modSP cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	modSP
Entrez Gene ID	42032
Full Name	modular serine protease
Synonyms	CG10100,CG17557,CG31217,CT28389,Dm-SP,Dmel\CG31217,LDL,Ldlr,ModSP,SP172,SP53,Ser89E,W,X
General protein information	Preferred Names modular serine protease Names CG31217 gene product from transcript CG31217-RA CG31217-PA low density lipoprotein receptor-like 'a' repeats modSP-PA predicted gene W predicted gene X serine protease like 89E serine protease-like
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 3R Map Location: 89D6-89D6

mRNA and Protein(s)

mRNA	Protein	Name
NM_080515.3	NP_536776.2	modular serine protease

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001798	XP_321263.5
Drosophila melanogaster (fruit fly)	modSP	NP_536776.2

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results demonstrate the essential role of CG31217 serine protease, named ModSP (for modular serine protease), in the activation of the Toll pathway by gram-positive bacteria and fungi.
Title: A single modular serine protease integrates signals from pattern-recognition receptors upstream of the Drosophila Toll pathway.

The following modSP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the modSP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa05160	NM_080515.3 Latest version!	Drosophila melanogaster modular serine protease (modSP), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

modSP ( NM_080515.3 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_536776.2 Drosophila melanogaster modular serine protease (modSP), mRNA.

Price & Availability↑

CloneID	OFa05160
Clone ID Related Accession (Same CDS sequence)	NM_080515.3
Accession Version	NM_080515.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1887bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	modular serine protease
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033777). On Jan 16, 2013 this sequence version replaced NM_080515.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGCAACTAA TATCGTTTTT ATCAAATCCA TTGTTCTTCT GCGCGCTTTT ATTGAAATTC 
AGAACAATAT TTGCGGCATG TGACAGCTCA CAGTTTGAGT GCGACAACGG CAGCTGCATT 
TCGCAGTACG ATGTCTGCAA TGGCGAGAAG AACTGCCCGG ATGGATCCGA TGAGACGGCG 
TTGACCTGTG TCTCCCAGCG GCAGCACTGC ACCAAGCCCT ATTTCCAGTG CACCTATGGA 
GCATGTGTGA TCGGGACAGC TGGGTGCAAT GGAGTCAATG AGTGCGCAGA TGGTTCCGAT 
GAGACCAGGT TGAGATGCGG CAACGAGGAC GATATACGGC AGCACGACCG ACGGCTTCAA 
GGCAATTGCA AGGAAAATGA GTTCAAATGC CCATCCGGAA TTTGCCTGGA CAAGAGCAAC 
TTTCTGTGCG ACGGCAAGGA CGACTGTGCG GATGGAACGG GCTTTGACGA GTCGGTGGAA 
CTGTGCGGCC ACATGGAGTG TCCAGCGTAC TCCTTCAAGT GCGGAACAGG TGGCTGCATC 
TCGGGGTCAT TGTCATGCAA TGGGGAAAAC GACTGCTATG ACGGATCCGA TGAGGCACCA 
CTGCTATGCA ACACCACCAA AAAGGTGACC ACACCCGTGG TGACTGAGAC TCCGCTGGAG 
CTGCTCGGAT GCCCCTTGCC ACTTGGCGAC GAAAGGCCCA TCCTGACGGG TGACGGCAGC 
CGCGTCCTCA CTGGACCCAT CACCCGGGGA ACAGTGCGAT TCTCCTGCAA GCAGGGATAT 
GTGCTGGAGG GAGAGGAGAG CAGCTACTGC GCCAAGAACA AGTGGAGTAC TTCCACAATC 
CCGAAATGCG TGAAATACTG CAGCACTGCC GGAGAATTCG ATGGCTACTC CACGAAGGCC 
TTGTGCACCC ACAATGGACA GCAAGTGGAA TGCCGCAAAC CATTCCATCC GCCCGGCACC 
GAAGTGAAGT TTGTCTGCTC CACCGGATTC AAGACCCTGA GCCCACTGCC AGAAATGCGG 
TGCATGAAGG GAGGATACTG GAACCGCGGA CGCCAGCGAT GCGAGCAGGA CTGCGGCCAG 
CTAGCCACGC CCATAAAACA GTTCTCGTCC GGCGGCTATA CGATCAACAA CACGGTTGTG 
CCCTGGCATG TGGGACTATA TGTGTGGCAC AACGAGAAGG ACTACCACTT TCAGTGCGGA 
GGATCGCTAC TCACCCCGGA CCTAGTCATA ACCGCCGCAC ATTGCGTATA CGACGAGGGT 
ACTCGACTGC CCTACAGCTA CGACACCTTC CGGGTGATTG CGGCCAAGTT CTATCGCAAT 
TACGGAGAAA CTACTCCGGA AGAAAAGCGA CGGGATGTGA GGCTCATAGA AATAGCACCT 
GGCTACAAAG GAAGGACGGA AAACTATTAC CAGGATCTGG CCCTTCTGAC CCTCGACGAG 
CCCTTCGAGC TGAGCCACGT AATCCGGCCC ATTTGCGTTA CCTTCGCCAG CTTTGCAGAG 
AAGGAGAGCG TCACGGATGA TGTGCAGGGC AAGTTCGCTG GCTGGAACAT CGAGAACAAG 
CACGAACTCC AGTTTGTGCC GGCCGTGTCC AAGTCGAATT CCGTGTGCCG TCGGAATCTG 
CGGGACATCC AGGCGGACAA GTTCTGCATC TTCACGCAGG GCAAGTCGCT CGCCTGCCAG 
GGTGACAGTG GCGGTGGATT CACCTCCGAG CTGCCGACCA ACGCCTTCTC CACCTGGAAC 
ACCGCCCGTC ACTTCCTCTT CGGGGTGATC AGCAATGCAC CCAATGCAGA TCAGTGTGCC 
CACAGCCTGA CCGTGATGAC CAACATCCAG CACTTCGAGG ATATGATCCT GAATGCGATG 
AACAGGAGCG TGGAAACTAG GTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_536776.2
CDS	157..2043
Translation	MQLISFLSNPLFFCALLLKFRTIFAACDSSQFECDNGSCISQYDVCNGEKNCPDGSDETALTCVSQRQHCTKPYFQCTYGACVIGTAGCNGVNECADGSDETRLRCGNEDDIRQHDRRLQGNCKENEFKCPSGICLDKSNFLCDGKDDCADGTGFDESVELCGHMECPAYSFKCGTGGCISGSLSCNGENDCYDGSDEAPLLCNTTKKVTTPVVTETPLELLGCPLPLGDERPILTGDGSRVLTGPITRGTVRFSCKQGYVLEGEESSYCAKNKWSTSTIPKCVKYCSTAGEFDGYSTKALCTHNGQQVECRKPFHPPGTEVKFVCSTGFKTLSPLPEMRCMKGGYWNRGRQRCEQDCGQLATPIKQFSSGGYTINNTVVPWHVGLYVWHNEKDYHFQCGGSLLTPDLVITAAHCVYDEGTRLPYSYDTFRVIAAKFYRNYGETTPEEKRRDVRLIEIAPGYKGRTENYYQDLALLTLDEPFELSHVIRPICVTFASFAEKESVTDDVQGKFAGWNIENKHELQFVPAVSKSNSVCRRNLRDIQADKFCIFTQGKSLACQGDSGGGFTSELPTNAFSTWNTARHFLFGVISNAPNADQCAHSLTVMTNIQHFEDMILNAMNRSVETRS

Target ORF information:

RefSeq Version	NM_080515.3
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster modular serine protease (modSP), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_080515.3

ORF Insert Sequence:

ATGCAACTAA TATCGTTTTT ATCAAATCCA TTGTTCTTCT GCGCGCTTTT ATTGAAATTC 
AGAACAATAT TTGCGGCATG TGACAGCTCA CAGTTTGAGT GCGACAACGG CAGCTGCATT 
TCGCAGTACG ATGTCTGCAA TGGCGAGAAG AACTGCCCGG ATGGATCCGA TGAGACGGCG 
TTGACCTGTG TCTCCCAGCG GCAGCACTGC ACCAAGCCCT ATTTCCAGTG CACCTATGGA 
GCATGTGTGA TCGGGACAGC TGGGTGCAAT GGAGTCAATG AGTGCGCAGA TGGTTCCGAT 
GAGACCAGGT TGAGATGCGG CAACGAGGAC GATATACGGC AGCACGACCG ACGGCTTCAA 
GGCAATTGCA AGGAAAATGA GTTCAAATGC CCATCCGGAA TTTGCCTGGA CAAGAGCAAC 
TTTCTGTGCG ACGGCAAGGA CGACTGTGCG GATGGAACGG GCTTTGACGA GTCGGTGGAA 
CTGTGCGGCC ACATGGAGTG TCCAGCGTAC TCCTTCAAGT GCGGAACAGG TGGCTGCATC 
TCGGGGTCAT TGTCATGCAA TGGGGAAAAC GACTGCTATG ACGGATCCGA TGAGGCACCA 
CTGCTATGCA ACACCACCAA AAAGGTGACC ACACCCGTGG TGACTGAGAC TCCGCTGGAG 
CTGCTCGGAT GCCCCTTGCC ACTTGGCGAC GAAAGGCCCA TCCTGACGGG TGACGGCAGC 
CGCGTCCTCA CTGGACCCAT CACCCGGGGA ACAGTGCGAT TCTCCTGCAA GCAGGGATAT 
GTGCTGGAGG GAGAGGAGAG CAGCTACTGC GCCAAGAACA AGTGGAGTAC TTCCACAATC 
CCGAAATGCG TGAAATACTG CAGCACTGCC GGAGAATTCG ATGGCTACTC CACGAAGGCC 
TTGTGCACCC ACAATGGACA GCAAGTGGAA TGCCGCAAAC CATTCCATCC GCCCGGCACC 
GAAGTGAAGT TTGTCTGCTC CACCGGATTC AAGACCCTGA GCCCACTGCC AGAAATGCGG 
TGCATGAAGG GAGGATACTG GAACCGCGGA CGCCAGCGAT GCGAGCAGGA CTGCGGCCAG 
CTAGCCACGC CCATAAAACA GTTCTCGTCC GGCGGCTATA CGATCAACAA CACGGTTGTG 
CCCTGGCATG TGGGACTATA TGTGTGGCAC AACGAGAAGG ACTACCACTT TCAGTGCGGA 
GGATCGCTAC TCACCCCGGA CCTAGTCATA ACCGCCGCAC ATTGCGTATA CGACGAGGGT 
ACTCGACTGC CCTACAGCTA CGACACCTTC CGGGTGATTG CGGCCAAGTT CTATCGCAAT 
TACGGAGAAA CTACTCCGGA AGAAAAGCGA CGGGATGTGA GGCTCATAGA AATAGCACCT 
GGCTACAAAG GAAGGACGGA AAACTATTAC CAGGATCTGG CCCTTCTGAC CCTCGACGAG 
CCCTTCGAGC TGAGCCACGT AATCCGGCCC ATTTGCGTTA CCTTCGCCAG CTTTGCAGAG 
AAGGAGAGCG TCACGGATGA TGTGCAGGGC AAGTTCGCTG GCTGGAACAT CGAGAACAAG 
CACGAACTCC AGTTTGTGCC GGCCGTGTCC AAGTCGAATT CCGTGTGCCG TCGGAATCTG 
CGGGACATCC AGGCGGACAA GTTCTGCATC TTCACGCAGG GCAAGTCGCT CGCCTGCCAG 
GGTGACAGTG GCGGTGGATT CACCTCCGAG CTGCCGACCA ACGCCTTCTC CACCTGGAAC 
ACCGCCCGTC ACTTCCTCTT CGGGGTGATC AGCAATGCAC CCAATGCAGA TCAGTGTGCC 
CACAGCCTGA CCGTGATGAC CAACATCCAG CACTTCGAGG ATATGATCCT GAATGCGATG 
AACAGGAGCG TGGAAACTAG GTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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modSP cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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