Psn cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	Psn
Entrez Gene ID	40260
Full Name	Presenilin
Synonyms	CG18803,CG5868,DPS,DPsn,DmPS,Dmel\CG18803,Dps,DrosPS,PS,PS1,PSN,dPsn,l(3)77CDb,pres,psn
General protein information	Preferred Names Presenilin Names CG18803 gene product from transcript CG18803-RA CG18803-PA CG18803-PB CG18803-PC CG18803-PD CG18803-PE Psn-PA Psn-PB Psn-PC Psn-PD Psn-PE dPresenilin pre-senelin presenilin
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 3L Map Location: 77C3-77C3

mRNA and Protein(s)

mRNA	Protein	Name
NM_001144516.2	NP_001137988.1	presenilin, isoform C
NM_079460.2	NP_524184.1	presenilin, isoform A
NM_001275181.1	NP_001262110.1	presenilin, isoform D
NM_001275182.1	NP_001262111.1	presenilin, isoform E
NM_168856.3	NP_730535.1	presenilin, isoform B

Pathways from BioSystems

Homologies

Homo sapiens (human)	PSEN2	NP_000438.2
	PSEN2	XP_002801954.1
Canis lupus familiaris (dog)	PSEN2	XP_005622685.1
Danio rerio (zebrafish)	psen2	NP_571589.2
Xenopus tropicalis (tropical clawed frog)	psen2	NP_001017181.1
Bos taurus (cattle)	PSEN2	NP_776865.2
Rattus norvegicus (Norway rat)	Psen2	NP_112349.2
Drosophila melanogaster (fruit fly)	Psn	NP_001137988.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002957	XP_311942.4
Gallus gallus (chicken)	PSEN2	NP_989633.1
Oryza sativa (rice)	Os01g0276400	NP_001042728.2
Pan troglodytes (chimpanzee)	PSEN2	XP_003949755.1
Mus musculus (house mouse)	Psen2	NP_001122077.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Psn is required for neuronal survival during aging and normal lifespan.
Title: An Evolutionarily Conserved Role of Presenilin in Neuronal Protection in the Aging

findings suggest that a normal function of presenilin (PS)is to repress kinesin-1 and dynein motor activity during axonal transport of amyloid precursor protein (APP) vesicles; perturbations of APP/PS transport could contribute to early neuropathology observed in Alzheimer's Diseaseprecursor protein (APP) vesicles
Title: Presenilin controls kinesin-1 and dynein function during APP-vesicle transport in vivo.

The interaction of Sanpodo with Presenilin, a component of the gamma-secretase complex, is required for Notch activation.
Title: Sanpodo controls sensory organ precursor fate by directing Notch trafficking and binding ?-secretase.

a conserved role for presenilin in mediating copper uptake
Title: Presenilin promotes dietary copper uptake.

Consistent with its role in Psn processing, Hbs genetically interacts with the Drosophila beta-amyloid protein precursor-like (Appl) protein.
Title: Hibris, a Drosophila nephrin homolog, is required for presenilin-mediated Notch and APP-like cleavages.

The following Psn gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Psn cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OFa19115	NM_001275182.1 Latest version!	Drosophila melanogaster presenilin, transcript variant E (Psn), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
OFa19115	NM_079460.2 Latest version!	Drosophila melanogaster presenilin, transcript variant A (Psn), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
OFa19116	NM_001275181.1 Latest version!	Drosophila melanogaster presenilin, transcript variant D (Psn), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
OFa19116	NM_168856.3 Latest version!	Drosophila melanogaster presenilin, transcript variant B (Psn), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
OFa21131	NM_001144516.2 Latest version!	Drosophila melanogaster presenilin, transcript variant C (Psn), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Psn ( NM_079460.2 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_524184.1 Drosophila melanogaster presenilin, transcript variant A (Psn), mRNA.

Price & Availability↑

CloneID	OFa19115
Clone ID Related Accession (Same CDS sequence)	NM_079460.2 , NM_001275182.1
Accession Version	NM_079460.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1626bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	presenilin, isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_037436). On Nov 6, 2002 this sequence version replaced NM_079460.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGCTGCTG TCAATCTCCA GGCTTCGTGC TCCTCCGGGC TCGCCTCTGA GGATGACGCC 
AATGTGGGCA GCCAGATAGG CGCGGCGGAG CGTTTGGAAC GACCTCCAAG GCGGCAACAG 
CAGCGGAACA ACTACGGCTC CAGCAATCAG GATCAACCGG ATGCTGCCAT ACTTGCTGTG 
CCCAATGTGG TGATGCGTGA ACCTTGTGGC TCGCGCCCTT CAAGACTGAC CGGTGGAGGA 
GGCGGCAGTG GTGGTCCGCC CACAAATGAA ATGGAGGAAG AGCAGGGCCT GAAATACGGG 
GCCCAGCATG TGATCAAGTT ATTCGTCCCC GTCTCCCTTT GCATGCTGGT AGTGGTGGCT 
ACCATCAACT CCATCAGCTT CTACAACAGC ACGGATGTCT ATCTCCTCTA CACACCTTTC 
CATGAACAAT CGCCCGAGCC TAGTGTTAAG TTCTGGAGTG CCTTGGCGAA CTCCCTGATC 
CTGATGAGCG TGGTGGTGGT GATGACCTTT TTGCTGATTG TTTTGTACAA GAAGCGTTGC 
TATCGCATCA TTCACGGCTG GCTGATTCTC TCCTCCTTCA TGTTGTTGTT CATTTTTACG 
TACTTATATT TGGAAGAGCT TCTTCGCGCC TATAACATAC CGATGGACTA CCCTACTGCA 
CTACTGATTA TGTGGAACTT TGGAGTGGTC GGAATGATGT CCATCCATTG GCAGGGACCT 
CTGCGGTTGC AGCAAGGATA TCTCATTTTC GTGGCAGCCT TGATGGCCTT GGTGTTCATT 
AAATACCTGC CTGAATGGAC TGCCTGGGCT GTATTGGCTG CCATTTCTAT TTGGGATCTT 
ATTGCTGTCC TTTCGCCAAG AGGACCCCTC CGCATTCTGG TGGAAACGGC TCAGGAGCGA 
AATGAGCAAA TCTTCCCCGC TCTGATTTAT TCATCCACTG TCGTTTACGC ACTTGTAAAC 
ACTGTTACGC CGCAGCAATC GCAGGCCACA GCTTCCTCCT CGCCGTCGTC CAGCAACTCC 
ACCACAACCA CGAGGGCCAC GCAGAACTCG CTGGCTTCGC CAGAGGCAGC AGCGGCTAGT 
GGCCAACGCA CAGGTAACTC CCATCCTCGA CAGAATCAGC GGGATGACGG CAGTGTACTG 
GCAACTGAAG GTATGCCACT TGTGACTTTT AAAAGCAATT TGCGCGGAAA CGCTGAGGCT 
GCGGGTTTCA CGCAAGAGTG GTCAGCTAAC TTGAGCGAAC GTGTGGCTCG TCGCCAGATT 
GAAGTTCAAA GTACTCAGAG TGGAAACGCT CAGCGCTCCA ACGAGTATAG GACAGTAACA 
GCTCCGGATC AGAATCATCC GGATGGGCAA GAAGAACGTG GCATAAAGCT TGGCCTCGGC 
GACTTCATCT TCTACTCGGT ATTAGTGGGC AAGGCCTCCA GCTACGGCGA CTGGACGACC 
ACAATCGCTT GCTTTGTGGC CATCCTCATT GGACTCTGCC TCACTCTTCT GCTTCTGGCC 
ATTTGGCGCA AGGCGCTACC CGCCCTGCCC ATCTCAATAA CGTTCGGATT GATATTTTGC 
TTCGCCACTA GTGCGGTGGT CAAGCCGTTC ATGGAGGATC TATCGGCCAA GCAGGTGTTT 
ATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_524184.1
CDS	316..1941
Translation	MAAVNLQASCSSGLASEDDANVGSQIGAAERLERPPRRQQQRNNYGSSNQDQPDAAILAVPNVVMREPCGSRPSRLTGGGGGSGGPPTNEMEEEQGLKYGAQHVIKLFVPVSLCMLVVVATINSISFYNSTDVYLLYTPFHEQSPEPSVKFWSALANSLILMSVVVVMTFLLIVLYKKRCYRIIHGWLILSSFMLLFIFTYLYLEELLRAYNIPMDYPTALLIMWNFGVVGMMSIHWQGPLRLQQGYLIFVAALMALVFIKYLPEWTAWAVLAAISIWDLIAVLSPRGPLRILVETAQERNEQIFPALIYSSTVVYALVNTVTPQQSQATASSSPSSSNSTTTTRATQNSLASPEAAAASGQRTGNSHPRQNQRDDGSVLATEGMPLVTFKSNLRGNAEAAGFTQEWSANLSERVARRQIEVQSTQSGNAQRSNEYRTVTAPDQNHPDGQEERGIKLGLGDFIFYSVLVGKASSYGDWTTTIACFVAILIGLCLTLLLLAIWRKALPALPISITFGLIFCFATSAVVKPFMEDLSAKQVFI

Target ORF information:

RefSeq Version	NM_079460.2
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster presenilin, transcript variant A (Psn), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_079460.2

ORF Insert Sequence:

ATGGCTGCTG TCAATCTCCA GGCTTCGTGC TCCTCCGGGC TCGCCTCTGA GGATGACGCC 
AATGTGGGCA GCCAGATAGG CGCGGCGGAG CGTTTGGAAC GACCTCCAAG GCGGCAACAG 
CAGCGGAACA ACTACGGCTC CAGCAATCAG GATCAACCGG ATGCTGCCAT ACTTGCTGTG 
CCCAATGTGG TGATGCGTGA ACCTTGTGGC TCGCGCCCTT CAAGACTGAC CGGTGGAGGA 
GGCGGCAGTG GTGGTCCGCC CACAAATGAA ATGGAGGAAG AGCAGGGCCT GAAATACGGG 
GCCCAGCATG TGATCAAGTT ATTCGTCCCC GTCTCCCTTT GCATGCTGGT AGTGGTGGCT 
ACCATCAACT CCATCAGCTT CTACAACAGC ACGGATGTCT ATCTCCTCTA CACACCTTTC 
CATGAACAAT CGCCCGAGCC TAGTGTTAAG TTCTGGAGTG CCTTGGCGAA CTCCCTGATC 
CTGATGAGCG TGGTGGTGGT GATGACCTTT TTGCTGATTG TTTTGTACAA GAAGCGTTGC 
TATCGCATCA TTCACGGCTG GCTGATTCTC TCCTCCTTCA TGTTGTTGTT CATTTTTACG 
TACTTATATT TGGAAGAGCT TCTTCGCGCC TATAACATAC CGATGGACTA CCCTACTGCA 
CTACTGATTA TGTGGAACTT TGGAGTGGTC GGAATGATGT CCATCCATTG GCAGGGACCT 
CTGCGGTTGC AGCAAGGATA TCTCATTTTC GTGGCAGCCT TGATGGCCTT GGTGTTCATT 
AAATACCTGC CTGAATGGAC TGCCTGGGCT GTATTGGCTG CCATTTCTAT TTGGGATCTT 
ATTGCTGTCC TTTCGCCAAG AGGACCCCTC CGCATTCTGG TGGAAACGGC TCAGGAGCGA 
AATGAGCAAA TCTTCCCCGC TCTGATTTAT TCATCCACTG TCGTTTACGC ACTTGTAAAC 
ACTGTTACGC CGCAGCAATC GCAGGCCACA GCTTCCTCCT CGCCGTCGTC CAGCAACTCC 
ACCACAACCA CGAGGGCCAC GCAGAACTCG CTGGCTTCGC CAGAGGCAGC AGCGGCTAGT 
GGCCAACGCA CAGGTAACTC CCATCCTCGA CAGAATCAGC GGGATGACGG CAGTGTACTG 
GCAACTGAAG GTATGCCACT TGTGACTTTT AAAAGCAATT TGCGCGGAAA CGCTGAGGCT 
GCGGGTTTCA CGCAAGAGTG GTCAGCTAAC TTGAGCGAAC GTGTGGCTCG TCGCCAGATT 
GAAGTTCAAA GTACTCAGAG TGGAAACGCT CAGCGCTCCA ACGAGTATAG GACAGTAACA 
GCTCCGGATC AGAATCATCC GGATGGGCAA GAAGAACGTG GCATAAAGCT TGGCCTCGGC 
GACTTCATCT TCTACTCGGT ATTAGTGGGC AAGGCCTCCA GCTACGGCGA CTGGACGACC 
ACAATCGCTT GCTTTGTGGC CATCCTCATT GGACTCTGCC TCACTCTTCT GCTTCTGGCC 
ATTTGGCGCA AGGCGCTACC CGCCCTGCCC ATCTCAATAA CGTTCGGATT GATATTTTGC 
TTCGCCACTA GTGCGGTGGT CAAGCCGTTC ATGGAGGATC TATCGGCCAA GCAGGTGTTT 
ATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Psn ( NM_001275182.1 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_001262111.1 Drosophila melanogaster presenilin, transcript variant E (Psn), mRNA.

Price & Availability↑

CloneID	OFa19115
Clone ID Related Accession (Same CDS sequence)	NM_079460.2 , NM_001275182.1
Accession Version	NM_001275182.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1626bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	presenilin, isoform E
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_037436). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGCTGCTG TCAATCTCCA GGCTTCGTGC TCCTCCGGGC TCGCCTCTGA GGATGACGCC 
AATGTGGGCA GCCAGATAGG CGCGGCGGAG CGTTTGGAAC GACCTCCAAG GCGGCAACAG 
CAGCGGAACA ACTACGGCTC CAGCAATCAG GATCAACCGG ATGCTGCCAT ACTTGCTGTG 
CCCAATGTGG TGATGCGTGA ACCTTGTGGC TCGCGCCCTT CAAGACTGAC CGGTGGAGGA 
GGCGGCAGTG GTGGTCCGCC CACAAATGAA ATGGAGGAAG AGCAGGGCCT GAAATACGGG 
GCCCAGCATG TGATCAAGTT ATTCGTCCCC GTCTCCCTTT GCATGCTGGT AGTGGTGGCT 
ACCATCAACT CCATCAGCTT CTACAACAGC ACGGATGTCT ATCTCCTCTA CACACCTTTC 
CATGAACAAT CGCCCGAGCC TAGTGTTAAG TTCTGGAGTG CCTTGGCGAA CTCCCTGATC 
CTGATGAGCG TGGTGGTGGT GATGACCTTT TTGCTGATTG TTTTGTACAA GAAGCGTTGC 
TATCGCATCA TTCACGGCTG GCTGATTCTC TCCTCCTTCA TGTTGTTGTT CATTTTTACG 
TACTTATATT TGGAAGAGCT TCTTCGCGCC TATAACATAC CGATGGACTA CCCTACTGCA 
CTACTGATTA TGTGGAACTT TGGAGTGGTC GGAATGATGT CCATCCATTG GCAGGGACCT 
CTGCGGTTGC AGCAAGGATA TCTCATTTTC GTGGCAGCCT TGATGGCCTT GGTGTTCATT 
AAATACCTGC CTGAATGGAC TGCCTGGGCT GTATTGGCTG CCATTTCTAT TTGGGATCTT 
ATTGCTGTCC TTTCGCCAAG AGGACCCCTC CGCATTCTGG TGGAAACGGC TCAGGAGCGA 
AATGAGCAAA TCTTCCCCGC TCTGATTTAT TCATCCACTG TCGTTTACGC ACTTGTAAAC 
ACTGTTACGC CGCAGCAATC GCAGGCCACA GCTTCCTCCT CGCCGTCGTC CAGCAACTCC 
ACCACAACCA CGAGGGCCAC GCAGAACTCG CTGGCTTCGC CAGAGGCAGC AGCGGCTAGT 
GGCCAACGCA CAGGTAACTC CCATCCTCGA CAGAATCAGC GGGATGACGG CAGTGTACTG 
GCAACTGAAG GTATGCCACT TGTGACTTTT AAAAGCAATT TGCGCGGAAA CGCTGAGGCT 
GCGGGTTTCA CGCAAGAGTG GTCAGCTAAC TTGAGCGAAC GTGTGGCTCG TCGCCAGATT 
GAAGTTCAAA GTACTCAGAG TGGAAACGCT CAGCGCTCCA ACGAGTATAG GACAGTAACA 
GCTCCGGATC AGAATCATCC GGATGGGCAA GAAGAACGTG GCATAAAGCT TGGCCTCGGC 
GACTTCATCT TCTACTCGGT ATTAGTGGGC AAGGCCTCCA GCTACGGCGA CTGGACGACC 
ACAATCGCTT GCTTTGTGGC CATCCTCATT GGACTCTGCC TCACTCTTCT GCTTCTGGCC 
ATTTGGCGCA AGGCGCTACC CGCCCTGCCC ATCTCAATAA CGTTCGGATT GATATTTTGC 
TTCGCCACTA GTGCGGTGGT CAAGCCGTTC ATGGAGGATC TATCGGCCAA GCAGGTGTTT 
ATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001262111.1
CDS	159..1784
Translation	MAAVNLQASCSSGLASEDDANVGSQIGAAERLERPPRRQQQRNNYGSSNQDQPDAAILAVPNVVMREPCGSRPSRLTGGGGGSGGPPTNEMEEEQGLKYGAQHVIKLFVPVSLCMLVVVATINSISFYNSTDVYLLYTPFHEQSPEPSVKFWSALANSLILMSVVVVMTFLLIVLYKKRCYRIIHGWLILSSFMLLFIFTYLYLEELLRAYNIPMDYPTALLIMWNFGVVGMMSIHWQGPLRLQQGYLIFVAALMALVFIKYLPEWTAWAVLAAISIWDLIAVLSPRGPLRILVETAQERNEQIFPALIYSSTVVYALVNTVTPQQSQATASSSPSSSNSTTTTRATQNSLASPEAAAASGQRTGNSHPRQNQRDDGSVLATEGMPLVTFKSNLRGNAEAAGFTQEWSANLSERVARRQIEVQSTQSGNAQRSNEYRTVTAPDQNHPDGQEERGIKLGLGDFIFYSVLVGKASSYGDWTTTIACFVAILIGLCLTLLLLAIWRKALPALPISITFGLIFCFATSAVVKPFMEDLSAKQVFI

Target ORF information:

RefSeq Version	NM_001275182.1
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster presenilin, transcript variant E (Psn), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001275182.1

ORF Insert Sequence:

ATGGCTGCTG TCAATCTCCA GGCTTCGTGC TCCTCCGGGC TCGCCTCTGA GGATGACGCC 
AATGTGGGCA GCCAGATAGG CGCGGCGGAG CGTTTGGAAC GACCTCCAAG GCGGCAACAG 
CAGCGGAACA ACTACGGCTC CAGCAATCAG GATCAACCGG ATGCTGCCAT ACTTGCTGTG 
CCCAATGTGG TGATGCGTGA ACCTTGTGGC TCGCGCCCTT CAAGACTGAC CGGTGGAGGA 
GGCGGCAGTG GTGGTCCGCC CACAAATGAA ATGGAGGAAG AGCAGGGCCT GAAATACGGG 
GCCCAGCATG TGATCAAGTT ATTCGTCCCC GTCTCCCTTT GCATGCTGGT AGTGGTGGCT 
ACCATCAACT CCATCAGCTT CTACAACAGC ACGGATGTCT ATCTCCTCTA CACACCTTTC 
CATGAACAAT CGCCCGAGCC TAGTGTTAAG TTCTGGAGTG CCTTGGCGAA CTCCCTGATC 
CTGATGAGCG TGGTGGTGGT GATGACCTTT TTGCTGATTG TTTTGTACAA GAAGCGTTGC 
TATCGCATCA TTCACGGCTG GCTGATTCTC TCCTCCTTCA TGTTGTTGTT CATTTTTACG 
TACTTATATT TGGAAGAGCT TCTTCGCGCC TATAACATAC CGATGGACTA CCCTACTGCA 
CTACTGATTA TGTGGAACTT TGGAGTGGTC GGAATGATGT CCATCCATTG GCAGGGACCT 
CTGCGGTTGC AGCAAGGATA TCTCATTTTC GTGGCAGCCT TGATGGCCTT GGTGTTCATT 
AAATACCTGC CTGAATGGAC TGCCTGGGCT GTATTGGCTG CCATTTCTAT TTGGGATCTT 
ATTGCTGTCC TTTCGCCAAG AGGACCCCTC CGCATTCTGG TGGAAACGGC TCAGGAGCGA 
AATGAGCAAA TCTTCCCCGC TCTGATTTAT TCATCCACTG TCGTTTACGC ACTTGTAAAC 
ACTGTTACGC CGCAGCAATC GCAGGCCACA GCTTCCTCCT CGCCGTCGTC CAGCAACTCC 
ACCACAACCA CGAGGGCCAC GCAGAACTCG CTGGCTTCGC CAGAGGCAGC AGCGGCTAGT 
GGCCAACGCA CAGGTAACTC CCATCCTCGA CAGAATCAGC GGGATGACGG CAGTGTACTG 
GCAACTGAAG GTATGCCACT TGTGACTTTT AAAAGCAATT TGCGCGGAAA CGCTGAGGCT 
GCGGGTTTCA CGCAAGAGTG GTCAGCTAAC TTGAGCGAAC GTGTGGCTCG TCGCCAGATT 
GAAGTTCAAA GTACTCAGAG TGGAAACGCT CAGCGCTCCA ACGAGTATAG GACAGTAACA 
GCTCCGGATC AGAATCATCC GGATGGGCAA GAAGAACGTG GCATAAAGCT TGGCCTCGGC 
GACTTCATCT TCTACTCGGT ATTAGTGGGC AAGGCCTCCA GCTACGGCGA CTGGACGACC 
ACAATCGCTT GCTTTGTGGC CATCCTCATT GGACTCTGCC TCACTCTTCT GCTTCTGGCC 
ATTTGGCGCA AGGCGCTACC CGCCCTGCCC ATCTCAATAA CGTTCGGATT GATATTTTGC 
TTCGCCACTA GTGCGGTGGT CAAGCCGTTC ATGGAGGATC TATCGGCCAA GCAGGTGTTT 
ATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Psn ( NM_001275181.1 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_001262110.1 Drosophila melanogaster presenilin, transcript variant D (Psn), mRNA.

Price & Availability↑

CloneID	OFa19116
Clone ID Related Accession (Same CDS sequence)	NM_001275181.1 , NM_168856.3
Accession Version	NM_001275181.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1584bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	presenilin, isoform D
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_037436). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGCTGCTG TCAATCTCCA GGCTTCGTGC TCCTCCGGGC TCGCCTCTGA GGATGACGCC 
AATGTGGGCA GCCAGATAGG CGCGGCGGAG CGTTTGGAAC GACCTCCAAG GCGGCAACAG 
CAGCGGAACA ACTACGGCTC CAGCAATCAG GATCAACCGG ATGCTGCCAT ACTTGCTGTG 
CCCAATGTGG TGATGCGTGA ACCTTGTGGC TCGCGCCCTT CAAGACTGAC CGGTGGAGGA 
GGCGGCAGTG GTGGTCCGCC CACAAATGAA ATGGAGGAAG AGCAGGGCCT GAAATACGGG 
GCCCAGCATG TGATCAAGTT ATTCGTCCCC GTCTCCCTTT GCATGCTGGT AGTGGTGGCT 
ACCATCAACT CCATCAGCTT CTACAACAGC ACGGATGTCT ATCTCCTCTA CACACCTTTC 
CATGAACAAT CGCCCGAGCC TAGTGTTAAG TTCTGGAGTG CCTTGGCGAA CTCCCTGATC 
CTGATGAGCG TGGTGGTGGT GATGACCTTT TTGCTGATTG TTTTGTACAA GAAGCGTTGC 
TATCGCATCA TTCACGGCTG GCTGATTCTC TCCTCCTTCA TGTTGTTGTT CATTTTTACG 
TACTTATATT TGGAAGAGCT TCTTCGCGCC TATAACATAC CGATGGACTA CCCTACTGCA 
CTACTGATTA TGTGGAACTT TGGAGTGGTC GGAATGATGT CCATCCATTG GCAGGGACCT 
CTGCGGTTGC AGCAAGGATA TCTCATTTTC GTGGCAGCCT TGATGGCCTT GGTGTTCATT 
AAATACCTGC CTGAATGGAC TGCCTGGGCT GTATTGGCTG CCATTTCTAT TTGGGATCTT 
ATTGCTGTCC TTTCGCCAAG AGGACCCCTC CGCATTCTGG TGGAAACGGC TCAGGAGCGA 
AATGAGCAAA TCTTCCCCGC TCTGATTTAT TCATCCACTG TCGTTTACGC ACTTGTAAAC 
ACTGTTACGC CGCAGCAATC GCAGGCCACA GCTTCCTCCT CGCCGTCGTC CAGCAACTCC 
ACCACAACCA CGAGGGCCAC GCAGAACTCG CTGGCTTCGC CAGAGGCAGC AGCGGCTAGT 
GGCCAACGCA CAGGTAACTC CCATCCTCGA CAGAATCAGC GGGATGACGG CAGTGTACTG 
GCAACTGAAG CTGAGGCTGC GGGTTTCACG CAAGAGTGGT CAGCTAACTT GAGCGAACGT 
GTGGCTCGTC GCCAGATTGA AGTTCAAAGT ACTCAGAGTG GAAACGCTCA GCGCTCCAAC 
GAGTATAGGA CAGTAACAGC TCCGGATCAG AATCATCCGG ATGGGCAAGA AGAACGTGGC 
ATAAAGCTTG GCCTCGGCGA CTTCATCTTC TACTCGGTAT TAGTGGGCAA GGCCTCCAGC 
TACGGCGACT GGACGACCAC AATCGCTTGC TTTGTGGCCA TCCTCATTGG ACTCTGCCTC 
ACTCTTCTGC TTCTGGCCAT TTGGCGCAAG GCGCTACCCG CCCTGCCCAT CTCAATAACG 
TTCGGATTGA TATTTTGCTT CGCCACTAGT GCGGTGGTCA AGCCGTTCAT GGAGGATCTA 
TCGGCCAAGC AGGTGTTTAT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001262110.1
CDS	189..1772
Translation	MAAVNLQASCSSGLASEDDANVGSQIGAAERLERPPRRQQQRNNYGSSNQDQPDAAILAVPNVVMREPCGSRPSRLTGGGGGSGGPPTNEMEEEQGLKYGAQHVIKLFVPVSLCMLVVVATINSISFYNSTDVYLLYTPFHEQSPEPSVKFWSALANSLILMSVVVVMTFLLIVLYKKRCYRIIHGWLILSSFMLLFIFTYLYLEELLRAYNIPMDYPTALLIMWNFGVVGMMSIHWQGPLRLQQGYLIFVAALMALVFIKYLPEWTAWAVLAAISIWDLIAVLSPRGPLRILVETAQERNEQIFPALIYSSTVVYALVNTVTPQQSQATASSSPSSSNSTTTTRATQNSLASPEAAAASGQRTGNSHPRQNQRDDGSVLATEAEAAGFTQEWSANLSERVARRQIEVQSTQSGNAQRSNEYRTVTAPDQNHPDGQEERGIKLGLGDFIFYSVLVGKASSYGDWTTTIACFVAILIGLCLTLLLLAIWRKALPALPISITFGLIFCFATSAVVKPFMEDLSAKQVFI

Target ORF information:

RefSeq Version	NM_001275181.1
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster presenilin, transcript variant D (Psn), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001275181.1

ORF Insert Sequence:

ATGGCTGCTG TCAATCTCCA GGCTTCGTGC TCCTCCGGGC TCGCCTCTGA GGATGACGCC 
AATGTGGGCA GCCAGATAGG CGCGGCGGAG CGTTTGGAAC GACCTCCAAG GCGGCAACAG 
CAGCGGAACA ACTACGGCTC CAGCAATCAG GATCAACCGG ATGCTGCCAT ACTTGCTGTG 
CCCAATGTGG TGATGCGTGA ACCTTGTGGC TCGCGCCCTT CAAGACTGAC CGGTGGAGGA 
GGCGGCAGTG GTGGTCCGCC CACAAATGAA ATGGAGGAAG AGCAGGGCCT GAAATACGGG 
GCCCAGCATG TGATCAAGTT ATTCGTCCCC GTCTCCCTTT GCATGCTGGT AGTGGTGGCT 
ACCATCAACT CCATCAGCTT CTACAACAGC ACGGATGTCT ATCTCCTCTA CACACCTTTC 
CATGAACAAT CGCCCGAGCC TAGTGTTAAG TTCTGGAGTG CCTTGGCGAA CTCCCTGATC 
CTGATGAGCG TGGTGGTGGT GATGACCTTT TTGCTGATTG TTTTGTACAA GAAGCGTTGC 
TATCGCATCA TTCACGGCTG GCTGATTCTC TCCTCCTTCA TGTTGTTGTT CATTTTTACG 
TACTTATATT TGGAAGAGCT TCTTCGCGCC TATAACATAC CGATGGACTA CCCTACTGCA 
CTACTGATTA TGTGGAACTT TGGAGTGGTC GGAATGATGT CCATCCATTG GCAGGGACCT 
CTGCGGTTGC AGCAAGGATA TCTCATTTTC GTGGCAGCCT TGATGGCCTT GGTGTTCATT 
AAATACCTGC CTGAATGGAC TGCCTGGGCT GTATTGGCTG CCATTTCTAT TTGGGATCTT 
ATTGCTGTCC TTTCGCCAAG AGGACCCCTC CGCATTCTGG TGGAAACGGC TCAGGAGCGA 
AATGAGCAAA TCTTCCCCGC TCTGATTTAT TCATCCACTG TCGTTTACGC ACTTGTAAAC 
ACTGTTACGC CGCAGCAATC GCAGGCCACA GCTTCCTCCT CGCCGTCGTC CAGCAACTCC 
ACCACAACCA CGAGGGCCAC GCAGAACTCG CTGGCTTCGC CAGAGGCAGC AGCGGCTAGT 
GGCCAACGCA CAGGTAACTC CCATCCTCGA CAGAATCAGC GGGATGACGG CAGTGTACTG 
GCAACTGAAG CTGAGGCTGC GGGTTTCACG CAAGAGTGGT CAGCTAACTT GAGCGAACGT 
GTGGCTCGTC GCCAGATTGA AGTTCAAAGT ACTCAGAGTG GAAACGCTCA GCGCTCCAAC 
GAGTATAGGA CAGTAACAGC TCCGGATCAG AATCATCCGG ATGGGCAAGA AGAACGTGGC 
ATAAAGCTTG GCCTCGGCGA CTTCATCTTC TACTCGGTAT TAGTGGGCAA GGCCTCCAGC 
TACGGCGACT GGACGACCAC AATCGCTTGC TTTGTGGCCA TCCTCATTGG ACTCTGCCTC 
ACTCTTCTGC TTCTGGCCAT TTGGCGCAAG GCGCTACCCG CCCTGCCCAT CTCAATAACG 
TTCGGATTGA TATTTTGCTT CGCCACTAGT GCGGTGGTCA AGCCGTTCAT GGAGGATCTA 
TCGGCCAAGC AGGTGTTTAT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Psn ( NM_168856.3 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_730535.1 Drosophila melanogaster presenilin, transcript variant B (Psn), mRNA.

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CloneID	OFa19116
Clone ID Related Accession (Same CDS sequence)	NM_001275181.1 , NM_168856.3
Accession Version	NM_168856.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1584bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	presenilin, isoform B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_037436). On Jan 16, 2013 this sequence version replaced NM_168856.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGCTGCTG TCAATCTCCA GGCTTCGTGC TCCTCCGGGC TCGCCTCTGA GGATGACGCC 
AATGTGGGCA GCCAGATAGG CGCGGCGGAG CGTTTGGAAC GACCTCCAAG GCGGCAACAG 
CAGCGGAACA ACTACGGCTC CAGCAATCAG GATCAACCGG ATGCTGCCAT ACTTGCTGTG 
CCCAATGTGG TGATGCGTGA ACCTTGTGGC TCGCGCCCTT CAAGACTGAC CGGTGGAGGA 
GGCGGCAGTG GTGGTCCGCC CACAAATGAA ATGGAGGAAG AGCAGGGCCT GAAATACGGG 
GCCCAGCATG TGATCAAGTT ATTCGTCCCC GTCTCCCTTT GCATGCTGGT AGTGGTGGCT 
ACCATCAACT CCATCAGCTT CTACAACAGC ACGGATGTCT ATCTCCTCTA CACACCTTTC 
CATGAACAAT CGCCCGAGCC TAGTGTTAAG TTCTGGAGTG CCTTGGCGAA CTCCCTGATC 
CTGATGAGCG TGGTGGTGGT GATGACCTTT TTGCTGATTG TTTTGTACAA GAAGCGTTGC 
TATCGCATCA TTCACGGCTG GCTGATTCTC TCCTCCTTCA TGTTGTTGTT CATTTTTACG 
TACTTATATT TGGAAGAGCT TCTTCGCGCC TATAACATAC CGATGGACTA CCCTACTGCA 
CTACTGATTA TGTGGAACTT TGGAGTGGTC GGAATGATGT CCATCCATTG GCAGGGACCT 
CTGCGGTTGC AGCAAGGATA TCTCATTTTC GTGGCAGCCT TGATGGCCTT GGTGTTCATT 
AAATACCTGC CTGAATGGAC TGCCTGGGCT GTATTGGCTG CCATTTCTAT TTGGGATCTT 
ATTGCTGTCC TTTCGCCAAG AGGACCCCTC CGCATTCTGG TGGAAACGGC TCAGGAGCGA 
AATGAGCAAA TCTTCCCCGC TCTGATTTAT TCATCCACTG TCGTTTACGC ACTTGTAAAC 
ACTGTTACGC CGCAGCAATC GCAGGCCACA GCTTCCTCCT CGCCGTCGTC CAGCAACTCC 
ACCACAACCA CGAGGGCCAC GCAGAACTCG CTGGCTTCGC CAGAGGCAGC AGCGGCTAGT 
GGCCAACGCA CAGGTAACTC CCATCCTCGA CAGAATCAGC GGGATGACGG CAGTGTACTG 
GCAACTGAAG CTGAGGCTGC GGGTTTCACG CAAGAGTGGT CAGCTAACTT GAGCGAACGT 
GTGGCTCGTC GCCAGATTGA AGTTCAAAGT ACTCAGAGTG GAAACGCTCA GCGCTCCAAC 
GAGTATAGGA CAGTAACAGC TCCGGATCAG AATCATCCGG ATGGGCAAGA AGAACGTGGC 
ATAAAGCTTG GCCTCGGCGA CTTCATCTTC TACTCGGTAT TAGTGGGCAA GGCCTCCAGC 
TACGGCGACT GGACGACCAC AATCGCTTGC TTTGTGGCCA TCCTCATTGG ACTCTGCCTC 
ACTCTTCTGC TTCTGGCCAT TTGGCGCAAG GCGCTACCCG CCCTGCCCAT CTCAATAACG 
TTCGGATTGA TATTTTGCTT CGCCACTAGT GCGGTGGTCA AGCCGTTCAT GGAGGATCTA 
TCGGCCAAGC AGGTGTTTAT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_730535.1
CDS	159..1742
Translation	MAAVNLQASCSSGLASEDDANVGSQIGAAERLERPPRRQQQRNNYGSSNQDQPDAAILAVPNVVMREPCGSRPSRLTGGGGGSGGPPTNEMEEEQGLKYGAQHVIKLFVPVSLCMLVVVATINSISFYNSTDVYLLYTPFHEQSPEPSVKFWSALANSLILMSVVVVMTFLLIVLYKKRCYRIIHGWLILSSFMLLFIFTYLYLEELLRAYNIPMDYPTALLIMWNFGVVGMMSIHWQGPLRLQQGYLIFVAALMALVFIKYLPEWTAWAVLAAISIWDLIAVLSPRGPLRILVETAQERNEQIFPALIYSSTVVYALVNTVTPQQSQATASSSPSSSNSTTTTRATQNSLASPEAAAASGQRTGNSHPRQNQRDDGSVLATEAEAAGFTQEWSANLSERVARRQIEVQSTQSGNAQRSNEYRTVTAPDQNHPDGQEERGIKLGLGDFIFYSVLVGKASSYGDWTTTIACFVAILIGLCLTLLLLAIWRKALPALPISITFGLIFCFATSAVVKPFMEDLSAKQVFI

Target ORF information:

RefSeq Version	NM_168856.3
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster presenilin, transcript variant B (Psn), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_168856.3

ORF Insert Sequence:

ATGGCTGCTG TCAATCTCCA GGCTTCGTGC TCCTCCGGGC TCGCCTCTGA GGATGACGCC 
AATGTGGGCA GCCAGATAGG CGCGGCGGAG CGTTTGGAAC GACCTCCAAG GCGGCAACAG 
CAGCGGAACA ACTACGGCTC CAGCAATCAG GATCAACCGG ATGCTGCCAT ACTTGCTGTG 
CCCAATGTGG TGATGCGTGA ACCTTGTGGC TCGCGCCCTT CAAGACTGAC CGGTGGAGGA 
GGCGGCAGTG GTGGTCCGCC CACAAATGAA ATGGAGGAAG AGCAGGGCCT GAAATACGGG 
GCCCAGCATG TGATCAAGTT ATTCGTCCCC GTCTCCCTTT GCATGCTGGT AGTGGTGGCT 
ACCATCAACT CCATCAGCTT CTACAACAGC ACGGATGTCT ATCTCCTCTA CACACCTTTC 
CATGAACAAT CGCCCGAGCC TAGTGTTAAG TTCTGGAGTG CCTTGGCGAA CTCCCTGATC 
CTGATGAGCG TGGTGGTGGT GATGACCTTT TTGCTGATTG TTTTGTACAA GAAGCGTTGC 
TATCGCATCA TTCACGGCTG GCTGATTCTC TCCTCCTTCA TGTTGTTGTT CATTTTTACG 
TACTTATATT TGGAAGAGCT TCTTCGCGCC TATAACATAC CGATGGACTA CCCTACTGCA 
CTACTGATTA TGTGGAACTT TGGAGTGGTC GGAATGATGT CCATCCATTG GCAGGGACCT 
CTGCGGTTGC AGCAAGGATA TCTCATTTTC GTGGCAGCCT TGATGGCCTT GGTGTTCATT 
AAATACCTGC CTGAATGGAC TGCCTGGGCT GTATTGGCTG CCATTTCTAT TTGGGATCTT 
ATTGCTGTCC TTTCGCCAAG AGGACCCCTC CGCATTCTGG TGGAAACGGC TCAGGAGCGA 
AATGAGCAAA TCTTCCCCGC TCTGATTTAT TCATCCACTG TCGTTTACGC ACTTGTAAAC 
ACTGTTACGC CGCAGCAATC GCAGGCCACA GCTTCCTCCT CGCCGTCGTC CAGCAACTCC 
ACCACAACCA CGAGGGCCAC GCAGAACTCG CTGGCTTCGC CAGAGGCAGC AGCGGCTAGT 
GGCCAACGCA CAGGTAACTC CCATCCTCGA CAGAATCAGC GGGATGACGG CAGTGTACTG 
GCAACTGAAG CTGAGGCTGC GGGTTTCACG CAAGAGTGGT CAGCTAACTT GAGCGAACGT 
GTGGCTCGTC GCCAGATTGA AGTTCAAAGT ACTCAGAGTG GAAACGCTCA GCGCTCCAAC 
GAGTATAGGA CAGTAACAGC TCCGGATCAG AATCATCCGG ATGGGCAAGA AGAACGTGGC 
ATAAAGCTTG GCCTCGGCGA CTTCATCTTC TACTCGGTAT TAGTGGGCAA GGCCTCCAGC 
TACGGCGACT GGACGACCAC AATCGCTTGC TTTGTGGCCA TCCTCATTGG ACTCTGCCTC 
ACTCTTCTGC TTCTGGCCAT TTGGCGCAAG GCGCTACCCG CCCTGCCCAT CTCAATAACG 
TTCGGATTGA TATTTTGCTT CGCCACTAGT GCGGTGGTCA AGCCGTTCAT GGAGGATCTA 
TCGGCCAAGC AGGTGTTTAT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Psn ( NM_001144516.2 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_001137988.1 Drosophila melanogaster presenilin, transcript variant C (Psn), mRNA.

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CloneID	OFa21131
Clone ID Related Accession (Same CDS sequence)	NM_001144516.2
Accession Version	NM_001144516.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1527bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	presenilin, isoform C
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_037436). On May 8, 2012 this sequence version replaced NM_001144516.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGCTGCTG TCAATCTCCA GGCTTCGTGC TCCTCCGGGC TCGCCTCTGA GGATGACGCC 
AATGTGGGCA GCCAGATAGG CGCGGCGGAG CGTTTGGAAC GACCTCCAAG GCGGCAACAG 
CAGCGGAACA ACTACGGCTC CAGCAATCAG GATCAACCGG ATGCTGCCAT ACTTGCTGTG 
CCCAATGTGG TGATGCGTGA ACCTTGTGGC TCGCGCCCTT CAAGACTGAC CGGTGGAGGA 
GGCGGCAGTG GTGGTCCGCC CACAAATGAA ATGGAGGAAG AGCAGGGCCT GAAATACGGG 
GCCCAGCATG TGATCAAGTT ATTCGTCCCC GTCTCCCTTT GCATGCTGGT AGTGGTGGCT 
ACCATCAACT CCATCAGCTT CTACAACAGC ACGGATGTCT ATCTCCTCTA CACACCTTTC 
CATGAACAAT CGCCCGAGCC TAGTGTTAAG TTCTGGAGTG CCTTGGCGAA CTCCCTGATC 
CTGATGAGCG TGGTGGTGGT GATGACCTTT TTGCTGATTG TTTTGTACAA GAAGCGTTGC 
TATCGCATCA TTCACGGCTG GCTGATTCTC TCCTCCTTCA TGTTGTTGTT CATTTTTACG 
TACTTATATT TGGAAGAGCT TCTTCGCGCC TATAACATAC CGATGGACTA CCCTACTGCA 
CTACTGATTA TGTGGAACTT TGGAGTGGTC GGAATGATGT CCATCCATTG GCAGGGACCT 
CTGCGGTTGC AGCAAGGATA TCTCATTTTC GTGGCAGCCT TGATGGCCTT GGTGTTCATT 
AAATACCTGC CTGAATGGAC TGCCTGGGCT GTATTGGCTG CCATTTCTAT TTGGGATCTT 
ATTGCTGTCC TTTCGCCAAG AGGACCCCTC CGCATTCTGG TGGAAACGGC TCAGGAGCGA 
AATGAGCAAA TCTTCCCCGC TCTGATTTAT TCATCCACTG TCGTTTACGC ACTTGTAAAC 
ACTGTTACGC CGCAGCAATC GCAGGCCACA GCTTCCTCCT CGCCGTCGTC CAGCAACTCC 
ACCACAACCA CGAGGGCCAC GCAGAACTCG CTGGCTTCGC CAGAGGCAGC AGCGGCTAGT 
GGCCAACGCA CAGCTGAGGC TGCGGGTTTC ACGCAAGAGT GGTCAGCTAA CTTGAGCGAA 
CGTGTGGCTC GTCGCCAGAT TGAAGTTCAA AGTACTCAGA GTGGAAACGC TCAGCGCTCC 
AACGAGTATA GGACAGTAAC AGCTCCGGAT CAGAATCATC CGGATGGGCA AGAAGAACGT 
GGCATAAAGC TTGGCCTCGG CGACTTCATC TTCTACTCGG TATTAGTGGG CAAGGCCTCC 
AGCTACGGCG ACTGGACGAC CACAATCGCT TGCTTTGTGG CCATCCTCAT TGGACTCTGC 
CTCACTCTTC TGCTTCTGGC CATTTGGCGC AAGGCGCTAC CCGCCCTGCC CATCTCAATA 
ACGTTCGGAT TGATATTTTG CTTCGCCACT AGTGCGGTGG TCAAGCCGTT CATGGAGGAT 
CTATCGGCCA AGCAGGTGTT TATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001137988.1
CDS	145..1671
Translation	MAAVNLQASCSSGLASEDDANVGSQIGAAERLERPPRRQQQRNNYGSSNQDQPDAAILAVPNVVMREPCGSRPSRLTGGGGGSGGPPTNEMEEEQGLKYGAQHVIKLFVPVSLCMLVVVATINSISFYNSTDVYLLYTPFHEQSPEPSVKFWSALANSLILMSVVVVMTFLLIVLYKKRCYRIIHGWLILSSFMLLFIFTYLYLEELLRAYNIPMDYPTALLIMWNFGVVGMMSIHWQGPLRLQQGYLIFVAALMALVFIKYLPEWTAWAVLAAISIWDLIAVLSPRGPLRILVETAQERNEQIFPALIYSSTVVYALVNTVTPQQSQATASSSPSSSNSTTTTRATQNSLASPEAAAASGQRTAEAAGFTQEWSANLSERVARRQIEVQSTQSGNAQRSNEYRTVTAPDQNHPDGQEERGIKLGLGDFIFYSVLVGKASSYGDWTTTIACFVAILIGLCLTLLLLAIWRKALPALPISITFGLIFCFATSAVVKPFMEDLSAKQVFI

Target ORF information:

RefSeq Version	NM_001144516.2
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster presenilin, transcript variant C (Psn), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001144516.2

ORF Insert Sequence:

ATGGCTGCTG TCAATCTCCA GGCTTCGTGC TCCTCCGGGC TCGCCTCTGA GGATGACGCC 
AATGTGGGCA GCCAGATAGG CGCGGCGGAG CGTTTGGAAC GACCTCCAAG GCGGCAACAG 
CAGCGGAACA ACTACGGCTC CAGCAATCAG GATCAACCGG ATGCTGCCAT ACTTGCTGTG 
CCCAATGTGG TGATGCGTGA ACCTTGTGGC TCGCGCCCTT CAAGACTGAC CGGTGGAGGA 
GGCGGCAGTG GTGGTCCGCC CACAAATGAA ATGGAGGAAG AGCAGGGCCT GAAATACGGG 
GCCCAGCATG TGATCAAGTT ATTCGTCCCC GTCTCCCTTT GCATGCTGGT AGTGGTGGCT 
ACCATCAACT CCATCAGCTT CTACAACAGC ACGGATGTCT ATCTCCTCTA CACACCTTTC 
CATGAACAAT CGCCCGAGCC TAGTGTTAAG TTCTGGAGTG CCTTGGCGAA CTCCCTGATC 
CTGATGAGCG TGGTGGTGGT GATGACCTTT TTGCTGATTG TTTTGTACAA GAAGCGTTGC 
TATCGCATCA TTCACGGCTG GCTGATTCTC TCCTCCTTCA TGTTGTTGTT CATTTTTACG 
TACTTATATT TGGAAGAGCT TCTTCGCGCC TATAACATAC CGATGGACTA CCCTACTGCA 
CTACTGATTA TGTGGAACTT TGGAGTGGTC GGAATGATGT CCATCCATTG GCAGGGACCT 
CTGCGGTTGC AGCAAGGATA TCTCATTTTC GTGGCAGCCT TGATGGCCTT GGTGTTCATT 
AAATACCTGC CTGAATGGAC TGCCTGGGCT GTATTGGCTG CCATTTCTAT TTGGGATCTT 
ATTGCTGTCC TTTCGCCAAG AGGACCCCTC CGCATTCTGG TGGAAACGGC TCAGGAGCGA 
AATGAGCAAA TCTTCCCCGC TCTGATTTAT TCATCCACTG TCGTTTACGC ACTTGTAAAC 
ACTGTTACGC CGCAGCAATC GCAGGCCACA GCTTCCTCCT CGCCGTCGTC CAGCAACTCC 
ACCACAACCA CGAGGGCCAC GCAGAACTCG CTGGCTTCGC CAGAGGCAGC AGCGGCTAGT 
GGCCAACGCA CAGCTGAGGC TGCGGGTTTC ACGCAAGAGT GGTCAGCTAA CTTGAGCGAA 
CGTGTGGCTC GTCGCCAGAT TGAAGTTCAA AGTACTCAGA GTGGAAACGC TCAGCGCTCC 
AACGAGTATA GGACAGTAAC AGCTCCGGAT CAGAATCATC CGGATGGGCA AGAAGAACGT 
GGCATAAAGC TTGGCCTCGG CGACTTCATC TTCTACTCGG TATTAGTGGG CAAGGCCTCC 
AGCTACGGCG ACTGGACGAC CACAATCGCT TGCTTTGTGG CCATCCTCAT TGGACTCTGC 
CTCACTCTTC TGCTTCTGGC CATTTGGCGC AAGGCGCTAC CCGCCCTGCC CATCTCAATA 
ACGTTCGGAT TGATATTTTG CTTCGCCACT AGTGCGGTGG TCAAGCCGTT CATGGAGGAT 
CTATCGGCCA AGCAGGTGTT TATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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Psn cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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