLDGERCSNQDLVEMMFEDED

Target ORF information:

RefSeq Version	NM_001273169.1
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster clot (cl), transcript variant B, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001273169.1

ORF Insert Sequence:

ATGGTGGTCA CACACAACGT CAAGGGATAC GATGAGTTCA CCAAAAAGAT GGAGGAACTG 
GAGAACGGCG ACGAGCCGGT CCACGTCCTC TTCAGTGGCG GCAAGGACGA GAAAGGAGAG 
AGCTGGTGCC CCTACTGCGT CAAGGCGGAG CCGGTGATAC ACGATGCGCT GAAGAAGGCC 
CCGGGCAACT CGCACTTCGT GCATGTGGAT GTGGGCGAGC GGGCATACTG GAAGGATTTG 
AACTGCCCCT TCCGCAAGGA TCCCAACACG CATCTGATCT TCTTGCCCAC TCTGTTGCGC 
TGGAAGCGGC CACAGCGTCT GGATGGCGAG CGCTGCTCCA ATCAGGATCT CGTCGAGATG 
ATGTTCGAGG ATGAGGATTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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cl cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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