Bin1 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	Bin1
Entrez Gene ID	41965
Full Name	Bicoid interacting protein 1
Synonyms	150001_at,BcDNA:RE02417,Bin 1,CG6046,Dmel\CG6046,SAP18,bin1,bin1/dSAP18,dSAP18,dSap18,dsap18,sap18
General protein information	Preferred Names Bicoid interacting protein 1 Names CG6046 gene product from transcript CG6046-RC Bin1-PA Bin1-PB Bin1-PC CG6046-PA CG6046-PB CG6046-PC SIN3-associated polypeptide 18 Sin3A-associated polypeptide p18 bicoid interacting protein 1
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 3R Map Location: 89B7-89B7

mRNA and Protein(s)

mRNA	Protein	Name
NM_079653.3	NP_524377.1	bicoid interacting protein 1, isoform A
NM_001316511.1	NP_001303440.1	bicoid interacting protein 1, isoform B
NM_001316512.1	NP_001303441.1	bicoid interacting protein 1, isoform C

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Gm10094	NP_001135913.1
Arabidopsis thaliana (thale cress)	SAP18	NP_566050.1
Rattus norvegicus (Norway rat)	Sap18	NP_001028857.2
Gallus gallus (chicken)	SAP18	NP_989643.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003036	XP_311841.2
Homo sapiens (human)	SAP18	NP_005861.2
Pan troglodytes (chimpanzee)	SAP18	XP_509567.3
Mus musculus (house mouse)	Sap18	NP_033145.2
Drosophila melanogaster (fruit fly)	Bin1	NP_524377.1
Oryza sativa (rice)	Os02g0122000	NP_001045723.1
Canis lupus familiaris (dog)	SAP18	NP_001239090.1
Rattus norvegicus (Norway rat)	RGD1561590	XP_002727857.1
Danio rerio (zebrafish)	sap18	NP_957014.1
Xenopus tropicalis (tropical clawed frog)	sap18	NP_001016166.1
	SAP18	XP_001085342.2
Bos taurus (cattle)	SAP18	NP_001030544.2
Caenorhabditis elegans (roundworm)	CELE_C16C10.4	NP_497833.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

dSAP18 is a key player in transcriptional responses to stress.
Title: Drosophila melanogaster SAP18 protein is required for environmental stress responses.

Kruppel tethers the SAP18 bound histone deacetylase complex 1 at distinct enhancer elements, which causes repression via histone H3 deacetylation
Title: SAP18 promotes Kr?ppel-dependent transcriptional repression by enhancer-specific histone deacetylation.

Drosophila dSAP18 protein is a nuclear protein that associates with chromosomes and the nuclear matrix and interacts with pinin involved in RNA splicing.
Title: Drosophila dSAP18 is a nuclear protein that associates with chromosomes and the nuclear matrix, and interacts with pinin, a protein factor involved in RNA splicing.

removal of maternal sap18 results in embryos that are missing labrally derived parts of the cephalopharyngeal skeleton
Title: Sap18 is required for the maternal gene bicoid to direct anterior patterning in Drosophila melanogaster.

The following Bin1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Bin1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OFa05099	NM_079653.3 Latest version!	Drosophila melanogaster bicoid interacting protein 1, transcript variant A (Bin1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OFa05099	NM_001316511.1 Latest version!	Drosophila melanogaster bicoid interacting protein 1, transcript variant B (Bin1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OFa05099	NM_001316512.1 Latest version!	Drosophila melanogaster bicoid interacting protein 1, transcript variant C (Bin1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Bin1 ( NM_079653.3 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_524377.1 Drosophila melanogaster bicoid interacting protein 1, transcript variant A (Bin1), mRNA.

Price & Availability↑

CloneID	OFa05099
Clone ID Related Accession (Same CDS sequence)	NM_079653.3 , NM_001316511.1 , NM_001316512.1
Accession Version	NM_079653.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 453bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	bicoid interacting protein 1, isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033777). On Jul 15, 2014 this sequence version replaced NM_079653.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGCCAACG TGGAATCTAT GATTGTGGAG GAAAAGACGC AGGTCAAGCA GATTGACCGC 
GAGAAGACCT GTCCTATGCT GCTCCGTGTC TTCTGCTCTA CGGGACGACA CCACTCCGTG 
TCGGAGTATA TGTTCGGCAA CGTGCCCACC AACGAGCTTC AGATTTACAC CTGGCAAGAC 
GCCACCCTGC ACGAACTGAC CTCTCTGGTG CGAGACGTCA ATCCGGACAC CCGGAAGAAG 
GGCACCTACT TTGACTTTGC TGTCGTGTAC CCCAACTTCC GGAGTAATCA CTTCCAGATG 
CGCGAAATCG GAGTGACCTG CACGGGTCAA AAAGGAATCG ATGATAATAA GACACTTGCT 
CAGGCCAAAT TCAGCATTGG AGACTTTCTG GACATCTCGA TTACTCCGCC CAACCGACTG 
CCGCCAACCG CCAGGCGCCA GCGTCCGTAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_524377.1
CDS	121..573
Translation	MANVESMIVEEKTQVKQIDREKTCPMLLRVFCSTGRHHSVSEYMFGNVPTNELQIYTWQDATLHELTSLVRDVNPDTRKKGTYFDFAVVYPNFRSNHFQMREIGVTCTGQKGIDDNKTLAQAKFSIGDFLDISITPPNRLPPTARRQRPY

Target ORF information:

RefSeq Version	NM_079653.3
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster bicoid interacting protein 1, transcript variant A (Bin1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_079653.3

ORF Insert Sequence:

ATGGCCAACG TGGAATCTAT GATTGTGGAG GAAAAGACGC AGGTCAAGCA GATTGACCGC 
GAGAAGACCT GTCCTATGCT GCTCCGTGTC TTCTGCTCTA CGGGACGACA CCACTCCGTG 
TCGGAGTATA TGTTCGGCAA CGTGCCCACC AACGAGCTTC AGATTTACAC CTGGCAAGAC 
GCCACCCTGC ACGAACTGAC CTCTCTGGTG CGAGACGTCA ATCCGGACAC CCGGAAGAAG 
GGCACCTACT TTGACTTTGC TGTCGTGTAC CCCAACTTCC GGAGTAATCA CTTCCAGATG 
CGCGAAATCG GAGTGACCTG CACGGGTCAA AAAGGAATCG ATGATAATAA GACACTTGCT 
CAGGCCAAAT TCAGCATTGG AGACTTTCTG GACATCTCGA TTACTCCGCC CAACCGACTG 
CCGCCAACCG CCAGGCGCCA GCGTCCGTAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Bin1 ( NM_001316511.1 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_001303440.1 Drosophila melanogaster bicoid interacting protein 1, transcript variant B (Bin1), mRNA.

Price & Availability↑

CloneID	OFa05099
Clone ID Related Accession (Same CDS sequence)	NM_079653.3 , NM_001316511.1 , NM_001316512.1
Accession Version	NM_001316511.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 453bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	bicoid interacting protein 1, isoform B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033777). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGCCAACG TGGAATCTAT GATTGTGGAG GAAAAGACGC AGGTCAAGCA GATTGACCGC 
GAGAAGACCT GTCCTATGCT GCTCCGTGTC TTCTGCTCTA CGGGACGACA CCACTCCGTG 
TCGGAGTATA TGTTCGGCAA CGTGCCCACC AACGAGCTTC AGATTTACAC CTGGCAAGAC 
GCCACCCTGC ACGAACTGAC CTCTCTGGTG CGAGACGTCA ATCCGGACAC CCGGAAGAAG 
GGCACCTACT TTGACTTTGC TGTCGTGTAC CCCAACTTCC GGAGTAATCA CTTCCAGATG 
CGCGAAATCG GAGTGACCTG CACGGGTCAA AAAGGAATCG ATGATAATAA GACACTTGCT 
CAGGCCAAAT TCAGCATTGG AGACTTTCTG GACATCTCGA TTACTCCGCC CAACCGACTG 
CCGCCAACCG CCAGGCGCCA GCGTCCGTAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001303440.1
CDS	2788..3240
Translation	MANVESMIVEEKTQVKQIDREKTCPMLLRVFCSTGRHHSVSEYMFGNVPTNELQIYTWQDATLHELTSLVRDVNPDTRKKGTYFDFAVVYPNFRSNHFQMREIGVTCTGQKGIDDNKTLAQAKFSIGDFLDISITPPNRLPPTARRQRPY

Target ORF information:

RefSeq Version	NM_001316511.1
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster bicoid interacting protein 1, transcript variant B (Bin1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001316511.1

ORF Insert Sequence:

ATGGCCAACG TGGAATCTAT GATTGTGGAG GAAAAGACGC AGGTCAAGCA GATTGACCGC 
GAGAAGACCT GTCCTATGCT GCTCCGTGTC TTCTGCTCTA CGGGACGACA CCACTCCGTG 
TCGGAGTATA TGTTCGGCAA CGTGCCCACC AACGAGCTTC AGATTTACAC CTGGCAAGAC 
GCCACCCTGC ACGAACTGAC CTCTCTGGTG CGAGACGTCA ATCCGGACAC CCGGAAGAAG 
GGCACCTACT TTGACTTTGC TGTCGTGTAC CCCAACTTCC GGAGTAATCA CTTCCAGATG 
CGCGAAATCG GAGTGACCTG CACGGGTCAA AAAGGAATCG ATGATAATAA GACACTTGCT 
CAGGCCAAAT TCAGCATTGG AGACTTTCTG GACATCTCGA TTACTCCGCC CAACCGACTG 
CCGCCAACCG CCAGGCGCCA GCGTCCGTAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Bin1 ( NM_001316512.1 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_001303441.1 Drosophila melanogaster bicoid interacting protein 1, transcript variant C (Bin1), mRNA.

Price & Availability↑

CloneID	OFa05099
Clone ID Related Accession (Same CDS sequence)	NM_079653.3 , NM_001316511.1 , NM_001316512.1
Accession Version	NM_001316512.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 453bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	bicoid interacting protein 1, isoform C
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033777). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGCCAACG TGGAATCTAT GATTGTGGAG GAAAAGACGC AGGTCAAGCA GATTGACCGC 
GAGAAGACCT GTCCTATGCT GCTCCGTGTC TTCTGCTCTA CGGGACGACA CCACTCCGTG 
TCGGAGTATA TGTTCGGCAA CGTGCCCACC AACGAGCTTC AGATTTACAC CTGGCAAGAC 
GCCACCCTGC ACGAACTGAC CTCTCTGGTG CGAGACGTCA ATCCGGACAC CCGGAAGAAG 
GGCACCTACT TTGACTTTGC TGTCGTGTAC CCCAACTTCC GGAGTAATCA CTTCCAGATG 
CGCGAAATCG GAGTGACCTG CACGGGTCAA AAAGGAATCG ATGATAATAA GACACTTGCT 
CAGGCCAAAT TCAGCATTGG AGACTTTCTG GACATCTCGA TTACTCCGCC CAACCGACTG 
CCGCCAACCG CCAGGCGCCA GCGTCCGTAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001303441.1
CDS	692..1144
Translation	MANVESMIVEEKTQVKQIDREKTCPMLLRVFCSTGRHHSVSEYMFGNVPTNELQIYTWQDATLHELTSLVRDVNPDTRKKGTYFDFAVVYPNFRSNHFQMREIGVTCTGQKGIDDNKTLAQAKFSIGDFLDISITPPNRLPPTARRQRPY

Target ORF information:

RefSeq Version	NM_001316512.1
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster bicoid interacting protein 1, transcript variant C (Bin1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001316512.1

ORF Insert Sequence:

ATGGCCAACG TGGAATCTAT GATTGTGGAG GAAAAGACGC AGGTCAAGCA GATTGACCGC 
GAGAAGACCT GTCCTATGCT GCTCCGTGTC TTCTGCTCTA CGGGACGACA CCACTCCGTG 
TCGGAGTATA TGTTCGGCAA CGTGCCCACC AACGAGCTTC AGATTTACAC CTGGCAAGAC 
GCCACCCTGC ACGAACTGAC CTCTCTGGTG CGAGACGTCA ATCCGGACAC CCGGAAGAAG 
GGCACCTACT TTGACTTTGC TGTCGTGTAC CCCAACTTCC GGAGTAATCA CTTCCAGATG 
CGCGAAATCG GAGTGACCTG CACGGGTCAA AAAGGAATCG ATGATAATAA GACACTTGCT 
CAGGCCAAAT TCAGCATTGG AGACTTTCTG GACATCTCGA TTACTCCGCC CAACCGACTG 
CCGCCAACCG CCAGGCGCCA GCGTCCGTAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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Bin1 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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