Mul1 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mul1
Entrez Gene ID	38472
Full Name	Mitochondrial E3 ubiquitin protein ligase 1
Synonyms	CG1134,Dmel\CG1134,MUL1
General protein information	Preferred Names Mitochondrial E3 ubiquitin protein ligase 1 Names CG1134 gene product from transcript CG1134-RB CG1134-PA CG1134-PB Mul1-PA Mul1-PB mitochondrial E3 ubiquitin protein ligase 1 mitochondrial E3 ubiquitin protein ligase 1 homologue
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 3L Map Location: 64A4-64A4

mRNA and Protein(s)

mRNA	Protein	Name
NM_139590.4	NP_647847.1	mitochondrial E3 ubiquitin protein ligase 1, isoform A
NM_001316436.1	NP_001303365.1	mitochondrial E3 ubiquitin protein ligase 1, isoform B

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP005955	XP_315995.1
Drosophila melanogaster (fruit fly)	Mul1	NP_647847.1
Gallus gallus (chicken)	LOC770265	XP_003641813.1
Danio rerio (zebrafish)	mul1a	NP_001018134.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

MUL1 acts in parallel to the PINK1/parkin pathway on a shared target mitofusin to maintain mitochondrial integrity.
Title: MUL1 acts in parallel to the PINK1/parkin pathway in regulating mitofusin and compensates for loss of PINK1/parkin.

The following Mul1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mul1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa17445	NM_001316436.1 Latest version!	Drosophila melanogaster mitochondrial E3 ubiquitin protein ligase 1, transcript variant B (Mul1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00
OFa17445	NM_139590.4 Latest version!	Drosophila melanogaster mitochondrial E3 ubiquitin protein ligase 1, transcript variant A (Mul1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mul1 ( NM_139590.4 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_647847.1 Drosophila melanogaster mitochondrial E3 ubiquitin protein ligase 1, transcript variant A (Mul1), mRNA.

Price & Availability↑

CloneID	OFa17445
Clone ID Related Accession (Same CDS sequence)	NM_139590.4 , NM_001316436.1
Accession Version	NM_139590.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1017bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	mitochondrial E3 ubiquitin protein ligase 1, isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_037436). On Jan 16, 2013 this sequence version replaced NM_139590.3. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGAATTTT TACACGAATC CGTTGCACTG GGCGTGGATC TGCTAATACT TGGCCTGTGT 
GCGCGCGAGT ACGTGCACTA CAAGCGAACT GCCAAGGTGC TGAAGGCGGC ACCACAATAC 
AACATCGATG GAGACCTAAA ATCGGTGGTG GAGCGGCAGC GCGACAAGAA GATACCATAT 
GCGGTAATCC GGGGCACAGT GACGCCCATC GGGGTGCCAC TGAGGAGCTC CCTGGTGCCC 
AGTGTGAGTG GAGTGCTGCA GATTGTGAAG CTGCATGAGC ACAGGGTAAC GCGCGGATTC 
GCCGGCTTCT GGACGGAACA ACACAAGTTG CTGCACGAAT CCGCCAACGA GATGCCCTTC 
GAGTTGCGTA ACCAGAGCCA TGGTGTGGAG ATTGTGGACG CCTTGAGTGC CGCCGTCTTG 
GACGTGGACG TGGTCTACGA CAACTACGAG CCCTCCAATC TGTCCCTCTT CGACCATGTG 
TTTGGTTTCT TCTCTGGCGT CCGTCAGAGG GGATTGCAAA CGACGGAGGA GGTGCTCAGA 
GAAGGCAGCT TCCTGACCGC TATTGGTGAA CTGGAGTTGG ATGGCGATAC TCTGCGCATG 
CAGCCCTCCA ATGAGGGACC GCTCTTCCTG ACCACTGCCA CCAAGTCCAC GCTTATTAAG 
CGGTTCGAAG ATGCCAAGAC AACGACGATA CTCAAGCTGG TTGTGTGCAG CACCATCTCT 
GCCATCCTGG TTGCCTTCAT TGCCAAGAAA CTCTACCGAA AACGAAAGCA GGAGCGGGAG 
GAGGCCAAAA TTCGCGAACG CCTGGATACG GAGCGTCGGG AGCGGAGGGC GAGGAGTCGT 
CCTCACACTC TGTCCCAGGA TCAACTCTGC GTGGTGTGCT CCACCAATCC CAAGGAGATT 
ATCCTACTGC CATGTGGTCA TGTGTGTCTC TGCGAGGACT GTGCCCAGAA AATCTCCGTC 
ACCTGCCCCG TGTGTCGTGG TAGCATCGTC TCCAAGGCAG CCGCCTTCAT CGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_647847.1
CDS	79..1095
Translation	MEFLHESVALGVDLLILGLCAREYVHYKRTAKVLKAAPQYNIDGDLKSVVERQRDKKIPYAVIRGTVTPIGVPLRSSLVPSVSGVLQIVKLHEHRVTRGFAGFWTEQHKLLHESANEMPFELRNQSHGVEIVDALSAAVLDVDVVYDNYEPSNLSLFDHVFGFFSGVRQRGLQTTEEVLREGSFLTAIGELELDGDTLRMQPSNEGPLFLTTATKSTLIKRFEDAKTTTILKLVVCSTISAILVAFIAKKLYRKRKQEREEAKIRERLDTERRERRARSRPHTLSQDQLCVVCSTNPKEIILLPCGHVCLCEDCAQKISVTCPVCRGSIVSKAAAFIA

Target ORF information:

RefSeq Version	NM_139590.4
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster mitochondrial E3 ubiquitin protein ligase 1, transcript variant A (Mul1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139590.4

ORF Insert Sequence:

ATGGAATTTT TACACGAATC CGTTGCACTG GGCGTGGATC TGCTAATACT TGGCCTGTGT 
GCGCGCGAGT ACGTGCACTA CAAGCGAACT GCCAAGGTGC TGAAGGCGGC ACCACAATAC 
AACATCGATG GAGACCTAAA ATCGGTGGTG GAGCGGCAGC GCGACAAGAA GATACCATAT 
GCGGTAATCC GGGGCACAGT GACGCCCATC GGGGTGCCAC TGAGGAGCTC CCTGGTGCCC 
AGTGTGAGTG GAGTGCTGCA GATTGTGAAG CTGCATGAGC ACAGGGTAAC GCGCGGATTC 
GCCGGCTTCT GGACGGAACA ACACAAGTTG CTGCACGAAT CCGCCAACGA GATGCCCTTC 
GAGTTGCGTA ACCAGAGCCA TGGTGTGGAG ATTGTGGACG CCTTGAGTGC CGCCGTCTTG 
GACGTGGACG TGGTCTACGA CAACTACGAG CCCTCCAATC TGTCCCTCTT CGACCATGTG 
TTTGGTTTCT TCTCTGGCGT CCGTCAGAGG GGATTGCAAA CGACGGAGGA GGTGCTCAGA 
GAAGGCAGCT TCCTGACCGC TATTGGTGAA CTGGAGTTGG ATGGCGATAC TCTGCGCATG 
CAGCCCTCCA ATGAGGGACC GCTCTTCCTG ACCACTGCCA CCAAGTCCAC GCTTATTAAG 
CGGTTCGAAG ATGCCAAGAC AACGACGATA CTCAAGCTGG TTGTGTGCAG CACCATCTCT 
GCCATCCTGG TTGCCTTCAT TGCCAAGAAA CTCTACCGAA AACGAAAGCA GGAGCGGGAG 
GAGGCCAAAA TTCGCGAACG CCTGGATACG GAGCGTCGGG AGCGGAGGGC GAGGAGTCGT 
CCTCACACTC TGTCCCAGGA TCAACTCTGC GTGGTGTGCT CCACCAATCC CAAGGAGATT 
ATCCTACTGC CATGTGGTCA TGTGTGTCTC TGCGAGGACT GTGCCCAGAA AATCTCCGTC 
ACCTGCCCCG TGTGTCGTGG TAGCATCGTC TCCAAGGCAG CCGCCTTCAT CGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mul1 ( NM_001316436.1 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_001303365.1 Drosophila melanogaster mitochondrial E3 ubiquitin protein ligase 1, transcript variant B (Mul1), mRNA.

Price & Availability↑

CloneID	OFa17445
Clone ID Related Accession (Same CDS sequence)	NM_139590.4 , NM_001316436.1
Accession Version	NM_001316436.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1017bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	mitochondrial E3 ubiquitin protein ligase 1, isoform B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_037436). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGAATTTT TACACGAATC CGTTGCACTG GGCGTGGATC TGCTAATACT TGGCCTGTGT 
GCGCGCGAGT ACGTGCACTA CAAGCGAACT GCCAAGGTGC TGAAGGCGGC ACCACAATAC 
AACATCGATG GAGACCTAAA ATCGGTGGTG GAGCGGCAGC GCGACAAGAA GATACCATAT 
GCGGTAATCC GGGGCACAGT GACGCCCATC GGGGTGCCAC TGAGGAGCTC CCTGGTGCCC 
AGTGTGAGTG GAGTGCTGCA GATTGTGAAG CTGCATGAGC ACAGGGTAAC GCGCGGATTC 
GCCGGCTTCT GGACGGAACA ACACAAGTTG CTGCACGAAT CCGCCAACGA GATGCCCTTC 
GAGTTGCGTA ACCAGAGCCA TGGTGTGGAG ATTGTGGACG CCTTGAGTGC CGCCGTCTTG 
GACGTGGACG TGGTCTACGA CAACTACGAG CCCTCCAATC TGTCCCTCTT CGACCATGTG 
TTTGGTTTCT TCTCTGGCGT CCGTCAGAGG GGATTGCAAA CGACGGAGGA GGTGCTCAGA 
GAAGGCAGCT TCCTGACCGC TATTGGTGAA CTGGAGTTGG ATGGCGATAC TCTGCGCATG 
CAGCCCTCCA ATGAGGGACC GCTCTTCCTG ACCACTGCCA CCAAGTCCAC GCTTATTAAG 
CGGTTCGAAG ATGCCAAGAC AACGACGATA CTCAAGCTGG TTGTGTGCAG CACCATCTCT 
GCCATCCTGG TTGCCTTCAT TGCCAAGAAA CTCTACCGAA AACGAAAGCA GGAGCGGGAG 
GAGGCCAAAA TTCGCGAACG CCTGGATACG GAGCGTCGGG AGCGGAGGGC GAGGAGTCGT 
CCTCACACTC TGTCCCAGGA TCAACTCTGC GTGGTGTGCT CCACCAATCC CAAGGAGATT 
ATCCTACTGC CATGTGGTCA TGTGTGTCTC TGCGAGGACT GTGCCCAGAA AATCTCCGTC 
ACCTGCCCCG TGTGTCGTGG TAGCATCGTC TCCAAGGCAG CCGCCTTCAT CGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001303365.1
CDS	79..1095
Translation	MEFLHESVALGVDLLILGLCAREYVHYKRTAKVLKAAPQYNIDGDLKSVVERQRDKKIPYAVIRGTVTPIGVPLRSSLVPSVSGVLQIVKLHEHRVTRGFAGFWTEQHKLLHESANEMPFELRNQSHGVEIVDALSAAVLDVDVVYDNYEPSNLSLFDHVFGFFSGVRQRGLQTTEEVLREGSFLTAIGELELDGDTLRMQPSNEGPLFLTTATKSTLIKRFEDAKTTTILKLVVCSTISAILVAFIAKKLYRKRKQEREEAKIRERLDTERRERRARSRPHTLSQDQLCVVCSTNPKEIILLPCGHVCLCEDCAQKISVTCPVCRGSIVSKAAAFIA

Target ORF information:

RefSeq Version	NM_001316436.1
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster mitochondrial E3 ubiquitin protein ligase 1, transcript variant B (Mul1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001316436.1

ORF Insert Sequence:

ATGGAATTTT TACACGAATC CGTTGCACTG GGCGTGGATC TGCTAATACT TGGCCTGTGT 
GCGCGCGAGT ACGTGCACTA CAAGCGAACT GCCAAGGTGC TGAAGGCGGC ACCACAATAC 
AACATCGATG GAGACCTAAA ATCGGTGGTG GAGCGGCAGC GCGACAAGAA GATACCATAT 
GCGGTAATCC GGGGCACAGT GACGCCCATC GGGGTGCCAC TGAGGAGCTC CCTGGTGCCC 
AGTGTGAGTG GAGTGCTGCA GATTGTGAAG CTGCATGAGC ACAGGGTAAC GCGCGGATTC 
GCCGGCTTCT GGACGGAACA ACACAAGTTG CTGCACGAAT CCGCCAACGA GATGCCCTTC 
GAGTTGCGTA ACCAGAGCCA TGGTGTGGAG ATTGTGGACG CCTTGAGTGC CGCCGTCTTG 
GACGTGGACG TGGTCTACGA CAACTACGAG CCCTCCAATC TGTCCCTCTT CGACCATGTG 
TTTGGTTTCT TCTCTGGCGT CCGTCAGAGG GGATTGCAAA CGACGGAGGA GGTGCTCAGA 
GAAGGCAGCT TCCTGACCGC TATTGGTGAA CTGGAGTTGG ATGGCGATAC TCTGCGCATG 
CAGCCCTCCA ATGAGGGACC GCTCTTCCTG ACCACTGCCA CCAAGTCCAC GCTTATTAAG 
CGGTTCGAAG ATGCCAAGAC AACGACGATA CTCAAGCTGG TTGTGTGCAG CACCATCTCT 
GCCATCCTGG TTGCCTTCAT TGCCAAGAAA CTCTACCGAA AACGAAAGCA GGAGCGGGAG 
GAGGCCAAAA TTCGCGAACG CCTGGATACG GAGCGTCGGG AGCGGAGGGC GAGGAGTCGT 
CCTCACACTC TGTCCCAGGA TCAACTCTGC GTGGTGTGCT CCACCAATCC CAAGGAGATT 
ATCCTACTGC CATGTGGTCA TGTGTGTCTC TGCGAGGACT GTGCCCAGAA AATCTCCGTC 
ACCTGCCCCG TGTGTCGTGG TAGCATCGTC TCCAAGGCAG CCGCCTTCAT CGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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Mul1 cDNA ORF clone, Drosophila melanogaster(fruit fly)

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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