Mtl cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mtl
Entrez Gene ID	43319
Full Name	Mig-2-like
Synonyms	5588,CG5588,Dmel\CG5588,MTL,Mt1/Mig2-like,Rac,Rac GTPase,Rac-like,dMig-2,mtl
General protein information	Preferred Names Mig-2-like Names CG5588 gene product from transcript CG5588-RC CG5588-PA CG5588-PB CG5588-PC Mtl(Rac-like) Mtl-PA Mtl-PB Mtl-PC Rac Rac GTPase mig-2-like
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 3R Map Location: 98A13-98A13

mRNA and Protein(s)

mRNA	Protein	Name
NM_079809.3	NP_524533.1	Mig-2-like, isoform B
NM_170344.2	NP_733223.1	Mig-2-like, isoform C
NM_170343.2	NP_733222.1	Mig-2-like, isoform A

Pathways from BioSystems

Homologies

Arabidopsis thaliana (thale cress)	RAC3	NP_195228.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001573	XP_551238.2
Oryza sativa (rice)	Os02g0834000	NP_001048639.1
Drosophila melanogaster (fruit fly)	Mtl	NP_524533.1
Caenorhabditis elegans (roundworm)	mig-2	NP_509931.1
Arabidopsis thaliana (thale cress)	ARAC5	NP_177712.1
Arabidopsis thaliana (thale cress)	ROP2	NP_173437.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Rac1, Rac2 and Mtl, have overlapping functions in the control of epithelial morphogenesis, myoblast fusion, and axon growth and guidance
Title: Rac function and regulation during Drosophila development.

axon growth, guidance and branching could be controlled by differential activation of Rac signalling pathways
Title: Rac GTPases control axon growth, guidance and branching.

The following Mtl gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mtl cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OFa06343	NM_170343.2 Latest version!	Drosophila melanogaster Mig-2-like (Mtl), transcript variant A, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OFa06343	NM_079809.3 Latest version!	Drosophila melanogaster Mig-2-like (Mtl), transcript variant B, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OFa06343	NM_170344.2 Latest version!	Drosophila melanogaster Mig-2-like (Mtl), transcript variant C, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mtl ( NM_079809.3 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_524533.1 Drosophila melanogaster Mig-2-like (Mtl), transcript variant B, mRNA.

Price & Availability↑

CloneID	OFa06343
Clone ID Related Accession (Same CDS sequence)	NM_079809.3 , NM_170344.2 , NM_170343.2
Accession Version	NM_079809.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 588bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	Mig-2-like, isoform B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033777). On Jan 31, 2011 this sequence version replaced NM_079809.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGTCAACCG GAAGGCCCAT AAAGTGTGTA GTCGTTGGTG ACGGCACCGT CGGAAAGACC 
TGCATGCTAA TCTCCTACAC GACAGACTGC TTTCCCGGCG AATATGTGCC CACAGTCTTC 
GACAACTACT CGGCGCCCAT GCAAGTGGAC ACAATACAGG TCTCGCTGGG ACTGTGGGAT 
ACGGCGGGTC AGGAGGACTA CGACCGCCTG AGACCGCTAT CCTACCCGCA GACAGACGTT 
TTCCTGATAT GCTACAGCGT GGCGAGTCCC TCGTCCTTTG AGAACGTCAC CTCGAAATGG 
TATCCGGAGA TAAAGCACCA CTGTCCCGAT GCGCCCATCA TTCTAGTTGG CACCAAAATC 
GATTTGCGCG AAGATCGAGA GACACTCAGC GGCCTGGCAG AGCAGGGACT GACGCCGCTG 
AAGCGCGAGC AGGGCCAGAA GCTGGCAAAC AAGATACGCG CTGTGAAATA CATGGAGTGC 
TCCGCCTTGA CGCAGCGCGG TCTCAAGCCG GTGTTCGAGG AAGCGGTGCG CGCGGTGCTC 
AGACCAGAGC CGCTAAAGCG ACGCCAGCGA AAGTGTTTAA TAATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_524533.1
CDS	339..926
Translation	MSTGRPIKCVVVGDGTVGKTCMLISYTTDCFPGEYVPTVFDNYSAPMQVDTIQVSLGLWDTAGQEDYDRLRPLSYPQTDVFLICYSVASPSSFENVTSKWYPEIKHHCPDAPIILVGTKIDLREDRETLSGLAEQGLTPLKREQGQKLANKIRAVKYMECSALTQRGLKPVFEEAVRAVLRPEPLKRRQRKCLIM

Target ORF information:

RefSeq Version	NM_079809.3
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster Mig-2-like (Mtl), transcript variant B, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_079809.3

ORF Insert Sequence:

ATGTCAACCG GAAGGCCCAT AAAGTGTGTA GTCGTTGGTG ACGGCACCGT CGGAAAGACC 
TGCATGCTAA TCTCCTACAC GACAGACTGC TTTCCCGGCG AATATGTGCC CACAGTCTTC 
GACAACTACT CGGCGCCCAT GCAAGTGGAC ACAATACAGG TCTCGCTGGG ACTGTGGGAT 
ACGGCGGGTC AGGAGGACTA CGACCGCCTG AGACCGCTAT CCTACCCGCA GACAGACGTT 
TTCCTGATAT GCTACAGCGT GGCGAGTCCC TCGTCCTTTG AGAACGTCAC CTCGAAATGG 
TATCCGGAGA TAAAGCACCA CTGTCCCGAT GCGCCCATCA TTCTAGTTGG CACCAAAATC 
GATTTGCGCG AAGATCGAGA GACACTCAGC GGCCTGGCAG AGCAGGGACT GACGCCGCTG 
AAGCGCGAGC AGGGCCAGAA GCTGGCAAAC AAGATACGCG CTGTGAAATA CATGGAGTGC 
TCCGCCTTGA CGCAGCGCGG TCTCAAGCCG GTGTTCGAGG AAGCGGTGCG CGCGGTGCTC 
AGACCAGAGC CGCTAAAGCG ACGCCAGCGA AAGTGTTTAA TAATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mtl ( NM_170344.2 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_733223.1 Drosophila melanogaster Mig-2-like (Mtl), transcript variant C, mRNA.

Price & Availability↑

CloneID	OFa06343
Clone ID Related Accession (Same CDS sequence)	NM_079809.3 , NM_170344.2 , NM_170343.2
Accession Version	NM_170344.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 588bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	Mig-2-like, isoform C
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033777). On Jan 31, 2011 this sequence version replaced NM_170344.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGTCAACCG GAAGGCCCAT AAAGTGTGTA GTCGTTGGTG ACGGCACCGT CGGAAAGACC 
TGCATGCTAA TCTCCTACAC GACAGACTGC TTTCCCGGCG AATATGTGCC CACAGTCTTC 
GACAACTACT CGGCGCCCAT GCAAGTGGAC ACAATACAGG TCTCGCTGGG ACTGTGGGAT 
ACGGCGGGTC AGGAGGACTA CGACCGCCTG AGACCGCTAT CCTACCCGCA GACAGACGTT 
TTCCTGATAT GCTACAGCGT GGCGAGTCCC TCGTCCTTTG AGAACGTCAC CTCGAAATGG 
TATCCGGAGA TAAAGCACCA CTGTCCCGAT GCGCCCATCA TTCTAGTTGG CACCAAAATC 
GATTTGCGCG AAGATCGAGA GACACTCAGC GGCCTGGCAG AGCAGGGACT GACGCCGCTG 
AAGCGCGAGC AGGGCCAGAA GCTGGCAAAC AAGATACGCG CTGTGAAATA CATGGAGTGC 
TCCGCCTTGA CGCAGCGCGG TCTCAAGCCG GTGTTCGAGG AAGCGGTGCG CGCGGTGCTC 
AGACCAGAGC CGCTAAAGCG ACGCCAGCGA AAGTGTTTAA TAATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_733223.1
CDS	215..802
Translation	MSTGRPIKCVVVGDGTVGKTCMLISYTTDCFPGEYVPTVFDNYSAPMQVDTIQVSLGLWDTAGQEDYDRLRPLSYPQTDVFLICYSVASPSSFENVTSKWYPEIKHHCPDAPIILVGTKIDLREDRETLSGLAEQGLTPLKREQGQKLANKIRAVKYMECSALTQRGLKPVFEEAVRAVLRPEPLKRRQRKCLIM

Target ORF information:

RefSeq Version	NM_170344.2
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster Mig-2-like (Mtl), transcript variant C, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_170344.2

ORF Insert Sequence:

ATGTCAACCG GAAGGCCCAT AAAGTGTGTA GTCGTTGGTG ACGGCACCGT CGGAAAGACC 
TGCATGCTAA TCTCCTACAC GACAGACTGC TTTCCCGGCG AATATGTGCC CACAGTCTTC 
GACAACTACT CGGCGCCCAT GCAAGTGGAC ACAATACAGG TCTCGCTGGG ACTGTGGGAT 
ACGGCGGGTC AGGAGGACTA CGACCGCCTG AGACCGCTAT CCTACCCGCA GACAGACGTT 
TTCCTGATAT GCTACAGCGT GGCGAGTCCC TCGTCCTTTG AGAACGTCAC CTCGAAATGG 
TATCCGGAGA TAAAGCACCA CTGTCCCGAT GCGCCCATCA TTCTAGTTGG CACCAAAATC 
GATTTGCGCG AAGATCGAGA GACACTCAGC GGCCTGGCAG AGCAGGGACT GACGCCGCTG 
AAGCGCGAGC AGGGCCAGAA GCTGGCAAAC AAGATACGCG CTGTGAAATA CATGGAGTGC 
TCCGCCTTGA CGCAGCGCGG TCTCAAGCCG GTGTTCGAGG AAGCGGTGCG CGCGGTGCTC 
AGACCAGAGC CGCTAAAGCG ACGCCAGCGA AAGTGTTTAA TAATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mtl ( NM_170343.2 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_733222.1 Drosophila melanogaster Mig-2-like (Mtl), transcript variant A, mRNA.

Price & Availability↑

CloneID	OFa06343
Clone ID Related Accession (Same CDS sequence)	NM_079809.3 , NM_170344.2 , NM_170343.2
Accession Version	NM_170343.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 588bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	Mig-2-like, isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033777). On Jan 31, 2011 this sequence version replaced NM_170343.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGTCAACCG GAAGGCCCAT AAAGTGTGTA GTCGTTGGTG ACGGCACCGT CGGAAAGACC 
TGCATGCTAA TCTCCTACAC GACAGACTGC TTTCCCGGCG AATATGTGCC CACAGTCTTC 
GACAACTACT CGGCGCCCAT GCAAGTGGAC ACAATACAGG TCTCGCTGGG ACTGTGGGAT 
ACGGCGGGTC AGGAGGACTA CGACCGCCTG AGACCGCTAT CCTACCCGCA GACAGACGTT 
TTCCTGATAT GCTACAGCGT GGCGAGTCCC TCGTCCTTTG AGAACGTCAC CTCGAAATGG 
TATCCGGAGA TAAAGCACCA CTGTCCCGAT GCGCCCATCA TTCTAGTTGG CACCAAAATC 
GATTTGCGCG AAGATCGAGA GACACTCAGC GGCCTGGCAG AGCAGGGACT GACGCCGCTG 
AAGCGCGAGC AGGGCCAGAA GCTGGCAAAC AAGATACGCG CTGTGAAATA CATGGAGTGC 
TCCGCCTTGA CGCAGCGCGG TCTCAAGCCG GTGTTCGAGG AAGCGGTGCG CGCGGTGCTC 
AGACCAGAGC CGCTAAAGCG ACGCCAGCGA AAGTGTTTAA TAATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_733222.1
CDS	244..831
Translation	MSTGRPIKCVVVGDGTVGKTCMLISYTTDCFPGEYVPTVFDNYSAPMQVDTIQVSLGLWDTAGQEDYDRLRPLSYPQTDVFLICYSVASPSSFENVTSKWYPEIKHHCPDAPIILVGTKIDLREDRETLSGLAEQGLTPLKREQGQKLANKIRAVKYMECSALTQRGLKPVFEEAVRAVLRPEPLKRRQRKCLIM

Target ORF information:

RefSeq Version	NM_170343.2
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster Mig-2-like (Mtl), transcript variant A, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_170343.2

ORF Insert Sequence:

ATGTCAACCG GAAGGCCCAT AAAGTGTGTA GTCGTTGGTG ACGGCACCGT CGGAAAGACC 
TGCATGCTAA TCTCCTACAC GACAGACTGC TTTCCCGGCG AATATGTGCC CACAGTCTTC 
GACAACTACT CGGCGCCCAT GCAAGTGGAC ACAATACAGG TCTCGCTGGG ACTGTGGGAT 
ACGGCGGGTC AGGAGGACTA CGACCGCCTG AGACCGCTAT CCTACCCGCA GACAGACGTT 
TTCCTGATAT GCTACAGCGT GGCGAGTCCC TCGTCCTTTG AGAACGTCAC CTCGAAATGG 
TATCCGGAGA TAAAGCACCA CTGTCCCGAT GCGCCCATCA TTCTAGTTGG CACCAAAATC 
GATTTGCGCG AAGATCGAGA GACACTCAGC GGCCTGGCAG AGCAGGGACT GACGCCGCTG 
AAGCGCGAGC AGGGCCAGAA GCTGGCAAAC AAGATACGCG CTGTGAAATA CATGGAGTGC 
TCCGCCTTGA CGCAGCGCGG TCTCAAGCCG GTGTTCGAGG AAGCGGTGCG CGCGGTGCTC 
AGACCAGAGC CGCTAAAGCG ACGCCAGCGA AAGTGTTTAA TAATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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Mtl cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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