veli cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	veli
Entrez Gene ID	43003
Full Name	CG7662 gene product from transcript CG7662-RA
Synonyms	CG7662,D-veli,DLin-7,DLin7,Dmel\CG7662,Dveli,Flin-7,Lin-7,Veli,d-Veli,dLin-7,dLin7,dVeli,lin-7,lin7
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 3R Map Location: 96B19-96B19

mRNA and Protein(s)

mRNA	Protein	Name
NM_143073.4	NP_651330.1	veli, isoform A
NM_170197.3	NP_733076.2	veli, isoform C

Pathways from BioSystems

Homologies

	LIN7B	XP_001114658.1
Bos taurus (cattle)	LIN7B	NP_001040042.1
Drosophila melanogaster (fruit fly)	veli	NP_651330.1
Homo sapiens (human)	LIN7B	NP_071448.1
Mus musculus (house mouse)	Lin7b	NP_035828.1
Danio rerio (zebrafish)	lin7b	NP_001018569.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP005858	XP_315884.3
Xenopus tropicalis (tropical clawed frog)	lin7b	XP_002934676.1
Canis lupus familiaris (dog)	LIN7B	XP_851922.2
Rattus norvegicus (Norway rat)	Lin7b	NP_068526.1
Caenorhabditis elegans (roundworm)	lin-7	NP_001122664.2

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

At the photoreceptor synapse, DLin-7 acts as part of a conserved DLin-7/CASK/DlgS97 complex required to control the number of capitate projections and active zones, important specializations in the that are essential for proper neurotransmission.
Title: DLin-7 is required in postsynaptic lamina neurons to prevent light-induced photoreceptor degeneration in Drosophila.

DlgS97-Metro-DLin-7-type complexes control the proper organization of a synaptic junction; findings accentuate the importance of perisynaptic scaffold complexes for synaptic stabilization and organization
Title: A perisynaptic m?nage ? trois between Dlg, DLin-7, and Metro controls proper organization of Drosophila synaptic junctions.

study reports that Lin-7, a scaffolding protein with one Lin-2/Lin-7 domain & one PSD-95/Dlg/ZO-1 domain, is associated with the Crumbs complex in subapical region of embryonic & follicle epithelia & at the stalk membrane of adult photoreceptor cells
Title: Drosophila Lin-7 is a component of the Crumbs complex in epithelia and photoreceptor cells and prevents light-induced retinal degeneration.

recruitment of DLin-7 to MAGUK-based protein complexes is defined by cell-type specific mechanisms; DLin-7 acts downstream of Sdt in epithelia and downstream of Dlg at synapses [VELI is a synonym for Lin-7]
Title: Cell type-specific recruitment of Drosophila Lin-7 to distinct MAGUK-based protein complexes defines novel roles for Sdt and Dlg-S97.

The following veli gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the veli cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa08798	NM_143073.4 Latest version!	Drosophila melanogaster veli, transcript variant A (veli), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OFa08799	NM_170197.3 Latest version!	Drosophila melanogaster veli, transcript variant C (veli), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

veli ( NM_143073.4 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_651330.1 Drosophila melanogaster veli, transcript variant A (veli), mRNA.

Price & Availability↑

CloneID	OFa08798
Clone ID Related Accession (Same CDS sequence)	NM_143073.4
Accession Version	NM_143073.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 588bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	veli, isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033777). On Jan 16, 2013 this sequence version replaced NM_143073.3. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGCCGATA ACGCAGAACC ACTGACTTTG TCCAGAGATG TCAAAAGATC GATAGAGCTC 
TTGGAAAAGC TGCAAGCGAG TGGCGACTTC CCCACGACAA AACTGGCCGC CCTGCAGAAG 
GTGCTCAACT CGGACTTCAT GACCTCCGTG CGGGAGGTGT ACGAGCACGT CTACGAGACG 
GTGGACATCC AGGGCTCCCA CGACGTGAGG GCATCCGCCA CTGCCAAGGC CACTGTGGCA 
GCCTTCGCAG CCAGCGAGGG GCACGCTCAT CCCAGAGTCG TCGAGCTCCC GAAAACGGAG 
GAGGGCTTGG GTTTCAATGT AATGGGGGGC AAGGAGCAAA ACTCGCCCAT CTATATATCC 
CGAATAATAC CTGGAGGCGT GGCTGACAGG CATGGTGGTC TGAAAAGGGG AGATCAACTT 
TTGTCTGTGA ATGGTGTGTC TGTCGAAGGA GAAAACCACG AGAAGGCCGT AGAGCTATTA 
AAGCAAGCTG TCGGATCTGT AAAGCTGGTG GTACGCTACA CACCAAAGGT TCTCGAGGAA 
ATGGAAATGC GATTTGATAA GCAACGCAAC ACACGTCGTC GCCAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_651330.1
CDS	78..665
Translation	MADNAEPLTLSRDVKRSIELLEKLQASGDFPTTKLAALQKVLNSDFMTSVREVYEHVYETVDIQGSHDVRASATAKATVAAFAASEGHAHPRVVELPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVNGVSVEGENHEKAVELLKQAVGSVKLVVRYTPKVLEEMEMRFDKQRNTRRRQ

Target ORF information:

RefSeq Version	NM_143073.4
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster veli, transcript variant A (veli), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_143073.4

ORF Insert Sequence:

ATGGCCGATA ACGCAGAACC ACTGACTTTG TCCAGAGATG TCAAAAGATC GATAGAGCTC 
TTGGAAAAGC TGCAAGCGAG TGGCGACTTC CCCACGACAA AACTGGCCGC CCTGCAGAAG 
GTGCTCAACT CGGACTTCAT GACCTCCGTG CGGGAGGTGT ACGAGCACGT CTACGAGACG 
GTGGACATCC AGGGCTCCCA CGACGTGAGG GCATCCGCCA CTGCCAAGGC CACTGTGGCA 
GCCTTCGCAG CCAGCGAGGG GCACGCTCAT CCCAGAGTCG TCGAGCTCCC GAAAACGGAG 
GAGGGCTTGG GTTTCAATGT AATGGGGGGC AAGGAGCAAA ACTCGCCCAT CTATATATCC 
CGAATAATAC CTGGAGGCGT GGCTGACAGG CATGGTGGTC TGAAAAGGGG AGATCAACTT 
TTGTCTGTGA ATGGTGTGTC TGTCGAAGGA GAAAACCACG AGAAGGCCGT AGAGCTATTA 
AAGCAAGCTG TCGGATCTGT AAAGCTGGTG GTACGCTACA CACCAAAGGT TCTCGAGGAA 
ATGGAAATGC GATTTGATAA GCAACGCAAC ACACGTCGTC GCCAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

veli ( NM_170197.3 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_733076.2 Drosophila melanogaster veli, transcript variant C (veli), mRNA.

Price & Availability↑

CloneID	OFa08799
Clone ID Related Accession (Same CDS sequence)	NM_170197.3
Accession Version	NM_170197.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 741bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	veli, isoform C
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033777). On Jan 16, 2013 this sequence version replaced NM_170197.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGCCGATA ACGCAGAACC ACTGACTTTG TCCAGAGATG TCAAAAGATC GATAGAGCTC 
TTGGAAAAGC TGCAAGCGAG TGGCGACTTC CCCACGACAA AACTGGCCGC CCTGCAGAAG 
GTGCTCAACT CGGACTTCAT GACCTCCGTG CGGGAGGTGT ACGAGCACGT CTACGAGACG 
GTGGACATCC AGGGCTCCCA CGACGTGAGG GCATCCGCCA CTGCCAAGGC CACTGTGGCA 
GCCTTCGCAG CCAGCGAGGG GCACGCTCAT CCCAGAGTCG TCGAGCTCCC GAAAACGGAG 
GAGGGTAAGA CACGCCCCTA TGAGCTAAGA ATCGAGGGGA TTCCCCTATA TCATAAAACC 
AATACCTTGA TTGTAAAGGT CTATAGACCG AGAATATATG TTTCTATTAT ACATCTTATA 
TGGAAAGCTT TATCAATCTT TAATTTTTGT TTTTCAGGCT TGGGTTTCAA TGTAATGGGG 
GGCAAGGAGC AAAACTCGCC CATCTATATA TCCCGAATAA TACCTGGAGG CGTGGCTGAC 
AGGCATGGTG GTCTGAAAAG GGGAGATCAA CTTTTGTCTG TGAATGGTGT GTCTGTCGAA 
GGAGAAAACC ACGAGAAGGC CGTAGAGCTA TTAAAGCAAG CTGTCGGATC TGTAAAGCTG 
GTGGTACGCT ACACACCAAA GGTTCTCGAG GAAATGGAAA TGCGATTTGA TAAGCAACGC 
AACACACGTC GTCGCCAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_733076.2
CDS	78..818
Translation	MADNAEPLTLSRDVKRSIELLEKLQASGDFPTTKLAALQKVLNSDFMTSVREVYEHVYETVDIQGSHDVRASATAKATVAAFAASEGHAHPRVVELPKTEEGKTRPYELRIEGIPLYHKTNTLIVKVYRPRIYVSIIHLIWKALSIFNFCFSGLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVNGVSVEGENHEKAVELLKQAVGSVKLVVRYTPKVLEEMEMRFDKQRNTRRRQ

Target ORF information:

RefSeq Version	NM_170197.3
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster veli, transcript variant C (veli), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_170197.3

ORF Insert Sequence:

ATGGCCGATA ACGCAGAACC ACTGACTTTG TCCAGAGATG TCAAAAGATC GATAGAGCTC 
TTGGAAAAGC TGCAAGCGAG TGGCGACTTC CCCACGACAA AACTGGCCGC CCTGCAGAAG 
GTGCTCAACT CGGACTTCAT GACCTCCGTG CGGGAGGTGT ACGAGCACGT CTACGAGACG 
GTGGACATCC AGGGCTCCCA CGACGTGAGG GCATCCGCCA CTGCCAAGGC CACTGTGGCA 
GCCTTCGCAG CCAGCGAGGG GCACGCTCAT CCCAGAGTCG TCGAGCTCCC GAAAACGGAG 
GAGGGTAAGA CACGCCCCTA TGAGCTAAGA ATCGAGGGGA TTCCCCTATA TCATAAAACC 
AATACCTTGA TTGTAAAGGT CTATAGACCG AGAATATATG TTTCTATTAT ACATCTTATA 
TGGAAAGCTT TATCAATCTT TAATTTTTGT TTTTCAGGCT TGGGTTTCAA TGTAATGGGG 
GGCAAGGAGC AAAACTCGCC CATCTATATA TCCCGAATAA TACCTGGAGG CGTGGCTGAC 
AGGCATGGTG GTCTGAAAAG GGGAGATCAA CTTTTGTCTG TGAATGGTGT GTCTGTCGAA 
GGAGAAAACC ACGAGAAGGC CGTAGAGCTA TTAAAGCAAG CTGTCGGATC TGTAAAGCTG 
GTGGTACGCT ACACACCAAA GGTTCTCGAG GAAATGGAAA TGCGATTTGA TAAGCAACGC 
AACACACGTC GTCGCCAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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veli cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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