aos cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	aos
Entrez Gene ID	39833
Full Name	argos
Synonyms	Aos,Argos,CG4531,DmAos,Dmel\CG4531,arg,gil,l(3)05845,l(3)05959,l(3)j5E11,l(3)rJ472,l(3)rJ812,l(3)rQ526,rlt,sty
General protein information	Preferred Names argos Names CG4531 gene product from transcript CG4531-RA CG4531-PA aos-PA giant lens roulette strawberry
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 3L Map Location: 73A2-73A2

mRNA and Protein(s)

mRNA	Protein	Name
NM_079383.3	NP_524107.2	argos

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

argos is upregulated by Notch in adult muscle progenitors but is repressed in the wing
Title: Context-dependent enhancer selection confers alternate modes of notch regulation on argos.

1.6-A resolution crystal structure of Argos bound to an EGFR ligand
Title: Structural basis for EGFR ligand sequestration by Argos.

Argos mutants are deficient in their ability to bind Spitz in vitro
Title: Argos mutants define an affinity threshold for spitz inhibition in vivo.

Computational analysis was performed on EGFR inhibition by argos.
Title: Computational analysis of EGFR inhibition by Argos.

Argos inhibits EGFR (DER) signalling without interacting directly with the receptor, but instead by sequestering the DER-activating ligand Spitz
Title: Argos inhibits epidermal growth factor receptor signalling by ligand sequestration.

The following aos gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the aos cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa18704	NM_079383.3 Latest version!	Drosophila melanogaster argos (aos), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

aos ( NM_079383.3 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_524107.2 Drosophila melanogaster argos (aos), mRNA.

Price & Availability↑

CloneID	OFa18704
Clone ID Related Accession (Same CDS sequence)	NM_079383.3
Accession Version	NM_079383.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1335bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	argos
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_037436). On Jan 16, 2013 this sequence version replaced NM_079383.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGCCTACGA CATTGATGTT GCTGCCGTGC ATGCTGCTGT TGCTGCTGAC CGCCGCTGCC 
GTTGCTGTCG GCGGCACGCG ACTGCCGCTC GAGGTGTTCG AGATTACGCC GACCACATCC 
ACAGCGGACA AGCACAAGAG TCTGCAGTAC ACCGTCGTCT ACGATGCCAA AGATATTTCA 
GGAGCAGCGG CAGCAACTGG AGTGGCGAGC AGTACAGTGA AGCCCGCCAC CGAGCAACTG 
ACCGTTGTGA GCATTTCCTC CACAGCGGCT GCGGAGAAGG ATCTCGCCGA GTCGCGGCGA 
CATGCGCGAC AAATGTTGCA GAAACAACAG CAGCATCGCA GCATCATCGG CGGCAAGCAC 
GGCGATCGGG ATGTGCGCAT CCTCTACCAA GTGGGGGACT CTGAGGAGGA TTTGCCCGTC 
TGTGCACCGA ATGCAGTTTG TTCCAAGATC GATCTATACG AAACCCCATG GATCGAGCGA 
CAATGTCGTT GTCCTGAATC GAATCGCATG CCCAACAATG TGATCATCCA TCATCACAGT 
CATTCCTCGG GATCGGTGGA TTCCCTGAAG TACAGGAACT ACTACGAAAG GGAGAAGATG 
ATGCAGCACA AGCGAATGCT GTTGGGTGAA TTTCAGGATA AGAAATTCGA AAGTCTGCAT 
ATGAAGAAGC TGATGCAGAA ACTGGGCGCC GTCTACGAGG ATGATTTGGA TCATCTGGAC 
CAGTCGCCGG ACTATAATGA CGCCCTGCCC TATGCGGAGG TGCAGGACAA TGAGTTTCCC 
AGGGGATCGG CGCACATGAG GCATTCCGGG CACCGAGGAT CCAAAGAGCC TGCAACCACA 
TTCATTGGCG GCTGTCCCAG CAGTTTGGGC GTTGAAGATG GCCACACCAT TGCCGATAAG 
ACTAGGCATT ACAAAATGTG CCAGCCGGTG CATAAGTTGC CAGTTTGCAC ACACTTCCGT 
GACTACACTT GGACTTTGAC AACAGCAGCC GAGTTGAATG TGACGGAGCA GATAGTCCAT 
TGTCGGTGTC CCCGGAATTC GGTGACATAC TTGACCAAGA GGGAACCCAT TGGCAATGGC 
AGTCCAGGCT ACAGATATCT GTTTGCCTGC TCTCCCCTGA CGCGTCTTCG CTGTCAGCGA 
AAGCAACCGT GCAAATTGTT CACGGTGCGA AAGCGCCAGG AGTTCCTGGA CGAGGTCAAC 
ATTAACTCGT TGTGCCAGTG CCCCAAAGGA CACCGCTGTC CCAGTCATCA CACGCAATCC 
GGCGTGATAG CCGGCGAGAG TTTTCTGGAG GACAACATAC AGACATATTC CGGTTACTGC 
ATGGCCAACG ATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_524107.2
CDS	575..1909
Translation	MPTTLMLLPCMLLLLLTAAAVAVGGTRLPLEVFEITPTTSTADKHKSLQYTVVYDAKDISGAAAATGVASSTVKPATEQLTVVSISSTAAAEKDLAESRRHARQMLQKQQQHRSIIGGKHGDRDVRILYQVGDSEEDLPVCAPNAVCSKIDLYETPWIERQCRCPESNRMPNNVIIHHHSHSSGSVDSLKYRNYYEREKMMQHKRMLLGEFQDKKFESLHMKKLMQKLGAVYEDDLDHLDQSPDYNDALPYAEVQDNEFPRGSAHMRHSGHRGSKEPATTFIGGCPSSLGVEDGHTIADKTRHYKMCQPVHKLPVCTHFRDYTWTLTTAAELNVTEQIVHCRCPRNSVTYLTKREPIGNGSPGYRYLFACSPLTRLRCQRKQPCKLFTVRKRQEFLDEVNINSLCQCPKGHRCPSHHTQSGVIAGESFLEDNIQTYSGYCMAND

Target ORF information:

RefSeq Version	NM_079383.3
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster argos (aos), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_079383.3

ORF Insert Sequence:

ATGCCTACGA CATTGATGTT GCTGCCGTGC ATGCTGCTGT TGCTGCTGAC CGCCGCTGCC 
GTTGCTGTCG GCGGCACGCG ACTGCCGCTC GAGGTGTTCG AGATTACGCC GACCACATCC 
ACAGCGGACA AGCACAAGAG TCTGCAGTAC ACCGTCGTCT ACGATGCCAA AGATATTTCA 
GGAGCAGCGG CAGCAACTGG AGTGGCGAGC AGTACAGTGA AGCCCGCCAC CGAGCAACTG 
ACCGTTGTGA GCATTTCCTC CACAGCGGCT GCGGAGAAGG ATCTCGCCGA GTCGCGGCGA 
CATGCGCGAC AAATGTTGCA GAAACAACAG CAGCATCGCA GCATCATCGG CGGCAAGCAC 
GGCGATCGGG ATGTGCGCAT CCTCTACCAA GTGGGGGACT CTGAGGAGGA TTTGCCCGTC 
TGTGCACCGA ATGCAGTTTG TTCCAAGATC GATCTATACG AAACCCCATG GATCGAGCGA 
CAATGTCGTT GTCCTGAATC GAATCGCATG CCCAACAATG TGATCATCCA TCATCACAGT 
CATTCCTCGG GATCGGTGGA TTCCCTGAAG TACAGGAACT ACTACGAAAG GGAGAAGATG 
ATGCAGCACA AGCGAATGCT GTTGGGTGAA TTTCAGGATA AGAAATTCGA AAGTCTGCAT 
ATGAAGAAGC TGATGCAGAA ACTGGGCGCC GTCTACGAGG ATGATTTGGA TCATCTGGAC 
CAGTCGCCGG ACTATAATGA CGCCCTGCCC TATGCGGAGG TGCAGGACAA TGAGTTTCCC 
AGGGGATCGG CGCACATGAG GCATTCCGGG CACCGAGGAT CCAAAGAGCC TGCAACCACA 
TTCATTGGCG GCTGTCCCAG CAGTTTGGGC GTTGAAGATG GCCACACCAT TGCCGATAAG 
ACTAGGCATT ACAAAATGTG CCAGCCGGTG CATAAGTTGC CAGTTTGCAC ACACTTCCGT 
GACTACACTT GGACTTTGAC AACAGCAGCC GAGTTGAATG TGACGGAGCA GATAGTCCAT 
TGTCGGTGTC CCCGGAATTC GGTGACATAC TTGACCAAGA GGGAACCCAT TGGCAATGGC 
AGTCCAGGCT ACAGATATCT GTTTGCCTGC TCTCCCCTGA CGCGTCTTCG CTGTCAGCGA 
AAGCAACCGT GCAAATTGTT CACGGTGCGA AAGCGCCAGG AGTTCCTGGA CGAGGTCAAC 
ATTAACTCGT TGTGCCAGTG CCCCAAAGGA CACCGCTGTC CCAGTCATCA CACGCAATCC 
GGCGTGATAG CCGGCGAGAG TTTTCTGGAG GACAACATAC AGACATATTC CGGTTACTGC 
ATGGCCAACG ATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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aos cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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