edl cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	edl
Entrez Gene ID	37149
Full Name	ETS-domain lacking
Synonyms	CG15085,Dmel\CG15085,EDL,Edl,MAE,Mae,anon-WO02077276.2,anon-WO02077276.3,edl/mae,l(2)k06602,mae
General protein information	Preferred Names ETS-domain lacking Names CG15085 gene product from transcript CG15085-RA CG15085-PA Ets domain lacking edl-PA modulator of the activity of Ets
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 2R Map Location: 55E6-55E6

mRNA and Protein(s)

mRNA	Protein	Name
NM_079062.3	NP_523786.2	ETS-domain lacking

Pathways from BioSystems

Homologies

Drosophila melanogaster (fruit fly)	edl	NP_523786.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP005734	XP_556387.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Efficient phosphorylation and consequent activation of Pnt-P2 requires a three-dimensional docking surface on its SAM domain for the MAP kinase but Mae binding to Pnt-P2 occludes this docking surface.
Title: Mae inhibits Pointed-P2 transcriptional activity by blocking its MAPK docking site.

prior to Ras activation, the Mae/Yan interaction blocks premature nuclear export of Yan monomers
Title: Antagonistic regulation of Yan nuclear export by Mae and Crm1 may increase the stringency of the Ras response.

A dual positive and negative regulator of RTK-mediated signaling.
Title: MAE, a dual regulator of the EGFR signaling pathway, is a target of the Ets transcription factors PNT and YAN.

Depolymerization of Yan by Mae represents a novel mechanism of transcriptional control that sensitizes Yan for regulation by receptor tyrosine kinases.
Title: Derepression by depolymerization; structural insights into the regulation of Yan by Mae.

The following edl gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the edl cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa10518	NM_079062.3 Latest version!	Drosophila melanogaster ETS-domain lacking (edl), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

edl ( NM_079062.3 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_523786.2 Drosophila melanogaster ETS-domain lacking (edl), mRNA.

Price & Availability↑

CloneID	OFa10518
Clone ID Related Accession (Same CDS sequence)	NM_079062.3
Accession Version	NM_079062.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 534bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	ETS-domain lacking
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033778). On Jul 15, 2014 this sequence version replaced NM_079062.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGCAAGTGG AATCGAGCTA TACCAAATAT GCCGGACGTG TGCCACCTTT GGACCTCACC 
CAGGTGAATG GTGGCCAAGA TTTGTGGGGC GGCAATGGTG GCGGCAATAA CGCATCCGCC 
AGACGCCATC TGCATCATCC CTATCAAATG CTGGACAAGT GCCGCGGCGG AGTAACCCTG 
ATCAGTGCAT CATCCGCCAT CTCATCTACA TCCAACTCCT CCGACGACAA TAACAATCGA 
CTGATGAGCG CTGATGATGG CACCACCAGT CTGCTGCATC CCTTGGGCTC CGATGGTCTG 
CCTCTGGATC CGCGCGATTG GACGCGAGCG GATGTCTGGA AATGGCTCAT CAATATGGCC 
GTATCCGAGG GATTGGAGGT CACCGCCGAA CTGCCACAGA AATTCCCCAT GAACGGCAAG 
GCATTGTGCC TGATGAGTCT CGATATGTAC CTGTGCCGAG TTCCCGTGGG CGGCAAGATG 
CTCTACCGCG ACTTCCGGGT GCGACTCGCC CGAGCAATGG CCCTGCTATC ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_523786.2
CDS	619..1152
Translation	MQVESSYTKYAGRVPPLDLTQVNGGQDLWGGNGGGNNASARRHLHHPYQMLDKCRGGVTLISASSAISSTSNSSDDNNNRLMSADDGTTSLLHPLGSDGLPLDPRDWTRADVWKWLINMAVSEGLEVTAELPQKFPMNGKALCLMSLDMYLCRVPVGGKMLYRDFRVRLARAMALLS

Target ORF information:

RefSeq Version	NM_079062.3
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster ETS-domain lacking (edl), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_079062.3

ORF Insert Sequence:

ATGCAAGTGG AATCGAGCTA TACCAAATAT GCCGGACGTG TGCCACCTTT GGACCTCACC 
CAGGTGAATG GTGGCCAAGA TTTGTGGGGC GGCAATGGTG GCGGCAATAA CGCATCCGCC 
AGACGCCATC TGCATCATCC CTATCAAATG CTGGACAAGT GCCGCGGCGG AGTAACCCTG 
ATCAGTGCAT CATCCGCCAT CTCATCTACA TCCAACTCCT CCGACGACAA TAACAATCGA 
CTGATGAGCG CTGATGATGG CACCACCAGT CTGCTGCATC CCTTGGGCTC CGATGGTCTG 
CCTCTGGATC CGCGCGATTG GACGCGAGCG GATGTCTGGA AATGGCTCAT CAATATGGCC 
GTATCCGAGG GATTGGAGGT CACCGCCGAA CTGCCACAGA AATTCCCCAT GAACGGCAAG 
GCATTGTGCC TGATGAGTCT CGATATGTAC CTGTGCCGAG TTCCCGTGGG CGGCAAGATG 
CTCTACCGCG ACTTCCGGGT GCGACTCGCC CGAGCAATGG CCCTGCTATC ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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edl cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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