amx cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	amx
Entrez Gene ID	43869
Full Name	almondex
Synonyms	BcDNA:GH02974,CG12127,Dmel\CG12127,fs(1)amx
General protein information	Preferred Names almondex Names CG12127 gene product from transcript CG12127-RA CG12127-PA CG12127-PB amx-PA amx-PB
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: X Map Location: 8D2-8D2

mRNA and Protein(s)

mRNA	Protein	Name
NM_079905.3	NP_524644.1	almondex, isoform A
NM_001258662.2	NP_001245591.1	almondex, isoform B

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	TM2D3	XP_001143945.1
Rattus norvegicus (Norway rat)	Tm2d3	NP_001099737.1
Caenorhabditis elegans (roundworm)	C41D11.9	NP_491372.1
Gallus gallus (chicken)	TM2D3	XP_413775.3
Danio rerio (zebrafish)	tm2d3	NP_001092734.1
Drosophila melanogaster (fruit fly)	amx	NP_001245591.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006109	XP_316171.4
Canis lupus familiaris (dog)	TM2D3	XP_005618336.1
Mus musculus (house mouse)	Tm2d3	NP_835157.1
Homo sapiens (human)	TM2D3	NP_510883.2
	TM2D3	XP_001086181.2
Xenopus tropicalis (tropical clawed frog)	tm2d3	XP_002937906.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

we found that human TM2D3 expressed under the control of endogenous Drosophila amx regulatory elements is capable of rescuing the embryonic neurogenic phenotype, indicating that Amx and TM2D3 are orthologs and have conserved molecular functions in vivo
Title: Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease.

Our molecular data reveal that amx is ubiquitously expressed and encodes a conserved putative transmembrane protein, composed of several domains that are differently required for amx function in the fly.
Title: Implication of the Drosophila beta-amyloid peptide binding-like protein AMX in Notch signaling during early neurogenesis.

The following amx gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the amx cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa02288	NM_079905.3 Latest version!	Drosophila melanogaster almondex (amx), transcript variant A, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
OFa02288	NM_001258662.2 Latest version!	Drosophila melanogaster almondex (amx), transcript variant B, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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2-4 Clone	40% OFF
5 or more Clone	50% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

amx ( NM_079905.3 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_524644.1 Drosophila melanogaster almondex (amx), transcript variant A, mRNA.

Price & Availability↑

CloneID	OFa02288
Clone ID Related Accession (Same CDS sequence)	NM_079905.3 , NM_001258662.2
Accession Version	NM_079905.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 855bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	almondex, isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). On Dec 17, 2009 this sequence version replaced NM_079905.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGAGGCTCC AACGACAGTG CATTGTGGTC AACATGCGAT CGGCCATTGT CCTGATCATG 
ATCTTCGTGC TGACGGGGAT CAGGAACAGC GAAACGGCCA GCGGTGGCAA CCAGATGGAC 
TTATCGGACT CAAAAGGCGA TCACAAGGAT AACAGCAATG CGAGCAATGG CAATGGAAAT 
GCCAACGATA ACGAGGTGTA TGTGCCGCCC CTGGTGTCCA GCATGGTGGC CAAGAGTGGA 
GGAGGTGCCG GTGGACTCCT GGACAACATA ACCGCCTACA GCAGCAGCAG CAGTAGCAGT 
AGCAGCAATG GGAACAACAA CATGCTATGC CCGTACGATA AGGAAACGCC CTGTGATCGC 
CTGCAGTTTC CCTGCATCCG TTGCAACTAC AATCATGGAT GCATCTACGG CCGGGACTTG 
AATGTAACCT GCGAGGTGAT CAACAATGTC CAGTGCCTGG GCGAACGGAG TTTCCAGCGA 
CAAATGAATT GCCGATACTG CTACCAAACG GAAATGTGGC AACAGAGCTG TGGCCAGCGC 
TCCAGTTGCA ACTCGGCGAC GGATAAGCTA TTCCGTACCA ACTGCACCGT GCACCATGAT 
GTGCTCTGCC TCGGCAATCG ATCCTTTACC CGCAACCTGC GATGCAACTG GACGCAGGGC 
TATCGGTGGA GCACAGCCCT GCTGATTAGC CTCACGCTAG GGGGCTTTGG AGCCGATCGA 
TTCTACTTGG GCCACTGGCA GGAAGGGATT GGAAAGCTGT TCAGCTTTGG CGGCCTCGGC 
GTCTGGACCA TCATCGATGT CCTGCTCATC TCGATGCATT ATTTGGGGCC AGCGGATGGC 
TCACTTTACA TATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_524644.1
CDS	276..1130
Translation	MRLQRQCIVVNMRSAIVLIMIFVLTGIRNSETASGGNQMDLSDSKGDHKDNSNASNGNGNANDNEVYVPPLVSSMVAKSGGGAGGLLDNITAYSSSSSSSSSNGNNNMLCPYDKETPCDRLQFPCIRCNYNHGCIYGRDLNVTCEVINNVQCLGERSFQRQMNCRYCYQTEMWQQSCGQRSSCNSATDKLFRTNCTVHHDVLCLGNRSFTRNLRCNWTQGYRWSTALLISLTLGGFGADRFYLGHWQEGIGKLFSFGGLGVWTIIDVLLISMHYLGPADGSLYI

Target ORF information:

RefSeq Version	NM_079905.3
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster almondex (amx), transcript variant A, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_079905.3

ORF Insert Sequence:

ATGAGGCTCC AACGACAGTG CATTGTGGTC AACATGCGAT CGGCCATTGT CCTGATCATG 
ATCTTCGTGC TGACGGGGAT CAGGAACAGC GAAACGGCCA GCGGTGGCAA CCAGATGGAC 
TTATCGGACT CAAAAGGCGA TCACAAGGAT AACAGCAATG CGAGCAATGG CAATGGAAAT 
GCCAACGATA ACGAGGTGTA TGTGCCGCCC CTGGTGTCCA GCATGGTGGC CAAGAGTGGA 
GGAGGTGCCG GTGGACTCCT GGACAACATA ACCGCCTACA GCAGCAGCAG CAGTAGCAGT 
AGCAGCAATG GGAACAACAA CATGCTATGC CCGTACGATA AGGAAACGCC CTGTGATCGC 
CTGCAGTTTC CCTGCATCCG TTGCAACTAC AATCATGGAT GCATCTACGG CCGGGACTTG 
AATGTAACCT GCGAGGTGAT CAACAATGTC CAGTGCCTGG GCGAACGGAG TTTCCAGCGA 
CAAATGAATT GCCGATACTG CTACCAAACG GAAATGTGGC AACAGAGCTG TGGCCAGCGC 
TCCAGTTGCA ACTCGGCGAC GGATAAGCTA TTCCGTACCA ACTGCACCGT GCACCATGAT 
GTGCTCTGCC TCGGCAATCG ATCCTTTACC CGCAACCTGC GATGCAACTG GACGCAGGGC 
TATCGGTGGA GCACAGCCCT GCTGATTAGC CTCACGCTAG GGGGCTTTGG AGCCGATCGA 
TTCTACTTGG GCCACTGGCA GGAAGGGATT GGAAAGCTGT TCAGCTTTGG CGGCCTCGGC 
GTCTGGACCA TCATCGATGT CCTGCTCATC TCGATGCATT ATTTGGGGCC AGCGGATGGC 
TCACTTTACA TATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

amx ( NM_001258662.2 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_001245591.1 Drosophila melanogaster almondex (amx), transcript variant B, mRNA.

Price & Availability↑

CloneID	OFa02288
Clone ID Related Accession (Same CDS sequence)	NM_079905.3 , NM_001258662.2
Accession Version	NM_001258662.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 855bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	almondex, isoform B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). On Jul 15, 2014 this sequence version replaced NM_001258662.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGAGGCTCC AACGACAGTG CATTGTGGTC AACATGCGAT CGGCCATTGT CCTGATCATG 
ATCTTCGTGC TGACGGGGAT CAGGAACAGC GAAACGGCCA GCGGTGGCAA CCAGATGGAC 
TTATCGGACT CAAAAGGCGA TCACAAGGAT AACAGCAATG CGAGCAATGG CAATGGAAAT 
GCCAACGATA ACGAGGTGTA TGTGCCGCCC CTGGTGTCCA GCATGGTGGC CAAGAGTGGA 
GGAGGTGCCG GTGGACTCCT GGACAACATA ACCGCCTACA GCAGCAGCAG CAGTAGCAGT 
AGCAGCAATG GGAACAACAA CATGCTATGC CCGTACGATA AGGAAACGCC CTGTGATCGC 
CTGCAGTTTC CCTGCATCCG TTGCAACTAC AATCATGGAT GCATCTACGG CCGGGACTTG 
AATGTAACCT GCGAGGTGAT CAACAATGTC CAGTGCCTGG GCGAACGGAG TTTCCAGCGA 
CAAATGAATT GCCGATACTG CTACCAAACG GAAATGTGGC AACAGAGCTG TGGCCAGCGC 
TCCAGTTGCA ACTCGGCGAC GGATAAGCTA TTCCGTACCA ACTGCACCGT GCACCATGAT 
GTGCTCTGCC TCGGCAATCG ATCCTTTACC CGCAACCTGC GATGCAACTG GACGCAGGGC 
TATCGGTGGA GCACAGCCCT GCTGATTAGC CTCACGCTAG GGGGCTTTGG AGCCGATCGA 
TTCTACTTGG GCCACTGGCA GGAAGGGATT GGAAAGCTGT TCAGCTTTGG CGGCCTCGGC 
GTCTGGACCA TCATCGATGT CCTGCTCATC TCGATGCATT ATTTGGGGCC AGCGGATGGC 
TCACTTTACA TATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001245591.1
CDS	65..919
Translation	MRLQRQCIVVNMRSAIVLIMIFVLTGIRNSETASGGNQMDLSDSKGDHKDNSNASNGNGNANDNEVYVPPLVSSMVAKSGGGAGGLLDNITAYSSSSSSSSSNGNNNMLCPYDKETPCDRLQFPCIRCNYNHGCIYGRDLNVTCEVINNVQCLGERSFQRQMNCRYCYQTEMWQQSCGQRSSCNSATDKLFRTNCTVHHDVLCLGNRSFTRNLRCNWTQGYRWSTALLISLTLGGFGADRFYLGHWQEGIGKLFSFGGLGVWTIIDVLLISMHYLGPADGSLYI

Target ORF information:

RefSeq Version	NM_001258662.2
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster almondex (amx), transcript variant B, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001258662.2

ORF Insert Sequence:

ATGAGGCTCC AACGACAGTG CATTGTGGTC AACATGCGAT CGGCCATTGT CCTGATCATG 
ATCTTCGTGC TGACGGGGAT CAGGAACAGC GAAACGGCCA GCGGTGGCAA CCAGATGGAC 
TTATCGGACT CAAAAGGCGA TCACAAGGAT AACAGCAATG CGAGCAATGG CAATGGAAAT 
GCCAACGATA ACGAGGTGTA TGTGCCGCCC CTGGTGTCCA GCATGGTGGC CAAGAGTGGA 
GGAGGTGCCG GTGGACTCCT GGACAACATA ACCGCCTACA GCAGCAGCAG CAGTAGCAGT 
AGCAGCAATG GGAACAACAA CATGCTATGC CCGTACGATA AGGAAACGCC CTGTGATCGC 
CTGCAGTTTC CCTGCATCCG TTGCAACTAC AATCATGGAT GCATCTACGG CCGGGACTTG 
AATGTAACCT GCGAGGTGAT CAACAATGTC CAGTGCCTGG GCGAACGGAG TTTCCAGCGA 
CAAATGAATT GCCGATACTG CTACCAAACG GAAATGTGGC AACAGAGCTG TGGCCAGCGC 
TCCAGTTGCA ACTCGGCGAC GGATAAGCTA TTCCGTACCA ACTGCACCGT GCACCATGAT 
GTGCTCTGCC TCGGCAATCG ATCCTTTACC CGCAACCTGC GATGCAACTG GACGCAGGGC 
TATCGGTGGA GCACAGCCCT GCTGATTAGC CTCACGCTAG GGGGCTTTGG AGCCGATCGA 
TTCTACTTGG GCCACTGGCA GGAAGGGATT GGAAAGCTGT TCAGCTTTGG CGGCCTCGGC 
GTCTGGACCA TCATCGATGT CCTGCTCATC TCGATGCATT ATTTGGGGCC AGCGGATGGC 
TCACTTTACA TATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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amx cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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