PHGPx cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	PHGPx
Entrez Gene ID	38413
Full Name	CG12013 gene product from transcript CG12013-RC
Synonyms	CG12013,DmGPx,DmPHGPx,Dmel\CG12013,GPx,GTPx,GTPx-1,Gtpx-1,PGTPx,anon-WO0257455.17,phGpx
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 3L Map Location: 63D1-63D1

mRNA and Protein(s)

mRNA	Protein	Name
NM_168024.2	NP_728868.1	PHGPx, isoform C
NM_168026.2	NP_728870.1	PHGPx, isoform A
NM_168025.2	NP_728869.1	PHGPx, isoform D

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	GPX4	NP_001139295.1
Caenorhabditis elegans (roundworm)	F26E4.12	NP_492598.1
Arabidopsis thaliana (thale cress)	GPX6	NP_192897.2
Oryza sativa (rice)	Os02g0664000	NP_001047659.1
Danio rerio (zebrafish)	gpx4a	NP_001007283.2
Drosophila melanogaster (fruit fly)	PHGPx	NP_728869.1
Anopheles gambiae (African malaria mosquito)	GPXH1	XP_003436755.1
Caenorhabditis elegans (roundworm)	R05H10.5	NP_497078.1
Oryza sativa (rice)	Os04g0556300	NP_001053524.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

e catalytic mechanism of DmGPx, unlike that of selenocysteine (Sec)GPxs, involves formation of an internal disulfide that is pivotal to the interaction with Trx
Title: The thioredoxin specificity of Drosophila GPx: a paradigm for a peroxiredoxin-like mechanism of many glutathione peroxidases.

The following PHGPx gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PHGPx cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OFa17375	NM_168024.2 Latest version!	Drosophila melanogaster PHGPx, transcript variant C (PHGPx), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OFa17376	NM_168025.2 Latest version!	Drosophila melanogaster PHGPx, transcript variant D (PHGPx), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
OFa17377	NM_168026.2 Latest version!	Drosophila melanogaster PHGPx, transcript variant A (PHGPx), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PHGPx ( NM_168024.2 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_728868.1 Drosophila melanogaster PHGPx, transcript variant C (PHGPx), mRNA.

Price & Availability↑

CloneID	OFa17375
Clone ID Related Accession (Same CDS sequence)	NM_168024.2
Accession Version	NM_168024.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 597bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	PHGPx, isoform C
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_037436). On Jan 16, 2013 this sequence version replaced NM_168024.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGCTGGCC GCTCCATCGT CCACTTTTTT CTGGGGTCCG TGGCAATCGC CCTGGGATCG 
TACATCTACT TCACCATGCA AATCGACATG TCTGCTAACG GAGATTACAA GAACGCCGCC 
TCGATCTACG AGTTCACCGT GAAGGATACC CATGGCAACG ATGTTTCCCT GGAAAAGTAC 
AAGGGCAAGG TGGTCCTGGT GGTGAACATC GCCTCCAAGT GCGGCCTGAC CAAGAACAAC 
TACGAGAAGC TGACGGATCT AAAGGAGAAG TACGGCGAGC GCGGCCTGGT GATCCTCAAC 
TTCCCGTGCA ATCAGTTTGG GTCCCAGATG CCGGAGGCCG ATGGAGAGGC CATGGTGTGC 
CACCTGCGCG ACTCCAAGGC TGACATCGGC GAGGTGTTCG CCAAGGTCGA TGTGAATGGA 
GACAATGCGG CGCCGCTGTA CAAATACCTA AAGGCCAAGC AGACCGGCAC CCTGGGCAGC 
GGAATCAAGT GGAACTTCAC CAAGTTTCTG GTGAACAAGG AGGGCGTGCC CATCAACCGA 
TATGCCCCGA CCACCGATCC CATGGACATC GCCAAGGACA TTGAAAAGCT GCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_728868.1
CDS	368..964
Translation	MAGRSIVHFFLGSVAIALGSYIYFTMQIDMSANGDYKNAASIYEFTVKDTHGNDVSLEKYKGKVVLVVNIASKCGLTKNNYEKLTDLKEKYGERGLVILNFPCNQFGSQMPEADGEAMVCHLRDSKADIGEVFAKVDVNGDNAAPLYKYLKAKQTGTLGSGIKWNFTKFLVNKEGVPINRYAPTTDPMDIAKDIEKLL

Target ORF information:

RefSeq Version	NM_168024.2
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster PHGPx, transcript variant C (PHGPx), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_168024.2

ORF Insert Sequence:

ATGGCTGGCC GCTCCATCGT CCACTTTTTT CTGGGGTCCG TGGCAATCGC CCTGGGATCG 
TACATCTACT TCACCATGCA AATCGACATG TCTGCTAACG GAGATTACAA GAACGCCGCC 
TCGATCTACG AGTTCACCGT GAAGGATACC CATGGCAACG ATGTTTCCCT GGAAAAGTAC 
AAGGGCAAGG TGGTCCTGGT GGTGAACATC GCCTCCAAGT GCGGCCTGAC CAAGAACAAC 
TACGAGAAGC TGACGGATCT AAAGGAGAAG TACGGCGAGC GCGGCCTGGT GATCCTCAAC 
TTCCCGTGCA ATCAGTTTGG GTCCCAGATG CCGGAGGCCG ATGGAGAGGC CATGGTGTGC 
CACCTGCGCG ACTCCAAGGC TGACATCGGC GAGGTGTTCG CCAAGGTCGA TGTGAATGGA 
GACAATGCGG CGCCGCTGTA CAAATACCTA AAGGCCAAGC AGACCGGCAC CCTGGGCAGC 
GGAATCAAGT GGAACTTCAC CAAGTTTCTG GTGAACAAGG AGGGCGTGCC CATCAACCGA 
TATGCCCCGA CCACCGATCC CATGGACATC GCCAAGGACA TTGAAAAGCT GCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PHGPx ( NM_168025.2 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_728869.1 Drosophila melanogaster PHGPx, transcript variant D (PHGPx), mRNA.

Price & Availability↑

CloneID	OFa17376
Clone ID Related Accession (Same CDS sequence)	NM_168025.2
Accession Version	NM_168025.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 717bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	PHGPx, isoform D
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_037436). On Jan 16, 2013 this sequence version replaced NM_168025.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGAGTCTCA GGCAGTTTCA GAACATTTCC CGCCAGGCCC TCAGGTGCTA CTCGATGAGG 
CGGACCCCTG GCCCCGTCCT CGAGCTGAGT CGCGGTCAGA GGCAGTGCCT TCGCCTCTGC 
ACCATCATGC TTCCCGTGAG CTGTGCGGCC ACGCCCATGA ACGCCATCTC CTCAGCCGCC 
CAGCACTCCA CAGCAGCTGC CATCGACATG TCTGCTAACG GAGATTACAA GAACGCCGCC 
TCGATCTACG AGTTCACCGT GAAGGATACC CATGGCAACG ATGTTTCCCT GGAAAAGTAC 
AAGGGCAAGG TGGTCCTGGT GGTGAACATC GCCTCCAAGT GCGGCCTGAC CAAGAACAAC 
TACGAGAAGC TGACGGATCT AAAGGAGAAG TACGGCGAGC GCGGCCTGGT GATCCTCAAC 
TTCCCGTGCA ATCAGTTTGG GTCCCAGATG CCGGAGGCCG ATGGAGAGGC CATGGTGTGC 
CACCTGCGCG ACTCCAAGGC TGACATCGGC GAGGTGTTCG CCAAGGTCGA TGTGAATGGA 
GACAATGCGG CGCCGCTGTA CAAATACCTA AAGGCCAAGC AGACCGGCAC CCTGGGCAGC 
GGAATCAAGT GGAACTTCAC CAAGTTTCTG GTGAACAAGG AGGGCGTGCC CATCAACCGA 
TATGCCCCGA CCACCGATCC CATGGACATC GCCAAGGACA TTGAAAAGCT GCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_728869.1
CDS	114..830
Translation	MSLRQFQNISRQALRCYSMRRTPGPVLELSRGQRQCLRLCTIMLPVSCAATPMNAISSAAQHSTAAAIDMSANGDYKNAASIYEFTVKDTHGNDVSLEKYKGKVVLVVNIASKCGLTKNNYEKLTDLKEKYGERGLVILNFPCNQFGSQMPEADGEAMVCHLRDSKADIGEVFAKVDVNGDNAAPLYKYLKAKQTGTLGSGIKWNFTKFLVNKEGVPINRYAPTTDPMDIAKDIEKLL

Target ORF information:

RefSeq Version	NM_168025.2
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster PHGPx, transcript variant D (PHGPx), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_168025.2

ORF Insert Sequence:

ATGAGTCTCA GGCAGTTTCA GAACATTTCC CGCCAGGCCC TCAGGTGCTA CTCGATGAGG 
CGGACCCCTG GCCCCGTCCT CGAGCTGAGT CGCGGTCAGA GGCAGTGCCT TCGCCTCTGC 
ACCATCATGC TTCCCGTGAG CTGTGCGGCC ACGCCCATGA ACGCCATCTC CTCAGCCGCC 
CAGCACTCCA CAGCAGCTGC CATCGACATG TCTGCTAACG GAGATTACAA GAACGCCGCC 
TCGATCTACG AGTTCACCGT GAAGGATACC CATGGCAACG ATGTTTCCCT GGAAAAGTAC 
AAGGGCAAGG TGGTCCTGGT GGTGAACATC GCCTCCAAGT GCGGCCTGAC CAAGAACAAC 
TACGAGAAGC TGACGGATCT AAAGGAGAAG TACGGCGAGC GCGGCCTGGT GATCCTCAAC 
TTCCCGTGCA ATCAGTTTGG GTCCCAGATG CCGGAGGCCG ATGGAGAGGC CATGGTGTGC 
CACCTGCGCG ACTCCAAGGC TGACATCGGC GAGGTGTTCG CCAAGGTCGA TGTGAATGGA 
GACAATGCGG CGCCGCTGTA CAAATACCTA AAGGCCAAGC AGACCGGCAC CCTGGGCAGC 
GGAATCAAGT GGAACTTCAC CAAGTTTCTG GTGAACAAGG AGGGCGTGCC CATCAACCGA 
TATGCCCCGA CCACCGATCC CATGGACATC GCCAAGGACA TTGAAAAGCT GCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PHGPx ( NM_168026.2 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_728870.1 Drosophila melanogaster PHGPx, transcript variant A (PHGPx), mRNA.

Price & Availability↑

CloneID	OFa17377
Clone ID Related Accession (Same CDS sequence)	NM_168026.2
Accession Version	NM_168026.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 510bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	PHGPx, isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_037436). On Jan 16, 2013 this sequence version replaced NM_168026.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGTCTGCTA ACGGAGATTA CAAGAACGCC GCCTCGATCT ACGAGTTCAC CGTGAAGGAT 
ACCCATGGCA ACGATGTTTC CCTGGAAAAG TACAAGGGCA AGGTGGTCCT GGTGGTGAAC 
ATCGCCTCCA AGTGCGGCCT GACCAAGAAC AACTACGAGA AGCTGACGGA TCTAAAGGAG 
AAGTACGGCG AGCGCGGCCT GGTGATCCTC AACTTCCCGT GCAATCAGTT TGGGTCCCAG 
ATGCCGGAGG CCGATGGAGA GGCCATGGTG TGCCACCTGC GCGACTCCAA GGCTGACATC 
GGCGAGGTGT TCGCCAAGGT CGATGTGAAT GGAGACAATG CGGCGCCGCT GTACAAATAC 
CTAAAGGCCA AGCAGACCGG CACCCTGGGC AGCGGAATCA AGTGGAACTT CACCAAGTTT 
CTGGTGAACA AGGAGGGCGT GCCCATCAAC CGATATGCCC CGACCACCGA TCCCATGGAC 
ATCGCCAAGG ACATTGAAAA GCTGCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_728870.1
CDS	110..619
Translation	MSANGDYKNAASIYEFTVKDTHGNDVSLEKYKGKVVLVVNIASKCGLTKNNYEKLTDLKEKYGERGLVILNFPCNQFGSQMPEADGEAMVCHLRDSKADIGEVFAKVDVNGDNAAPLYKYLKAKQTGTLGSGIKWNFTKFLVNKEGVPINRYAPTTDPMDIAKDIEKLL

Target ORF information:

RefSeq Version	NM_168026.2
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster PHGPx, transcript variant A (PHGPx), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_168026.2

ORF Insert Sequence:

ATGTCTGCTA ACGGAGATTA CAAGAACGCC GCCTCGATCT ACGAGTTCAC CGTGAAGGAT 
ACCCATGGCA ACGATGTTTC CCTGGAAAAG TACAAGGGCA AGGTGGTCCT GGTGGTGAAC 
ATCGCCTCCA AGTGCGGCCT GACCAAGAAC AACTACGAGA AGCTGACGGA TCTAAAGGAG 
AAGTACGGCG AGCGCGGCCT GGTGATCCTC AACTTCCCGT GCAATCAGTT TGGGTCCCAG 
ATGCCGGAGG CCGATGGAGA GGCCATGGTG TGCCACCTGC GCGACTCCAA GGCTGACATC 
GGCGAGGTGT TCGCCAAGGT CGATGTGAAT GGAGACAATG CGGCGCCGCT GTACAAATAC 
CTAAAGGCCA AGCAGACCGG CACCCTGGGC AGCGGAATCA AGTGGAACTT CACCAAGTTT 
CTGGTGAACA AGGAGGGCGT GCCCATCAAC CGATATGCCC CGACCACCGA TCCCATGGAC 
ATCGCCAAGG ACATTGAAAA GCTGCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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PHGPx cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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