Klp59C cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	Klp59C
Entrez Gene ID	37671
Full Name	Kinesin-like protein at 59C
Synonyms	CG3219,DmCG3219,DmKLP59C,DmKlp59C,Dmel\CG3219,KIF 2B,KIF2A/B/C,KLP59C
General protein information	Preferred Names Kinesin-like protein at 59C Names CG3219 gene product from transcript CG3219-RA CG3219-PA Kinesin13C Klp59C-PA kinesin-13
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 2R Map Location: 59C4-59C4

mRNA and Protein(s)

mRNA	Protein	Name
NM_137915.4	NP_611759.1	Kinesin-like protein at 59C

Pathways from BioSystems

Homologies

Drosophila melanogaster (fruit fly)	Klp59C	NP_611759.1
Drosophila melanogaster (fruit fly)	Klp59D	NP_611762.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This review reveals remarkable coordination between two kinesin 13 family members, KLP59C and KLP10A, in which KLP10A initiates microtubule depolymerization while KLP59C perpetuates depolymerization after its initiation.
Title: KLP10A and KLP59C: the dynamic duo of microtubule depolymerization.

two functionally distinct microtubule-destabilizing KinI kinesin enzymes are responsible for normal chromatid-to-pole motion in Drosophila
Title: Two mitotic kinesins cooperate to drive sister chromatid separation during anaphase.

The following Klp59C gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Klp59C cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa10996	NM_137915.4 Latest version!	Drosophila melanogaster Kinesin-like protein at 59C (Klp59C), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Klp59C ( NM_137915.4 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_611759.1 Drosophila melanogaster Kinesin-like protein at 59C (Klp59C), mRNA.

Price & Availability↑

CloneID	OFa10996
Clone ID Related Accession (Same CDS sequence)	NM_137915.4
Accession Version	NM_137915.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1881bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	Kinesin-like protein at 59C
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033778). On Jul 15, 2014 this sequence version replaced NM_137915.3. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGATAAGT TGTCGATCGA ACAGAAGATT TTCATCCGTC GCTCGGACGG TAGAGTCCAC 
TTGGCGGAGA TTATCAAACT GGAGGGCGGT GACTCCAAGC TGATTACGGT GGAGTGGCCC 
GAAGGACATA CGGTGCGTGG TAAGGAACTG CCCCTGGAGC TGGTGGTCCT GATGAATCCT 
CATATCTTCG ACTCGCCCCG CTGCAGTGGC GGCAATGCGG CGTCAGCCAA TCAAACTGCC 
TCCATATCGC CACGTTCAAT GAAACAACGA ATAGCGACTG GGAGCTTATC TCCTGTACTG 
GCCACTGCCC CGCCACGCCA GCAGACGGCG CCGCCAGTTC GAGAGGACGA GGTGGTGCAC 
CAGGCTGAAA GAATGCGAAA AGAACGGGAA CGGAGGCGAG AAGCACAAGC CAGGACTCGT 
CTAGATCGGG AGCAGGGGAA GAACGAAGAT CCGGGAAATC CCAACTGGGA AGTAGCCAGA 
ATGATACGAC TGCAACGCGA GCAAATGGAG AGTCAGCGGG TGAGAAGTGG TACTACGAAC 
GAACGAATCA ATTGCCACCA AATTATGGTT TGTGTGAGGA AGAGACCACT GAGGCGCAAG 
GAGCTGGCTG ACCGGGAACA GGATGTGGTC AGCATTCCGT CTAAGCACAC ATTGGTGGTC 
CACGAGCCCC GCAAGCATGT GAACCTGGTC AAGTTCCTGG AAAATCATAG CTTCCGTTTC 
GATTACGTCT TCGACGAGGA GTGCTCCAAT GCCACGGTCT ACGAATTCAC AGCCCGACCC 
TTGATAAAGC ACATTTTTGA TGGCGGAATG GCCACGTGTT TCGCCTACGG ACAAACTGGA 
AGCGGCAAGA CCTATACGAT GGGTGGTCAG TTCCCCGGAA GGCATCAGAG CTCAATGGAT 
GGCATCTATG CAATGGCCGC TAAGGACGTG TTCTCCACTC TAAAGACGGT TCCCTATAAC 
AAGCTTAATC TGAAAGTTTA CTGCAGCTTC TTCGAGATCT ACGGCACCCG GGTGTTCGAT 
CTCCTGATGC CTGGCAAGCC ACAACTGCGT GTCTTGGAGG ATAGAAACCA GCAGGTGCAA 
GTGGTGGGCC TCACCCAGAA TCCAGTACAG AACACCGCCG AAGTTCTGGA CCTACTCGAG 
TTGGGCAATA GTGTCCGAAC CTCGGGTCAC ACCTCTGCCA ATTCCAAGTC CTCCCGATCG 
CATGCTGTGT TCCAAATCGT GCTGAGATCC GCGGCGGGCG AGAAGCTACA CGGGAAATTC 
TCGCTTATAG ATCTGGCCGG GAATGAAAGA GGAGCGGACA ACAGCTCGGC GGATCGACAG 
ACGCGCCTGG AAGGATCCGA GATCAATAAA TCGCTGCTGG TCCTCAAGGA ATGCATTCGC 
GCTCTGGGGC GCCAGTCGAG TCATTTGCCA TTCCGTGGCT CCAAGCTGAC CCAAGTCCTG 
CGGGACTCCT TCATCGGAGG TAAGAAGGTG AAAACCTGCA TGATAGCCAT GATCTCGCCA 
TGCTTGCATT CGGTGGAGCA TACCTTGAAC ACGCTGCGTT ATGCGGATCG GGTGAAGGAA 
CTAAGTGTGG AGTCGATCCC ATCTAAACGG ATGCCCGATG CCAACCTTGG AAGCACTTCC 
ATGTCAGATA TTGTTTGCCA GTCGTCCACC CAGCGACTCT TTCCATGTGC CTCCTCCACA 
TCGATGCCAG GTGGTGGCAA CCAAGCGCAG CAACACACCA ACACCGCGAA CGACTTGAAC 
AGATCCCAGA AACCAACATC TAAGCCCACT TATCCCACAT CCGGTCAGCA GCTGGTCCAG 
AGGAAGGGAA GCTCCCAACG GGAGGCCTCC ATGATGCTGA CCAAATCCCT GGCACAATTC 
CGAGGGCGCA ACTTTCCCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_611759.1
CDS	136..2016
Translation	MDKLSIEQKIFIRRSDGRVHLAEIIKLEGGDSKLITVEWPEGHTVRGKELPLELVVLMNPHIFDSPRCSGGNAASANQTASISPRSMKQRIATGSLSPVLATAPPRQQTAPPVREDEVVHQAERMRKERERRREAQARTRLDREQGKNEDPGNPNWEVARMIRLQREQMESQRVRSGTTNERINCHQIMVCVRKRPLRRKELADREQDVVSIPSKHTLVVHEPRKHVNLVKFLENHSFRFDYVFDEECSNATVYEFTARPLIKHIFDGGMATCFAYGQTGSGKTYTMGGQFPGRHQSSMDGIYAMAAKDVFSTLKTVPYNKLNLKVYCSFFEIYGTRVFDLLMPGKPQLRVLEDRNQQVQVVGLTQNPVQNTAEVLDLLELGNSVRTSGHTSANSKSSRSHAVFQIVLRSAAGEKLHGKFSLIDLAGNERGADNSSADRQTRLEGSEINKSLLVLKECIRALGRQSSHLPFRGSKLTQVLRDSFIGGKKVKTCMIAMISPCLHSVEHTLNTLRYADRVKELSVESIPSKRMPDANLGSTSMSDIVCQSSTQRLFPCASSTSMPGGGNQAQQHTNTANDLNRSQKPTSKPTYPTSGQQLVQRKGSSQREASMMLTKSLAQFRGRNFP

Target ORF information:

RefSeq Version	NM_137915.4
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster Kinesin-like protein at 59C (Klp59C), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_137915.4

ORF Insert Sequence:

ATGGATAAGT TGTCGATCGA ACAGAAGATT TTCATCCGTC GCTCGGACGG TAGAGTCCAC 
TTGGCGGAGA TTATCAAACT GGAGGGCGGT GACTCCAAGC TGATTACGGT GGAGTGGCCC 
GAAGGACATA CGGTGCGTGG TAAGGAACTG CCCCTGGAGC TGGTGGTCCT GATGAATCCT 
CATATCTTCG ACTCGCCCCG CTGCAGTGGC GGCAATGCGG CGTCAGCCAA TCAAACTGCC 
TCCATATCGC CACGTTCAAT GAAACAACGA ATAGCGACTG GGAGCTTATC TCCTGTACTG 
GCCACTGCCC CGCCACGCCA GCAGACGGCG CCGCCAGTTC GAGAGGACGA GGTGGTGCAC 
CAGGCTGAAA GAATGCGAAA AGAACGGGAA CGGAGGCGAG AAGCACAAGC CAGGACTCGT 
CTAGATCGGG AGCAGGGGAA GAACGAAGAT CCGGGAAATC CCAACTGGGA AGTAGCCAGA 
ATGATACGAC TGCAACGCGA GCAAATGGAG AGTCAGCGGG TGAGAAGTGG TACTACGAAC 
GAACGAATCA ATTGCCACCA AATTATGGTT TGTGTGAGGA AGAGACCACT GAGGCGCAAG 
GAGCTGGCTG ACCGGGAACA GGATGTGGTC AGCATTCCGT CTAAGCACAC ATTGGTGGTC 
CACGAGCCCC GCAAGCATGT GAACCTGGTC AAGTTCCTGG AAAATCATAG CTTCCGTTTC 
GATTACGTCT TCGACGAGGA GTGCTCCAAT GCCACGGTCT ACGAATTCAC AGCCCGACCC 
TTGATAAAGC ACATTTTTGA TGGCGGAATG GCCACGTGTT TCGCCTACGG ACAAACTGGA 
AGCGGCAAGA CCTATACGAT GGGTGGTCAG TTCCCCGGAA GGCATCAGAG CTCAATGGAT 
GGCATCTATG CAATGGCCGC TAAGGACGTG TTCTCCACTC TAAAGACGGT TCCCTATAAC 
AAGCTTAATC TGAAAGTTTA CTGCAGCTTC TTCGAGATCT ACGGCACCCG GGTGTTCGAT 
CTCCTGATGC CTGGCAAGCC ACAACTGCGT GTCTTGGAGG ATAGAAACCA GCAGGTGCAA 
GTGGTGGGCC TCACCCAGAA TCCAGTACAG AACACCGCCG AAGTTCTGGA CCTACTCGAG 
TTGGGCAATA GTGTCCGAAC CTCGGGTCAC ACCTCTGCCA ATTCCAAGTC CTCCCGATCG 
CATGCTGTGT TCCAAATCGT GCTGAGATCC GCGGCGGGCG AGAAGCTACA CGGGAAATTC 
TCGCTTATAG ATCTGGCCGG GAATGAAAGA GGAGCGGACA ACAGCTCGGC GGATCGACAG 
ACGCGCCTGG AAGGATCCGA GATCAATAAA TCGCTGCTGG TCCTCAAGGA ATGCATTCGC 
GCTCTGGGGC GCCAGTCGAG TCATTTGCCA TTCCGTGGCT CCAAGCTGAC CCAAGTCCTG 
CGGGACTCCT TCATCGGAGG TAAGAAGGTG AAAACCTGCA TGATAGCCAT GATCTCGCCA 
TGCTTGCATT CGGTGGAGCA TACCTTGAAC ACGCTGCGTT ATGCGGATCG GGTGAAGGAA 
CTAAGTGTGG AGTCGATCCC ATCTAAACGG ATGCCCGATG CCAACCTTGG AAGCACTTCC 
ATGTCAGATA TTGTTTGCCA GTCGTCCACC CAGCGACTCT TTCCATGTGC CTCCTCCACA 
TCGATGCCAG GTGGTGGCAA CCAAGCGCAG CAACACACCA ACACCGCGAA CGACTTGAAC 
AGATCCCAGA AACCAACATC TAAGCCCACT TATCCCACAT CCGGTCAGCA GCTGGTCCAG 
AGGAAGGGAA GCTCCCAACG GGAGGCCTCC ATGATGCTGA CCAAATCCCT GGCACAATTC 
CGAGGGCGCA ACTTTCCCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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Klp59C cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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